Cistanche deserticola and dendrobium officinale tablet and preparation method thereof

Abstract

The invention discloses herba cistanche and dendrobium officinale tablets and a preparation method thereof, and belongs to the field of health food manufacturing. The tablet takes 500g of cistanche, 300g of dendrobium officinale and 200g of American ginseng as main medicines, and mannitol, microcrystalline cellulose and other auxiliary materials are matched. Effective components of the medicinal materials are extracted through two times of decoction, auxiliary materials are added after concentration, tablets are prepared, and the tablets are subpackaged according to 5g per bag. The compatibility of the main medicines can regulate the balance of yin and yang, tonify kidney yang, benefit essence and blood, relax bowel, tonify stomach, promote salivation, nourish yin, clear heat and enhance immunity, and the traditional Chinese medicine composition is mild in medicine property, nourishes yin but not greasy, warms yang but not dry, and is especially suitable for middle-aged and elderly people. The preparation process guarantees the maximization of the drug effect, and the four types of auxiliary materials have a synergistic effect, so that the tablet has good formability and disintegration, is suitable for people with hyperglycemia, is convenient to take, good in taste, high in stability in storage and transportation, and sufficient in absorption of effective components, and provides a safe and efficient health maintenance product for sub-health people.

Description

Technical Field

[0001] The present invention relates to the field of health food manufacturing, and specifically discloses a Cistanche deserticola and Dendrobium officinale tablet and a preparation method thereof. Background Art

[0002] With the acceleration of the modern life rhythm, the intensification of work pressure, and the influence of environmental pollution and other factors, the number of sub-healthy people has been continuously increasing. According to the survey of the World Health Organization, about 75% of the global population is in a sub-healthy state, showing symptoms such as listlessness, decreased immunity, fatigue and weakness, and the discomfort manifestations related to "deficiency syndromes" in traditional Chinese medicine theory are particularly prominent. Cistanche deserticola, Dendrobium officinale, and American ginseng, as traditional Chinese medicinal materials, have unique advantages in regulating deficiency syndromes. Cistanche deserticola warms the kidney yang, Dendrobium officinale nourishes yin and promotes the production of body fluid, and American ginseng supplements qi and nourishes yin. The synergistic effect of the three can effectively improve the state of physical deficiency and meet the health care needs of contemporary people.

[0003] However, there are many problems with the related products on the current market that use Cistanche deserticola, Dendrobium officinale, and American ginseng as raw materials. When using traditional Chinese medicinal material decoctions, it is necessary to carry out cumbersome decoction, which is time-consuming and laborious, and it is difficult to ensure the dissolution rate of active ingredients, and the efficacy is unstable; although some products such as granules and oral liquids have improved in terms of convenience of taking, their taste is poor, and the bitter taste of the medicinal materials themselves affects the acceptance of consumers, resulting in insufficient compliance. In addition, there are limitations in the preparation process of existing traditional Chinese medicine preparations, such as serious loss of active ingredients during the extraction process and unreasonable selection of excipients, resulting in low bioavailability of the products and difficult to achieve efficient absorption; during storage, it is easily affected by environmental factors such as humidity and temperature, and quality problems such as moisture absorption and caking, and degradation of active ingredients occur, restricting the market promotion and application of the products.

[0004] Therefore, it is necessary to develop a Cistanche deserticola and Dendrobium officinale tablet to solve the above problems. Summary of the Invention

[0005] The purpose of the present invention is to provide a Cistanche deserticola and Dendrobium officinale tablet and a preparation method thereof.

[0006] To achieve the above purpose, the present invention provides the following technical solutions: A Cistanche deserticola and Dendrobium officinale tablet, which is made from the following raw materials in parts by weight: 500 g of Cistanche deserticola, 300 g of Dendrobium officinale, 200 g of American ginseng, 200 g of mannitol, 100 g of microcrystalline cellulose, 80 g of maltodextrin, and 7.5 g of magnesium stearate.

[0007] The present invention also provides a preparation method of the Cistanche deserticola and Dendrobium officinale tablet, including the following steps: S1. Weigh 500 g of Cistanche deserticola, 300 g of Dendrobium officinale, and 200 g of American ginseng, decoct with water for 2 hours, and then pour out the decoction for standby; S2. Re-extract the herbs that have been decocted once by adding water again and decoct for 1.5 hours, then pour out the decoction for later use. S3. Combine the above two portions of decoctions, filter them, and centrifuge. S4. Concentrate the centrifuged liquid to a thick paste with a relative density of 1.2 - 1.3 and a temperature of 70 °C. S5. Add 80 g of maltodextrin, 200 g of mannitol, 100 g of microcrystalline cellulose, and 7.5 g of magnesium stearate to make tablets, and perform inner packaging at 5 g per bag. At this time, the prepared Cistanche deserticola and Dendrobium officinale tablets are completed.

