Nuclear drug injection automatic administration equipment and use method thereof

Abstract

The invention discloses nuclear drug injection automatic drug delivery equipment which comprises a drug delivery equipment body and an accurate drug delivery system. The precise dosing system specifically comprises a liquid medicine processing module, a liquid medicine feeding module and a liquid medicine feeding module, wherein the liquid medicine processing module is responsible for full-flow control of extraction, dilution, compensation and injection of liquid medicine; the sensor and detection module is used for collecting the physical property parameters, the flow state and the in-vivo and in-vitro radioactive dose of the liquid medicine in real time; the data processing and control module is used for dynamically calculating the compensation amount, predicting the residual amount and executing safety control; the safety and exception handling module is used for monitoring exceptions in real time and triggering safety braking; the data storage and communication module is used for storing operation data and supporting remote supervision; and the user interface and monitoring module is used for providing operation interaction and real-time state display. According to the invention, through the core technologies of dynamic concentration compensation, tube wall residue prediction, bimodal monitoring, block chain evidence storage and the like, a set of nuclear drug injection administration system with full-process automation, high precision and high safety is constructed.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and particularly to an automated drug delivery device for nuclear medicine injection and its usage method. Background Art

[0002] As an important means of modern medical diagnosis and treatment, nuclear medicine widely relies on the precise application of radioactive drugs (nuclear drugs). For example, in tumor imaging, cardiovascular disease assessment, and neurological function research, nuclear drugs can provide highly sensitive biological metabolism information through their radioactive tracer characteristics. However, the particularity of nuclear drugs, such as short half-life, rapid decay of radioactive activity, and strict dosage requirements, poses extremely high requirements for the precision, safety, and real-time control capabilities of drug delivery devices.

[0003] Traditional drug delivery devices mostly rely on manual operation or semi-automated systems, calculating the liquid medicine volume through fixed algorithms. They do not consider that nuclear drugs are prone to residue on the inner wall of the pipeline due to factors such as viscosity, resulting in drug waste. Calculating the liquid medicine volume only through simple fixed algorithms is prone to errors, and the control precision of the liquid medicine volume needs to be improved. Summary of the Invention

[0004] The purpose of this part is to outline some aspects of the embodiments of the present invention and briefly introduce some preferred embodiments. Simplifications or omissions may be made in this part, as well as in the abstract and title of the present application, to avoid obscuring the purpose of this part, the abstract, and the title. However, such simplifications or omissions cannot be used to limit the scope of the present invention.

[0005] To solve the above technical problems, the present invention provides the following technical solutions:

[0006] In a first aspect, an embodiment of the present invention provides an automated drug delivery device for nuclear medicine injection, including:

[0007] A drug delivery device body;

[0008] An accurate drug delivery system, specifically including:

[0009] A liquid medicine processing module: responsible for the whole process control of liquid medicine extraction, dilution, compensation, and injection;

[0010] A sensor and detection module: real-time collecting physical property parameters of the liquid medicine, flow state, and radioactive doses inside and outside the body;

[0011] A data processing and control module: dynamically calculating the compensation amount, predicting the residue amount, and performing safety control;

[0012] A safety and anomaly handling module: real-time monitoring anomalies and triggering safety braking;

[0013] A data storage and communication module: storing operation data and supporting remote supervision;

[0014] User interface and monitoring module: Provide operation interaction and real-time status display.

[0015] As a preferred solution of the automated nuclear medicine injection device described in the present invention, wherein: the drug delivery device body includes: a housing, on which a first valve, a second valve, a third valve, a fourth valve, a fifth valve, a peristaltic pump and a bubble sensor are respectively provided. A multi-channel hose is commonly arranged on the first valve, the second valve, the third valve, the fourth valve, the fifth valve, the peristaltic pump and the bubble sensor. A syringe is provided on one side of the housing, a syringe pusher is provided above the syringe, a pressure sensor is arranged inside the syringe, a device switch is arranged on the housing. The multi-channel hose at the first valve is connected to a normal saline bag, the multi-channel hose at the third valve is connected to a liquid medicine bottle, the multi-channel hose at the fifth valve is connected to a patient infusion tube, the multi-channel hose at the peristaltic pump is connected to a measuring bottle, an activity meter is arranged inside the measuring bottle, and the multi-channel hose at the bubble sensor is communicated with the syringe.

