Assembly line for liquid detection
By designing multiple conveying channels and diversion mechanisms on the assembly line, the problems of difficulty in recycling and congestion of the liquid storage tube are solved, convenient recycling and placement of the liquid storage tube is achieved, and the operation efficiency of the assembly line is improved.
Patent Information
- Application Number
- CN202311765410.0
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2023-12-20
- Publication Date
- 2025-07-25
AI Technical Summary
The liquid storage tubes in the existing liquid detection assembly line are difficult to recover and are prone to congestion, especially the congestion caused by the differences in the detection steps of different types of liquid storage tubes.
A flow line including a frame, a mobile station, multiple conveying channels and a diversion mechanism is designed. A storage position is provided on the mobile station, which moves between multiple conveying channels through the drive mechanism, and the liquid storage tube is diverted to different channels through the diversion mechanism to reduce congestion and realize convenient recycling and placement of the liquid storage tube.
It realizes convenient recycling and placement of liquid storage tubes, reduces congestion between different types of liquid storage tubes, and improves the efficiency and operational convenience of the assembly line.
Smart Images

Figure CN120369974A_ABST
Abstract
Description
Technical Field
[0001] The present invention belongs to the technical field of detection equipment, and more specifically, relates to an assembly line for liquid detection and a nucleic acid detection device. Background Art
[0002] In modern medical detection, it is often necessary to load a liquid to be detected (such as saliva, blood sputum, blood, cerebrospinal fluid, pleural effusion, ascites, body fluid, pathological section) into a liquid storage tube (such as a test tube or a sampling tube) and then perform detection (such as nucleic acid detection). In the detection process, usually multiple liquid storage tubes are sequentially placed on an assembly line for transportation for subsequent detection. Generally, there is only one route for the assembly line. The process of placing the liquid storage tube on the assembly line is usually: placing the liquid storage tube at one end of the assembly line, and then the user retrieves it from the other end of the assembly line, which is very troublesome. The detection steps of different types of liquid storage tubes are different. If different types of liquid storage tubes all follow the same route, it is easy to cause congestion. Summary of the Invention
[0003] The purpose of the present invention is to provide an assembly line for liquid detection to solve the technical problems of difficult retrieval of liquid storage tubes and easy congestion existing in the prior art.
[0004] To achieve the above object, the technical solution adopted by the present invention is: providing an assembly line for liquid detection, including: a frame, a moving platform, a first conveying channel arranged on the frame and used for conveying the moving platform, a second conveying channel arranged on the frame and used for conveying the moving platform, a third conveying channel arranged on the frame and used for conveying the moving platform, a diversion mechanism arranged on the frame, and a driving mechanism; a storage position for carrying a liquid storage tube is arranged on the moving platform; the driving mechanism can drive the moving platform to move along the first conveying channel, the second conveying channel, and the third conveying channel; the output end of the first conveying channel is respectively communicated with the input end of the second conveying channel and the input end of the third conveying channel; the diversion mechanism can divert the moving platform in the first conveying channel into the second conveying channel or the third conveying channel; the output end of the second conveying channel is communicated with the input end of the first conveying channel, and the output end of the third conveying channel is communicated with the input end of the first conveying channel.
[0005] Further, it further includes: a photographing mechanism arranged on the frame and used for photographing the liquid storage tube on the moving platform; when the moving platform moves to the first position in the first conveying channel, the photographing mechanism can photograph the liquid storage tube on the moving platform.
[0006] Furthermore, it also includes: a rotating table arranged on the mobile table and a rotating mechanism for driving the rotating table to rotate; the storage position is arranged on the rotating table; when the mobile table moves to the first position, the rotating mechanism can drive the rotating table to rotate.
[0007] Furthermore, the rotating shaft of the rotating table is arranged vertically.
[0008] Furthermore, the rotating mechanism includes: a first tooth portion arranged on the rotating platform, a spur rack extending in a straight direction, and a first driver arranged on the frame and used to drive the spur rack to move along the extension direction of the spur rack; the first tooth portion is arranged around the outside of the rotating shaft of the rotating platform; when the moving platform moves to the first position, the spur rack can be separated from or engaged with the first tooth portion.
[0009] Furthermore, the first driver is a predetermined electric telescopic rod.
[0010] Furthermore, the spur rack is arranged perpendicular to an extension direction of the first conveying channel.
[0011] Furthermore, it also includes: a first electric telescopic rod, a stopper, and a second driver; the second driver is arranged on the frame; the first electric telescopic rod has a first telescopic portion that is telescopic along the first conveying channel and is located outside the moving path of the mobile platform; the stopper is arranged on the first electric telescopic rod, and the second driver can drive the first electric telescopic rod to rotate around the axis of the first electric telescopic rod; when the first electric telescopic rod is rotated to a first angle, the stopper is located on the moving path of the mobile platform to intercept the mobile platform at the first position; when the first electric telescopic rod is rotated to a second angle, the stopper avoids the moving path of the mobile platform.
[0012] Furthermore, the diversion mechanism includes: an intersection space and a first pusher arranged on the frame and capable of placing the movable platform; the output end of the first conveying channel is connected to the intersection space, and the input end of the second conveying channel and the input end of the third conveying channel are respectively connected to the intersection space; the first pusher can push the movable platform in the intersection space into the second conveying channel or the third conveying channel.
[0013] Further, the portion of the first conveying channel connected to the intersection space extends along the first horizontal straight line extension direction, the portion of the second conveying channel connected to the intersection space extends along the second horizontal straight line extension direction; the portion of the third conveying channel connected to the intersection space extends along the second horizontal straight line extension direction;
[0014] The first pusher includes: a second electric telescopic rod and a first moving component arranged on the frame; the second electric telescopic rod has a second telescopic part that can telescopically move in the first horizontal linear extension direction; the first moving component can move the second electric telescopic rod in the second horizontal linear extension direction.
[0015] Further, the first moving component includes: a first slide rail arranged on the frame, a first lead screw rotatably arranged on the frame and parallel to the first slide rail, a first motor arranged on the frame and used to drive the first lead screw to rotate, and a first slider slidably arranged on the first slide rail; the second electric telescopic rod is arranged on the first slider; the first slide rail extends in the second horizontal linear extension direction.
[0016] Further, the driving mechanism includes: a first driving component arranged on the frame and used to drive the moving platform to move along the first conveying channel, a second driving component arranged on the frame and used to drive the moving platform to move along the second conveying channel, and a third driving component arranged on the frame and used to drive the moving platform to move along the third conveying channel.
[0017] Further, the moving platform has a second tooth part;
[0018] The first driving component includes: a first endless rack; the first endless rack has a first toothed belt parallel to the first conveying channel; when the moving platform is located in the first conveying channel, the second tooth part meshes with the first toothed belt;
[0019] The second driving component includes: a second endless rack; the second endless rack has a second toothed belt parallel to the second conveying channel; when the moving platform is located in the second conveying channel, the second tooth part meshes with the second toothed belt;
[0020] The third driving component includes: a third endless rack; the third endless rack has a third toothed belt parallel to the third conveying channel; when the moving platform is located in the third conveying channel, the second tooth part meshes with the third toothed belt.
[0021] Further, it further includes: a first guide rail and a second guide rail arranged in parallel at intervals; the first guide rail and the second guide rail are respectively arranged on the frame; the first conveying channel is formed between the first guide rail and the second guide rail; the outer surface of the first guide rail has a first rib extending along the first guide rail, and the outer surface of the second guide rail has a second rib extending along the second guide rail; the first end of the moving platform has a first groove, and the second end of the moving platform has a second groove; the first rib can be clamped in the first groove, and the second rib can be clamped in the second groove.
[0022] Further, it further includes: a third guide rail and a fourth guide rail which are arranged in parallel at intervals; the third guide rail and the fourth guide rail are respectively arranged on the frame body; the second conveying channel is formed between the third guide rail and the fourth guide rail; a third rib extending along the third guide rail is provided on the outer surface of the third guide rail, and a fourth rib extending along the fourth guide rail is provided on the outer surface of the fourth guide rail; the third rib can be clamped in the first groove, and the fourth rib can be clamped in the second groove.
[0023] Further, it further includes: a fifth guide rail and a sixth guide rail which are arranged in parallel at intervals; the fifth guide rail and the sixth guide rail are respectively arranged on the frame body; the third conveying channel is formed between the fifth guide rail and the sixth guide rail; a fifth rib extending along the fifth guide rail is provided on the outer surface of the fifth guide rail, and a sixth rib extending along the sixth guide rail is provided on the outer surface of the sixth guide rail; the fifth rib can be clamped in the first groove, and the sixth rib can be clamped in the second groove.
[0024] Further, it further includes: a feeding mechanism for storing the liquid storage tube and a first transfer device which is arranged on the frame body and is used for transferring the liquid storage tube on the feeding mechanism into the first conveying channel.
[0025] Further, the first transfer device includes: a first gripper for clamping the liquid storage tube and a first transfer mechanism for driving the first gripper to move in the XYZ directions.
[0026] Further, the feeding mechanism includes: a plurality of sliding members, a sample tray for placing the liquid storage tube, a plurality of sample racks which are arranged on the sliding members and are used for placing the sample tray, a seat body arranged on the frame body, and a driving unit arranged on the frame body; the seat body has a sliding channel for the plurality of sliding members to slide in a cycle, and the driving unit can drive the plurality of sliding members to slide along the sliding channel; the plurality of sliding members correspond to the plurality of sample racks one by one.
[0027] Further, the sliding channel is in a circular closed shape.
[0028] Further, the driving unit includes: a chain arranged on the frame body and capable of moving in a cycle and a third driver for driving the chain to move in a cycle; the plurality of sliding members are sequentially and fixedly arranged on the chain at intervals.
[0029] Further, the third driver includes: a second motor and a gear; the gear is in transmission connection with the output shaft of the second motor; the gear is engaged with the chain.
[0030] Further, the number of the gears is multiple, and the chain is sleeved and meshed on the multiple gears; an output shaft of the second motor is in transmission connection with one of the gears.
[0031] Further, the number of the gears is four; the trajectory of the chain is in a shape of a rounded rectangle, and the four gears are respectively meshed with four corners of the chain.
[0032] Further, the sample rack has a placing cavity with the bottom surface facing upward for placing the sample tray; when the sample rack moves with the sliding member, the bottom surface of the placing cavity remains facing upward.
[0033] Further, an opening for the sample tray to slide out is formed on a side wall of the placing cavity.
[0034] Further, a duct is formed in a bottom wall of the placing cavity.
[0035] Further, it further includes: a clamping mechanism arranged on the frame body for clamping the liquid storage tube at the storage position, a clamping and opening device for clamping the cover body on the liquid storage tube in the storage position and capable of rotating, and a second transfer mechanism arranged on the frame body for moving the clamping and opening device; when the moving table moves to a second position in the second conveying channel, the clamping mechanism can clamp the liquid storage tube at the storage position.
[0036] Further, the clamping mechanism includes: a first clamping portion, a second clamping portion, and a fourth driver arranged on the frame body for driving the first clamping portion and the second clamping portion to approach and clamp the liquid storage tube at the storage position synchronously.
