Reagent card incubation device and reagent card incubation control method thereof

By using multiple independent heating units and temperature detection units in the reagent card incubation device, combined with photoelectric sensors and control modules, the independent temperature control of the reagent card is realized, and the problem of insufficient coordination between multi-region temperature control and timing in the prior art is solved, and the experimental efficiency and detection accuracy are improved.

CN120361958APending Publication Date: 2025-07-25SHANDONG INST OF MEDICAL DEVICES & DRUG PACKAGING INSPECTION
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Patent Information

Application Number
CN202510658987.4
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-05-21
Publication Date
2025-07-25

AI Technical Summary

Technical Problem

The existing reagent card incubation device cannot achieve multi-region independent temperature control and timing coordination, resulting in low experimental efficiency and inaccurate detection results caused by heating timeout or temperature error.

Method used

When multiple independent heating units and temperature detection units are adopted, combined with photoelectric sensors and control modules, the independent temperature control of each slot is realized, and the reagent card is in place is detected through the photoelectric sensor, and the independent countdown is automatically triggered and the heating is stopped to ensure accurate synchronization of temperature and time.

Benefits of technology

Differentiated incubation of multi-slot reagent cards is realized, batch processing efficiency is improved, operation error rate is reduced, and detection results are improved.

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Abstract

The invention relates to the technical field of reagent card incubation, and discloses a temperature-control timing reagent card incubation device, which comprises: a shell provided with a plurality of reagent card placing grooves; the heating module comprises a plurality of heating units arranged in the shell, and each heating unit corresponds to one reagent card placing groove; the temperature detection module comprises a plurality of temperature detection units, and each temperature detection unit is correspondingly arranged in one reagent card placing groove and used for detecting the real-time temperature in the groove; the photoelectric detection module comprises a plurality of photoelectric sensors, and each photoelectric sensor is correspondingly arranged in one reagent card placing groove; when the temperature reaches the incubation temperature and a reagent card is put in, independent countdown of the corresponding slot position is automatically triggered, and heating is automatically stopped when the independent countdown is finished, so that the risk of overheating caused by manual forgetting of taking out is reduced, and accurate synchronization of temperature maintenance and incubation time is realized.
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Description

Technical Field

[0001] The present invention relates to the technical field of reagent card incubation, and more specifically, to a reagent card incubation device and a reagent card incubation control method for the device. Background Art

[0002] In the field of in vitro diagnosis using immunochromatography, the reagent card incubation process has increasingly strict requirements for the accuracy of temperature control and timing management. Traditional incubation equipment mostly adopts an integral constant temperature box structure, and there are the following technical bottlenecks: First, the heating unit usually uses a single-loop PTC heating sheet or a water bath device, which cannot achieve independent temperature control in multiple regions. When processing reagent cards with different temperature requirements, batch operations are required, resulting in low experimental efficiency. Second, incubation timing mostly relies on an external timer or manual recording, and there is no linkage mechanism with the temperature control module. It is difficult to eliminate the timing error caused by the time difference of reagent card placement.

[0003] In the field of in vitro diagnosis, the temperature control accuracy and timing coordination of the reagent card constant temperature incubation device directly affect the reliability of the detection results. In the device disclosed in the prior art such as CN221471880U, although the timing error can be eliminated by positioning photoelectric triggering for independent timing (see claims 1 and paragraph

[0048] of the specification), there are still the following technical defects: First, the heating module uses an integral heating sheet to cover all the card slots (see paragraph

[0048] of the specification "the heating sheet is fixed under the mounting plate" and its attachment Figure 1 )), resulting in multiple reagent cards needing to share the same temperature parameter and being unable to adapt to different incubation requirements (such as performing 37°C and 42°C detections simultaneously). Second, the temperature feedback relies on a single display digital tube (paragraph

[0054] of the specification), lacking a slot-level visual interaction design. Operators need to repeatedly check the correspondence between the sockets and the display unit, which is prone to causing human misjudgment.

