Rapid treatment equipment for co-immunoprecipitation sample of protein
Through an automated control system and a modularly designed protein immunoprecipitation sample processing equipment, the error and inconsistency problems caused by the existing equipment relying on manual operations are solved, and efficient and accurate sample processing is achieved to meet the needs of high-throughput experimental.
Patent Information
- Application Number
- CN202510737428.2
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-06-04
- Publication Date
- 2025-08-12
AI Technical Summary
The existing immunoprecipitation experimental equipment relies on manual operation, resulting in large experimental errors and high inconsistencies, lack of intelligent monitoring and inaccurate reagent addition, making it difficult to meet the needs of high-throughput experiments.
It adopts an automated control system and modular design, combined with sensors to monitor temperature, liquid level and other parameters in real time, uses an ultrasonic crusher and an automatic conveying system to introduce a central control system to coordinate the operation of each module to achieve full automation and precise regulation.
It improves the reliability and repeatability of the experiment, reduces the operating time, ensures the accuracy of reagent addition and the stability of experimental results, and reduces the need for manual intervention.
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Figure CN120468441A_ABST
Abstract
Description
Technical Field
[0001] The invention relates to the field of biochemical experimental equipment, in particular to a rapid protein immunoprecipitation sample processing device. Background Art
[0002] In protein co-immunoprecipitation (Co-IP) experiments, the sample processing process usually involves multiple complex steps, including protein extraction, immune reaction, washing, elution, and recovery of the target protein. These steps must be carried out under strictly controlled conditions, such as temperature, liquid level, time, and reagent addition. With the continuous increase in scientific research needs, especially in high-throughput experiments, the requirements for experimental automation, accuracy, and high efficiency are also getting higher and higher. However, existing experimental equipment often has many shortcomings when responding to these needs, which to a certain extent restricts the improvement of experimental results and the optimization of efficiency.
[0003] In existing technologies, many co-immunoprecipitation devices still rely on manual operation, especially in critical areas such as temperature control, liquid delivery, and sample transport. Experimenters often need to manually adjust temperature or liquid addition based on experience and manually monitor sample status. This approach is not only prone to human error but also increases uncertainty during the experimental process. Minor deviations in experimental conditions can often have a significant impact on the final results. Therefore, this heavy reliance on manual judgment makes it difficult to ensure experimental accuracy and consistency. Furthermore, existing devices generally lack intelligent monitoring and control systems, and cannot provide real-time feedback on experimental data. For example, the lack of real-time monitoring and automatic adjustment of key parameters such as temperature and liquid level makes it difficult to make quick adjustments during the experiment. Experimenters can only identify problems through external observation or post-analysis, missing the optimal time to make adjustments, thus affecting experimental results. Furthermore, the reagent addition systems in existing devices also have certain shortcomings. Many devices still use simple manual liquid addition or basic automatic delivery devices. This method cannot accurately control the amount and timing of each reagent addition, and is prone to excessive or insufficient reagent addition, directly affecting the standardization and reproducibility of experiments. In addition, the reagent addition of the device is often run independently and cannot be coordinated with other operation modules, resulting in delays or inconsistencies in certain steps. To this end, those skilled in the art have proposed a rapid protein immunoprecipitation sample processing device to solve the above problems. Summary of the Invention
[0004] In response to the shortcomings of the existing technology, the present invention provides a rapid protein immunoprecipitation sample processing device, which solves the problem that the existing immunoprecipitation experimental equipment is difficult to meet the needs of modern high-throughput experiments and precise scientific research due to its deficiencies in automation, precision control, coordination and intelligence.
