Full-automatic dry biochemical analyzer and production process thereof

Abstract

The invention belongs to the technical field of biochemical analyzers, and provides a full-automatic dry-type biochemical analyzer and a production process thereof, the full-automatic dry-type biochemical analyzer comprises a rack device, a constant temperature control device, a light path module, a detection analysis assembly, a mechanical transmission system and a control module; the constant-temperature control device is used for implementing constant-temperature control; the light path module is used for providing a light source required by detection and analysis; the detection analysis assembly is used for carrying out biochemical analysis on the target specimen; the mechanical transmission system is used for driving and controlling the detection and analysis assembly to work; and the control module is used for managing and controlling the constant temperature control device, the light path module and the mechanical transmission system based on data acquisition of the constant temperature control device and the light path module. According to the invention, the reliability of an analysis result can be improved, the accuracy of a detection signal is ensured, biochemical analysis of a target sample can be rapidly and accurately completed, and the overall performance of the analyzer is improved.

Description

Technical Field

[0001] The present invention relates to the technical field of biochemical analyzers, and particularly to a fully automatic dry biochemical analyzer and its production process. Background Art

[0002] A biochemical analyzer is used to detect various biochemical indicators in blood and body fluid samples, such as blood glucose, liver function indicators, etc.; the temperature control device of traditional biochemical analyzers uses a Peltier element for temperature control, which has disadvantages such as poor temperature uniformity and easy aging of the heating sheet. Poor temperature uniformity will greatly affect the final test accuracy of the device;

[0003] The light source of traditional biochemical analyzers is a single halogen tungsten lamp light source, which has a relatively short lifespan, relatively large light decay, large heat generation and concentrated heat generation. A radiator and a fan are required to solve the heat dissipation problem. The light source has a large attenuation source in the later stage, and the heat dissipation is unstable, affecting the final test accuracy of the product; in addition, due to the short lifespan of the light source, the need to replace the light source during later use increases the consumable cost, labor cost and efficiency;

[0004] The optical path structure of traditional biochemical analyzers uses multi-channel beam splitting lenses. There is power consumption for light passing through each beam splitter, and at the light output part of the final optical path, the accumulated power consumption is extremely large. Due to the excessive power consumption of the light intensity in the last path, it cannot meet the test requirements of more light waves. Currently, there are at most eight different light waves. Due to the relatively few light waves, it ultimately affects the test accuracy of the product;

[0005] The mechanical transmission system of traditional biochemical analyzers has many components, complex structure, difficult maintenance, and complex manufacturing processes for key components;

[0006] The modularity of the production process of traditional biochemical analyzers is low, resulting in low assembly efficiency, complex calibration processes, and long test cycles.

[0007] Therefore, it is necessary to provide a fully automatic dry biochemical analyzer and its production process. Summary of the Invention

[0008] The present invention provides a fully automatic dry biochemical analyzer and its production process, which can improve the reliability of analysis results, ensure the accuracy of detection signals, can quickly and accurately complete the biochemical analysis of target specimens, and improve the overall performance of the analyzer.

[0009] The present invention provides a fully automatic dry biochemical analyzer, comprising: a frame device, a constant temperature control device, an optical path module, a detection and analysis component, a mechanical transmission system, and a control module; the constant temperature control device is used to implement constant temperature control, the optical path module is used to provide a light source required for detection and analysis; the detection and analysis component is used to perform biochemical analysis on a target specimen; the mechanical transmission system is used to drive and control the operation of the detection and analysis component; the control module is used to manage and control the constant temperature control device, the optical path module, and the mechanical transmission system based on data acquisition of the constant temperature control device and the optical path module.

[0010] Further, the frame device includes a base and an integrated bracket, and a plurality of silica gel shock pads are arranged at the four corners of the base.

[0011] Further, the constant temperature control device includes a temperature control unit, a heating element, and a temperature sensor; the temperature control unit includes a temperature control circuit and a circulation fan; the temperature control circuit is used to heat the heating element to increase the internal air temperature of the fully automatic dry biochemical analyzer; the circulation fan is used to make the internal air of the fully automatic dry biochemical analyzer flow; the temperature sensor is used to collect the internal air temperature of the fully automatic dry biochemical analyzer in real time and feedback the collected air temperature to the temperature control unit.

[0012] Further, the temperature control unit integrates an environmental temperature compensation algorithm and dynamically adjusts the parameters of the PID controller according to the internal air temperature of the fully automatic dry biochemical analyzer fed back by the temperature sensor.

