Hard plastic needle and preparation method thereof
The hard plastic needle with a composite polyetherketone and treated nano-silica structure addresses the issues of imprecision and complexity in traditional scar excision by enabling precise drug delivery and reducing tissue damage, enhancing surgical efficiency and patient comfort.
Patent Information
- Application Number
- CN202510409462.7
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-04-02
- Publication Date
- 2025-07-15
AI Technical Summary
Traditional scar removal needles are cumbersome, inaccurate administration, increase patient pain, and metal materials are prone to damage surrounding tissue.
A hard plastic needle is prepared using polyether ether ketone material, and holes are punched at the needle connection, combined with nano-silica treatment to improve the rigidity and toughness of the material, so as to achieve drug delivery while peeling.
Reduce surgical operation complexity, improve medication accuracy, reduce patient pain, low cost and no damage to surrounding tissue.
Smart Images
Figure CN120304919A_ABST
Abstract
Description
Technical Field
[0001] The present invention relates to the technical field of hard plastic needles, and particularly to a hard plastic needle and a preparation method thereof. Background Art
[0002] Scar stripping surgery refers to a surgery that promotes the formation of fibrous connective tissue by separating subcutaneous adhesions to reduce the area of the scar.
[0003] In traditional scar stripping surgery, a stripping needle is first used to strip the scar adhesion tissue, and then the instrument is replaced to inject the medicine at the stripping site. This not only has cumbersome operation steps, but also when injecting the medicine, the stripping needle has already been separated from the skin tissue. Therefore, it is difficult to accurately find the site stripped by the stripping needle before injecting the medicine, resulting in inaccurate drug administration and poor repair effect of the scar adhesion tissue. In addition, the scar tissue needs to be pricked at least twice, which not only damages the body tissue, but also increases the patient's pain and the complexity of the surgical operation. Moreover, the traditional scar stripping needle is made of metal material, which not only has a high cost, but also because the stripping needle made of metal material has a very high hardness, it is easy to damage the surrounding normal tissue during the actual stripping process.
[0004] Therefore, there is a need to find a scar stripping needle that can accurately administer drugs, reduce the complexity of scar stripping surgery operation and relieve the patient's pain, so as to solve the problems of cumbersome operation, inaccurate drug administration and increased patient pain during the stripping surgery with the traditional scar stripping needle. Summary of the Invention
[0005] In view of this, the purpose of the present invention is to provide a hard plastic needle and a preparation method thereof, so as to solve the problems of cumbersome operation, inaccurate drug administration and increased patient pain during the stripping surgery with the traditional scar stripping needle.
[0006] The present invention solves the above technical problems through the following technical means:
[0007] A hard plastic needle, the hard plastic needle includes a syringe barrel and a push rod. The syringe barrel includes an injection barrel, a medicine outlet part and a needle head. One end of the medicine outlet part is connected with the needle head, a through hole with a diameter of 100 - 300 nm is opened on the medicine outlet part, the other end of the medicine outlet part is connected with the injection barrel, drugs are loaded in the injection barrel, and a piston is arranged on the push rod and is slidably connected with the injection barrel.
[0008] After loading the drugs into the injection barrel, the needle head and the medicine outlet part are inserted into the affected area, the push rod is pushed, and the piston pushes the drugs to flow out from the through hole on the medicine outlet part. At this time, the drugs reach the affected area through the through hole of the medicine outlet part.
[0009] The present invention also discloses a preparation method of the hard plastic needle, and the specific preparation method is as follows:
[0010] (1) Prepare the polyetheretherketone composite material for the hard plastic needle. Put the polyetheretherketone composite material into an oven and dry it at 150 - 160 °C for 2 - 3 h to obtain the dried polyetheretherketone composite material;
[0011] (2) Take the dried polyetheretherketone composite material, put it into an injection molding machine, and carry out injection molding at a barrel temperature of 380 - 400 °C, a mold temperature of 180 - 220 °C, and an injection pressure of 120 - 140 Mpa for 20 - 30 s under heat preservation and pressure holding conditions to obtain a syringe barrel; then take the dried polyetheretherketone composite material and put it into an injection molding machine to carry out injection molding according to the same conditions to obtain a push rod;
[0012] (3) Carry out laser drilling on the medicine outlet part of the syringe barrel to punch through holes, and then install the syringe barrel and the push rod so that the syringe barrel and the push rod are slidably connected to obtain a hard plastic needle.