[0005] To achieve the above objectives, the present invention is implemented through the following technical solutions: A rapid protein immunoprecipitation sample processing device, comprising a mounting frame, a conveying assembly is provided inside the mounting frame, a plurality of moving assemblies are provided on the upper side of the mounting frame, the moving assembly on the front side is connected to an ultrasonic disruptor, and the remaining moving assemblies are all connected to experimental addition assemblies, a mechanical gripper is installed on the right side of the interior of the mounting frame, a mechanical liquid extraction device is installed on the left side of the interior of the mounting frame, a shaking table is installed on the front side of the interior of the mounting frame, a magnetic frame is installed on the right side of the interior of the mounting frame, a centrifuge is installed on the rear side of the interior of the mounting frame, and a waste liquid placement box is installed on the rear side of the mechanical liquid extraction device;
[0006] The conveying assembly includes an electric guide rail 1, a movable seat 1 is installed on the front side of the electric guide rail 1, and a movable seat 2 is installed on the rear side of the electric guide rail 1. The upper parts of the movable seat 1 and the movable seat 2 are fixedly connected to a fixed frame, and a plurality of electric clamps are installed on the outside of the fixed frame. A sample tube is placed on the upper side of the fixed frame on the front side, and a centrifuge tube is placed on the upper side of the fixed frame on the rear side.
[0007] Preferably, the moving component includes a fixed plate, an electric guide rail 2 is installed on the front side of the fixed plate, a moving seat 3 is installed on the outside of the electric guide rail 2, an electric guide rail 3 is installed on the front side of the moving seat 3, and a moving seat 4 is installed on the outside of the electric guide rail 3.
[0008] Preferably, the experimental addition component includes a delivery pump, which is installed on the front side of the movable seat four, the input end of the delivery pump is fixedly connected to the input pipe, the output end of the delivery pump is fixedly connected to the delivery pipe, and the top of the mounting frame is provided with an antibody tank, a magnetic bead tank, a washing tank, and an elution tank in sequence from front to back.
[0009] Preferably, the electric clamp at the front side limits and fixes the sample tube, and the electric clamp at the rear side limits and fixes the centrifuge tube.
[0010] Preferably, the ultrasonic crusher is installed on the outside of the movable seat four in the front movable assembly, the number of the remaining movable assemblies matches the number of the delivery pumps, and the top ends of the multiple input tubes are respectively connected to the inside of the antibody tank, magnetic bead tank, washing tank, and elution tank.
[0011] Preferably, a plurality of sensors are installed on the left side of the interior of the mounting frame, and the sensors transmit the collected data to a central control system.
[0012] Preferably, temperature control ports are provided on both left and right sides of the interior of the mounting rack, and the temperature control ports are used to control the internal temperature of the mounting rack.
[0013] Preferably, heat dissipation vents are provided on both left and right sides of the exterior of the mounting frame, and a controller is installed on the right side of the exterior of the mounting frame.
[0014] Preferably, a placement rack is installed on the left side of the outside of the mounting rack, and the placement rack is used to place garbage generated by the experiment.
[0015] Preferably, the central control system includes:
[0016] Acquisition module: The acquisition module is responsible for collecting real-time data from various sensors in the equipment and transmitting it to the central control system for further processing;
[0017] Analysis module: The analysis module processes and analyzes the data obtained from the acquisition module to determine whether the equipment is in normal working condition, and generates control instructions based on the analysis results to adjust the operation of the equipment;
[0018] Driver module: The driver module is responsible for receiving control instructions issued by the analysis module and driving the various components of the device to perform corresponding operations according to these instructions.
[0019] The present invention provides a rapid protein immunoprecipitation sample processing device, which has the following beneficial effects:
[0020] 1. This invention utilizes an automated control system that uses multiple sensors to monitor key parameters such as temperature, liquid level, and displacement during the experiment in real time, achieving fully automated and precise control. Compared to existing experimental equipment that relies on manual operation and adjustment, this invention effectively eliminates experimental errors and inconsistencies caused by improper human operation, thereby improving the reliability and repeatability of the experiment.
[0021] 2. This invention combines an ultrasonic disruptor with an automated delivery system to achieve efficient and precise protein extraction. Compared to existing methods that require manual sample handling and are less efficient, this method releases the target protein more rapidly, reduces sample processing time, and improves protein recovery.
[0022] 3. This invention adopts a modular design, combining mobile components with experimental addition components, enabling seamless integration of automatic reagent addition and precise sample delivery, achieving higher work efficiency. Compared with the multi-step manual operation and inefficient reagent addition methods in the prior art, this invention significantly reduces operation time, ensures the accuracy of each reagent addition step, and avoids reagent waste.
