Scraping massage cream capable of dredging meridians and collaterals and use method of scraping massage cream

Abstract

The invention discloses a scraping massage cream for dredging meridians and collaterals and a use method thereof, and particularly relates to the technical field of scraping massage cream, the scraping massage cream for dredging meridians and collaterals comprises the following raw materials by weight: 5-15 parts of crocus sativus oil, 3-10 parts of ginger root oil, 8-20 parts of holly essential oil, 10-30 parts of a polygonum cuspidatum extract, 40-60 parts of matrix oil, 3-8 parts of an emulsifier, and 0.5-2 parts of a preservative. According to the scraping massage cream capable of dredging the channels and collaterals and the use method of the scraping massage cream, the transdermal enhancer composed of azone and glyceryl oleate is added, and a special preparation process of the polygonum cuspidatum extract is adopted, so that the transdermal absorption rate of the massage cream is remarkably increased, and the transdermal permeability coefficient is increased to 2.78 * 10 <-3 > cm / h and is greatly increased compared with 1.12 * 10 <-3 > of a control group; active ingredients can be effectively transmitted to muscles and meridians and collaterals, natural vegetable oil is adopted as base oil, and the kinematic viscosity of the base oil is controlled within a proper range.

Description

Technical Field

[0001] The invention relates to the technical field of scraping massage creams, and in particular to a meridian-dredging scraping massage cream and a use method thereof. Background Art

[0002] The main problems of traditional scraping massage creams are unnatural ingredients, limited efficacy, and strong irritation. Most massage creams on the market currently use artificial synthetic chemicals. Although they can relieve some muscle soreness and joint discomfort to a certain extent, long-term use may cause irritation to the skin. The traditional manual scraping massage process has disadvantages such as difficulty in controlling the strength and low efficiency. At the same time, the existing technology lacks systematic optimization of the transdermal absorption effect and skin irritation of massage creams, and there are deficiencies in the innovation of the coordinated use of equipment and massage creams. Summary of the Invention

[0003] The main purpose of the present invention is to provide a meridian-opening scraping massage cream and a method of using the same, which can effectively solve the problems in the background technology.

[0004] To achieve the above object, the technical solution adopted by the present invention is:

[0005] A meridian-dredging scraping massage cream and a use method thereof are prepared from the following raw materials in parts by weight: 5-15 parts of saffron oil, 3-10 parts of ginger root oil, 8-20 parts of wintergreen essential oil, 10-30 parts of knotweed extract, 40-60 parts of base oil, 3-8 parts of emulsifier, and 0.5-2 parts of preservative.

[0006] Preferably, the knotweed extract is prepared by supercritical CO2 extraction, the extraction conditions are pressure 25-35 MPa, temperature 45-55° C., extraction time 2-4 hours, and the entrainer is 70% by volume ethanol.

[0007] Preferably, the base oil is selected from sweet almond oil, jojoba oil and grape seed oil, and the kinematic viscosity (40°C) is 15-25 mm 2 / s.

[0008] Preferably, the emulsifier is olive wax, beeswax and candelilla wax, and the HLB value is controlled between 6 and 8.

[0009] Preferably, the scraping massage cream contains 0.1-0.5 parts of a transdermal enhancer, and the transdermal enhancer is a mixture of azone and glyceryl oleate in a mass ratio of 1:2-4.

[0010] Preferably, the preservative is a composite preservative system consisting of vitamin E and rosemary extract in a mass ratio of 3:1.

[0011] The present invention also discloses a method for applying a meridian-opening scraping massage cream. The device used in the method includes a paste storage box. A high-frequency electric massage ball head is threadedly connected to the upper portion of the inner surface of the paste storage box. A plurality of medical silicone scraping blades are fixedly connected in a circular array on the outer side of the upper end of the high-frequency electric massage ball head. Four Tai Chi balls distributed in a matrix are rotatably connected to the middle portion of the upper end of the high-frequency electric massage ball head. Four medical silicone scraping blades distributed in a matrix are fixedly connected to the middle portion of the upper end of the paste storage box. The four medical silicone scraping blades are located outside the four Tai Chi balls. The method includes the following steps:

[0012] S1. First, rotate the high-frequency electric massage ball head from the upper inner surface of the paste storage box to open it, then pour the prepared scraping massage cream into the paste storage box, and then rotate the high-frequency electric massage ball head again to tighten it on the upper inner surface of the paste storage box;

[0013] S2. Next, according to the location of the scraping massage, the upper end of the high-frequency electric massage ball head is attached to the corresponding location, and then the paste storage box is squeezed to make the prepared scraping massage cream seep out from the four Tai Chi balls;

[0014] S3. Then, hold the paste storage box and start to rotate it so that the high-frequency electric massage ball head connected to the paste storage box rotates close to the scraping massage position, so that the medical silicone scraping pad 1, the medical silicone scraping pad 2 and the Tai Chi roller can fully perform scraping massage on the corresponding skin positions, and in the process of rotating, the scraping massage cream can be evenly spread on the skin surface so that the skin can fully absorb it.

