Camellia oil composition for relieving dry, itching and red skin and preparation method thereof

Abstract

The invention relates to the technical field of soothing compositions, and discloses a camellia oil composition for soothing dry, itching and red skin and a preparation method of the camellia oil composition. 0.2 to 5 parts of natural vitamin E; 20 to 70 parts of glycerol; 0.1 to 5 parts of a nonionic emulsifier; 1 to 10 parts of water; in the camellia oil, the content of triterpene alcohol is greater than or equal to 1500mg / kg; the content of squalene is greater than or equal to 100mg / kg; the nonionic emulsifier is prepared from polyglycerol-6 stearate and glyceryl stearate. Camellia oil rich in triterpenol and squalene is adopted as a raw material, and the soothing effect can be effectively improved; meanwhile, the natural vitamin E is added, so that the active ingredients of triterpene alcohol and squalene in the camellia oil can be stabilized; and the camellia oil and the natural vitamin E are prepared into an intermediate which can be directly applied to water aqua, cream and cleaning products, and meanwhile, the stability of the products is improved.

Description

Technical Field

[0001] The present invention relates to the technical field of soothing compositions, and in particular to a camellia oil composition for soothing dry, itchy and red skin and a preparation method thereof. Background Art

[0002] Infant and child skin, as well as sensitive skin, has a more fragile skin barrier and is easily irritated. Even minor external stimuli can cause paroxysmal or periodic burning, flushing, stinging, itching, and tightness, with or without persistent erythema. Camellia oil is not only skin-friendly but also forms a moisture-locking protective layer on the skin's surface, reducing water loss. It also significantly boosts endogenous moisturizing factors, promoting epidermal hydration and increasing skin hydration. Furthermore, camellia oil contains a variety of anti-inflammatory active ingredients. Therefore, camellia oil is widely used in soothing products.

[0003] For example, patent CN105434193A discloses a baby camellia oil lotion and a preparation method thereof, which comprises the following components in parts by weight: component A: 0.5-4 parts of sucrose fatty acid ester, 67.9-92 parts of water, 3-8 parts of glycerol, component B: 0.1-0.3 parts of carbomer 940, component C: 0.1-0.5 parts of sodium dehydroacetate, component D: 3-10 parts of camellia oil, 1-5 parts of caprylic / decanoic acid triglyceride, 0.1-1 parts of palmitic acid, 0.1-3 parts of cetearyl alcohol, and 0.1-0.3 parts of vitamin E acetate.

[0004] However, traditional camellia oil has limited effect in soothing dry, itchy and red skin. Camellia oil is an oil-soluble raw material, and it is a technical challenge to directly add camellia oil to aqueous products and cleaning products. At the same time, camellia oil is a vegetable oil, and its use in cosmetic products is prone to oxidation, producing an oily odor and causing the color of the material to turn yellow. Maintaining product stability is also a technical challenge. Summary of the Invention

[0005] The present invention aims to overcome the above-mentioned problems existing in the application of camellia oil in cosmetic products in the prior art, and provides a camellia oil composition for soothing dry, itchy and red skin and a preparation method thereof. Camellia oil rich in triterpene alcohols and squalene is used as a raw material, which can effectively enhance the soothing effect. Natural vitamin E is added to stabilize the active ingredients triterpene alcohols and squalene in the camellia oil. The camellia oil and natural vitamin E are then prepared into an intermediate, which can be directly applied to aqueous solutions, creams and cleaning products, while improving the stability of the product.

[0006] In order to achieve the above object, the present invention adopts the following technical solutions: A camellia oil composition for relieving dry, itchy and red skin, comprising, by weight: Camellia oil: 0.5-30 parts; Natural vitamin E: 0.2~5 parts; Glycerin: 20~70 parts; Nonionic emulsifier: 0.1~5 parts; Water: 1-10 parts; The camellia oil has a triterpene alcohol content of ≥1500 mg / kg and a squalene content of ≥100 mg / kg. The nonionic emulsifier includes polyglyceryl-6 stearate and glyceryl stearate.

[0007] This invention uses camellia oil, rich in triterpenoids and squalene, as its primary ingredient, offering a stronger soothing effect (for dry, itchy, and red skin) than traditional camellia oil. Furthermore, the invention incorporates natural vitamin E into the camellia oil. Natural vitamin E has a strong antioxidant effect, stabilizing the triterpenoids and squalene in the oil, preventing oxidation that produces a greasy odor and yellowing, thereby maintaining product stability. Furthermore, natural vitamin E protects the skin from free radical damage, synergizing with camellia oil to combat irritation and damage caused by external stimuli, further enhancing the soothing effect of the composition.

