Pharmaceutical composition of health care wine

Through a specific proportion of traditional Chinese medicinal materials and health care wine to harmonize qi and blood, complex diseases of middle-aged and elderly people are solved, yin and yang balance is achieved, and the symptoms of cough and asthma are relieved, immune function is improved, and health and longevity is promoted.

CN120459250APending Publication Date: 2025-08-12NING JIANGANG TRADITIONAL CHINESE MEDICINE CLINIC IN XINGHUALING DISTRICT TAIYUAN CITY
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Patent Information

Application Number
CN202510709219.7
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-05-29
Publication Date
2025-08-12

AI Technical Summary

Technical Problem

There is a single formula for health wine for middle-aged and elderly people, and it is impossible to warm yang and disperse cold and nourish yin and moisten dryness, resulting in less significant improvement effects on complex diseases such as phlegm and dampness congestion in lung cough and asthma, kidney yang deficiency in frequent urination.

Method used

A pharmaceutical composition is adopted, including ginseng, deer antler, Amomum villossum, male cloves, Dayun, Cuscuta, Suoyang, Epimedium, wolfberry, Eucommia ulmoides, Achyranthes stomata, Yizhiren, Raw Rehmannia, Cooked Rehmannia, Cordyceps sinensis, honey, Asparagus, mulberries, Poria cocos and other Chinese medicinal materials, and is prepared through specific preparation and soaking processes to make health care wine. Combined with Xiaoqinglong Decoction or Erchen Decoction, it harmonizes qi and blood and achieves a balance of yin and yang.

Benefits of technology

It significantly alleviates the cough and asthma symptoms in middle-aged and elderly people, improves immune function, promotes physical health, achieves the fullness of positive energy, and achieves the therapeutic effect of "positive energy is stored inside, and evil cannot be done", reflecting the principle of "supplementing the body and eliminating evil" in traditional Chinese medicine theory.

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Abstract

The invention relates to the technical field of traditional Chinese medicinal material combination medicines, and discloses a pharmaceutical composition of health-preserving health-care wine, which is prepared by combining and refining the following medicines in parts by weight: ginseng, cornu cervi pantotrichum, fructus amomi, flos caryophylli, herba cistanches, semen cuscutae, cynomorium songaricum, herba epimedii, fructus lycii, eucommia ulmoides, radix achyranthis bidentatae, fructus alpiniae oxyphyllae, radix rehmanniae, radix rehmanniae preparata, cordyceps sinensis, honey, radix asparagi, mulberry and poria cocos. The traditional Chinese medicine composition has positive influence on the body health of the middle-aged and elderly people, and can achieve the effect of prolonging life by warming the lung, dispelling cold, increasing yang qi, eliminating cold qi and cold dampness in the body, strengthening the body function and improving the immune function.
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Description

Technical Field

[0001] The present invention belongs to the field of Chinese medicinal material combination medicines, in particular to the field of health-care medicinal wines, specifically to a medicinal composition of health-care wines. Background Art

[0002] Nowadays, with the aging of the population, the emergence of sub-healthy constitutions is more common among the middle-aged and elderly population. According to clinical observations, people over 60 years old often have the pathological characteristics of Qi and blood deficiency and insufficient Yang Qi. Common symptoms include cough, asthma, chest tightness, and pain in the waist and legs. Modern medical research has confirmed that this phenomenon is mainly attributed to the inadequacy of health care among the middle-aged and elderly population. Such symptoms are closely related to the decline of the body's immune function and the internal accumulation of cold, dampness, and phlegm, leading to Qi and blood deficiency. If not taken seriously, being in a sub-healthy state for a long time will further lead to physical weakness, and then produce cold, which induces the formation of phlegm and dampness. In clinical practice, many cases have been observed to show symptoms such as frequent coughing, thick sputum, shortness of breath, and phlegm in the throat, accompanied by wheezing, chest tightness as if blocked, pale complexion, chills and coldness, and the symptoms are aggravated after being exposed to cold. These symptoms indicate that the patient has a pathological state of phlegm blocking the lungs and cold fluid lurking inside the body.

[0003] The pathological mechanisms of cough and asthma are primarily attributed to insufficient Yang Qi, the upward movement of pathogenic cold, phlegm and turbidity blocking the lungs, and the lurking of cold fluids within. Zhu Danxi once stated, "Asthma is primarily caused by pathogenic phlegm," emphasizing that "phlegm is the root cause of all illnesses."