[0023] 4. This invention achieves intelligent control of the experimental process by integrating a central control system to coordinate the operation of each module. Compared to existing technical solutions that have simple equipment operations and are difficult to adjust, this invention can automatically adjust the working status of each component, not only improving the adaptability of the equipment, but also effectively reducing the need for manual intervention and operational risks. BRIEF DESCRIPTION OF THE DRAWINGS
[0024] Figure 1 A perspective view of the present invention;
[0025] Figure 2 Schematic diagram of the mechanical gripper structure of the present invention;
[0026] Figure 3 for Figure 1 Enlarged view of point A in the middle;
[0027] Figure 4 It is a schematic structural diagram of the centrifuge of the present invention;
[0028] Figure 5 This is a structural schematic diagram of an electric guide rail according to the present invention;
[0029] Figure 6 for Figure 5 Enlarged view of point B in the middle;
[0030] Figure 7 It is a schematic structural diagram of the delivery pump of the present invention;
[0031] Figure 8 Schematic diagram of the central control system of the present invention.
[0032] Among them, 1. Mounting rack; 2. Conveying assembly; 201. Electric guide rail 1; 202. Moving seat 1; 203. Moving seat 2; 204. Fixed rack; 205. Electric gripper; 206. Sample tube; 207. Centrifuge tube; 3. Moving assembly; 301. Fixed plate; 302. Electric guide rail 2; 303. Moving seat 3; 304. Electric guide rail 3; 305. Moving seat 4; 4. Ultrasonic disruptor; 5. Experimental adding assembly; 501. Conveying pump; 502. Input tube; 503. Conveying tube; 504. Antibody tank; 505. Magnetic bead tank; 506. Washing tank; 507. Elution tank; 6. Mechanical gripper; 7. Mechanical liquid extraction; 8. Shaking table; 9. Magnetic rack; 10. Centrifuge; 11. Waste liquid placement box; 12. Sensor; 13. Temperature control port; 14. Heat dissipation port; 15. Controller; 16. Placement rack. DETAILED DESCRIPTION
[0033] The following will clearly and completely describe the technical solutions in the embodiments of the present invention in conjunction with the drawings in the present specification. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.
[0034] Please see the attached Figure 1 -Attached Figure 4 An embodiment of the present invention provides a rapid processing device for protein immunoprecipitation samples, including a mounting frame 1, a mechanical clamp 6 is installed on the right side of the interior of the mounting frame 1, a mechanical liquid extraction 7 is installed on the left side of the interior of the mounting frame 1, a shaker 8 is installed on the front side of the interior of the mounting frame 1, a magnetic frame 9 is installed on the right side of the interior of the mounting frame 1, a centrifuge 10 is installed on the rear side of the interior of the mounting frame 1, and a waste liquid placement box 11 is installed on the rear side of the mechanical liquid extraction 7; temperature control ports 13 are provided on both the left and right sides of the interior of the mounting frame 1, and the temperature control ports 13 are used to control the internal temperature of the mounting frame 1, heat dissipation ports 14 are provided on both the left and right sides of the exterior of the mounting frame 1, a controller 15 is installed on the right side of the exterior of the mounting frame 1, and a placement rack 16 is installed on the left side of the exterior of the mounting frame 1, and the placement rack 16 is used to place garbage generated by the experiment.
[0035] Specifically, the front and back sides of the mounting frame 1 are transparent, so that the experimenter can directly observe the status of each processing module inside the equipment. A mechanical gripper 6 is installed on the right side of the interior of the mounting frame 1 for grabbing and fixing the sample tube 206 to ensure that it does not move during transportation and processing. A mechanical liquid extraction 7 is installed on the left side of the interior of the mounting frame 1 for removing waste liquid during the experiment to ensure the cleanliness of the experimental environment and the purity of the sample. A shaking table 8 is installed on the front side of the interior of the mounting frame 1 for providing uniform shaking when the sample and reagent are mixed to ensure sufficient reaction between the sample and the reagent. A magnetic stand 9 is installed on the right side of the interior of the mounting frame 1 for separating target proteins by magnetic adsorption of magnetic beads during the immunoprecipitation process. A centrifuge 10 is installed on the rear side of the interior of the mounting frame 1 for separating impurities in the solution or concentrating the target protein. A waste liquid placement box 11 is installed on the rear side of the mechanical liquid extraction 7 for collecting waste liquid generated during the experiment to prevent waste liquid from leaking and contaminating the experimental environment.