[0013] The present invention uses a polyetheretherketone material to prepare a hard plastic needle, and punches holes in the medicine outlet part at the connection with the needle head. When peeling scar tissue, drugs can be synchronously administered through the through - hole structure. The drugs are accurately distributed to the wound during the peeling process, directly acting on the peeled skin tissue, reducing the complexity of surgical operations and the pain of patients at the same time.
[0014] The present invention uses a polyetheretherketone material to prepare a hard plastic needle. On the one hand, the plastic texture material has strong plasticity, can be processed into complex shapes through precision forming technology, is easy to punch holes, and obtains a through - hole structure with appropriate pore diameter and uniform distribution, realizing the drug release stability during the peeling process. Moreover, polyetheretherketone has excellent biocompatibility compared with traditional metal materials such as stainless steel.
[0015] Furthermore, the polyetheretherketone composite material includes the following raw materials:
[0016] Polyetheretherketone, nano - silica, hydrochloric acid, o - carboxybenzaldehyde, p - toluenesulfonic acid, n - butylamine, sucrose stearate, sodium hyaluronate.
[0017] Furthermore, the preparation method of the polyetheretherketone composite material is as follows:
[0018] A: Immerse nano - silica in a 0.5 wt% hydrochloric acid solution, stir and disperse it, then soak it overnight, filter to remove the filtrate, add it to water and stir and disperse, add o - carboxybenzaldehyde and p - toluenesulfonic acid, heat up to 80 - 90 °C and stir and react for 4 - 6 h. After the reaction is completed, remove the filtrate, wash it with clear water, and then dry it to obtain the primary - treated nano - silica;
[0019] B: Add the primary - treated nano - silica to water, stir and disperse it, then add n - butylamine, heat up to 40 - 60 °C and stir and react for 2 - 4 h. After the reaction is completed, naturally cool it to room temperature, then add sucrose stearate, mix it evenly, and let it stand overnight. Remove the filtrate and then dry it to obtain the nano - silica reinforcing agent;
[0020] C: Add nano-silica reinforcing agent to ethanol, stir and disperse it, then add polyether ether ketone and sodium hyaluronate, stir and mix at a speed of 800 - 1000 r / min for 10 - 20 min, then filter to remove the filtrate, and vacuum dry at 165 °C for 3 h. After drying, put it into an extruder and carry out melt extrusion at a barrel temperature of 380 °C and a screw speed of 60 r / min to obtain a polyether ether ketone composite material.
[0021] The hard plastic needle made of polyether ether ketone has lower mechanical strength and insufficient rigidity compared with traditional metal materials. Therefore, when peeling deep adhesions, large-area or tough scar tissues, it is easy to bend and break, which limits its application. Therefore, the present invention prepares a composite material by adding nano-silica to improve the mechanical properties of polyether ether ketone, so as to improve the rigidity of the hard plastic needle and thus improve its applicability in complex scar peeling surgeries. However, nano-silica has a small particle size, a large specific surface area, and is easy to agglomerate. Directly adding it to polyether ether ketone will affect the overall mechanical properties of the composite material due to uneven dispersion. Therefore, it is necessary to treat nano-silica to improve its dispersion in polyether ether ketone and better play its performance enhancement role.