[0037] Further, the fourth driver includes: a second slide rail arranged on the frame body, a third slide rail arranged on the frame body and parallel to the second slide rail, a second lead screw rotatably arranged on the frame body and parallel to the second slide rail, a third motor arranged on the frame body for driving the second lead screw to rotate, a second slider slidably arranged on the second slide rail, and a third slider slidably arranged on the third slide rail; the first clamping portion is arranged on the second slider, and the second clamping portion is arranged on the third slider; the second lead screw includes: a first screw rod and a second screw rod; the first screw rod and the second screw rod are coaxially arranged, and the thread spiral directions of the first screw rod and the second screw rod are opposite; the second slider is in threaded connection with the first screw rod, and the third slider is in threaded connection with the second screw rod.
[0038] Further, the first clamping portion has a first clamping groove, and the second clamping portion has a second clamping groove; when the first clamping portion and the second clamping portion approach each other, the liquid storage tube on the storage position can be clamped between the inner walls of the first clamping groove and the second clamping groove.
[0039] Further, the clamping and opening device is: a rotating electric claw.
[0040] Further, it further includes: a centrifuge; the second transfer mechanism can transfer the liquid storage tube into the centrifuge.
[0041] Further, a waiting tray for placing the liquid storage tube is provided at the top of the centrifuge housing; the second transfer mechanism can transfer the liquid storage tube to the waiting tray.
[0042] Further, it further includes: a cover storage area provided on the frame for placing the cover.
[0043] Further, it further includes: a pipette for sucking the liquid in the liquid storage tube at the storage position; the second transfer mechanism can drive the pipette to move in the XYZ directions.
[0044] Further, it further includes: a nucleic acid extraction and detection unit, a carrier table provided on the frame, a storage container detachably provided on the carrier table for temporarily storing liquid, and a third transfer mechanism for transferring the storage container into the nucleic acid extraction and detection unit for nucleic acid detection; the pipette can transfer the liquid in the liquid storage tube to the storage container through the second transfer mechanism.
[0045] Further, the storage container has a protective cover; the clamping and opening device can remove and install the protective cover.
[0046] Further, the carrier table can approach or move away from the nucleic acid extraction and detection unit through a second moving component.
[0047] Further, it further includes: a stacking table for stacking the storage containers and a lifting mechanism for driving the stacking table to move up and down; the third transfer mechanism can transfer the objects on the stacking table.
[0048] Further, the nucleic acid extraction and detection unit includes:
[0049] a bracket provided on the frame;
[0050] an amplification device provided on the bracket for adjusting the temperature;
[0051] An extraction device is installed on the amplification device. The extraction device includes a test tube mounting assembly, a first driving member, and a magnetic attracting member. The test tube mounting assembly has a first mounting hole, and the magnetic attracting member is disposed on the hole wall of the first mounting hole. The first driving member is installed on the bracket and is used to drive the test tube mounting assembly to rotate, so as to drive the magnetic attracting member to rotate around the outer peripheral side of the test tube located in the test tube mounting assembly and perform nucleic acid extraction. The third transfer mechanism can transfer the storage container into the first mounting hole.
[0052] A fluorescence detection device is installed on the bracket and is used to perform fluorescence detection on the test tube; and
[0053] A driving device is installed on the bracket, and the output end of the driving device is connected to the amplification device and is used to drive the amplification device and the extraction device to rotate relative to the fluorescence detection device.
[0054] The beneficial effects of the pipeline for liquid detection provided by the present invention are as follows: Compared with the prior art, in the pipeline for liquid detection provided by the present invention, the moving table can be conveyed along the first conveying channel on the frame body, the moving table can be conveyed along the second conveying channel on the frame body, and the moving table can be conveyed along the third conveying channel on the frame body; the driving mechanism can drive the moving table in the first conveying channel to move along the first conveying channel, the driving mechanism can drive the moving table in the second conveying channel to move along the second conveying channel, and the driving mechanism can drive the moving table in the third conveying channel to move along the third conveying channel; a storage position is arranged on the moving table, and the liquid storage tube can be stored in the storage position and move along with the moving table; the output end of the first conveying channel is communicated with the input end of the second conveying channel, and the output end of the first conveying channel is communicated with the input end of the third conveying channel; the shunt mechanism can shunt the moving table conveyed by the first conveying channel to the second conveying channel or the third conveying channel, and the user can shunt different liquid storage tubes to the second conveying channel or the third conveying channel through the shunt mechanism according to actual needs, reducing the congestion between different liquid storage tubes; since the output end of the second conveying channel is communicated with the input end of the first conveying channel, and the output end of the third conveying channel is communicated with the input end of the first conveying channel, assuming that the moving table starts from the input end of the first conveying channel, after the user places the liquid storage tube on the moving table, the moving table can return to the input end of the first conveying channel after passing through the first conveying channel and the second conveying channel, that is, the user can place or recycle the liquid storage tube at the input end of the first conveying channel, and it is very convenient to recycle the liquid storage tube; or the user can return to the input end of the first conveying channel after the moving table passes through the first conveying channel and the third conveying channel, that is, the user can place or recycle the liquid storage tube on the moving table from the same position at the input end of the first conveying channel, and it is very convenient to recycle the liquid storage tube. BRIEF DESCRIPTION OF THE DRAWINGS
[0055] In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the following will briefly introduce the drawings required for use in the description of the embodiments or the prior art. Obviously, the drawings in the following description are only some embodiments of the present invention. For those of ordinary skill in the art, without creative efforts, other drawings can also be obtained based on these drawings.
[0056] Figure 1 Stereoscopic schematic diagram of the assembly line for liquid detection provided by the embodiment of the present invention;
[0057] Figure 2 Schematic diagram of the installation of the sample rack provided by the embodiment of the present invention;
[0058] Figure 3 Schematic diagram of the cooperation between the first clamping mechanism and the first transfer mechanism provided by the embodiment of the present invention;
[0059] Figure 4 Schematic diagram of the movement of the sample rack provided by the embodiment of the present invention;
[0060] Figure 5 For Figure 4 Magnified schematic diagram at position A in
[0061] Figure 6 Schematic diagram of the distribution of the first conveying channel, the second conveying channel, and the third conveying channel provided by the embodiment of the present invention;
[0062] Figure 7 For Figure 5 Magnified schematic diagram at position B in
[0063] Figure 8 For Figure 5 Magnified schematic diagram at position C in
[0064] Figure 9 For Figure 5 Magnified schematic diagram at position D in
[0065] Figure 10 Stereoscopic schematic diagram of the carrier provided by the embodiment of the present invention;
[0066] Figure 11 Stereoscopic schematic diagram of the first pusher provided by the embodiment of the present invention;
[0067] Figure 12 Stereoscopic assembly schematic diagram of the photographing mechanism provided by the embodiment of the present invention;
[0068] Figure 13 Assembly schematic diagram of the moving platform and the rotating platform provided by the embodiment of the present invention;
[0069] Figure 14 Schematic diagram of the three-dimensional cooperation of the first clamping part and the second clamping part provided by the embodiment of the present invention;
[0070] Figure 15 Schematic diagram of the lifting of the stacking table provided by the embodiment of the present invention;
[0071] Figure 16 Schematic three-dimensional diagram of the nucleic acid detection mechanism provided by the embodiment of the present invention;
[0072] Figure 17 Exploded view of the nucleic acid detection mechanism provided by the embodiment of the present invention;
[0073] Figure 18 Exploded three-dimensional diagram of the test tube installation assembly provided by the embodiment of the present invention;
[0074] Figure 19 Schematic diagram of the magnetic part assembly provided by the embodiment of the present invention.
[0075] Among them, the reference numerals in the figure are as follows:
[0076] 1 - Frame; 21 - Mobile stage; 211 - Second tooth part; 212 - First groove; 213 - Second groove; 22 - Rotating stage; 311 - First conveying channel; 312 - Second conveying channel; 3121 - Placing end; 313 - Third conveying channel; 3131 - Recycling end; 32 - Diverting mechanism; 321 - Converging space; 322 - First pusher; 3221 - Second electric telescopic rod; 32211 - Second telescopic part; 323 - First slide rail; 324 - First lead screw; 325 - First motor; 326 - First slider; 331 - First circulating rack; 3311 - First toothed belt; 332 - Second toothed belt; 333 - Third toothed belt; 341 - First guide rail; 3411 - First rib; 342 - Second guide rail; 3421 - Second rib; 35 - Clamping and opening device; 361 - First clamping part; 362 - Second clamping part; 3631 - Second slide rail; 3632 - Third slide rail; 364 - Second lead screw; 3641 - First screw; 3642 - Second screw; 365 - Third motor; 366 - Second slider; 3661 - First sliding part; 3662 - First connecting part; 367 - Third slider; 3671 - Second sliding part; 3672 - Second connecting part; 371 - Pipettor; 371 - Pipettor; 372 - Photographing mechanism; 373 - First tooth part; 374 - Straight rack; 375 - First driver; 376 - First electric telescopic rod; 3761 - First telescopic part; 377 - Stopping part; 378 - Straight rack; 381 - Centrifuge; 3811 - Waiting tray; 382 - Cover storage area; 383 - Loading platform; 3831 - Loading lead screw; 3832 - Loading motor; 3833 - Loading slide rail; 384 - Storage container; 385 - Protective cover; 386 - Stacking platform; 3861 - Lifting lead screw; 3862 - Lifting motor; 3863 - Lifting slide rail; 39 - Second transfer mechanism; 41 - Sliding part; 42 - Sample rack; 421 - Placing cavity; 422 - Opening; 423 - Channel; 43 - Sample tray; 44 - Base; 441 - First track; 442 - Second track; 45 - Sliding channel; 461 - Chain; 462 - Second motor; 463 - Gear; 47 - First gripper; 48 - First transfer mechanism; 5 - Nucleic acid extraction and detection unit; 51 - Bracket; 52 - Amplification device; 53 - Extraction device; 531 - Test tube installation assembly; 5311 - First installation hole; 532 - First driving part; 533 - Magnetic part; 54 - Fluorescence detection device; 55 - Driving device; 56 - Third transfer mechanism; 6 - Liquid storage tube; 61 - Cover body. Detailed implementation manners
[0077] In order to make the technical problems, technical solutions and beneficial effects to be solved by the present invention more clearly understood, the present invention will be further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only used to explain the present invention and are not used to limit the present invention.
[0078] It should be noted that when an element is referred to as being "fixed to" or "disposed on" another element, it can be directly on the other element or indirectly on the other element. When an element is referred to as being "connected to" another element, it can be directly connected to the other element or indirectly connected to the other element.
[0079] It should be noted that in the description of the embodiments of the present application, unless otherwise specified, " / " means "or", for example, A / B can mean A or B; "and / or" herein is only a description of the association relationship of associated objects, indicating that there can be three relationships, for example, A and / or B can mean: A exists alone, A and B exist simultaneously, and B exists alone. Among them, A and B can be singular or plural respectively.
[0080] It should be understood that the orientation or positional relationship indicated by the terms "length", "width", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", etc. is based on the orientation or positional relationship shown in the drawings, and is only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of the present invention.
[0081] In addition, the terms "first" and "second" are only used for descriptive purposes and cannot be understood as indicating or implying relative importance or implicitly indicating the quantity of the indicated technical features. Thus, the features defined with "first" and "second" may explicitly or implicitly include one or more of such features. In the description of the present invention, "a plurality of" means two or more, unless otherwise specifically defined.
