Rheum officinale powder acupoint application and application method thereof

Abstract

The invention discloses a rhubarb powder acupoint application and a use method thereof, the rhubarb powder acupoint application comprises the following raw materials: rhubarb, raw bighead atractylodes rhizome, immature bitter orange and semen cannabis, and through specific formula combination and application operation, the effects of regulating spleen and stomach and promoting digestion are achieved. The application method comprises the steps of environment preparation, material preparation, device preparation, application indwelling and post-treatment. Through scientific formula combination and application operation, the traditional application limitation is broken through, and the rhubarb powder is expanded to the field of treating various symptoms such as qi deficiency and weakness, abdominal distension and dry stool. The innovation not only enriches the use scene of the rhubarb powder, but also provides a new thought for the effect of the rhubarb powder in traditional Chinese medicine treatment. And meanwhile, by adopting an acupoint application form, the patient can conveniently use the device in daily life, so that the light weight and convenience of disease management are realized.

Description

Technical Field

[0001] The present invention relates to the technical field of traditional Chinese medicine preparations for treatment, and particularly to a rhubarb powder acupoint application and its using method. Background Art

[0002] In the field of traditional Chinese medicine, the treatment of problems such as qi deficiency and weakness, abdominal distension, and dry stools has always been a key focus of long-term attention. As an important component in traditional Chinese medicine, rhubarb powder has been highly favored because of its functions of moistening the intestines and promoting defecation, and strengthening the spleen and stopping diarrhea. However, its application scope is mainly limited to the treatment of dry stools, and it fails to fully address the symptoms of qi deficiency and weakness and abdominal distension. In recent years, acupoint application, as a new traditional Chinese medicine treatment method, has gradually attracted attention due to its convenience and operability.

[0003] However, most of the existing rhubarb powder acupoint application agents have some problems, such as:

[0004] The formula of the rhubarb powder acupoint application agent is single, usually only targeting a certain symptom (such as dry stools), and unable to effectively regulate qi deficiency and weakness and abdominal distension simultaneously;

[0005] The existing acupoint application schemes usually have cumbersome steps, and the operation steps lack guidance, making it difficult for patients or users to complete the application operation independently, and prone to operation errors or local injuries;

[0006] Many existing acupoint application agents lack strict scientific verification in terms of formula ratio and using method, only staying on the basis of experience or tradition, and without sufficient clinical trial data to support their curative effects;

[0007] The existing acupoint application schemes usually adopt a unified formula and dosage, and fail to make personalized adjustments according to the specific constitution and health status of patients. Summary of the Invention

[0008] Aiming at the defects of the existing technology, the purpose of the present invention is to provide a rhubarb powder acupoint application and its using method to solve the problems raised in the above background art.

[0009] The present invention adopts the following technical solutions to solve the technical problems:

[0010] The present invention provides a rhubarb powder acupoint application, and the formula is composed of the following raw materials: rhubarb, raw atractylodes macrocephala, immature bitter orange, and semen cannabis. Through specific formula combination and application operation, the effects of regulating the spleen and stomach and promoting digestion are achieved, and it includes:

[0011] For the treatment of qi deficiency and weakness, 10% of rhubarb powder + 15% of raw atractylodes macrocephala powder;

[0012] For the treatment of abdominal distension, 10% of rhubarb + 10% of immature bitter orange powder;

[0013] For treating dry stools, 10% rhubarb powder + 15% semen cannabis powder.

[0014] Preferably, the formula is: rhubarb (10%), raw atractylodes macrocephala (5%), immature bitter orange (5%), semen cannabis (5%). Mix rhubarb, raw atractylodes macrocephala, immature bitter orange and semen cannabis to make rhubarb powder, and apply it on the Zhongwan acupoint for regulating the spleen and stomach function and treating qi deficiency and weakness.

[0015] Preferably, the formula is: rhubarb (10%), raw atractylodes macrocephala (5%), immature bitter orange (5%). Mix rhubarb, raw atractylodes macrocephala and immature bitter orange to make rhubarb powder, and apply it on the Qihai acupoint for regulating the spleen and stomach function and treating abdominal distension.

[0016] Preferably, the formula is: rhubarb (10%), raw atractylodes macrocephala (5%), semen cannabis (5%), for regulating the spleen and stomach function and treating dry stools.