[0004] Currently, most health wines targeting the sub-health of middle-aged and elderly people on the market use a single tonic ingredient (such as ginseng and wolfberry). Although they have a certain effect of replenishing qi and nourishing blood, they have the following problems: Single formula: Ignoring the TCM principles of "dual tonification of yin and yang" and "strengthening the body's resistance and eliminating pathogenic factors," it is difficult to balance the synergistic effects of warming yang and dispelling cold with nourishing yin and moistening dryness. Limitations in efficacy: Existing products have no significant effect on improving complex symptoms such as cough and asthma due to phlegm and dampness blocking the lungs, and frequent urination due to kidney yang deficiency, and are unable to achieve the functions of warming the lungs and dispersing cold, resolving phlegm and relieving asthma, and tonifying the kidneys and strengthening the foundation.

[0005] In order to solve the above problems, the present invention provides a pharmaceutical composition of health-care wine. Summary of the Invention

[0006] The present invention aims to solve the problem that the middle-aged and elderly people currently do not pay enough attention to the cold-induced phlegm and dampness in terms of health preservation, which leads to symptoms such as frequent coughing, thick phlegm, rapid breathing, phlegm sound in the throat, and accompanied by wheezing, chest tightness as if blocked, pale complexion, and chills. The health-care wine for the middle-aged and elderly has a single formula and has a certain effect of replenishing qi and nourishing blood, but cannot take into account other factors and has no significant effect on improving complex symptoms. The present invention provides a pharmaceutical composition of health-care wine.

[0007] The present invention is implemented by the following technologies: The present invention provides a pharmaceutical composition of health-care wine, which is prepared by refining the following medicinal materials in the following weight ratios, specifically comprising: Ginseng, deer antler, Amomum villosum, clove, dwarf yew, dodder seed, cynomorium songaricum, epimedium, wolfberry, eucommia bark, ox knee, alpinia oxyphylla, raw rehmannia root, cooked rehmannia root, cordyceps sinensis, honey, asparagus cochinchinensis, mulberry, poria cocos.

[0008] The specific content is 10~100 parts of ginseng, 10~100 parts of deer antler, 10~100 parts of Amomum villosum, 5~50 parts of cloves, 20~200 parts of dayun, 10~100 parts of dodder seeds, 10~100 parts of cynomorium songaricum, 10~100 parts of epimedium, 10~100 parts of wolfberry, 10~100 parts of eucommia, 10~100 parts of Achyranthes bidentata, 10~100 parts of Alpinia oxyphylla, 20~200 parts of raw rehmannia, 20~200 parts of cooked rehmannia, 10~100 parts of cordyceps, 20~200 parts of honey, 10~100 parts of asparagus, 20~200 parts of mulberry, and 10~200 parts of poria. The number of parts is measured by weight in grams.

[0009] The drug combination is prepared by the following preparation process, comprising the following steps: S1. Take the medicinal materials except honey and process them in a standardized manner. The standardization is based on the standards stipulated in the national pharmacopoeia. Among them, deer antler is made into vinegar, which can enhance the effect of tonifying kidney yang, benefiting essence and blood, and strengthening bones and muscles; Amomum villosum is fried with salt, which can enhance the effect of removing dampness, stimulating appetite, promoting qi and warming the middle; Cloves are fried, which can warm the middle and reduce adverse effects, warm the kidney and assist yang; Dayun is made into milk, which can tonify the kidney and assist yang, moisten the intestines and relieve constipation; Epimedium is made into mutton oil, which focuses on tonifying the kidney and strengthening yang, Dispel wind and dampness; Eucommia ulmoides and Alpinia oxyphylla are both made with salt, among which Eucommia ulmoides mainly nourishes the liver and kidneys, strengthens the tendons and bones, while Alpinia oxyphylla warms the spleen and appetite, controls saliva, warms the kidneys, consolidates essence and reduces urine; Cuscuta chinensis, Cynomorium songaricum, Achyranthes bidentata and Rehmannia glutinosa are made into wine, among which Cuscuta chinensis nourishes yang and yin, consolidates essence and reduces urine, improves eyesight and stops diarrhea, Cynomorium songaricum nourishes the kidneys and aids yang, moistens the intestines and promotes bowel movements, Achyranthes bidentata activates blood circulation and removes blood stasis, nourishes the liver and kidneys, strengthens the tendons and bones, promotes diuresis and relieves stranguria, and guides blood downward, while Rehmannia glutinosa nourishes yin, replenishes essence and benefits marrow.