[0082] Please refer to Figures 1 to 20. Now, the pipeline for liquid detection provided by the present invention will be described. The pipeline for liquid detection includes: a frame 1, a moving platform 21, a first conveying channel 311 provided on the frame 1 and used for conveying the moving platform 21, a second conveying channel 312 provided on the frame 1 and used for conveying the moving platform 21, a third conveying channel 313 provided on the frame 1 and used for conveying the moving platform 21, a diversion mechanism 32 provided on the frame 1, and a driving mechanism; a storage position for carrying the liquid storage tube 6 is provided on the moving platform 21; the driving mechanism can drive the moving platform 21 to move along the first conveying channel 311, the second conveying channel 312, and the third conveying channel 313; the output end of the first conveying channel 311 is respectively communicated with the input end of the second conveying channel 312 and the input end of the third conveying channel 313; the diversion mechanism 32 can divert the moving platform 21 in the first conveying channel 311 into the second conveying channel 312 or the third conveying channel 313; the output end of the second conveying channel 312 is communicated with the input end of the first conveying channel 311, and the output end of the third conveying channel 313 is communicated with the input end of the first conveying channel 311.
[0083] In this way, the mobile station 21 can be conveyed along the first conveying channel 311 on the frame 1, the mobile station 21 can be conveyed along the second conveying channel 312 on the frame 1, and the mobile station 21 can be conveyed along the third conveying channel 313 on the frame 1; the driving mechanism can drive the mobile station 21 in the first conveying channel 311 to move along the first conveying channel 311, the driving mechanism can drive the mobile station 21 in the second conveying channel 312 to move along the second conveying channel 312, and the driving mechanism can drive the mobile station 21 in the third conveying channel 313 to move along the third conveying channel 313; a storage position is arranged on the mobile station 21, and the liquid storage pipe 6 can be stored in the storage position and move with the mobile station 21; the output end of the first conveying channel 311 is communicated with the input end of the second conveying channel 312, and the output end of the first conveying channel 311 is communicated with the input end of the third conveying channel 313; the shunting mechanism 32 can shunt the mobile station 21 conveyed from the first conveying channel 311 to the second conveying channel 312 or the third conveying channel 313, and the user can shunt different liquid storage pipes 6 into the second conveying channel 312 or the third conveying channel 313 through the shunting mechanism 32 according to actual needs, reducing the congestion between different liquid storage pipes 6; since the output end of the second conveying channel 312 is communicated with the input end of the first conveying channel 311, and the output end of the third conveying channel 313 is communicated with the input end of the first conveying channel 311, assuming that the mobile station 21 starts from the input end of the first conveying channel 311, after the user places the liquid storage pipe 6 on the mobile station 21, the mobile station 21 can return to the input end of the first conveying channel 311 after passing through the first conveying channel 311 and the second conveying channel 312, that is to say, the user can place the liquid storage pipe 6 or recycle the liquid storage pipe 6 at the input end of the first conveying channel 311, and it is very convenient to recycle the liquid storage pipe 6; or the user can also return to the input end of the first conveying channel 311 after the mobile station 21 passes through the first conveying channel 311 and the third conveying channel 313, that is to say, the user can place or recycle the liquid storage pipe 6 on the mobile station 21 from the same position at the input end of the first conveying channel 311, and it is very convenient to recycle the liquid storage pipe 6.
[0084] In one embodiment, the input end of the second conveying channel 312 is: the placing end 3121; the liquid storage pipe 6 is placed at the placing end 3121 to achieve feeding.
[0085] In one embodiment, the output end of the third conveying channel 313 is: the recycling end 3131; the liquid storage pipe 6 moves to the recycling end 3131 to achieve discharging.
[0086] In one embodiment, the placing end 3121 and the recycling end 3131 are respectively conveyer belts moving towards each other.
[0087] In one embodiment, the storage position is directly (or indirectly) set on the mobile station 21 and can be any one of a concave cavity, a receiving cavity or a space capable of storing the liquid storage tube 6. In one embodiment, the storage position is a cylindrical concave cavity with an opening 422 facing upward, and the bottom of the liquid storage tube 6 is inserted into the cylindrical concave cavity.
[0088] In one embodiment, the liquid storage tube 6 is a test tube, a sampling tube (such as a sampling tube for nucleic acid detection), a blood collection tube, etc.
[0089] In one embodiment, the first delivery channel 311 can be any one of a groove, a channel 423, and a space on the frame 1.
[0090] In one embodiment, the second delivery channel 312 can be any one of a groove, a channel 423, and a space on the frame 1.
[0091] In one embodiment, the third delivery channel 313 can be any one of a groove, a channel 423, and a space on the frame 1.
[0092] In one embodiment, the frame 1 is an aluminum frame or a steel frame. In one embodiment, the frame 1 is formed by splicing a plurality of sub - frames.
[0093] Further, please refer to Figures 1 to 2 0. As a specific implementation manner of the pipeline for liquid detection provided by the present invention, it further includes: a photographing mechanism 372 disposed on the frame 1 and used for photographing the liquid storage tube 6 on the mobile station 21; when the mobile station 21 moves to the first position in the first delivery channel 311, the photographing mechanism 372 can photograph the liquid storage tube 6 on the mobile station 21. Thus, when the mobile station 21 moves to the first position in the first delivery channel 311, the photographing mechanism 372 can photograph the liquid storage tube 6 on the mobile station 21 for the user to identify; the shunt mechanism 32 can shunt the mobile station 21 conveyed by the first delivery channel 311 to the second delivery channel 312 or the third delivery channel 313, and the user can shunt different liquid storage tubes 6 to the second delivery channel 312 or the third delivery channel 313 through the shunt mechanism 32 according to the liquid storage tube 6 photographed by the photographing mechanism 372.
[0094] In one embodiment, the way for the photographing mechanism 372 to photograph the liquid storage tube 6 for identification can be: identifying by photographing the label on the liquid storage tube 6 through the photographing mechanism 372. In one embodiment, the way for the photographing mechanism 372 to photograph the liquid storage tube 6 for identification can be: computer identification or manual identification according to the photo obtained by the photographing mechanism 372. In one embodiment, the label can be a bar code or a two - dimensional code. In one embodiment, the photographing mechanism 372 is a camera or a barcode scanner.
[0095] Further, please refer to Figures 1 to 20. As a specific embodiment of the pipeline for liquid detection provided by the present invention, it further includes: a rotating table 22 rotatably arranged on the moving table 21 and a rotating mechanism for driving the rotating table 22 to rotate; a storage position is arranged on the rotating table 22; when the moving table 21 moves to the first position, the rotating mechanism can drive the rotating table 22 to rotate. In this way, there is a storage position on the rotating table 22 for placing the liquid storage tube 6, and the liquid storage tube 6 can be placed on the storage position; the moving table 21 can move along the conveying channel to the first position. When it moves to the first position, the photographing mechanism 372 can photograph the liquid storage tube 6 located on the storage position, and the rotating mechanism can drive the rotating table 22 to rotate. As the rotating table 22 rotates, the photographing mechanism 372 can photograph the liquid storage tube 6 at different angles on the storage position, reducing the risk that the liquid storage tube 6 cannot be photographed by the photographing mechanism 372 due to the incorrect orientation of the label on the liquid storage tube 6, and eliminating the need for manual adjustment of the orientation of the liquid storage tube 6.
[0096] In another possible embodiment, the rotating mechanism is a motor arranged on the moving table 21, and the output shaft of the motor drives the rotating table 22 to rotate.
[0097] In one embodiment, the top of the moving table 21 has a jack, and the bottom of the rotating table 22 is inserted into the jack and can rotate relative to the moving table 21.
[0098] Further, please refer to Figures 1 to 2 0. As a specific embodiment of the pipeline for liquid detection provided by the present invention, the rotating shaft of the rotating table 22 is arranged vertically (vertically: perpendicular to the horizontal plane). In this way, the rotating table 22 can rotate around the vertical rotating shaft.
[0099] Further, please refer to Figures 1 to 2 0. As a specific embodiment of the pipeline for liquid detection provided by the present invention, the rotating mechanism includes: a first tooth portion 373 arranged on the rotating table 22, a straight rack 374 extending in a straight line direction, and a first driver 375 arranged on the frame 1 and used to drive the straight rack 374 to move along the extending direction of the straight rack 374; the first tooth portion 373 is arranged around the outside of the rotating shaft of the rotating table 22; when the moving table 21 moves to the first position, the straight rack 374 can be separated from or engaged with the first tooth portion 373. In this way, when the moving table 21 moves to the first position, the first driver 375 can drive the straight rack 374 to telescopically move along the extending direction of the straight rack 374. When the straight rack 374 is engaged with the first tooth portion 373, the movement of the straight rack 374 can drive the rotating table 22 to rotate; when the straight rack 374 is separated from the first tooth portion 373, the driving of the rotating table 22 can be stopped, and the straight rack 374 is prevented from hindering the movement of the rotating table 22 along with the moving table 21.
[0100] Further, please refer to Figures 1 to 20. As a specific embodiment of the pipeline for liquid detection provided by the present invention, the first driver 375 is a predetermined electric telescopic rod.
[0101] Further, please refer to Figures 1 to 2 0. As a specific embodiment of the pipeline for liquid detection provided by the present invention, the straight rack 374 is arranged perpendicular to the extending direction of the first conveying channel 311.
[0102] Further, please refer to Figures 1 to 2 0. As a specific embodiment of the pipeline for liquid detection provided by the present invention, it further includes: a first electric telescopic rod 376, a stop portion 377, and a second driver 378; the second driver 378 is arranged on the frame 1; the first electric telescopic rod 376 has a first telescopic portion 3761 that extends along the first conveying channel 311 and is located outside the moving path of the moving platform 21; the stop portion 377 is arranged on the first electric telescopic rod 376, and the second driver 378 can drive the first electric telescopic rod 376 to rotate around the axis of the first electric telescopic rod 376; when the first electric telescopic rod 376 rotates to the first angle, the stop portion 377 is located on the moving path of the moving platform 21 to intercept the moving platform 21 at the first position; when the first electric telescopic rod 376 rotates to the second angle, the stop portion 377 avoids the moving path of the moving platform 21. Thus, when the first electric telescopic rod 376 rotates to the second angle, the moving platform 21 can be blocked by the stop portion 377; when the first electric telescopic rod 376 rotates to the first angle, the stop portion 377 can avoid the moving platform 21. In addition, the stop portion 377 can also play a role in pushing the moving platform 21 to move to the first position.
[0103] Further, please refer to Figures 1 to 2 0. As a specific embodiment of the pipeline for liquid detection provided by the present invention, the shunt mechanism 32 includes: a converging space 321 and a first pusher 322; the converging space 321 is arranged on the frame 1, and the converging space 321 can place the moving platform 21; the output end of the first conveying channel 311 is communicated with the converging space 321, and the input ends of the second conveying channel 312 and the third conveying channel 313 are respectively communicated with the converging space 321; the first pusher 322 can push the moving platform 21 in the converging space 321 into the second conveying channel 312 or the third conveying channel 313. Thus, when the moving platform 21 moves to the converging space 321 through the first conveying channel 311, the first pusher 322 can push the moving platform 21 in the converging space 321 into the second conveying channel 312 or the third conveying channel 313.
