Automatic sample injector

Abstract

The invention discloses an automatic sample injector, and belongs to the technical field of sample injectors. The device comprises a driving device and a rotating disc, a transmission shaft is fixedly arranged at the output end of the driving device, a plurality of sets of placing openings are formed in the top of the rotating disc in a surrounding mode, and a bearing cylinder used for bearing a sample liquid bottle is rotationally arranged in each set of placing opening; a centrifugal driving mechanism used for driving all the bearing cylinders to rotate is rotationally arranged in the rotating disc, and a transmission assembly used for switching power transmission objects is arranged on the transmission shaft in a matched mode. During use, the driving device drives the transmission shaft to rotate so as to drive the transmission sleeve to rotate, the transmission sleeve drives the rotary guide sleeve to rotate through the transmission block, and the rotary guide sleeve drives the first driving wheel to rotate so as to drive the matched bearing cylinder to rotate, so that centrifugal operation of a sample liquid is realized; the possibility that two phases are partially mixed again due to interface disturbance caused by vibration or temperature fluctuation during standing of the centrifuged sample liquid is reduced.

Description

Technical Field

[0001] The present invention relates to the field of automatic samplers, and particularly to an automatic sampler. Background Art

[0002] An automatic sampler is an intelligent and automated sampling instrument, which is widely used in chromatographic experimental analysis. It can automatically complete a series of operations such as sample extraction, injection, and needle washing by presetting injection parameters without manual intervention.

[0003] In the water washing process of o-nitroaniline, it is necessary to frequently detect the chloride ion content in the oil phase (o-nitroaniline) and the residual amount of o-nitroaniline in the water phase (washing water) to evaluate the washing effect and yield. When in use, the automatic sampler can automatically inject the processed oil phase or water phase sample into the chromatograph to quantitatively analyze the chloride ion or o-nitroaniline concentration. It supports continuous sampling (such as hundreds of samples / batch), reduces manual operation errors, and ensures data consistency. Sometimes, the sample solution needs to be centrifuged after collection. The centrifugal force accelerates the complete stratification of the oil phase (o-nitroaniline) and the water phase, avoiding the mutual dissolution or entrainment of the residues of the two phases, and ensuring the accuracy of subsequent separate detection of chloride ions in the oil phase and o-nitroaniline in the water phase. At the same time, it can also separate the solid impurities (such as undissolved ammonium chloride, emulsification interface layer or filtration residues) that may be introduced in the process, preventing particles from clogging the pipelines or chromatographic columns of the automatic sampler and ensuring the long-term stable operation of the instrument. Thereby ensuring the sampling effect of the sampler and the accuracy of the chromatograph.

[0004] The centrifugal force treatment is generally achieved by a centrifuge. After centrifugation, the staff places the sample solution bottle on the automatic sampler. Since centrifugation and injection belong to different devices, the operation interface needs to be frequently started and stopped, and continuous batch processing cannot be achieved, which affects the detection speed. Secondly, the density difference between the oil phase (o-nitroaniline) and the water phase is small (the density of the oil phase is close to 1.2 g / cm 3 )). When standing after centrifugation, interface disturbance may be caused by slight vibration or temperature fluctuation (such as equipment vibration or environmental temperature difference), resulting in partial re-mixing of the two phases and affecting the accuracy of chromatograph detection. Summary of the Invention

[0005] The present invention provides an automatic sampler, which can solve the problem that the centrifuged sample solution in the prior art is vulnerable to environmental influence.

[0006] An automatic sampler includes a driving device and a rotating disk. A transmission shaft is fixedly arranged at the output end of the driving device. A plurality of placement openings are arranged around the top of the rotating disk. Inside each placement opening, a carrying cylinder for carrying a sample liquid bottle is rotatably arranged. An eccentric driving mechanism for driving all the carrying cylinders to rotate is rotatably arranged inside the rotating disk. A transmission component for switching the power transmission object is arranged on the transmission shaft, so as to selectively transmit power to the eccentric driving mechanism, or achieve the effect of the rotating disk and the eccentric driving mechanism as a whole.