[0013] Further, the optical path module includes a light source component and a photodetector; the light source component includes a light emitting device and a light receiving device; the light source component is an LED array, and the LED array adopts 12 or 16 independent LED light sources; each independent LED light source corresponds to an independent photoelectric detection channel; the photodetector is used to perform photoelectric signal conversion on the LED light source.

[0014] Further, the optical path module further includes an intelligent attenuation compensation unit; the intelligent attenuation compensation unit includes:

[0015] Based on a current sensor and a light intensity detector, respectively collect the driving current and output light intensity of each LED light source;

[0016] According to the driving current and output light intensity, based on the Arrhenius correction model, predict the lifespan of each LED light source to obtain the lifespan prediction result of the LED light source;

[0017] According to the lifespan prediction result of the LED light source, set a multi-level alarm strategy;

[0018] If the lifespan prediction value in the lifespan prediction result of the LED light source is less than the set lifespan threshold, dynamically adjust the driving current according to the real-time light attenuation rate and correct the generated temperature drift term.

[0019] Further, the mechanical transmission system includes a motor and a transmission component; the motor is used to provide power for the transmission component, and the transmission component is used to drive the operation of the control detection and analysis component.

[0020] Further, the control module includes a main control chip and a data acquisition component; the data acquisition component is used to collect the temperature data of the constant temperature control device, the light source intensity data of the optical path module, and the position positioning data of the transmission component; the main control chip controls the operation of the constant temperature control device, the optical path module, and the mechanical transmission system based on the analysis and processing results of the temperature data, the light source intensity data, and the position positioning data, and based on the dynamic compensation strategy.

[0021] The dynamic compensation strategy includes temperature drift compensation, optical path attenuation compensation, and mechanical error compensation; the temperature drift compensation is: when the temperature difference is greater than the set temperature threshold, adjust the rotation speed of the circulation fan; the optical path attenuation compensation is: according to the matching relationship curve between the LED current and the light intensity in the set photodetector, correct the detection signal of the photodetector in real time; the mechanical error compensation is: update the control parameters of the mechanical transmission system based on the position positioning data.

[0022] Further, the control module further includes an equipment health assessment unit, and the health assessment unit is used for:

[0023] Detect and obtain the equipment health assessment parameters of the fully automatic dry biochemical analyzer; the equipment health assessment parameters include the motor current ripple coefficient, the heating element resistance change rate, and the photodetector dark current value.

[0024] Detect and obtain the working environment parameters of the fully automatic dry biochemical analyzer; the working environment parameters include the ambient temperature and the ambient humidity.

[0025] Detect and obtain the working operation state data of the fully automatic dry biochemical analyzer; the working operation state data includes the cumulative operation duration and the average daily detection times.

[0026] Establish a component life degradation model based on the long short-term memory network.

[0027] Based on the equipment health assessment detection parameters, the working environment parameters, and the working operation state data, use the component life degradation model to predict the life of the fully automatic dry biochemical analyzer. If the predicted remaining life is less than the set first life threshold, trigger the execution of the self-repair strategy; if the predicted remaining life is less than the set second life threshold, issue a warning reminder; the self-repair strategy includes optical path attenuation compensation and mechanical transmission system backlash compensation; the optical path attenuation compensation includes performing reference optical path calibration; the mechanical transmission system backlash compensation includes compensation based on the mapping table of the set position and the compensation amount.

[0028] A production process of a fully automatic dry biochemical analyzer, comprising the following steps:

[0029] S1: Install the silica gel shock pad on the base, and then assemble the integrated bracket;

[0030] S2: Implement modular assembly, specifically including:

[0031] S201: Assemble the constant temperature module, install the heating element and the temperature sensor into the biochemical analysis and detection area set inside the integrated bracket, and connect them to the set temperature control unit;

[0032] S202: Assemble the optical path module, install the light source component and the photodetector in the biochemical analysis and detection area set inside the integrated bracket, and perform optical path calibration using a standard sample; The optical path calibration includes light source intensity calibration, wavelength accuracy calibration, and photodetector response linearity calibration;

[0033] S203: Install the detection and analysis component in the biochemical analysis and detection area configured inside the integrated bracket; Among them, the guide rail of the target sample tray bracket in the detection and analysis component is integrally printed and produced based on laser selective melting technology;

[0034] S204: Install the mechanical transmission system inside the integrated bracket, and perform motion accuracy testing and position positioning calibration;

[0035] S205: Install the control module inside the integrated bracket, and burn the control program;

[0036] S3: Conduct functional testing and performance verification on the fully automatic dry biochemical analyzer.

