Mouse head fixing device and fixing method thereof

By designing a mouse head fixing device, using the combination of threaded adjustment rod and threaded rod, combined with pressure sensor and LED indicator light, stable fixation and accurate nose drop of mouse head are achieved, solving the problems of unstable fixing effect and low safety in the prior art, and improving operating efficiency and safety.

CN120477997APending Publication Date: 2025-08-15NINGXIA MEDICAL UNIV
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Patent Information

Application Number
CN202510841737.4
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-06-23
Publication Date
2025-08-15

AI Technical Summary

Technical Problem

The existing fixation methods of mice have unstable fixation effects and cannot accurately drip the nose; multiple people need to cooperate to complete the nasal drip, which has low operating efficiency and safety; excessive constraints or improper operation can easily cause stress or injury in mice.

Method used

A mouse head fixing device is designed, including a base plate, support column, vertical rod, lower pressure plate, upper pressure plate, telescopic rod, snap ring and other components. Through the cooperation of the threaded adjustment rod and the threaded rod, stable fixation of the mouse head is achieved, and a pressure sensor and LED indicator light are equipped to monitor and indicate the appropriate fixing force in real time.

Benefits of technology

It realizes efficient and safe single-person operation, improves the accuracy of nose drops, reduces the risk of stress and injury in mice, and improves the safety of biological experiments.

✦ Generated by Eureka AI based on patent content.

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Abstract

The invention discloses a mouse head fixing device and a fixing method thereof. A lower pressing plate is fixed to a vertical rod, an upper pressing plate is rotationally installed at the lower end of a threaded adjusting rod, a buckle ring is installed on a telescopic rod, an adjusting hole is formed in a supporting stand column, a connecting block is rotationally installed at the lower end of a vertical threaded rod, and a side pressing plate is rotationally installed at the front end of a horizontal threaded rod. When the mouse fixing device is used, a mouse can be placed on the bottom plate, the head of the mouse is obliquely located on the lower pressing plate, the threaded adjusting rod is screwed to drive the upper pressing plate to move downwards to fix the mouse head from the top, the vertical threaded rod is screwed to enable the side pressing plate to be at a proper height, and the horizontal threaded rod is screwed to drive the side pressing plate to move to fix the mouse head from the side face, so that the fixing stability can be improved; after the telescopic rod slides to a proper position, the telescopic rod is adjusted to enable the buckle ring to be located at a proper height, the nose tip of the mouse is fixed through the buckle ring, and the nasal dripping accuracy can be improved. Through cooperation of a pressure sensor and an LED indicating lamp, an operator can be accurately prompted that the current installation force is within a proper range.
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Description

Technical Field

[0001] The present invention relates to the technical field of animal experiments, and in particular to a mouse head fixing device and a fixing method thereof. Background Art

[0002] In biomedical research, mice are one of the most common experimental animals. This is especially true in pathology studies, drug development, and neurological research, where nasal administration (nasal drop testing) is often required. However, mice are naturally highly alert and easily startled. This can lead to stress during experiments, causing them to struggle violently and even attack the experimenter, resulting in drug delivery failures, data distortion, and even injuries.

[0003] The main fixation methods currently used in laboratories are: manual fixation: pinch the skin on the back of the mouse's neck with the left hand, and perform nasal drip with the right hand. This method is highly dependent on operating experience and techniques. If the force is inappropriate, it will cause suffocation and death of the mouse, and it cannot completely prevent the mouse's head from shaking, making it difficult to drip medicine, or inaccurate drug administration, or even bite the experimenter. Simple restraint devices, such as plastic cone barrels, cannot completely fix the mouse. They only restrict the mouse's body movement, but the head can still move freely. The mouse still needs to be manually fixed during the nasal drip operation, and the pressure cannot be accurately controlled. There is also a risk of excessive restraint, which can easily lead to breathing difficulties, injuries, and other problems in the mouse; anesthesia fixation, although the anesthetized mouse will struggle less, it is easy to affect the accuracy of the experimental data after anesthesia, and frequent anesthesia is also likely to increase the mortality rate of mice.

