Micro-fluidic chip detection device

Abstract

The invention discloses a micro-fluidic chip detection device, and relates to the technical field of micro-fluidic chips, the micro-fluidic chip detection device comprises a micro-fluidic chip body, a puncturing assembly and a limiting assembly, the micro-fluidic chip body is provided with a capsule cavity for placing a diluent capsule, a push handle is slidably connected in the capsule cavity, and the puncturing assembly and the limiting assembly are respectively arranged in the push handle. The push handle is positioned in the micro-fluidic chip body through the elastic piece, the push handle is prevented from sliding randomly in the transportation and transfer process to squeeze and break the diluent bag, the outer end of the push rod just extends into the pressing groove of the push handle, the bending rod is bent by 90 degrees, the push rod is prevented from being pressed, and the reliability of the micro-fluidic chip is improved. Meanwhile, the puncturing piece retracts into the push handle under the elastic force effect of the spring, the puncturing piece is prevented from making contact with the diluent bag to puncture the diluent bag in advance, the elastic piece is positioned into the elastic limiting block through the extrusion piece, the push handle can slide in the bag cavity, and meanwhile the puncturing piece stretching out of the push handle is limited; and the diluent bag can be conveniently punctured by a subsequent puncture sheet.

Description

Technical Field

[0001] The present invention relates to the technical field of microfluidic chips, and particularly relates to a microfluidic chip detection device. Background Art

[0002] A microfluidic chip is a miniaturized technology platform. Its core principle is to achieve precise manipulation of liquids through microscale hydrodynamics, and it has characteristics such as high integration, low sample consumption, fast reaction, and high sensitivity. In the prior art, some microfluidic chip detection devices need to puncture a dilution liquid sac through a pushing puncturing mechanism during use, so that the dilution liquid in the dilution liquid sac can flow into the reaction chamber of the microfluidic chip body for corresponding detection experiments. However, the puncturing mechanism is packaged together with the dilution liquid sac, and it is easy for the dilution liquid sac to collide with the puncturing mechanism and the pushing component by itself during transportation and transfer, causing puncturing and allowing the dilution liquid to flow out in advance, thus affecting the subsequent detection effect. Summary of the Invention

[0003] The purpose of the present invention is to provide a microfluidic chip detection device to overcome the above-mentioned defects in the prior art.

[0004] A microfluidic chip detection device includes a microfluidic chip body. A sac cavity for placing a dilution liquid sac is provided on the microfluidic chip body. A push handle is slidably connected in the sac cavity, and a puncturing component and a limiting component are further included; The puncturing component is arranged in the push handle and punctures the dilution liquid sac when a puncturing piece extends out of the push handle; The limiting component is arranged in the push handle and is used for positioning the non-moved push handle and positioning the puncturing piece extending out of the push handle.

[0005] Preferably, the puncturing component further includes a guide rod, a support plate, a spring, and a push rod. The guide rod is arranged between the inner wall of the push handle and a fixed block in the push handle. The support plate is slidably connected to the guide rod through a slider on its lower side. The puncturing piece is arranged on the side of the support plate and extends out through a slot hole at the inner end of the push handle. The spring is sleeved on the guide rod and is used between the inner wall of the push handle and the slider. The push rod is slidably connected to the push handle and its inner end is connected to the support plate. The outer end of the push rod just extends into the pressure groove of the push handle.

[0006] Preferably, the limiting component includes an elastic piece, an extrusion piece, and a limiting block. The elastic piece is arranged in the push handle and its two ends respectively extend out through side holes on both sides of the push handle and are inserted into positioning grooves on the inner wall of the sac cavity. The extrusion piece is arranged on the side of the support plate. The limiting block is arranged on the inner wall of the push handle and is opposite to the extrusion piece. The elastic piece is located between the extrusion piece and the limiting block.

[0007] Preferably, the extrusion piece includes a vertical plate and a convex body. The convex body is connected to the support plate through the vertical plate, and the convex body is a cylindrical structure.

[0008] Preferably, the limiting block is made of an elastic material. A strip-shaped groove is provided at the end of the limiting block. The strip-shaped groove communicates with the limiting groove on the limiting block, and the limiting groove is a cylindrical structure.

[0009] Preferably, the limiting block is symmetrically provided with extrusion inclined surfaces on both sides of the strip-shaped groove.

[0010] Preferably, the support plate is in an inverted "L" shape structure.

[0011] Preferably, the outer end of the push rod is hinged with a bent rod through a pin shaft.

[0012] The beneficial effects achieved by the present invention are as follows: 1. In this application, the push handle is positioned in the microfluidic chip body through the elastic sheet, avoiding the random sliding of the push handle during transportation and transfer, which may cause extrusion and breakage of the dilution liquid sac. The outer end of the push rod just extends into the pressing groove of the push handle, and the bent rod is bent at 90°, avoiding the pressing of the push rod. At the same time, the puncturing sheet retracts into the push handle under the action of the spring elasticity, avoiding the contact between the puncturing sheet and the dilution liquid sac and preventing it from being punctured in advance.