[0017] Preferably, the formula is: rhubarb (10%), applicable to dry stools.

[0018] Preferably, use a nano-carrier to wrap and encapsulate the active ingredients of rhubarb (such as anthraquinones) in liposomes or polymer nanoparticles to improve skin permeability.

[0019] Preferably, add natural penetration enhancers (such as menthol, eucalyptus oil) or synthetic agents (azone) to the rhubarb powder to improve the drug absorption efficiency.

[0020] Preferably, add a small amount of protease inhibitor (such as leupeptin) to the rhubarb powder to reduce the degradation of the drug on the skin surface.

[0021] A method for using rhubarb powder acupoint application includes the following steps:

[0022] Environmental preparation: Select a clean and pollution-free environment to ensure aseptic operation;

[0023] Material preparation: Mix rhubarb powder (split according to different ratios) and auxiliary materials (raw atractylodes macrocephala powder, immature bitter orange powder, semen cannabis powder) according to the formula ratio, and use methods such as stirring or oscillation to evenly distribute the medicinal powder on the pre-prepared acupoint application paper to form a medicinal effect layer;

[0024] Device preparation: Prepare an acupoint application device made of high molecular materials. The device internally includes a drug layer and a protective layer, and use softstem pterygote mulberry as the core material to ensure the warmth and uniform diffusion of the medicinal powder;

[0025] Application and retention: Place the application device on the designated target acupoint, keep it fixed, and retain it for 4 to 6 hours. The operation should be gentle to avoid skin damage, especially when the operation is not proficient;

[0026] Post-treatment: After removing the application device, observe the local skin reaction. If there is any discomfort, stop using immediately, clean the skin, and provide appropriate care as needed.

[0027] Preferably, the preparation steps of the cnidium fruit extract are as follows: crush the cnidium fruit, sieve it through a 10 - 30 mesh sieve, soak it in an ethanol solution with a volume fraction of 75%, and then perform ultrasonic extraction for 1 hour each time, divided into 3 times at intervals. Adjust the speed to 7500 - 8500 rpm, centrifuge for 5 - 15 minutes, and filter with gauze to obtain the cnidium fruit extract.

[0028] Preferably, the specific process of the material preparation is as follows:

[0029] Step 1: Place the rhubarb powder in a clean container, slowly add an appropriate amount of water or glycerin, and heat it with a small fire until it is warm to boiling, about 5 minutes.

[0030] Step 2: Stir evenly. After the temperature is appropriate, add the powder of atractylodes macrocephala, immature bitter orange, and semen cannabis, and continue heating to keep it boiling for 10 minutes.

[0031] Step 3: When the temperature drops to an appropriate level, stop heating and wait for the medicinal juice to cool naturally.

[0032] Step 4: Dilute the medicinal material mixture to a uniform paste.

[0033] Step 5: Make the pill component into a pill shape and wrap it with gauze.

[0034] Compared with the prior art, the present invention has the following beneficial effects:

[0035] The present invention provides a rhubarb powder acupoint application and its usage method. Through scientific formula combination and application operation, it breaks the traditional application limitations and expands the rhubarb powder to the fields of treating various symptoms such as qi deficiency and weakness, abdominal distension, and dry stools. This innovation not only enriches the usage scenarios of rhubarb powder but also provides new ideas for its role in traditional Chinese medicine treatment. At the same time, in the form of acupoint application, patients can use it conveniently in daily life, thus realizing the lightweight and convenient management of diseases. Specific Embodiments

[0036] The following combines specific embodiments to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present invention.

[0037] The present invention provides a rhubarb powder acupoint application, the formula of which consists of the following raw materials: rhubarb, raw atractylodes macrocephala, immature bitter orange and semen cannabis. Through a specific formula combination and application operation, the effect of regulating the spleen and stomach and promoting digestion is achieved, and it includes:

[0038] For treating qi deficiency and weakness, 10% rhubarb powder + 15% raw atractylodes macrocephala powder;

[0039] For treating abdominal distension, 10% rhubarb + 10% immature bitter orange powder;

[0040] For treating dry stools, 10% rhubarb powder + 15% semen cannabis powder.