[0004] Therefore, the current methods of fixing mice have the following main limitations: the fixation effect is unstable and accurate nasal drops cannot be performed; the operation efficiency is low and multiple people need to work together to complete the nasal drops; the safety is low and the bite force of mice is very strong, so there is a risk of being bitten by bare hands; excessive restraint or improper operation can easily cause stress or injury to mice. Summary of the Invention

[0005] The purpose of the present application is to provide a mouse head fixation device and a fixation method thereof, so as to solve the problems of unstable fixation effect and inability to accurately drip nose; requiring multiple people to cooperate to complete the drip nose, low operating efficiency and safety, and excessive restraint or improper operation, which can easily cause stress or injury to mice.

[0006] To solve the above technical problems, the present application provides a mouse head fixing device, comprising: The top end of the vertical rod is screwed onto the support post, and the bottom end of the horizontal threaded rod is rotatably mounted on the support post. The lower pressure plate is integrated with a pressure sensor and an LED indicator light communicating with the pressure sensor. A power supply battery and a power switch are installed on the base plate through an installation slot. The power supply battery is electrically connected to the pressure sensor and the LED indicator light through a power supply wire arranged in the vertical rod.

[0007] As a preferred embodiment, a mouse head fixing device is provided, wherein a slide groove is provided on the base plate, a slider is slidably provided in the slide groove, the telescopic rod is fixed on the slider, a threaded push rod is screwed on one side of the base plate, one end of the threaded push rod extends into the slide groove and is rotatably connected to one side of the slider.

[0008] What needs to be explained in detail in the scheme is a mouse head fixing device, the telescopic rod includes a fixed rod fixed on the slider and an adjusting rod inserted in the fixed rod, the fixed rod is provided with a plurality of first mounting holes, the adjusting rod is provided with a second mounting hole, and the fixed rod and the adjusting rod are fixed by pins installed in the first mounting holes and the second mounting holes.

[0009] As a preferred embodiment, a mouse head fixing device is provided, wherein a clamping plate is provided at one end of the buckle ring, and a plurality of clamping strips corresponding to the clamping plate are fixed on the outside of the other end.

[0010] As a preferred embodiment, a mouse head fixing device, the upper pressing plate, the lower pressing plate and the side pressing plates are all made of stainless steel plates and the inner sides thereof are arc-shaped.

[0011] What needs to be explained in detail in the solution is a mouse head fixing device, wherein the inner sides of the upper pressing plate, the lower pressing plate and the side pressing plates are all bonded with medical silicone pads.

[0012] As a preferred embodiment, in a mouse head fixing device, operating handles are fixed to the outer ends of the threaded adjustment rod, the vertical threaded rod, and the horizontal threaded rod.

[0013] As a preferred embodiment, a mouse head fixing device, the bottom plate is an acrylic bottom plate.

[0014] To solve the above technical problems, the present application further provides a method for fixing a mouse head, based on any one of the above mouse head fixing devices, comprising: Place the mouse on the bottom plate with its head tilted upward on the lower pressing plate; Twist the threaded adjustment lever to move the upper pressure plate downward to secure the mouse's head from the top. Simultaneously, press the power switch to monitor the pressure applied to the mouse's lower jaw by the upper pressure plate through the pressure sensor in real time. When the LED indicator lights up, it indicates that the pressure value has reached the preset single-point threshold. Twisting the vertical threaded rod drives the connecting block to move in the adjustment hole, which in turn drives the horizontal threaded rod to move so that the side pressure plate is at the appropriate height corresponding to the mouse head; Twist the horizontal threaded rod to move the side pressure plate to fix the mouse's head from the side; After sliding the telescopic rod to the appropriate position according to the mouse's body size, adjust the telescopic rod so that the buckle ring is at the appropriate height corresponding to the mouse's nose, and fix the mouse's nose with the buckle ring.