[0010] Ginseng has the effect of replenishing vital energy, restoring pulse and strengthening deficiency; Cordyceps sinensis can nourish the kidneys and lungs, stop bleeding and resolve phlegm; Rehmannia glutinosa can clear away heat and cool blood, nourish yin and produce fluid; mulberry is good at nourishing yin and blood, producing fluid and moistening the intestines; Poria cocos can strengthen the spleen and eliminate dampness, calm the mind and soothe the nerves; Asparagus cochinchinensis is good at clearing the lungs and reducing fire, nourishing yin and moistening dryness; wolfberry nourishes the liver and kidneys, improves essence and eyesight and moistens the lungs.

[0011] S2. Put the medicinal materials prepared in step S1 into a spun cotton bag and soak them in 60-proof pure grain liquor for 60 days. The mass ratio of the prepared medicinal materials to the pure grain liquor is 25:1. The soaking liquor is retained for later use.

[0012] S3. Take out the medicinal materials from the cotton-spun bag, place them in pure water, and boil them for 1.5 hours. After boiling, pour all of them back into the soaking wine.

[0013] S4. At the same time, heat the honey to boiling, then filter and remove impurities, and add it to the soaking wine in proportion. Honey can replenish the middle and relieve urgency, moisten the lungs and relieve cough, and lubricate the intestines and promote bowel movements. Continue soaking for 30 days.

[0014] S5. Filling.

[0015] In this application, ginseng has a significant effect of replenishing vital energy, deer antler is good at replenishing yang, benefiting essence and blood, and strengthening bones and muscles, while cordyceps is outstanding in tonifying the kidney and lung, stopping bleeding and resolving phlegm. The use of these three medicinal materials in combination can effectively support the positive energy; the enhancement of positive energy helps to expel the cold evil in the body, thereby playing the role of warming the lungs and dispersing cold. On this basis, the symptoms of cough and asthma can be effectively relieved. Further add Amomum villosum to eliminate dampness and promote qi circulation; Clove to reduce adverse reactions and warm the kidneys and assist yang; Alpinia oxyphylla to warm the spleen and stimulate the appetite, control saliva, warm the kidneys and consolidate essence and reduce urine; Rhizoma Polygoni Multiflori to moisten the intestines and promote bowel movements; Honey to replenish the middle and relieve urgency, moisten the lungs; Poria to strengthen the spleen and eliminate dampness, thereby eliminating the source of phlegm. The comprehensive use of the above-mentioned drugs can achieve the effects of warming the lungs and dispersing cold, resolving phlegm and relieving asthma, and then harmonize qi and blood, enrich positive energy, achieve yin and yang balance, and reach the upper and lower qi mechanisms, ultimately making the cough and asthma symptoms fundamentally improved.

[0016] This application aims to nourish the kidney yang, warm and dispel the cold pathogen in the lungs, and at the same time strengthen the spleen to eliminate dampness and eliminate phlegm. Therefore, through this treatment strategy, asthma symptoms can be alleviated and the vital energy can be replenished, thus achieving the therapeutic effect of "vital energy is stored inside, and the evil cannot enter", which embodies the principle of "supporting the vital energy and eliminating the evil" in traditional Chinese medicine theory.

[0017] When the present invention is used to treat middle-aged and elderly patients with cough and asthma, combined use of Xiaoqinglong Decoction or Erchen Decoction can achieve better therapeutic effects based on the patient's condition. For middle-aged and elderly patients with more sputum secretion, this application combined with Erchen Decoction can enhance the cough and phlegm-relieving effect, and the effect is more significant. For middle-aged and elderly patients with more severe asthma symptoms, this application combined with Xiaoqinglong Decoction can enhance the asthma-relieving and cold-relieving effect, and the effect is more significant.

[0018] Compared with the prior art, the present invention has the following beneficial effects: The pharmaceutical composition of the health-care wine provided by the present application is as stated in the Yellow Emperor's Classic of Internal Medicine: "When righteousness is stored inside, evil cannot invade." The present invention is based on the theoretical basis of strengthening the righteousness and eliminating evil, and aims to nourish the kidney yang, warm and dispel the cold evil in the lungs, and at the same time strengthen the spleen to eliminate dampness and phlegm. Through the therapeutic principles of warming the lungs to dispel cold, resolving phlegm and relieving asthma, the immune function of the middle-aged and elderly people is improved, and the yang energy is enhanced. Long-term use of the present application can relieve asthma symptoms and enrich righteousness, thereby achieving the therapeutic effect of "when righteousness is stored inside, evil cannot invade", reflecting the principle of "strengthening the righteousness and eliminating evil" in traditional Chinese medicine theory, in order to achieve good health and longevity.