[0015] Compared with the prior art, the present invention has the following beneficial effects:

[0016] 1. The present invention significantly improves the transdermal absorption rate of the massage cream by adding a transdermal enhancer composed of azone and olein, and a special preparation process for the knotweed extract. The transdermal permeability coefficient is increased to 2.78×10-3cm / h, which is a significant increase compared to 1.12×10-3 in the control group, and can more effectively deliver the active ingredients to the muscles and meridians.

[0017] 2. The present invention adopts natural plant oil (sweet almond oil, jojoba oil, etc.) as matrix oil, controls the kinematic viscosity of the matrix oil within an appropriate range, and adds vitamin E and rosemary extract to form a composite preservative system, thereby reducing skin irritation. The skin irritation in comparative example 1 is only 0.12 points, indicating that the massage cream is relatively mild to the skin and suitable for long-term use.

[0018] 3. The massage equipment of the present invention includes a paste storage box, a high-frequency electric massage ball head, a medical silicone scraping blade 1, a medical silicone scraping blade 2 and a Tai Chi ball and other components. By pouring the prepared massage cream into the storage box, squeezing the paste to make the massage cream seep out from the Tai Chi ball, and then holding the storage box in circles, the scraping blade and the ball can fully perform scraping massage on the skin. The operation is simple and the massage strength and range can be accurately controlled, thereby improving the massage effect. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 This is a schematic diagram of the overall structure of the scraping massage cream application device of the present invention;

[0020] In the picture: 1. Paste storage box; 2. High-frequency electric massage ball head; 3. Medical silicone scraping pad 1; 4. Medical silicone scraping pad 2; 5. Tai Chi roller. DETAILED DESCRIPTION

[0021] In order to make the technical means, creative features, objectives and effects achieved by the present invention easier to understand, the present invention is further described below in conjunction with specific implementation methods.

[0022] The present application uses the prepared meridian-opening scraping massage cream according to the following usage method:

[0023] The device used in this method includes a paste storage box 1, a high-frequency electric massage ball head 2 is threadedly connected to the upper inner surface of the paste storage box 1, a plurality of medical silicone scraping blades 3 are fixedly connected in a ring array on the outer side of the upper end of the high-frequency electric massage ball head 2, four Tai Chi balls 5 distributed in a matrix are rotatably connected to the middle of the upper end of the high-frequency electric massage ball head 2, four medical silicone scraping blades 2 4 distributed in a matrix are fixedly connected to the middle of the upper end of the paste storage box 1, and the four medical silicone scraping blades 2 4 are located outside the four Tai Chi balls 5. The method includes the following steps:

[0024] S1. First, rotate the high-frequency electric massage ball head 2 from the upper inner surface of the paste storage box 1 to open it, then pour the prepared scraping massage cream into the paste storage box 1, and then rotate the high-frequency electric massage ball head 2 again to tighten it on the upper inner surface of the paste storage box 1;

[0025] S2. Next, according to the location of scraping massage required, the upper end of the high-frequency electric massage ball head 2 is attached to the corresponding location required, and then the paste storage box 1 is squeezed to make the prepared scraping massage cream seep out from the four Tai Chi balls 5;

[0026] S3. Then, hold the paste storage box 1 and start to rotate, so that the high-frequency electric massage ball head 2 connected to the paste storage box 1 rotates close to the scraping massage position, so that the medical silicone scraping piece 1 3, the medical silicone scraping piece 2 4 and the Tai Chi roller 5 can fully perform scraping massage at the corresponding skin positions, and in the process of rotating, the scraping massage cream can be fully spread on the skin surface so that the skin can fully absorb it.

[0027] Example 1. The formula of the meridian-opening scraping massage cream prepared in this example includes the following raw materials by weight: saffron oil: 10 parts, ginger root oil: 6 parts, wintergreen essential oil: 15 parts, knotweed extract: 20 parts, base oil: sweet almond oil 50 parts, emulsifier: olive wax 6 parts, preservative: vitamin E 1.2 parts.

[0028] Example 2, a formula for a meridian-opening scraping massage cream, the raw materials of which include, by weight:

[0029] Saffron oil: 8 parts, ginger root oil: 8 parts, wintergreen essential oil: 18 parts, knotweed extract: 25 parts, matrix oil: jojoba oil 35 parts + grape seed oil 10 parts, emulsifier: lecithin 7 parts, transdermal enhancer: azone 0.3 parts + oleic acid glyceride 0.6 parts.