[0015] Compared with the prior art, the mouse head fixing device provided by the present invention comprises a base plate, a supporting column arranged oppositely and a vertical rod located between the supporting columns are fixed on the base plate, a lower pressure plate is fixed on the vertical rod, a mounting rod is fixed on the supporting column, a threaded adjustment rod is screwed on the mounting rod, an upper pressure plate corresponding to the lower pressure plate is rotatably mounted on the lower end of the threaded adjustment rod, a telescopic rod corresponding to the vertical rod is slidably arranged on the base plate, a snap ring is mounted on the telescopic rod, an adjustment hole is provided on the supporting column, a vertical threaded rod is screwed on the mounting rod, the lower end of the vertical threaded rod extends into the adjustment hole and is rotatably mounted with a connecting block, a horizontal threaded rod is screwed on the connecting block, and the horizontal threaded rod The ends of the rod extend to both sides of the support column through adjustment holes. The front end of the horizontal threaded rod is rotatably installed with side pressure plates corresponding to the lower pressure plate. When in use, the mouse can be placed on the bottom plate with its head tilted on the lower pressure plate. Screwing the threaded adjustment rod drives the upper pressure plate downward to fix the mouse's head from the top. After screwing the vertical threaded rod to adjust the side pressure plates to the appropriate height, screwing the horizontal threaded rod drives the side pressure plates to move and fix the mouse's head from the side, which can improve the fixation stability. Then, after sliding the telescopic rod to the appropriate position according to the mouse's body shape, adjust the telescopic rod so that the snap ring is at the appropriate height. The snap ring is used to fix the mouse's nose, which can improve the accuracy of nasal drip. Moreover, using this fixing device, the entire nasal drip operation can be completed by one person, which is efficient and safe.

[0016] The lower pressing plate is integrated with a pressure sensor and an LED indicator light that is connected to the pressure sensor for communication. A power supply battery and a power switch are installed on the bottom plate through a mounting groove. The power supply battery is electrically connected to the pressure sensor and the LED indicator light through a power supply wire arranged in a vertical rod. The pressure sensor can monitor the pressure applied to the mouse's mandible by the upper pressing plate in real time. When the pressure value reaches a preset single-point threshold, the LED indicator light immediately lights up, providing a clear visual warning signal, accurately prompting the operator that the current installation force is within the appropriate range, avoiding excessive restraint of the mouse, causing stress or injury to the mouse. In addition, the present application provides a method for fixing the mouse head, the effect of which is as above. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] In order to more clearly illustrate the technical solution of the present application, the following is a brief introduction to the drawings required for use in the embodiments. Obviously, for ordinary technicians in this field, other drawings can be obtained based on these drawings without inventiveness.

[0018] Figure 1 A schematic structural diagram of a mouse head fixing device provided in an embodiment of the present application; Figure 2 A schematic diagram of a telescopic rod structure from another angle provided in an embodiment of the present application; Figure 3 A schematic diagram of a telescopic rod structure provided in an embodiment of the present application; Figure 4 A schematic diagram of a snap ring structure provided in an embodiment of the present application; Figure 5 A schematic diagram of a base plate structure provided in an embodiment of the present application; Figure 6 A schematic diagram of the connection structure of a connecting block, a vertical threaded rod, and a horizontal threaded rod provided in an embodiment of the present application; In the figure: 1. Base plate; 2. Support column; 3. Vertical rod; 4. Lower pressure plate; 5. Mounting rod; 6. Threaded adjustment rod; 7. Upper pressure plate; 8. Telescopic rod; 9. Snap ring; 90. Card slot; 10. Adjustment hole; 11. Vertical threaded rod; 12. Connecting block; 13. Horizontal threaded rod; 14. Side pressure plate; 15. LED indicator; 16. Power switch; 17. Slide groove; 18. Slider; 19. Fixed rod; 20. Adjustment rod; 21. First mounting hole; 22. Latch; 23. Card plate; 24. Card strip; 25. Operating handle; 26. Threaded push rod. DETAILED DESCRIPTION

[0019] In order to enable people skilled in the art to better understand the technical solutions in the present application, the technical solutions in the embodiments of the present application will be clearly and completely described below in conjunction with the accompanying drawings.

[0020] The core of this application is to provide a mouse head fixation device and a fixation method thereof, which solves the problems of unstable fixation effect and inability to accurately drip nose; requiring multiple people to work together to complete the drip nose, low operating efficiency and safety, and excessive restraint or improper operation, which can easily cause stress or injury to mice.

[0021] Figure 1 A schematic structural diagram of a mouse head fixing device provided in an embodiment of the present application; Figure 2 A schematic diagram of a telescopic rod structure from another angle provided in an embodiment of the present application; Figure 3 A schematic diagram of a telescopic rod structure provided in an embodiment of the present application; Figure 4 A schematic diagram of a snap ring structure provided in an embodiment of the present application; Figure 5 A schematic diagram of a base plate structure provided in an embodiment of the present application; Figure 6 Schematic diagram of the connection structure of a connecting block, a vertical threaded rod and a horizontal threaded rod provided in an embodiment of the present application; see Figures 1 to 6 shown.

