Complete set of hydrogel particle production equipment and production method

Abstract

The invention belongs to the field of hydrogel production, and relates to a complete set of hydrogel particle production equipment and a production method, the complete set of hydrogel particle production equipment comprises: a data acquisition module for acquiring oxygen concentration data and humidity data; the oxygen analysis module is used for determining whether the single freezing and thawing cycle is qualified or not based on the single-cycle oxygen concentration difference of the oxygen concentration data; the data processing module is used for determining whether the structure of the hydrogel is stable or not based on the concentration difference change characterization parameters after the three times of freezing and thawing cycles, and determining and adjusting the freezing duration or the drying duration according to the difference value; the humidity analysis module is used for determining whether the humidity uniformity is qualified or not based on the humidity gradient value of the humidity data, and determining an environment box with unqualified humidity according to the humidity change rate of the humidity data; the data adjusting module is used for determining and adjusting the temperature based on the ratio of the humidity change rate to the preset humidity change rate or determining and adjusting the fan rate based on the relative difference between the humidity change rate and the preset humidity change rate, and the stability of the hydrogel structure is improved.

Description

Technical Field

[0001] The present invention belongs to the field of hydrogel production, and relates to a complete set of production equipment and production method for hydrogel particles. Background Art

[0002] In order to effectively reduce the endogenous pollution load of river channels, so as to achieve the purpose of improving water quality and habitat and promoting ecological restoration of water bodies, functional materials with slow-release oxygen, adsorption, and catalytic oxidation-reduction functions are organically combined, and a multifunctional water body ecological restoration hydrogel oxygen-releasing material is designed and synthesized. A multifunctional water body ecological restoration oxygen-releasing material based on polyvinyl alcohol hydrogel is synthesized by the freeze-thaw cross-linking method. This material has a strong decontamination effect and less environmental impact.

[0003] Chinese Patent Application Publication No.: CN103788385A discloses a method for preparing hydrogel photonic crystal particles by spray drying, including: dispersing monodisperse colloidal particles into water to prepare a monodisperse colloidal particle emulsion; preparing a hydrogel solution, and adding the hydrogel solution to the monodisperse colloidal particle emulsion to obtain a mixed emulsion; pumping the mixed emulsion into a spray drying device and obtaining hydrogel photonic crystal particles through spray drying. In this application, water is used as a solvent in the mixed emulsion used as the spray drying raw material, which reduces the operation requirements, has high safety, and avoids environmental pollution caused by the use of organic solvents; because a hydrogel is introduced into the mixed emulsion, the prepared hydrogel photonic crystal particles have biocompatibility and biodegradability characteristics, and the hydrogel material is easy to modify, making the application of hydrogel photonic crystals more extensive; in this application, since hydrogel photonic crystal particles are prepared by spray drying, mass production can be achieved, improving production efficiency.

[0004] However, the following problems exist in the prior art: The prior art does not carry out refined treatment on the excessive oxidation and uneven humidity during the freeze-thaw process of the hydrogel, resulting in the instability of the hydrogel structure, and thus the problem of low stability of the hydrogel structure. Summary of the Invention

[0005] Therefore, the present invention provides a complete set of production equipment and production method for hydrogel particles to overcome the problem that the prior art does not carry out refined treatment on the excessive oxidation and uneven humidity during the freeze-thaw process of the hydrogel, resulting in the instability of the hydrogel structure, and thus the problem of low stability of the hydrogel structure.

[0006] To achieve the above object, the present invention provides a complete set of production equipment for hydrogel particles, including: An environmental chamber, which includes a freezing chamber and a drying chamber, A detection mechanism, which includes an oxygen detection device for detecting the indoor oxygen concentration and a humidity detection device for detecting the indoor humidity, respectively arranged in the freezing chamber and the drying chamber; A control mechanism, which is arranged inside the environmental chamber, includes: A data acquisition module, which is used to obtain the oxygen concentration data and humidity data detected by the detection mechanism; An oxygen analysis module, which is connected to the data acquisition module and is used to determine whether a single freeze-thaw cycle is qualified based on the single-cycle oxygen concentration difference of the oxygen concentration data; A data processing module, which is connected to the oxygen analysis module and is used to determine whether the structure of the hydrogel is stable based on the change characterization parameter of the concentration difference after three freeze-thaw cycles under the condition that a single freeze-thaw cycle is qualified, and to determine whether to adjust the freezing duration or drying duration according to the difference between the change characterization parameter of the concentration difference and the preset change characterization parameter of the concentration difference; A humidity analysis module, which is connected to the data processing module and is used to determine whether the humidity uniformity of a single freeze-thaw cycle is qualified based on the humidity gradient value of the humidity data under the condition that a single freeze-thaw cycle is unqualified, and to determine the environmental chamber with unqualified humidity according to the humidity change rate of the humidity data; A data adjustment module, which is connected to the humidity analysis module and is used to determine whether to adjust the temperature of the freezing chamber or the drying chamber based on the ratio of the humidity change rate to the preset humidity change rate or to determine whether to adjust the fan speed based on the relative difference between the humidity change rate and the preset humidity change rate.

