Ultrasonic antibacterial device for bone infection

Through ultrasonic antibacterial devices, the ultrasonic cavitation effect is used to destroy bacterial biofilms at bone infection sites, solving the problem of poor antibiotic penetration in the prior art, achieving efficient treatment of bone infection, and reducing the patient's pain and recurrence risk.

CN120459554AActive Publication Date: 2025-08-12FIRST HOSPITAL AFFILIATED TO GENERAL HOSPITAL OF PLA
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Patent Information

Application Number
CN202510716369.0
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-05-30
Publication Date
2025-08-12
Estimated Expiration
2045-05-30

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Abstract

The invention belongs to the technical field of medical instruments, and discloses an ultrasonic antibacterial device for treating bone infection, which comprises a main control shell and a minimally invasive catheter. A guide wire control module, an ultrasonic control module and a medium liquid storage cavity are arranged in the main control shell, the minimally invasive catheter is of a double-layer structure, and a guide wire is arranged in the minimally invasive catheter. An annular ultrasonic medium cavity is formed in the front end of the minimally invasive catheter, the ultrasonic medium cavity is used for being filled with an ultrasonic medium solution, ultrasonic generation assemblies are arranged in the minimally invasive catheter in an annular array mode, piezoelectric wafers are arranged in the ultrasonic generation assemblies, and the piezoelectric wafers are used for achieving electricity-sound conversion to achieve emission and receiving of ultrasonic waves. When the device is used, an infected part is accurately positioned through the guide wire, ultrasonic waves are emitted by utilizing the ultrasonic generation assembly, and a bacterial biofilm structure is destroyed by utilizing an ultrasonic cavitation effect, so that the effects of removing the bacterial biofilm and performing antibacterial treatment are achieved. The device is suitable for bone infection treatment.
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Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and in particular to an ultrasonic antibacterial device for bone infection. Background Art

[0002] Bone infection is a serious complication during orthopedic surgery, potentially leading to implant failure, bone destruction, and even the need for repeated surgeries for implant removal and debridement. Currently, treatments for bone infection rely primarily on antibiotics and debridement, but these methods have limitations. Antibiotics have difficulty penetrating effectively, and bacteria can form biofilms on bone tissue and implant surfaces, significantly reducing antibiotic penetration and making the infection difficult to eradicate. Surgery often requires removal of infected tissue and even the implant, which can increase patient pain and hinder bone healing.

[0003] Therefore, in order to solve the above problems, the present invention proposes an ultrasonic antibacterial device for bone infection, which utilizes the ultrasonic cavitation effect and ultrasonic enhanced antibacterial effect to effectively remove biofilm and enhance the local anti-infection treatment effect without damaging bone tissue and implants. Summary of the Invention

[0004] The present invention is intended to provide an ultrasonic antibacterial device for bone infection to solve the problem that the treatment process of bone infection in the prior art is not effective.

[0005] In order to achieve the above object, the present invention provides the following technical solutions:

[0006] An ultrasonic antibacterial device for bone infection includes a main control shell and a minimally invasive catheter. The main control shell is connected to the minimally invasive catheter. The main control shell includes a guide wire control module, an ultrasonic control module and an ultrasonic medium storage chamber. The ultrasonic medium storage chamber is provided with a micro-circulation pump, which is controlled by an external pump control module. The minimally invasive catheter is a double-layer tube including a guide wire chamber and a line chamber. A guide wire is connected to the guide wire chamber. The line chamber is used to pass pipes and lines. The guide wire is connected to the guide wire control module. The guide wire control module is used to control the movement of the guide wire. The front end of the minimally invasive catheter is provided with a ring-shaped ultrasonic medium chamber. The ultrasonic medium storage chamber is provided with a micro-circulation pump. The micro-circulation pump is controlled by an external pump control module. The acoustic medium cavity is connected to the ultrasonic medium storage cavity through a circulation tube. The circulation tube is located in the circuit cavity. The micro-circulation pump is connected to the circulation tube. Several ultrasonic generating components are connected in the circuit cavity. The ultrasonic generating components are connected to the outside of the ultrasonic medium cavity. The ultrasonic generating components include a shell. A piezoelectric chip is connected to the inside of the shell. The piezoelectric chip is connected to the ultrasonic control module through a circuit input line. The shell is connected to the ultrasonic control module through a ground wire. The circuit input line and the ground wire are located in the circuit cavity. The ultrasonic control module, the circuit input line, the piezoelectric chip, the shell and the ground wire form an ultrasonic generating circuit.

[0007] Furthermore, a circular array of ultrasonic generating components is arranged outside the ultrasonic medium cavity, and multiple groups of circular array ultrasonic generating components are provided.

[0008] Furthermore, an absorbent filler is provided inside the shell, and the absorbent filler is provided on a side of the piezoelectric chip close to the guide wire.