[0022] Example 1 A mouse head fixing device includes a base plate 1, which is made of a 50mm×40mm×3mm acrylic plate. Support columns 2 and vertical rods 3 are fixed to the base plate 1, which are arranged opposite each other. The support columns 2 are made of an aluminum alloy column with a diameter of 6mm and a height of 30mm. The vertical rod 3 is located between the two support columns 2. A lower pressure plate 4 is fixed to the vertical rod 3, and a mounting rod 5 is fixed to the support columns 2. The mounting rod 5 is screwed with a threaded adjustment rod 6. The lower end of the threaded adjustment rod 6 is rotatably mounted with an upper pressure plate 7. The upper pressure plate 7 and the lower pressure plate 4 correspond to each other in the vertical direction. During use, the mouse can be pressed and placed on the base plate 1 so that its lower jaw is located on the lower pressure plate 4 and the head is in a tilted upward state. Screwing the operating threaded adjustment rod 6 can drive the upper pressure plate 7 to move downward to fix the mouse's head from the top. The lower pressure plate 4 is integrated with a pressure sensor and an LED indicator light 15 that is connected to the pressure sensor. A power supply battery and a power switch 16 are installed on the base plate 1 through an installation groove. The power supply battery is electrically connected to the pressure sensor and the LED indicator light 15 through a power supply wire set in the vertical rod 3. In the actual design process, a comparator is also integrated in the lower pressure plate 4, and the comparator is connected to the power supply battery through a power supply wire. The installation groove, pressure sensor, comparator and power supply battery are not shown in the figure. During installation, a small hole for installing the LED indicator light 15 is provided on the lower pressure plate 4. The front part of the LED indicator light 15 is exposed on the outside of the lower pressure plate 4 and covered with a transparent acrylic shell, so that it is easy to check whether the LED indicator light 15 is on in time, and then determine whether the pressure value applied meets the standard. During this process, the pressure sensor detects the pressure applied by the upper platen 7. When the pressure reaches a preset single-point threshold (for example, 100g ± 10g, the specific threshold can be set according to experimental requirements), the comparator is triggered, and the LED indicator 15 immediately illuminates red, providing a clear visual warning signal, accurately reminding the operator that the current installation force is within the appropriate range. The power supply battery powers the pressure sensor, LED indicator, and comparator. The battery is installed in the mounting slot, significantly improving the convenience of battery replacement, supporting the fixture's long-term continuous operation and multiple cycles.

[0023] A telescopic rod 8 corresponding to the vertical rod 3 is slidingly provided on the base plate 1. After installation, the telescopic rod 8 and the vertical rod 3 correspond to each other in the horizontal direction. The usable height of the vertical rod 3 is lower than the usable height of the telescopic rod 8. The telescopic rod 8 can slide closer to or away from the vertical rod 3 on the base plate 1. A snap ring 9 is installed on the telescopic rod 8. After the telescopic rod 8 moves into place, the telescopic rod 8 can be controlled to extend and retract to drive the snap ring 9 to be at a suitable height position. The nose of the mouse is fixed by the snap ring 9, which facilitates the nasal drip operation on the mouse. An adjustment hole 10 is provided on the support column 2, and a vertical threaded rod 11 is screwed on the mounting rod 5. The lower end of the vertical threaded rod 11 extends into the adjustment hole 10 and is rotatably installed with a connecting block 12. After installation, the connecting block 12 is located in the adjustment hole 10, and a horizontal threaded rod 13 is screwed on the connecting block 12. Both ends of the horizontal threaded rod 13 extend to both sides of the support column 2 through the adjustment hole 10, and a side pressure plate 14 corresponding to the lower pressure plate 4 is rotatably installed at the front end of the horizontal threaded rod 13; the upper pressure plate 7, the lower pressure plate 4 and the side pressure plate 14 are all It is made of stainless steel sheets with a thickness of 0.3mm, a size of 25mm×5mm, and a hardness of HV300. When in use, the vertical threaded rod 11 can be used to drive the connecting block 12 to move up and down in the adjustment hole 10, thereby adjusting the height of the side pressure plate 14. Then, the horizontal threaded rod 13 is screwed to drive the side pressure plate 14 to move in the horizontal direction. During the movement, the side pressure plate 14 rotates accordingly. After moving into place, the side pressure plate 14 can be manually rotated to the appropriate direction to fix the mouse's head from both sides. This structural design can realize the mouse head fixing operation for mice of different sizes. The rotational connection between the side pressure plate 14 and the front end of the horizontal threaded rod 13 needs to be based on the principle that it cannot rotate freely when not subjected to external force.