[0004] In summary, in the above solutions, when an operator processes multiple detection items simultaneously, there is still a risk of missing or confusing the recording of the sample addition time; with a single heating plate, precise coordinated control of time and temperature cannot be achieved. After the time is up, the operator needs to immediately take out the reagent card in that slot because the heating sheet still needs to heat other card slots, and it is impossible to stop the entire heating plate from heating. If the manual removal is slow or forgotten, overheating will occur, resulting in the loss of biological activity (biological molecules such as antibodies, antigens, or enzymes in the reagent card are sensitive to temperature, and overheating may cause protein denaturation, losing the ability to bind to the target, resulting in false negative or false positive results) or damage to the reagent mechanism (the color development layer or reaction film of some reagents may undergo physical changes due to continuous high temperature, such as drying and cracking, affecting the liquid chromatography process, resulting in abnormal color development or inability to interpret the results).

[0005] In view of the above defects, there is an urgent need for an incubation device that integrates multi-loop independent temperature and time control, slot-level optical signal feedback, and intelligent collaborative triggering, further breaking through bottlenecks such as time and temperature errors and low human-computer interaction efficiency, and realizing the precision and automation requirements in large-scale detection scenarios. Summary of the Invention

[0006] The present invention aims to overcome at least one of the above-mentioned existing technical defects and provides a temperature-controlled and time-measured reagent card incubation device for solving the fundamental problem that when a reagent card is placed, the time and temperature cannot be independently and precisely controlled in a coordinated manner.

[0007] The present invention is solved as follows: The present invention discloses a temperature-controlled and time-measured reagent card incubation device, including: a housing, on which a plurality of reagent card placement slots are provided; a heating module, including a plurality of heating units arranged in the housing, each heating unit corresponding to a reagent card placement slot; a temperature detection module, including a plurality of temperature detection units, each temperature detection unit being correspondingly arranged in a reagent card placement slot for detecting the real-time temperature in the slot; a photoelectric detection module, including a plurality of photoelectric sensors, each photoelectric sensor being correspondingly arranged in a reagent card placement slot for judging the presence state of the reagent card by detecting the change in the intensity of the reflected light; a control module, arranged in the housing and electrically connected to the heating module, the temperature detection module, and the photoelectric detection module respectively, and the control module is configured to: adjust the heating state of the corresponding heating unit according to the feedback signal of the temperature detection unit so that the temperature in the reagent card placement slot reaches the preset incubation temperature; when a certain reagent card placement slot has a preset incubation time, and the temperature reaches the preset incubation temperature, and the photoelectric sensor detects that the reagent card is in place, start the independent countdown of the corresponding slot; at the end of the independent countdown, control the heating unit of the corresponding slot to stop heating.

[0008] Through the heating units and temperature detection units independently configured for each reagent card placement slot, independent closed-loop regulation of the temperature of each slot is realized, avoiding temperature interference between multiple slots and ensuring the uniformity and stability of the incubation temperature. Independent and autonomous temperature-time coordinated control: The presence state of the reagent card is detected by the photoelectric sensor, and when the temperature reaches the incubation temperature and the reagent card is placed, the independent countdown of the corresponding slot is automatically triggered, and the heating is automatically stopped at the end of the independent countdown, reducing the risk of overheating caused by human forgetting to take out, and realizing the precise synchronization of temperature maintenance and incubation time. Multi-task parallel processing: The heating, temperature detection, and timing functions of each slot operate independently, supporting the simultaneous incubation of multiple reagent cards with different time and temperature requirements without mutual influence, significantly improving the batch processing efficiency. Structural compactness and reliability: The heating module, temperature detection module, and control module are integrated inside the housing, reducing the dependence on external devices, lowering the complexity of the device, and being suitable for rapid deployment in laboratories or on-site.