[0008] The present invention also adds a nonionic emulsifier, glycerin, and water to form the camellia oil and natural vitamin E composition into an emulsion-like intermediate, which can be directly applied to aqueous solutions, creams, and cleansing products. This overcomes the difficulty of directly applying camellia oil and natural vitamin E in aqueous solutions and cleansing products, while also improving product stability. Furthermore, based on the properties of camellia oil, which is rich in triterpenoid alcohols and squalene, the present invention selects polyglyceryl-6 stearate and glyceryl stearate as nonionic emulsifiers, which enhance the emulsification effect and provide the composition with high stability.

[0009] Preferably, in the nonionic emulsifier, the mass ratio of polyglyceryl-6 stearate to glyceryl stearate is 1 to 1.5: 1. Polyglyceryl-6 stearate and glyceryl stearate have the best emulsification effect within this ratio range.

[0010] Preferably, the components include, by weight: Camellia oil: 5-20 parts; Natural vitamin E: 0.5~4 parts; Glycerin: 30~60 parts; Nonionic emulsifier: 0.5~4 parts; Water: 2~8 parts

[0011] The present invention also provides a method for preparing the camellia oil composition for relieving dry, itchy and red skin, comprising the following steps: (1) Preparation of camellia oil with a triterpene alcohol content of ≥1500 mg / kg and a squalene content of ≥100 mg / kg; (2) Heat and dissolve glycerin, water and non-ionic emulsifier completely and mix them evenly to form the water phase; (3) Heat and stir camellia oil and natural vitamin E to mix evenly as the oil phase; (4) The oil phase and the water phase are mixed evenly and homogenized under high pressure to obtain the camellia oil composition for relieving dry, itchy and red skin.

[0012] Preferably, the method for preparing camellia oil in step (1) comprises filtering and alkali-refining the crude camellia seed oil obtained by pressing camellia seeds, washing the oil with water, dehydrating the oil, and then decolorizing and deodorizing the oil under vacuum, and finally filtering the oil to obtain the camellia oil; the decolorization temperature is 70-80°C, and the deodorization temperature is 200-230°C. The present invention strictly limits the decolorization and deodorization temperatures when preparing camellia oil, reduces the conventional winterization step, retains more active ingredients, ensures that the contents of triterpene alcohols and squalene meet the requirements of the present invention, and has a strong effect of soothing dry, itchy and red skin.

[0013] Preferably, the heating and dissolving temperature in step (2) is 60-80°C.

[0014] Preferably, the heating and stirring temperature in step (3) is 55-75°C.

[0015] Preferably, the temperature of the oil phase and the water phase is maintained at 65-80°C when they are mixed in step (4).

[0016] Preferably, the speed during homogenization in step (4) is 2600-3000 rpm, the pressure is 110-140 MPa, and the homogenization time is 10-20 mins.

[0017] Preferably, in step (4), after homogenization, the mixture is stirred and cooled to below 45° C. to obtain the camellia oil composition for relieving dry, itchy and red skin.

[0018] Therefore, the present invention has the following beneficial effects: (1) Camellia oil, which is rich in triterpenoids and squalene, is used as the main ingredient. It has a stronger effect in soothing dry, itchy and red skin, and triterpenoids and squalene have a synergistic effect. (2) Camellia oil and natural vitamin E are compounded. Natural vitamin E can stabilize the active ingredients triterpenoid alcohol and squalene in camellia oil, and work together with camellia oil to resist irritation and damage to the skin caused by external stimuli; (3) Using polyglycerol-6 stearate and glyceryl stearate as non-ionic emulsifiers, camellia oil and natural vitamin E are made into emulsions, which can be directly applied to aqueous solutions, creams and cleaning products. This solves the difficulty of directly applying camellia oil and natural vitamin E in aqueous solutions and cleaning products, and at the same time improves the stability of the product. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 These are the test results of IL-1a expression in Examples 1 to 3 and Comparative Examples 1 to 3.

[0020] Figure 2 These are the test results of IL-8 expression in Examples 1 to 3 and Comparative Examples 1 to 3.

[0021] Figure 3 These are the test results of PGE2 expression in Examples 1 to 3 and Comparative Examples 1 to 3.

[0022] Figure 4 These are the test results of TSLP expression in Examples 1 to 3 and Comparative Examples 1 to 3.

[0023] Figure 5 These are the test results of FLG expression in Examples 1 to 3 and Comparative Examples 1 to 3.

[0024] Figure 6 These are photos of the shampoo prepared in Example 1 in its initial state and after storage for 3 months. (a) shows the initial state; (b) shows storage at -10°C for 3 months; (c) shows storage at 25°C for 3 months; and (d) shows storage at 45°C for 3 months.