[0024] Example 2 Based on Example 1, a mouse head fixing device is provided. To achieve the sliding installation of the telescopic rod 8, preferably, a slide groove 17 is provided on the base plate 1. A slider 18 is slidably provided in the slide groove 17. The telescopic rod 8 is fixed to the slider 18. A threaded push rod 26 is screwed onto one side of the base plate 1. One end of the threaded push rod 26 extends into the slide groove 17 and is rotatably connected to one side of the slider 18. During use, the threaded push rod 26 can be screwed to move the slider 18, thereby driving the telescopic rod 8 toward or away from the vertical rod 3.

[0025] On the basis of Example 2, a mouse head fixing device is provided. In order to facilitate the adjustment of the height of the telescopic rod 8, preferably, the telescopic rod 8 includes a fixing rod 19 fixed on the slider 18 and an adjusting rod 20 inserted in the fixing rod 19. The fixing rod 19 is provided with a plurality of first mounting holes 21, and the adjusting rod 20 is provided with a second mounting hole. When in use, the insertion depth of the adjusting rod 20 in the fixing rod 19 can be adjusted according to actual conditions, thereby achieving the adjustment of the height of the telescopic rod 8. After adjustment, the fixing rod 19 and the adjusting rod 20 can be fixed by the pins 22 installed in the first mounting holes 21 and the second mounting holes.

[0026] On the basis of Example 1, a mouse head fixing device is provided. In order to fix the mouse head, preferably, a clamping plate 23 is provided at one end of a snap ring 9, and a plurality of clamping strips 24 corresponding to the clamping plate 23 are fixed on the outside of the other end. The snap ring 9 can be made of a deformable plastic material. When in use, the clamping plate 23 is clamped into the clamping groove 90 formed by the clamping strip 24 and the snap ring 9 according to the size of the nose tip, so that the snap ring 9 fits tightly on the nose tip to fix the nose tip.

[0027] Based on Example 1, a mouse head fixing device is provided. Preferably, the upper pressing plate 7, the lower pressing plate 4, and the side pressing plates 14 are all made of stainless steel plates, and their inner sides are curved. This design can improve the fit of the upper pressing plate 7, the lower pressing plate 4, and the side pressing plates 14 to the contour of the mouse head.

[0028] In this embodiment, a mouse head fixing device is provided. In order to prevent the mouse head from being crushed or damaged, preferably, medical silicone pads are bonded to the inner sides of the upper pressing plate 7, the lower pressing plate 4 and the side pressing plate 14. The medical silicone pads are not shown in the figure.

[0029] Based on Example 1, a mouse head fixing device is provided. To facilitate the screwing operation of the threaded adjustment rod 6, the vertical threaded rod 11, and the horizontal threaded rod 13, an operating handle 25 is preferably fixed to the outer end of the threaded adjustment rod 6, the vertical threaded rod 11, and the horizontal threaded rod 13. When in use, the operating handle 25 can be used to screw the rods.