[0007] Further, the oxygen analysis module determines that a single freeze-thaw cycle is qualified based on the comparison result that the single-cycle oxygen concentration difference of the oxygen concentration data is less than or equal to the preset single-cycle oxygen concentration difference, and determines that the structure of the hydrogel is stable according to the comparison result that the change characterization parameter of the concentration difference is less than or equal to the preset change characterization parameter of the concentration difference.

[0008] Further, the oxygen analysis module determines that a single freeze-thaw cycle is qualified based on the comparison result that the single-cycle oxygen concentration difference of the oxygen concentration data is less than or equal to the preset single-cycle oxygen concentration difference, and determines that the structure of the hydrogel is unstable according to the comparison result that the change characterization parameter of the concentration difference is greater than the preset change characterization parameter of the concentration difference.

[0009] When the data processing module determines that the structure of the hydrogel is unstable, the process of adjusting the freezing duration or drying duration includes: Subtracting the change characterization parameter of the concentration difference from the preset change characterization parameter of the concentration difference; Based on the comparison result that the difference is less than or equal to the preset difference, it is determined to increase the freezing duration of the freezing chamber with a preset freezing time adjustment coefficient; Based on the comparison result that the difference is greater than the preset difference, it is determined to increase the drying duration of the drying chamber with a preset drying time adjustment coefficient.

[0010] Further, the oxygen analysis module determines that a single freeze-thaw cycle is unqualified based on the comparison result that the oxygen concentration difference in a single cycle of oxygen concentration data is greater than a preset single-cycle oxygen concentration difference, and determines that the humidity uniformity of a single freeze-thaw cycle is unqualified based on the comparison result that the humidity gradient value of the humidity data is greater than a humidity gradient threshold.

[0011] Further, under the condition that the humidity analysis module determines that the humidity uniformity of a single freeze-thaw cycle is unqualified, it determines that the humidity of the freezer or the drying chamber is unqualified based on the comparison result that the humidity change rate of the humidity data is less than or equal to a preset humidity change rate.

[0012] Further, under the condition that the humidity analysis module determines that the humidity uniformity of a single freeze-thaw cycle is unqualified, it determines that the humidity of both the freezer and the drying chamber is unqualified based on the comparison result that the humidity change rate of the humidity data is greater than a preset humidity change rate.

[0013] Further, the process of the data adjustment module adjusting the temperature of the freezer or the drying chamber under the condition that it determines that the humidity of the freezer or the drying chamber is unqualified includes: Dividing the humidity change rate by a preset humidity change rate; Based on the comparison result that the ratio is less than or equal to a preset ratio, it determines to reduce the freezing temperature of the freezer by a preset freezing temperature adjustment coefficient; Based on the comparison result that the ratio is greater than a preset ratio, it determines to increase the drying temperature of the drying chamber by a preset drying temperature adjustment coefficient.

[0014] Further, the process of the data adjustment module adjusting the fan speed under the condition that it determines that the humidity of both the freezer and the drying chamber is unqualified includes: Taking the relative difference between the humidity change rate and a preset humidity change rate; Setting a number of adjustment coefficients corresponding to the respective relative differences; Increasing the fan speed based on a number of said adjustment coefficients; Setting the corresponding relationship between the respective relative differences and the increased fan speed to adjust the fan speed.

[0015] On the other hand, the present invention also provides a complete set of production methods for hydrogel particles, including: Obtaining oxygen concentration data and humidity data detected by a testing agency; Determining whether a single freeze-thaw cycle is qualified based on the oxygen concentration difference in a single cycle of the oxygen concentration data; Under the condition that a single freeze-thaw cycle is qualified, determining whether the structure of the hydrogel is stable based on the concentration difference change characterization parameter after three freeze-thaw cycles, and determining to adjust the freezing duration or the drying duration according to the difference between the concentration difference change characterization parameter and a preset concentration difference change characterization parameter; Based on the condition that a single freeze-thaw cycle is unqualified, determine whether the humidity uniformity of a single freeze-thaw cycle is qualified according to the humidity gradient value of the humidity data, so as to determine the environmental chamber with unqualified humidity according to the humidity change rate of the humidity data; Determine to adjust the temperature of the freezer or drying chamber based on the ratio of the humidity change rate to the preset humidity change rate, or determine to adjust the fan speed based on the relative difference between the humidity change rate and the preset humidity change rate.

