Liquid preparation method in disposable liquid preparation scene, liquid preparation system, control equipment and storage medium

Abstract

The invention discloses a liquid preparation method in a disposable liquid preparation scene, a liquid preparation system, control equipment and a storage medium. The method comprises the steps that in any liquid injection stage, the expected liquid weight of the liquid injection stage and the actual liquid weight of the liquid injection stage are obtained; under the condition that the actual liquid weight meets a first threshold value condition corresponding to the expected liquid weight, the liquid outlet is controlled to inject liquid into the preparation bag based on a multi-period injection mode, and in any injection period, when the injection duration of the liquid outlet reaches the set duration of the injection period, the liquid outlet is controlled to be closed; and when the interval condition is met, the liquid outlet is controlled to be opened, the next injection period is carried out until the actual liquid weight of the preparation bag meets the second threshold value condition corresponding to the expected liquid weight, the liquid outlet is controlled to be closed, and the liquid injection stage is completed.

Description

Technical Field

[0001] The present invention relates to the field of biopharmaceutical technology, and in particular to a liquid preparation method, a liquid preparation system, a control device and a storage medium in a disposable liquid preparation scenario. Background Art

[0002] The biopharmaceutical industry combines modern biotechnology with the research, development, and production of various new drugs, as well as with the diagnosis, prevention, and treatment of diseases. It has become one of the seven national strategic emerging industries, possessing immense practical and economic significance.

[0003] Solution preparation equipment used in the biopharmaceutical industry is mainly divided into two types: stainless steel equipment and disposable systems. Compared with traditional stainless steel systems, disposable systems do not require equipment cleaning, disinfection, and sterilization, eliminating the consumption of consumables such as cleaning agents and disinfectants. They do not require CIP (online cleaning) or SIP (online sterilization), eliminating the consumption of a large amount of energy. At the same time, disposable products do not require preliminary preparation processes, which has the advantages of saving time and labor.

[0004] In the process of realizing the present invention, it was found that there are at least the following technical problems in the prior art: the volume of solution prepared by the disposable liquid preparation system in a single time is not large, and if the solution volume requirement is large, multiple preparations are required; at the same time, the disposable liquid preparation process can only be manually connected and controlled by the operator, the degree of automation control is low, and the production efficiency is relatively low. Summary of the Invention

[0005] The present invention provides a liquid dispensing method, a liquid dispensing system, a control device and a storage medium in a disposable liquid dispensing scenario, thereby realizing automated control of the disposable liquid dispensing scenario.

[0006] According to one aspect of the present invention, a liquid dispensing method in a disposable liquid dispensing scenario is provided, wherein a disposable dispensing bag is provided in a liquid dispensing container, a liquid outlet of a liquid dispensing system injects liquid into the dispensing bag, and a weighing device in the liquid dispensing system is used to collect the weight of the liquid in the dispensing bag;

[0007] The method comprises:

[0008] In any liquid injection stage, obtaining the expected liquid weight of the liquid injection stage and the actual liquid weight of the liquid injection stage;

[0009] When the actual liquid weight satisfies the first threshold condition corresponding to the desired liquid weight, control the liquid outlet to inject liquid into the preparation bag based on a multi-period injection mode: in any injection period, when the injection duration of the liquid outlet reaches the set duration of the injection period, control the liquid outlet to close; when the interval condition is satisfied, control the liquid outlet to open and proceed to the next injection period until the actual liquid weight of the preparation bag satisfies the second threshold condition corresponding to the desired liquid weight, then control the liquid outlet to close and complete the liquid injection stage.

[0010] Optionally, the liquid outlet is configured with a control switch;

[0011] The method further includes: when the injection duration of the liquid outlet reaches the set duration of the injection period, generate a closing signal, send the closing signal to the control switch, and control the control switch to close; when the interval condition is satisfied, generate a start signal, send the start signal to the control switch, and control the control switch to open.

[0012] Optionally, the set durations corresponding to different injection periods are the same.

[0013] Optionally, the set durations corresponding to different injection periods are the same or different, and the set duration corresponding to a later injection period is less than or equal to the set duration corresponding to an earlier injection period.

[0014] Optionally, the set duration corresponding to each injection period is determined based on a preset ratio of the desired liquid weight and the flow rate of the liquid outlet.

[0015] Optionally, the interval condition includes one or more of the following: the closing duration of the liquid outlet satisfies a preset interval duration; after the liquid outlet closes, the actual liquid weight of the preparation bag reaches a stable state.

[0016] Optionally, the method further includes: in any of the liquid injection stages, read the operator information and perform permission verification on the operator information; when the permission verification of the operator information is successful, in response to the operator's injection trigger operation, control the liquid outlet to inject liquid into the preparation bag, and record and store the operation information corresponding to the liquid injection stage, where the operation information includes one or more of the liquid preparation task information, operator information, time information, operation type, and liquid preparation process information.

[0017] Optionally, a control panel is provided on the control device of the liquid preparation system; a start button is provided on the control panel, and the injection trigger operation is a trigger operation on the start button; an interaction interface is also configured on the control panel;

[0018] The method further includes: obtaining, through the interaction interface, the desired liquid weight of each of the liquid injection phases; and displaying, on the interaction interface, the actual liquid weight of the liquid injection phase.

[0019] Optionally, the liquid injection phase includes an initial injection phase and a constant volume injection phase.