[0037] Compared with the prior art, the present invention has the following advantages and beneficial effects: Through a highly integrated module design, an efficient biochemical analysis process is achieved; the modules work together to ensure the accuracy and stability of the analysis results; the intelligent temperature control system of the constant temperature control device, combined with the ambient temperature compensation algorithm, can accurately control the internal temperature of the instrument, reduce the influence of temperature fluctuations on the analysis results, and improve the accuracy and repeatability of the analysis; the optical path module adopts an advanced liquid crystal tunable filter and multi-channel LED light source design, which not only improves the stability and flexibility of the light source, but also predicts and dynamically adjusts the light source life through the intelligent attenuation compensation unit, effectively extending the service life of the light source and reducing the maintenance cost; the mechanical transmission system adopts high-precision motors and transmission components to ensure the accurate positioning and stable operation of the detection and analysis components; the control module integrates powerful data processing and analysis functions, can real-time monitor and analyze various parameters of the instrument, and dynamically adjust the working state of the instrument according to the analysis results, realizing intelligent management and control. In addition, the equipment health assessment unit can comprehensively evaluate the health status of the instrument, predict the remaining life of the instrument, and provide strong support for the maintenance and upkeep of the instrument.

[0038] Other features and advantages of the present invention will be described in the following specification, and, in part, will be obvious from the specification, or will be learned by practicing the present invention. The objectives and other advantages of the present invention can be realized and obtained by the structure particularly pointed out in the written specification and the drawings.

[0039] The technical solutions of the present invention will be further described in detail below through the drawings and embodiments. BRIEF DESCRIPTION OF THE DRAWINGS

[0040] The drawings are used to provide a further understanding of the present invention, and constitute a part of the specification, and are used to explain the present invention together with the embodiments of the present invention, and do not constitute a limitation to the present invention. In the drawings:

[0041] Figure 1 is a schematic structural diagram of a fully automatic dry biochemical analyzer;

[0042] Figure 2 is a schematic structural diagram of the constant temperature control device;

[0043] Figure 3 is a schematic production process diagram of a fully automatic dry biochemical analyzer. DETAILED DESCRIPTION OF THE EMBODIMENTS

[0044] The following describes the preferred embodiments of the present invention with reference to the drawings. It should be understood that the preferred embodiments described herein are only used to illustrate and explain the present invention, and are not used to limit the present invention.

[0045] The present invention provides a fully automatic dry biochemical analyzer, asFigure 1 As shown, it includes:

[0046] A frame device, a constant temperature control device, an optical path module, a detection and analysis component, a mechanical transmission system, and a control module; the constant temperature control device is used to implement constant temperature control, and the optical path module is used to provide the light source required for detection and analysis; the detection and analysis component is used to perform biochemical analysis on the target specimen; the mechanical transmission system is used to drive and control the operation of the detection and analysis component; the control module is used to manage and control the constant temperature control device, the optical path module, and the mechanical transmission system based on the data acquisition of the constant temperature control device and the optical path module.

[0047] The working principle of the above technical solution is as follows: The constant temperature control device proposed by the present invention can ensure that the temperature inside the analyzer remains stable, providing a suitable environment for biochemical analysis; the light source emitted by the optical path module is precisely adjusted to illuminate the target specimen, making the detection and analysis more accurate; the detection and analysis component contains highly sensitive sensors that can capture the biochemical reaction information of the specimen and convert it into analyzable data; the mechanical transmission system ensures that the detection and analysis component can move and operate according to a predetermined program through a precise mechanical structure; the control module, as the core of the entire system, receives data from the constant temperature control device and the optical path module, and after rapid processing, issues instructions to precisely regulate the constant temperature control device, the optical path module, and the mechanical transmission system to ensure the accuracy and reliability of biochemical analysis.

[0048] The beneficial effects of the above technical solution are as follows: By adopting the solution provided in this embodiment, the design of the fully automatic dry biochemical analyzer not only improves the efficiency of biochemical analysis but also reduces the errors caused by manual operation, providing strong support for medical research and clinical diagnosis.

[0049] In one embodiment, the frame device includes a base and an integrated bracket, and several silicone shock pads are arranged at the four corners of the base.