[0025] Figure 7 These are actual pictures of the baby cream prepared in Example 2 in its initial state and after storage for 3 months; wherein, (a) is the initial state; (b) is stored at -10°C for 3 months; (c) is stored at 25°C for 3 months; and (d) is stored at 45°C for 3 months. DETAILED DESCRIPTION

[0026] The present invention will be further described below with reference to the accompanying drawings and specific embodiments.

[0027] In the present invention, unless otherwise specified, all equipment and raw materials can be purchased from the market or are commonly used in the industry. The methods in the following embodiments, unless otherwise specified, are all conventional methods in the art.

[0028] Overall embodiment: A camellia oil composition for relieving dry, itchy and red skin, comprising, by weight: Camellia oil: 0.5-30 parts; Natural vitamin E: 0.2~5 parts; Glycerin: 20~70 parts; Nonionic emulsifier: 0.1~5 parts; Water: 1-10 parts; The camellia oil has a triterpene alcohol content of ≥1500 mg / kg and a squalene content of ≥100 mg / kg. The nonionic emulsifier includes polyglyceryl-6 stearate and glyceryl stearate.

[0029] As a specific embodiment, in the nonionic emulsifier, the mass ratio of polyglycerol-6 stearate to glyceryl stearate is 1~1.5:1.

[0030] As a specific embodiment, the components include, by weight: Camellia oil: 5-20 parts; Natural vitamin E: 0.5~4 parts; Glycerin: 30~60 parts; Nonionic emulsifier: 0.5~4 parts; Water: 2~8 parts

[0031] The preparation method of the camellia oil composition for relieving dry, itchy and red skin comprises the following steps: (1) Preparation of camellia oil with a triterpene alcohol content of ≥1500 mg / kg and a squalene content of ≥100 mg / kg; (2) Heat and dissolve glycerin, water and non-ionic emulsifier completely and mix them evenly to form the water phase; (3) Heat and stir camellia oil and natural vitamin E to mix evenly as the oil phase; (4) The oil phase and the water phase are mixed evenly and homogenized under high pressure to obtain the camellia oil composition for relieving dry, itchy and red skin.

[0032] As a specific embodiment, the preparation method of camellia oil in step (1) is as follows: filtering and alkali-refining the crude camellia seed oil obtained by pressing camellia seeds, washing the oil with water, dehydrating the oil, and then decolorizing and deodorizing the oil under vacuum, and finally filtering the oil to obtain the camellia oil; the decolorization temperature is 70-80°C, and the deodorization temperature is 200-230°C.

[0033] As a specific implementation method, activated carbon and activated white clay with a mass ratio of 1:5~15 are used as decolorizers during decolorization, and the added amount of the decolorizer is 3~10% of the mass of the camellia seed crude oil; the vacuum degree during decolorization is controlled at -0.10~-0.098MPa, and the decolorization time is 10~50min.

[0034] As a specific implementation method, the vacuum degree during deodorization is controlled at -0.10~-0.098 MPa, and the deodorization time is 2~3 hours.

[0035] As a specific implementation method, a 300-400 mesh filter is used during filtration to remove impurities including colloids and debris, so that the impurity content is less than 0.2 wt%.

[0036] As a specific implementation method, the alkali refining process is: heating the filtered camellia seed crude oil to 65-70°C, adding a sodium hydroxide aqueous solution with a mass fraction of 10-15%, stirring until the soap particles are separated from the oil layer, and removing impurities and water in the lower layer after standing.

[0037] As a specific implementation method, the water washing process is as follows: heating the alkali-refined camellia seed crude oil to 75-80° C., washing it with a 5-10 wt % sodium chloride aqueous solution for 1-2 times, and then washing it with pure water for 2-3 times.

[0038] As a specific embodiment, the heating and dissolving temperature in step (2) is 60-80°C.

[0039] As a specific embodiment, the heating and stirring temperature in step (3) is 55~75°C.

[0040] As a specific embodiment, in step (4), the temperature of the oil phase and the water phase is maintained at 65-80°C when they are mixed.

[0041] As a specific implementation manner, the speed during homogenization in step (4) is 2600-3000 rpm, the pressure is 110-140 MPa, and the homogenization time is 10-20 mins.

[0042] As a specific embodiment, in step (4), after homogenization, the mixture is stirred and cooled to below 45° C. to obtain the camellia oil composition for relieving dry, itchy and red skin.