[0104] In one embodiment, the converging space 321 is any one of a concave cavity, a receiving cavity or a space on the frame 1.
[0105] Further, please refer to Figures 1 to 2 0. As a specific embodiment of the pipeline for liquid detection provided by the present invention, the part of the first conveying channel 311 communicating with the intersection space 321 extends along the first horizontal straight-line extension direction, and the part of the second conveying channel 312 communicating with the intersection space 321 extends along the second horizontal straight-line extension direction; the part of the third conveying channel 313 communicating with the intersection space 321 extends along the second horizontal straight-line extension direction; the first pusher 322 includes: a second electric telescopic rod 3221 and a first moving component arranged on the frame 1; the second electric telescopic rod 3221 has a second telescopic part 32211 that can telescopically move in the first horizontal straight-line extension direction; the first moving component can move the second electric telescopic rod 3221 in the second horizontal straight-line extension direction. In this way, the telescopic direction of the second telescopic part 32211 is the same as the extension direction of the position where the first conveying channel 311 communicates with the intersection space 321, which is convenient for the second telescopic part 32211 to push the moving platform 21 in the intersection space 321 into the first conveying channel 311; the second electric telescopic rod 3221 can move along a direction perpendicular to the telescopic direction of the second telescopic part 32211 under the drive of the first moving component, so that the second telescopic part 32211 can dial the moving platform 21 in the intersection space 321 into the second conveying channel 312, or so that the second telescopic part 32211 can dial the moving platform 21 in the intersection space 321 into the third conveying channel 313.
[0106] Further, please refer to Figures 1 to 2 0. As a specific embodiment of the pipeline for liquid detection provided by the present invention, the first moving component includes: a first slide rail 323 arranged on the frame 1, a first lead screw 324 rotatably arranged on the frame 1 and parallel to the first slide rail 323, a first motor 325 arranged on the frame 1 and used to drive the first lead screw 324 to rotate, and a first slider 326 slid on the first slide rail 323; the second electric telescopic rod 3221 is arranged on the first slider 326; the first slide rail 323 extends along the second horizontal straight-line extension direction. In this way, the first motor 325 drives the first lead screw 324 to rotate, the first lead screw 324 can drive the first slider 326 to move along the first slide rail 323, and the first slide rail 323 can drive the first electric push rod to move when it moves.
[0107] In one embodiment, the "lead screw" in the present application refers to: a rod body with an external thread.
[0108] Further, please refer to Figures 1 to 20. As a specific embodiment of the pipeline for liquid detection provided by the present invention, the driving mechanism includes: a first driving component disposed on the frame 1 and used to drive the moving table 21 to move along the first conveying channel 311, a second driving component disposed on the frame 1 and used to drive the moving table 21 to move along the second conveying channel 312, and a third driving component disposed on the frame 1 and used to drive the moving table 21 to move along the third conveying channel 313.
[0109] Further, please refer to Figures 1 to 2 0. As a specific embodiment of the pipeline for liquid detection provided by the present invention, the moving table 21 has a second tooth portion 211; the first driving component includes: a first endless rack 331; the first endless rack 331 has a first tooth belt 3311 parallel to the first conveying channel 311; when the moving table 21 is located in the first conveying channel 311, the second tooth portion 211 meshes with the first tooth belt 3311; the second driving component includes: a second endless rack; the second endless rack has a second tooth belt 332 parallel to the second conveying channel 312; when the moving table 21 is located in the second conveying channel 312, the second tooth portion 211 meshes with the second tooth belt 332; the third driving component includes: a third endless rack; the third endless rack has a third tooth belt 333 parallel to the third conveying channel 313; when the moving table 21 is located in the third conveying channel 313, the second tooth portion 211 meshes with the third tooth belt 333. Thus, since the first tooth belt 3311 is parallel to the conveying channel, the second tooth portion 211 on the moving table 21 meshes with the first tooth belt 3311, so that when the first tooth belt 3311 moves, it can drive the moving table 21 to move; since the second tooth belt 332 is parallel to the conveying channel, the first tooth portion 373 on the moving table 21 meshes with the second tooth belt 332, so that when the second tooth belt 332 moves, it can drive the moving table 21 to move; since the third tooth belt 333 is parallel to the conveying channel, the third tooth portion on the moving table 21 meshes with the third tooth belt 333, so that when the third tooth belt 333 moves, it can drive the moving table 21 to move.
[0110] Further, please refer to Figures 1 to 20. As a specific embodiment of the pipeline for liquid detection provided by the present invention, it further includes: the first guide rail 341 and the second guide rail 342 are arranged in parallel at intervals; the first guide rail 341 and the second guide rail 342 are respectively arranged on the frame body 1; the first conveying channel 311 is formed between the first guide rail 341 and the second guide rail 342; the outer surface of the first guide rail 341 has a first rib 3411 extending along the first guide rail 341, and the outer surface of the second guide rail 342 has a second rib 3421 extending along the second guide rail 342; the first end of the moving table 21 has a first groove 212, and the second end of the moving table 21 has a second groove 213; the first rib 3411 can be clamped in the first groove 212, and the second rib 3421 can be clamped in the second groove 213. In this way, the moving table 21 can move under the restriction of the first guide rail 341 and the second guide rail 342. The first rib 3411 of the first guide rail 341 is clamped in the first groove 212 on the moving table 21, and the second rib 3421 of the second guide rail 342 is clamped in the second groove 213 on the moving table 21, reducing the shaking of the moving table 21 during the moving process.
[0111] Further, please refer to Figures 1 to 2 0. As a specific embodiment of the pipeline for liquid detection provided by the present invention, it further includes: it further includes: the third guide rail and the fourth guide rail are arranged in parallel at intervals; the third guide rail and the fourth guide rail are respectively arranged on the frame body 1; the second conveying channel 312 is formed between the third guide rail and the fourth guide rail; the outer surface of the third guide rail has a third rib extending along the third guide rail, and the outer surface of the fourth guide rail has a fourth rib extending along the fourth guide rail; the third rib can be clamped in the first groove 212, and the fourth rib can be clamped in the second groove 213. In this way, the moving table 21 can move under the restriction of the third guide rail and the fourth guide rail. The third rib of the third guide rail is clamped in the first groove 212 on the moving table 21, and the fourth rib of the fourth guide rail is clamped in the second groove 213 on the moving table 21, reducing the shaking of the moving table 21 during the moving process.
[0112] Further, please refer to Figures 1 to 20. As a specific embodiment of the pipeline for liquid detection provided by the present invention, it further includes: a fifth guide rail and a sixth guide rail arranged in parallel at intervals; the fifth guide rail and the sixth guide rail are respectively arranged on the frame 1; a third conveying channel 313 is formed between the fifth guide rail and the sixth guide rail; the outer surface of the fifth guide rail has a fifth rib extending along the fifth guide rail, and the outer surface of the sixth guide rail has a sixth rib extending along the sixth guide rail; the fifth rib can be clamped in the first groove 212, and the sixth rib can be clamped in the second groove 213. In this way, the moving platform 21 can move under the limitation of the fifth guide rail and the sixth guide rail. The fifth rib of the fifth guide rail is clamped in the fifth groove on the moving platform 21, and the sixth rib of the sixth guide rail is clamped in the sixth groove on the moving platform 21, reducing the shaking of the moving platform 21 during the moving process.
[0113] Further, please refer to Figures 1 to 2 0. As a specific embodiment of the pipeline for liquid detection provided by the present invention, it further includes: a feeding mechanism for storing the liquid storage tube 6 and a first transfer device arranged on the frame 1 and used to transfer the liquid storage tube 6 on the feeding mechanism to the first conveying channel 311. In this way, the first transfer device can transfer the liquid storage tube 6 in the feeding mechanism to the moving platform 21.
[0114] Further, please refer to Figures 1 to 2 0. As a specific embodiment of the pipeline for liquid detection provided by the present invention, the first transfer device includes: a first gripper 47 for clamping the liquid storage tube 6 and a first transfer mechanism 48 for driving the first gripper 47 to move in the XYZ directions.
[0115] In one embodiment, the first transfer mechanism 48 includes: a first X slide rail arranged on the frame 1, a first X sliding table slid on the first X slide rail, a first X driver for driving the first X sliding table to slide, a first Y slide rail arranged on the first X sliding table, a first Y sliding table slid on the first Y slide rail, a first Y driver for driving the first Y sliding table to slide, a first Z slide rail arranged on the first Y sliding table, a first Z sliding table slid on the first Z slide rail, and a first Z driver for driving the first Z sliding table to slide; the first gripper 47 is arranged on the first Z sliding table.
[0116] In one embodiment, the first X driver includes: a first X lead screw rotatably arranged on the frame 1 and a first X motor for driving the first X lead screw to rotate; the first X sliding table is threadedly connected to the first X lead screw.
[0117] In one embodiment, the first Y driver includes: a first Y lead screw rotatably arranged on the first X sliding table and a first Y motor for driving the first Y lead screw to rotate; the first Y sliding table is threadedly connected to the first Y lead screw.
[0118] In one embodiment, the first Z-driver includes: a first Z lead screw rotatably provided on the first Y slide table and a first Z motor for driving the first Z lead screw to rotate; the first Z slide table is threadedly connected to the first Z lead screw.
[0119] Further, referring to Figures 1 to 2 FIG. 0, as a specific embodiment of the pipeline for liquid detection provided by the present invention, the feeding mechanism includes: a plurality of sliding members 41, a sample tray 43 for placing a liquid storage tube 6, a plurality of sample racks 42 provided on the sliding members 41 and for placing the sample tray 43, a seat body 44 provided on the frame body 1, and a driving unit provided on the frame body 1; the seat body 44 has a sliding channel 45 for the plurality of sliding members 41 to slide in a cycle, and the driving unit can drive the plurality of sliding members 41 to slide along the sliding channel 45; the plurality of sliding members 41 correspond to the plurality of sample racks 42 one by one. Thus, the seat body 44 is provided on the frame body 1, the seat body 44 has the sliding channel 45 for the sliding members 41 to slide in a cycle, the driving unit is provided on the frame body 1, and the driving unit can drive the sliding members 41 to slide in a cycle along the sliding channel 45, the sample racks 42 are provided on the sliding members 41, and the sample racks 42 can slide together with the sliding members 41; since the sample racks 42 can move cyclically with the sliding members 41, when the sample racks 42 move to any position, the user can place the sample tray 43 on the sample racks 42, or the user can also take the sample tray 43 off the sample racks 42; the number of the sliding members 41 and the sample racks 42 are both plural, the plurality of sliding members 41 correspond to the plurality of sample racks 42 one by one, and when placing the sample trays 43 on the plurality of sample racks 42, they are independent of each other, without the need to place (or take out) the sample trays 43 one by one in sequence on the plurality of sample racks 42, which greatly improves the working efficiency.
[0120] In one embodiment, since the plurality of sample racks 42 all move cyclically along the sliding channel 45, the user can select a first predetermined position through which any plurality of sample racks 42 pass in sequence, and the user can store and retrieve the sample trays 43 on the sample racks 42 respectively at the above-mentioned first predetermined position; since the plurality of sample racks 42 all move cyclically along the sliding channel 45, the user can select a second predetermined position through which any plurality of sample racks 42 pass in sequence, and the detection device can store and retrieve the sample trays 43 on the sample racks 42 respectively at the above-mentioned second predetermined position for detection.
