Cough-relieving paste mainly prepared from momordica grosvenori, liquorice and lily and preparation method of cough-relieving paste

A seven-ingredient stop cough lozenge formulation enhances extraction and prevents separation, offering effective cough relief and throat comfort through a three-step boiling and high-pressure homogenization process.

CN120305351APending Publication Date: 2025-07-15YUNGUITONG (GUANGXI) TECHNOLOGY CO LTD
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Patent Information

Application Number
CN202510771304.6
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-06-10
Publication Date
2025-07-15

AI Technical Summary

Technical Problem

In the prior art, the decoction process of Luohan Fruit, licorice and lily cough suppressant paste has not optimized the dissolution rate of active ingredients, and there is a problem of paste stratification.

Method used

The three-stage decoction method is used to combine 150MPa ultra-high pressure homogenization technology, and brown sugar dissolution and lily ultrafine powder are added to increase the content of amygdalin to 12.1mg/g to solve the problem of paste stratification.

Benefits of technology

It significantly improves the dissolution rate of the active ingredient of the cough suppressant cream, ensures the uniformity of the cream, and achieves an effective relief effect on cough and sore throat.

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Abstract

The invention discloses a formula and a preparation method of cough-relieving paste mainly prepared from momordica grosvenori, liquorice and lily. The cough-relieving paste is prepared from seven traditional Chinese medicines such as momordica grosvenori and the like which are used for preparing the paste according to a conventional proportion. The cough relieving paste is brownish black; the health-care product is mainly used for treating sore throat and the like, and has the effects of clearing heat, moistening lung, relieving cough and sore throat, tonifying qi and promoting the secretion of saliva or body fluid. The product has the effects of relieving throat discomfort and bronchial discomfort caused by smoking and diseases and benefiting the throat.
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Description

Technical Field

[0001] The present invention is mainly applicable to cough-relieving health foods, and particularly relates to a cough-relieving paste mainly composed of Momordica grosvenori, Glycyrrhiza uralensis, and Lilium brownii, and a preparation method thereof. Background Art

[0002] The prior art CN102178695A discloses a cough-relieving paste containing Momordica grosvenori, Glycyrrhiza uralensis, and Lilium brownii, but its decocting process does not optimize the dissolution rate of active ingredients and does not solve the problem of paste stratification. Summary of the Invention

[0003] The purpose of the present invention is to provide a cough-relieving paste mainly composed of Momordica grosvenori, Glycyrrhiza uralensis, and Lilium brownii, and a preparation method thereof. It is cheap and has a simple processing technology. During its remanufacturing process, 7 core components are added, which is applicable to coughs and sore throats and has the effects of clearing away heat and moistening the lungs, helping to relieve coughs, sore throats, replenishing qi and promoting fluid production, etc.

[0004] The technical solution of the present invention: A cough-relieving paste mainly composed of Momordica grosvenori, Glycyrrhiza uralensis, and Lilium brownii, and a preparation method thereof include processing and adding effective ingredients such as Momordica grosvenori, Glycyrrhiza uralensis, Lilium brownii, Fritillaria cirrhosa, Eriobotrya japonica, Chinese date, Chrysanthemum morifolium, and brown sugar.

[0005] The above-mentioned Momordica grosvenori 35 - 45 g, Glycyrrhiza uralensis 20 - 30 g, Lilium brownii 15 - 25 g, Fritillaria cirrhosa 10 - 15 g, Eriobotrya japonica 20 - 30 g, Chinese date 20 - 25 g, Chrysanthemum morifolium 10 - 15 g, brown sugar 250 - 300 g, and an appropriate amount of purified water; 2. The method for preparing the cough-relieving paste according to claim 1, comprising: (1) Soak Momordica grosvenori, Glycyrrhiza uralensis, Lilium brownii, Fritillaria cirrhosa, Eriobotrya japonica, Chinese date, and Chrysanthemum morifolium in 8 times the amount of water for two hours; (2) Decoct in three stages: the first decoction at 100°C for 40 min → the second decoction at 90°C for 30 min → the third decoction at 80°C for 20 min; (3) Combine the decocted liquid and subject it to ultra-high pressure homogenization at 150 MPa, and the content of amygdalin rises to 12.1 mg / g (HPLC method); (4) Concentrate to a specific gravity of 1.25 - 1.30 at 60°C and add brown sugar to dissolve; (5) Add lily ultrafine powder (D90 ≤ 50 μm) in three portions at 50 - 60°C, and stir for 5 minutes each time.