[0016] Compared with the prior art, the beneficial effects of the present invention are as follows: the present invention injects the water dispersion liquid into the mold through the glue injection mechanism, the pushing mechanism sequentially sends the mold into the freezer and the drying chamber for freeze-thaw cycle treatment, the pulling mechanism pulls out the treated mold, and the detection mechanism monitors the oxygen concentration and humidity data in real time to judge whether the freeze-thaw cycle is qualified and whether the hydrogel structure is stable. If an abnormality is found, the freezing time, drying time, temperature of a single chamber or fan speed is adjusted to optimize the working state of the environmental chamber, improve the freeze-thaw cycle treatment effect, ensure the stability of the hydrogel structure, and improve the efficiency and quality of hydrogel preparation.

[0017] Furthermore, the present invention compares the oxygen concentration difference of a single cycle with the oxygen concentration difference of a single cycle, and when a single freeze-thaw cycle is qualified, compares the characterization parameter of the concentration difference change after three freeze-thaw cycles with the preset characterization parameter of the concentration difference change, which improves the quality of the hydrogel, enhances the production efficiency, and thus improves the accuracy and reliability of the freeze-thaw cycle treatment.

[0018] Furthermore, when the hydrogel structure is unstable, the present invention adjusts the freezing time or drying time according to the difference between the characterization parameter of the concentration difference change and the preset characterization parameter of the concentration difference change. When a single freeze-thaw cycle is unqualified, it judges the humidity uniformity according to the humidity gradient value, and when it is unqualified, it determines the humidity unqualified chamber according to the humidity change rate, which improves the accuracy and pertinence of the preparation and avoids affecting the performance and quality of the hydrogel due to the problem of uneven humidity.

[0019] Furthermore, when the humidity of a single chamber is unqualified, the present invention adjusts the freezing temperature or drying temperature according to the ratio of the humidity change rate to the preset humidity change rate. When the humidity of both chambers is unqualified, it adjusts the fan speed according to the relative difference between the humidity change rate and the preset humidity change rate, reduces the influence of humidity fluctuation on the performance of the hydrogel, and improves the stability and consistency of the hydrogel quality. Description of the Drawings

[0020] Figure 1 It is a schematic structural diagram of the complete set of hydrogel particle production equipment according to the embodiment of the present invention.

[0021] Figure 2 It is a flowchart of the complete set of hydrogel particle production method according to the embodiment of the present invention.

[0022] Figure 3 It is a flowchart for determining whether a single freeze-thaw cycle is qualified in an embodiment of the present invention.

[0023] Figure 4 It is a flowchart for determining whether the structure of the hydrogel is stable in an embodiment of the present invention.

[0024] In the figure, 1 is a freezing chamber; 2 is a drying chamber; 3 is a glue injection mechanism; 401 is a first pushing unit; 402 is a second pushing unit; 501 is a first pulling unit; 502 is a second pulling unit; 6 is an observation window; 701 is an oxygen detection device; 702 is a humidity detection device. Detailed implementation manners

[0025] In order to make the objectives and advantages of the present invention clearer and more understandable, the present invention will be further described below in conjunction with embodiments; it should be understood that the specific embodiments described herein are only used to explain the present invention and are not used to limit the present invention.

[0026] The preferred embodiments of the present invention will be described below with reference to the accompanying drawings. Those skilled in the art should understand that these embodiments are only used to explain the technical principles of the present invention and do not limit the protection scope of the present invention.

[0027] It should be noted that the data in this embodiment are all obtained through comprehensive analysis and evaluation of the historical test data and corresponding historical test results of the present invention in the three months before this test. Those skilled in the art can understand that the determination method of the present invention for a single above parameter can be to select the value with the highest proportion according to the data distribution as the preset standard parameter, use weighted summation to obtain the value as the preset standard parameter, substitute each historical data into a specific formula and use the value obtained by this formula as the preset standard parameter or other selection methods, as long as it meets the requirement that the present invention can clearly define different specific situations in the single determination process through the obtained values.

[0028] Please refer to Figure 1 As shown, it is a schematic structural diagram of a complete set of production equipment for hydrogel particles in an embodiment of the present invention.