[0013] 2. In this application, the elastic sheet is positioned in the elastic limiting block through the pressing member, enabling the push handle to slide in the sac cavity, and at the same time limiting the puncturing sheet extending out of the push handle, facilitating the subsequent puncturing of the dilution liquid sac by the puncturing sheet. Description of the Drawings

[0014] Figure 1 It is a schematic structural diagram of the whole of the present invention.

[0015] Figure 2 It is a schematic structural diagram of the interior of the present invention.

[0016] Figure 3 It is a top view of the interior of the push handle of the present invention.

[0017] Figure 4 It is a schematic structural diagram of the interior of the push handle of the present invention.

[0018] Figure 5 It is a schematic structural diagram of the puncturing assembly and the limiting assembly of the present invention.

[0019] Figure 6 It is Figure 5 a partial enlarged view of.

[0020] Figure 7 It is a schematic structural diagram of the limiting block of the present invention.

[0021] In the figure, 1 is the main body of the microfluidic chip; 11 is the cyst cavity; 2 is the push handle; 3 is the puncturing component; 31 is the puncturing piece; 32 is the guiding rod; 33 is the fixing block; 34 is the support plate; 35 is the sliding block; 36 is the spring; 37 is the push rod; 38 is the bent rod; 4 is the limiting component; 41 is the elastic sheet; 42 is the extrusion piece; 421 is the vertical plate; 422 is the convex body; 43 is the limiting block; 431 is the strip-shaped groove; 432 is the limiting groove; 433 is the extrusion inclined surface. Detailed implementation mode

[0022] The following is a more detailed description of the specific implementation mode of the present invention by describing the embodiments with reference to the accompanying drawings, so as to help those skilled in the art have a more complete, accurate and in-depth understanding of the concept and technical solution of the present invention.

[0023] As Figure 1-7 shown, the present invention provides a microfluidic chip detection device, including the main body 1 of the microfluidic chip. A cyst cavity 11 for placing a dilution solution cyst is provided on the main body 1 of the microfluidic chip. A push handle 2 is slidably connected in the cyst cavity 11. It is characterized in that: it further includes a puncturing component 3 and a limiting component 4; In addition, the puncturing component 3 is arranged in the push handle 2 and punctures the dilution solution cyst when the puncturing piece 31 on it extends out of the push handle 2. The puncturing component 3 further includes a guiding rod 32, a support plate 34, a spring 36 and a push rod 37. The guiding rod 32 is arranged between the inner wall of the push handle 2 and the fixing block 33 in the push handle 2. The support plate 34 is in an inverted "L" shape and is slidably connected to the guiding rod 32 through the sliding block 35 on its lower side. The puncturing piece 31 is arranged on the side of the support plate 34 and extends out through the slot hole at the inner end of the push handle 2. The spring 36 is sleeved on the guiding rod 32 and is used between the inner wall of the push handle 2 and the sliding block 35; The push rod 37 is slidably connected to the push handle 2 and its inner end is connected to the support plate 34. The outer end of the push rod 37 just extends into the pressure groove of the push handle 2. The outer end of the push rod 37 is hinged with a bent rod 38 through a pin shaft. After the bent rod 38 rotates 90°, it can press the push rod 37 to move, so that the puncturing piece 31 extends out of the push handle 2; In addition, the limiting component 4 is arranged in the push handle 2 and is used to position the unmoved push handle 2 and the puncturing piece 31 extending out of the push handle 2. The limiting component 4 includes an elastic piece 41, a pressing piece 42 and a limiting block 43. The elastic piece 41 is arranged in the push handle 2, and its two ends respectively extend out through the side holes on both sides of the push handle 2 and are inserted into the positioning grooves on the inner wall of the capsule cavity 11. The pressing piece 42 is arranged on the side surface of the support plate 34. The pressing piece 42 includes a vertical plate 421 and a convex body 422. The convex body 422 is connected to the support plate 34 through the vertical plate 421. The convex body 422 is of a cylindrical structure. The limiting block 43 is arranged on the inner wall of the push handle 2 and faces the pressing piece 42. The elastic piece 41 is located between the pressing piece 42 and the limiting block 43. The limiting block 43 is made of an elastic material. A strip-shaped groove 431 is arranged at the end of the limiting block 43, and the strip-shaped groove 431 communicates with the limiting groove 432 on the limiting block 43. Pressing inclined surfaces 433 are symmetrically arranged on both sides of the strip-shaped groove 431 of the limiting block 43, which facilitates the convex body 422 of the pressing piece 42 to drive the elastic piece 41 into the limiting groove 432 more easily for positioning. The limiting groove 432 is of a cylindrical structure.