[0009] Further, it further includes: a three-color light is provided in each reagent card placement slot, and the three-color light is electrically connected to the control module and configured to perform the following instructions based on the slot status: Blue: The temperature of this slot has not reached the preset incubation temperature or the incubation time has not been set; Green: The temperature of this slot has reached the preset incubation temperature and the incubation time has been set; Red: When the slot is in the green state and the photoelectric sensor detects that the reagent card is in place, the three-color light switches to red and starts an independent countdown; Green flashing: When the independent countdown ends, the three-color light switches to green flashing to prompt the removal of the reagent card. Through the visual feedback system with three-state color coding, multi-dimensional status synchronization indication is achieved. Without the need to rely on additional instruments, the operator can intuitively judge the slot preparation status (blue), ready status (green), working status (red), and completion status (green flash), significantly reducing the operation error rate, effectively improving the user experience of the operator, and enhancing the human-machine interaction friendliness of the device.

[0010] Further, the three-color light protrudes 1-3 mm from the bottom surface of the reagent card placement slot. The 1-3 mm raised three-color light structure design is adopted. Since the reagent card placement slot is much larger than the size of a general reagent card, while ensuring the stable placement of the reagent card, it effectively solves the problem of the visual blind area caused by the reagent card blocking the three-color light, enhancing the visibility of the status indication.

[0011] Further, the temperature detection unit is a thermistor. Selecting a thermistor as the temperature detection unit has the advantages of high measurement accuracy, low cost, strong anti-electromagnetic interference, and fast response speed while achieving high measurement accuracy, and is particularly suitable for the high-density temperature monitoring requirements in the multi-channel independent temperature control scenario.

[0012] Further, the detection surface of the photoelectric sensor is flush with the bottom plane of the reagent card placement slot, and an infrared reflection detection structure is adopted. Whether the reagent card is in place is judged by detecting the change in the reflection intensity of infrared light on the surface of the reagent card. In technical fields (such as optical sensing, electronic detection, etc.), the infrared reflection detection structure belongs to common knowledge, and is widely used and technically mature especially in fields such as sensor design, automation control, and medical equipment. Utilizing the basic process of infrared light emission → object reflection → signal reception belongs to the classic method of photoelectric detection, which was proposed and popularized in the mid-late 20th century. For example, the reflection / absorption characteristics of infrared light and matter are textbook-level contents in optics and electronics. Through the coplanar installation of the infrared reflection photoelectric sensor, the risk of jamming caused by the traditional mechanical trigger detection mechanism is eliminated.

[0013] Further, it also includes a sound prompt unit disposed inside the housing, and the control module controls the sound prompt unit to emit a prompt sound when the independent countdown ends. An integrated sound and light dual-mode prompt system triggers a buzzer prompt (with adjustable duration) synchronously when the independent countdown ends. Through a multi-sensory collaborative warning mechanism, it ensures that the completion notice can still be effectively received in a noisy laboratory environment or when the operator's line of sight leaves the device, avoiding detection failure caused by over-incubation of reagents.

[0014] Further, the control module is configured to receive a mode switching instruction. When a certain reagent card placement slot switches to the pure timing mode, the control module immediately cuts off the power supply of the corresponding heating unit, and directly starts an independent countdown when the photoelectric sensor detects that the reagent card is in place, ignoring the feedback signal of the temperature detection module. To further expand the application scenarios, this device can also be switched to the pure timing mode through the control module. In this mode, the heating function is forcibly turned off, and the system only triggers an independent countdown according to the in-place state of the reagent card, which is applicable to room temperature incubation experiments without heating (such as some immunochromatographic reagent cards without heating incubation), meeting diverse detection requirements.