[0020] According to another aspect of the present invention, there is provided a liquid preparation system, including: a control device, a liquid preparation container, and a liquid outlet. The liquid preparation container is configured with a weighing device, and a disposable preparation bag is provided in the liquid preparation container;

[0021] The control device is respectively communicatively connected to the weighing device of the liquid preparation container and the control switch of the liquid outlet;

[0022] The control device controls the liquid outlet to inject liquid into the preparation bag in any liquid injection phase, and receives the actual liquid weight collected by the weighing device;

[0023] When the actual liquid weight satisfies the first threshold condition corresponding to the desired liquid weight of the liquid injection phase, the control device controls the liquid outlet to inject liquid into the preparation bag based on a multi-period injection mode: in any injection period, when the injection duration of the liquid outlet reaches the set duration of the injection period, the control device controls the liquid outlet to close; when the interval condition is satisfied, the control device controls the liquid outlet to open for the next injection period until the actual liquid weight of the preparation bag satisfies the second threshold condition corresponding to the desired liquid weight, and then the control device controls the liquid outlet to close, completing the liquid injection phase.

[0024] According to another aspect of the present invention, there is provided a control device, which includes:

[0025] At least one processor; and

[0026] A memory communicatively connected to the at least one processor; wherein,

[0027] The memory stores a computer program executable by the at least one processor, and when the computer program is executed by the at least one processor, the at least one processor can execute the liquid preparation method in the disposable liquid preparation scenario of any embodiment of the present invention.

[0028] According to another aspect of the present invention, there is provided a computer-readable storage medium, which stores computer instructions for causing a processor to execute the liquid preparation method in the disposable liquid preparation scenario of any embodiment of the present invention when executed.

[0029] In the technical solution of the embodiment of the present invention, in a disposable liquid preparation scenario, the liquid outlet is controlled to inject liquid into a disposable preparation bag, and the weighing device is used to collect the actual liquid weight of the liquid in the preparation bag in real time. When the actual liquid weight meets the first threshold condition corresponding to the expected liquid weight, the liquid outlet is controlled to inject liquid into the preparation bag based on a multi-period injection mode. Based on the multi-period injection mode, the liquid is injected into the preparation bag in multiple intermittent injection periods, reducing the interference of the impact force of the liquid injection process on the actual liquid weight in the preparation bag, improving the accuracy of the actual liquid weight, and further improving the liquid preparation accuracy.

[0030] It should be understood that the content described in this part is not intended to identify the key or important features of the embodiments of the present invention, nor is it used to limit the scope of the present invention. Other features of the present invention will become easily understood through the following description. Brief Description of the Drawings

[0031] In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the following will briefly introduce the drawings required for the description of the embodiments. Obviously, the drawings in the following description are only some embodiments of the present invention. For those of ordinary skill in the art, without creative efforts, other drawings can be obtained based on these drawings.

[0032] Figure 1 It is a flowchart of the liquid preparation method in the disposable liquid preparation scenario provided in the first embodiment of the present invention;

[0033] Figure 2 It is a flowchart of the liquid preparation method in the disposable liquid preparation scenario provided in the second embodiment of the present invention;

[0034] Figure 3 It is a schematic structural diagram of a liquid preparation system provided in the third embodiment of the present invention;

[0035] Figure 4 It is a schematic structural diagram of a control device provided in the fourth embodiment of the present invention. Detailed Embodiments

[0036] In order to enable those skilled in the art to better understand the solution of the present invention, the following will clearly and completely describe the technical solutions in the embodiments of the present invention with reference to the drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present invention.

[0037] It should be noted that the terms "first", "second", etc. in the description, claims and above-mentioned drawings of the present invention are used to distinguish similar objects, and do not necessarily have to be used to describe a specific order or sequence. It should be understood that the data used in this way can be interchanged under appropriate circumstances, so that the embodiments of the present invention described here can be implemented in an order other than those illustrated or described here. In addition, the terms "comprising" and "having" and any variations thereof are intended to cover non-exclusive inclusion. For example, a process, method, system, product or device comprising a series of steps or units does not necessarily have to be limited to those steps or units clearly listed, but may include other steps or units not clearly listed or inherent to these processes, methods, products or devices.

[0038] Embodiment 1

[0039] The disposable liquid preparation scenario can be understood as a scenario where liquid preparation is achieved through a disposable preparation bag. The liquid preparation system includes a liquid preparation container, which may include but is not limited to a mixing tank. By arranging a disposable preparation bag in the liquid preparation container, liquid preparation is realized in the disposable preparation bag. The disposable preparation bag can be made of a flexible material, such as a soft bag made of polyethylene. The disposable preparation bag can be connected through a head-shaped silicone tube or a thermoplastic tube, which occupies a small area and saves clean space and energy.

[0040] During the liquid preparation process, it may include at least one liquid injection stage. In each liquid injection stage, the liquid injected into the preparation bag may include but is not limited to water, and the type of liquid injected can be determined according to the liquid preparation requirements. Optionally, the liquid injection stage includes an initial injection stage and a volume-fixing injection stage. Exemplarily, the liquid preparation process may include an initial injection stage, a feeding stage and a volume-fixing injection stage. Among them, in the initial injection stage, liquid is injected into the preparation bag so that the weight of the liquid in the preparation bag reaches a first desired weight; in the feeding stage, the materials required for liquid preparation are put into the preparation bag. Specifically, different materials can be put in batches and stirred; in the volume-fixing injection stage, liquid is injected into the preparation bag so that the weight of the liquid in the preparation bag reaches a second weight.

[0041] A weighing device is arranged in the liquid preparation system. The weighing device can be used to weigh the weight of the liquid in the preparation bag. Among them, the weighing device is arranged at the bottom of the liquid preparation container, or the weighing device can be integrated in the liquid preparation container, and the weight of the liquid in the liquid preparation container can be realized. The setting method of the weighing device is not limited here. The weighing device can be communicatively connected to the control device in the liquid preparation container, and can collect the weight of the liquid in the preparation bag in real time and transmit the weight of the liquid in the preparation bag to the control device in real time.