[0036] Temperature control ports 13 are provided on both the left and right sides of the interior of the mounting frame 1. The temperature control ports 13 are used to control the internal temperature of the mounting frame 1 to ensure the temperature range required for different experimental steps and avoid protein degradation or inactivation. Heat dissipation ports 14 are provided on both the left and right sides of the exterior of the mounting frame 1. The heat dissipation ports 14 help the equipment to dissipate heat, prevent the equipment from overheating, and ensure its stable operation. A controller 15 is installed on the right side of the exterior of the mounting frame 1. The controller 15 is used to centrally control various modules of the equipment, including temperature regulation, sample delivery, liquid delivery, etc., to ensure that the equipment automatically executes according to a predetermined program. A placement rack 16 is installed on the left side of the exterior of the mounting frame 1. The placement rack 16 is used to place garbage generated during the experiment to ensure the collection and treatment of waste and avoid contamination of the equipment and the experimental environment.
[0037] Please see the attached Figure 1 , Attachment Figure 2 , Attachment Figure 5 and attached Figure 6 A conveying assembly 2 is provided inside the mounting frame 1, and the conveying assembly 2 includes an electric guide rail 201, a movable seat 202 is installed on the front side of the electric guide rail 201, and a movable seat 203 is installed on the rear side of the electric guide rail 201. The upper parts of the movable seat 202 and the movable seat 203 are fixedly connected to a fixed frame 204, and a plurality of electric clamps 205 are installed on the outside of the fixed frame 204. A sample tube 206 is placed on the upper side of the front fixed frame 204, and a centrifuge tube 207 is placed on the upper side of the rear fixed frame 204. The front electric clamp 205 limits and fixes the sample tube 206, and the rear electric clamp 205 limits and fixes the centrifuge tube 207.
[0038] Specifically, a conveying assembly 2 is provided inside the mounting frame 1, and the conveying assembly 2 is used to accurately transport samples from one processing module to another. The conveying assembly 2 includes an electric guide rail 1 201, a movable seat 1 202 is installed on the front side of the electric guide rail 1 201, and a movable seat 203 is installed on the rear side of the electric guide rail 1 201. The upper parts of the movable seat 1 202 and the movable seat 2 203 are fixedly connected to a fixed frame 204. A plurality of electric grippers 205 are installed on the outside of the fixed frame 204. The electric grippers 205 are responsible for grabbing and fixing the sample tube 206 and the centrifuge tube 207 to ensure that the sample does not move during the entire processing process. The sample tube 206 is placed on the upper side of the front fixed frame 204, and the centrifuge tube 207 is placed on the upper side of the rear fixed frame 204. The front electric grippers 205 limit and fix the sample tube 206, and the rear electric grippers 205 limit and fix the centrifuge tube 207. With this structure, the sample tube 206 and the centrifuge tube 207 can maintain stable positioning throughout the entire experiment, avoiding movement or tilting of the sample due to external forces, thereby ensuring the accuracy of the operation and the stability of the experiment.
[0039] Please see the attached Figure 1 , Attachment Figure 3 and attached Figure 7 A plurality of movable components 3 are provided on the upper side of the mounting frame 1, the front movable component 3 is connected to the ultrasonic crusher 4, the movable component 3 includes a fixed plate 301, an electric guide rail 2 302 is installed on the front side of the fixed plate 301, a movable seat 303 is installed on the outside of the electric guide rail 2 302, an electric guide rail 3 304 is installed on the front side of the movable seat 303, a movable seat 4 305 is installed on the outside of the electric guide rail 3 304, and the ultrasonic crusher 4 is installed on the outside of the movable seat 4 305 in the front movable component 3.