[0007] As a further scheme of the present invention: the transmission component includes a transmission sleeve. The inner side of the transmission sleeve is slidably connected with the transmission shaft in the longitudinal direction. A transmission block for transmitting power to the eccentric driving mechanism and the rotating disk is fixedly arranged on the side surface of the transmission sleeve.

[0008] As a further scheme of the present invention: the eccentric driving mechanism includes a rotating guide sleeve rotatably arranged inside the rotating disk. A second transmission groove slidably matched with the transmission block is arranged inside the rotating guide sleeve. A connecting piece is fixedly arranged on the outer side of the rotating guide sleeve. The other end of the connecting piece is fixedly connected with a first driving wheel for driving all the carrying cylinders to rotate.

[0009] As a further scheme of the present invention: a gear is arranged on the outer side of the first driving wheel. A tooth groove meshing with the first driving wheel is arranged on the side surface of the carrying cylinder.

[0010] As a further scheme of the present invention: a connecting ring is fixedly arranged concentrically at the bottom of the rotating disk. The transmission shaft is coaxially arranged with the connecting ring. A first transmission groove slidably matched with the transmission block is arranged inside the connecting ring. A pushing mechanism for pushing the transmission sleeve to move up and down is arranged on the driving device.

[0011] As a further scheme of the present invention: the pushing mechanism includes a rotating sleeve rotatably arranged on the transmission sleeve. A connecting plate is fixedly arranged on the side surface of the rotating sleeve. A driving lifting component for pushing the connecting plate to move up and down is arranged between the connecting plate and the driving device.

[0012] As a further scheme of the present invention: a guide rod is fixedly arranged on the driving device. The connecting plate is slidably matched with the guide rod.

[0013] As a further scheme of the present invention: a locking block is fixedly arranged on the connecting plate. A positioning groove matched with the locking block is arranged at the bottom of the connecting ring.

[0014] As a further scheme of the present invention: a supporting component for supporting the rotating disk is arranged below the rotating disk.

[0015] As a further scheme of the present invention: the driving device is a servo motor.

[0016] Advantages of the present invention:

[0017] 1. When the present invention is in use, when the pushing mechanism pushes the transmission sleeve upward, the transmission block as a whole moves into the second transmission groove. The locking block will move upward under the action of the connecting plate, driving the locking block into the positioning groove, and locking the connecting ring through the locking block, thereby locking the rotating disk. When the connecting plate moves upward, it will drive the rotating sleeve upward. The rotating sleeve drives the transmission sleeve upward, and the transmission sleeve drives the transmission block to move so that it completely slides into the second transmission groove. The driving device drives the transmission shaft to rotate, thereby driving the transmission sleeve to rotate. The transmission sleeve drives the rotating guide sleeve to rotate through the transmission block. The rotating guide sleeve drives the first driving wheel to rotate, thereby driving the cooperating bearing cylinder to rotate, while the connecting ring remains stationary under the action of the locking block, thus preventing the rotating disk from rotating, realizing the centrifugation operation of the sample liquid, and reducing the possibility that the interface of the centrifuged sample liquid is disturbed due to long-term vibration or temperature fluctuation, resulting in partial remixing of the two phases.

[0018] 2. After the centrifugation operation is completed, the driving device drives the transmission sleeve and the rotating guide sleeve to reset. The pushing mechanism drives the connecting plate and the rotating sleeve downward, so that the transmission block moves into the first transmission groove and the second transmission groove. At the same time, the locking block leaves the positioning groove. The driving device drives the transmission sleeve to rotate through the transmission shaft. The transmission sleeve drives the rotating guide sleeve and the connecting ring to rotate, thereby driving the centrifugal driving mechanism and the rotating disk as a whole to rotate, thus facilitating the sampling device of the sampler to sample. Description of the Drawings

[0019] Figure 1 Schematic diagram of the overall structure of an automatic sampler provided by the present invention;

[0020] Figure 2 Schematic diagram of the driving device structure of an automatic sampler provided by the present invention;

[0021] Figure 3 Schematic diagram of the overall longitudinal section structure of an automatic sampler provided by the present invention;

[0022] Figure 4 Schematic diagram of the cross-section of the transmission sleeve of an automatic sampler provided by the present invention;

[0023] Figure 5 Schematic diagram of the centrifugal driving mechanism of an automatic sampler provided by the present invention.