[0121] In one embodiment, the sliding channel 45 can be any one of: a groove, a pipe, and a space.
[0122] In one embodiment, the sample tray 43 is provided with insertion holes, and the liquid storage tube 6 is inserted into the insertion holes.
[0123] In one embodiment, the plurality of sliding members 41 are arranged at intervals in sequence along the sliding channel 45.
[0124] In one embodiment, the sliding channel 45 is communicated at both ends.
[0125] Further, please refer to Figures 1 to 2 FIG. 0. As a specific embodiment of the pipeline for liquid detection provided by the present invention, the sliding channel 45 is in a circular closed shape. In this way, the sliding member 41 can slide along the closed path of the sliding channel 45 in a cycle, which is convenient for the user to access the sample tray 43 on the sample rack 42 at the same position.
[0126] In one embodiment, the sliding channel 45 is in a rounded rectangular closed shape.
[0127] Further, please refer to Figures 1 to 2 FIG. 0. As a specific embodiment of the pipeline for liquid detection provided by the present invention, the driving unit includes: a chain 461 disposed on the frame 1 and capable of circular movement, and a third driver for driving the circular movement of the chain 461; a plurality of sliding members 41 are fixedly arranged on the chain 461 at intervals in sequence. In this way, the driver drives the chain 461 to move in a cycle, and a plurality of sliding members 41 are fixedly arranged on the chain 461 at intervals in sequence, so that the sliding member 41 can move under the traction of the chain 461.
[0128] Further, please refer to Figures 1 to 2 FIG. 0. As a specific embodiment of the pipeline for liquid detection provided by the present invention, the third driver includes: a second motor 462 and a gear 463; the gear 463 is in transmission connection with the output shaft of the second motor 462; the gear 463 is engaged with the chain 461. In this way, the motor drives the gear 463 to rotate through the output shaft, and the gear 463 drives the chain 461 to move.
[0129] In one embodiment, the second motor 462 and the gear 463 are respectively disposed on the frame 1.
[0130] Further, please refer to Figures 1 to 2 FIG. 0. As a specific embodiment of the pipeline for liquid detection provided by the present invention, the number of the gears 463 is multiple, and the chain 461 is sleeved and engaged with the multiple gears 463; the output shaft of the second motor 462 is in transmission connection with one of the gears 463. In this way, the chain 461 is engaged with the multiple gears 463, which is convenient for the conveyance of the chain 461. The output shaft of the motor can drive one of the gears 463 to rotate to drive the entire chain 461 to move.
[0131] Further, please refer to Figures 1 to 2 FIG. 0. As a specific embodiment of the pipeline for liquid detection provided by the present invention, the number of the gears 463 is four; the trajectory of the chain 461 is in a rounded rectangular shape, and the four gears 463 are respectively engaged with the chain 461 at the corresponding positions.
[0132] Further, please refer to Figures 1 to 2 FIG. 0. As a specific embodiment of the pipeline for liquid detection provided by the present invention, the sample rack 42 has a placement cavity 421 with the bottom surface facing upward and for placing the sample tray 43; when the sample rack 42 moves with the sliding member 41, the bottom surface of the placement cavity 421 remains facing upward. In this way, the sample tray 43 is more stable when placed in the placement cavity 421.
[0133] Further, please refer to Figures 1 to 2 FIG. 0. As a specific embodiment of the pipeline for liquid detection provided by the present invention, the side wall of the placement cavity 421 has an opening 422 for the sample tray 43 to slide out. In this way, it is convenient for the sample tray 43 to slide out (or into) from one side of the placement cavity 421.
[0134] Further, please refer to Figures 1 to 2 FIG. 0. As a specific embodiment of the pipeline for liquid detection provided by the present invention, a channel 423 is formed on the bottom wall of the placement cavity 421. In this way, the weight of the sample rack 42 can be reduced.
[0135] In one embodiment, a snap mechanism is provided in the placement cavity 421, and the sample tray 43 is fixed in the placement cavity 421 through the snap mechanism.
[0136] In one embodiment, the base body 44 includes: a first track 441 and a second track 442 arranged in parallel at intervals; a sliding channel 45 is formed between the first track 441 and the second track 442; on the outer surface of the first track 441 between the first track 441 and the second track 442, there is a first groove 212 extending along the first track 441, and on the outer surface of the second track 442 between the first track 441 and the second track 442, there is a second groove 213 extending along the second track 442; the first end of the sliding member 41 is slidably arranged in the first groove 212, and the second end of the sliding member 41 is slidably arranged in the second groove 213. In this way, the sliding channel 45 is formed between the first track 441 and the second track 442, so that the sliding member 41 can slide between the first track 441 and the second track 442; one end of the sliding member 41 is slidably arranged in the first groove 212 on the surface of the first track 441, and the other end of the sliding member 41 is slidably arranged in the second groove 213 on the surface of the second track 442, so that the sliding member 41 is more stable during the sliding process.
[0137] Further, please refer to Figures 1 to 20. As a specific embodiment of the pipeline for liquid detection provided by the present invention, it further includes: a clamping mechanism disposed on the frame 1 and used to clamp the liquid storage tube 6 at the storage position, a clamping and opening device 35 that can rotate and is used to clamp the cover 61 of the liquid storage tube 6 in the storage position, and a second transfer mechanism 39 disposed on the frame 1 and used to move the clamping and opening device 35. When the moving table 21 moves to the second position in the second conveying channel 312, the clamping mechanism can clamp the liquid storage tube 6 at the storage position. Thus, when the moving table 21 moves to the second position, the clamping mechanism can clamp the liquid storage tube 6 located at the storage position to prevent the liquid storage tube 6 from moving or rotating by itself. The second transfer mechanism 39 can move the clamping and opening device 35 to the required position so that the clamping and opening device 35 can clamp the cover 61. After the clamping and opening device 35 clamps the cover 61 of the liquid storage tube 6, the clamping and opening device 35 rotates the cover 61 to screw the cover 61 off the liquid storage tube 6. After the cover 61 is screwed off by the clamping and opening device 35, the clamping and opening device 35 can carry the cover 61 and transfer it to other positions through the second transfer mechanism 39. After the cover 61 is removed by the clamping and opening device 35, the user can obtain the liquid from the liquid storage tube 6 for subsequent detection (in one embodiment, the way for the user to obtain the liquid in the liquid storage tube 6 is: the pipette 371 inserts the TIP (TIP: the tip of the pipette 371) head and then automatically sucks the liquid in the liquid storage tube 6). The cover 61 of the liquid storage tube 6 does not need to be manually removed during the removal process, improving the work efficiency. After the user takes the liquid in the liquid storage tube 6, the clamping and opening device 35 can carry the cover 61 and reinstall the cover 61 onto the liquid storage tube 6.
[0138] In one embodiment, the clamping and opening device 35 is an electric rotary jaw.
[0139] Further, please refer to Figures 1 to 2 0. As a specific embodiment of the pipeline for liquid detection provided by the present invention, the clamping mechanism includes: a first clamping part 361, a second clamping part 362, and a fourth driver disposed on the frame 1 and used to drive the first clamping part 361 and the second clamping part 362 to move closer synchronously and clamp the liquid storage tube 6 at the storage position. Thus, the first driver 375 drives the first clamping part 361 and the second clamping part 362 to move closer synchronously to clamp the liquid storage tube 6.
[0140] Further, please refer to Figures 1 to 20. As a specific embodiment of the pipeline for liquid detection provided by the present invention, the fourth driver includes: a second slide rail 3631 provided on the frame 1, a third slide rail 3632 provided on the frame 1 and parallel to the second slide rail 3631, a second lead screw 364 rotatably provided on the frame 1 and parallel to the second slide rail 3631, a third motor 365 provided on the frame 1 for driving the second lead screw 364 to rotate, a second slider 366 slidably provided on the second slide rail 3631, and a third slider 367 slidably provided on the third slide rail 3632; a first clamping portion 361 is provided on the second slider 366, and a second clamping portion 362 is provided on the third slider 367; the second lead screw 364 includes: a first screw rod 3641 and a second screw rod 3642; the first screw rod 3641 and the second screw rod 3642 are coaxially provided, and the thread spiral directions of the first screw rod 3641 and the second screw rod 3642 are opposite; the second slider 366 is threadedly connected to the first screw rod 3641, and the third slider 367 is threadedly connected to the second screw rod 3642. Thus, a second slide rail 3631 and a third slide rail 3632 are provided on the frame 1, the first slider 326 is slidably provided on the second slide rail 3631, and the third slider 367 is slidably provided on the third slide rail 3632; the first motor 325 can drive the second lead screw 364 to rotate, the second lead screw 364 includes the first screw rod 3641 and the second screw rod 3642, the second slider 366 is threadedly connected to the first screw rod 3641, and the third slider 367 is threadedly connected to the second screw rod 3642; the thread directions of the first screw rod 3641 and the second screw rod 3642 are opposite, so that when the second lead screw 364 rotates, the first slider 326 and the third slider 367 can approach (or move away from) each other synchronously, and when the first slider 326 and the third slider 367 approach synchronously, the liquid storage tube 6 can be clamped.
[0141] In one embodiment, the second slider 366 can be a single element or formed by connecting multiple elements. In one embodiment, the second slider 366 includes: a first sliding portion 3661 and a first connecting portion 3662; the first sliding portion 3661 is detachably fixed to the first connecting portion 3662; the first sliding portion 3661 is slidably provided on the first slide rail 431, and the first clamping portion 361 is provided on the first connecting portion 3662.
[0142] In one embodiment, the third slider 367 can be a single element or formed by connecting multiple elements. In one embodiment, the third slider 367 includes: a second sliding portion 3671 and a second connecting portion 3672; the second sliding portion 3671 is detachably fixed to the second connecting portion 3672; the second sliding portion 3671 is slidably provided on the second slide rail 432, and the second clamping portion 362 is provided on the second connecting portion 3672.
[0143] Further, please refer to Figures 1 to 20. As a specific implementation of the pipeline for liquid detection provided by the present invention, the first clamping portion 361 has a first clamping groove, and the second clamping portion 362 has a second clamping groove; when the first clamping portion 361 and the second clamping portion 362 approach each other, the liquid storage tube 6 on the storage position can be clamped between the inner walls of the first clamping groove and the second clamping groove. In this way, when the liquid storage tube 6 is clamped between the inner walls of the first clamping groove and the second clamping groove, the liquid storage tube 6 is not easily separated from between the first clamping portion 361 and the second clamping portion 362.
[0144] Further, please refer to Figures 1 to 2 0. As a specific implementation of the pipeline for liquid detection provided by the present invention, the clamping and opening device 35 is: a rotating electric claw.