[0029] An environmental chamber, which includes a freezing chamber 1 and a drying chamber 2; A glue injection mechanism 3, which is arranged on the left side of the freezing chamber 1 to inject a water dispersion into a plurality of molds; A pushing mechanism, which includes a first pushing unit 401 arranged on the left side of the glue injection mechanism 3 to send the molds after glue injection into the freezing chamber 1, and a second pushing unit 402 arranged on the left side of the drying chamber 2 to send the frozen molds into the drying chamber 2; A pulling-out mechanism, which includes a first pulling-out unit 501 arranged on the right side of the freezer 1 for pulling out the frozen mold, and a second pulling-out unit 502 arranged on the right side of the drying chamber 2 for pulling out the dried mold; An observation mechanism, which includes observation windows 6 respectively arranged on both sides of the freezer 1 and the drying chamber 2 for observing the samples in the chambers; A detection mechanism, which includes oxygen detection devices 701 respectively arranged in the freezer 1 and the drying chamber 2 near the observation mechanism for detecting the oxygen concentration in the chambers, and humidity detection devices 702 arranged away from the oxygen detection devices 701 for detecting the humidity in the chambers; A control mechanism, which is arranged in the environmental chamber and includes, A data acquisition module, which is used to obtain the oxygen concentration data and humidity data detected by the detection mechanism; An oxygen analysis module, which is connected to the data acquisition module and is used to determine whether a single freeze-thaw cycle is qualified based on the single-cycle oxygen concentration difference of the oxygen concentration data; A data processing module, which is connected to the oxygen analysis module and is used to determine whether the structure of the hydrogel is stable based on the concentration difference change characterization parameter after three freeze-thaw cycles under the condition that a single freeze-thaw cycle is qualified, and to determine whether to adjust the freezing duration or the drying duration according to the difference between the concentration difference change characterization parameter and the preset concentration difference change characterization parameter; A humidity analysis module, which is connected to the data processing module and is used to determine whether the humidity uniformity of a single freeze-thaw cycle is qualified based on the humidity gradient value of the humidity data under the condition that a single freeze-thaw cycle is unqualified, and to determine the environmental chamber with unqualified humidity according to the humidity change rate of the humidity data; A data adjustment module, which is connected to the humidity analysis module and is used to determine whether to adjust the temperature of the freezer or the drying chamber based on the ratio of the humidity change rate to the preset humidity change rate or to determine whether to adjust the fan speed based on the relative difference between the humidity change rate and the preset humidity change rate.

[0030] In the embodiment of the present invention, the oxygen detection device is an electrochemical oxygen sensor, and the humidity detection device is a capacitive humidity sensor. Specifically, there is no limitation, as long as the oxygen concentration data and humidity data can be measured.

[0031] In the embodiment of the present invention, the freezing duration range of the freezer is 2.8 h to 3.2 h, preferably 3 h, the freezing temperature range is -22°C to -18°C, preferably -20°C, and the freezing rate range is 180 rpm to 220 rpm, preferably 200 rpm. The above parameters are obtained under the condition of taking the average value of the freezing parameters of the freezer in several previous experiments with qualified hydrogel preparation stability. The freezing parameters are the freezing duration, the freezing temperature, and the freezing rate.

[0032] In the embodiments of the present invention, the drying duration of the drying chamber ranges from 3.7 h to 4.3 h, preferably 4 h, the drying temperature ranges from 24 °C to 26 °C, preferably 25 °C, and the drying rate ranges from 270 rpm to 230 rpm, preferably 300 rpm. The above parameters are obtained under the condition of taking the average value of the drying parameters of the drying chamber in several historical experiments with qualified hydrogel preparation stability. The drying parameters are the drying duration, drying temperature, and drying rate.

[0033] Please refer to Figure 2 as shown, which is a flowchart of the complete set of production methods for hydrogel particles in the embodiments of the present invention.

[0034] On the other hand, the present invention also provides a complete set of production methods for hydrogel particles, including: Step S1, obtaining the oxygen concentration data and humidity data detected by the detection mechanism; Step S2, determining whether a single freeze-thaw cycle is qualified based on the single-cycle oxygen concentration difference of the oxygen concentration data; Step S3, under the condition that a single freeze-thaw cycle is qualified, determining whether the structure of the hydrogel is stable according to the concentration difference change characterization parameter after three freeze-thaw cycles, and determining to adjust the freezing duration or drying duration according to the difference between the concentration difference change characterization parameter and the preset concentration difference change characterization parameter; Step S4, under the condition that a single freeze-thaw cycle is unqualified, determining whether the humidity uniformity of a single freeze-thaw cycle is qualified according to the humidity gradient value of the humidity data, and determining the environmental chamber with unqualified humidity according to the humidity change rate of the humidity data; Step S5, determining to adjust the temperature of the freezing chamber or drying chamber based on the ratio of the humidity change rate to the preset humidity change rate or determining to adjust the fan speed based on the relative difference between the humidity change rate and the preset humidity change rate.