[0022] Specifically, the present invention first conducts a heating reaction between o-carboxybenzaldehyde and nano-silica. The o-carboxybenzaldehyde combines with the hydroxyl groups on the nano-silica through esterification. On the one hand, it reduces the surface polarity of nano-silica, thereby improving the dispersion of nano-silica in low-polarity polyether ether ketone. On the other hand, after the rigid benzene ring structure in o-carboxybenzaldehyde binds to the surface of nano-silica, it can further increase the rigidity of the polyether ether ketone composite material. However, the introduction of rigid groups also easily reduces the toughness of the composite material, and the hard plastic needle prepared is also prone to cracking during application. Therefore, the present invention further uses n-butylamine for treatment. The n-butylamine further reacts and combines with the nano-silica treated with o-carboxybenzaldehyde, thereby introducing flexible alkyl chains on the surface of nano-silica and adding it to polyether ether ketone to prepare a composite material. The flexible alkyl chains can better disperse stress when subjected to external forces and improve the toughness of the composite material. Further, the present invention then selects the surfactant sucrose stearate with a rigid cyclic structure and flexible segments to further treat the nano-silica, further improving the dispersion of nano-silica in polyether ether ketone, and at the same time further increasing the number of rigid groups and flexible segments on the surface of nano-silica added to polyether ether ketone, thereby further improving the mechanical properties of the polyether ether ketone composite material.
[0023] Further, the particle size of the nano-silica is 10 - 50 nm.
[0024] Further, in the step A, the mass ratio of nano-silica, o-carboxybenzaldehyde, and p-toluenesulfonic acid is (3-5):(0.2-0.4):(0.01-0.02).
[0025] Further, in the step B, the mass ratio of the primary-treated nano-silica, n-butylamine, and sucrose stearate is (3-5):(0.1-0.2):(0.1-0.2).
[0026] Further, in the step C, the mass ratio of the nano-silica reinforcing agent, polyetheretherketone, and hyaluronic acid is (3-5):(200-300):(0.1-0.2).
[0027] The present invention also discloses the application of the hard plastic needle in scar stripping surgery.
[0028] Beneficial effects:
[0029] 1. The present invention uses polyetheretherketone as the main raw material to prepare a needle for scar stripping surgery, and punches holes in the drug delivery part at the connection of the needle tip, so as to better achieve drug delivery while stripping in scar stripping surgery. It can not only reduce surgical operations and relieve the pain of patients, but also the hard plastic needle prepared with this material has the characteristics of low cost and light weight, and has good application prospects.
[0030] 2. The present invention prepares a nano-silica reinforcing agent by treating nano-silica, adds it to polyetheretherketone to prepare a polyetheretherketone composite material, and then injects it to obtain a hard plastic needle, which improves the mechanical properties of the polyetheretherketone composite material, obtains a hard plastic needle with good rigidity and better toughness, enhances its applicability in complex scar stripping surgery, and can prevent the influence on the good performance of the polyetheretherketone material itself when directly modifying the polyetheretherketone by treating the nano-silica and adding it to the polyetheretherketone. Description of the drawings
[0031] Figure 1 : It is a structural picture of the hard plastic needle of the present invention.
[0032] Reference numerals:
[0033] 1 - syringe barrel; 2 - push rod; 3 - injection cylinder; 4 - drug delivery part; 5 - needle tip; 6 - through hole. Specific embodiments
[0034] The following will describe the present invention in detail with reference to specific embodiments and drawings:
[0035] Such as Figure 1As shown in the figure, the present invention discloses a structure of a hard plastic needle. Specifically, the hard plastic needle includes a syringe barrel 1 and a push rod 2. The syringe barrel includes an injection barrel 3, a medicine outlet part 4, and a needle head 5. One end of the medicine outlet part 4 is connected to the needle head 5, and a plurality of through holes 6 with a size of 100 - 300 nm are provided on the medicine outlet part 4. The other end of the medicine outlet part 4 is connected to the injection barrel 3. The medicine is loaded in the injection barrel 3, and a piston is arranged on the push rod 2 and is slidably connected to the injection barrel 3.
[0036] After loading the medicine into the injection barrel of the hard plastic needle of the present invention, the needle head and the medicine outlet part are inserted deep into the affected area. After peeling the affected area with the needle head, the push rod is pushed, and the piston is used to make the medicine flow out from the through holes on the medicine outlet part to the peeled affected area, achieving the effect of administering medicine while peeling the scar tissue, thereby reducing the complexity of the surgical operation. The outer wall structure of the medicine outlet part is a curved surface, and the length is 0.4 - 1 cm, preferably 0.6 cm. This length is beneficial to ensuring that a sufficient amount of medicine in the injection barrel enters and is stored in the medicine outlet part and flows out through the through hole structure in a timely manner. The through hole is 100 - 300 nm, preferably 150 nm. This through hole size is beneficial to the release and injection of common medicines in the field of cosmetic repair.