[0009] Furthermore, the ultrasonic medium cavity and the ultrasonic medium storage cavity are used to be filled with solutions such as hydrogels and slow-release antibacterial solutions that can improve the local conduction efficiency of ultrasonic energy.

[0010] Furthermore, the ultrasound control module can adjust the frequency of ultrasound generation.

[0011] The principle and beneficial effects of the present technical solution: A guidewire is provided inside the minimally invasive catheter of the present invention, and the movement of the guidewire is controlled by the guidewire control module. The guidewire drives the minimally invasive catheter to move, and the minimally invasive catheter can reach the site of bone infection. The ultrasonic control module of the present invention is connected to the piezoelectric chip through a circuit input line. The ultrasonic control module controls the piezoelectric chip to release ultrasonic waves of different frequencies. The ultrasonic cavitation effect generated by the ultrasonic wave forms microbubbles in the infected area. The microbubbles burst to release high-energy microjets, which physically destroy the bacterial biofilm and improve the antibacterial treatment effect. At the same time, the present invention is also provided with an ultrasonic medium layer. When the ultrasonic wave is released, it passes through the ultrasonic medium layer, which can effectively improve the conduction efficiency of the ultrasonic energy and improve the effect of ultrasonic treatment. BRIEF DESCRIPTION OF THE DRAWINGS

[0012] Figure 1 It is a structural schematic diagram of the present invention;

[0013] Figure 2 This is a cross-sectional view of the interior of the main control housing of the present invention;

[0014] Figure 3 This is an axial cross-sectional view of the top end of the minimally invasive catheter of the present invention;

[0015] Figure 4 This is a longitudinal cross-sectional view of the top end of the minimally invasive catheter of the present invention;

[0016] Figure 5 It is a structural diagram of the ultrasonic generating assembly of the present invention;

[0017] In the figure: 1. Main control shell; 2. Minimally invasive catheter; 3. Guidewire control module; 4. Ultrasonic control module; 5. Ultrasonic medium storage chamber; 6. Guidewire chamber; 7. Line chamber; 31. Guidewire; 41. Ultrasonic generating assembly; 42. Shell; 43. Piezoelectric chip; 44. Circuit input line; 45. Ground wire; 46. Absorbent filler; 51. Micro circulation pump; 52. Pump control module; 53. Ultrasonic medium chamber; 54. Circulation pipe. DETAILED DESCRIPTION

[0018] The present invention will be further described in detail below with reference to the accompanying drawings and embodiments:

[0019] like Figure 1-Figure 5As shown, an ultrasonic antibacterial device for bone infection includes a main control shell 1 and a minimally invasive catheter 2. The minimally invasive catheter 2 is connected to the front end of the main control shell 1. A guidewire control module 3, an ultrasonic control module 4 and an ultrasonic medium storage chamber 5 are provided inside the main control shell. The guidewire control module 3 is connected to a guidewire 31. The guidewire control module 3 is used to control the movement of the guidewire 31. The guidewire 31 is provided inside the minimally invasive catheter 2 and connected to the inner wall of the minimally invasive catheter 2. The minimally invasive catheter 2 is a double-layer tube structure with an inner layer of a guidewire cavity 6 and an outer layer of a line cavity 7. The guidewire cavity 6 is used to accommodate the guidewire 31, and the line cavity 7 is used to accommodate a circulation tube 54, a circuit input line 44 and a grounding line 45. 2 is provided with an annular ultrasonic medium cavity 53 at the front end, and the ultrasonic medium cavity 53 is used to fill a solution such as hydrogel, sustained-release antibacterial solution, etc. that can improve the local conduction efficiency of ultrasonic energy. The ultrasonic medium cavity 53 is connected to the ultrasonic medium storage cavity 5 through a circulation pipe 54. A micro-circulation pump 51 is provided in the ultrasonic medium storage cavity 5, and the micro-circulation pump 51 is connected to the circulation pipe 54. The micro-circulation pump 51 is controlled by an external pump control module 52. By controlling the micro-circulation pump 51, the ultrasonic medium solution in the ultrasonic medium storage cavity 5 can be transported to the ultrasonic medium cavity 53, and the ultrasonic medium solution in the ultrasonic medium cavity 53 can also be extracted into the ultrasonic medium storage cavity 5. The ultrasonic medium storage chamber 5 is connected to six ultrasonic generating components 41 in a ring array near the guide wire 31. Every six ultrasonic generating components 41 form a group, and there are four groups in total. The ultrasonic generating component 41 includes a shell 42. A piezoelectric chip 43 is connected to the inside of the shell 42. The shell 42 is connected to the ultrasonic control module 4 through the circuit cavity 7 via the grounding wire 45. The piezoelectric chip 43 is connected to the ultrasonic control module 4 through the circuit cavity 7 via the circuit input line 44. The ultrasonic control module 4, the circuit input line 44, the piezoelectric chip 43, the shell 42 and the grounding wire 45 form an ultrasonic generating circuit. At the same time, an absorption filler 46 is provided on the side of the piezoelectric chip 43 near the guide wire 31. The absorption filler 46 can absorb reflected ultrasonic waves to prevent the reflected ultrasonic waves from interfering with the emitted ultrasonic waves.

