Traditional Chinese medicine patch for conditioning yang-deficiency constitution as well as preparation method and application of traditional Chinese medicine patch

Abstract

The invention discloses a traditional Chinese medicine patch for conditioning yang-deficiency constitution and a preparation method and application thereof.The traditional Chinese medicine patch is prepared from ginger, safflower carthamus, folium artemisiae argyi, cassia twig and other traditional Chinese medicinal materials with the yang warming and cold dispelling effects according to a specific proportion through the fine processes of cleaning, drying, grinding, mixing, packaging and the like. During use, 2-6 patches are applied to the corresponding acupuncture points every day, the patch is applied to the corresponding acupuncture points for about 6 hours every time, and a treatment course lasts for 5-7 days. Clinical cases show that the traditional Chinese medicine composition has a remarkable improvement effect on symptoms caused by yang-deficiency constitution, such as cold shanks, sensation of chill, liking hot drinks, discomfort caused by eating cold food and the like. Compared with a traditional conditioning mode, the traditional Chinese medicine patch has the advantages of being convenient to use, rapid in effect, high in safety, good in compliance and the like, an innovative and effective conditioning scheme is provided for the crowd with the yang-deficiency constitution, and the traditional Chinese medicine patch has wide application prospects.

Description

Technical Field

[0001] The present invention relates to the technical field of conditioning yang-deficiency constitution. Specifically, it particularly relates to a traditional Chinese medicine patch for conditioning yang-deficiency constitution, its preparation method and application. Background Art

[0002] In the traditional medical system, the theory of constitution occupies an important position, and yang-deficiency constitution is a common type of biased constitution. According to the survey data of traditional Chinese medicine constitutions in some regions of China, the proportion of yang-deficiency constitution in the population is about 15%-20%. Those with yang-deficiency constitution have insufficient yang qi, and the body fails to be warmed, often showing a series of symptoms such as soft and flabby muscles, usually fearing cold, cold hands and feet, preferring hot food, listlessness, etc. Their personalities are mostly quiet and introverted. And due to the deficiency of yang qi, the body resistance decreases, and they are prone to diseases such as phlegm retention, swelling, diarrhea, etc. When being affected by external pathogens, they are also likely to transform into cold syndromes. Such people often tolerate summer but not winter and have weak resistance to wind, cold, and damp pathogens.

[0003] Currently, there are many methods for conditioning yang-deficiency constitution, but most of them have certain limitations. In terms of drug conditioning, although oral traditional Chinese medicine decoctions can condition the body as a whole, they need to be decocted for a long time and have a bitter taste. Many patients, especially children and the elderly, have poor compliance and are difficult to take them for a long time. Although patent medicines are convenient to take, their ingredients are fixed, it is difficult to flexibly adjust the formula according to individual differences, and some patent medicines may have adverse reactions such as gastrointestinal irritation. Among non-drug therapies, although moxibustion therapy can effectively warm yang and dispel cold, the operation process requires professional guidance, there is a risk of scalding, and the smoky smell is strong, so the usage scenarios are limited. Cupping therapy mainly focuses on dredging the meridians, dispelling cold and dampness, and its overall conditioning effect on yang-deficiency constitution is relatively single.

[0004] Most of the existing external patch products on the market are for single symptoms or diseases, such as joint pain, dysmenorrhea, etc. There are few patches specifically for comprehensively conditioning yang-deficiency constitution. And these patches may not be precise enough in formula and cannot effectively comprehensively condition various symptoms of yang-deficiency constitution. At the same time, some patches have deficiencies in the production process and material selection, which may lead to slow drug release, poor absorption effect, or adverse reactions such as skin allergies. Therefore, developing a safe, effective, convenient-to-use traditional Chinese medicine patch that can precisely condition yang-deficiency constitution has important practical significance for meeting the health needs of the vast number of people with yang-deficiency constitution. Summary of the Invention

[0005] The purpose of the present invention is to solve the disadvantages existing in the prior art, and to propose a traditional Chinese medicine patch for conditioning yang-deficiency constitution, which is composed of the following drugs in weight ratios: 6g of ginger, 7g of safflower, 6g of mugwort leaf, 6g of cassia twig, 6g of fennel, 7g of epimedium, 3g of cinnamon, 5g of chuanxiong, 3g of evodia rutaecarpa, 6g of clove.