[0016] In a second aspect, the embodiment of the present invention also provides a method for using an automated nuclear medicine injection device, which specifically includes the following steps:

[0017] S1. The liquid medicine processing module controls the peristaltic pump to extract a quantitative liquid medicine into the measuring bottle to detect the radioactive concentration value of the liquid medicine, and the data processing and control module calculates the volume of the medicine required for the target radiation dose according to the current radioactive concentration;

[0018] S2. The sensor and detection module collects information related to the liquid medicine, and calculates the residual amount on the pipe wall through the prediction model of the data processing and control module;

[0019] S3. The data processing and control module dynamically calculates the replenishment amount according to the volume of the medicine required for the target radiation dose calculated in S1 and the residual amount on the pipe wall predicted in S2;

[0020] S4. Based on the replenishment amount, perform the operation of supplementing and sucking back the liquid medicine and reach the target concentration;

[0021] S5. The liquid medicine processing module pumps the liquid medicine reaching the target concentration and mixes it with normal saline into the syringe through the peristaltic pump;

[0022] S6. The liquid medicine processing module injects the medicine in the syringe into the patient, and real-time monitors the change of the radiation count on the anterior chest body surface of the patient after injection through a probe;

[0023] S7. Generate a flow rate-pressure dynamic curve in real time during the injection process, detect abnormalities and trigger safety braking.

[0024] As a preferred embodiment of the method for using an automated drug administration device for nuclear medicine injection according to the present invention, in which: the calculation formula for the required volume of the drug in S1 is as follows:

[0025]

[0026] where D tar get is the target radiation dose, and C current is the currently detected concentration;

[0027] The calculation formula for the residual amount on the pipe wall in S2 is as follows:

[0028]

[0029] where: R is the residual amount on the pipe wall; β is the coefficient calibrated through experimental data; α is the coefficient of the hydrophobic coating on the inner wall of the pipe; μ is the viscosity of the liquid medicine; v is the flow rate of the liquid medicine; T is the ambient temperature.

[0030] As a preferred embodiment of the method for using an automated drug administration device for nuclear medicine injection according to the present invention, in which: the calculation formula for the replenishment amount in S3 is as follows:

[0031] Q comp = V need - V system_initial - R;

[0032] where: Q comp is the replenishment amount; V system_initial is the initial amount of the system liquid medicine extracted when detecting the radioactive concentration value of the liquid medicine.

[0033] As a preferred embodiment of the method for using an automated drug administration device for nuclear medicine injection according to the present invention, in which: when the replenishment amount Q comp > 0, the liquid medicine is supplemented by the clockwise rotation of the peristaltic pump; when the replenishment amount Q comp < 0, the excess liquid medicine is aspirated back by the counterclockwise rotation of the peristaltic pump.

[0034] As a preferred embodiment of the method for using an automated drug administration device for nuclear medicine injection according to the present invention, in which: S5 specifically includes the following steps:

[0035] a. Pump the liquid medicine reaching the target concentration into the syringe by the counterclockwise rotation of the peristaltic pump;

[0036] b. Pump the normal saline into the measuring bottle by the clockwise rotation of the peristaltic pump;

[0037] c. Pump the normal saline in the measuring bottle into the syringe by the counterclockwise rotation of the peristaltic pump.

[0038] As a preferred embodiment of the method for using an automated drug administration device for nuclear medicine injection according to the present invention, wherein: in step S6, the radiation count change on the anterior chest surface of the patient is monitored in real time, and when the change amplitude is abnormal, a safety brake is triggered.