[0050] The working principle of the above technical solution is as follows: The design of the silicone shock pads in the present invention is to reduce the influence of external vibration on the precision components inside the analyzer and ensure the stability and accuracy during the biochemical analysis process; the integrated bracket is made of high-strength lightweight materials, which not only ensures the structural stability but also facilitates the overall handling and installation; on the frame device, by designing sliding rails and fixed buckles, various functional modules such as the constant temperature control device, the optical path module, and the detection and analysis component can be conveniently and quickly installed and disassembled, facilitating daily maintenance and upgrading.

[0051] The beneficial effects of the above technical solution are as follows: By adopting the solution provided in this embodiment, through the design of the frame device, not only the flexibility of the equipment is improved but also the service life of the instrument is extended.

[0052] In one embodiment, such asFigure 2 As shown in Figure 2 , the constant temperature control device includes a temperature control unit, a heating element, and a temperature sensor; the temperature control unit includes a temperature control circuit and a circulation fan; the temperature control circuit is used to heat the heating element to increase the internal air temperature of the fully automatic dry biochemical analyzer; the circulation fan is used to make the internal air of the fully automatic dry biochemical analyzer flow; the temperature sensor is used to collect the internal air temperature of the fully automatic dry biochemical analyzer in real time and feedback the collected air temperature to the temperature control unit.

[0053] The working principle of the above technical solution is: the temperature control unit accurately adjusts the heating power of the heating element through the temperature control circuit according to the temperature information fed back by the temperature sensor to keep the internal temperature of the analyzer constant; the continuous operation of the circulation fan effectively promotes the uniform distribution of the internal air of the analyzer, avoiding the situation of too high or too low local temperature, thus ensuring the consistency and stability of the temperature during the biochemical analysis process.

[0054] The beneficial effect of the above technical solution is: adopting the solution provided in this embodiment not only improves the accuracy of biochemical analysis, but also effectively reduces the influence of temperature changes on the analysis results, further enhancing the performance of the fully automatic dry biochemical analyzer.

[0055] In one embodiment, the temperature control unit integrates an environmental temperature compensation algorithm and dynamically adjusts the parameters of the PID controller according to the internal air temperature of the fully automatic dry biochemical analyzer fed back by the temperature sensor.

[0056] The working principle of the above technical solution is: the environmental temperature compensation algorithm built in the temperature control unit can intelligently identify and analyze the influence of the current environmental temperature on the internal temperature of the analyzer. When the temperature sensor feeds back the internal air temperature of the analyzer to the temperature control unit in real time, the algorithm will quickly calculate the adjustment amount of the PID controller parameters required to maintain the internal temperature constant. By dynamically adjusting the proportional, integral, and differential coefficients of the PID controller, the temperature control unit can accurately control the heating power of the heating element to compensate for the interference caused by environmental temperature changes and ensure that the internal temperature of the analyzer always remains within an ideal constant range.

[0057] The beneficial effect of the above technical solution is: adopting the solution provided in this embodiment effectively improves the flexibility and accuracy of temperature control, further enhancing the adaptability and analysis accuracy of the fully automatic dry biochemical analyzer under different environmental conditions.

[0058] In one embodiment, the optical path module includes a light source assembly and a photodetector; the light source assembly includes a light emitting device and a light receiving device; the light source assembly is an LED array, and the LED array adopts 12 or 16 independent LED light sources; each independent LED light source corresponds to an independent photoelectric detection channel; the photodetector is used to perform photoelectric signal conversion on the LED light source.

[0059] The working principle of the above technical solution is as follows: The LED array in the present invention serves as a light source component, capable of providing stable and high-intensity illumination, ensuring the stability and reliability of the optical signals during the biochemical analysis process. Each independent LED light source corresponds to an independent photoelectric detection channel. This design enables the analyzer to flexibly select specific LED light sources and corresponding photoelectric detection channels for different detection items or different reaction systems. When the LED light source emits light and irradiates the biochemical reaction sample, specific optical signal changes will occur in the sample during the biochemical reaction. These optical signals are then captured by the corresponding photoelectric detector and converted into electrical signals. The photoelectric detector features high sensitivity and fast response, capable of accurately converting the captured optical signals into electrical signals, which are then analyzed and processed by the subsequent signal processing unit to finally obtain accurate biochemical analysis results.

[0060] The beneficial effects of the above technical solution are as follows: By adopting the solution provided in this embodiment and through the design of the optical path module, the fully automatic dry biochemical analyzer can achieve accurate detection of multiple biochemical indicators.