[0042] It should be noted that in the field of biopharmaceuticals, high precision is required for liquid preparation, and the error range between the weight of the injected liquid and the expected liquid weight is small in each liquid injection stage. Currently, manual control is required for liquid preparation, resulting in problems such as low production efficiency and high labor costs. In view of the above problems, the embodiments of the present invention provide a liquid preparation method applicable to a disposable liquid preparation scenario. Refer to Figure 1 , Figure 1 which is a flowchart of the liquid preparation method in a disposable liquid preparation scenario provided by Embodiment 1 of the present invention. This embodiment is applicable to automatically injecting liquid into a disposable preparation bag in a disposable liquid preparation scenario and providing automatic control of the liquid injection process. This method can be executed by a control device in the liquid preparation system, and the control device in the liquid preparation system can be implemented in the form of hardware and / or software. The control device in the liquid preparation system can include, but is not limited to, electronic devices such as mobile terminals and control cabinets.

[0043] As Figure 1 shown, the method includes:

[0044] S110. In any liquid injection stage, obtain the expected liquid weight of the liquid injection stage and the actual liquid weight of the liquid injection stage.

[0045] S120. When the actual liquid weight meets the first threshold condition corresponding to the expected liquid weight, control the liquid outlet to inject liquid into the preparation bag based on a multi-period injection mode.

[0046] In this embodiment, the liquid preparation system includes a control device, and the control device controls the opening or closing of the liquid outlet to achieve controlling the liquid outlet to inject liquid into the preparation bag or stop injecting liquid.

[0047] Optionally, the control device pre-obtains the expected liquid weight of each liquid injection stage, and the expected liquid weight of each liquid injection stage can be input by an operator through an input operation. Exemplarily, the control device in the liquid preparation system can be a mobile terminal, such as, but not limited to, a mobile phone, a tablet computer, and a PC. The mobile terminal is configured with a display screen, and the display screen can be used to display an interaction interface, and the expected liquid weight corresponding to each liquid injection stage can be collected through the interaction interface. Exemplarily, the control device in the liquid preparation system can be a control cabinet, and a control panel is provided on the control cabinet. The control panel can be configured with an interaction interface, and the expected liquid weight of each liquid injection stage can be obtained through the interaction interface.

[0048] The desired liquid weight corresponding to each liquid injection stage can be set according to the configuration requirements of the liquid preparation task. Among them, the desired liquid weight corresponding to the constant-volume injection stage can be the target liquid weight of the liquid preparation task, and the desired liquid weight corresponding to the initial injection stage can be a preset proportional value of the target liquid weight. This preset proportional value is not limited here.

[0049] In any liquid injection stage, in response to the injection trigger operation of the operator, the control device controls the liquid outlet to inject liquid into the preparation bag. When the control device is a control cabinet, a control panel is provided on the control device, and a start button is provided on the control panel. Correspondingly, the injection trigger operation is the trigger operation on the start button. When the control device is a mobile terminal, a start control is included in the interaction interface displayed on the display screen of the mobile terminal. Correspondingly, the injection trigger operation is the trigger operation on the start control.

[0050] Optionally, the liquid outlet is configured with a control switch; the control device is wirelessly or wiredly connected to the control switch to enable the transmission of control signals. In response to the injection trigger operation of the operator, the control device generates a start signal and sends the start signal to the control switch to control the control switch to turn on, so as to control the liquid outlet to inject liquid into the preparation bag.

[0051] During the liquid injection process in any liquid injection stage, the liquid weight of the preparation bag is collected in real time through a weighing device, that is, the actual liquid weight in the liquid injection stage. The weighing device is communicatively connected to the control device and transmits the actual liquid weight to the control device.

[0052] The control device displays the actual liquid weight of the liquid injection stage in the interaction interface, and compares the actual liquid weight of the liquid injection stage with the desired liquid weight to determine whether the actual liquid weight of the liquid injection stage reaches the desired liquid weight, so as to achieve precise control of the actual liquid weight in the liquid injection stage and further improve the liquid preparation accuracy.

[0053] Optionally, any liquid injection stage includes a continuous injection mode and a multi-period injection mode. Among them, the continuous injection mode can be understood as a mode in which the liquid outlet continuously injects liquid into the preparation bag; the multi-period injection mode can be understood as a mode in which liquid is intermittently injected into the preparation bag through multiple injection periods with time intervals. When the actual liquid weight does not meet the first threshold condition corresponding to the desired liquid weight, the continuous injection mode is adopted. When the actual liquid weight meets the first threshold condition corresponding to the desired liquid weight, the multi-period injection mode is adopted.

[0054] The first threshold condition corresponding to the expected liquid weight may be a liquid weight threshold determined based on the expected liquid weight and the first ratio value. For example, the liquid weight threshold may be a value obtained by multiplying the expected liquid weight by the first ratio value. For example, the expected liquid weight in a certain liquid injection stage is 2000 kg, and the first ratio value is 80%. Accordingly, the first threshold condition corresponding to the expected liquid weight may be 1600 kg. In the liquid injection stage, based on the continuous injection mode, the liquid outlet is controlled to continuously inject liquid into the preparation bag, and the actual liquid weight of the preparation bag is obtained in real time. When the actual liquid weight of the preparation bag reaches 1600 kg, it is determined that the actual liquid weight meets the first threshold condition corresponding to the expected liquid weight. Among them, the first threshold condition corresponding to the expected liquid weight may be preset, and the value of the first ratio value is not limited.