[0006] Preferably, the ginger is fresh ginger, and its active ingredients such as volatile oil and gingerol help to exert the efficacy of relieving exterior syndrome and dispelling cold.

[0007] Preferably, the cinnamon is high-quality cinnamon, which has a relatively high content of cinnamaldehyde and can effectively play the role of promoting fire to eliminate yin and greatly tonifying yang qi.

[0008] A method for making a traditional Chinese medicine patch for conditioning yang-deficiency constitution includes the following steps: S1, Raw material pretreatment: Wash the ginger, dry it and cut it into thin slices; Remove impurities from safflower, mugwort leaf, cassia twig, fennel, epimedium, cinnamon, chuanxiong, evodia rutaecarpa, and cloves to ensure the purity of the raw materials; S2, Drying treatment: Place the pretreated raw materials in a drying equipment and dry them at a temperature of 40-50°C for 5-8 hours to make the moisture content of the raw materials lower than 8%, which is convenient for subsequent grinding; S3, Primary grinding: Put the dried raw materials into a common grinder for primary grinding until the particle size is 80-100 mesh; S4, Fine grinding: Transfer the medicated powder after primary grinding to an ultrafine grinder for further grinding until the particle size is 200-300 mesh to increase the surface area of the drug and improve the release rate of active ingredients; S5, Mixing and stirring: Pour the medicated powders of each flavor after fine grinding into a mixing and stirring machine and stir at a speed of 100-150 revolutions per minute for 15-20 minutes to ensure that the medicated powders are fully and evenly mixed; S6, Sealing: Put the evenly mixed medicated powder into a non-woven fabric bag with good air permeability and meeting the hygiene standards for sealed packaging to make a yang-deficiency patch.

[0009] Preferably, the drying equipment in the drying treatment process of step S2 adopts a vacuum drying oven, and by controlling the vacuum degree at 0.05-0.08 MPa, the drying speed is accelerated and the active ingredients of the drug are better retained.

[0010] Preferably, during the primary grinding and fine grinding processes in step S3 and step S4, the grinding equipment needs to be intermittently cooled to prevent the loss of drug components due to heat generated during grinding. Each cooling time is 5-10 minutes, and the interval grinding time is 20-30 minutes.

[0011] A method for using a traditional Chinese medicine patch for conditioning yang-deficiency constitution is to apply 2-6 patches per day, and apply to the corresponding acupoints for about 6 hours each time. Preferably, the corresponding acupoints include Shenque acupoint, Guanyuan acupoint, and Qihai acupoint, which are acupoints with the effect of warming yang after application.

[0012] Application of a traditional Chinese medicine patch for conditioning yang-deficiency constitution in the treatment of yang-deficiency related diseases. The traditional Chinese medicine patch is mainly applied in yang-deficiency related diseases, and the yang-deficiency related diseases include cold uterus infertility, dysmenorrhea, hair loss, osteoporosis, arthralgia syndrome, Alzheimer's disease, tumor, coronary heart disease.

[0013] Preferably, when preparing a drug for treating arthralgia syndrome, combined with appropriate rehabilitation exercises, the traditional Chinese medicine patch can better exert the effects of warming the meridians and dispelling cold to relieve pain.