[0030] The present invention provides a mouse head fixing device, including a base plate 1, on which are fixed relatively arranged support columns 2 and a vertical rod 3 located between the support columns 2, a lower pressure plate 4 being fixed on the vertical rod 3, and a mounting rod 5 being fixed on the support column 2. A threaded adjustment rod 6 is screwed on the mounting rod 5, and an upper pressure plate 7 corresponding to the lower pressure plate 4 is rotatably mounted on the lower end of the threaded adjustment rod 6, a telescopic rod 8 corresponding to the vertical rod 3 is slidably provided on the base plate 1, a snap ring 9 is mounted on the telescopic rod 8, an adjustment hole 10 is provided on the support column 2, a vertical threaded rod 11 is screwed on the mounting rod 5, the lower end of the vertical threaded rod 11 extends into the adjustment hole 10 and is rotatably mounted with a connecting block 12, a horizontal threaded rod 13 is screwed on the connecting block 12, and the horizontal threaded rod 13 is screwed on the connecting block 12. The two ends of the threaded rod 13 extend to both sides of the support column 2 through the adjustment hole 10. The front end of the horizontal threaded rod 13 is rotatably mounted with a side pressure plate 14 corresponding to the lower pressure plate 4. When in use, the mouse can be placed on the bottom plate 1 so that its head is tilted and positioned on the lower pressure plate 4. The upper pressure plate 7 is moved downward by screwing the threaded adjustment rod 6 to fix the mouse's head from the top. After screwing the vertical threaded rod 11 to bring the side pressure plates 14 to a suitable height, the horizontal threaded rod 13 is screwed to move the side pressure plates 14 to fix the mouse's head from the side, thereby improving the stability of the fixation. Then, after sliding the telescopic rod 8 to a suitable position according to the size of the mouse, the telescopic rod 8 is adjusted so that the snap ring 9 is at an appropriate height. The mouse's nose is fixed by the snap ring 9 to improve the accuracy of the nasal drip. Moreover, with this fixing device, the entire nasal drip operation can be completed by one person, which is efficient and safe.

[0031] The lower pressing plate 4 is integrated with a pressure sensor and an LED indicator light 15 that communicates with the pressure sensor. A power supply battery and a power switch 16 are installed in a mounting slot on the base plate 1. The power supply battery is electrically connected to the pressure sensor and LED indicator light 15 via power supply wires set in the vertical rod 3. The pressure sensor can monitor the pressure applied to the mouse's lower jaw by the upper pressing plate 7 in real time. When the pressure value reaches a preset single-point threshold, the LED indicator light 15 immediately lights up, providing a clear visual warning signal, accurately reminding the operator that the current installation force is within the appropriate range, avoiding excessive restraint on the mouse, causing stress or injury to the mouse.

[0032] The above describes in detail an embodiment of a mouse head fixing device. Based on the mouse head fixing device described in the above embodiment, an embodiment of the present invention also provides a mouse head fixing method corresponding to the device. Since the embodiment of the method part corresponds to the embodiment of the device part, please refer to the description of the embodiment of the device part for the embodiment of the method part, and no further details will be given here.

[0033] A method for fixing a rat head, based on any one of the above-mentioned rat head fixing devices, comprises the following steps: S1: Place the mouse on the bottom plate with its head tilted upward on the lower pressing plate; S2: Turn the threaded adjustment lever to move the upper pressure plate downward to fix the mouse's head from the top. At the same time, press the power switch to monitor the pressure applied to the mouse's lower jaw by the upper pressure plate in real time through the pressure sensor. When the LED indicator lights up, it indicates that the pressure value has reached the preset single-point threshold. S3: Twist the vertical threaded rod to drive the connecting block to move in the adjustment hole, and then drive the horizontal threaded rod to move so that the side pressure plate is at the appropriate height corresponding to the mouse head; S4: Screw the horizontal threaded rod to move the side pressure plate to fix the mouse head from the side; S5: After sliding the telescopic rod to the appropriate position according to the size of the mouse, adjust the telescopic rod so that the buckle ring is at the appropriate height corresponding to the mouse's nose, and fix the mouse's nose with the buckle ring.

[0034] The mouse head fixation method provided by the present invention reduces the risk of people being bitten, reduces stress damage to mice, improves biosafety, and reduces irritation to mice. The nasal drop operation can be completed by one person throughout the process, which is efficient and safe.

[0035] Other embodiments of the present invention will readily occur to those skilled in the art after considering the specification and practicing the application disclosed herein. This application is intended to cover any variations, uses, or adaptations of the present invention that follow the general principles of this application and incorporate common knowledge or customary techniques in the art disclosed herein. The description and examples are to be considered merely as exemplary, and the true scope of this application is indicated by the claims.

[0036] It should be understood that the present application is not limited to the precise structure described above and shown in the drawings, and various modifications and changes can be made without departing from the scope thereof. The above-described embodiments of the present application do not constitute a limitation on the scope of protection of the present application.