[0040] Specifically, the upper side of the mounting frame 1 is provided with a plurality of movable components 3 for realizing the precise transmission of samples between different processing modules. The front movable component 3 is connected to an ultrasonic crusher 4, which is installed on the outside of the movable seat 4 305 in the front movable component 3. The ultrasonic crusher 4, through its high-frequency oscillation, crushes the cell sample and releases the protein therein, facilitating the subsequent immunoprecipitation experiment. The movable component 3 includes a fixed plate 301, the front side of the fixed plate 301 is provided with an electric guide rail 2 302, the outside of the electric guide rail 2 302 is provided with a movable seat 3 303, the front side of the movable seat 3 303 is provided with an electric guide rail 3 304, and the outside of the electric guide rail 3 304 is provided with a movable seat 4 305. Through this structural design, the coordination of multiple electric guide rails and movable seats enables the ultrasonic crusher 4 to be precisely positioned and moved to different experimental areas for operation as needed. The coordination of the electric guide rail 2 302 and the electric guide rail 3 304 provides multi-directional flexibility, enabling the equipment to automatically adjust its position during the experiment, ensuring the precise transmission and processing of the sample in each step.
[0041] Please see the attached Figure 1 , Attachment Figure 3 and attached Figure 7 The remaining mobile components 3 are all connected to the experimental addition component 5, the experimental addition component 5 includes a delivery pump 501, and the delivery pump 501 is installed on the front side of the mobile seat four 305. The number of the remaining mobile components 3 matches the number of the delivery pumps 501. The input end of the delivery pump 501 is fixedly connected to the input pipe 502, and the output end of the delivery pump 501 is fixedly connected to the delivery pipe 503. The top of the mounting frame 1 is sequentially provided with an antibody tank 504, a magnetic bead tank 505, a washing tank 506, and an elution tank 507 from front to back, and the tops of multiple input pipes 502 are respectively connected to the inside of the antibody tank 504, the magnetic bead tank 505, the washing tank 506, and the elution tank 507.
[0042] Specifically, the remaining mobile components 3 are all connected to the experimental addition component 5, and the experimental addition component 5 is responsible for accurately adding various reagents during the processing. The experimental addition component 5 includes a delivery pump 501, which is installed on the front side of the mobile seat 29 305 to ensure that the position of the delivery pump 501 is stable and convenient for subsequent operations. The number of the remaining mobile components 3 matches the number of delivery pumps 501, and each delivery pump 501 is equipped with a corresponding input pipe 502 and a delivery pipe 503 to ensure the accurate transmission of liquid. The input end of the delivery pump 501 is fixedly connected with an input pipe 502, which is used to transport various reagents from a storage tank to the delivery pump 501. The output end is fixedly connected with a delivery pipe 503, which then transports the reagents to the sample processing module to ensure the accurate placement of the reagents. The top of the mounting frame 1 is sequentially provided with an antibody tank 504, a magnetic bead tank 505, a washing tank 506, and an elution tank 507 from front to back. These tanks store various liquids and reagents that need to be used during the experiment. The top ends of the multiple input tubes 502 are respectively connected to the interior of the antibody tank 504 , the magnetic bead tank 505 , the washing tank 506 , and the elution tank 507 , so that each reagent can be accurately delivered to the desired location through the corresponding input tube 502 .
[0043] Please see the attached Figure 1 and attached Figure 8 Multiple sensors 12 are installed on the left side of the interior of the mounting frame 1. These sensors 12 transmit the collected data to the central control system. The central control system includes: an acquisition module, which is responsible for collecting real-time data from the various sensors 12 in the device and transmitting it to the central control system for further processing; an analysis module, which processes and analyzes the data obtained from the acquisition module to determine whether the device is in normal working order and generates control instructions based on the analysis results to adjust the device's operation; and a driver module, which is responsible for receiving control instructions from the analysis module and driving the various components of the device to perform corresponding operations based on these instructions.