[0015] A reagent card incubation control method based on the aforementioned device includes the following steps: S1. Parameter setting: The user sets the incubation temperature and incubation time for a single / multiple reagent card placement slots; S2. Temperature adjustment: The control module starts the heating unit of the corresponding slot according to the incubation temperature in S1; and dynamically adjusts the power of the heating unit based on the real-time feedback signal of the temperature detection unit of the corresponding slot until the temperature in the slot reaches the incubation temperature in S1; S3. Status determination and independent countdown trigger: If the temperature of the corresponding slot does not reach the incubation temperature in S1, or no incubation time is set in S1, the three-color light shows blue, and it is prohibited to put the reagent card; If the temperature of the corresponding slot reaches the preset incubation temperature and the preset incubation time is set, the three-color light switches to green, allowing the reagent card to be put in; When the reagent card is put in and the photoelectric sensor detects it in place, the three-color light turns red and starts an independent countdown for the corresponding slot; S4. Independent countdown termination: When the independent countdown ends, the control module turns off the heating unit of the corresponding slot and switches the three-color light to green flashing to prompt the user to take out the reagent card. Establish a dual verification mechanism of temperature compliance and physical presence. Through the "blue - green - red - green flash" status chain logic, the operation process is forced to be standardized, preventing both insufficient reactions (false negatives) caused by low-temperature loading and energy waste caused by mis-starting without a load, as well as heating timeout caused by slow or forgotten manual removal.

[0016] Further, after removing the reagent card in S4, any of the following processing modes is adopted for the vacant reagent card placement slot: Mode 1: After the photoelectric sensor detects the removal of the reagent card, the three-color lamp automatically turns off; Mode 2: After the photoelectric sensor detects the removal of the reagent card, the control module automatically continues to use the previously set incubation temperature and incubation time, restarts the heating unit to adjust the temperature, and switches the three-color lamp to green after the temperature reaches the standard, allowing a new reagent card to be placed. Provide intelligent post-processing dual-mode selection. Mode 1 realizes energy-saving operation (reduced power consumption) that stops immediately when in use, and Mode 2 supports continuous batch processing through the parameter memory function, which is especially suitable for large-scale detection scenarios such as epidemic screening. The batch switching efficiency is improved, the frequency of manual intervention is reduced, and the incubation efficiency of the reagent card can be greatly improved.

[0017] Further, Mode 2 can be executed in a loop. When and only when the previously set incubation temperature and incubation time have not been manually modified by the user, the control module automatically continues to use the previous parameters to start a new round of incubation process. The automatic continuous batch processing function is realized through loop execution, which can further improve the user experience and incubation efficiency, and ensure the consistency of temperature parameters between multiple batches of detections.

[0018] Compared with the prior art, the beneficial effects of the present invention are: The control module receives the temperature signal and the in-place signal of the photoelectric sensor, that is, when the temperature reaches the standard and it is detected that the reagent card is placed, it automatically triggers an independent countdown for the corresponding slot, and can separately stop the heating of the heating unit of the corresponding reagent card placement slot after the countdown ends; in this way, when the reagent card is placed, it can independently and autonomously achieve precise control of time and temperature coordination. The silicon rubber heating plate is used to achieve precise temperature control in zones, ensuring independent closed-loop temperature regulation for each slot and avoiding temperature interference between multiple slots. Through modular design and independent control mechanism, the device realizes parallel processing of multi-slot differential incubation, improves the batch operation efficiency, solves the problem that the existing equipment cannot independently and autonomously achieve precise control of time and temperature coordination due to overall temperature control, is suitable for laboratory and on-site rapid deployment, and significantly improves the accuracy of detection results and the convenience of operation. Description of the Drawings

[0019] Figure 1 It is a schematic diagram of the overall structure of the present invention.

[0020] Figure 2 It is a schematic diagram of the inner side of the upper shell of the present invention.

[0021] Figure 3 It is a schematic diagram of the surface of the upper shell of the present invention.

[0022] Figure 4This is a schematic diagram of the inner side of the lower housing of the present invention.

[0023] In the figure: 1. Upper housing; 2. Lower housing; 3. Display screen; 4. Photoelectric sensor; 5. Three-color lamp; 6. Three-color lamp board; 7. Silicone rubber heating plate; 8. Thermistor; 9. Switch socket filter; 10. Power module; 11. Temperature and time control circuit board; 12. Reagent card placement slot. Detailed implementation manners

[0024] The attached drawings of the present invention are only for illustrative purposes and should not be construed as a limitation to the present invention. To better illustrate the following embodiments, some components in the drawings will be omitted, enlarged or reduced, which do not represent the dimensions of the actual product; for those skilled in the art, it is understandable that some well-known structures and their descriptions in the drawings may be omitted.