[0055] The first threshold condition corresponding to the expected liquid weight is used as the switching condition of the injection mode. When the first threshold condition corresponding to the expected liquid weight is met, the continuous injection mode is switched to the multi-period injection mode, and the liquid outlet is controlled to inject liquid into the preparation bag through the multi-period injection mode until the liquid injection in this liquid injection stage is completed.

[0056] It can be understood that the actual liquid weight meeting the first threshold condition corresponding to the expected liquid weight indicates that the actual liquid weight is close to the expected liquid weight. In order to avoid the situation that the actual liquid weight of the liquid in the preparation bag exceeds the expected liquid weight, the liquid is injected into the preparation bag in segments through the multi-period injection mode to improve the liquid preparation accuracy.

[0057] Optionally, when the actual liquid weight meets the first threshold condition corresponding to the expected liquid weight, the liquid outlet is controlled to close, and when the interval condition is met, the liquid outlet is controlled to open, entering the first injection period, and the liquid outlet injects liquid into the preparation bag. After the end of the first injection period, the liquid outlet is controlled to close, and when the interval condition is met, the liquid outlet is controlled to open, entering the second injection period, and so on until the liquid injection stage is completed.

[0058] It should be noted that during the process of the liquid outlet injecting liquid into the preparation bag, the liquid has a certain impact on the preparation bag, affecting the accuracy of the actual liquid weight of the preparation bag collected by the weighing device. By adopting the multi-period injection mode, there is an interruption time interval between adjacent injection periods, so that the liquid in the preparation bag gradually reaches a stable state during the interruption time interval, so as to eliminate the impact of the impact of the liquid injection process on the actual liquid weight and improve the accuracy of the actual liquid weight.

[0059] In the multi-period injection mode, multiple injection periods can be included. Optionally, in any injection period, when the injection duration at the liquid outlet reaches the set duration of the injection period, control the liquid outlet to close; when the interval condition is met, control the liquid outlet to open to start the next injection period until the actual liquid weight of the preparation bag meets the second threshold condition corresponding to the desired liquid weight, then control the liquid outlet to close to complete the liquid injection stage.

[0060] The control device pre-sets the start condition and end condition for each injection period. When the start condition of the injection period is met, control the liquid outlet to open; when the end condition of the injection period is met, control the liquid outlet to close. Optionally, a control switch is provided at the liquid outlet. When the start condition of the injection period is met, the control device generates a start signal and sends the start signal to the control switch to control the control switch to open, thereby controlling the liquid outlet to open. When the end condition of the injection period is met, the control device generates a close signal and sends the close signal to the control switch to control the control switch to close, thereby controlling the liquid outlet to close.

[0061] Among them, the start condition can include meeting the interval condition, and the end condition can include, for example, the set duration corresponding to the period. Correspondingly, when the injection duration at the liquid outlet reaches the set duration of the injection period, generate a close signal, send the close signal to the control switch, and control the control switch to close to control the liquid outlet to close; when the interval condition is met, generate a start signal, send the start signal to the control switch, and control the control switch to open to control the liquid outlet to open.

[0062] Optionally, the set durations corresponding to different injection periods are the same; the set duration corresponding to each injection period can be pre-set. For example, different set durations are set according to different desired liquid weights. When the desired liquid weight is 2000 kg, the set duration corresponding to each injection period can be t; when the desired liquid weight is 1000 kg, the set duration corresponding to each injection period can be t / 2. The set durations corresponding to multiple injection periods can meet the precise injection of the liquid corresponding to this liquid injection stage. Optionally, the total duration corresponding to multiple injection periods can be determined based on the total liquid weight corresponding to multiple periods and the liquid flow rate, and the set duration corresponding to each injection period can be determined based on the quotient of the total duration and the number of injection periods. Here, the number of injection periods can be determined according to the accuracy requirement.

[0063] Correspondingly, when the actual liquid weight meets the first threshold condition corresponding to the desired liquid weight, determine the number of injection periods and the set duration of the injection period based on the desired liquid weight.

[0064] Optionally, the set durations corresponding to different injection periods are the same or different. For example, multiple set durations for injection periods corresponding to different desired liquid weights are preset. The set durations for multiple injection periods corresponding to different desired liquid weights can be set in a configuration file. For example, they can be stored in the form of key-value pairs, where the key can be the desired liquid weight and the value can be the set durations for multiple injection periods.

[0065] Optionally, the set duration corresponding to the subsequent injection period is less than or equal to the set duration corresponding to the previous injection period. Exemplarily, in a multi-period injection mode for a certain liquid injection stage, there are 5 injection periods, and the set durations corresponding to the 5 injection periods can be 1 minute, 1 minute, 30 seconds, 20 seconds, and 10 seconds in sequence.

[0066] Optionally, the set duration corresponding to each injection period is determined based on a preset ratio of the desired liquid weight and the flow rate of the liquid outlet. Each injection period controls the liquid outlet to inject a liquid weight that is a preset ratio of the desired liquid weight into the preparation bag. For example, it can be 1%. The preset ratios of the liquid weights injected into the preparation bag by different injection periods to the desired liquid weight can be the same or different. The set duration corresponding to each injection period is determined based on the liquid weight injected into the preparation bag during each injection period and the flow rate of the liquid outlet, that is, during each injection period, the set duration corresponding to each injection period is determined by the quotient of the preset ratio of the desired liquid weight and the flow rate of the liquid outlet.

[0067] By setting multiple injection periods and the set duration of each injection period, segmented liquid injection through multiple injection periods can be achieved, improving the liquid injection accuracy and avoiding the situation of exceeding the desired liquid quantity.

[0068] Based on the above embodiments, an interval condition is set between different injection periods. When the interval condition is met, a new injection period is carried out, and this new injection period can be any one of the multiple injection periods.

