Matrine-bacterial cellulose gel prepared through in-situ growth, preparation method of matrine-bacterial cellulose gel, matrine-bacterial cellulose sustained-release particles and application of matrine-bacterial cellulose sustained-release particles

Maltine was embedded in the bacterial nanocellulose structure by in situ growth method to prepare a matrine-bacterial cellulose gel, which solved the problem of multiple drug administration in the prior art, and achieved long-term insecticidal and cost-reducing effects.

CN120477199APending Publication Date: 2025-08-15JIAXING UNIV
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Patent Information

Application Number
CN202510409010.9
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-04-02
Publication Date
2025-08-15

AI Technical Summary

Technical Problem

The existing malphurica pesticide dosage forms have to be applied frequently multiple times due to poor stability and short half-life, which increases the workload and cost, and is seriously polluted and has poor market competitiveness.

Method used

Maltine was embedded in the three-dimensional spatial structure of bacterial nanocellulose by in situ growth method, and the Maltine-bacterial cellulose gel was prepared, and the sustained release and antioxidant properties of bacterial cellulose were used to achieve the long-term and long-lasting insecticidal effect of Maltine.

Benefits of technology

It has achieved the long-term and long-lasting insecticidal effect of matrine, reducing the number of medications, reducing workload and cost, and improving market competitiveness.

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Abstract

The invention provides a method for preparing sophocarpidine-bacterial cellulose gel through in-situ growth, which comprises the following steps: crushing fresh yellow wine vinasse by using a stirrer, adding water, boiling, cooling to 60 DEG C, then adding glucoamylase, fully and uniformly stirring, carrying out enzymolysis, and filtering by using gauze after the enzymolysis is finished to obtain vinasse enzymatic hydrolysate; adding cane sugar and black tea into water, heating to boil, cooling to room temperature, filtering, taking filtrate, adding the wall-broken hibiscus manihot flavone extract into the filtrate, and stirring for dissolving to obtain a fermentation aid; taking 200ml of vinasse enzymatic hydrolysate, adjusting the pH value to 4, then adding a fermentation auxiliary agent and sophocarpidine, inoculating acetobacter gluconoxylinum, standing and culturing for 7 days at the constant temperature of 25 DEG C, and then washing and draining to obtain the sophocarpidine-bacterial cellulose gel. Meanwhile, the invention further provides the prepared matrine-bacterial cellulose gel, sustained-release particles and application of the matrine-bacterial cellulose gel and the sustained-release particles. The problems that in the prior art, the workload is large and the cost is high due to the fact that matrine needs to be frequently applied many times are solved.
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