[0019] To achieve comprehensive physical health conditioning, this application uses Epimedium to nourish the kidneys and strengthen yang, dispel wind and dampness; Eucommia ulmoides to nourish the liver and kidneys and strengthen the tendons and bones; Achyranthes bidentata to promote blood circulation and remove blood stasis, nourish the liver and kidneys, strengthen the tendons and bones, and promote diuresis and relieve stranguria; Cuscuta chinensis to nourish yang and replenish yin, consolidate essence and reduce urination; Cynomorium songaricum to nourish the kidneys and support yang, and moisten the intestines and promote bowel movements. In addition, it also contains yin-nourishing and body fluid-invigorating herbs such as Rehmannia glutinosa, Rehmannia glutinosa, Asparagus cochinchinensis, Lycium barbarum, and Mulberry, which are intended to nourish kidney yin. The entire prescription compatibility follows the principles of the holistic concept of traditional Chinese medicine, and through the dual tonification of yin and yang, strengthening the body and eliminating evil, it achieves the harmony of qi and blood, and the balance of yin and yang, thereby preventing disease and promoting health and longevity. DETAILED DESCRIPTION

[0020] The specific embodiments of the present invention are described in detail below.

[0021] The medicinal composition of health-care wine is prepared by refining the following medicinal materials in the following weight ratios, specifically comprising: Ginseng 10~100g, deer antler 10~100g, Amomum villosum 10~100g, clove 5~50g, dayun 20~200g, dodder seed 10~100g, cynomorium songaricum 10~100g, epimedium 10~100g, wolfberry 10~100g, eucommia ulmoides 10~100g, Achyranthes bidentata 10~100g, Alpinia oxyphylla 10~100g, raw rehmannia glutinosa 20~200g, cooked rehmannia glutinosa 20~200g, cordyceps sinensis 10~100g, honey 20~200g, asparagus cochinchinensis 10~100g, mulberry 20~200g, poria 10~200g.

[0022] The drug combination is prepared by the following preparation process, comprising the following steps: S1. Take the medicinal materials except honey and carry out standardized processing. The standardization is based on the standards specified in the national pharmacopoeia. Among them, take deer antler to be processed with vinegar, take Amomum villosum to be fried with salt, take cloves to be fried, take Dayun to be processed with milk, take Epimedium to be processed with sheep oil, take Eucommia ulmoides and Alpinia oxyphylla to be processed with salt, take Cuscuta chinensis, Cynomorium songaricum, Achyranthes bidentata and Rehmannia glutinosa to be processed with wine.

[0023] S2. Put the medicinal materials prepared in step S1 into a spun cotton bag and soak them in 60-proof pure grain liquor for 60 days. The mass ratio of the prepared medicinal materials to the pure grain liquor is 25:1. The soaking liquor is retained for later use.

[0024] S3. Take out the medicinal materials from the cotton-spun bag, place them in pure water, and boil them for 1.5 hours. After boiling, pour all of them back into the soaking wine.

[0025] S4. At the same time, take 20-200g of honey and heat it to boiling, then filter it to remove impurities, and add it to the soaking wine in proportion. Honey can replenish the middle and relieve urgency, moisten the lungs and relieve cough, and lubricate the intestines and promote bowel movements. Continue soaking for 30 days.

[0026] S5. Filling. Clinical Cases:

[0027] Su Moumou, male, 68 years old, was diagnosed with kidney qi deficiency, frequent urination and asthma. He was treated with the medicinal wine of the present invention combined with Xiaoqinglong Decoction. After drinking it continuously for one month, the above symptoms disappeared.

[0028] Zhang, a 62-year-old female, suffered from lumbago and frequent urination. The symptom was relieved after 20 days of continuous drinking of the medicinal wine of the present invention.

[0029] Liu Junqing, female, 61 years old, suffered from cough, asthma and pain in waist and legs. She was treated with the medicinal wine of the present invention combined with Xiaoqinglong Decoction, and after one month of treatment, the symptoms disappeared.

[0030] Ms. Hao, 71 years old, had symptoms of cough, asthma and chest tightness. She was treated with the medicinal wine of the present invention in combination with Xiaoqinglong Decoction, and her symptoms disappeared after one month.

[0031] Gao, female, 68 years old, had symptoms of cough, asthma, frequent urination and back pain. She was treated with the medicinal wine of the present invention combined with Xiaoqinglong Decoction, and her symptoms disappeared after one month.

[0032] Mr. Li, male, 78 years old, had symptoms of frequent urination and lumbago. He was treated with the medicinal wine of the present invention, and the symptoms disappeared after one month.

[0033] Zhang, a 72-year-old female, suffered from frequent urination and asthma. She was treated with the medicinal wine of the present invention combined with Xiaoqinglong Decoction, and her symptoms disappeared after one month.