[0043] Example 1: A camellia oil composition for soothing dry, itchy and red skin, comprising, by weight, 5 parts of camellia oil; 0.5 parts of natural vitamin E; 30 parts of glycerin; 0.5 parts of a nonionic emulsifier; and 2 parts of water. The camellia oil contains 1550 mg / kg of triterpene alcohol and 108 mg / kg of squalene. The nonionic emulsifier is polyglyceryl-6 stearate and glyceryl stearate in a 1:1 mass ratio.

[0044] The preparation method of the camellia oil composition for relieving dry, itchy and red skin comprises the following steps: Preparation of camellia oil: A) Impurity Removal: Filter the cold-pressed camellia oil through a 400-mesh filter to remove impurities including colloids and debris, reducing the impurity content to less than 0.2 wt%; B) Alkali Refining: Take 100 kg by weight of filtered crude camellia oil, raise the temperature to 70°C, add 10% by mass sodium hydroxide aqueous solution, stir until soap particles separate from the oil layer, let it stand for 24 hours, and remove impurities and water in the lower layer by sedimentation separation to obtain alkali-refined crude camellia oil; C) Water washing: heating the alkali-refined camellia oil to 80°C, washing it once with a 5% sodium chloride aqueous solution and twice with pure water to obtain washed camellia oil; D) Dehydration: heating the washed camellia oil to 90°C and maintaining the temperature until the oil is completely dehydrated to obtain dehydrated camellia oil; E) Decolorization: When the temperature of the dehydrated crude camellia oil is controlled to 80°C and the vacuum degree is controlled at -0.10 to -0.098 MPa, a decolorizer (10% by weight of the crude camellia oil) is added. The decolorizer is a mixture of activated carbon and activated clay. The mass ratio of activated carbon to activated clay is 1:15. After decolorization for 40 minutes, the decolorized crude camellia oil is obtained. The color of the decolorized crude camellia oil is light yellow. F) Deodorization: heating the bleached crude camellia oil to 230°C and deodorizing for 3 hours under a vacuum degree controlled at -0.10 to -0.098 MPa to obtain deodorized camellia oil, and further filtering to obtain camellia oil; (2) Dissolve glycerin, water and nonionic emulsifier completely at 75°C and mix them evenly to form the aqueous phase; (3) Mix camellia oil and natural vitamin E at 57°C and stir to obtain the oil phase; (4) The oil phase and the water phase were mixed uniformly at 70° C. and homogenized under high pressure to obtain the camellia oil composition for relieving dry, itchy and red skin; the homogenization speed was 2700 rpm, the pressure was 120 MPa, and the homogenization time was 12 mins.

[0045] Example 2: A camellia oil composition for soothing dry, itchy and red skin, comprising, by weight, 10 parts of camellia oil; 2 parts of natural vitamin E; 40 parts of glycerol; 2 parts of a nonionic emulsifier; and 6 parts of water. The camellia oil contains 1620 mg / kg of triterpene alcohol and 112 mg / kg of squalene. The nonionic emulsifier comprises polyglyceryl-6 stearate and glyceryl stearate in a 1:1 mass ratio.

[0046] The preparation method of the camellia oil composition for relieving dry, itchy and red skin comprises the following steps: Preparation of camellia oil: A) Impurity Removal: Filter the cold-pressed camellia oil through a 400-mesh filter to remove impurities including colloids and debris, reducing the impurity content to less than 0.2 wt%; B) Alkali Refining: Take 100 kg by weight of filtered crude camellia oil, raise the temperature to 70°C, add 10% by mass sodium hydroxide aqueous solution, stir until soap particles separate from the oil layer, let it stand for 24 hours, and remove impurities and water in the lower layer by sedimentation separation to obtain alkali-refined crude camellia oil; C) Water washing: heating the alkali-refined camellia oil to 80°C, washing it once with a 5% sodium chloride aqueous solution and twice with pure water to obtain washed camellia oil; D) Dehydration: heating the washed camellia oil to 90°C and maintaining the temperature until the oil is completely dehydrated to obtain dehydrated camellia oil; E) Decolorization: When the temperature of the dehydrated crude camellia oil is controlled to 75°C and the vacuum degree is controlled at -0.10 to -0.098 MPa, a decolorizer (10% by weight of the crude camellia oil) is added. The decolorizer is a mixture of activated carbon and activated clay. The mass ratio of activated carbon to activated clay is 1:15. After decolorization for 40 minutes, the decolorized crude camellia oil is obtained. The color of the decolorized crude camellia oil is light yellow. F) Deodorization: The crude camellia oil is heated to 210°C and deodorized for 3 hours under a vacuum degree of -0.10 to -0.098 MPa to obtain deodorized camellia oil, which is then filtered to obtain camellia oil.