Claims

1. A mouse head fixing device, characterized in that: include: A base plate (1) is fixed with supporting columns (2) arranged opposite to each other and vertical rods (3) located between the supporting columns (2), a lower pressure plate (4) is fixed on the vertical rod (3), a mounting rod (5) is fixed on the supporting columns (2), a threaded adjustment rod (6) is screwed on the mounting rod (5), an upper pressure plate (7) corresponding to the lower pressure plate (4) is rotatably mounted on the lower end of the threaded adjustment rod (6), a telescopic rod (8) corresponding to the vertical rod (3) is slidably mounted on the base plate (1), and a card is mounted on the telescopic rod (8). A buckle (9), an adjustment hole (10) is provided on the support column (2), a vertical threaded rod (11) is screwed on the mounting rod (5), the lower end of the vertical threaded rod (11) extends into the adjustment hole (10) and is rotatably mounted with a connecting block (12), a horizontal threaded rod (13) is screwed on the connecting block (12), both ends of the horizontal threaded rod (13) extend to both sides of the support column (2) through the adjustment hole (10), and a side pressure plate (14) corresponding to the lower pressure plate (4) is rotatably mounted on the front end of the horizontal threaded rod (13); A pressure sensor and an LED indicator light (15) in communication with the pressure sensor are integrated in the lower pressure plate (4); a power supply battery and a power switch (16) are installed on the base plate (1) through a mounting groove; the power supply battery is electrically connected to the pressure sensor and the LED indicator light (15) through a power supply wire arranged in the vertical rod (3).

2. The mouse head fixing device according to claim 1, characterized in that: A slide groove (17) is provided on the base plate (1), a slider (18) is slidably provided in the slide groove (17), the telescopic rod (8) is fixed on the slider (18), a threaded push rod (26) is screwed on one side of the base plate (1), one end of the threaded push rod (26) extends into the slide groove (17) and is rotatably connected to one side of the slider (18).

3. The mouse head fixing device according to claim 2, characterized in that: The telescopic rod (8) comprises a fixing rod (19) fixed on the slider (18) and an adjusting rod (20) inserted into the fixing rod (19); the fixing rod (19) is provided with a plurality of first mounting holes (21); the adjusting rod (20) is provided with a second mounting hole; the fixing rod (19) and the adjusting rod (20) are fixed by means of pins (22) installed in the first mounting holes (21) and the second mounting holes.

4. The mouse head fixing device according to claim 1, characterized in that: A clamping plate (23) is provided at one end of the buckle ring (9), and a plurality of clamping strips (24) corresponding to the clamping plate (23) are fixed on the outside of the other end.

5. The mouse head fixing device according to claim 1, characterized in that: The upper pressing plate (7), the lower pressing plate (4) and the side pressing plate (14) are all made of stainless steel plates and their inner sides are arranged in an arc shape.

6. The mouse head fixing device according to claim 5, characterized in that: Medical silicone pads are also bonded to the inner sides of the upper pressing plate (7), the lower pressing plate (4) and the side pressing plate (14).

7. The mouse head fixing device according to claim 1, characterized in that: An operating handle (25) is also fixed to the outer ends of the threaded adjustment rod (6), the vertical threaded rod (11), and the horizontal threaded rod (13).

8. The mouse head fixing device according to claim 1, characterized in that: The base plate (1) is an acrylic base plate.

9. A method for fixing a mouse head, based on the mouse head fixing device according to any one of claims 1 to 8, characterized in that: include: Place the mouse on the bottom plate with its head tilted upward on the lower pressing plate; Twist the threaded adjustment lever to move the upper pressure plate downward to secure the mouse's head from the top. Simultaneously, press the power switch to monitor the pressure applied to the mouse's lower jaw by the upper pressure plate through the pressure sensor in real time. When the LED indicator lights up, it indicates that the pressure value has reached the preset single-point threshold. Twisting the vertical threaded rod drives the connecting block to move in the adjustment hole, which in turn drives the horizontal threaded rod to move so that the side pressure plate is at the appropriate height corresponding to the mouse head; Twist the horizontal threaded rod to move the side pressure plate to fix the mouse's head from the side; After sliding the telescopic rod to the appropriate position according to the mouse's body size, adjust the telescopic rod so that the buckle ring is at the appropriate height corresponding to the mouse's nose, and fix the mouse's nose with the buckle ring.