[0020] The specific implementation process is as follows: first, the guide wire control module 3 controls the movement of the guide wire 31. Since the guide wire 31 is arranged inside the minimally invasive catheter 2, the movement of the guide wire 31 will drive the minimally invasive catheter 2 to move. By controlling the guide wire 31, the top of the minimally invasive catheter 2 is moved to the bone infection site, and then the ultrasonic control module 4 is turned on. The ultrasonic control module 4 transmits electrical energy to the piezoelectric chip 43 through the circuit input line 44. The piezoelectric chip 43 completes the conversion of electrical energy into mechanical energy, generates ultrasonic release ultrasound, and destroys the bacterial biofilm at the bone infection site, improves the antibacterial treatment effect, and reduces the recurrence of infection. At the same time, the ultrasonic medium cavity 53 is pre-filled with hydrogels, sustained-release antibacterial solutions, and other solutions that can improve the local conduction efficiency of ultrasonic energy. When releasing ultrasound, the ultrasonic transmission efficiency can be enhanced, thereby strengthening the ultrasonic treatment effect.

[0021] The above is only an embodiment of the present invention, and common knowledge such as the specific technical solutions or characteristics in the solution is not described in detail here. For those skilled in the art, without departing from the technical solution of the present invention, several variations and improvements can be made, which should also be regarded as the scope of protection of the present invention, and these will not affect the effect of the implementation of the present invention and the practicality of the patent. The scope of protection required by this application shall be based on the content of its claims, and the specific implementation methods and other records in the description can be used to interpret the content of the claims.

Claims

1. An ultrasonic antibacterial device for bone infection, characterized by: The invention comprises a main control shell (1) and a minimally invasive catheter (2), wherein the main control shell (1) is connected to the minimally invasive catheter (2), wherein the main control shell comprises a guide wire control module (3), an ultrasonic control module (4) and an ultrasonic medium storage chamber (5), wherein a micro-circulation pump (51) is provided in the ultrasonic medium storage chamber (5), and the micro-circulation pump (51) is controlled by an external pump control module (52), wherein the minimally invasive catheter (2) is a double-layer tube comprising a guide wire chamber (6) and a line chamber (7), wherein a guide wire (31) is connected to the guide wire chamber (6), wherein the line chamber (7) is used for passing a pipeline and a line, wherein the guide wire (31) is connected to the guide wire control module (3), wherein the guide wire control module (3) is used for controlling the movement of the guide wire (31), and wherein a ring-shaped ultrasonic medium chamber (53) is provided at the front end of the minimally invasive catheter (2), wherein the ultrasonic medium chamber (53) is connected to the ultrasonic medium storage chamber via a circulation pipe (54). (5) is connected, the circulation pipe (54) is located in the circuit cavity (7), the micro circulation pump (51) is connected to the circulation pipe (54), a plurality of ultrasonic generating components (41) are connected in the circuit cavity (7), the ultrasonic generating components (41) are connected to the outside of the ultrasonic medium cavity (53), the ultrasonic generating components (41) include a shell (42), a piezoelectric chip (43) is connected inside the shell (42), the piezoelectric chip (43) is connected to the ultrasonic control module (4) through a circuit input line (44), the shell (42) is connected to the ultrasonic control module (4) through a grounding line (45), the circuit input line (44) and the grounding line (45) are located in the circuit cavity (7), and the ultrasonic control module (4), the circuit input line (44), the piezoelectric chip (43), the shell (42) and the grounding line (45) form an ultrasonic generating circuit.

2. The ultrasonic antibacterial device for bone infection according to claim 1, characterized in that: The annular array of ultrasonic generating components (41) is arranged outside the ultrasonic medium cavity (53), and multiple groups of annular array ultrasonic generating components (41) are provided.

3. The ultrasonic antibacterial device for bone infection according to claim 1, characterized in that: An absorbent filler (46) is provided inside the shell (42), and the absorbent filler (46) is provided on a side of the piezoelectric chip (43) close to the guide wire (31).

4. The ultrasonic antibacterial device for bone infection according to claim 1, characterized in that: The ultrasonic medium cavity (53) and the ultrasonic medium storage cavity (5) are used to be filled with solutions such as hydrogels and slow-release antibacterial solutions that can improve the local conduction efficiency of ultrasonic energy.

5. The ultrasonic antibacterial device for bone infection according to claim 1, characterized in that: The ultrasonic control module (4) is capable of adjusting the frequency of ultrasonic generation.

Citation Information

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