[0025] The present invention relates to a temperature-controlled and time-measured reagent card incubation device, which adopts a modular design and includes the following core components: Housing: It includes an upper housing 1 and a lower housing 2. On the outer surface of the upper housing 1, a plurality of reagent card placement slots 12 are horizontally arranged in an array. The slot size of the reagent card placement slot 12 is larger than that of a general reagent card (the width of a general reagent card is 20 mm and the length is 100 mm). Specifically, the width of the reagent card placement slot 12 is: 40 mm, and the length is 120 mm. With such a setting, it can be adapted to the placement of reagent cards of different sizes, and can effectively increase its application range. In this solution, a plurality of reagent card placement slots 12 are provided on the surface of the housing 1, specifically as Figure 1 shown, which is suitable for the independent detection scenario of a large number of reagent cards.

[0026] Human-computer interaction module: A display screen 3, which is embedded on the surface of the upper housing 1. It is a 7-inch touch screen, fixed by screws, and is electrically connected to the internal controller, and is used for parameter setting and status display.

[0027] Heating module: A silicone rubber heating plate 7, which is installed on the inner side of the upper housing 1. It adopts a multi-loop layout design. The internal heating wire is divided into a plurality of independent heating loops, and each loop is a heating unit. Each heating unit corresponds to a reagent card placement slot 12. Specifically, the heating component can also adopt an independent resistance heating sheet, which is connected to the controller through an independent electrode lead to achieve precise temperature control in different regions.

[0028] Temperature detection module: It includes a temperature detection unit arranged in the reagent card placement slot 12. The temperature detection unit is specifically a thermistor 8. Each reagent card placement slot 12 is embedded with this thermistor 8. Specifically, a Heraeus thermistor is selected: The Heraeus thermistor takes thin-film platinum technology as the core and uses high-purity platinum material to form a nanoscale thin film layer (thickness 0.9 - 1.3 mm) through the ion beam sputtering process.

[0029] Photoelectric detection module: Specifically, it is the photoelectric sensor 4. One photoelectric sensor 4 is embedded at the bottom of each reagent card placement slot 12. Specifically, the MEXICO photoelectric sensor is selected. It uses an infrared light source to detect the in-position state of the reagent card, triggers a signal through the change in the intensity of the reflected light, and has no mechanical protrusion design to avoid interfering with the placement of the reagent card.

[0030] Three-color light board 6: One light board corresponds to each row of reagent card placement slots 12. The number of three-color lights 5 on each light board is the same as the number of slots in a row (the position of the reagent card placement slot 12, simply referred to as the slot) and the positions correspond. The three-color light 5 protrudes 2 mm from the bottom of the slot. The heating state is displayed through the three colors of blue, green, red, and green flash. Blue indicates that the temperature of this slot has not reached the preset incubation temperature or the incubation time has not been set. Green indicates that the temperature of this slot has reached the preset incubation temperature and the incubation time has been set. Red indicates that heating and timing are in progress, that is, incubation is in progress. Green flashing indicates that the temperature has reached the standard and the countdown has ended, that is, incubation is completed. In this solution, the photoelectric detection module is located at one end of the reagent card placement slot 12, and the three-color light 5 is located at the other end of the reagent card placement slot 12. When the reagent card is placed, it first aligns with the end with the photoelectric sensor, triggering the photoelectric detection module; because the size of the reagent card placement slot 12 is larger than that of a general reagent card, the three-color light 5 will not be blocked when the reagent card is placed.