[0014] Among the above raw materials: Ginger is pungent and slightly warm in nature, and can relieve exterior syndrome and dispel cold. Cinnamon is pungent, sweet and extremely hot, with pure yang and warm dispersion. It can replenish fire to eliminate yin and greatly tonify yang qi, and is the key medicine for treating decline of kidney yang. Evodia rutaecarpa is pungent, dispersing, bitter and purging, warm in nature and promoting circulation. It is good at dispersing the cold of Jueyin meridian and is the key medicine for treating various pains caused by cold congealing in the liver meridian. Fennel can warm the kidney and liver, promote qi flow and relieve pain, and is the key medicine for treating cold congealing and qi stagnation. Clove is pungent, warm and fragrant in qi. It is good at warming the middle-jiao and strengthening the stomach, and is the key medicine for treating vomiting due to stomach cold. Mugwort leaf has a fragrant smell and is pungent in taste. It is warm and can dispel cold, warm qi and blood, and warm the meridians. It is the key medicine for warming the meridian and regulating blood. Safflower is pungent, dispersing, warm and promoting circulation. It specifically enters the blood aspect. Chuanxiong is pungent, dispersing, warm and promoting circulation. It can activate blood circulation and remove stasis to dredge the meridians, and is good at dispersing wind-cold-damp pathogens in the exterior. Epimedium is warm and dry in nature, and is good at warming and tonifying the fire of the kidney yang. Therefore, it can promote yang, and is the key medicine for warming the kidney and strengthening yang to treat impotence. Ramulus Cinnamomi is pungent, dispersing, warm and promoting circulation. It can dredge the cold stagnation in the meridians and relieve pain.

[0015] Compared with the existing technology, the beneficial effects of the present invention are: 1. Significant conditioning effect: The traditional Chinese medicine patch has a delicate compatibility of drugs. The synergistic effect of multiple herbs such as ginger, cinnamon, evodia rutaecarpa, etc. can quickly supplement the yang qi of the human body and effectively improve the yang-deficiency constitution. In the treatment of cold uterus infertility and dysmenorrhea, it can warm and dredge the uterine cavity, dispel cold and relieve pain, regulate the function of the female reproductive system, improve the pregnancy rate, and relieve menstrual pain. For hair loss and osteoporosis, by warming and tonifying the kidney yang, promoting qi and blood circulation, providing sufficient nutrition for hair and bones, and improving the symptoms. For arthralgia syndrome (rheumatoid arthritis), it can disperse wind-cold-damp pathogens, dredge the collaterals and relieve pain, reduce joint pain and swelling, and improve joint mobility. For diseases such as Alzheimer's disease, tumor, coronary heart disease, etc., by warming yang to improve the qi and blood circulation and visceral functions of the body, it can assist in improving the quality of life of patients. 2. Green and natural, with high safety: The medicinal materials such as ginger, safflower, and mugwort used in the traditional Chinese medicine patch are all natural Chinese medicinal materials. While playing a therapeutic role, compared with chemically synthesized drugs, they have fewer adverse reactions and less side effects on the human body. Long-term use is not likely to cause damage to liver and kidney functions, etc. It is especially suitable for yang-deficiency patients with relatively weak constitutions who are not suitable for strong drug stimulation. 3. Scientific production process, full play of medicinal effects: The production method is carefully designed. From raw material pretreatment, drying, to fine grinding, mixing, and sealing, every step is strictly controlled. For example, drying at a low temperature of 40 - 50 °C for 5 - 8 hours can not only remove moisture for easy grinding but also retain the active ingredients of the medicinal materials to the greatest extent. After the first grinding, it is further ultra-finely ground to 200 - 300 meshes, greatly increasing the surface area of the drug, making the active ingredients more easily released, improving the drug utilization rate, and thus enhancing the conditioning effect. 4. Convenient to use, high compliance: The traditional Chinese medicine patch adopts the external application method, 2 - 6 patches per day, and each patch is applied to the corresponding acupoints for about 6 hours. The operation is simple, and patients can use it by themselves without the need for complex medical equipment and professional guidance. Compared with oral medications, it avoids the irritation of drugs to the gastrointestinal tract and also eliminates the need for patients to take medications frequently, improving the patient's medication compliance and being more suitable for long-term conditioning use. 5. Wide range of applications, economical and practical: This traditional Chinese medicine patch can be used for the treatment and conditioning of various yang-deficiency related diseases, covering multiple medical fields, with a wide range of applications. At the same time, its production cost is relatively low, and the raw materials are rich in sources. While providing effective treatment for patients, it reduces the economic burden on patients, has a high cost performance, and is conducive to wide promotion and application in clinical practice and daily life. Brief Description of the Drawings

[0016] Figure 1 It is a schematic diagram of the production process of a traditional Chinese medicine patch for conditioning yang-deficiency constitution proposed by the present invention. Detailed Embodiments

[0017] Next, the technical solutions in the embodiments of the present invention will be clearly and completely described in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all of the embodiments.