[0008] The Cistanche deserticola and Dendrobium officinale tablets provided by the present invention use Cistanche deserticola, Dendrobium officinale, and American ginseng as the main drugs, and maltodextrin, mannitol, microcrystalline cellulose, and magnesium stearate as excipients. Specifically as follows: Cistanche deserticola: It tastes sweet and salty, and is warm in nature; it has the effects of tonifying the kidney yang, benefiting essence and blood, and moistening the intestines for defecation. It is commonly used to treat diseases such as insufficient kidney yang, deficiency of essence and blood, impotence and infertility, soreness and weakness of the waist and knees, weakness of bones and muscles, and intestinal dryness and constipation.

[0009] Dendrobium officinale: It tastes sweet and is slightly cold in nature; it can benefit the stomach and promote the production of body fluid, nourish yin and clear heat. It can be used for conditions such as injury to body fluid caused by febrile diseases, dry mouth and polydipsia, deficiency of stomach yin, anorexia with nausea, lingering low-grade fever after illness, hyperactivity of fire due to yin deficiency, steaming bone fever, unclear vision, and weakness of bones and muscles.

[0010] American ginseng: It tastes sweet and slightly bitter, and is cool in nature; it has the functions of replenishing qi and nourishing yin, clearing heat and promoting the production of body fluid. It is used for qi deficiency with yin deficiency, deficiency heat and fatigue, cough with phlegm and blood, internal heat and thirst, dry mouth and throat, etc.

[0011] Maltodextrin: It can increase the consistency of the concentrated liquid, assist in granulation or tablet forming; as a filler, it can adjust the weight and density of the product to ensure uniform dosage per tablet; it can improve the taste of the product, making the taste more delicate after the tablet dissolves.

[0012] Mannitol: Mannitol has a cool sweet taste, with a sweetness of 0.5 - 0.7 times that of sucrose. It can be used to mask the bitter taste or other unpleasant odors of drugs, improve the taste of tablets, and make it easier for patients to accept; as a diluent, it can dilute the active ingredients of drugs to an appropriate concentration, facilitating accurate control of the dosage per administration, and also helps to improve the fluidity and compressibility of tablets, making the tablets more uniform during packaging; Mannitol has good stability, which can improve the stability of the product during storage to a certain extent, preventing the degradation or deterioration of active ingredients; in addition, it can reduce the hygroscopicity of tablets, avoiding caking and deterioration of tablets due to moisture absorption.

[0013] Microcrystalline cellulose: It acts as a diluent to increase the volume of the material and make the tablets reach the target weight; it has good disintegration properties, which can accelerate the disintegration of tablets in the gastrointestinal tract and promote the dissolution of active ingredients; it has good compressibility, enhancing the adhesiveness of the material and facilitating tablet forming, ensuring hardness and toughness.

[0014] Magnesium stearate: It plays a lubricating role during tablet preparation, reducing the friction between materials and equipment, preventing sticking to the punch and chipping; it has an anti-sticking effect, avoiding the adhesion of materials to the punch die and ensuring a smooth appearance of the tablets; it can also improve the fluidity of materials, making the weight difference of tablets smaller and the quality more stable.

[0015] The beneficial effects of the present invention are as follows: 1. In terms of the formula, Cistanche deserticola, Dendrobium officinale, and American ginseng are scientifically combined. The synergistic effects of warming and tonifying the kidney yang, nourishing yin and clearing heat, and replenishing qi and promoting fluid production can effectively regulate the balance of yin and yang in the body, nourish qi and blood, and enhance immunity. It is especially suitable for middle-aged and elderly people, precisely addressing the discomforts caused by various deficiencies, providing an efficient conditioning plan for sub-healthy people, and being suitable for people with high blood sugar.