[0039] As a preferred embodiment of the method for using an automated drug administration device for nuclear medicine injection according to the present invention, wherein: in step S7, the anomaly detection includes identifying the slope mutation and pressure overlimit of the flow rate-pressure dynamic curve through an AI algorithm, determining leakage and blockage, and promptly stopping the medication to ensure the medication safety of the patient.

[0040] As a preferred embodiment of the method for using an automated drug administration device for nuclear medicine injection according to the present invention, it further includes encrypting and storing the radioactive concentration deviation, wall residue amount, and replenishment amount to the blockchain to achieve the immutability of operation data.

[0041] Advantages of the present invention:

[0042] Through core technologies such as dynamic concentration compensation, wall residue prediction, dual-modal monitoring, and blockchain evidence storage, the present invention constructs a set of fully automated, high-precision, and high-safety drug administration systems for nuclear medicine injections. It can accurately proportion the appropriate concentration of the liquid medicine under the continuous decay of the nuclear medicine, ensuring the accuracy of the liquid medicine measurement. At the same time, it improves the medication safety and meets the core requirements of the nuclear medicine field for efficient, compliant, and personalized treatment. BRIEF DESCRIPTION OF THE DRAWINGS

[0043] In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the following will briefly introduce the drawings required for the description of the embodiments. Obviously, the following drawings are only some embodiments of the present invention. For those of ordinary skill in the art, without creative efforts, other drawings can be obtained based on these drawings. Among them:

[0044] Figure 1 is a front overall structural schematic diagram of an automated drug administration device for nuclear medicine injection proposed by the present invention;

[0045] Figure 2 is a principle structural schematic diagram of an automated drug administration device for nuclear medicine injection proposed by the present invention;

[0046] Figure 3 is a flow architecture diagram of the method for using an automated drug administration device for nuclear medicine injection proposed by the present invention;

[0047] In the figure: 100, the main body of the drug administration device; 101, the housing; 102, the first valve; 103, the second valve; 104, the third valve; 105, the fourth valve; 106, the fifth valve; 107, the peristaltic pump; 108, the bubble sensor; 109, the multi-channel hose; 110, the syringe; 111, the injector; 112, the device switch. Detailed implementation manners

[0048] To make the above objects, features, and advantages of the present invention more obvious and understandable, the following detailed description of the specific implementation manners of the present invention will be given with reference to the accompanying drawings of the specification.

[0049] In the following description, many specific details are set forth to fully understand the present invention. However, the present invention can also be implemented in other ways different from those described herein. Those skilled in the art can make similar generalizations without departing from the connotation of the present invention. Therefore, the present invention is not limited by the specific embodiments disclosed below.

[0050] Embodiment 1

[0051] Referring to Figure 1-2 , the present invention provides an automated drug administration device for nuclear medicine injection solution, comprising:

[0052] The drug delivery device body 100 includes: a housing 101, on which a first valve 102, a second valve 103, a third valve 104, a fourth valve 105, a fifth valve 106, a peristaltic pump 107 and a bubble sensor 108 are respectively provided. A multi-channel hose 109 is commonly arranged on the first valve 102, the second valve 103, the third valve 104, the fourth valve 105, the fifth valve 106, the peristaltic pump 107 and the bubble sensor 108. A syringe 110 is provided on one side of the housing 101, a syringe driver 111 is provided above the syringe 110, a pressure sensor is arranged inside the syringe 110, and a device switch 112 is provided on the housing 101. The multi-channel hose 109 at the first valve 102 is connected to a normal saline bag, the multi-channel hose 109 at the third valve 104 is connected to a medicine bottle, the multi-channel hose 109 at the fifth valve 106 is connected to a patient infusion tube. A flow sensor is arranged inside the peristaltic pump 107 for sensing the flow rate of the medicine. The multi-channel hose 109 at the peristaltic pump 107 is connected to a measuring bottle, and an activity meter is arranged inside the measuring bottle. The multi-channel hose 109 at the bubble sensor 108 is communicated with the syringe 110. A quantitative amount of the medicine liquid is extracted by the peristaltic pump 107 into the measuring bottle for concentration detection, and then the replenishment amount is obtained through calculation. When the replenishment amount is positive, the peristaltic pump 107 rotates clockwise to supplement the medicine liquid. When the replenishment amount is negative, the peristaltic pump 107 rotates counterclockwise to aspirate the excess medicine liquid. Then the fourth valve 105 is opened to input the medicine liquid into the syringe 110. Then the fourth valve 105 is closed, the first valve 102 is opened to aspirate normal saline into the measuring bottle, and then the fourth valve 105 is opened to inject the normal saline in the measuring bottle into the syringe 110. Then the syringe 110 is pressed by the syringe driver 111, and at the same time the fourth valve 105 and the second valve 103 are opened until the bubble sensor 108 detects the medicine liquid, then the fourth valve 105 and the second valve 103 are closed and the fifth valve 106 is opened to inject the medicine into the patient. At the same time, when the bubble sensor 108 detects a bubble during the injection process, the fifth valve 106 is closed, the fourth valve 105 and the second valve 103 are opened to discharge the bubble, and then the fifth valve 106 is opened again to inject the medicine;