[0031] Control module: Specifically, it is the temperature and time control circuit board 11, which is integrated in the lower housing 2 and built-in with a STM32F4 series controller, supporting the PID temperature algorithm and the high-precision timing function for multiple slots independently. The signal of the thermistor 8 is directly fed back to the controller (STM32F4 series controller), and the controller controls the resistance heating sheet or heating wire of the silicone rubber heating plate 7 of the corresponding slot to stop heating according to the signal. The temperature and time control circuit board 11 is integrated with a memory, and the memory stores preset temperature parameters, incubation time parameters, and mode switching instructions. The controller is connected to the silicone rubber heating plate, temperature detection unit, and photoelectric sensor through electrical connection wires respectively.

[0032] Sound prompt unit: It is a buzzer, connected to the temperature and time control circuit board 11, and triggers a prompt sound when the countdown ends.

[0033] Power supply module 10: Supplies power to each component. The switch socket filter 9 is connected to the power input terminal, and suppresses high-frequency noise through the LC filter circuit to ensure the power supply stability of the system.

[0034] System working principle: Temperature control logic: The user sets the temperature of the target reagent card placement slot 12 (such as 37°C) through the display screen 3. The controller drives the corresponding area of the silicone rubber heating plate 7 to supply power. The thermistor 8 collects the temperature in the slot in real time. The controller dynamically adjusts the heating power through the PID algorithm until the temperature is stable within the range of the set value ±0.2°C. During the heating process, initially, the three-color light 5 is colorless. When heating, the three-color light 5 shows blue. After the incubation time is preset and the temperature reaches the standard, it switches to green.

[0035] Timing trigger and status feedback: When the reagent card is placed in the reagent card placement slot 12, the photoelectric sensor 4 detects the change in the reflected light intensity (the threshold is set to 150% of the background light intensity) and sends an in-place signal to the controller. The controller starts an independent countdown and at the same time switches the three-color light 5 of the corresponding slot to red. After the independent countdown ends, the controller cuts off the power supply of the heating circuit, the three-color light 5 turns green and flashes, and triggers the buzzer to give a prompt.

[0036] Multi-task parallel processing: The system supports independent operation of multiple slots. The user can set parameters batchwise or individually. Each slot automatically starts timing independently through the photoelectric detection module according to the order in which the reagent cards are placed, which can eliminate the errors caused by the operation time difference. It can also be set through the display screen 3 to make the control module turn off the heating function and only enable the timing function to enter the pure timing mode.

[0037] The user can enable the pure timing mode in the following ways: (a) Trigger the mode switching instruction through the operation of the display screen 3; (b) After the control module receives the instruction, it immediately disconnects the power supply of the corresponding silicone rubber heating plate 7 and displays the "TC-OFF" mark on the interface. The three-color light 5 of the corresponding slot directly shows green; (c) After the reagent card is placed, the photoelectric sensor 4 detects the in-place signal, and the independent countdown starts immediately, regardless of the temperature condition. The three-color light 5 shows red and the independent countdown starts; (d) When the independent countdown ends, the three-color light 5 flashes green to give a prompt.

[0038] When the device is in the aforementioned temperature control and timing collaborative mode, the three-color light 5 follows the state chain of blue → green → red → green flash; when switched to the pure timing mode, the logic of the three-color light 5 is adjusted to: green (mode ready) → red (timing) → green flash (completed). In the pure timing mode, the green state of the three-color light 5 only indicates that the mode is ready and has nothing to do with the temperature parameter. The control module forms a visual distinction from the green state in the temperature control mode by reducing the green brightness or increasing the slow breathing light effect (frequency 0.5Hz). The device supports dual working states of temperature control and timing collaborative mode and pure timing mode. Users can freely switch according to the detection requirements. The temperature determination logic and three-color light encoding in the two modes are independent of each other. Through the differential three-color light encoding design, non-confusing indication of multiple mode states is achieved, ensuring that the operator can quickly identify the current working mode.

[0039] Detailed description of the working process of the temperature control and timing collaborative mode: Step 1: Initially: After the device is powered on, the switch socket filter 9 filters out power grid interference, and the power module 10 supplies power to each component. All three-color lights 5 are in the off state, and the display screen 3 starts the operation interface.