[0037] In addition, the present invention also discloses a preparation method of the above hard plastic needle. Before preparing the hard plastic needle, it is necessary to first prepare the polyetheretherketone composite material used, which is specifically as follows. The particle size of the nano - silica used below is 10 nm.
[0038] Example 1: Preparation of Polyetheretherketone Composite Material 1
[0039] A: Immerse 4 g of nano - silica in 20 g of 0.5 wt% hydrochloric acid solution, stir and disperse, then soak overnight. After that, filter to remove the filtrate, add it to 80 g of water, stir and disperse, add 0.3 g of o - carboxybenzaldehyde and 0.015 g of p - toluenesulfonic acid, raise the temperature to 85 °C, stir and react for 5 h. After the reaction is completed, remove the filtrate, wash with clear water, and then place it in an oven to dry at 65 °C to obtain the primary - treated nano - silica.
[0040] B: Add 4 g of the primary - treated nano - silica to 80 g of water, stir and disperse, then add 0.15 g of n - butylamine, raise the temperature to 50 °C, stir and react for 3 h. After the reaction is completed, naturally cool to room temperature, then add 0.15 g of sucrose stearate, mix evenly, and let it stand overnight. After removing the filtrate, place it in an oven to dry at 65 °C to obtain the nano - silica reinforcing agent.
[0041] C: Add 4 g of the nano - silica reinforcing agent to 400 g of ethanol, stir and disperse, then add 250 g of polyetheretherketone and 0.15 g of sodium hyaluronate, stir and mix at a speed of 900 r / min for 15 min. After that, filter to remove the filtrate, vacuum - dry at 165 °C for 3 h. After drying is completed, put it into an extruder and carry out melt extrusion at a barrel temperature of 380 °C and a screw speed of 60 r / min to obtain the polyetheretherketone composite material.
[0042] Example 2: Preparation of Polyetheretherketone Composite Material II
[0043] A: Immerse 3 g of nano-silica in 15 g of 0.5 wt% hydrochloric acid solution, stir and disperse, then soak overnight. After that, filter to remove the filtrate, add it to 60 g of water, stir and disperse, add 0.2 g of o-carboxybenzaldehyde and 0.01 g of p-toluenesulfonic acid, heat up to 80 °C and stir for 6 h. After the reaction is completed, remove the filtrate, wash with water, and then dry in an oven at 65 °C to obtain the primary treated nano-silica;
[0044] B: Add 3 g of the primary treated nano-silica to 60 g of water, stir and disperse, then add 0.1 g of n-butylamine, heat up to 40 °C and stir for 4 h. After the reaction is completed, cool naturally to room temperature, then add 0.1 g of sucrose stearate, mix evenly and let stand overnight. After removing the filtrate, dry in an oven at 65 °C to obtain the nano-silica enhancer;
[0045] C: Add 3 g of the nano-silica enhancer to 300 g of ethanol, stir and disperse, then add 200 g of polyetheretherketone and 0.1 g of sodium hyaluronate, stir and mix at 800 r / min for 20 min. After that, filter to remove the filtrate and dry in vacuum at 165 °C for 3 h. After drying, put it into an extruder and carry out melt extrusion at a barrel temperature of 380 °C and a screw speed of 60 r / min to obtain the polyetheretherketone composite material.