[0053] The precise drug delivery system 200 specifically includes:

[0054] The medicine liquid processing module: responsible for the whole process control of medicine liquid extraction, dilution, compensation and injection, and realizing millisecond-level medicine liquid adjustment through the control strategy of the peristaltic pump and the coordination of the valves;

[0055] The sensor and detection module: real-time collecting the physical property parameters, flow state and in-vivo and in-vitro radioactive doses of the medicine liquid, fusing multi-modal data including concentration, flow rate, pressure and temperature, and at the same time comparing and feeding back the doses in-vivo and in-vitro;

[0056] Data processing and control module: Dynamically calculate the compensation amount, predict the remaining amount and execute safety control. Through the prediction model and the calculation model of the replenishment amount, accurately calculate the replenishment amount of the liquid medicine and transmit the command to the peristaltic pump;

[0057] Safety and exception handling module: Monitor exceptions in real time and trigger safety braking. When administering medicine to a patient, monitor in real time to ensure the safety of the medication process;

[0058] Data storage and communication module: Store operation data and support remote supervision, ensure the immutability of data, and facilitate later auditing work;

[0059] User interface and monitoring module: Provide operation interaction and real-time status display, and display the medication situation in real time for convenient intuitive observation by staff.

[0060] Embodiment 2

[0061] Refer to Figure 3 , the present invention provides a method for using an automated drug administration device for nuclear medicine injection, which specifically includes the following steps:

[0062] S1. The liquid medicine processing module controls the peristaltic pump 107 to extract a quantitative liquid medicine into the measuring bottle to detect the radioactive concentration value of the liquid medicine. The data processing and control module rotates the peristaltic pump 107 clockwise to extract a quantitative liquid medicine to detect the current radioactive concentration, and calculates the volume of the medicine required for the target radiation dose according to the current radioactive concentration; The calculation formula for the required medicine volume is as follows:

[0063]

[0064] Where D tar get is the target radiation dose, and C current is the currently detected concentration;

[0065] S2. The sensor and detection module collect information related to the liquid medicine, including the viscosity of the liquid medicine, the pipe material coefficient, the flow rate, and the temperature, and calculate the residual amount on the pipe wall through the prediction model of the data processing and control module. The calculation formula for the residual amount on the pipe wall is as follows:

[0066]