[0145] In one embodiment, the second transfer mechanism 39 includes: a second X slide rail provided on the frame 1, a second X sliding table slid on the second X slide rail, a second Y slide rail provided on the second X sliding table, a second Y left sliding table slid on the second Y slide rail, a second X driver for driving the second X sliding table to slide, and a second Y left driver for driving the second Y left sliding table to move; the clamping and opening device 35 is provided on the second Y left sliding table; the second X driver includes: a second X lead screw rotatably provided on the frame 1 and a second X motor for driving the second X lead screw to rotate; the second X motor is provided on the frame 1; the second X lead screw is arranged parallel to the second X slide rail, and the second X lead screw is threadedly connected to the second X sliding table; the second Y left driver includes: a second Y left lead screw rotatably provided on the second X sliding table and a second Y left motor for driving the second Y left lead screw to rotate; the second Y left motor is provided on the second X sliding table; the second Y left lead screw is arranged parallel to the second Y slide rail, and the second Y left lead screw is threadedly connected to the second Y left sliding table. In this way, the second X sliding table slides on the second X slide rail, the second X lead screw is threadedly connected to the second X sliding table, and when the second X motor drives the second X lead screw to rotate, the second X lead screw can drive the second X sliding table to slide; the second Y left sliding table slides on the second Y slide rail, the second Y left lead screw is threadedly connected to the second Y left sliding table, and when the second Y left motor drives the second Y left lead screw to rotate, the second Y left lead screw can drive the second Y left sliding table to slide; the clamping and opening device 35 can move in the X (and Y) directions through the second X sliding table and the second Y left sliding table.
[0146] In one embodiment, it further includes: a first Z slide rail disposed on the second Y left slide table, a second Z left slide table slidably disposed on the first Z slide rail, a first Z lead screw rotatably disposed on the second Y left slide table, and a first Z motor for driving the first Z lead screw to rotate; the first Z motor is disposed on the second Y left slide table; the first Z lead screw is arranged in parallel with the first Z slide rail, and the first Z lead screw is threadedly connected to the second Z left slide table; the clamping and lid-opening device 35 is disposed on the second Z left slide table. Thus, the second Z left slide table is slidably disposed on the first Z slide rail, the first Z lead screw is threadedly connected to the second Z left slide table, and when the first Z motor drives the first Z lead screw to rotate, the first Z lead screw can drive the second Z left slide table to slide; the clamping and lid-opening device 35 can move in the X (and Y, Z) directions through the second Z left slide table, the second X slide table, and the second Y left slide table.
[0147] In one embodiment, the clamping and lid-opening device 35 includes: a jaw for clamping the lid 61 and a rotating unit for rotating the jaw; the jaw and the rotating unit are respectively disposed on the second Z left slide table. Thus, the jaw can clamp the lid 61, and the rotating unit can drive the jaw to rotate to screw the lid 61 off the liquid storage tube 6; both the jaw and the rotating unit can move with the second Z left slide table.
[0148] In one embodiment, it further includes: a pipette 371 for sucking the liquid in the liquid storage tube 6 at the storage position, a second Y right slide table slidably disposed on the second Y slide rail, and a fifth driver for driving the second Y right slide table to move; the pipette 371 is disposed on the second Y right slide table; the fifth driver includes: a second Y right lead screw rotatably disposed on the second X slide table and a second Y right motor for driving the second Y right lead screw to rotate; the second Y right motor is disposed on the second X slide table; the second Y right lead screw is arranged in parallel with the second Y slide rail, and the second Y right lead screw is threadedly connected to the second Y right slide table. Thus, the second Y right slide table is slidably disposed on the second Y slide rail, the second Y right lead screw is threadedly connected to the second Y right slide table, and when the second Y right motor drives the second Y right lead screw to rotate, the second Y right lead screw can drive the second Y right slide table to slide; the pipette 371 can move in the X (and Y) directions through the second X slide table and the second Y right slide table.
[0149] In one embodiment, it further includes: a second Z rail disposed on the second Y right sliding table, a second Z right sliding table slidably disposed on the second Z rail, a second Z lead screw rotatably disposed on the second Y right sliding table, and a second Z motor for driving the rotation of the second Z lead screw; the second Z motor is disposed on the second Y right sliding table; the second Z lead screw is disposed parallel to the second Z rail, and the second Z lead screw is threadedly connected to the second Z right sliding table; the pipette 371 is disposed on the second Z right sliding table. In this way, the second Z right sliding table is slidably disposed on the second Z rail, the second Z lead screw is threadedly connected to the second Z right sliding table, and when the second Z motor drives the second Z lead screw to rotate, the second Z lead screw can drive the second Z right sliding table to slide; the clamping and opening device 35 can move in the X (and Y, Z) directions through the second Z right sliding table, the second X sliding table, and the second Y left sliding table.
[0150] Further, please refer to Figures 1 to 2 0. As a specific embodiment of the liquid detection pipeline provided by the present invention, it further includes: a centrifuge 381; the second transfer mechanism 39 can transfer the liquid storage tube 6 into the centrifuge 381.
[0151] In one embodiment, when the liquid storage tube 6 with the lid 61 is placed into the centrifuge 381, the centrifuge 381 can remove the lid after centrifugation.
[0152] Further, please refer to Figures 1 to 2 0. As a specific embodiment of the liquid detection pipeline provided by the present invention, a waiting tray 3811 for placing the liquid storage tube 6 is provided on the top of the outer shell of the centrifuge 381; the second transfer mechanism 39 can transfer the liquid storage tube 6 to the waiting tray 3811. In this way, the liquid storage tube 6 can be first placed on the waiting tray 3811 and then placed into the centrifuge 381.
[0153] Further, please refer to Figures 1 to 2 0. As a specific embodiment of the liquid detection pipeline provided by the present invention, it further includes: a lid storage area 382 disposed on the frame 1 and used for placing the lid 61. In this way, it is convenient for storing the lid 61.
[0154] Further, please refer to Figures 1 to 2 0. As a specific embodiment of the liquid detection pipeline provided by the present invention, it further includes: a pipette 371 for sucking the liquid in the liquid storage tube 6 at the storage position; the second transfer mechanism 39 can drive the pipette 371 to move in the XYZ directions. In this way, the pipette 371 can move in the XYZ directions.
[0155] Further, please refer to Figures 1 to 20. As a specific implementation of the pipeline for liquid detection provided by the present invention, it further includes: a nucleic acid extraction and detection unit 5, a loading platform 383 provided on the frame 1, a storage container 384 detachably provided on the loading platform 383 and used for temporarily storing liquid, and a third transfer mechanism 56 for transferring the storage container 384 into the nucleic acid extraction and detection unit 5 for nucleic acid detection; the pipette 371 can transfer the liquid in the liquid storage tube 6 to the storage container 384 through the second transfer mechanism 39. Thus, the third transfer mechanism 56 can transfer the storage container 384 into the nucleic acid extraction and detection unit 5 for nucleic acid detection; the liquid in the liquid storage tube 6 can be transferred to the storage container 384 by the pipette 371.
[0156] In one embodiment, the third transfer mechanism 56 is provided on the frame 1.
[0157] Further, please refer to Figures 1 to 2 0. As a specific implementation of the pipeline for liquid detection provided by the present invention, the storage container 384 has a protective cover 385; the clamping and opening device 35 can remove and install the protective cover 385.
[0158] Further, please refer to Figures 1 to 2 0. As a specific implementation of the pipeline for liquid detection provided by the present invention, the loading platform 383 can approach or move away from the nucleic acid extraction and detection unit 5 through the second moving component.
[0159] In one embodiment, the second moving component includes: a loading lead screw 3831 rotatably provided on the frame 1, a loading motor 3832 provided on the frame 1, and a loading slide rail 3833 provided on the frame 1; the loading platform 383 slides on the loading slide rail 3833, and the loading lead screw 3831 is threadedly connected to the loading platform 383; the loading motor 3832 drives the loading lead screw 3831 to rotate to drive the loading platform 383 to slide along the loading slide rail 3833.
[0160] Further, please refer to Figures 1 to 2 0. As a specific implementation of the pipeline for liquid detection provided by the present invention, it further includes: a stacking platform 386 for stacking the storage containers 384 and a lifting mechanism for driving the stacking platform 386 to move up and down; the third transfer mechanism 56 can transfer the objects on the stacking platform 386.
[0161] In one embodiment, the lifting mechanism includes a lifting lead screw 3861 rotatably arranged on the frame 1, a lifting motor 3862 arranged on the frame 1, and a lifting slide rail 3863 arranged on the frame 1; the stacking platform 386 is slidably arranged on the lifting slide rail 3863, and the lifting lead screw 3861 is threadedly connected to the stacking platform 386; the lifting motor 3862 drives the lifting lead screw 3861 to rotate, which can drive the stacking platform 386 to slide along the lifting slide rail 3863.
[0162] In one embodiment, it further includes a waste bin; the third transfer mechanism 56 can transfer the storage container 384 into the waste bin.
[0163] In one embodiment, a TIP head (TIP head: the tip of the pipette 371) bracket; the pipette 371 can pick up the TIP head from the TIP head bracket to aspirate liquid.
[0164] In one embodiment, it further includes a TIP head waste bin; the pipette 371 can throw the used TIP head into the waste bin through the second moving mechanism.
[0165] Furthermore, the nucleic acid extraction and detection unit 5 includes a bracket 51 arranged on the frame 1, an amplification device 52, an extraction device 53, a fluorescence detection device 54, and a driving device 55; the amplification device 52 is arranged on the bracket 51 and can be used for temperature adjustment; the extraction device 53 is installed on the amplification device 52. The extraction device 53 includes a test tube installation component 531, a first driving member 532, and a magnetic attracting member 533. The test tube installation component 531 has a first installation hole 5311, the magnetic attracting member 533 is arranged on the hole wall of the first installation hole 5311, and the first driving member 532 is installed on the bracket 51 and is used to drive the test tube installation component 531 to rotate, so as to drive the magnetic attracting member 533 to rotate around the outer periphery of the test tube located in the test tube installation component 531 and perform nucleic acid extraction; the third transfer mechanism 56 can transfer the storage container 384 into the first installation hole 5311; the fluorescence detection device 54 is installed on the bracket 51 and is used for fluorescence detection of the test tube; and the driving device 55 is installed on the bracket 51, and the output end of the driving device 55 is connected to the amplification device 52 and is used to drive the amplification device 52 and the extraction device 53 to rotate relative to the fluorescence detection device 54.
[0166] Thus, the bracket 51 serves as an installation structure to carry the amplification device 52, the extraction device 53, the fluorescence detection device 54, and the driving device 55; the extraction device 53 is used to extract nucleic acids from the nucleic acid solution in the test tube. In this embodiment, magnetic beads are placed in the test tube, and the magnetic beads are used to fully bind to the lysed nucleic acids. The extraction device 53 includes a test tube installation component 531, a first driving member 532, and a magnetic attraction member 533. The test tube installation component 531 has a first installation hole 5311 for placing the test tube. The magnetic attraction member 533 is disposed on the hole wall of the first installation hole 5311. The magnetic attraction member 533 provides a magnetic attraction force to adsorb the magnetic beads in the test tube. The first driving member 532 is installed on the bracket 51 and is used to drive the test tube installation component 531 to rotate, so as to drive the magnetic attraction member 533 to rotate around the outer periphery of the test tube located in the test tube installation component 531. The magnetic beads rotate accordingly, driving the nucleic acids to complete washing and purification in the test tube, so as to complete the extraction of nucleic acids; the extraction device 53 is installed on the amplification device 52, and the amplification device 52 is used to adjust the temperature at the bottom of the test tube to achieve the amplification of the nucleic acids in the test tube; in this embodiment, the fluorescence detection device 54 and the driving device 55 are installed on the bracket 51, and the output end of the driving device 55 is connected to the amplification device 52. The amplification device 52 is disposed on the bracket 51 through the driving device 55. The driving device 55 is used to drive the amplification device 52 and the extraction device 53 to rotate relative to the fluorescence detection device 54, and the fluorescence detection device 54 emits light to the test tube to perform fluorescence detection on the nucleic acids in the test tube.