[0016] 2. In terms of the preparation process, two decoctions fully release the active ingredients of the medicinal materials, and the filtration, centrifugation, and concentration steps ensure the maximization of the medicinal effects. Four types of excipients, maltodextrin, mannitol, microcrystalline cellulose, and magnesium stearate, each perform their own functions and work synergistically. Maltodextrin assists in forming and adjusting the dosage, mannitol improves the taste and stabilizes the quality, microcrystalline cellulose promotes disintegration and ensures formation, and magnesium stearate optimizes the tablet preparation process and improves the appearance and weight uniformity. This makes the tablets not only convenient to take with a good oral experience but also have good stability and disintegration properties. They are not prone to moisture absorption and deterioration during storage and transportation, disintegrate and dissolve rapidly, and the active ingredients are more fully absorbed, bringing a safe, efficient, and comfortable health care experience to consumers. Specific Embodiments

[0017] The following further describes the specific embodiments of the present invention in detail in conjunction with examples. The following examples are used to illustrate the present invention but not to limit the scope of the present invention.

[0018] The technical solutions described in the present invention are all conventional solutions in the art unless otherwise specified; the reagents or materials are all from commercial channels unless otherwise specified.

[0019] The present invention provides a Cistanche deserticola and Dendrobium officinale tablet, which is made from the following raw materials in parts by weight: 500 g of Cistanche deserticola, 300 g of Dendrobium officinale, 200 g of American ginseng, 200 g of mannitol, 100 g of microcrystalline cellulose, 80 g of maltodextrin, and 7.5 g of magnesium stearate. Example

[0020] The Cistanche deserticola and Dendrobium officinale tablet is composed of the following raw materials in parts by weight: 500 g of Cistanche deserticola, 300 g of Dendrobium officinale, 200 g of American ginseng, 200 g of mannitol, 100 g of microcrystalline cellulose, 80 g of maltodextrin, and 7.5 g of magnesium stearate.

[0021] The preparation method is as follows: S1. Weigh 500 g of Cistanche deserticola, 300 g of Dendrobium officinale, and 200 g of American ginseng, decoct them in water for 2 hours, then pour out the decoction and set it aside for later use. S2. Add water to the herbs that have been decocted once and decoct them for another 1.5 hours, then pour out the decoction and set it aside for later use. S3. Combine the above two portions of decoctions, filter them, and centrifuge. S4. Concentrate the centrifuged liquid into a thick paste with a relative density of 1.2 - 1.3 and a temperature of 70 °C. S5. Add 80 g of maltodextrin, 200 g of mannitol, 100 g of microcrystalline cellulose, and 7.5 g of magnesium stearate to make tablets, and press the tablets at 0.85 g / tablet. At this time, the Cistanche deserticola and Dendrobium officinale tablets are made.

[0022] Dosage method: Take it with warm water, 3 tablets each time, 2 times a day.

[0023] The technical features of the above-described embodiments can be combined arbitrarily. For the sake of brevity of description, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, it should be considered as the scope described in this specification.

[0024] The above-described embodiments merely represent several implementation manners of the present invention. The description is relatively specific and detailed, but it should not be construed as a limitation on the scope of the invention patent. It should be noted that for those of ordinary skill in the art, without departing from the concept of the present invention, several modifications and improvements can still be made, and these all belong to the protection scope of the present invention. Therefore, the protection scope of the present invention patent shall be subject to the appended claims.

Claims

1. A Cistanche deserticola and Dendrobium officinale tablet, characterized in that, The prepared Cistanche deserticola and Dendrobium officinale tablets are made from the following raw materials by weight: 500 g of Cistanche deserticola, 300 g of Dendrobium officinale, 200 g of American ginseng, 200 g of mannitol, 100 g of microcrystalline cellulose, 80 g of maltodextrin, and 7.5 g of magnesium stearate.

2. The preparation method of the cistanche deserticola and dendrobium officinale tablets according to claim 1, wherein It includes the following steps: S1. Weigh 500 g of Cistanche deserticola, 300 g of Dendrobium officinale, and 200 g of American ginseng, decoct them in water for 2 hours, then pour out the decoction and set it aside for later use. S2. Add water to the herbs that have been decocted once and decoct them for another 1.5 hours, then pour out the decoction and set it aside for later use. S3. Combine the above two portions of decoctions, filter them, and then centrifuge. S4. Concentrate the centrifuged liquid into a thick paste with a relative density of 1.2 - 1.3 at a temperature of 70 °C. S5. Add 200 g of mannitol, 100 g of microcrystalline cellulose, 80 g of maltodextrin, and 7.5 g of magnesium stearate to make tablets, and press the tablets at 0.85 g / tablet. At this time, the Cistanche deserticola and Dendrobium officinale tablets are completed.