[0061] In one embodiment, the optical path module further includes an intelligent attenuation compensation unit; the intelligent attenuation compensation unit includes:

[0062] Based on a current sensor and a light intensity detector, respectively collect the drive current and output light intensity of each LED light source;

[0063] According to the drive current and output light intensity, based on the Arrhenius correction model, predict the lifespan of each LED light source to obtain the lifespan prediction result of the LED light source;

[0064] According to the lifespan prediction result of the LED light source, set a multi-level alarm strategy;

[0065] If the lifespan prediction value in the lifespan prediction result of the LED light source is less than the set lifespan threshold, dynamically adjust the drive current according to the real-time light attenuation rate and correct the generated temperature drift term.

[0066] The working principle of the above technical solution is as follows: The core function of the intelligent attenuation compensation unit is to monitor and compensate for the attenuation of the LED light source in real time. During the operation of the analyzer, the current sensor will accurately measure the driving current of each LED light source, and the light intensity detector is responsible for detecting the corresponding output light intensity. These two parameters are the key indicators for evaluating the status of the LED light source. After obtaining the data of the driving current and output light intensity, the system will use the Arrhenius correction model to process these data. This model can comprehensively consider factors such as the working conditions and material characteristics of the LED light source, so as to more accurately predict the remaining life of the LED light source. The prediction result will be used as the basis for subsequent operations. Based on the life prediction result, the intelligent attenuation compensation unit will set a multi-level alarm strategy. When it is predicted that the life of a certain LED light source is about to reach or has fallen below the set life threshold, the system will trigger the corresponding alarm mechanism to remind the operator to pay attention and take measures in time. And this unit can also dynamically adjust the driving current of the LED light source according to the real-time light attenuation rate. Through this adjustment, it can effectively compensate for the light intensity attenuation of the LED light source caused by long-term operation, ensuring the stability and accuracy of the analyzer. At the same time, the system will also correct the drift term caused by temperature changes to further improve the reliability of the detection result.

[0067] The beneficial effects of the above technical solution are as follows: By adopting the solution provided in this embodiment, the service life of the LED light source can be significantly extended, and the detection error caused by the attenuation of the light source can be reduced, thereby improving the overall performance and reliability of the fully automatic dry biochemical analyzer.

[0068] In one embodiment, the mechanical transmission system includes a motor and a transmission component; the motor is used to provide power for the transmission component, and the transmission component is used to drive the operation of the detection and analysis component.

[0069] The working principle of the above technical solution is as follows: After the motor is started, through precise speed control, the power is transmitted to the transmission component; the transmission component then drives the detection and analysis component to perform various actions in an orderly manner according to the preset program and path, such as sample aspiration, distribution, mixing, and movement of the detection area, etc.; these actions work together to ensure that the sample can pass through the detection area accurately and efficiently, and at the same time, the detection and analysis component can accurately perform the detection task.

[0070] The beneficial effects of the above technical solution are as follows: By adopting the solution provided in this embodiment, the design of the entire mechanical transmission system fully considers stability and durability, ensuring that it can still maintain high precision and high efficiency under long-term continuous operation.

[0071] In one embodiment, the control module includes a main control chip and a data acquisition component; the data acquisition component is used to collect the temperature data of the constant temperature control device, the light source intensity data of the optical path module, and the position positioning data of the transmission component; the main control chip controls the operation of the constant temperature control device, the optical path module, and the mechanical transmission system based on the analysis and processing results of the temperature data, the light source intensity data, and the position positioning data, and based on the dynamic compensation strategy.

[0072] The dynamic compensation strategy includes temperature drift compensation, optical path attenuation compensation, and mechanical error compensation; the temperature drift compensation is: when the temperature difference is greater than the set temperature threshold, adjust the rotation speed of the circulation fan; the optical path attenuation compensation is: according to the set matching relationship curve between the LED current and the light intensity in the photodetector, correct the detection signal of the photodetector in real time; the mechanical error compensation is: update the control parameters of the mechanical transmission system based on the position positioning data.

[0073] The working principle of the above technical solution is as follows: The data acquisition component in the present invention monitors the temperature of the constant temperature control device, the light source intensity of the optical path module, and the precise position of the transmission component in real time; after receiving these data, the main control chip will immediately perform complex analysis and processing; according to the processing results, the main control chip will use the dynamic compensation strategy to finely regulate each component. When the temperature drifts, that is, the difference between the actual temperature and the ideal temperature exceeds the preset threshold, the main control chip will instruct the circulation fan to adjust the rotation speed to quickly restore the constant temperature state; when the light source intensity in the optical path module decays over time, the main control chip will correct the signal of the photodetector in real time according to the preset matching relationship curve between the LED current and the light intensity to ensure the accuracy of detection; for the small errors in the mechanical transmission system, the main control chip dynamically adjusts the control parameters based on the position positioning signal to maintain the high precision of the mechanical transmission; these series of actions are seamlessly connected to jointly ensure that the fully automatic dry biochemical analyzer can always complete tasks stably and accurately in a complex and changeable detection environment.