[0024] Description of the reference numerals:

[0025] 1. Sampler sampling device; 2. Support assembly; 3. Rotating disk; 301. Placement port; 4. Driving device; 401. Transmission shaft; 5. Transmission sleeve; 501. Transmission block; 6. Connecting ring; 601. First transmission groove; 602. Positioning groove; 7. Carrying cylinder; 8. Centrifugal driving mechanism; 801. Rotating guide sleeve; 802. Second transmission groove; 803. Connecting piece; 804. First driving wheel; 9. Pushing mechanism; 901. Driving lifting assembly; 902. Connecting plate; 903. Rotating sleeve; 904. Guide rod; 10. Locking block. Detailed implementation manners

[0026] The following will describe in detail the specific implementation manners of the present invention, but it should be understood that the protection scope of the present invention is not limited by the specific implementation manners.

[0027] As Figures 1 to 5 shown, an automatic sampler provided by an embodiment of the present invention includes a driving device 4 and a rotating disk 3. A transmission shaft 401 is fixedly arranged at the output end of the driving device 4, and the driving device 4 is preferably a servo motor. A plurality of groups of placement ports 301 are arranged around the top of the rotating disk 3, and a carrying cylinder 7 for carrying a sample liquid bottle is rotatably arranged inside each group of placement ports 301. A centrifugal driving mechanism 8 for driving all the carrying cylinders 7 to rotate self is rotatably arranged inside the rotating disk 3. A transmission assembly for switching the power transmission object is arranged in cooperation on the transmission shaft 401, so as to selectively transmit power to the centrifugal driving mechanism 8, or the overall effect of the rotating disk 3 and the centrifugal driving mechanism 8. A support assembly 2 for supporting the rotating disk 3 is arranged below the rotating disk 3 to maintain the stability of the rotating disk 3 during rotation.

[0028] As Figure 5As shown, the transmission assembly includes a transmission sleeve 5, which is slidably connected longitudinally between the inner side of the transmission sleeve 5 and the transmission shaft 401. In this embodiment, the inner side of the transmission sleeve 5 and the outer side of the transmission shaft 401 are both provided with longitudinally extending and mutually cooperating patterns to ensure that the transmission shaft 401 can drive the transmission sleeve 5 to rotate. A transmission block 501 for transmitting power to the centrifugal drive mechanism 8 and the rotating disk 3 is fixedly provided on the side of the transmission sleeve 5. Among them, the centrifugal drive mechanism 8 includes a rotating guide sleeve 801 rotatably arranged inside the rotating disk 3. A second transmission groove 802 slidably engaged with the transmission block 501 is provided inside the rotating guide sleeve 801. The transmission block 501 drives the rotating guide sleeve 801 to rotate through the second transmission groove 802, thereby realizing the drive of the rotating guide sleeve 801. A connecting member 803 is fixedly provided on the outer side of the rotating guide sleeve 801, and the other end of the connecting member 803 is fixedly connected with a first driving wheel 804 for driving all the bearing cylinders 7 to rotate. A gear is provided on the outer side of the first driving wheel 804, and a tooth groove engaged with the first driving wheel 804 is provided on the side of the bearing cylinder 7. When the rotating guide sleeve 801 rotates, it can drive the first driving wheel 804 to rotate, and further drive the matching bearing cylinder 7 to rotate, driving the sample liquid bottle inside the bearing cylinder 7 to perform centrifugal motion.