[0041] Example 1

[0042] For treating qi deficiency and weakness, constipation occurs after chemotherapy, stools are dry, once every 3 - 4 days, difficult to defecate each time, obvious fatigue, weakness in both lower limbs, no defecation in the past 5 days, symptoms are aggravated compared with before, accompanied by abdominal distension, stuffiness and pain, loss of appetite, poor spirit, and normal urination. The tongue is pale, the tongue coating is yellow and greasy, and the pulse is weak.

[0043] The formula is: rhubarb (10%), raw atractylodes macrocephala (5%), immature bitter orange (5%), semen cannabis (5%). Mix rhubarb, raw atractylodes macrocephala, immature bitter orange and semen cannabis to make rhubarb powder, cover the Zhongwan acupoint, and use it to regulate the function of the spleen and stomach and treat qi deficiency and weakness.

[0044] The specific steps are as follows:

[0045] 1. Select a clean and pollution - free environment.

[0046] 2. Prepare clean acupoint application paper.

[0047] 3. Mix rhubarb (10%), raw atractylodes macrocephala (5%), immature bitter orange (5%), semen cannabis (5%) according to the mass ratio, and prepare the powder according to the specified ratio.

[0048] 4. Evenly apply the powder on the Zhongwan acupoint, with a thickness of about 3 mm.

[0049] 5. Use wenshentongcao (extract of fructus cnidii) for treatment to prevent the loss of drug efficacy.

[0050] Example 2

[0051] For treating abdominal distension

[0052] The formula is: rhubarb (10%), raw atractylodes macrocephala (5%), immature bitter orange (5%). Mix rhubarb, raw atractylodes macrocephala and immature bitter orange to make rhubarb powder, cover the Qihai acupoint, and use it to regulate the function of the spleen and stomach and treat abdominal distension.

[0053] The specific steps are as follows:

[0054] 1. Select a suitable acupoint (Qihai acupoint).

[0055] 2. Mix according to the liquid medicine formula, and mix rhubarb (10%), raw atractylodes macrocephala (5%), and immature bitter orange (5%) into medicinal powder according to the mass ratio.

[0056] 3. Evenly apply it on the Qihai acupoint with a thickness of about 3 mm.

[0057] 4. Use the extract of cnidium monnieri to process to prevent the loss of medicinal efficacy.

[0058] 5. Retain for 4 - 6 hours.

[0059] Example 3

[0060] For treating dry stools, after eating a large amount of barbecue food, the stools have not been discharged for 3 days, are as hard as sheep dung balls, difficult to excrete, with dull pain and distension in the abdomen, palpable masses in the left and right lower abdomen, dry mouth, bad breath, obvious fear of heat, red tip of the tongue with cracks, less tongue coating, yellow and dry, and thready and unsmooth pulse.

[0061] The formula is: rhubarb (10%), raw atractylodes macrocephala (5%), and semen cannabis (5%), which is used to regulate the function of the spleen and stomach and treat dry stools.

[0062] In addition, other traditional Chinese medicines for moistening the intestines and relieving constipation, such as mirabilite, fructus cannabis, and immature bitter orange, can be combined to reduce the irritation of the single component of rhubarb and reduce the risk of long-term use; add sustained-release components, such as hydroxypropyl methylcellulose, to extend the drug action time and avoid the side effect of diarrhea.

[0063] The present invention also provides a method for using the rhubarb powder acupoint application, including the following steps:

[0064] Environmental preparation: Select a clean and pollution-free environment to ensure aseptic operation;

[0065] Material preparation: Mix rhubarb powder (split according to different ratios) and auxiliary materials (raw atractylodes macrocephala powder, immature bitter orange powder, semen cannabis powder) according to the formula ratio, and use methods such as stirring or oscillation to evenly distribute the medicinal powder on the pre-prepared acupoint application paper to form a medicinal efficacy layer;

[0066] Device preparation: Prepare an acupoint application device made of a polymer material. The device internally includes a drug layer and a protective layer, and use acanthopanax trifoliatus as the core material to ensure the warmth and uniform diffusion of the medicinal powder;

[0067] Retention of the application: Place the application device on the designated target acupoint, keep it fixed, and retain it for 4 to 6 hours. The operation should be gentle to avoid skin damage, especially when the operation is not proficient;

[0068] Post-treatment: After removing the application device, observe the local skin reaction. If there is any discomfort, stop using immediately, clean the skin, and perform appropriate care as needed.