[0074] The beneficial effects of the above technical solution are as follows: Adopting the solution provided in this embodiment can significantly improve the detection accuracy and stability of the fully automatic dry biochemical analyzer; through real-time monitoring and dynamic compensation strategy, effectively cope with problems such as temperature drift, light source intensity attenuation, and mechanical transmission errors, ensuring the accuracy of detection results; the fast response and fine regulation ability of the main control chip enable the instrument to maintain stable performance when facing a complex and changeable detection environment; it also improves the automation level of the instrument, reduces the need for manual intervention, and thus improves the detection efficiency and reliability.

[0075] In one embodiment, the control module further includes a device health assessment unit, and the health assessment unit is used for:

[0076] Detect and obtain the equipment health assessment parameters of the fully automatic dry biochemical analyzer; the equipment health assessment parameters include the motor current ripple coefficient, the heating element resistance change rate, and the photodetector dark current value;

[0077] Detect and obtain the working environment parameters of the fully automatic dry biochemical analyzer; the working environment parameters include the ambient temperature and the ambient humidity;

[0078] Detect and obtain the working operation status data of the fully automatic dry biochemical analyzer; the working operation status data include the cumulative operation duration and the average daily detection times;

[0079] Establish a component life degradation model based on the long short-term memory network;

[0080] Based on the equipment health assessment detection parameters, the working environment parameters, and the working operation status data, use the component life degradation model to predict the life of the fully automatic dry biochemical analyzer. If the predicted remaining life is less than the set first life threshold, trigger the execution of the self-repair strategy; if the predicted remaining life is less than the set second life threshold, issue a warning reminder; the self-repair strategy includes optical path attenuation compensation and mechanical transmission system backlash compensation; optical path attenuation compensation includes performing reference optical path calibration; mechanical transmission system backlash compensation includes compensation based on the mapping table of the set position and the compensation amount.

[0081] The working principle of the above technical solution is as follows: The control module, through the integrated equipment health assessment unit, monitors and analyzes the key indicators of the fully automatic dry biochemical analyzer in real time; the motor current ripple coefficient reflects the stability of the motor operation state, the heating element resistance change rate reveals the aging degree of the heating system, and the photodetector dark current value is directly related to the sensitivity of the optical system; the accurate acquisition of these equipment health assessment parameters provides a solid foundation for subsequent life prediction; at the same time, the monitoring of the ambient temperature and humidity ensures that the analyzer can operate under the best working conditions, avoiding performance degradation or failures caused by environmental factors. The collection of working operation status data, such as the cumulative operation duration and the average daily detection times, provides an important basis for evaluating the usage intensity and maintenance requirements of the analyzer; the component life degradation model established based on the long short-term memory network can comprehensively consider historical data and the current state to achieve accurate prediction of the life of each component of the analyzer. When the predicted remaining life is lower than the preset first life threshold, the control module will automatically trigger the self-repair strategy, and through means such as optical path attenuation compensation and mechanical transmission system backlash compensation, effectively extend the service life of the analyzer, reduce downtime, and improve the overall operation efficiency; if the predicted remaining life further drops below the second life threshold, the system will issue a warning reminder to notify the operator to take further maintenance measures or replace key components in a timely manner to avoid potential failures and ensure the continuous and stable operation of the fully automatic dry biochemical analyzer.

[0082] The beneficial effects of the above technical solution are as follows: By adopting the solution provided in this embodiment, it is possible to achieve comprehensive health monitoring and life prediction of the fully automatic dry biochemical analyzer, significantly improving the maintenance efficiency and service life of the equipment; by real-time monitoring of key indicators such as the motor current ripple coefficient, the change rate of the heating element resistance, and the dark current value of the photodetector, potential operation problems of the equipment can be detected in a timely manner, providing accurate fault information for maintenance personnel and reducing the downtime caused by fault troubleshooting; the component life degradation model established based on the long short-term memory network can accurately predict the remaining life of each component of the analyzer, providing a scientific basis for formulating the equipment maintenance plan.