[0069] Optionally, the interval condition can include that the closing duration of the liquid outlet meets a preset interval duration. In the case where the actual liquid weight meets the first threshold condition corresponding to the desired liquid weight, or, after the previous injection period is completed, the liquid outlet is controlled to close and the timing is started. The closing duration of the liquid outlet is determined. When the closing duration of the liquid outlet meets the preset interval duration, it is determined that the interval condition is met. By setting the preset interval duration, within this interval duration, the liquid outlet is closed, so that the fluctuation of the liquid in the preparation bag gradually decreases, and further the fluctuation of the actual liquid weight collected by the weighing device gradually decreases and tends to be stable, improving the accuracy of the actual liquid weight collection.

[0070] The preset interval duration can be positively correlated with the flow rate of the liquid outlet. The greater the flow rate of the liquid outlet, the greater the impact force of the liquid injection process on the liquid in the preparation bag, the greater the fluctuation of the liquid in the preparation bag, and correspondingly, the greater the fluctuation of the actual liquid weight collected by the weighing device, and the longer the duration required for the liquid fluctuation to return to a stable state, that is, the greater the preset interval duration.

[0071] Optionally, the interval condition may include that after the liquid outlet is closed, the actual liquid weight of the preparation bag reaches a stable state. The stable state of the actual liquid weight can be understood as that the fluctuation value of the actual liquid weight is less than the preset fluctuation threshold. When the actual liquid weight meets the first threshold condition corresponding to the expected liquid weight, or, when the previous injection period is completed, the fluctuation value of the actual liquid weight is determined. This fluctuation value can be understood as the difference between the actual liquid weights at adjacent moments, or the difference between the maximum actual liquid weight and the minimum actual liquid weight within a preset time period.

[0072] When the fluctuation value of the actual liquid weight is less than the preset fluctuation threshold, it indicates that the liquid fluctuation in the preparation bag decreases and tends to be stable, further indicating that the impact force of the liquid injection process on the liquid in the preparation bag decreases, and at this time, the accuracy of the actual liquid weight collected is high.

[0073] Based on the above embodiments, the actual liquid weight in the liquid injection stage is obtained in real time. When the actual liquid weight meets the second threshold condition corresponding to the expected liquid weight, it indicates that the actual liquid weight reaches the liquid weight required for this liquid injection stage, and the liquid outlet is controlled to close to complete the liquid injection stage. The second threshold condition corresponding to the expected liquid weight can be the liquid preparation accuracy range corresponding to this liquid injection stage. For example, it can be the weight range between the minimum proportional value corresponding to the expected liquid weight and the maximum proportional value corresponding to the expected liquid weight. The minimum proportional value can be 99.5%, and the maximum proportional value can be 100.5%. The minimum proportional value and the maximum proportional value here can be determined according to the liquid preparation accuracy. When the actual liquid weight is within the weight range between the minimum proportional value corresponding to the expected liquid weight and the maximum proportional value corresponding to the expected liquid weight, the liquid outlet is controlled to close to complete the liquid injection stage.

[0074] The technical solution of this embodiment, in a disposable liquid preparation scenario, controls the liquid outlet to inject liquid into a disposable preparation bag, and the weighing device is used to collect the actual liquid weight of the liquid in the preparation bag in real time. When the actual liquid weight meets the first threshold condition corresponding to the expected liquid weight, the liquid outlet is controlled to inject liquid into the preparation bag based on the multi-period injection mode. Based on the multi-period injection mode, the liquid is injected into the preparation bag in multiple discontinuous injection periods, reducing the interference of the impact force of the liquid injection process on the liquid in the preparation bag on the actual liquid weight, improving the accuracy of the actual liquid weight, and further improving the liquid preparation accuracy.

[0075] Example 2

[0076] Figure 2 is a flowchart of the liquid preparation method in the disposable liquid preparation scenario provided by the second embodiment of the present invention. On the basis of the above embodiment, the liquid preparation method is optimized to record data during the liquid preparation process, form a database that can be traced, queried, and analyzed, and realize the digital management of the liquid preparation process. As Figure 2 shown, the method includes:

[0077] S210. In any of the liquid injection stages, read the operator information and perform permission verification on the operator information.

[0078] S220. When the permission verification of the operator information is successful, in response to the injection trigger operation of the operator, control the liquid outlet to inject liquid into the preparation bag.

[0079] S230. Obtain the expected liquid weight in the liquid injection stage and the actual liquid weight in the liquid injection stage; when the actual liquid weight meets the first threshold condition corresponding to the expected liquid weight, control the liquid outlet to inject liquid into the preparation bag based on the multi-stage injection mode.

[0080] S240. Record and store the operation information corresponding to the liquid injection stage, where the operation information includes one or more of the liquid preparation task information, operator information, time information, operation type, and liquid preparation process information.

[0081] In this embodiment, the operator information can be information that uniquely represents the operator. For example, it can be to read the identification card worn by the operator to obtain the operator information. For example, it can be through the biometric information of the operator to identify and obtain the operator information.

[0082] The permission information of different operators is pre-set in the control device, and the permission information of different operators can be different. When the operator information is obtained, the operator information is subjected to permission verification. If the verification is successful, it indicates that the operator has the operation permission and can control the liquid outlet to inject liquid into the preparation bag through the injection trigger operation. By setting permissions for different operators, the safety of the liquid preparation operation is improved.

[0083] Among them, a start button is set on the control panel of the control device, and the injection trigger operation is the trigger operation on the start button. For each liquid injection stage, it is started separately through the injection trigger operation of the operator.