[0040] Step 2: Setting and heating of the incubation temperature; the user inputs the temperature of the target reagent card placement slot 12 through the display screen 3 (multiple reagent cards can be set with the same temperature or separately), the controller parses the instruction and supplies power to the corresponding area of the corresponding silicone rubber heating plate 7. The thermistor 8 continuously feeds back the regional temperature data, and the controller adjusts the heating power through the PID algorithm until the temperature is stable. During the heating process, the three-color light 5 shows blue.

[0041] Step 3: Setting of the incubation time: The user inputs the incubation time of each slot in the interface (multiple slots can be set together or independently). Step 2 and Step 3 can be carried out simultaneously, can be carried out separately, and there is no sequential restriction between Step 2 and Step 3.

[0042] Step 4: Placing the reagent card: When the temperature in the reagent card placement slot 12 is heated to the set temperature and there is also a set incubation time at the same time, the color of the corresponding three-color light 5 in the reagent card placement slot 12 becomes green; the sampling reagent card is placed in the slot with the required incubation time and heating temperature. After the photoelectric sensor 4 detects the reagent card, it triggers an independent countdown, and the corresponding three-color light 5 turns red.

[0043] Step 5: End of the independent countdown and reminder: After the independent countdown is completed, the controller stops heating and switches the three-color light 5 to green flashing, and the buzzer sounds 3 times (0.5 seconds each time, with an interval of 0.2 seconds), controlling the heating unit of the corresponding slot to stop heating. After the user takes out the reagent card, the slot enters the standby state.

[0044] Step 6: Re-incubation of the empty reagent card placement slot 12 (two modes are available): Mode 1: After the reagent card is taken out, the photoelectric sensor 4 detects that the light intensity returns to the background value (≤15 lx, lx is the unit of light intensity), and the three-color lamp 5 automatically turns off.

[0045] Mode 2: Directly use the previous parameters. The silicone rubber heating plate 7 preheats the empty slots, and the three-color lamp 5 shows blue; after the temperature reaches the standard, it switches to green, and the user can put the reagent card back in.

[0046] Key technical advantages: The interaction between the three-color lamp 5 and people realizes precise temperature and time control: before the temperature reaches the standard or when the incubation time is not set, the three-color lamp 5 shows blue; when the reagent card placement slot 12 reaches the preset incubation temperature and the incubation time is set at the same time, the three-color lamp 5 shows green; when the reagent card is put in, an independent countdown is triggered, and at the same time the silicone rubber heating plate 7 heats the reagent card, and the three-color lamp 5 shows red; when the independent countdown ends and the heating temperature reaches the standard, the heating stops, and the three-color lamp 5 turns green and continues to flash; Abnormal warning mode: If the temperature exceeds the threshold or the timing is interrupted during the incubation process, the three-color lamp 5 flashes rapidly in red.

[0047] Obviously, the above-mentioned embodiments of the present invention are only examples for clearly explaining the technical solutions of the present invention, rather than limitations on the specific implementation manners of the present invention. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principle of the claims of the present invention shall be included within the protection scope of the claims of the present invention.

Claims

1. A temperature-controlled and timing reagent card incubation device, characterized in that, Comprising: A housing, on which a plurality of reagent card placement slots are provided; A heating module, including a plurality of heating units arranged in the housing, each heating unit corresponding to a reagent card placement slot; A temperature detection module, including a plurality of temperature detection units, each temperature detection unit being correspondingly arranged in a reagent card placement slot for detecting the real-time temperature in the slot; An optoelectronic detection module, including a plurality of optoelectronic sensors, each optoelectronic sensor being correspondingly arranged in a reagent card placement slot for judging the in-position state of the reagent card by detecting the change in the intensity of the reflected light; A control module, arranged in the housing, being electrically connected to the heating module, the temperature detection module and the optoelectronic detection module respectively, and the control module being configured as: Adjusting the heating state of the corresponding heating unit according to the feedback signal of the temperature detection unit so that the temperature in the reagent card placement slot reaches the preset incubation temperature; When a certain reagent card placement slot has a preset incubation time and the temperature reaches the preset incubation temperature, and the optoelectronic sensor detects that the reagent card is in position, starting an independent countdown for the corresponding slot; when the independent countdown ends, controlling the heating unit of the corresponding slot to stop heating.