[0047] (2) Dissolve glycerin, water and nonionic emulsifier completely at 75°C and mix them evenly to form the aqueous phase; (3) Mix camellia oil and natural vitamin E at 57°C and stir to obtain the oil phase; (4) The oil phase and the water phase were mixed uniformly at 70° C. and homogenized under high pressure to obtain the camellia oil composition for relieving dry, itchy and red skin; the homogenization speed was 2700 rpm, the pressure was 120 MPa, and the homogenization time was 12 mins.

[0048] Example 3: A camellia oil composition for soothing dry, itchy and red skin, comprising, by weight, 20 parts of camellia oil; 4 parts of natural vitamin E; 60 parts of glycerin; 4 parts of a nonionic emulsifier; and 8 parts of water. The camellia oil contains 1580 mg / kg of triterpene alcohol and 113 mg / kg of squalene. The nonionic emulsifier comprises polyglyceryl-6 stearate and glyceryl stearate in a mass ratio of 1.5:1.

[0049] The preparation method of the camellia oil composition for relieving dry, itchy and red skin comprises the following steps: Preparation of camellia oil: A) Impurity Removal: Filter the cold-pressed camellia oil through a 400-mesh filter to remove impurities including colloids and debris, reducing the impurity content to less than 0.2 wt%; B) Alkali Refining: Take 100 kg by weight of filtered crude camellia oil, raise the temperature to 70°C, add 10% by mass sodium hydroxide aqueous solution, stir until soap particles separate from the oil layer, let it stand for 24 hours, and remove impurities and water in the lower layer by sedimentation separation to obtain alkali-refined crude camellia oil; C) Water washing: heating the alkali-refined camellia oil to 80°C, washing it once with a 5% sodium chloride aqueous solution and twice with pure water to obtain washed camellia oil; D) Dehydration: heating the washed camellia oil to 90°C and maintaining the temperature until the oil is completely dehydrated to obtain dehydrated camellia oil; E) Decolorization: When the temperature of the dehydrated crude camellia oil is controlled to 75°C and the vacuum degree is controlled at -0.10 to -0.098 MPa, a decolorizer (10% by weight of the crude camellia oil) is added. The decolorizer is a mixture of activated carbon and activated clay. The mass ratio of activated carbon to activated clay is 1:15. After decolorization for 40 minutes, the decolorized crude camellia oil is obtained. The color of the decolorized crude camellia oil is light yellow. F) Deodorization: The crude camellia oil is heated to 220°C and deodorized for 3 hours under a vacuum degree of -0.10 to -0.098 MPa to obtain deodorized camellia oil, which is then filtered to obtain camellia oil.

[0050] (2) Dissolve glycerin, water and nonionic emulsifier completely at 75°C and mix them evenly to form the aqueous phase; (3) Mix camellia oil and natural vitamin E at 57°C and stir to obtain the oil phase; (4) The oil phase and the water phase were mixed uniformly at 70° C. and homogenized under high pressure to obtain the camellia oil composition for relieving dry, itchy and red skin; the homogenization speed was 2700 rpm, the pressure was 120 MPa, and the homogenization time was 12 mins.

[0051] Comparative Example 1 (the content of triterpene alcohol is too low): The difference between Comparative Example 1 and Example 1 is that the content of triterpene alcohol in camellia oil is 780 mg / kg; the content of squalene is 110 mg / kg; The preparation method of camellia oil is: A) Impurity Removal: Filter the cold-pressed camellia oil through a 400-mesh filter to remove impurities including colloids and debris, reducing the impurity content to less than 0.2 wt%; B) Alkali Refining: Take 100 kg by weight of filtered crude camellia oil, raise the temperature to 70°C, add 10% by mass sodium hydroxide aqueous solution, stir until soap particles separate from the oil layer, let it stand for 24 hours, and remove impurities and water in the lower layer by sedimentation separation to obtain alkali-refined crude camellia oil; C) Water washing: heating the alkali-refined camellia oil to 80°C, washing it once with a 5% sodium chloride aqueous solution and twice with pure water to obtain washed camellia oil; D) Dehydration: heating the washed camellia oil to 90°C and maintaining the temperature until the oil is completely dehydrated to obtain dehydrated camellia oil; E) Decolorization: When the temperature of the dehydrated crude camellia oil is controlled to 80°C and the vacuum degree is controlled at -0.10 to -0.098 MPa, a decolorizer (10% by weight of the crude camellia oil) is added. The decolorizer is a mixture of activated carbon and activated clay. The mass ratio of activated carbon to activated clay is 1:15. After decolorization for 40 minutes, the decolorized crude camellia oil is obtained. The color of the decolorized crude camellia oil is light yellow. F) Deodorization: The crude camellia oil is heated to 240°C and deodorized for 3 hours under a vacuum degree of -0.10 to -0.098 MPa to obtain deodorized camellia oil, which is then filtered to obtain camellia oil.