[0067] Wherein: R is the residual amount on the pipe wall; β is a coefficient calibrated through experimental data, which is used to fit the experimental data, correct the prediction error of the theoretical model, and implicitly has the function of unit conversion; α is the coefficient of the hydrophobic coating on the inner wall of the pipe; μ is the viscosity of the liquid medicine, reflecting the flow resistance of the liquid medicine; v is the flow rate of the liquid medicine, which directly affects the contact time between the liquid medicine and the pipe wall; T is the ambient temperature, which affects the viscosity and fluidity of the liquid medicine; this formula quantifies the key factors affecting the residual amount on the pipe wall through a multi-physical field coupling model. For example, high viscosity and low flow rate will increase the adhesion time between the liquid medicine and the pipe wall, resulting in an increase in the residual amount; the increase in temperature may reduce the viscosity, thereby reducing the residual; the setting of the hydrophobic coating can significantly reduce the residual amount; this formula integrates the physical properties of the liquid medicine, flow parameters, environmental parameters, and pipe materials, avoiding the limitations of traditional single empirical estimations; at the same time, by inputting the real-time collected data into the model, the predicted value of the residual can be dynamically corrected to adapt to different batches of liquid medicine and operating conditions.

[0068] S3. The data processing and control module dynamically calculates the replenishment amount according to the volume of the medicine required for the target radiation dose calculated in S1 and combines the residual amount on the pipe wall predicted in S2, and performs the necessary replenishment in combination with the deviation between the detected value and the target value and the residual amount in the pipe wall, so as to be able to more accurately control the dose of the liquid medicine; the formula for calculating the replenishment amount is as follows:

[0069] Q comp =V need -V system_initial -R;

[0070] Wherein: Q comp is the replenishment amount; V system_initial is the initial amount of the system liquid medicine extracted when detecting the radioactive concentration value of the liquid medicine; this formula linearly superimposes the influence of the concentration deviation and the residual on the pipe wall to achieve multi-parameter joint compensation; at the same time, it solves the problems of concentration deviation and residual loss. Most traditional methods only adjust for a single factor; further, when the replenishment amount Q comp >0, the peristaltic pump 107 rotates clockwise to supplement the liquid medicine; when the replenishment amount Q comp <0, the peristaltic pump 107 rotates counterclockwise to suck back the excess liquid medicine; the rotation direction of the peristaltic pump 107 directly corresponds to the supplement and suck-back actions, without complex control logic, reducing the complexity of the system. Combining the dynamically calculated replenishment amount ensures the accuracy of the liquid medicine supplement and suck-back amount.

[0071] S4. Execute the supplement and suck-back operations of the liquid medicine based on the replenishment amount and reach the target concentration.

[0072] S5. The liquid medicine treatment module uses a peristaltic pump 107 to pump the liquid medicine that has reached the target concentration and normal saline into the syringe 110, and flushes the pipeline and the detection bottle with normal saline to avoid residual liquid medicine, further precisely controlling the dosage of the liquid medicine. The specific steps are as follows:

[0073] a. Pump the liquid medicine that has reached the target concentration into the syringe 110 by the counterclockwise rotation of the peristaltic pump 107;

[0074] b. Draw normal saline into the measuring bottle by the clockwise rotation of the peristaltic pump 107;

[0075] c. Pump the normal saline in the measuring bottle into the syringe 110 by the counterclockwise rotation of the peristaltic pump, and flush the residual liquid medicine in the pipe wall and the measuring bottle by pumping in and out the normal saline, avoiding the loss of liquid medicine caused by drug delivery and precisely controlling the dosage of the liquid medicine;

[0076] S6. The liquid medicine treatment module injects the medicine in the syringe 110 into the patient and real-time monitors the change of the radiation count on the surface of the patient's precordial area after injection; ensuring that the medicine smoothly enters the patient's body and ensuring the safety of medication. When the change amplitude is abnormal, a safety brake is triggered to monitor the change of the radiation count on the surface of the patient's precordial area. When the liquid medicine enters the body through the blood vessel, the radiation count on the patient's precordial area rises dynamically and finally reaches a stable count, so as to ensure that the liquid medicine is smoothly injected into the patient's body. When a blood vessel rupture occurs during the injection process, it can be detected in time and the injection can be stopped to ensure the safety of the patient's medication.