[0024] Specific implementation manners and principles: When the microfluidic chip body 1 is not working, both ends of the elastic piece 41 extend out through the side holes on both sides of the push handle 2 and are inserted into the positioning grooves on the inner wall of the capsule cavity 11 to position the push handle 2 in the microfluidic chip body 1. At the same time, under the elastic force of the spring 36 on the guide rod 32, the puncturing piece 31 retracts into the push handle 2 to avoid the puncturing piece 31 contacting the diluent capsule and puncturing it in advance. When the microfluidic chip body 1 needs to work, an operator holds the push handle 2 with one hand, and rotates the bending rod 38 with the other hand by 90° to face the push rod 37. Then, the push rod 37 is pushed through the bending rod 38, so that the slider 35 on the support plate 34 moves along the guide rod 32, and the puncturing piece 31 gradually extends out of the push handle 2. During the movement of the support plate 34, the pressing piece 42 on the support plate 34 presses the elastic piece 41, so that the elastic piece 41 disengages from the positioning groove on the inner wall of the microfluidic chip body 1. The convex body 422 of the pressing piece 42 drives the elastic piece 41 to enter the limiting groove 432 through the strip-shaped groove 431 on the limiting block 43. Since the limiting block 43 is made of an elastic material, the limiting block 43 deforms to clamp and fix the pressing piece 42 and the elastic piece 41. At this time, the puncturing piece 31 has completed extending out of the push handle 2, and both ends of the elastic piece 41 are respectively located in the side holes on both sides of the push handle 2. Then, the push handle 2 is pushed to puncture the diluent capsule through the puncturing piece 31, so that the diluent in the diluent capsule flows into the reaction cavity of the microfluidic chip body 1 for corresponding detection experiments.

[0025] The embodiments of the present invention described above do not constitute a limitation on the protection scope of the present invention. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principle of the present invention shall be included within the protection scope of the claims of the present invention.

Claims

1. A microfluidic chip detection device, comprising a microfluidic chip body (1), wherein a cavity (11) for placing a dilution liquid sac is provided on the microfluidic chip body (1), and a push handle (2) is slidably connected in the cavity (11), characterized in that: It further includes a puncturing component (3) and a limiting component (4); The puncturing component (3) is arranged in the push handle (2) and punctures the diluent sac when the puncturing piece (31) on it extends out of the push handle (2); The limiting component (4) is arranged in the push handle (2) and is used for positioning the non - moved push handle (2) and positioning the puncturing piece (31) extending out of the push handle (2).

2. The microfluidic chip detection device according to claim 1, wherein: The puncturing component (3) further includes a guide rod (32), a support plate (34), a spring (36) and a push rod (37). The guide rod (32) is arranged between the inner wall of the push handle (2) and a fixed block (33) in the push handle (2). The support plate (34) is slidably connected to the guide rod (32) through a slider (35) on its lower side. The puncturing piece (31) is arranged on the side of the support plate (34) and extends out through a slot hole at the inner end of the push handle (2). The spring (36) is sleeved on the guide rod (32) and is between the inner wall of the push handle (2) and the slider (35). The push rod (37) is slidably connected to the push handle (2) and its inner end is connected to the support plate (34). The outer end of the push rod (37) just extends into the pressing groove of the push handle (2).

3. A microfluidic chip detection device according to claim 2, characterized in that: The limiting component (4) includes an elastic piece (41), a squeezing piece (42) and a limiting block (43). The elastic piece (41) is arranged in the push handle (2) and its two ends respectively extend out through side holes on both sides of the push handle (2) and are inserted into positioning grooves on the inner wall of the capsule cavity (11). The squeezing piece (42) is arranged on the side of the support plate (34). The limiting block (43) is arranged on the inner wall of the push handle (2) and faces the squeezing piece (42). The elastic piece (41) is located between the squeezing piece (42) and the limiting block (43).

4. A microfluidic chip detection device according to claim 3, characterized in that: The squeezing piece (42) includes a vertical plate (421) and a convex body (422). The convex body (422) is connected to the support plate (34) through the vertical plate (421). The convex body (422) is of a cylindrical structure.

5. A microfluidic chip detection device according to claim 3, characterized in that: The limiting block (43) is made of an elastic material. A strip - shaped groove (431) is provided at the end of the limiting block (43). The strip - shaped groove (431) communicates with a limiting groove (432) on the limiting block (43). The limiting groove (432) is of a cylindrical structure.

6. A microfluidic chip detection device according to claim 5, characterized in that: The limiting block (43) is symmetrically provided with squeezing inclined surfaces (433) on both sides of the strip - shaped groove (431).

7. A microfluidic chip detection device according to claim 2, characterized in that: The support plate (34) is of an inverted "L" - shaped structure.

8. A microfluidic chip detection device according to claim 2, characterized in that: The outer end of the push rod (37) is hinged with a bent rod (38) through a pin shaft.

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