[0018] This embodiment provides a traditional Chinese medicine patch for conditioning yang-deficiency constitution, which is composed of the following drugs in weight ratios: 6 g of ginger, 7 g of safflower, 6 g of mugwort, 6 g of cinnamon twig, 6 g of fennel, 7 g of epimedium, 3 g of cinnamon, 5 g of chuanxiong, 3 g of evodia rutaecarpa, and 6 g of clove.

[0019] Furthermore, the ginger is fresh ginger, and its active ingredients such as volatile oil and gingerol help to play the role of relieving exterior cold and dispelling cold.

[0020] Furthermore, the cinnamon is high-quality cinnamon with a high content of cinnamaldehyde, which can effectively play the role of tonifying yang and dispelling yin and greatly tonifying yang qi.

[0021] A method for making a traditional Chinese medicine patch for conditioning yang-deficient constitution, comprising the following steps: S1, raw material pretreatment: Wash the ginger, dry it, and then cut it into thin slices; Remove impurities from safflower, mugwort leaf, cassia twig, fennel, epimedium, cinnamon, chuanxiong rhizome, evodia fruit, and clove to ensure the purity of the raw materials. Regarding step S1, further, it comprises the following steps: ① Medicinal material selection: Strictly select 6g of ginger, 7g of safflower, 6g of mugwort leaf, 6g of cassia twig, 6g of fennel, 7g of epimedium, 3g of cinnamon, 5g of chuanxiong rhizome, 3g of evodia fruit, and 6g of clove according to the formula. Ensure that all medicinal materials are of good quality, free from mildew and impurities. For example, select fresh and non-rotten old ginger for ginger, which has a strong pungent taste and a high content of effective ingredients such as volatile oil; Select high-quality cinnamon with thick skin, high oiliness, and strong aroma for cinnamon to ensure an adequate amount of key components such as cinnamaldehyde to guarantee the medicinal effect. ② Cleaning and pretreatment: Wash the ginger and dry it, then cut it into thin slices with a thickness of about 2-3 mm to increase the drying surface area and accelerate the drying speed. Screen the medicinal materials such as safflower, mugwort leaf, cassia twig, fennel, epimedium, cinnamon, chuanxiong rhizome, evodia fruit, and clove to remove residual sediment, branches and leaves and other impurities.

[0022] S2, drying treatment: Place the pretreated raw materials in a drying equipment and dry them at a temperature of 40-50°C for 5-8 hours to make the moisture content of the raw materials lower than 8%, which is convenient for subsequent grinding. Regarding step S2, further, it comprises the following steps: ① Equipment selection: Use a vacuum drying oven for drying treatment, set the vacuum degree to 0.05-0.08 MPa, and control the temperature at 40-50°C. This condition can avoid the destruction of thermosensitive components of the medicinal materials by high temperature and accelerate the evaporation of moisture at the same time. ② Drying time: Set the drying time to 5-8 hours, and regularly observe the drying degree of the medicinal materials during this period. When the moisture content of the medicinal materials is lower than 8%, it is considered that the drying is up to standard. By precisely controlling the drying conditions, ensure that the effective components of the medicinal materials are retained to the greatest extent.

[0023] S3, Primary grinding: Put the dried raw materials into a common grinding machine for primary grinding until the particle size reaches 80 - 100 mesh; further, in this step, put the dried medicinal materials into a common grinding machine for primary grinding; set the rotation speed of the grinding machine at 150 - 200 revolutions per minute, and control the grinding time within 10 - 15 minutes to preliminarily crush the medicinal materials to a particle size of 80 - 100 mesh. During the grinding process, intermittently cool the grinding machine for 5 - 10 minutes every 20 - 30 minutes to prevent the loss of medicinal material components due to heat generated during grinding.