[0046] Example 3: Preparation of Polyetheretherketone Composite Material III
[0047] A: Immerse 5 g of nano-silica in 25 g of 0.5 wt% hydrochloric acid solution, stir and disperse, then soak overnight. After that, filter to remove the filtrate, add it to 100 g of water, stir and disperse, add 0.4 g of o-carboxybenzaldehyde and 0.02 g of p-toluenesulfonic acid, heat up to 90 °C and stir for 4 h. After the reaction is completed, remove the filtrate, wash with water, and then dry in an oven at 65 °C to obtain the primary treated nano-silica;
[0048] B: Add 5 g of the primary treated nano-silica to 100 g of water, stir and disperse, then add 0.2 g of n-butylamine, heat up to 60 °C and stir for 2 h. After the reaction is completed, cool naturally to room temperature, then add 0.2 g of sucrose stearate, mix evenly and let stand overnight. After removing the filtrate, dry in an oven at 65 °C to obtain the nano-silica enhancer;
[0049] C: Add 5 g of nano-silica reinforcing agent to 500 g of ethanol, stir and disperse, then add 300 g of polyether ether ketone and 0.2 g of sodium hyaluronate, stir and mix at a speed of 1000 r / min for 12 min, then filter to remove the filtrate, and dry in vacuum at 165 °C for 3 h. After drying, put it into an extruder and carry out melt extrusion at a barrel temperature of 380 °C and a screw speed of 60 r / min to obtain a polyether ether ketone composite material.
[0050] Comparative Example 1: Preparation of polyether ether ketone composite material
[0051] In contrast to Example 1, the difference is only that in Comparative Example 1, o-carboxybenzaldehyde is not added in step A during the preparation of the polyether ether ketone composite material to treat the nano-silica. The specific steps are as follows:
[0052] A: Immerse 4 g of nano-silica in 20 g of 0.5 wt% hydrochloric acid solution, stir and disperse, then soak overnight, then filter to remove the filtrate, wash with water, and place in an oven to dry at 65 °C to obtain primary-treated nano-silica;
[0053] B - C: The same as in Example 1.
[0054] Comparative Example 2: Preparation of polyether ether ketone composite material
[0055] In contrast to Example 1, the difference is only that in Comparative Example 2, n-butylamine is not used to treat the nano-silica in step B during the preparation of the polyether ether ketone composite material. The specific steps are as follows:
[0056] A: The same as in Example 1;
[0057] B: Add 4 g of primary-treated nano-silica to 80 g of water, stir and disperse, then add 0.15 g of sucrose stearate, mix evenly, and let stand overnight. After removing the filtrate, place it in an oven and dry at 65 °C to obtain a nano-silica reinforcing agent;
[0058] C: The same as in Example 1.
[0059] Comparative Example 3: Preparation of polyether ether ketone composite material
[0060] In contrast to Example 1, the difference is only that in Comparative Example 3, sucrose stearate is not added in step B during the preparation of the polyether ether ketone composite material. The specific steps are as follows:
[0061] A: The same as in Example 1;
[0062] B: Add 4 g of primary-treated nano-silica to 80 g of water, stir and disperse, then add 0.15 g of n-butylamine, heat up to 50 °C and stir for 3 h. After the reaction is completed, cool naturally to room temperature. After removing the filtrate, place it in an oven and dry at 65 °C to obtain a nano-silica reinforcing agent;
[0063] C: The same as in Example 1.
[0064] Comparative Example 4: Preparation of polyetheretherketone composite
[0065] In contrast to Example 1, the difference is only that in Comparative Example 4, the polyetheretherketone composite is prepared by mixing conventional nano-silica with polyetheretherketone. The specific process is as follows:
[0066] Add 4 g of nano-silica into 400 g of ethanol, stir and disperse it, then add 250 g of polyetheretherketone and 0.15 g of sodium hyaluronate. Stir and mix at a speed of 900 r / min for 15 min, then filter to remove the filtrate and dry it in vacuum at 165 °C for 3 h. After drying, put it into an extruder and carry out melt extrusion at a barrel temperature of 380 °C and a screw speed of 60 r / min to obtain the polyetheretherketone composite.
[0067] Comparative Example 5: Preparation of polyetheretherketone composite
[0068] In contrast to Example 1, the difference is only that in Comparative Example 7, no nano-silica reinforcing agent is added during the preparation of the polyetheretherketone composite. The specific process is as follows:
[0069] Add 250 g of polyetheretherketone and 0.15 g of sodium hyaluronate into 400 g of ethanol, stir and mix at a speed of 900 r / min for 15 min, then filter to remove the filtrate and dry it in vacuum at 165 °C for 3 h. After drying, put it into an extruder and carry out melt extrusion at a barrel temperature of 380 °C and a screw speed of 60 r / min to obtain the polyetheretherketone composite.