[0030] Example 3, a formula for a meridian-opening scraping massage cream, the raw materials of which include, by weight:

[0031] Saffron oil: 12 parts, ginger root oil: 5 parts, wintergreen essential oil: 12 parts, knotweed extract: 22 parts, base oil: camellia seed oil 45 parts, emulsifier: beeswax 5 parts + candelilla wax 2 parts, sustained-release regulator: 0.5 parts.

[0032] Example 4, a formula for a meridian-opening scraping massage cream, the raw materials of which include, by weight:

[0033] Saffron oil: 15 parts, ginger root oil: 10 parts, wintergreen essential oil: 20 parts, knotweed extract: 30 parts, matrix oil: shea butter 30 parts + evening primrose oil 15 parts, functional additives: ligustrazine 0.3 parts, menthol 1.2 parts, nano silicon dioxide 2 parts.

[0034] Comparative Example 1

[0035] A material formula of a meridian-dredging scraping massage cream, the raw materials of which include, by weight:

[0036] Saffron oil: 9 parts, ginger root oil: 6 parts, wintergreen essential oil: 14 parts, knotweed extract: 20 parts, base oil: sweet almond oil 50 parts, emulsifier: olive wax 6 parts, preservative: vitamin E 1.2 parts.

[0037] The knotweed extract is prepared by supercritical CO2 extraction method, the extraction conditions are pressure 25-35MPa, temperature 45-55°C, extraction time 2-4 hours, and the entrainer is ethanol with a volume fraction of 70%.

[0038] The matrix oil is selected from sweet almond oil, jojoba oil and grape seed oil, and the kinematic viscosity (40°C) is 15-25mm 2 / s.

[0039] The emulsifiers are olive wax, beeswax and candelilla wax, and the HLB value is controlled between 6 and 8.

[0040] The scraping massage cream contains 0.1-0.5 parts of a transdermal enhancer, which is a mixture of azone and olein in a mass ratio of 1:2-4.

[0041] The preservative is a composite preservative system composed of vitamin E and rosemary extract in a mass ratio of 3:1.

[0042] 1. Matrix pretreatment: Place sweet almond oil in a constant temperature oil bath at 60±2°C (model DF-101S), add olive wax and emulsify with a magnetic stirrer (800 rpm) for 15 minutes;

[0043] 2. Essential oil mixing: Add saffron oil, ginger root oil, and wintergreen essential oil in sequence, transfer to a high-speed shear emulsifier (T25, 12000 rpm) and homogenize for 3 minutes;

[0044] 3. Addition of active ingredients: Process the Polygonum cuspidatum extract with a nano-crusher (NM200) until D90 ≤ 200 nm, then add it and stir at low speed (400 rpm) for 20 minutes;

[0045] 4. Post-treatment: Add vitamin E when the temperature drops to 40°C, filter through a 0.22 μm microporous membrane, and then degas in vacuo (-0.08 MPa, 30 min).

[0046] Test data:

[0047] 1. Using Franz diffusion cell method, the cumulative permeation volume was measured over 24 hours, and the transdermal absorption rate was 68.3%;

[0048] 2. Using the rabbit skin occlusion test method, the skin irritation was measured: 0.12 points;

[0049] 3. Clinical effect: A double-blind test was conducted on 50 patients with frozen shoulder. The VAS pain score decreased by 62.7% after 7 days.

[0050] Comparative Example 2

[0051] A material formula of a meridian-dredging scraping massage cream, the raw materials of which include, by weight:

[0052] Saffron oil: 8 parts, ginger root oil: 9 parts, wintergreen essential oil: 17 parts, knotweed extract: 25 parts, matrix oil: jojoba oil 35 parts + grape seed oil 10 parts, emulsifier: lecithin 7 parts, transdermal enhancer: azone 0.3 parts + oleic acid glyceride 0.6 parts.

[0053] The knotweed extract is prepared by supercritical CO2 extraction method, the extraction conditions are pressure 25-35MPa, temperature 45-55°C, extraction time 2-4 hours, and the entrainer is ethanol with a volume fraction of 70%.

[0054] The matrix oil is selected from sweet almond oil, jojoba oil and grape seed oil, and the kinematic viscosity (40°C) is 15-25mm 2 / s.

[0055] The emulsifiers are olive wax, beeswax and candelilla wax, and the HLB value is controlled between 6 and 8.

[0056] The scraping massage cream contains 0.1-0.5 parts of a transdermal enhancer, which is a mixture of azone and olein in a mass ratio of 1:2-4.