2. The device according to claim 1, characterized in that, Further comprising: A three-color lamp is arranged in each reagent card placement slot, the three-color lamp being electrically connected to the control module and being configured to perform the following instructions based on the slot state of the reagent card placement slot: Blue: The temperature of this slot has not reached the preset incubation temperature or the incubation time has not been set; Green: The temperature of this slot has reached the preset incubation temperature and the incubation time has been set; Red: When the slot is in the green state and the optoelectronic sensor detects that the reagent card is in position, the three-color lamp switches to red and starts an independent countdown; Green flashing: When the independent countdown ends, the three-color lamp switches to green flashing to prompt to take out the reagent card.

3. The device according to claim 2, characterized in that, The three-color lamp protrudes 1-3 mm from the bottom surface of the reagent card placement slot.

4. The device according to claim 1, characterized in that: The control module is configured to be able to receive a mode switching instruction. When a certain reagent card placement slot switches to the pure timing mode, the control module immediately cuts off the power supply of the corresponding heating unit and directly starts an independent countdown when the optoelectronic sensor detects that the reagent card is in position, ignoring the feedback signal of the temperature detection module.

5. The device according to claim 1, wherein The temperature detection unit is a thermistor.

6. The device according to claim 1, characterized in that, The detection surface of the optoelectronic sensor is flush with the bottom plane of the reagent card placement slot, and an infrared reflection detection structure is adopted to judge whether it is in position by detecting the change in the reflection intensity of infrared light on the surface of the reagent card.

7. The device according to claim 1, characterized in that, Further comprising a sound prompt unit arranged in the housing, and the control module controls the sound prompt unit to emit a prompt sound when the independent countdown ends.

8. A reagent card incubation control method based on the device according to any one of claims 2-7, comprising the following steps: S1. Parameter setting: The user sets the incubation temperature and incubation time for a single / multiple reagent card placement slots; S2. Temperature adjustment: The control module starts the heating unit of the corresponding slot according to the incubation temperature in S1; and dynamically adjusts the power of the heating unit based on the real-time feedback signal of the temperature detection unit of the corresponding slot until the temperature in the slot reaches the incubation temperature in S1; S3. Status determination and independent countdown trigger: If the temperature of the corresponding slot does not reach the incubation temperature in S1, or no incubation time is set in S1, the three-color lamp displays blue and it is prohibited to insert the reagent card. If the temperature of the corresponding slot reaches the incubation temperature in S1 and the incubation time is set, the three-color lamp switches to green and it is allowed to insert the reagent card. When the reagent card is inserted and detected by the photoelectric sensor, the three-color lamp turns red and the independent countdown for the corresponding slot is started. S4. Independent countdown termination: When the independent countdown ends, the control module turns off the heating unit of the corresponding slot and switches the three-color lamp to blink green to prompt the user to remove the reagent card.

9. The method according to claim 8, characterized in that After removing the reagent card in S4, any of the following processing modes is adopted for the empty reagent card placement slot: Mode 1: After the photoelectric sensor detects the removal of the reagent card, the three-color lamp automatically turns off. Mode 2: After the photoelectric sensor detects the removal of the reagent card, the control module automatically uses the previously set incubation temperature and incubation time, restarts the heating unit for temperature adjustment, and switches the three-color lamp to green after the temperature reaches the standard, allowing a new reagent card to be inserted.

10. The method according to claim 9, wherein Mode 2 can be executed cyclically. When and only when the previously set incubation temperature and incubation time have not been manually modified by the user, the control module automatically uses the previous parameters to start a new round of incubation process.

Citation Information

Patent Citations

  • Constant-temperature incubation device for reagent card

    CN221471880U