[0167] In one embodiment, the liquid in the liquid storage tube 6 is first transferred to the storage container 384, and the storage container 384 is transferred by the third transfer mechanism 56.
[0168] In this embodiment, the functions of nucleic acid extraction, amplification, and fluorescence detection are integrated into one, eliminating the need to perform nucleic acid extraction, amplification, and fluorescence detection operations in laboratories in different partitions, improving efficiency, shortening the detection time, and avoiding the problem of aerosol contamination caused by the need to carry to different partitions for work.
[0169] Please refer to the figure. The extraction device 53 further includes a gear disk. The test tube mounting assembly 531 includes a gear member. The output shaft of the first driving member 532 passes through the amplification device 52 and is connected to the gear disk. The gear member has a first mounting hole 5311. The gear disk meshes with the gear member, and the magnetic attraction member 533 is arranged on the gear member. Thus, the extraction device 53 further includes a gear disk. A first through hole is formed in the gear disk, and the output shaft of the first driving member 532 passes through the amplification device 52 and is fitted and installed with the first through hole of the gear disk to realize the connection between the output shaft of the first driving member 532 and the gear disk. The test tube mounting assembly 531 includes a gear member. The gear disk meshes with the gear member. The gear member has a first mounting hole 5311. The magnetic attraction member 533 is arranged on the hole wall of the first mounting hole 5311 of the gear member. When a test tube is placed on the first mounting hole 5311, when the first driving member 532 drives the rotation of the gear disk to drive the rotation of the gear member, the magnetic beads in the test tube are driven to rotate accordingly.
[0170] In one embodiment, the gear member includes a columnar main body. The first mounting hole 5311 penetrating through both ends of the main body is formed on the main body. A ratchet is arranged at one end of the main body and meshes with the gear disk. The ratchet is arranged on the circumferential side of the main body. A second mounting hole is formed in the hole wall of the first mounting hole 5311, and the magnetic attraction member 533 is arranged in the second mounting hole. The magnetic beads in the test tube are adsorbed by the magnetic attraction force of the magnetic attraction member 533. When the gear disk drives the main body to rotate, the position of the magnetic attraction member 533 also moves with the rotation of the main body, and then drives the magnetic beads in the test tube to rotate accordingly, thereby completing the nucleic acid extraction process. Preferably, the magnetic attraction member 533 is a magnet.
[0171] In one embodiment, the extraction device 53 further includes a chassis and a top plate. A receiving cavity is formed between the chassis and the top plate. The gear disk is arranged in the receiving cavity. The chassis is arranged on the amplification device 52, and a third mounting hole for the bottom of the test tube to pass through is formed on the chassis. Thus, the extraction device 53 further includes a chassis and a top plate. A receiving cavity is formed between the chassis and the top plate. The gear disk is arranged in the receiving cavity. In this embodiment, a second through hole is formed on the chassis for the output shaft of the first driving member 532 to pass through and be connected to the gear disk. The bottom of the gear member is fitted and installed with the chassis, and the top of the gear member is fitted and installed with the top plate.
[0172] In this embodiment, a third mounting hole for the bottom of the test tube to pass through is formed on the chassis. At this time, the part of the bottom of the test tube passing through the third mounting hole is exposed outside the extraction device 53, and this part is located above the amplification device 52. The amplification device 52 performs temperature regulation such as heating and cooling on this part to realize nucleic acid amplification.
[0173] Understandably, bolt holes are provided at corresponding positions on the top plate and the bottom plate, and the two are connected by bolts. In addition, hollow mounting posts can also be provided on the bottom plate, and the bolts pass through the bolt holes of the top plate and are connected to the mounting posts. The specific connection method is not limited herein.
[0174] In one embodiment, the fourth mounting holes are provided on both the side surface of the gear member facing the bottom plate and the side surface facing the top plate, and balls are arranged in the fourth mounting holes. The test tube mounting assembly 531 further includes a fitting, which is arranged on the bottom plate. A first chute is provided on the side surface of the fitting facing the top plate, and the third mounting hole penetrates through the first chute; a second chute corresponding to the gear member is provided on the side surface of the top plate facing the bottom plate; the gear member is arranged between the top plate and the fitting, the gear member and the fitting are correspondingly arranged, and the gear member can rotate on the first chute and the second chute through the balls. In this way, the test tube mounting assembly 531 further includes a fitting, which is arranged on the bottom plate, the gear member is arranged between the top plate and the fitting, and the gear member and the fitting are correspondingly arranged. In addition, the fourth mounting holes are provided on the side surface of the gear member facing the bottom plate, balls are arranged in the fourth mounting holes, a first chute is provided on the side surface of the fitting facing the top plate, and the gear member can rotate on the first chute through the balls. When the gear member rotates, the balls rotate along the shape of the first chute. In this embodiment, by providing the fitting, it not only provides a supporting effect for the installation of the gear member, but also can prevent the gear member from moving smoothly when rotating. In this embodiment, the third mounting hole penetrates through the first chute for the bottom of the test tube to pass through.
[0175] Understandably, the fourth mounting holes are provided on the side surface of the gear member facing the top plate in this embodiment, and the second chute corresponding to the gear member is provided on the side surface of the top plate facing the bottom plate. The gear member can rotate on the second chute through the balls. When the gear member rotates, the balls rotate along the shape of the second chute.
[0176] It should be noted that multiple fourth mounting holes are provided at the bottom of the gear member in this embodiment to balance the mounting heights of various parts of the gear member and the fitting; in addition, multiple fourth mounting holes are provided at the top of the gear member to balance the mounting heights of various parts of the gear member and the second chute.
[0177] In one embodiment, there are multiple test tube mounting components 531. The multiple test tube mounting components 531 are arranged around the circumferential side of the gear disk to form a test tube mounting group. Among them, the number of test tube mounting groups is n, and the n groups of test tube mounting groups are arranged in sequence along the radial direction of the gear disk, where n≥1. In this way, there are multiple test tube mounting components 531. The multiple test tube mounting components 531 are arranged around the circumferential side of the gear disk to form a test tube mounting group. Multiple gear members are installed on the circumferential side of the gear disk in an annular arrangement, and the gear members are respectively meshed with the gear disk. This method can save space during installation. At the same time, this method can drive multiple gear members to rotate synchronously with one gear disk, with fewer transmission times and high efficiency. In addition, the situation where the operation of the entire nucleic acid extraction and amplification integrated detection device is affected by the damage of one gear member will not occur, enhancing the stability of the nucleic acid extraction and amplification integrated detection device. On the other hand, the annular arrangement structure is simpler and more compact, making the heating of the amplification device 52 more concentrated, enabling more uniform heating, with a smaller temperature difference between each test tube, and improving the uniformity. Among them, the number of test tube mounting groups is n, and the n groups of test tube mounting groups are arranged in sequence along the radial direction of the gear disk, where n≥1.
[0178] When n is 1, the gear members are wound around the circumferential side of the gear disk to form a circular structure. When n is 2, the gear members are wound around the circumferential side of the gear disk to form a circular structure, which is the inner gear ring. Multiple gear members are wound outside the inner gear ring to form another circular structure, which is the outer gear ring. At this time, the outer gear ring is meshed with the inner gear ring. The rotation of the gear disk can drive the rotation of the inner gear ring, and the outer gear ring will rotate accordingly, realizing the synchronous rotation of the inner gear ring and the outer gear ring.
[0179] It can be understood that the gear members located on the outer gear ring are meshed with two adjacent gear members located on the inner gear ring, that is, the gear members located on the outer gear ring are staggered with the gear members located on the inner gear ring to achieve synchronous transmission. n can also be 3, 4 or more, and the setting method of the gear members can be inferred by analogy. Preferably, n in this embodiment is 2, and each gear ring has 16 gear members, which can simultaneously realize the extraction and amplification of nucleic acids of multiple samples, improving the efficiency of nucleic acid extraction and amplification, and achieving a single-module multi-flux setting in terms of structure.
[0180] The above are only the preferred embodiments of the present invention. It should be noted that for those of ordinary skill in the art, without departing from the technical principle of the present invention, several improvements and replacements can still be made, and these improvements and replacements should also be regarded as the protection scope of the present invention.
Claims
1. An assembly line for liquid detection, characterized in that, include: A frame, a mobile station, a first conveying channel arranged on the frame and used to convey the mobile station, a second conveying channel arranged on the frame and used to convey the mobile station, a third conveying channel arranged on the frame and used to convey the mobile station, a diversion mechanism arranged on the frame, and a driving mechanism; a storage position for carrying a liquid storage tube is arranged on the mobile station; the driving mechanism can drive the mobile station to move along the first conveying channel, the second conveying channel, and the third conveying channel; the output end of the first conveying channel is connected with the input end of the second conveying channel and the input end of the third conveying channel respectively; the diversion mechanism can divert the mobile station in the first conveying channel to the second conveying channel or the third conveying channel; the output end of the second conveying channel is connected with the input end of the first conveying channel, and the output end of the third conveying channel is connected with the input end of the first conveying channel.
2. The pipeline for liquid detection according to claim 1, characterized in that, Also includes: A photographing mechanism disposed on the frame and used for photographing the liquid storage tube on the movable platform; When the movable platform moves to the first position in the first conveying channel, the photographing mechanism can photograph the liquid storage tube on the movable platform.
3. The pipeline for liquid detection according to claim 2, wherein, Also includes: Rotating a rotating table disposed on the moving table and a rotating mechanism for driving the rotating table to rotate; The storage position is arranged on the rotating platform; When the moving platform moves to the first position, the rotating mechanism can drive the rotating platform to rotate.
4. The pipeline for liquid detection according to claim 3, wherein The rotating shaft of the rotating table is arranged vertically.
5. The pipeline for liquid detection according to claim 3, wherein, The rotating mechanism includes: a first tooth portion arranged on the rotating platform, a spur rack extending in a straight direction, and a first driver arranged on the frame and used to drive the spur rack to move along the extending direction of the spur rack; the first tooth portion is arranged around the outer side of the rotating shaft of the rotating platform; when the moving platform moves to the first position, the spur rack can be separated from or engaged with the first tooth portion.
6. The pipeline for liquid detection according to claim 5, characterized in that, The first driver is a predetermined electric telescopic rod.
7. The pipeline for liquid detection according to claim 5, characterized in that, The spur rack is arranged perpendicular to an extending direction of the first conveying passage.
8. The pipeline for liquid detection according to claim 2, characterized in that, Also includes: A first electric telescopic rod, a stopper, and a second driver; The second driver is arranged on the frame; The first electric telescopic rod has a first telescopic portion that is telescopic along the first conveying channel and is located outside the moving path of the mobile platform; the stop portion is arranged on the first electric telescopic rod, and the second driver can drive the first electric telescopic rod to rotate around the axis of the first electric telescopic rod; when the first electric telescopic rod is rotated to a first angle, the stop portion is located on the moving path of the mobile platform to intercept the mobile platform at the first position; when the first electric telescopic rod is rotated to a second angle, the stop portion avoids the moving path of the mobile platform.