[0034] Mr. Li, a 74-year-old male, suffered from urinary urgency, frequent urination and asthma. He was treated with the medicinal wine of the present invention combined with Xiaoqinglong Decoction, and his symptoms disappeared after one month.

[0035] Gao, a 76-year-old male, suffered from urinary urgency, frequent urination and asthma. He was treated with the medicinal wine of the present invention combined with Xiaoqinglong Decoction, and his symptoms disappeared after one month. Statistical analysis:

[0036] This embodiment is used to treat patients with cough and asthma, while the comparative example uses salbutamol and aminophylline for treatment. Statistical analysis results of the treatment effects of this embodiment showed that the total effective rate of the embodiment (n=60) was 95% (57 / 60), of which 36 cases (60%) were markedly effective, 21 cases (35%) were effective, and only 3 cases (5%) were ineffective. The total effective rate of the control group (n=38) was 34.21% (13 / 38), with 3 cases (7.89%) showing marked effect, 10 cases (26.32%) showing effect, and 25 cases (65.79%) showing ineffectiveness.

[0037] Based on the efficacy data of the embodiment and the comparative example, the chi-square test was used for statistical analysis. The results showed that there was a significant difference in the total effective rate between the two groups (χ²=51.6, df=1, p<0.001); The efficacy of the embodiment (60%) was significantly higher than that of the comparative example (7.89%), and the calculated result was χ²=28.3, p<0.001; There is a significant difference between marked efficiency and effective rate, which is statistically significant.

[0038] In summary, the therapeutic effect of the embodiment is significantly better than that of the comparative example, which has both statistical and clinical significance.

[0039] The scope of protection claimed by the present invention is not limited to the above specific embodiments. For those skilled in the art, the present invention may have various variations and modifications. Any modifications, improvements and equivalent substitutions made within the concept and principle of the present invention should be included in the scope of protection of the present invention.

Claims

1. A pharmaceutical composition of health-care wine, characterized in that: The Chinese herbal medicine composition is refined from the following medicinal combinations in the following weight ratios, specifically including: Ginseng, deer antler, Amomum villosum, clove, dwarf yew, dodder seed, cynomorium songaricum, epimedium, wolfberry, eucommia bark, ox knee, alpinia oxyphylla, raw rehmannia root, cooked rehmannia root, cordyceps sinensis, honey, asparagus cochinchinensis, mulberry, poria cocos.

2. The pharmaceutical composition of health-care wine according to claim 1, characterized in that: The specific content is 10-100 parts of ginseng, 10-100 parts of deer antler, 10-100 parts of amomum villosum, 5-50 parts of cloves, 20-200 parts of yun, 10-100 parts of dodder seeds, 10-100 parts of cynomorium songaricum, 10-100 parts of epimedium, 10-100 parts of wolfberry, 10-100 parts of eucommia, 10-100 parts of achyranthes bidentata, 10-100 parts of alpinia oxyphylla, 20-200 parts of raw rehmannia, 20-200 parts of cooked rehmannia, 10-100 parts of cordyceps, 20-200 parts of honey, 10-100 parts of asparagus, 20-200 parts of mulberries, and 10-200 parts of poria, and the number of parts is measured by gram weight.

3. The pharmaceutical composition of health-care wine according to claim 2, characterized in that: The drug combination is prepared by the following preparation process, comprising the following steps: S1. Take the medicinal materials except honey and process them in a standardized manner; S2. Put the medicinal materials prepared in step S1 into a spun cotton bag, soak them in 60-proof pure grain liquor for 60 days, and keep the soaking liquor for later use; S3. Take out the medicinal materials from the cotton-spun bag, place them in pure water, and boil them for 1.5 hours. After boiling, pour all of them back into the soaking wine; S4. Meanwhile, heat the honey to boiling, filter and remove impurities, add it to the soaking wine in proportion, and continue soaking for 30 days; S5. Filling.

4. The pharmaceutical composition of health-care wine according to claim 3, characterized in that: In step S2, the mass ratio of the processed medicinal materials to the pure grain liquor is 25:

1.

5. The pharmaceutical composition of health-care wine according to claim 3, characterized in that: In step S1, velvet antler is processed with vinegar, Amomum villosum is fried with salt, cloves are fried, Dayun is processed with milk, Epimedium is processed with sheep oil, Eucommia ulmoides and Alpinia oxyphylla are processed with salt, Cuscuta chinensis, Cynomorium songaricum, Achyranthes bidentata and Rehmannia glutinosa are processed with wine.