[0044] Specifically, multiple sensors 12 are installed on the left side of the mounting frame 1. These sensors 12 are responsible for collecting real-time data on key parameters of the equipment (such as temperature, liquid level, displacement, etc.) and transmitting this data to the central control system. The central control system includes an acquisition module, an analysis module, and a drive module.
[0045] The acquisition module is responsible for collecting real-time data from the various sensors 12 within the device, monitoring the device's operating status in real time, and transmitting this data to the central control system for further processing. The analysis module, upon receiving the data transmitted by the acquisition module, processes and analyzes it to determine whether the device is operating normally, such as whether the temperature meets predetermined requirements, whether the liquid level is normal, and whether there are any abnormalities in the device. Based on the analysis results, the analysis module generates control instructions to adjust the device's operation and ensure that the device is always in optimal working condition. The driver module is responsible for receiving control instructions from the analysis module and, based on these instructions, driving the various components of the device to perform corresponding operations, such as adjusting the temperature, adjusting the liquid delivery flow, and controlling the movement of the robotic arm or gripper.
[0046] Working Principle: The device begins operation with sample input. Sample tubes 206 or centrifuge tubes 207 are placed on the transport assembly 2, which comprises a motorized guide rail 201 and multiple movable bases. The motorized guide rail 201 transports the sample tubes 206 or centrifuge tubes 207 along a horizontal path to the experimental processing area. The sample tubes 206 are precisely secured to the fixed frame 204 by motorized grippers 205, ensuring a stable position during processing.
[0047] Secondly, the sample undergoes crushing, immune reaction and washing. At this stage, the mobile component 3 transfers the sample to different processing modules in sequence through a series of electric guide rails and mobile seats such as electric guide rail 2 302, mobile seat 3 303, and mobile seat 4 305. The ultrasonic crusher 4 on the front side crushes the cells in the sample through its high-frequency vibration, releasing the target protein. The ultrasonic crusher 4 is installed on the outside of the mobile seat 4 305, which can accurately locate and operate stably. After the crushing is completed, the sample will continue to be sent to the immune response module through the conveying component 2. At this time, the reagents in the antibody tank 504, magnetic bead tank 505, washing tank 506 and elution tank 507 are transported to the sample for reaction. The delivery pump 501 adds these reagents to the sample in sequence through the input pipe 502 to ensure that the reagents in each step are added on time and fully react with the target protein. The delivery process of the washing solution and eluent is also controlled by the delivery pump 501, which ensures the effectiveness of the washing and elution processes through precise flow control.
[0048] Then, after the immune reaction and magnetic bead binding, the sample enters the magnetic rack 9. At this time, the antibody-protein complex on the surface of the magnetic beads is magnetically attracted, isolating the target protein. Unbound impurities and excess solution are removed by mechanical extraction 7, further removing nonspecifically bound proteins and impurities. Next, the target protein is eluted from the magnetic beads using an eluent and transferred to a centrifuge tube 207 for collection.
[0049] Finally, the eluted target protein is transferred to centrifuge 10 for centrifugation to remove impurities from the solution and concentrate the target protein. At this point, the device uses mechanical grippers 6 to move centrifuge tube 207 to centrifuge 10 for processing. Throughout the entire process, the device's central control system monitors key parameters such as temperature and liquid level in real time through sensors 12 to ensure that each operation step is carried out under optimal conditions. If the temperature or other parameters are abnormal, the control system will automatically adjust the operating status of the relevant components to ensure the smooth progress of the experimental process.
[0050] While embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions, and variations may be made to these embodiments without departing from the principles and spirit of the invention, and that the scope of the invention is defined by the appended claims and their equivalents.