[0084] While injecting liquid during the liquid injection stage, record and store the operation information corresponding to the liquid injection stage, where the operation information includes dispensing task information, operator information, time information, and dispensing process information. The dispensing task information may include, but is not limited to, batch information of the dispensing task, dispensing type, etc. The operator information may include, but is not limited to, the identifier of the operator. The time information may include the timestamp of the injection trigger operation, or include the start timestamp and end timestamp of the liquid injection stage. The operation type may include, but is not limited to, start injection, stop injection, etc. The dispensing process information can be understood as the information generated during the liquid injection process in the liquid injection stage, such as the actual liquid weight and the desired liquid weight, etc.

[0085] For each liquid injection stage in the dispensing process, for each control operation in the liquid injection stage, generate corresponding operation information respectively. The control operation includes, but is not limited to, information input operation, injection trigger operation, pause operation, etc. Among them, the information input operation can be used to input one or more pieces of dispensing information such as the desired liquid information, liquid temperature, etc. for each liquid injection stage.

[0086] Optionally, in the case of power failure, store one or more pieces of dispensing information such as the input desired liquid information, liquid temperature, etc., and close the liquid outlet. In the case of power restoration, corresponding to the trigger operation of the start button, continue the liquid injection in the liquid injection stage.

[0087] The technical solution of this embodiment, by generating and storing one or more pieces of operation information including dispensing task information, operator information, time information, operation type, and dispensing process information during the liquid injection process of each liquid injection stage, can form a database for storing the above operation information. Through this database, the traceability, queryability, and analyzability of the operation information during the dispensing process can be realized, and the digital management of the information during the dispensing process can be realized.

[0088] Embodiment III

[0089] Figure 3 It is a schematic structural diagram of a dispensing system provided by Embodiment III of the present invention. As Figure 3 shown, the device includes: a control device 310, a dispensing container 320, and a liquid outlet 330. The dispensing container is configured with a weighing device 321, and a disposable preparation bag is arranged in the dispensing container;

[0090] The control device 310 is respectively connected to the weighing device 321 of the dispensing container 320 and the control switch 331 of the liquid outlet 330; Optionally, the above connection can be a wired connection, which is beneficial to improving the data transmission efficiency.

[0091] The control device 310 controls the liquid outlet 330 to inject liquid into the preparation bag during any liquid injection stage, and receives the actual liquid weight collected by the weighing device 321;

[0092] When the actual liquid weight meets the first threshold condition corresponding to the expected liquid weight in the liquid injection stage, the liquid outlet 330 is controlled to inject liquid into the preparation bag based on the multi-period injection mode: in any injection period, when the injection duration of the liquid outlet 330 reaches the set duration of the injection period, the liquid outlet 330 is controlled to close; when the interval condition is met, the liquid outlet 330 is controlled to open for the next injection period until the actual liquid weight of the preparation bag meets the second threshold condition corresponding to the expected liquid weight, and then the liquid outlet 330 is controlled to close to complete the liquid injection stage.

[0093] Optionally, an interaction interface is configured on the control device 310;

[0094] The interaction interface is used to obtain the expected liquid weight of each liquid injection stage; and display the actual liquid weight of the liquid injection stage on the interaction interface;

[0095] Optionally, a control switch 331 is configured on the liquid outlet 330;

[0096] When the injection duration of the liquid outlet 330 reaches the set duration of the injection period, the control device 310 generates a closing signal, sends the closing signal to the control switch 331, and controls the control switch 331 to close to control the liquid outlet 330 to stop liquid injection;

[0097] When the interval condition is met, the control device 310 generates a start signal, sends the start signal to the control switch 331, and controls the control switch 331 to open to control the liquid outlet 330 to inject liquid into the preparation bag.

[0098] Optionally, the control device 310 is also used to read the operator information during any liquid injection stage and perform permission verification on the operator information; when the permission verification of the operator information is successful, in response to the injection trigger operation of the operator, the liquid outlet 330 is controlled to inject liquid into the preparation bag, and the operation information corresponding to the liquid injection stage is recorded and stored, where the operation information includes one or more of the liquid preparation task information, operator information, time information, operation type, and liquid preparation process information.

[0099] Optionally, the control device 310 obtains the liquid temperature corresponding to each liquid injection stage through the interaction interface configured on the control panel, and controls the liquid temperature of the liquid outlet 330.

[0100] Optionally, the control device 310 obtains the lower limit and upper limit of the liquid weight in the preparation bag through the interaction interface configured on the control panel. When the actual liquid weight in the preparation bag is less than the lower limit of the liquid weight, the liquid outlet 330 is controlled to open to inject liquid into the preparation bag. When the actual liquid weight in the preparation bag is greater than the upper limit of the liquid weight, the liquid outlet 330 is controlled to close.

[0101] The liquid preparation system provided by the embodiments of the present invention can execute the liquid preparation method in the disposable liquid preparation scenario provided by any embodiment of the present invention, and has the corresponding functional modules and beneficial effects for executing the method.

[0102] Embodiment 4

[0103] Figure 4 FIG. 10 is a schematic structural diagram of a control device provided by Embodiment 4 of the present invention. The control device 10 is intended to represent various forms of electronic devices, such as, a laptop computer, a desktop computer, a workbench, a personal digital assistant, a server, a blade server, a mainframe computer, a control cabinet, and other suitable automation devices. The control device can also represent various forms of mobile devices, such as, a personal digital processor, a cellular phone, a smart phone, a wearable device (such as a helmet, glasses, a watch, etc.), and other similar computing devices. The components shown herein, their connections and relationships, and their functions are merely examples and are not intended to limit the implementation of the present invention described and / or claimed herein.