9. The pipeline for liquid detection according to claim 1, characterized in that, The shunting mechanism includes: a convergence space provided on the frame body and capable of placing the moving platform, and a first pusher; an output end of the first conveying channel is communicated with the convergence space, an input end of the second conveying channel and an input end of the third conveying channel are respectively communicated with the convergence space; the first pusher can push the moving platform in the convergence space into the second conveying channel or the third conveying channel.
10. The pipeline for liquid detection according to claim 9, characterized in that, A part of the first conveying channel communicated with the convergence space extends along a first horizontal straight-line extension direction, and a part of the second conveying channel communicated with the convergence space extends along a second horizontal straight-line extension direction; A part of the third conveying channel communicated with the convergence space extends along the second horizontal straight-line extension direction; The first pusher includes: a second electric telescopic rod and a first moving assembly provided on the frame body; the second electric telescopic rod has a second telescopic part capable of telescopic movement in the first horizontal straight-line extension direction; the first moving assembly can move the second electric telescopic rod in the second horizontal straight-line extension direction.
11. The pipeline for liquid detection according to claim 10, wherein, The first moving assembly includes: a first slide rail provided on the frame body, a first lead screw rotatably provided on the frame body and parallel to the first slide rail, a first motor provided on the frame body and used for driving the first lead screw to rotate, and a first slider slidably provided on the first slide rail; the second electric telescopic rod is provided on the first slider; the first slide rail extends along the second horizontal straight-line extension direction.
12. The pipeline for liquid detection according to claim 1, wherein The driving mechanism includes: a first driving assembly provided on the frame body and used for driving the moving platform to move along the first conveying channel, a second driving assembly provided on the frame body and used for driving the moving platform to move along the second conveying channel, and a third driving assembly provided on the frame body and used for driving the moving platform to move along the third conveying channel.
13. The assembly line for liquid detection according to claim 12, wherein the moving platform has a second tooth part; The first driving assembly includes: a first circulating rack; the first circulating rack has a first tooth belt parallel to the first conveying channel; when the moving platform is located in the first conveying channel, the second tooth part meshes with the first tooth belt; The second driving assembly includes: a second circulating rack; the second circulating rack has a second tooth belt parallel to the second conveying channel; when the moving platform is located in the second conveying channel, the second tooth part meshes with the second tooth belt; The third driving assembly includes: a third circulating rack; the third circulating rack has a third tooth belt parallel to the third conveying channel; when the moving platform is located in the third conveying channel, the second tooth part meshes with the third tooth belt.
14. The pipeline for liquid detection according to claim 1, characterized in that, It further includes: A first guide rail and a second guide rail which are arranged in parallel at intervals; the first guide rail and the second guide rail are respectively arranged on the frame body; a first conveying channel is formed between the first guide rail and the second guide rail; a first rib extending along the first guide rail is arranged on the outer surface of the first guide rail, and a second rib extending along the second guide rail is arranged on the outer surface of the second guide rail; a first groove is formed at the first end of the moving table, and a second groove is formed at the second end of the moving table; the first rib can be clamped in the first groove, and the second rib can be clamped in the second groove.
15. The pipeline for liquid detection according to claim 14, characterized in that, Further included are: a third guide rail and a fourth guide rail which are arranged in parallel at intervals; the third guide rail and the fourth guide rail are respectively arranged on the frame body; a second conveying channel is formed between the third guide rail and the fourth guide rail; a third rib extending along the third guide rail is arranged on the outer surface of the third guide rail, and a fourth rib extending along the fourth guide rail is arranged on the outer surface of the fourth guide rail; the third rib can be clamped in the first groove, and the fourth rib can be clamped in the second groove.
16. The pipeline for liquid detection according to claim 14, wherein Further included are: a fifth guide rail and a sixth guide rail which are arranged in parallel at intervals; the fifth guide rail and the sixth guide rail are respectively arranged on the frame body; a third conveying channel is formed between the fifth guide rail and the sixth guide rail; a fifth rib extending along the fifth guide rail is arranged on the outer surface of the fifth guide rail, and a sixth rib extending along the sixth guide rail is arranged on the outer surface of the sixth guide rail; the fifth rib can be clamped in the first groove, and the sixth rib can be clamped in the second groove.
17. The pipeline for liquid detection according to claim 1, characterized in that, Further included is: A feeding mechanism for storing the liquid storage tube and a first transfer device which is arranged on the frame body and is used for transferring the liquid storage tube on the feeding mechanism into the first conveying channel.
18. The pipeline for liquid detection according to claim 17, wherein, The first transfer device includes: a first gripper for gripping the liquid storage tube and a first transfer mechanism for driving the first gripper to move in the XYZ directions.
19. The pipeline for liquid detection according to claim 18, characterized in that, The feeding mechanism includes: a plurality of sliding members, a sample tray for placing the liquid storage tube, a plurality of sample racks which are arranged on the sliding members and are used for placing the sample tray, a seat body arranged on the frame body, and a driving unit arranged on the frame body; the seat body has a sliding channel for the plurality of sliding members to slide in a circulating manner, and the driving unit can drive the plurality of sliding members to slide along the sliding channel; the plurality of sliding members correspond to the plurality of sample racks one by one.
20. The pipelining for liquid detection according to claim 19, wherein The sliding channel is in a circular closed shape.
21. The pipeline for liquid detection according to claim 19, wherein The driving unit includes: a chain which is arranged on the frame body and can move in a circulating manner and a third driver for driving the chain to move in a circulating manner; the plurality of sliding members are sequentially and fixedly arranged on the chain at intervals.
22. The pipeline for liquid detection according to claim 21, wherein, The third driver includes: a second motor and a gear; the gear is in transmission connection with the output shaft of the second motor; the gear is engaged with the chain.
23. The pipeline for liquid detection according to claim 22, wherein The number of the gears is multiple, the chain is sleeved and engaged on the multiple gears; the output shaft of the second motor is in transmission connection with one of the gears.
24. The pipelining for liquid detection according to claim 23, characterized in that, The number of the gears is four; the trajectory of the chain is in the shape of a rounded rectangle, and the four gears are respectively meshed with the four corners of the chain.
25. The pipeline for liquid detection according to claim 19, characterized in that, The sample rack has a placement cavity with the bottom surface facing upward for placing the sample tray; when the sample rack moves with the sliding member, the bottom surface of the placement cavity remains facing upward.
26. The pipeline for liquid detection according to claim 25, characterized in that, An opening for the sample tray to slide out is provided on the side wall of the placement cavity.
27. The pipeline for liquid detection according to claim 25, wherein A channel is opened on the bottom wall of the placement cavity.
28. The pipeline for liquid detection according to claim 1, characterized in that, Further comprising: A clamping mechanism provided on the frame body for clamping the liquid storage tube at the storage position, a clamping and opening device for clamping the cover on the liquid storage tube in the storage position and rotatable, and a second transfer mechanism provided on the frame body for moving the clamping and opening device; when the moving table moves to the second position in the second conveying channel, the clamping mechanism can clamp the liquid storage tube at the storage position.
29. The assembly line for liquid detection according to claim 28, characterized in that, The clamping mechanism includes: a first clamping portion, a second clamping portion, and a fourth driver provided on the frame body for driving the first clamping portion and the second clamping portion to move closer synchronously and clamp the liquid storage tube at the storage position.
30. The pipeline for liquid detection according to claim 29, characterized in that, The fourth driver includes: a second slide rail provided on the frame body, a third slide rail provided on the frame body and parallel to the second slide rail, a second lead screw rotatably provided on the frame body and parallel to the second slide rail, a third motor provided on the frame body for driving the second lead screw to rotate, a second slider slidably provided on the second slide rail, and a third slider slidably provided on the third slide rail; the first clamping portion is provided on the second slider, and the second clamping portion is provided on the third slider; the second lead screw includes: a first screw rod and a second screw rod; the first screw rod and the second screw rod are coaxially arranged, and the thread spiral directions of the first screw rod and the second screw rod are opposite; the second slider is threadedly connected to the first screw rod, and the third slider is threadedly connected to the second screw rod.
31. The pipeline for liquid detection according to claim 29, characterized in that, The first clamping portion has a first clamping groove, and the second clamping portion has a second clamping groove; when the first clamping portion and the second clamping portion move closer to each other, the liquid storage tube at the storage position can be clamped between the inner walls of the first clamping groove and the second clamping groove.
32. The pipeline for liquid detection according to claim 29, wherein The clamping and opening device is: a rotary electric gripper.
33. The pipeline for liquid detection according to claim 29, wherein, Further comprising: A centrifuge; the second transfer mechanism can transfer the liquid storage tube into the centrifuge.
34. The pipeline for liquid detection according to claim 33, characterized in that A waiting tray for placing the liquid storage tube is provided at the top of the centrifuge housing; the second transfer mechanism can transfer the liquid storage tube to the waiting tray.
35. The pipeline for liquid detection according to claim 28, wherein, Further comprising: A cover storage area provided on the frame body for placing the cover.
36. The pipeline for liquid detection according to claim 29, wherein Further comprising: A pipette for sucking the liquid in the liquid storage tube at the storage position; the second transfer mechanism can drive the pipette to move in the XYZ directions.
37. The pipeline for liquid detection according to claim 36, wherein Further comprising: A nucleic acid extraction and detection unit, a carrier table provided on the frame body, a storage container detachably provided on the carrier table for temporarily storing liquid, and a third transfer mechanism for transferring the storage container into the nucleic acid extraction and detection unit for nucleic acid detection; The pipette can transfer the liquid in the liquid storage tube to the storage container through the second transfer mechanism.
38. The pipeline for liquid detection according to claim 37, characterized in that, The storage container has a protective cover; the clamping openers can remove and install the protective cover.
39. The pipeline for liquid detection according to claim 37, characterized in that, The stage can approach or move away from the nucleic acid extraction and detection unit through the second moving component.
40. The pipeline for liquid detection according to claim 37, wherein, It further includes: A stacking platform for stacking the storage containers and a lifting mechanism for driving the lifting and moving of the stacking platform; The third transfer mechanism can transfer the objects on the stacking platform.
41. The pipeline for liquid detection according to claim 37, characterized in that, The nucleic acid extraction and detection unit includes: A bracket provided on the frame; An amplification device provided on the bracket for temperature adjustment; An extraction device installed on the amplification device. The extraction device includes a test tube mounting component, a first driving member, and a magnetic attracting member. The test tube mounting component has a first mounting hole, the magnetic attracting member is provided on the inner wall of the first mounting hole, and the first driving member is installed on the bracket for driving the test tube mounting component to rotate, so as to drive the magnetic attracting member to rotate around the outer peripheral side of the test tube located in the test tube mounting component and perform nucleic acid extraction; the third transfer mechanism can transfer the storage container into the first mounting hole; A fluorescence detection device installed on the bracket for fluorescence detection of the test tube; and A driving device installed on the bracket, and the output end of the driving device is connected to the amplification device for driving the amplification device and the extraction device to rotate relative to the fluorescence detection device.
Citation Information
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