Claims
1. A rapid protein immunoprecipitation sample processing device, comprising a mounting frame (1), characterized in that: The interior of the mounting frame (1) is provided with a conveying component (2), the upper side of the mounting frame (1) is provided with a plurality of moving components (3), the front side of the moving component (3) is connected to an ultrasonic crusher (4), and the remaining moving components (3) are all connected to an experimental addition component (5), a mechanical clamp (6) is installed on the right side of the interior of the mounting frame (1), a mechanical liquid extraction device (7) is installed on the left side of the interior of the mounting frame (1), a shaking table (8) is installed on the front side of the interior of the mounting frame (1), a magnetic frame (9) is installed on the right side of the interior of the mounting frame (1), a centrifuge (10) is installed on the rear side of the interior of the mounting frame (1), and a waste liquid placement box (11) is installed on the rear side of the mechanical liquid extraction device (7); The conveying assembly (2) includes an electric guide rail (201), a movable seat (202) is installed on the front side of the electric guide rail (201), and a movable seat (203) is installed on the rear side of the electric guide rail (201). The upper parts of the movable seat (202) and the movable seat (203) are fixedly connected to a fixed frame (204), and a plurality of electric clamps (205) are installed on the outside of the fixed frame (204). A sample tube (206) is placed on the upper side of the fixed frame (204) on the front side, and a centrifuge tube (207) is placed on the upper side of the fixed frame (204) on the rear side.
2. The rapid protein immunoprecipitation sample processing device according to claim 1, characterized in that: The moving assembly (3) includes a fixed plate (301), an electric guide rail 2 (302) is installed on the front side of the fixed plate (301), a moving seat 3 (303) is installed on the outside of the electric guide rail 2 (302), an electric guide rail 3 (304) is installed on the front side of the moving seat 3 (303), and a moving seat 4 (305) is installed on the outside of the electric guide rail 3 (304).
3. The rapid protein immunoprecipitation sample processing device according to claim 2, characterized in that: The experimental addition component (5) includes a delivery pump (501), which is installed on the front side of the movable seat four (305), the input end of the delivery pump (501) is fixedly connected to the input pipe (502), and the output end of the delivery pump (501) is fixedly connected to the delivery pipe (503), and the top of the mounting frame (1) is provided with an antibody tank (504), a magnetic bead tank (505), a washing tank (506), and an elution tank (507) in sequence from front to back.
4. The rapid protein immunoprecipitation sample processing device according to claim 1, characterized in that: The electric clamp (205) at the front side limits and fixes the sample tube (206), and the electric clamp (205) at the rear side limits and fixes the centrifuge tube (207).
5. The rapid protein immunoprecipitation sample processing device according to claim 3, characterized in that: The ultrasonic disruptor (4) is installed outside the movable seat four (305) in the front movable assembly (3), and the number of the remaining movable assemblies (3) matches the number of the delivery pumps (501). The top ends of the multiple input tubes (502) are respectively connected to the inside of the antibody tank (504), the magnetic bead tank (505), the washing tank (506), and the elution tank (507).
6. The rapid protein immunoprecipitation sample processing device according to claim 1, characterized in that: A plurality of sensors (12) are installed on the left side of the interior of the mounting frame (1), and the sensors (12) transmit collected data to a central control system.
7. The rapid protein immunoprecipitation sample processing device according to claim 1, characterized in that: Temperature control ports (13) are provided on both the left and right sides of the interior of the mounting frame (1), and the temperature control ports (13) are used to control the internal temperature of the mounting frame (1).
8. The rapid protein immunoprecipitation sample processing device according to claim 1, characterized in that: Heat dissipation openings (14) are provided on both the left and right sides of the exterior of the mounting frame (1), and a controller (15) is installed on the right side of the exterior of the mounting frame (1).
9. The rapid protein immunoprecipitation sample processing device according to claim 1, characterized in that: A placement rack (16) is installed on the left side of the exterior of the mounting rack (1), and the placement rack (16) is used to place garbage generated by the experiment.
10. The rapid protein immunoprecipitation sample processing device according to claim 6, characterized in that: The central control system includes: Acquisition module: The acquisition module is responsible for collecting real-time data from various sensors (12) in the device and transmitting it to the central control system for further processing; Analysis module: The analysis module processes and analyzes the data obtained from the acquisition module to determine whether the equipment is in normal working condition, and generates control instructions based on the analysis results to adjust the operation of the equipment; Driver module: The driver module is responsible for receiving control instructions issued by the analysis module and driving the various components of the device to perform corresponding operations according to these instructions.