[0052] The rest are the same as in Example 1.

[0053] Comparative Example 2 (squalene content is too low): The difference between Comparative Example 2 and Example 1 is that the content of triterpene alcohol in camellia oil is 1560 mg / kg; the content of squalene is 40 mg / kg; The preparation method of camellia oil is: A) Impurity Removal: Filter the cold-pressed camellia oil through a 400-mesh filter to remove impurities including colloids and debris, reducing the impurity content to less than 0.2 wt%; B) Alkali Refining: Take 100 kg by weight of filtered crude camellia oil, raise the temperature to 70°C, add 10% by mass sodium hydroxide aqueous solution, stir until soap particles separate from the oil layer, let it stand for 24 hours, and remove impurities and water in the lower layer by sedimentation separation to obtain alkali-refined crude camellia oil; C) Water washing: heating the alkali-refined camellia oil to 80°C, washing it once with a 5% sodium chloride aqueous solution and twice with pure water to obtain washed camellia oil; D) Dehydration: heating the washed camellia oil to 90°C and maintaining the temperature until the oil is completely dehydrated to obtain dehydrated camellia oil; E) Decolorization: When the temperature of the dehydrated crude camellia oil is controlled to 95°C and the vacuum degree is controlled at -0.10 to -0.098 MPa, a decolorizer (10% by weight of the crude camellia oil) is added. The decolorizer is a mixture of activated carbon and activated clay. The mass ratio of activated carbon to activated clay is 1:15. After decolorization for 40 minutes, the decolorized crude camellia oil is obtained. The color of the decolorized crude camellia oil is light yellow. F) Deodorization: The crude camellia oil is heated to 220°C and deodorized for 3 hours under a vacuum degree of -0.10 to -0.098 MPa to obtain deodorized camellia oil, which is then filtered to obtain camellia oil.

[0054] The rest are the same as in Example 1.

[0055] Comparative Example 3 (without adding vitamin E): A camellia oil composition for soothing dry, itchy and red skin, comprising, by weight, 20 parts of camellia oil, 60 parts of glycerin, 4 parts of a nonionic emulsifier, and 8 parts of water. The camellia oil comprises 1550 mg / kg of triterpene alcohol and 108 mg / kg of squalene. The nonionic emulsifier comprises polyglycerol-6 stearate and glyceryl stearate in a mass ratio of 1:1. The preparation method of the camellia oil is the same as that in Example 1.

[0056] Comparative Example 4 (Replacing nonionic emulsifier type 1): The difference between Comparative Example 4 and Example 1 is that the nonionic emulsifier includes PEG-100 stearate and glyceryl stearate in a mass ratio of 1:1. The rest is the same as in Example 1.

[0057] Comparative Example 5 (Replacing nonionic emulsifier type 2): The difference between Comparative Example 5 and Example 1 is that the nonionic emulsifier includes polyglycerol-6 stearate and hydrogenated lecithin in a mass ratio of 1:1; the rest are the same as in Example 1.

[0058] Comparative Example 6 (nonionic emulsifier using only polyglycerol-6 stearate): The difference between Comparative Example 6 and Example 1 is that the nonionic emulsifier is polyglyceryl-6 stearate; the rest is the same as in Example 1.

[0059] Comparative Example 7 (nonionic emulsifier only uses glyceryl stearate): The difference between Comparative Example 7 and Example 1 is that the nonionic emulsifier is glyceryl stearate; the rest is the same as in Example 1.

[0060] Comparative Example 8 (the ratio of polyglyceryl-6 stearate and glyceryl stearate is not within the scope of the present invention): The difference between Comparative Example 8 and Example 1 is that the mass ratio of polyglycerol-6 stearate and glyceryl stearate in the nonionic emulsifier is 0.8:1; the rest is the same as in Example 1.

[0061] The compositions in Examples 1 to 3 and Comparative Examples 1 to 3 were tested for their effectiveness in relieving dry, itchy, and red skin. Interleukin IL-1a induces heat and mediates inflammation, while aIL-8 exacerbates the inflammatory response, dilates capillaries, and causes skin irritation and redness. Prostaglandin PGE2 dilates blood vessels and is closely related to redness, swelling, heat, and pain in the skin. Thymic stromal lymphopoietin (TSLP) directly stimulates the skin's sensory nerve fibers to produce an itchy sensation, which is closely related to skin itching. Filaggrin (FLG) forms a solid physical barrier in the outermost layer of the epidermis, preventing the loss of epidermal moisture and preventing dry and flaky skin.