[0070] Comparative Example 6: Preparation of polyetheretherketone composite
[0071] In contrast to Example 1, the difference is only that in Comparative Example 6, the addition amount of the nano-silica reinforcing agent during the preparation of the polyetheretherketone composite is 2 g, and the remaining steps are the same as in Example 1.
[0072] Comparative Example 7: Preparation of polyetheretherketone composite
[0073] In contrast to Example 1, the difference is only that in Comparative Example 7, the addition amount of the nano-silica reinforcing agent during the preparation of the polyetheretherketone composite is 6 g, and the remaining steps are the same as in Example 1.
[0074] Example 4: Preparation of hard plastic needle
[0075] (1) Put the polyetheretherketone composite prepared according to the method of Example 1 into an oven and dry it at 155 °C for 2.5 h to obtain the dried polyetheretherketone composite;
[0076] (2) Take the dried polyetheretherketone composite material, put it into an injection molding machine, and keep it warm and pressurized for 30 s at a barrel temperature of 390 °C, a mold temperature of 195 °C, and an injection pressure of 130 Mpa to obtain a syringe by injection molding; then take the dried polyetheretherketone composite material and put it into the injection molding machine to obtain a push rod by injection molding under the same conditions;
[0077] (3) Laser drill through holes with a diameter of 150 nm on the medicine outlet part of the syringe, and then install the syringe, the push rod, and the piston so that the syringe and the push rod are slidably connected to obtain a hard plastic needle. The injection barrel length of the obtained hard plastic needle is 4 cm, the injection barrel diameter is 2 cm, the medicine outlet part length is 0.6 cm, and the needle head length is 0.6 cm.
[0078] Experiment: Mechanical property determination experiment of polyetheretherketone composite material
[0079] In complex scar dissection surgery, higher requirements are placed on the mechanical properties of the hard plastic needle. Therefore, in order to further verify the mechanical properties of the polyetheretherketone composite material prepared by the present invention, the elastic modulus (ISO 527-4) and flexural strength (ISO 178-2019) of the polyetheretherketone composite materials prepared in Example 1 and Comparative Examples 1-7 were respectively detected, and the data are shown in Table 1.
[0080] Table 1
[0081]
[0082] According to the data analysis in Table 1, it can be seen that:
[0083] The elastic modulus and flexural strength of the polyetheretherketone composite material of Example 1 prepared according to the method of the present invention can both reach relatively high values. The elastic modulus reaches 5.7 GPa, and the flexural strength reaches 152.8 MPa. The polyetheretherketone composite material prepared by the present invention has good mechanical properties, good rigidity and toughness, indicating that when using this material to prepare a hard plastic needle, it can smoothly penetrate into the scar tissue for dissection without breaking or cracking, and thus can achieve good dissection and repair of the scar tissue.
[0084] In Comparative Examples 1-7, in the case of lacking treatment steps or changing the addition amount of the nano-silica reinforcing agent, the overall performance of the polyetheretherketone composite material decreases to varying degrees, indicating that after treating nano-silica according to the method of the present invention to prepare a nano-silica reinforcing agent and then adding it to polyetheretherketone to prepare a polyetheretherketone composite material, the mechanical properties of the polyetheretherketone composite material can be effectively improved, and a hard plastic needle with good rigidity and toughness can be prepared, which is beneficial to improving its application in complex scar dissection surgery.
[0085] The above embodiments are only used to illustrate the technical solutions of the present invention and not to limit them. Although the present invention has been described in detail with reference to the preferred embodiments, those of ordinary skill in the art should understand that the technical solutions of the present invention can be modified or equivalently replaced without departing from the gist and scope of the technical solutions of the present invention, and they should all be covered within the scope of the claims of the present invention. The technologies, shapes, and structures not described in detail in the present invention are all well-known technologies.