[0035] Specifically, the present invention injects the aqueous dispersion into the mold through the injection mechanism, the pushing mechanism sequentially sends the mold into the freezing chamber and the drying chamber for freeze-thaw cycle treatment, the pulling mechanism pulls out the treated mold, and the detection mechanism monitors the oxygen concentration and humidity data in real time to determine whether the freeze-thaw cycle is qualified and whether the structure of the hydrogel is stable. If an abnormality is found, the freezing duration, drying duration, temperature of a single chamber, or fan speed is adjusted to optimize the working state of the environmental chamber, improve the freeze-thaw cycle treatment effect, ensure the stability of the hydrogel structure, and improve the efficiency and quality of hydrogel preparation.

[0036] Please refer to Figure 3 as shown, which is a flowchart of determining whether a single freeze-thaw cycle is qualified in the embodiments of the present invention.

[0037] Specifically, the oxygen analysis module determines whether a single freeze-thaw cycle is qualified according to the comparison result between the oxygen concentration difference in a single cycle of the oxygen concentration data and the preset oxygen concentration difference in a single cycle; If the oxygen concentration difference in a single cycle is less than or equal to the preset oxygen concentration difference in a single cycle, it is determined that the single freeze-thaw cycle is qualified; If the oxygen concentration difference in a single cycle is greater than the preset oxygen concentration difference in a single cycle, it is determined that the single freeze-thaw cycle is unqualified.

[0038] In the embodiment of the present invention, the preset oxygen concentration difference in a single cycle takes a value of 0.5%. The preset oxygen concentration difference in a single cycle is obtained by taking the maximum value of the oxygen concentration differences in a single cycle of several qualified historical single freeze-thaw cycles. However, the above value is not limited to this, and those skilled in the art can also adjust this value according to actual needs.

[0039] During implementation, the oxygen concentration difference in a single cycle is the absolute value of the difference between the oxygen concentration at the end of a single cycle and the oxygen concentration at the beginning of a single cycle.

[0040] Please refer to Figure 4 as shown, which is a flowchart for determining whether the structure of the hydrogel is stable in the embodiment of the present invention.

[0041] Specifically, under the condition that the data processing module determines that a single freeze-thaw cycle is qualified, it determines whether the structure of the hydrogel is stable according to the comparison result between the concentration difference change characterization parameter after three freeze-thaw cycles and the preset concentration difference change characterization parameter; If the concentration difference change characterization parameter is less than or equal to the preset concentration difference change characterization parameter, it is determined that the structure of the hydrogel is stable; If the concentration difference change characterization parameter is greater than the preset concentration difference change characterization parameter, it is determined that the structure of the hydrogel is unstable.

[0042] In the embodiment of the present invention, the preset concentration difference change characterization parameter takes a value of 0.25. The preset concentration difference change characterization parameter is obtained by taking the maximum value of the concentration difference change characterization parameters of the structures of several qualified historical hydrogels. However, the above value is not limited to this, and those skilled in the art can also adjust this value according to actual needs.

[0043] During implementation, the concentration difference change characterization parameter is the result of dividing the absolute value of the difference between the oxygen concentration difference in the third cycle and the oxygen concentration difference in the first cycle by the oxygen concentration difference in the first cycle.

[0044] Specifically, in the present invention, by comparing the oxygen concentration difference in a single cycle with the oxygen concentration difference in a single cycle, and when the single freeze-thaw cycle is qualified, comparing the change characterization parameter of the concentration difference after three freeze-thaw cycles with the preset change characterization parameter of the concentration difference, the quality of the hydrogel is improved, the production efficiency is enhanced, and thus the accuracy and reliability of the freeze-thaw cycle treatment are improved.

[0045] Specifically, under the condition that the data processing module determines that the structure of the hydrogel is unstable, it determines to adjust the freezing duration or the drying duration according to the comparison result between the difference between the change characterization parameter of the concentration difference and the preset change characterization parameter of the concentration difference and the preset difference.