[0104] As Figure 4 shown, the control device 10 includes at least one processor 11, and a memory communicatively connected to the at least one processor 11, such as a read-only memory (ROM) 12, a random access memory (RAM) 13, etc. The memory stores a computer program executable by the at least one processor. The processor 11 can perform various appropriate actions and processes according to the computer program stored in the read-only memory (ROM) 12 or the computer program loaded from the storage unit 18 into the random access memory (RAM) 13. In the RAM 13, various programs and data required for the operation of the control device 10 can also be stored. The processor 11, the ROM 12, and the RAM 13 are connected to each other through a bus 14. The input / output (I / O) interface 15 is also connected to the bus 14.

[0105] Multiple components in the control device 10 are connected to the I / O interface 15, including: an input unit 16, such as a keyboard, a mouse, etc.; an output unit 17, such as various types of displays, speakers, etc.; a storage unit 18, such as a disk, an optical disc, etc.; and a communication unit 19, such as a network card, a modem, a wireless communication transceiver, etc. The communication unit 19 allows the control device 10 to exchange information / data with other devices through a computer network such as the Internet and / or various telecommunication networks.

[0106] The processor 11 can be various general-purpose and / or special-purpose processing components with processing and computing capabilities. Some examples of the processor 11 include, but are not limited to, a central processing unit (CPU), a graphics processing unit (GPU), various dedicated artificial intelligence (AI) computing chips, various processors running machine learning model algorithms, a digital signal processor (DSP), and any suitable processor, controller, microcontroller, etc. The processor 11 executes the various methods and processes described above, such as the liquid dispensing method in a single-use liquid dispensing scenario.

[0107] In some embodiments, the liquid dispensing method in a single-use liquid dispensing scenario can be implemented as a computer program, which is tangibly contained in a computer-readable storage medium, such as the storage unit 18. In some embodiments, part or all of the computer program can be loaded and / or installed onto the control device 10 via the ROM 12 and / or the communication unit 19. When the computer program is loaded into the RAM 13 and executed by the processor 11, one or more steps of the liquid dispensing method in the single-use liquid dispensing scenario described above can be executed. Alternatively, in other embodiments, the processor 11 can be configured to execute the liquid dispensing method in a single-use liquid dispensing scenario by any other suitable means (e.g., by means of firmware).

[0108] The various embodiments of the systems and technologies described above in this document can be implemented in digital electronic circuit systems, integrated circuit systems, field-programmable gate arrays (FPGAs), application-specific integrated circuits (ASICs), application-specific standard products (ASSPs), systems-on-a-chip (SOCs), complex programmable logic devices (CPLDs), computer hardware, firmware, software, and / or combinations thereof. These various embodiments can include: being implemented in one or more computer programs that can be executed and / or interpreted on a programmable system including at least one programmable processor, which can be a special-purpose or general-purpose programmable processor, receiving data and instructions from a storage system, at least one input device, and at least one output device, and transmitting the data and instructions to the storage system, the at least one input device, and the at least one output device.

[0109] The computer program for implementing the liquid dispensing method in the disposable liquid dispensing scenario of the present invention can be written in any combination of one or more programming languages. These computer programs can be provided to the processor of a general-purpose computer, a special-purpose computer, or other programmable data processing devices, such that when the computer program is executed by the processor, the functions / operations specified in the flowchart and / or block diagram are implemented. The computer program can be executed entirely on the machine, partially on the machine, executed partially on the machine and partially on a remote machine as an independent software package, or executed entirely on a remote machine or server.

[0110] Embodiment 5

[0111] Embodiment 5 of the present invention further provides a computer-readable storage medium. The computer-readable storage medium stores computer instructions for causing a processor to execute the liquid dispensing method in the disposable liquid dispensing scenario. The method includes:

[0112] In any liquid injection stage, obtain the desired liquid weight of the liquid injection stage and the actual liquid weight of the liquid injection stage; in the case where the actual liquid weight meets the first threshold condition corresponding to the desired liquid weight, control the liquid outlet to inject liquid into the preparation bag based on a multi-period injection mode: in any injection period, when the injection duration of the liquid outlet reaches the set duration of the injection period, control the liquid outlet to close; when the interval condition is met, control the liquid outlet to open for the next injection period until the actual liquid weight of the preparation bag meets the second threshold condition corresponding to the desired liquid weight, and control the liquid outlet to close to complete the liquid injection stage.

[0113] In the context of the present invention, the computer-readable storage medium can be a tangible medium that can contain or store a computer program for use by or in connection with an instruction execution system, apparatus, or device. The computer-readable storage medium can include, but is not limited to, electronic, magnetic, optical, electromagnetic, infrared, or semiconductor systems, apparatuses, or devices, or any suitable combination of the foregoing. Alternatively, the computer-readable storage medium can be a machine-readable signal medium. More specific examples of the machine-readable storage medium would include an electrical connection based on one or more wires, a portable computer disk, a hard disk, a random access memory (RAM), a read-only memory (ROM), an erasable programmable read-only memory (EPROM or flash memory), an optical fiber, a portable compact disc read-only memory (CD-ROM), an optical storage device, a magnetic storage device, or any suitable combination of the foregoing.

[0114] To provide interaction with a user, the systems and techniques described herein can be implemented on a control device having: a display device for displaying information to the user (e.g., a CRT (cathode ray tube) or LCD (liquid crystal display) monitor); and a keyboard and a pointing device (e.g., a mouse or a trackball) through which the user can provide input to the control device. Other kinds of devices can also be used to provide interaction with the user; for example, the feedback provided to the user can be any form of sensory feedback (e.g., visual feedback, auditory feedback, or tactile feedback); and input from the user can be received in any form (including acoustic input, voice input, or tactile input).