[0024] S4, Fine grinding: Transfer the powder after primary grinding to an ultrafine grinding machine for further grinding until the particle size reaches 200 - 300 mesh to increase the surface area of the drug and improve the release rate of active ingredients; more specifically, in this step, transfer the powder after primary grinding to an ultrafine grinding machine. Set the frequency of the ultrafine grinding machine at 20 - 30 Hz and the grinding time at 20 - 30 minutes to further grind the powder to a particle size of 200 - 300 mesh. Ultrafine grinding can greatly increase the surface area of the drug, which is beneficial to the release of active ingredients.

[0025] S5, Mixing and stirring: Pour the fine - ground medicinal powders into a mixing and stirring machine and stir at a speed of 100 - 150 revolutions per minute for 15 - 20 minutes to ensure that the medicinal powders are fully and evenly mixed, thereby making the efficacy of each traditional Chinese medicine patch stable and consistent; S6, Sealing and packaging: Put the evenly - mixed medicinal powder into a non - woven fabric bag with good air permeability and meeting the hygiene standards for sealed packaging to make the Yang - deficiency patch; Regarding step S6, further, it includes the following steps: ① Selection of packaging materials: Select a non - woven fabric bag with good air permeability and meeting the hygiene standards as the packaging material. The gram weight of the non - woven fabric bag is 30 - 40 grams per square meter, which can not only ensure a certain gas exchange between the medicinal powder and the outside world to maintain the stability of the medicinal powder, but also prevent the leakage of the medicinal powder.

[0026] ② Sealing operation: Use an automatic quantitative packaging machine to put the evenly - mixed medicinal powder into the non - woven fabric bag according to the standard of 15 grams per bag of medicinal powder, and then conduct sealed packaging to make the final Yang - deficiency patch product. After packaging, conduct quality inspection on the product to ensure that the packaging is complete and undamaged, and the weight of the medicinal powder meets the standard.

[0027] Further, in the drying process of step S2, the drying equipment uses a vacuum drying oven. By controlling the vacuum degree at 0.05 - 0.08 MPa, the drying speed is accelerated and the active ingredients of the drug are better retained.

[0028] Furthermore, during the initial grinding and fine grinding process in step S3 and step S4, the grinding equipment needs to be intermittently cooled to prevent the loss of drug components due to heat generated by grinding. The cooling time for each time is 5-10 minutes, and the interval grinding time is 20-30 minutes.

[0029] A method for using a Chinese medicine patch for regulating yang deficiency constitution, applying 2 to 6 patches per day, and applying to corresponding acupuncture points for about 6 hours each time.

[0030] Furthermore, the corresponding acupoints include Shenque point, Guanyuan point, and Qihai point, which have the effect of warming yang after application.

[0031] When using it, you can refer to the following steps: 1. Preparation before use Clean the skin: Before applying the Chinese medicine patch, wash the skin of the area to be applied with warm water to ensure that the skin is clean, dry and free of dirt, oil and sweat. Use a soft towel to gently dry the skin to prevent the adhesion of the patch and the absorption of the drug from being affected by unclean skin.

[0032] Determine the acupoints: According to the theory of traditional Chinese medicine, for people with yang deficiency, the common acupoints for application include Shenque (located in the center of the navel), Guanyuan (located in the lower abdomen, on the anterior midline, 3 inches below the navel), Qihai (located in the lower abdomen, on the anterior midline, 1.5 inches below the navel), Mingmen (located in the waist, on the posterior midline, in the depression below the spinous process of the second lumbar vertebra), etc. You can also use the human acupoint map or under the guidance of a traditional Chinese medicine practitioner to accurately find these acupoints to ensure that the patch can act on the precise location and exert the best therapeutic effect.

[0033] 2. Application Operation Selection and preparation of the patch: According to your physical condition, the severity of your symptoms, and the instructions for use, choose to apply 2-6 patches per day. For example, people with mild symptoms and first-time users can start with 2-3 patches per day; users with more obvious symptoms or who have adapted for a period of time can gradually increase to 4-6 patches per day. Open the patch package and carefully remove the patch to avoid spilling the powder.