[0083] A production process of a fully automatic dry biochemical analyzer, as Figure 3 shown, includes the following steps:

[0084] S1: Install the silica gel shock pad on the base, and then assemble the integrated bracket;

[0085] S2: Implement modular assembly, specifically including:

[0086] S201: Assemble the constant temperature module, install the heating element and the temperature sensor into the biochemical analysis and detection area set inside the integrated bracket, and connect them to the set temperature control unit;

[0087] S202: Assemble the optical path module, install the light source component and the photodetector in the biochemical analysis and detection area set inside the integrated bracket, and perform optical path calibration using standard samples; the optical path calibration includes light source intensity calibration, wavelength accuracy calibration, and photodetector response linearity calibration;

[0088] S203: Install the detection and analysis component in the biochemical analysis and detection area configured inside the integrated bracket; among them, the guide rail of the target sample tray bracket in the detection and analysis component is integrally printed and produced based on the selective laser melting technology;

[0089] S204: Install the mechanical transmission system inside the integrated bracket, and perform motion accuracy testing and position positioning calibration;

[0090] S205: Install the control module inside the integrated bracket, and burn the control program;

[0091] S3: Conduct functional testing and performance verification on the fully automatic dry biochemical analyzer.

[0092] The working principle of the above technical solution is as follows: To achieve the production process of a fully automatic dry biochemical analyzer, the present invention first effectively reduces the vibration during the operation of the instrument through a silica gel shock pad to improve the detection accuracy; then modular assembly is implemented. Specifically, the temperature of the biochemical analysis detection area is precisely controlled by a heating element and a temperature sensor to ensure the consistency of the reaction conditions; then the optical path module is assembled. After strict calibration, the light source intensity is ensured to be stable, the wavelength is accurate, and the photodetector has good response linearity, thereby improving the accuracy and sensitivity of detection; the guide rail of the target sample tray support in the detection and analysis component is integrally printed and produced by selective laser melting technology, with high precision and stability, ensuring the accurate placement and movement of the sample; the mechanical transmission system undergoes motion precision testing and position positioning calibration to ensure the precise cooperation and movement of each component, improving the stability and reliability of the instrument; the control module is burned with a control program to achieve the automatic control and data processing of the instrument; finally, through functional testing and performance verification, it is ensured that the fully automatic dry biochemical analyzer can meet the design requirements and provide accurate, rapid, and reliable detection results for biochemical analysis.

[0093] The beneficial effects of the above technical solution are as follows: By adopting the solution provided in this embodiment, the design of the fully automatic dry biochemical analyzer not only improves the efficiency of biochemical analysis but also reduces the errors caused by manual operation, providing strong support for medical research and clinical diagnosis.

[0094] Obviously, those skilled in the art can make various changes and modifications to the present invention without departing from the spirit and scope of the present invention. Thus, if these modifications and variations of the present invention fall within the scope of the claims of the present invention and their equivalent technologies, the present invention is also intended to include these changes and modifications.

Claims

1. An automatic dry biochemical analyzer, characterized in that, It includes a frame device, a constant temperature control device, an optical path module, a detection and analysis component, a mechanical transmission system, and a control module; the constant temperature control device is used to implement constant temperature control, and the optical path module is used to provide the light source required for detection and analysis; the detection and analysis component is used to perform biochemical analysis on the target specimen; the mechanical transmission system is used to drive and control the operation of the detection and analysis component; the control module is used to manage and control the constant temperature control device, the optical path module, and the mechanical transmission system based on the data acquisition of the constant temperature control device and the optical path module.

2. The fully automatic dry biochemical analyzer according to claim 1, wherein The frame device includes a base and an integrated bracket, and several silicone shock pads are configured at the four corners of the base.

3. A fully automatic dry biochemical analyzer according to claim 1, wherein The constant temperature control device includes a temperature control unit, a heating element, and a temperature sensor; the temperature control unit includes a temperature control circuit and a circulation fan; the temperature control circuit is used to heat the heating element to increase the internal air temperature of the fully automatic dry biochemical analyzer; the circulation fan is used to make the internal air of the fully automatic dry biochemical analyzer flow; the temperature sensor is used to collect the internal air temperature of the fully automatic dry biochemical analyzer in real time and feedback the collected air temperature to the temperature control unit.

4. The fully automatic dry biochemical analyzer according to claim 3, wherein The temperature control unit integrates an environmental temperature compensation algorithm and dynamically adjusts the parameters of the PID controller according to the internal air temperature of the fully automatic dry biochemical analyzer feedback by the temperature sensor.