[0046] If the difference is less than or equal to the preset difference, it is determined to increase the freezing duration of the freezer to the corresponding value with a preset freezing time adjustment coefficient of 1.05; If the difference is greater than the preset difference, it is determined to reduce the drying duration of the drying chamber to the corresponding value with a preset drying time adjustment coefficient of 0.98; The difference is the difference between the change characterization parameter of the concentration difference and the preset change characterization parameter of the concentration difference.

[0047] In the embodiment of the present invention, the preset difference takes a value of 0.12, but the above value is not limited to this, and those skilled in the art can also adjust this value according to actual needs.

[0048] In the embodiment of the present invention, the increased freezing duration is the product of the freezing duration and the preset freezing time adjustment coefficient. The preset freezing time adjustment coefficient takes a value of 1.05; the reduced drying duration is the product of the preset drying time adjustment coefficient and the drying duration, and the preset drying time adjustment coefficient takes a value of 0.98. To ensure that the adjusted freezing duration and drying duration meet the actual requirements, the adjustment range should not be too large, so the adjustment coefficient is correspondingly set to control the adjustment range.

[0049] When the humidity analysis module determines that the single freeze-thaw cycle is unqualified, it determines whether the humidity uniformity of the single freeze-thaw cycle is qualified according to the comparison result between the humidity gradient value of the humidity data and the humidity gradient threshold; If the humidity gradient value is less than or equal to the humidity gradient threshold, it is determined that the humidity uniformity of the single freeze-thaw cycle is qualified; If the humidity gradient value is greater than the humidity gradient threshold, it is determined that the humidity uniformity of the single freeze-thaw cycle is unqualified.

[0050] In the embodiment of the present invention, the humidity gradient threshold takes a value of 10%. The humidity gradient threshold is obtained by taking the average value of the humidity gradient values of several historical qualified humidity uniformities, but the above value is not limited to this, and those skilled in the art can also adjust this value according to actual needs.

[0051] During implementation, the humidity gradient value is the ratio of the sum of the differences between the maximum and minimum humidity values at different positions in the drying chamber or the freezing chamber divided by the average humidity value to the number of positions.

[0052] Specifically, when the humidity analysis module determines that the humidity uniformity of a single freeze-thaw cycle is unqualified, it determines the humidity-unqualified chamber based on the comparison result between the humidity change rate of the humidity data and the preset humidity change rate. If the humidity change rate is less than or equal to the preset humidity change rate, it is determined that the humidity of a single chamber is unqualified. If the humidity change rate is greater than the preset humidity change rate, it is determined that the humidity of both chambers is unqualified.

[0053] In an embodiment of the present invention, the preset humidity change rate is set to 1% / min, but the above value is not limited to this, and those skilled in the art can also adjust this value according to actual needs.

[0054] During implementation, the humidity change rate is the ratio of the change amount of humidity to the time interval.

[0055] In an embodiment of the present invention, the unqualified humidity of a single chamber means that the humidity of one of the freezing chamber or the drying chamber is unqualified, and the unqualified humidity of both chambers means that the humidity of both the freezing chamber and the drying chamber is unqualified.

[0056] Specifically, in the present invention, when the hydrogel structure is unstable, the freezing time or the drying time is adjusted according to the difference between the concentration difference change characterization parameter and the preset concentration difference change characterization parameter, and when a single freeze-thaw cycle is unqualified, the humidity uniformity is judged according to the humidity gradient value, and when it is unqualified, the humidity-unqualified chamber is determined according to the humidity change rate, which improves the preparation accuracy and pertinence, and avoids affecting the performance and quality of the hydrogel due to humidity non-uniformity problems.

[0057] Specifically, when the data adjustment module determines that the humidity of a single chamber is unqualified, it determines to adjust the temperature of the single chamber according to the comparison result between the ratio of the humidity change rate to the preset humidity change rate and the preset ratio. If the ratio is less than or equal to the preset ratio, it is determined to reduce the freezing temperature of the freezing chamber to the corresponding value with a preset freezing temperature adjustment coefficient of 0.95. If the ratio is greater than the preset ratio, it is determined to increase the drying temperature of the drying chamber to the corresponding value with a preset drying temperature adjustment coefficient of 1.07. The ratio is the ratio of the humidity change rate to the preset humidity change rate.

[0058] In an embodiment of the present invention, the preset ratio is set to 0.85, but the above value is not limited to this, and those skilled in the art can also adjust this value according to actual needs.