[0034] Application process: Gently peel off the release paper of the patch, accurately align the side with the medicine powder to the determined acupuncture point, and then gently press the edge of the patch to make it fit the skin tightly. Make sure there are no bubbles or wrinkles between the patch and the skin to ensure that the drug can fully contact the skin and promote absorption.

[0035] 3. Application time control The application time for each application is controlled at about 6 hours. During the application, closely monitor the skin reaction. If discomfort symptoms such as skin itching, tingling, or redness occur during the application, immediately remove the medicated patch and wash the application area with clean water. If the symptoms do not relieve or worsen, seek medical attention in a timely manner. If there is no discomfort after 6 hours of application, the medicated patch can be removed on time. When removing, gently peel it off along the skin direction to avoid damaging the skin due to excessive force.

[0036] The traditional Chinese medicine patch for conditioning yang deficiency constitution described in the above embodiments is mainly applied to yang deficiency-related diseases; the yang deficiency-related diseases include infertility due to cold uterus, dysmenorrhea, hair loss, osteoporosis, arthralgia syndrome, Alzheimer's disease, tumors, and coronary heart disease.

[0037] Furthermore, when preparing drugs for treating arthralgia syndrome, combined with appropriate rehabilitation exercises, the effects of warming and dredging meridians and dispelling cold and relieving pain of the traditional Chinese medicine patch can be better exerted.

[0038] Clinical cases and application courses of some yang deficiency patches are not provided for all diseases: The main symptoms of yang deficiency constitution mainly include: loose and flabby muscles. Usually afraid of cold, hands and feet are not warm, like hot food, listless, pale, plump and tender tongue, deep and slow pulse. The personality is mostly quiet and introverted. Prone to diseases such as phlegm retention, swelling, and diarrhea, and is prone to cold transformation when infected. Tolerant to summer but not winter, susceptible to wind, cold, and damp pathogens.

[0039] Case 1: Yang deficiency constitution: Chen Modan, female, 35 years old, from Heze City, Shandong Province. The physical examination shows a tendency to yang deficiency, and the symptom is that the calves often feel cold. In October this year, she began to use the yang deficiency medicated patch, 4 patches per day. After the first day of application, on the second day, she reported that the symptom of cold calves had improved. Then she continued to apply for 4 consecutive days. She reported that her calves were no longer cold. Three days later, during the follow-up visit, she reported that her calves no longer felt cold. Treatment method: warming yang and dispelling cold. Use the above formula for conditioning for 5 days as a course of treatment. Application method: 4 patches per day, apply to the corresponding acupoints. Each application lasts for 6 hours. Dietary taboos: avoid alcohol and spicy and stimulating foods, and need to have a light diet.

[0040] Case 2: Yang deficiency conditioning: Gao Mobin, male, 54 years old, from Heze City, Shandong Province. In September, the physical examination showed a tendency to yang deficiency. Usually, the symptoms are fear of cold and preference for hot drinks, and discomfort in the stomach after eating cold food. On September 30 this year, he began to use the yang deficiency patch, 4 patches per day, applied to the corresponding acupoints. On the third day of application, after taking cold food, his stomach did not feel uncomfortable. Then he continued to apply for 2 consecutive days. After 5 days of application, the yang deficiency symptoms were further improved. He reported that he was no longer afraid of cold when taking things out of the refrigerator as before. Treatment method: warming yang and dispelling cold. Use the above formula for conditioning for 5 days as a course of treatment. Application method: 4 patches per day, each application lasts for 6 hours. Dietary taboos: avoid alcohol and spicy and stimulating foods, and need to have a light diet.