[0115] The systems and techniques described herein can be implemented in a computing system including backend components (e.g., as a data server), or a computing system including middleware components (e.g., an application server), or a computing system including frontend components (e.g., a user computer having a graphical user interface or a web browser through which the user can interact with an implementation of the systems and techniques described herein), or a computing system including any combination of such backend components, middleware components, or frontend components. The components of the system can be interconnected by digital data communication in any form or medium (e.g., a communication network). Examples of communication networks include: local area network (LAN), wide area network (WAN), blockchain network, and the Internet.

[0116] A computing system can include a client and a server. The client and the server are generally remote from each other and typically interact through a communication network. The client-server relationship is created by computer programs running on the respective computers and having a client-server relationship with each other. The server can be a cloud server, also known as a cloud computing server or a cloud host, which is a host product in the cloud computing service system and solves the defects of difficult management and weak business scalability existing in traditional physical hosts and VPS services.

[0117] It should be understood that the various forms of processes shown above can be used, with steps reordered, added, or deleted. For example, the steps recited in the present invention can be executed in parallel, sequentially, or in a different order, as long as the desired results of the technical solution of the present invention can be achieved, and no limitation is made herein.

[0118] The above specific embodiments do not constitute a limitation on the protection scope of the present invention. Those skilled in the art should understand that various modifications, combinations, sub-combinations, and substitutions can be made according to design requirements and other factors. Any modifications, equivalent substitutions, and improvements made within the spirit and principles of the present invention shall be included within the protection scope of the present invention.

Claims

1. A liquid preparation method in a disposable liquid preparation scenario, characterized in that, A disposable preparation bag is provided in the liquid preparation container, and the liquid outlet of the liquid preparation system injects liquid into the preparation bag. The weighing device in the liquid preparation system is used to collect the weight of the liquid in the preparation bag; The method includes: In any liquid injection stage, obtain the expected liquid weight of the liquid injection stage and the actual liquid weight of the liquid injection stage; When the actual liquid weight meets the first threshold condition corresponding to the expected liquid weight, control the liquid outlet to inject liquid into the preparation bag based on the multi-period injection mode: in any injection period, when the injection duration of the liquid outlet reaches the set duration of the injection period, control the liquid outlet to close; when the interval condition is met, control the liquid outlet to open for the next injection period until the actual liquid weight of the preparation bag meets the second threshold condition corresponding to the expected liquid weight, and control the liquid outlet to close to complete the liquid injection stage.

2. The method according to claim 1, characterized in that The liquid outlet is configured with a control switch; The method further includes: When the injection duration of the liquid outlet reaches the set duration of the injection period, generate a closing signal, send the closing signal to the control switch, and control the control switch to close; When the interval condition is met, generate a start signal, send the start signal to the control switch, and control the control switch to open.

3. The method according to claim 1, wherein The set durations corresponding to different injection periods are the same; Or, the set durations corresponding to different injection periods are the same or different, and the set duration corresponding to the later injection period is less than or equal to the set duration corresponding to the earlier injection period; Or, the set duration corresponding to each injection period is determined based on a preset ratio of the expected liquid weight and the flow rate of the liquid outlet.

4. The method according to claim 1, characterized in that, The interval condition includes one or more of the following: The closing duration of the liquid outlet meets a preset interval duration; After the liquid outlet closes, the actual liquid weight of the preparation bag reaches a stable state.

5. The method according to claim 1, wherein The method further includes: In any of the liquid injection stages, read the operator information and perform permission verification on the operator information; When the permission verification of the operator information is successful, in response to the injection trigger operation of the operator, control the liquid outlet to inject liquid into the preparation bag, and record and store the operation information corresponding to the liquid injection stage, where the operation information includes one or more of the liquid preparation task information, operator information, time information, operation type, and liquid preparation process information.

6. The method according to claim 5, characterized in that, A control panel is provided on the control device of the liquid preparation system; a start button is provided on the control panel, and the injection trigger operation is a trigger operation on the start button; An interactive interface is further configured on the control panel; The method further includes: Obtain the expected liquid weight of each liquid injection stage through the interactive interface; and display the actual liquid weight of the liquid injection stage on the interactive interface.

7. The method according to claim 1 or 5, characterized in that The liquid injection stage includes an initial injection stage and a constant volume injection stage.

8. A liquid preparation system, characterized in that, It includes: A control device, a liquid preparation container, and a liquid outlet. The liquid preparation container is configured with a weighing device, and a disposable preparation bag is provided in the liquid preparation container; The control device is communicatively connected to the weighing device of the liquid dispensing container and the control switch of the liquid outlet respectively; The control device controls the liquid outlet to inject liquid into the preparation bag during any liquid injection stage, and receives the actual liquid weight collected by the weighing device; When the actual liquid weight meets the first threshold condition corresponding to the expected liquid weight in the liquid injection stage, the liquid outlet is controlled to inject liquid into the preparation bag based on a multi-period injection mode: during any injection period, when the injection duration of the liquid outlet reaches the set duration of the injection period, the liquid outlet is controlled to close; when the interval condition is met, the liquid outlet is controlled to open for the next injection period until the actual liquid weight of the preparation bag meets the second threshold condition corresponding to the expected liquid weight, and the liquid outlet is controlled to close to complete the liquid injection stage.

9. A control device, characterized in that, The control device includes: At least one processor; and A memory communicatively connected to the at least one processor; wherein, The memory stores a computer program executable by the at least one processor, and the computer program is executed by the at least one processor to enable the at least one processor to execute the liquid dispensing method in the single-use liquid dispensing scenario described in any one of claims 1-7.

10. A computer-readable storage medium, characterized in that, The computer-readable storage medium stores computer instructions for causing a processor to implement the liquid dispensing method in the single-use liquid dispensing scenario described in any one of claims 1-7 when executed.

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