[0059] In the embodiment of the present invention, the reduced freezing temperature is the product of the freezing temperature and a preset freezing temperature adjustment coefficient, and the value of the preset freezing temperature adjustment coefficient is 0.95; the increased drying temperature is the product of the drying temperature and a preset drying temperature adjustment coefficient, and the value of the preset drying temperature adjustment coefficient is 1.07. To ensure that the adjusted freezing temperature and drying temperature meet the actual requirements, the adjustment range should not be too large. Therefore, the adjustment coefficient is correspondingly set to control the adjustment range.

[0060] Specifically, when the data adjustment module determines that the humidity in both chambers is unqualified, it determines the adjustment of the fan speed according to the comparison result of the relative difference between the humidity change rate and the preset humidity change rate and the preset relative difference. If the relative difference is less than or equal to the preset relative difference, it is determined to increase the fan speed to the corresponding value with a first preset speed adjustment coefficient of 1.12. If the relative difference is greater than the preset relative difference, it is determined to increase the fan speed to the corresponding value with a second preset speed adjustment coefficient of 1.16. The relative difference is the relative difference between the humidity change rate and the preset humidity change rate.

[0061] In the embodiment of the present invention, the value of the preset relative difference is 0.3, but the above value is not limited to this, and those skilled in the art can also adjust this value according to actual needs.

[0062] In the embodiment of the present invention, the increased fan speed is the product of the fan speed and a preset speed adjustment coefficient. The preset speed adjustment coefficient includes a first preset speed adjustment coefficient with a value of 1.12 and a second preset speed adjustment coefficient with a value of 1.16. The fan speed includes a freezing speed and a drying speed. To ensure that the adjusted fan speed meets the actual requirements, the adjustment range should not be too large. Therefore, the adjustment coefficient is correspondingly set to control the adjustment range.

[0063] Specifically, the present invention adjusts the freezing temperature or the drying temperature according to the ratio of the humidity change rate to the preset humidity change rate when the humidity in a single chamber is unqualified, and adjusts the fan speed according to the relative difference between the humidity change rate and the preset humidity change rate when the humidity in both chambers is unqualified, reducing the influence of humidity fluctuations on the performance of the hydrogel and improving the stability and consistency of the hydrogel quality.

[0064] So far, the technical solution of the present invention has been described in combination with the preferred embodiments shown in the drawings. However, it is easy for those skilled in the art to understand that the protection scope of the present invention is obviously not limited to these specific embodiments. Without departing from the principle of the present invention, those skilled in the art can make equivalent changes or substitutions to the relevant technical features, and the technical solutions after these changes or substitutions will fall within the protection scope of the present invention.

[0065] The above are only the preferred embodiments of the present invention and are not intended to limit the present invention. For those skilled in the art, the present invention may have various modifications and variations. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention shall be included within the protection scope of the present invention.

Claims

1. A complete set of production equipment for hydrogel particles, characterized in that, Comprising: An environmental chamber, which includes a freezer and a drying chamber, A detection mechanism, which includes an oxygen detection device for detecting the indoor oxygen concentration and a humidity detection device for detecting the indoor humidity, respectively arranged in the freezer and the drying chamber; A control mechanism, which is arranged in the environmental chamber and includes, A data acquisition module, which is used to obtain the oxygen concentration data and humidity data detected by the detection mechanism; An oxygen analysis module, which is connected to the data acquisition module and is used to determine whether a single freeze-thaw cycle is qualified based on the single-cycle oxygen concentration difference of the oxygen concentration data; A data processing module, which is connected to the oxygen analysis module and is used to determine whether the structure of the hydrogel is stable based on the change characterization parameter of the concentration difference after three freeze-thaw cycles under the condition that a single freeze-thaw cycle is qualified, so as to determine whether to adjust the freezing duration or the drying duration according to the difference between the change characterization parameter of the concentration difference and the preset change characterization parameter of the concentration difference; A humidity analysis module, which is connected to the data processing module and is used to determine whether the humidity uniformity of a single freeze-thaw cycle is qualified based on the humidity gradient value of the humidity data under the condition that a single freeze-thaw cycle is unqualified, so as to determine the environmental chamber with unqualified humidity according to the humidity change rate of the humidity data; A data adjustment module, which is connected to the humidity analysis module and is used to determine whether to adjust the temperature of the freezer or the drying chamber based on the ratio of the humidity change rate to the preset humidity change rate or to determine whether to adjust the fan speed based on the relative difference between the humidity change rate and the preset humidity change rate.

2. The hydrogel particle complete production equipment according to claim 1, characterized in that, The oxygen analysis module determines that a single freeze-thaw cycle is qualified based on the comparison result that the single-cycle oxygen concentration difference of the oxygen concentration data is less than or equal to the preset single-cycle oxygen concentration difference, and determines that the structure of the hydrogel is stable according to the comparison result that the change characterization parameter of the concentration difference is less than or equal to the preset change characterization parameter of the concentration difference.