[0041] The yang deficiency patch of the present invention, its preparation method and usage method show significant beneficial effects in many aspects in clinical applications: 1. Significant and rapid conditioning effect: From clinical cases, the Yang-deficiency patch has an immediate effect on conditioning the Yang-deficiency constitution. Taking Chen Dan as an example, after only one day of application, the symptom of coldness in the calves was improved. After continuous application for 5 days, during the follow-up three days later, the symptom did not reappear; after Gao Weibin applied the patch for three days, the discomfort in the stomach after eating cold food disappeared, and the sensitivity to cold decreased significantly after 5 days. This shows that the Yang-deficiency patch can act quickly on the human body, effectively relieve Yang-deficiency symptoms, improve the quality of life of patients, and truly solve the problems of people with Yang-deficiency constitution.

[0042] 2. Precise targeting of Yang-deficiency constitution symptoms: People with Yang-deficiency constitution generally have symptoms such as fear of cold, cold hands and feet, preference for hot food, and susceptibility to cold syndromes. The formula of the Yang-deficiency patch precisely targets these problems and effectively regulates the balance of yin and yang in the human body through the mechanism of warming yang and dispelling cold. It can not only improve the sense of coldness in the body, but also has an obvious conditioning effect on problems such as digestive discomfort caused by Yang-deficiency, comprehensively improving various discomfort symptoms brought about by Yang-deficiency constitution.

[0043] 3. Short treatment course and convenient use: The Yang-deficiency patch takes 5 days as a treatment course, with 4 patches applied every day for 6 hours each time. The operation is simple, and patients can complete the application by themselves without the assistance of professional medical staff. Compared with some conditioning methods that require long-term medication or complex treatment means, the Yang-deficiency patch has a short treatment course and is easy to use, greatly improving the compliance of patients and being more conducive to continuous treatment and recovery.

[0044] 4. High safety and few side effects: The Yang-deficiency patch is made of natural traditional Chinese medicines and has few side effects compared with some chemically synthesized drugs. In clinical cases, no adverse reactions have occurred due to the use of the Yang-deficiency patch. For people with Yang-deficiency who are relatively weak in constitution and have poor drug tolerance, it is a safe and reliable conditioning method and can be used for a long time without worrying about causing additional burden to the body.

[0045] 5. Combining diet guidance to strengthen the conditioning effect: While using the Yang-deficiency patch, combined with diet guidance of avoiding alcohol, spicy and stimulating foods, and having a light diet, the conditioning effect can be further strengthened. A reasonable diet helps the body better absorb the effective components of the drug, reduces the adverse effects of diet factors on Yang-deficiency symptoms, and forms a synergistic effect with the treatment of the Yang-deficiency patch, promoting the improvement of the patient's physical condition from multiple aspects.

[0046] 6. Wide range of applicable populations: Whether it is a 35-year-old woman or a 54-year-old man, the Yang-deficiency patch shows good conditioning effects, indicating that its applicable populations are wide and not restricted by age and gender. This provides a general and effective conditioning method for the vast number of people with Yang-deficiency constitution and has broad application prospects and promotion value.

[0047] In the above specific embodiments, the objectives, technical solutions, and beneficial effects of the present invention have been further described in detail. It should be understood that the above are only specific embodiments of the present invention, but the protection scope of the present invention is not limited thereto. Any person skilled in the art within the technical scope disclosed by the present invention, according to the technical solution and inventive concept of the present invention, making equivalent substitutions or changes should be covered within the protection scope of the present invention.

[0048] In addition, in the description of the present invention, it should be understood that the terms indicating the orientation or positional relationship are based on the orientation or positional relationship shown in the drawings, and are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus cannot be understood as a limitation of the present invention. Furthermore, in the present invention, unless otherwise clearly defined and limited, the terms "installed", "connected", "connected", "fixed", etc. should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or integrated; it can be a mechanical connection or an electrical connection; it can be directly connected or indirectly connected through an intermediate medium, and it can be the internal communication of two elements or the interaction relationship between two elements. For those of ordinary skill in the art, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

Claims

1. A traditional Chinese medicine patch for conditioning yang-deficiency constitution, characterized in that, It is composed of the following drugs in weight ratio: 6g of ginger, 7g of safflower, 6g of mugwort leaf, 6g of cassia twig, 6g of fennel, 7g of epimedium, 3g of cinnamon, 5g of chuanxiong rhizome, 3g of evodia fruit, and 6g of clove.