[0062] Soothing effect test method: Human keratinocytes were used to create an in vitro injury model using LPS. The soothing effect on dry, itchy and red skin was evaluated by measuring the expression of inflammatory factors (IL-1a, IL-8, PGE2 and TSLP) and the moisturizing protein FLG. Figures 1 to 5 As shown in .

[0063] from Figures 1 to 5 It can be seen that the camellia oil composition prepared by the formula and method of the present invention in Examples 1 to 3 significantly reduces the inflammatory factors IL-1a, IL-8, PGE2 and TSLP, and significantly increases the expression level of filaggrin FLG, and has a good effect in soothing dry, itchy and red skin.

[0064] However, the content of triterpene alcohol or squalene in the camellia oil of Comparative Examples 1 and 2 is not within the scope of the present invention. The camellia oil composition has weaker inhibition on the expression of inflammatory factors IL-1a, IL-8, PGE2 and TSLP than the embodiment. At the same time, it is also significantly weaker than the embodiment in terms of the expression of filaggrin FLG. The soothing effect of Comparative Examples 1 and 2 is significantly reduced compared with that in the embodiment, indicating that triterpene alcohol and squalene have a synergistic effect on soothing dry, itchy and red skin.

[0065] The composition of Comparative Example 3, which does not contain natural vitamin E, showed weaker expression of the inflammatory factors IL-1a, IL-8, PGE2, and TSLP than that of Example 3, and the expression of FLG was also significantly lower than that of Example 3. The soothing effect of Comparative Example 3 was somewhat lower than that of Example 3, indicating that natural vitamin E can synergistically resist skin damage caused by external stimuli with camellia oil.

[0066] The stability of the compositions in Examples 1 to 3 and Comparative Example 3 was evaluated.

[0067] Stability Evaluation Method: The camellia oil compositions of Examples 1-3 and Comparative Example 3 were packaged in transparent PET plastic bottles and stored in thermostats at -10°C, 25°C, and 45°C for three months. After removal from the thermostats and returning to room temperature, the appearance and odor of the compositions were observed. The triterpene alcohol and squalene contents of the camellia oil compositions were measured at the initial and three-month intervals, and the loss rates of triterpene alcohol and squalene were calculated. Loss rate (%) = (initial content - content at three months) / (initial content) × 100%. The results are shown in Table 1.

[0068] Table 1: Stability test results of Examples 1 to 3 and Comparative Example 3

[0069] As shown in Table 1, the camellia oil compositions of Examples 1-3 maintained normal appearance and odor after three months of storage at high and low temperatures. Triterpene alcohol and squalene content showed no degradation, demonstrating the long-term stability of the camellia oil compositions of the present invention and their ability to stably retain the active ingredients, maintaining their efficacy in soothing dry, itchy, and red skin. The composition of Comparative Example 3, devoid of natural vitamin E, exhibited improved stability compared to the examples. However, at room and high temperatures, the composition exhibited a change in odor, producing an oily, pungent odor. This demonstrates that natural vitamin E stabilizes the triterpene alcohol and squalene active ingredients in camellia oil.

[0070] The camellia oil compositions prepared in Examples 1-3 and Comparative Examples 4-8 were centrifuged at 4000 rpm for 30 minutes and observed. The camellia oil compositions were then packaged into transparent PET bottles and stored in thermostats at -10°C, 25°C, and 45°C. The appearance of the camellia oil compositions was observed after returning to room temperature at the initial temperature, one month, two months, and three months. The results are shown in Table 2.

[0071] Table 2: Centrifugation and long-term stability test results of Examples 1 to 3 and Comparative Examples 4 to 8

[0072] Comparative Example 4 uses the nonionic emulsifier PEG-100 stearate commonly used in the art to replace the polyglycerol-6 stearate in the present invention. The surface of the prepared camellia oil composition is slightly oiled after centrifugation. The composition becomes rough at low temperatures and oil is produced on the high-temperature surface, indicating that the emulsification performance of the camellia oil composition of Comparative Example 4 decreases. Comparative Example 5 uses the nonionic emulsifier hydrogenated lecithin commonly used in the art to replace the glycerol stearate in the present invention. The prepared camellia oil composition emulsion is rough, centrifuged and oil is produced. Low, medium and high temperatures all cause demulsification and stratification, indicating that the emulsification performance of Comparative Example 5 is seriously reduced. In Comparative Examples 6 and 7, only polyglycerol-6 stearate or glycerol stearate is used as an emulsifier, and the two are not compounded, and the emulsification performance of the composition is seriously reduced. The ratio of glycerol-6 stearate or glycerol stearate in Comparative Example 8 is so that the ratio of the two is not within the scope of the present invention. The initial state of the composition is normal, but the long-term stability is abnormal at low and high temperatures, indicating that the emulsification performance of the comparative example 8 composition is all reduced. This indicates that when the content of triterpenoid alcohol or squalene in camellia oil is high, specific emulsifiers are required to achieve a better emulsification effect.