3. The hydrogel particle complete production equipment according to claim 2, characterized in that, The oxygen analysis module determines that a single freeze-thaw cycle is qualified based on the comparison result that the single-cycle oxygen concentration difference of the oxygen concentration data is less than or equal to the preset single-cycle oxygen concentration difference, and determines that the structure of the hydrogel is unstable according to the comparison result that the change characterization parameter of the concentration difference is greater than the preset change characterization parameter of the concentration difference.

4. The hydrogel particle complete production equipment according to claim 3, characterized in that, When the data processing module determines that the structure of the hydrogel is unstable, the process of adjusting the freezing duration or the drying duration includes: Subtracting the change characterization parameter of the concentration difference from the preset change characterization parameter of the concentration difference; Determining to increase the freezing duration of the freezer with a preset freezing time adjustment coefficient based on the comparison result that the difference is less than or equal to the preset difference; Determining to increase the drying duration of the drying chamber with a preset drying time adjustment coefficient based on the comparison result that the difference is greater than the preset difference.

5. The hydrogel particle complete production equipment according to claim 4, characterized in that, The oxygen analysis module determines that a single freeze-thaw cycle is unqualified based on the comparison result that the single-cycle oxygen concentration difference of the oxygen concentration data is greater than the preset single-cycle oxygen concentration difference, and determines that the humidity uniformity of a single freeze-thaw cycle is unqualified according to the comparison result that the humidity gradient value of the humidity data is greater than the humidity gradient threshold.

6. The hydrogel particle complete production equipment according to claim 5, characterized in that, When the humidity analysis module determines that the humidity uniformity of a single freeze-thaw cycle is unqualified, it determines that the humidity of the freezer or the drying chamber is unqualified based on the comparison result that the humidity change rate of the humidity data is less than or equal to the preset humidity change rate.

7. The hydrogel particle complete production equipment according to claim 6, characterized in that, When the humidity analysis module determines that the humidity uniformity of a single freeze-thaw cycle is unqualified, it determines that the humidity of both the freezer and the drying chamber is unqualified based on the comparison result that the humidity change rate of the humidity data is greater than the preset humidity change rate.

8. The hydrogel particle complete production equipment according to claim 7, characterized in that, When the data adjustment module determines that the humidity of the freezer or the drying chamber is unqualified, the process of adjusting the temperature of the freezer or the drying chamber includes: Dividing the humidity change rate by the preset humidity change rate; Based on the comparison result that the ratio is less than or equal to the preset ratio, determining to decrease the freezing temperature of the freezer by the preset freezing temperature adjustment coefficient; Based on the comparison result that the ratio is greater than the preset ratio, determining to increase the drying temperature of the drying chamber by the preset drying temperature adjustment coefficient.

9. The hydrogel particle complete production equipment according to claim 8, characterized in that, When the data adjustment module determines that the humidity of both the freezer and the drying chamber is unqualified, the process of adjusting the fan speed includes: Calculating the relative difference between the humidity change rate and the preset humidity change rate; Setting a number of adjustment coefficients corresponding to the respective relative differences; Increasing the fan speed based on the several adjustment coefficients; Setting the corresponding relationship between the respective relative differences and the increased fan speed to adjust the fan speed.

10. A complete set of production methods for hydrogel particles, using the complete set of production equipment for hydrogel particles described in any one of claims 1-9, characterized in that, Including: Obtaining the oxygen concentration data and humidity data detected by the detection agency; Determining whether a single freeze-thaw cycle is qualified based on the oxygen concentration difference of a single cycle of the oxygen concentration data; Under the condition that a single freeze-thaw cycle is qualified, determining whether the structure of the hydrogel is stable according to the concentration difference change characterization parameter after three freeze-thaw cycles, and determining to adjust the freezing duration or the drying duration according to the difference between the concentration difference change characterization parameter and the preset concentration difference change characterization parameter; Under the condition that a single freeze-thaw cycle is unqualified, determining whether the humidity uniformity of a single freeze-thaw cycle is qualified according to the humidity gradient value of the humidity data, and determining the environmental chamber with unqualified humidity according to the humidity change rate of the humidity data; Determining to adjust the temperature of the freezer or the drying chamber based on the ratio of the humidity change rate to the preset humidity change rate, or determining to adjust the fan speed based on the relative difference between the humidity change rate and the preset humidity change rate.

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