[0029] When the transmission block 501 completely enters the second transmission groove 802 of the rotating guide sleeve 801, the locking block 10 is synchronously inserted into the positioning groove 602 of the connecting ring 6 to fix the rotating disk 3. Start the servo motor. At this time, the servo motor drives the transmission shaft 401 to rotate, the transmission shaft 401 drives the transmission sleeve 5 to rotate, the transmission sleeve 5 drives the transmission block 501 on one side to perform a circular motion, the transmission block 501 drives the rotating guide sleeve 801 to rotate through the second transmission groove 802, the rotating guide sleeve 801 drives the connecting member 803 to rotate, and further drives the first driving wheel 804 to rotate. The gear on the side of the first driving wheel 804 drives the bearing cylinder 7 to rotate. The bearing cylinder 7 rotates at a high speed around its own axis, and the substances in the sample liquid bottle are layered under the action of centrifugal force.

[0030] As Figure 3 , Figure 5 shown, multiple groups of placement openings 301 and bearing cylinders 7 are also arranged in a ring on the inner side of the top of the rotating disk 3. A second driving wheel is provided at the upper end of the rotating guide sleeve 801, which can be used to drive the above-mentioned bearing cylinders 7 to rotate.

[0031] A connecting ring 6 is fixedly disposed concentrically at the bottom of the rotating disk 3, and the transmission shaft 401 is coaxially disposed with the connecting ring 6. A first transmission groove 601 that is slidably matched with the transmission block 501 is provided on the inner side of the connecting ring 6. A driving mechanism 9 that drives the transmission sleeve 5 to move up and down is disposed on the driving device 4. If the driving mechanism 9 drives the transmission block 501 to move to the inside of the second transmission groove 802 and is separated from the first transmission groove 601, the driving of the rotating guide sleeve 801 can be realized. If the driving mechanism 9 drives the transmission block 501 to move to the inside of the first transmission groove 601 and the second transmission groove 802 (the positions of the first transmission groove 601 and the second transmission groove 802 correspond to each other, as shown in FIG. 1 , FIG. 1 ), the rotating guide sleeve 801 can be driven. Figure 5 As shown), the driving of the rotating guide sleeve 801 and the rotating disk 3 can be realized.

[0032] The pushing mechanism 9 includes a rotating sleeve 903 rotatably arranged on the transmission sleeve 5, a connecting plate 902 is fixedly arranged on the side of the rotating sleeve 903, and a driving lifting component 901 for pushing the connecting plate 902 to move up and down is arranged between the connecting plate 902 and the driving device 4. The driving lifting component 901 can be an electric telescopic rod, a pneumatic telescopic rod, or an electric guide rail, all of which fall within the protection scope of this patent. A guide rod 904 is fixedly arranged on the driving device 4, and the connecting plate 902 is slidably matched with the guide rod 904.

[0033] To prevent the rotating guide sleeve 801 from driving the rotating disk 3 to rotate when it rotates, a locking block 10 is fixedly arranged on the connecting plate 902, and a positioning groove 602 matching the locking block 10 is formed at the bottom of the connecting ring 6. When the pushing mechanism 9 pushes the transmission sleeve 5 upward, the whole transmission block 501 moves into the second transmission groove 802. The locking block 10 will move upward under the action of the connecting plate 902, driving the locking block 10 into the positioning groove 602, and locking the connecting ring 6 through the locking block 10, thereby locking the rotating disk 3. When the connecting plate 902 moves upward, it will drive the rotating sleeve 903 to move upward. The rotating sleeve 903 drives the transmission sleeve 5 to move upward, and the transmission sleeve 5 drives the transmission block 501 to move so that it completely slides into the second transmission groove 802. The driving device 4 drives the transmission shaft 401 to rotate, thereby driving the transmission sleeve 5 to rotate. The transmission sleeve 5 drives the rotating guide sleeve 801 to rotate through the transmission block 501. The rotating guide sleeve 801 drives the first driving wheel 804 to rotate, thereby driving the cooperating bearing cylinder 7 to rotate, while the connecting ring 6 remains stationary under the action of the locking block 10, thus preventing the rotating disk 3 from rotating. After the centrifugation operation is completed, the driving device 4 drives the transmission sleeve 5 and the rotating guide sleeve 801 to reset. The pushing mechanism 9 drives the connecting plate 902 and the rotating sleeve 903 to move downward, so that the transmission block 501 moves into the first transmission groove 601 and the second transmission groove 802, and at the same time the locking block 10 leaves the positioning groove 602. The driving device 4 drives the transmission sleeve 5 to rotate through the transmission shaft 401. The transmission sleeve 5 drives the rotating guide sleeve 801 and the connecting ring 6 to rotate, thereby driving the centrifugal driving mechanism 8 and the rotating disk 3 to rotate as a whole, thus facilitating the sampler sampling device 1 to sample.