[0077] S7. During the injection process, a flow rate-pressure dynamic curve is generated in real time to detect abnormalities and trigger a safety brake to avoid unexpected situations during the medication process and ensure the safety of the patient. The abnormal detection includes identifying the slope mutation and pressure overlimit of the flow rate-pressure dynamic curve through an AI algorithm, determining leakage and blockage, and stopping the medication in time to ensure the safety of the patient's medication. The pressure sensor is integrated at the piston of the syringe 110 to collect the pressure value in real time. The displacement sensor monitors the piston displacement of the syringe 110, calculates the real-time flow rate by combining the timestamp, and synchronously plots the pressure and flow rate curves with time as the horizontal axis. At the same time, leakage, blockage and other scenarios are artificially created in the experimental environment, and the corresponding curves are collected.

[0078] Furthermore, it also includes encrypting and storing the radioactive concentration deviation, wall tube residue amount, and replenishment amount in the blockchain to achieve the immutability of operation data. The blockchain technology ensures that once the data is recorded, it cannot be modified, meeting the strict compliance requirements of radiopharmaceutical regulation and enhancing the data credibility of medical institutions. At the same time, the timestamps and detailed parameters of all operation steps are traceable, facilitating accident investigation and auditing. The regulatory authorities can directly retrieve the blockchain data, simplifying the regulatory review process. The encrypted storage method protects sensitive medical data from leakage and abuse.

[0079] In summary, through core technologies such as dynamic concentration compensation, wall tube residue prediction, dual-modal monitoring, and blockchain evidence storage, the present invention constructs a full-process automated, high-precision, and high-security radiopharmaceutical injection administration system. It can accurately proportion the liquid medicine with a suitable concentration under the continuous decay of the radiopharmaceutical, ensuring the accuracy of the liquid medicine measurement. At the same time, it improves the safety of medication, meeting the core needs of the nuclear medicine field for efficient, compliant, and personalized treatment.

[0080] It should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention and not to limit them. Although the present invention has been described in detail with reference to the preferred embodiments, those of ordinary skill in the art should understand that the technical solutions of the present invention can be modified or equivalently replaced without departing from the spirit and scope of the technical solutions of the present invention, and they should all be covered by the scope of the claims of the present invention.

Claims

1. An automated drug administration device for nuclear medicine injection, characterized in that: Comprising: The main body of the drug administration device (100); An accurate drug administration system (200), specifically including: Liquid medicine processing module: Responsible for the whole process control of liquid medicine extraction, dilution, compensation and injection; Sensor and detection module: Real-time collection of liquid medicine physical property parameters, flow state and in-vivo and in-vitro radioactive doses; Data processing and control module: Dynamically calculate the compensation amount, predict the residual amount and execute safety control; Safety and anomaly handling module: Real-time monitor anomalies and trigger safety braking; Data storage and communication module: Store operation data and support remote supervision; User interface and monitoring module: Provide operation interaction and real-time status display.

2. The automated drug administration device for nuclear medicine injection according to claim 1, characterized in that: The main body of the drug administration device (100) includes: a housing (101), on which a first valve (102), a second valve (103), a third valve (104), a fourth valve (105), a fifth valve (106), a peristaltic pump (107) and a bubble sensor (108) are respectively provided. A multi-channel hose (109) is commonly arranged on the first valve (102), the second valve (103), the third valve (104), the fourth valve (105), the fifth valve (106), the peristaltic pump (107) and the bubble sensor (108). A syringe (110) is provided on one side of the housing (101), and a syringe driver (111) is provided above the syringe (110). A pressure sensor is arranged in the syringe (110). An equipment switch (112) is provided on the housing (101). The multi-channel hose (109) at the first valve (102) is connected to a physiological saline bag. The multi-channel hose (109) at the third valve (104) is connected to a liquid medicine bottle. The multi-channel hose (109) at the fifth valve (106) is connected to a patient infusion tube. The multi-channel hose (109) at the peristaltic pump (107) is connected to a measuring bottle, and an activity meter is arranged in the measuring bottle. The multi-channel hose (109) at the bubble sensor (108) is communicated with the syringe (110).