[0069] Specifically, the specific process of material preparation is as follows:

[0070] Step 1: Place the rhubarb powder in a clean container, slowly add an appropriate amount of water or glycerin, and heat it with a small fire until it is warm to boiling for about 5 minutes.

[0071] Step 2: Stir evenly. After the temperature is appropriate, add the powder of Atractylodes macrocephala, Aurantii Fructus Immaturus, and Cannabis Seed, and continue heating to maintain a boiling state for 10 minutes;

[0072] Step 3: When the temperature drops to an appropriate level, stop heating and wait for the medicinal juice to cool naturally;

[0073] Step 4: Dilute the medicinal material mixture to a uniform paste;

[0074] Step 5: Shape the pill components into pill shapes and wrap them with gauze.

[0075] The present invention is an acupoint application agent of rhubarb powder. All four components in its formula have a strong diaphoretic effect, and the diaphoretic effect of this rhubarb is enhanced through appropriate compatibility. At the same time, the three components of Atractylodes macrocephala, Aurantii Fructus Immaturus, and Cannabis Seed respectively play the roles of promoting yang and warming, promoting diuresis and relieving distension, and lubricating the intestines and relieving constipation. Overall, it achieves the effects of warming yang and promoting qi, promoting qi movement and relieving distension, strengthening the spleen and stopping diarrhea.

[0076] The specific medication and process are shown in Table 1 below

[0077] Parameter Name Qi Deficiency and Weakness Abdominal Distension Constipation Parameter Name Powder Weight (g / h㎡) 0.08 0.05 0.07 Powder Weight (g / h㎡) Uniformity of Drug Efficacy Distribution Uniform Relatively Non-uniform Uniform Uniformity of Drug Efficacy Distribution Temperature (℃) 35-37 32-34 36-38 Temperature (℃) Local Temperature Change Rate 15％ 10％ 12％ Local Temperature Change Rate Drug Efficacy Retention Time (h) 4-6 5-6 4-5 Drug Efficacy Retention Time (h) Effective Stratification Thickness (mm) 3 3 3 Effective Stratification Thickness (mm) Powder Weight / Volume Ratio <![CDATA[20% (g / m 3 )]]> <![CDATA[30% (g / m 3 )]]> <![CDATA[25% (g / m 3 )]]> Powder Weight / Volume Ratio

[0078] Table 1

[0079] It should be noted that the formula of the present invention is based on the theory of the fourteen meridians in traditional Chinese medicine. The Shenque acupoint is located in the middle of the umbilicus, at the center of the umbilicus, and has the effect of regulating the stomach and intestines. Through scientific component compatibility, the following mechanisms are achieved:

[0080] 1. Taking warming yang and regulating qi as the main purpose, it plays a role in regulating the functions of the spleen and stomach.

[0081] 2. Secondly, clearing heat and promoting diuresis is used to treat dry stools and internal damp-heat syndrome.

[0082] 3. Ensure the stability of the effective components through the pretreatment of the extract of Cnidium monnieri.

[0083] 4. The main purpose of treating qi deficiency and weakness is to assist.

[0084] 5. The main purpose of treating abdominal distension is to promote the excretion of internal damp-heat through the compatibility of rhubarb and Aurantii Fructus Immaturus.

[0085] 6. The main purpose of treating dry stools is to help relieve the symptoms through the spleen-strengthening effect of Cannabis Seed.

[0086] 7. When all formulations are in use, the principle of from the inside to the outside and from the surface to the interior must be followed.

[0087] Rationality and mechanism analysis of formulation compatibility Rationality of formulation compatibility:

[0088] Rhubarb (10%): Responsible for clearing heat and promoting diuresis, and regulating the functions of the spleen and stomach, which is the core dosage of the present invention.

[0089] Raw Atractylodes macrocephala (5%): Raw Atractylodes macrocephala has a good effect of strengthening the stomach and assisting yang, enhancing the yang-warming effect of rhubarb, and at the same time avoiding the symptoms of physical weakness caused by simple yang-warming.

[0090] Fructus Aurantii Immaturus (5%): Fructus Aurantii Immaturus can effectively enhance the dampness-eliminating effect of rhubarb in the present invention, and at the same time has a certain spleen-strengthening effect.