[0073] Application Example 1: The composition prepared in Example 1 was added to shampoo at a ratio of 1%, stirred evenly, and then stored at -10°C, 25°C, and 45°C for 3 months to observe the stability of the shampoo containing the camellia oil composition. The results are as follows: Figure 6 As shown in .

[0074] Application Example 2: The composition prepared in Example 3 was added to a baby cream product at a ratio of 5%, stirred evenly, and then stored at -10°C, 25°C, and 45°C for 3 months to observe the stability of the baby cream shampoo containing the camellia oil composition. The results are as follows: Figure 7 As shown in .

[0075] from Figure 6 and Figure 7 As can be seen, the shampoo prepared from the camellia oil composition in Example 1 remained unchanged after three months of storage at low, medium, and high temperatures, remaining consistent with its initial state. The baby cream prepared from the camellia oil composition in Example 3 remained unchanged after three months of storage at low, medium, and high temperatures, remaining consistent with its initial state. This demonstrates that the camellia oil composition prepared using the formulation and method of the present invention can be directly applied to lotions and creams, and the applied products exhibit excellent stability.

Claims

1. A camellia oil composition for relieving dry, itchy and red skin, characterized in that: In parts by weight, the components include: Camellia oil: 0.5-30 parts; Natural vitamin E: 0.2~5 parts; Glycerin: 20~70 parts; Nonionic emulsifier: 0.1~5 parts; Water: 1-10 parts; The camellia oil has a triterpene alcohol content of ≥1500 mg / kg and a squalene content of ≥100 mg / kg. The nonionic emulsifier includes polyglyceryl-6 stearate and glyceryl stearate.

2. The camellia oil composition for relieving dry, itchy and red skin according to claim 1, wherein: In the nonionic emulsifier, the mass ratio of polyglycerol-6 stearate to glyceryl stearate is 1-1.5:

1.

3. The camellia oil composition for relieving dry, itchy and red skin according to claim 1, wherein: In parts by weight, the components include: Camellia oil: 5-20 parts; Natural vitamin E: 0.5~4 parts; Glycerin: 30~60 parts; Nonionic emulsifier: 0.5~4 parts; Water: 2~8 parts 4. A method for preparing a camellia oil composition for relieving dry, itchy and red skin according to any one of claims 1 to 3, characterized in that: The steps include: (1) Preparation of camellia oil with a triterpene alcohol content of ≥1500 mg / kg and a squalene content of ≥100 mg / kg; (2) Heat and dissolve glycerin, water and non-ionic emulsifier completely and mix them evenly to form the water phase; (3) Heat and stir camellia oil and natural vitamin E to mix evenly as the oil phase; (4) The oil phase and the water phase are mixed evenly and homogenized under high pressure to obtain the camellia oil composition for relieving dry, itchy and red skin.

5. The method for preparing the camellia oil composition for relieving dry, itchy and red skin according to claim 4, wherein: The preparation method of camellia oil in step (1) is as follows: filtering and alkali-refining the crude camellia seed oil obtained by pressing camellia seeds, washing the oil with water, dehydrating the oil, and then decolorizing and deodorizing the oil under vacuum, and finally filtering the oil to obtain the camellia oil; the decolorization temperature is 70-80°C, and the deodorization temperature is 200-230°C.

6. The method for preparing the camellia oil composition for relieving dry, itchy and red skin according to claim 4, wherein: The heating and dissolving temperature in step (2) is 60-80°C.

7. The method for preparing the camellia oil composition for relieving dry, itchy and red skin according to claim 4, wherein: The heating and stirring temperature in step (3) is 55~75℃.

8. The method for preparing the camellia oil composition for relieving dry, itchy and red skin according to claim 4, wherein: In step (4), the temperature is maintained at 65-80°C when the oil phase and the water phase are mixed.

9. The method for preparing the camellia oil composition for relieving dry, itchy and red skin according to claim 4 or 8, wherein: The speed during homogenization in step (4) is 2600-3000 rpm, the pressure is 110-140 MPa, and the homogenization time is 10-20 mins.

10. The method for preparing the camellia oil composition for relieving dry, itchy and red skin according to claim 4 or 8, wherein: After homogenization in step (4), the mixture is stirred and cooled to below 45° C. to obtain the camellia oil composition for relieving dry, itchy and red skin.

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