3. A method for using an automated drug administration device for nuclear medicine injection, based on the automated drug administration device for nuclear medicine injection according to any one of claims 1-2, characterized in that: Specifically including the following steps: S1. The liquid medicine processing module controls the peristaltic pump (107) to extract a quantitative liquid medicine into the measuring bottle to detect the radioactive concentration value of the liquid medicine. The data processing and control module calculates the volume of the medicine required for the target radiation dose according to the current radioactive concentration; S2. The sensor and detection module collects information related to the liquid medicine, and calculates the residual amount on the pipe wall through the prediction model of the data processing and control module; S3. The data processing and control module dynamically calculates the replenishment amount according to the volume of the medicine required for the target radiation dose calculated in S1 and the residual amount on the pipe wall predicted in S2; S4. Based on the replenishment amount, perform the operation of liquid medicine supplementation and back suction and reach the target concentration; S5. The liquid medicine processing module pumps the liquid medicine reaching the target concentration and mixes it with physiological saline into the syringe (110) through the peristaltic pump (107); S6. The liquid medicine processing module injects the medicine in the syringe (110) into the patient, and real-time monitors the change of the radiation count on the anterior chest surface of the patient after injection through a probe; Ensure that the medicine smoothly enters the patient's body and ensure the safety of drug use. S7. Generate a flow rate - pressure dynamic curve in real time during the injection process, detect abnormalities and trigger safety braking.

4. A method for using an automated drug administration device for radiopharmaceutical injection according to claim 3, characterized in that: The calculation formula for the required drug volume in S1 is as follows: Among them, D target is the target radiation dose, and C current is the current detected concentration; The calculation formula for the residual amount on the pipe wall in S2 is as follows: Where: R is the residual amount on the pipe wall; β is the coefficient calibrated through experimental data; α is the coefficient of the hydrophobic coating on the inner wall of the pipe; μ is the viscosity of the liquid medicine; v is the flow rate of the liquid medicine; T is the ambient temperature.

5. The usage method of an automated drug administration device for nuclear medicine injection according to claim 4, characterized in that: The calculation formula for the replenishment amount in S3 is as follows: Q comp = V need - V system_initial - R; Where: Q comp is the supply amount; V system_initial is the initial system liquid medicine amount extracted when detecting the radioactive concentration value of the liquid medicine.

6. The usage method of an automated drug administration device for nuclear medicine injection according to claim 5, characterized in that: The replenishment amount Q comp When > 0, the medicinal liquid is supplemented by the clockwise rotation of the peristaltic pump (107); the replenishment amount Q comp < 0, the excess medicinal liquid is aspirated back by the counterclockwise rotation of the peristaltic pump (107).

7. A method for using an automated drug administration device for nuclear medicine injection according to claim 6, characterized in that: S5 specifically includes the following steps: a. Pump the liquid medicine reaching the target concentration into the syringe (110) by the counterclockwise rotation of the peristaltic pump (107); b. Draw physiological saline into the measuring bottle by the clockwise rotation of the peristaltic pump (107); c. Pump the physiological saline in the measuring bottle into the syringe (110) by the counterclockwise rotation of the peristaltic pump.

8. A method for using an automated drug administration device for nuclear medicine injection according to claim 7, characterized in that: In S6, the change in the body surface radiation count in the patient's precordial area is monitored in real time, and when the change amplitude is abnormal, safety braking is triggered.

9. The method for using an automated drug administration device for nuclear medicine injection according to claim 1, wherein: In S7, the abnormality detection includes identifying the slope mutation and pressure over - limit of the flow rate - pressure dynamic curve through an AI algorithm, determining leakage and blockage, and promptly stopping the medication to ensure the medication safety of the patient.

10. A method for using an automated drug administration device for nuclear medicine injection according to claim 9, characterized in that: It also includes encrypting and storing the radioactive concentration deviation, the residual amount on the pipe wall, and the replenishment amount in the blockchain to achieve the immutability of operation data.

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