[0091] Fructus Cannabis (5%): Fructus Cannabis can both warm and dredge the liver and gallbladder and promote qi and strengthen the spleen, playing a good auxiliary role.

[0092] In the preparation process of the present invention, the preparation of Cnidium monnieri extract adopts ultrasonic extraction technology, which crushes, extracts and ultrasonically accelerates the removal of impurities from Cnidium monnieri, and maximally retains the active ingredients of traditional Chinese medicine in Cnidium monnieri to ensure the release of drug efficacy.

[0093] In addition, it should be understood that although this specification is described according to the embodiments, not every embodiment only contains an independent technical solution. This narrative way of the specification is only for clarity. Those skilled in the art should regard the specification as a whole, and the technical solutions in each embodiment can also be appropriately combined to form other embodiments that can be understood by those skilled in the art.

Claims

1. A rhubarb powder acupoint application, characterized in that, The formula consists of the following raw materials: rhubarb, raw atractylodes macrocephala, immature bitter orange, and semen cannabis. Through specific formula combinations and application operations, it achieves the effects of regulating the spleen and stomach and promoting digestion, including: For treating qi deficiency and weakness, 10% rhubarb powder + 15% raw atractylodes macrocephala powder; For treating abdominal distension, 10% rhubarb + 10% immature bitter orange powder; For treating dry stools, 10% rhubarb powder + 15% semen cannabis powder.

2. The acupoint application with rhubarb powder according to claim 1, wherein The formula is: rhubarb (10%), raw atractylodes macrocephala (5%), immature bitter orange (5%), semen cannabis (5%). Mix rhubarb, raw atractylodes macrocephala, immature bitter orange, and semen cannabis to make rhubarb powder, and cover the Zhongwan acupoint for regulating the spleen and stomach function and treating qi deficiency and weakness.

3. The Dahuang powder acupoint application according to claim 1, characterized in that The formula is: rhubarb (10%), raw atractylodes macrocephala (5%), immature bitter orange (5%). Mix rhubarb, raw atractylodes macrocephala, and immature bitter orange to make rhubarb powder, and cover the Qihai acupoint for regulating the spleen and stomach function and treating abdominal distension.

4. The rhubarb powder acupoint application according to claim 1, wherein The formula is: rhubarb (10%), raw atractylodes macrocephala (5%), semen cannabis (5%), for regulating the spleen and stomach function and treating dry stools.

5. The Dahuang powder acupoint application according to claim 1, characterized in that, The formula is: rhubarb (10%), applicable to dry stools.

6. The method of using a rhubarb powder acupoint application according to any one of claims 1-5, characterized in that, It includes the following steps: Environmental preparation: Select a clean and pollution-free environment to ensure aseptic operation; Material preparation: Mix rhubarb powder (split according to different ratios) and auxiliary materials (raw atractylodes macrocephala powder, immature bitter orange powder, semen cannabis powder) according to the formula ratio, and use methods such as stirring or oscillation to evenly distribute the medicinal powder on the pre-prepared acupoint application paper to form a medicinal effect layer; Device preparation: Prepare an acupoint application device made of a polymer material. The device internally contains a drug layer and a protective layer, and use litsea cubeba as the core material to ensure the warming and uniform diffusion of the medicinal powder; Application and retention: Place the application device on the designated target acupoint, keep it fixed, and retain it for 4 to 6 hours. During the operation, the movements should be gentle to avoid skin damage, especially when the operation is not proficient; Post-treatment: After removing the application device, observe the local skin reaction. If there is discomfort, stop using immediately, clean the skin, and perform appropriate care as needed.

7. The method for using the rhubarb powder acupoint application according to claim 6, characterized in that: The specific process of the material preparation process is as follows: Step 1: Place rhubarb powder in a clean container, slowly add an appropriate amount of water or glycerin, and heat it with a small fire until it is warm to boiling for about 5 minutes. Step 2: Stir evenly. After the temperature is appropriate, add raw atractylodes macrocephala powder, immature bitter orange powder, and semen cannabis powder, and continue to heat, keeping it in a boiling state for 10 minutes; Step 3: When the temperature drops to an appropriate level, stop heating and wait for the medicinal juice to cool naturally; Step 4: Dilute the medicinal material mixture to a uniform paste; Step 5: Make the pill component into a pill shape and wrap it with gauze.