2. The traditional Chinese medicine patch for conditioning yang-deficiency constitution according to claim 1, wherein, The ginger is fresh ginger, and its active ingredients such as volatile oil and gingerol help to exert the effect of relieving exterior syndrome and dispelling cold.

3. The traditional Chinese medicine patch for conditioning yang-deficiency constitution according to claim 1, wherein The cinnamon is high-quality cinnamon, which has a high content of cinnamaldehyde and can effectively play the role of replenishing fire and dispelling yin, and greatly tonifying yang qi.

4. The manufacturing method of the traditional Chinese medicine patch for conditioning yang-deficiency constitution according to claim 1, characterized in that, It includes the following steps: S1, Raw material pretreatment: Wash the ginger, dry it and cut it into thin slices; Remove impurities from safflower, mugwort leaf, cassia twig, fennel, epimedium, cinnamon, chuanxiong rhizome, evodia fruit, and clove to ensure the purity of the raw materials. S2, Drying treatment: Place the pretreated raw materials in a drying equipment and dry them at a temperature of 40 - 50 °C for 5 - 8 hours to make the moisture content of the raw materials lower than 8%, which is convenient for subsequent grinding. S3, Primary grinding: Put the dried raw materials into a common grinder for primary grinding until the particle size reaches 80 - 100 mesh. S4, Fine grinding: Transfer the powder after primary grinding to an ultrafine grinder for further grinding until the particle size reaches 200 - 300 mesh to increase the surface area of the drug and improve the release rate of the active ingredients. S5, Mixing and stirring: Pour the powders of each drug after fine grinding into a mixing and stirring machine and stir at a speed of 100 - 150 revolutions per minute for 15 - 20 minutes to ensure that the powders are fully mixed evenly. S6, Sealing and packaging: Put the evenly mixed powder into a non-woven bag with good air permeability and meeting the hygienic standards for sealing and packaging to make the yang deficiency patch.

5. The method for preparing the traditional Chinese medicine patch for conditioning yang-deficiency constitution according to claim 4, wherein The drying equipment in the drying treatment process of step S2 adopts a vacuum drying oven. By controlling the vacuum degree at 0.05 - 0.08 MPa, the drying speed is accelerated and the active ingredients of the drug are better retained.

6. The manufacturing method of the traditional Chinese medicine patch for conditioning yang-deficiency constitution according to claim 4, characterized in that, In the process of primary grinding and fine grinding in step S3 and step S4, it is necessary to cool the grinding equipment intermittently to prevent the loss of drug components caused by heat generated during grinding. Each cooling time is 5 - 10 minutes, and the interval grinding time is 20 - 30 minutes.

7. A method for using a traditional Chinese medicine patch for conditioning yang-deficiency constitution as described in claim 1, characterized in that, Apply 2 - 6 patches per day, and apply to the corresponding acupoints for about 6 hours each time.

8. The usage method of the traditional Chinese medicine patch for conditioning yang-deficient constitution according to claim 7, characterized in that, The corresponding acupoints include Shenque acupoint, Guanyuan acupoint, and Qihai acupoint, which are acupoints with the effect of warming yang after application.

9. Use of a traditional Chinese medicine patch for conditioning yang-deficiency constitution as described in claim 1 in the treatment of yang-deficiency related diseases, characterized in that, The traditional Chinese medicine patch is mainly applied to yang deficiency-related diseases; the yang deficiency-related diseases include cold uterus infertility, dysmenorrhea, hair loss, osteoporosis, arthralgia syndrome, Alzheimer's disease, tumor, and coronary heart disease.

10. Use of the traditional Chinese medicine patch for conditioning yang-deficiency constitution according to claim 9 in the treatment of yang-deficiency related diseases, characterized in that, When preparing drugs for treating arthralgia syndrome, combined with appropriate rehabilitation exercises, the traditional Chinese medicine patch can better play the effects of warming the meridians and dispelling cold and relieving pain.

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