[0034] This technology integrates the centrifugal drive and automatic sampling functions, significantly improving the overall efficiency of sample liquid processing. Compared with traditional manual operations, its closed-loop control system driven by a servo motor can achieve seamless connection between centrifugal separation and sampling, reducing interfacial contamination or data deviation caused by human intervention during sample transfer. For example, the residual error of oil-water phase separation in the o-nitroaniline water washing process can be reduced to less than 0.1 ppm. At the same time, through the intelligent switching of the transmission components, the device can quickly switch between the centrifugal mode and the rotating disk sampling mode, improving the processing efficiency of a single batch of samples, and can accurately control the centrifugal speed and standing time to avoid the residual of the emulsion layer or the re-precipitation of slightly soluble substances interfering with the detection results.

[0035] Working principle: Place the sample liquid bottle containing the sample liquid into the bearing cylinder 7 on the top of the rotating disk 3, and ensure that the bottle body is vertically fixed in the placement port 301.

[0036] Control the connecting plate 902 to move upward by driving the lifting component 901, driving the rotating sleeve 903 and the transmission sleeve 5 to move upward. When the transmission block 501 completely enters the second transmission groove 802 of the rotating guide sleeve 801, the locking block 10 is synchronously embedded in the positioning groove 602 of the connecting ring 6 to fix the rotating disk 3. The staff can manually touch the rotating disk 3 gently to confirm that it cannot rotate (the locking takes effect). Set the centrifugation parameters (such as a rotation speed of 2000 rpm and a time of 5 min), and start the servo motor. At this time, the servo motor drives the transmission shaft 401 to rotate, the transmission shaft 401 drives the transmission sleeve 5 to rotate, the transmission sleeve 5 drives the transmission block 501 on one side to perform a circular motion, the transmission block 501 drives the rotating guide sleeve 801 to rotate through the second transmission groove 802, the rotating guide sleeve 801 drives the connecting piece 803 to rotate, and further drives the first driving wheel 804 to rotate. The gear on the side of the first driving wheel 804 drives the sample carrier 7 to rotate. The sample carrier 7 rotates at a high speed around its own axis, and the substances in the sample vial are layered under the action of centrifugal force.

[0037] After centrifugation is completed, drive the transmission block 501 to correspond to the positions of the second transmission groove 802 and the first transmission groove 601, and the servo motor automatically stops. Pull down the connecting plate 902 by driving the lifting component 901 so that the transmission block 501 is located inside both the first transmission groove 601 and the second transmission groove 802 at the same time, and the locking block 10 disengages from the positioning groove 602. Set the rotation speed of the rotating disk 3 (such as 30 rpm), and drive the transmission shaft 401 to rotate. At this time, the servo motor drives the transmission shaft 401 to rotate, the transmission shaft 401 drives the transmission sleeve 5 to rotate, the transmission sleeve 5 drives the transmission block 501 to rotate, the transmission block 501 drives the connecting ring 6 to rotate through the first transmission groove 601, the connecting ring 6 drives the rotating disk 3, and the rotating guide sleeve 801 rotates synchronously with the connecting ring 6, driving the sample carrier 7 and the sample vial to revolve with the rotating disk 3.