[0006] Practical Application of the Present Invention: After being applied, 30 patients with throat discomfort caused by long-term smoking, coughing, etc. take about 5 ml of the cough-relieving paste mainly composed of Momordica grosvenori, Glycyrrhiza uralensis, and Lilium brownii and wash it down with warm water, then the cough can be relieved and the throat feels comfortable, and the average cough frequency of 30 patients decreases.

[0007] Case Analysis: Case 1: Li XX, male, 16 years old, non-smoker, with a long-term cough. After taking 5 ml of the cough-relieving cream mixed with warm water, the cough symptoms were relieved.

[0008] Case 2: Tang XX, female, 20 years old, with long-term throat discomfort accompanied by cough. After taking 5 ml of the cough-relieving cream mixed with warm water, the cough symptoms were relieved.

[0009] Case 3: Zhang XX, male, 37 years old, with a long-term cough. After taking 5 ml of the cough-relieving cream mixed with warm water, the cough symptoms were relieved.

[0010] Case 4: Ning XX, female, 12 years old, with breathing discomfort. After taking it, the cough symptoms were relieved.

[0011] The advantages of the present invention are as follows: Seven core components such as Siraitia grosvenorii are added to the cream in the present invention. The present invention is mainly applicable to health products for cough patients, and has the effects of clearing away heat and moistening the lungs, helping to relieve cough, sore throat, and replenishing qi and promoting fluid production. It can relieve cough for the discomfort of the throat and bronchus caused by smoking and diseases. Specific embodiments

[0012] The following gives an embodiment of the present invention in combination with the process of a cough-relieving cream mainly composed of Siraitia grosvenorii, licorice, and lily, to further illustrate the process manufacturing plan.

[0013] Embodiment: The processing of a cough-relieving cream mainly composed of Siraitia grosvenorii, licorice, and lily and its preparation method are as follows: 1. Composition: 35 - 45 g of Siraitia grosvenorii, 20 - 30 g of licorice, 15 - 25 g of lily, 10 - 15 g of Fritillaria cirrhosa, 20 - 30 g of Eriobotrya japonica leaves, 20 - 25 g of red dates, 10 - 15 g of chrysanthemum, 250 - 300 g of brown sugar, and an appropriate amount of purified water.

[0014] 2. Preparation method: 2. The method for preparing the cough-relieving cream as claimed in claim 1, comprising: (1) Soak Siraitia grosvenorii, licorice, lily, Fritillaria cirrhosa, Eriobotrya japonica leaves, red dates, and chrysanthemum in 8 times the amount of water for two hours; (2) Three-stage decoction: First decoction at 100 °C for 40 min → Second decoction at 90 °C for 30 min → Third decoction at 80 °C for 20 min; (3) Combine the decoction liquids and homogenize them under 150 MPa ultra-high pressure, and the content of amygdalin rises to 12.1 mg / g (HPLC method); (4) Concentrate to a specific gravity of 1.25 - 1.30 at 60 °C, and add brown sugar to dissolve; (5) Add lily ultrafine powder (D90 ≤ 50 μm) in three portions at 50 - 60 °C, and stir for 5 minutes each time.

[0015] Detection results of amygdalin content: Before homogenization: 6.8 ± 0.2 mg / g After homogenization at 150 MPa: 12.1 ± 0.3 mg / g (Data source: TJ2023-0851 test report, method according to General Chapter 0512 of Chinese Pharmacopoeia 2020 Edition).

Claims

1. A cough-relieving plaster, characterized in that It is made from the following raw materials in the following weight ratios: 35 - 45 g of Siraitia grosvenorii, 20 - 30 g of liquorice, 15 - 25 g of lily, 10 - 15 g of Fritillaria cirrhosa, 20 - 30 g of Eriobotrya japonica leaves, 20 - 25 g of red dates, 10 - 15 g of chrysanthemum, 250 - 300 g of brown sugar, and an appropriate amount of purified water.

2. The method for preparing the cough-relieving paste as claimed in claim 1, comprising: (1) Soak Siraitia grosvenorii, liquorice, lily, Fritillaria cirrhosa, Eriobotrya japonica leaves, red dates, and chrysanthemum in 8 times the amount of water for two hours; (2) Decoct in three stages: the first decoction at 100 °C for 40 min → the second decoction at 90 °C for 30 min → the third decoction at 80 °C for 20 min; (3) Combine the decocted liquid and subject it to ultra-high pressure homogenization at 150 MPa, and the content of amygdalin rises to 12.1 mg / g (HPLC method); (4) Concentrate to a specific gravity of 1.25 - 1.30 at 60 °C and add brown sugar to dissolve; (5) Add lily ultrafine powder (D90 ≤ 50 μm) in three portions at 50 - 60 °C, and stir for 5 minutes each time.

Citation Information

Patent Citations

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