5. A fully automatic dry biochemical analyzer according to claim 1, characterized in that, The optical path module includes a light source component and a photodetector; the light source component includes a light emitting device and a light receiving device; the light source component is an LED array, and the LED array uses 12 or 16 independent LED light sources; each independent LED light source corresponds to an independent photoelectric detection channel; the photodetector is used to perform photoelectric signal conversion on the LED light source.

6. The fully automatic dry biochemical analyzer according to claim 5, wherein The optical path module also includes an intelligent attenuation compensation unit; the intelligent attenuation compensation unit includes: Based on a current sensor and a light intensity detector, respectively collect the drive current and output light intensity of each LED light source; According to the drive current and output light intensity, based on the Arrhenius correction model, predict the life of each LED light source to obtain the life prediction result of the LED light source; According to the life prediction result of the LED light source, set a multi-level alarm strategy; If the life prediction value in the life prediction result of the LED light source is less than the set life threshold, dynamically adjust the drive current according to the real-time light decay rate and correct the generated temperature drift term.

7. The fully automatic dry biochemical analyzer according to claim 1, characterized in that The mechanical transmission system includes a motor and a transmission component; the motor is used to provide power for the transmission component, and the transmission component is used to drive and control the operation of the detection and analysis component.

8. A fully automatic dry biochemical analyzer according to claim 7, characterized in that, The control module includes a main control chip and a data acquisition component; the data acquisition component is used to collect the temperature data of the constant temperature control device, the light source intensity data of the optical path module, and the position positioning data of the transmission component; the main control chip controls the operation of the constant temperature control device, the optical path module, and the mechanical transmission system based on the analysis and processing results of the temperature data, the light source intensity data, and the position positioning data, based on the dynamic compensation strategy; The dynamic compensation strategy includes temperature drift compensation, optical path attenuation compensation, and mechanical error compensation. Temperature drift compensation: When the temperature difference is greater than the set temperature threshold, adjust the rotational speed of the circulation fan. Optical path attenuation compensation: According to the set matching relationship curve between the LED current and the light intensity in the photodetector, real-time correct the detection signal of the photodetector. Mechanical error compensation: Based on the position positioning data, update the control parameters of the mechanical transmission system.

9. A fully automatic dry biochemical analyzer according to claim 1, characterized in that, The control module further includes a device health assessment unit, and the health assessment unit is used for: Detect and obtain the device health assessment parameters of the fully automatic dry biochemical analyzer. The device health assessment parameters include the motor current ripple coefficient, the heating element resistance change rate, and the photodetector dark current value. Detect and obtain the working environment parameters of the fully automatic dry biochemical analyzer. The working environment parameters include the ambient temperature and the ambient humidity. Detect and obtain the working operation status data of the fully automatic dry biochemical analyzer. The working operation status data includes the cumulative operation duration and the average daily detection times. Establish a component life degradation model based on the long short-term memory network. Based on the device health assessment detection parameters, the working environment parameters, and the working operation status data, use the component life degradation model to predict the life of the fully automatic dry biochemical analyzer. If the predicted remaining life is less than the set first life threshold, trigger the execution of the self-repair strategy. If the predicted remaining life is less than the set second life threshold, issue a warning reminder. The self-repair strategy includes optical path attenuation compensation and mechanical transmission system backlash compensation. Optical path attenuation compensation includes performing reference optical path calibration. Mechanical transmission system backlash compensation includes compensation based on the set mapping table of position and compensation amount.

10. A production process of a fully automatic dry biochemical analyzer, characterized in that, It includes the following steps: S1: Install the silica gel shock pad on the base, and then assemble the integrated bracket. S2: Implement modular assembly, specifically including: S201: Assemble the constant temperature module, install the heating element and the temperature sensor into the biochemical analysis detection area set inside the integrated bracket, and connect them to the set temperature control unit. S202: Assemble the optical path module, install the light source component and the photodetector in the biochemical analysis detection area set inside the integrated bracket, and perform optical path calibration using a standard sample. Optical path calibration includes light source intensity calibration, wavelength accuracy calibration, and photodetector response linearity calibration. S203: Install the detection and analysis component in the biochemical analysis detection area configured inside the integrated bracket. Among them, the guide rail of the target sample tray bracket in the detection and analysis component is integrally printed and produced based on the selective laser melting technology. S204: Install the mechanical transmission system inside the integrated bracket, and perform motion accuracy testing and position positioning calibration. S205: Install the control module inside the integrated bracket, and burn the control program. S3: Conduct functional testing and performance verification on the fully automatic dry biochemical analyzer.

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