Claims
1. A hard plastic needle, characterized in that, The hard plastic needle includes a syringe barrel and a push rod. The syringe barrel includes an injection barrel, a medicine outlet part, and a needle head. One end of the medicine outlet part is connected to the needle head. A through hole with a diameter of 100 - 300 nm is formed on the medicine outlet part. The other end of the medicine outlet part is connected to the injection barrel. Medicine is filled in the injection barrel. A piston is arranged on the push rod and is slidably connected to the injection barrel.
2. A preparation method of a hard plastic needle, characterized in that, The preparation method of the hard plastic needle is as follows: (1) Prepare the polyetheretherketone composite material used for the hard plastic needle. Put the polyetheretherketone composite material into an oven and dry it at 150 - 160 °C for 2 - 3 h to obtain the dried polyetheretherketone composite material; (2) Take the dried polyetheretherketone composite material, put it into an injection molding machine, and keep it warm and under pressure at a barrel temperature of 380 - 400 °C, a mold temperature of 180 - 220 °C, and an injection pressure of 120 - 140 Mpa for 20 - 30 s to injection mold the syringe barrel; then take the dried polyetheretherketone composite material and put it into the injection molding machine to injection mold the push rod under the same conditions; (3) Perform laser drilling on the medicine outlet part of the syringe barrel to form a through hole, and then install the syringe barrel and the push rod so that the syringe barrel and the push rod are slidably connected to obtain the hard plastic needle.
3. According to the preparation method of a hard plastic needle described in claim 2, the special feature is that the polyetheretherketone composite material includes the following raw materials: Polyetheretherketone, nano - silicon dioxide, hydrochloric acid, o - carboxybenzaldehyde, p - toluenesulfonic acid, n - butylamine, sucrose stearate, sodium hyaluronate.
4. The preparation method of a hard plastic needle according to claim 3, characterized in that, The preparation method of the polyetheretherketone composite material is as follows: A: Immerse the nano - silicon dioxide in a 0.5 wt% hydrochloric acid solution, stir and disperse it, then soak it overnight. Then filter to remove the filtrate, add it to water and stir and disperse. Add o - carboxybenzaldehyde and p - toluenesulfonic acid, heat up to 80 - 90 °C and stir and react for 4 - 6 h. After the reaction is completed, remove the filtrate, wash it with clear water, and then dry it to obtain the primary treated nano - silicon dioxide; B: Add the primary treated nano - silicon dioxide to water and stir and disperse it, then add n - butylamine, heat up to 40 - 60 °C and stir and react for 2 - 4 h. After the reaction is completed, naturally cool it to room temperature, then add sucrose stearate and mix evenly, and let it stand overnight. Remove the filtrate and then dry it to obtain the nano - silicon dioxide reinforcing agent; C: Add the nano - silicon dioxide reinforcing agent to ethanol and stir and disperse it, then add polyetheretherketone and sodium hyaluronate, stir and mix at a speed of 800 - 1000 r / min for 10 - 20 min. Then filter to remove the filtrate and vacuum dry it at 165 °C for 3 h. After drying is completed, put it into an extruder and perform melt extrusion at a barrel temperature of 380 °C and a screw speed of 60 r / min to obtain the polyetheretherketone composite material.
5. The preparation method of a hard plastic needle according to claim 4, characterized in that, The particle size of the nano - silicon dioxide is 10 - 50 nm.
6. The preparation method of a hard plastic needle according to claim 5, characterized in that, In step A, the mass ratio of nano - silicon dioxide, o - carboxybenzaldehyde, and p - toluenesulfonic acid is (3 - 5):(0.2 - 0.4):(0.01 - 0.02).
7. The preparation method of a hard plastic needle according to claim 6, wherein, In step B, the mass ratio of the primary treated nano - silicon dioxide, n - butylamine, and sucrose stearate is (3 - 5):(0.1 - 0.2):(0.1 - 0.2).
8. The preparation method of a hard plastic needle according to claim 7, characterized in that, In step C, the mass ratio of the nano-silica reinforcing agent, polyetheretherketone, and hyaluronic acid is (3-5):(200-300):(0.1-0.2).
9. Use of the hard plastic needle according to any one of claims 1 to 8 in a scar stripping operation.