[0038] When the target sample vial rotates to the sampling position, the sampler automatically extends into the sample carrier 7 to extract the specified phase (such as the supernatant) after layering. Precisely adjust the angle of the rotating disk 3 through the servo motor to ensure that the alignment error between the sampling needle and the sample vial is ≤ 0.5 mm.

[0039] After sampling, turn off the power of the driving device 4, reset the transmission sleeve 5 to the initial position, and complete the sampling operation.

[0040] The above only discloses several specific embodiments of the present invention. However, the embodiments of the present invention are not limited thereto, and any changes that can be conceived by those skilled in the art should fall within the protection scope of the present invention.

Claims

1. An automatic sampler, comprising a driving device (4) and a rotating disk (3), wherein a transmission shaft (401) is fixedly arranged at an output end of the driving device (4), and a plurality of groups of placement openings (301) are arranged around the top of the rotating disk (3), and it is characterized in that, Inside each of the placement openings (301), a carrier cylinder (7) for carrying a sample liquid bottle is rotatably provided. Inside the rotating disk (3), a centrifugal drive mechanism (8) for driving all the carrier cylinders (7) to rotate is rotatably provided. A transmission assembly for switching the power transmission object is arranged in cooperation with the transmission shaft (401), so as to selectively transmit power to the centrifugal drive mechanism (8), or achieve the effect of the rotating disk (3) and the centrifugal drive mechanism (8) as a whole.

2. The automatic sampler according to claim 1, wherein, The transmission assembly includes a transmission sleeve (5). The inner side of the transmission sleeve (5) is slidably connected to the transmission shaft (401) longitudinally. A transmission block (501) for transmitting power to the centrifugal drive mechanism (8) and the rotating disk (3) is fixedly provided on the side of the transmission sleeve (5).

3. An autosampler according to claim 2, wherein The centrifugal drive mechanism (8) includes a rotating guide sleeve (801) rotatably provided inside the rotating disk (3). A second transmission groove (802) slidably engaged with the transmission block (501) is formed inside the rotating guide sleeve (801). A connecting member (803) is fixedly provided on the outer side of the rotating guide sleeve (801). The other end of the connecting member (803) is fixedly connected to a first driving wheel (804) for driving all the carrier cylinders (7) to rotate.

4. The automatic sampler according to claim 3, characterized in that, A gear is provided on the outer side of the first driving wheel (804). A tooth groove engaged with the first driving wheel (804) is formed on the side of the carrier cylinder (7).

5. An autosampler according to claim 3, wherein, A connecting ring (6) is fixedly provided concentrically at the bottom of the rotating disk (3). The transmission shaft (401) is coaxially arranged with the connecting ring (6). A first transmission groove (601) slidably engaged with the transmission block (501) is formed inside the connecting ring (6). A pushing mechanism (9) for pushing the transmission sleeve (5) to move up and down is arranged on the driving device (4).

6. An automatic sampler according to claim 5, characterized in that, The pushing mechanism (9) includes a rotating sleeve (903) rotatably provided on the transmission sleeve (5). A connecting plate (902) is fixedly provided on the side of the rotating sleeve (903). A driving lifting assembly (901) for pushing the connecting plate (902) to move up and down is arranged between the connecting plate (902) and the driving device (4).

7. An autosampler according to claim 6, wherein A guide rod (904) is fixedly provided on the driving device (4). The connecting plate (902) is slidably engaged with the guide rod (904).

8. An autosampler according to claim 6, characterized in that, A locking block (10) is fixedly provided on the connecting plate (902). A positioning groove (602) matched with the locking block (10) is formed at the bottom of the connecting ring (6).

9. An automatic sampler according to claim 1, characterized in that, A support assembly (2) for supporting the rotating disk (3) is provided below the rotating disk (3).

10. An automatic sampler according to claim 1, characterized in that, The driving device (4) is a servo motor.

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