[0057] The preservative is a composite preservative system composed of vitamin E and rosemary extract in a mass ratio of 3:1.

[0058] 1. Use high-pressure microfluidization technology (150MPa) to treat the mixed oil phase, with a particle size of D50 = 85nm;

[0059] 2. Polygonum cuspidatum extract was encapsulated by β-cyclodextrin (encapsulation efficiency 92.3%);

[0060] 3. Add phase change temperature regulator (2 parts of hexadecanol).

[0061] Effect verification:

[0062] 1. Transdermal permeability coefficient increased to 2.78×10 -3 cm / h (control group 1.12×10 -3 );

[0063] 2. After scraping, the blood flow velocity of skin microcirculation increased by 158% (laser Doppler detection);

[0064] 3. After using it on 30 patients with lumbar disc herniation, the ODI dysfunction index improved by 51.4%.

[0065] Comparative Example 3

[0066] A material formula of a meridian-dredging scraping massage cream, the raw materials of which include, by weight:

[0067] Saffron oil: 14 parts, ginger root oil: 10 parts, wintergreen essential oil: 20 parts, knotweed extract: 29 parts, matrix oil: shea butter 30 parts + evening primrose oil 15 parts, functional additives: ligustrazine 0.3 parts, menthol 1.2 parts, nano silicon dioxide 2 parts.

[0068] The knotweed extract is prepared by supercritical CO2 extraction method, the extraction conditions are pressure 25-35MPa, temperature 45-55°C, extraction time 2-4 hours, and the entrainer is ethanol with a volume fraction of 70%.

[0069] The matrix oil is selected from sweet almond oil, jojoba oil and grape seed oil, and the kinematic viscosity (40°C) is 15-25mm 2 / s.

[0070] The emulsifiers are olive wax, beeswax and candelilla wax, and the HLB value is controlled between 6 and 8.

[0071] The scraping massage cream contains 0.1-0.5 parts of a transdermal enhancer, which is a mixture of azone and olein in a mass ratio of 1:2-4.

[0072] The preservative is a composite preservative system composed of vitamin E and rosemary extract in a mass ratio of 3:1.

[0073] 1. Using Franz diffusion cell method, the cumulative permeation volume was measured over 24 hours, and the transdermal absorption rate was 32.1%;

[0074] 2. Using the rabbit skin occlusion test method, the skin irritation was measured: 0.15 points;

[0075] 3. Clinical effect: A double-blind test was conducted on 50 patients with periarthritis of the shoulder. The VAS pain score decreased by 60% after 7 days.

[0076] The test results of the scraping massage creams of Comparative Examples 1-3 are shown in Table 1:

[0077] Table 1 Comparison of key technical indicators of scraping massage cream embodiment and comparative example

[0078]

[0079] Comparative Example Description:

[0080] Comparative Example 1: The Knotweed Extract was omitted and replaced with an equal amount of base oil;

[0081] Effect attenuation: The improvement rate of meridian blockage decreased by 29.7%, proving that the knotweed extract is the core active ingredient.

[0082] Comparative Example 2: Traditional hot reflux extraction (ethanol concentration 60%, extraction 3 times) was used instead of supercritical CO2 extraction;

[0083] The resveratrol content was reduced by 58.3% (2.3 mg / g vs 5.5 mg / g), resulting in a 36% decrease in transdermal absorption rate.

[0084] Comparative Example 3: Eliminate the transdermal enhancer and reduce the amount of emulsifier (3 parts → 1.5 parts);

[0085] The stability of the paste decreased (oil-water separation occurred in the centrifugation test) and the transdermal time delay was prolonged by 2.3 times.

[0086] The best comprehensive performance: Comparative Example 2 performed outstandingly in terms of rapid effect (onset time 6.2 minutes) and safety (irritation index 0.08).

[0087] The basic principles, main features, and advantages of the present invention are shown and described above. Those skilled in the art should understand that the present invention is not limited to the above embodiments. The above embodiments and descriptions are merely illustrative of the principles of the present invention. Various changes and modifications may be made to the present invention without departing from the spirit and scope of the present invention. Such changes and modifications are intended to fall within the scope of the present invention. The scope of protection claimed in the present invention is defined by the appended claims and their equivalents.

Claims

1. A meridian-dredging scraping massage cream, characterized in that: The invention is prepared from the following raw materials in parts by weight: 5-15 parts of saffron oil, 3-10 parts of ginger root oil, 8-20 parts of wintergreen essential oil, 10-30 parts of knotweed extract, 40-60 parts of base oil, 3-8 parts of emulsifier and 0.5-2 parts of preservative.

2. The meridian-opening scraping massage cream according to claim 1, characterized in that: The knotweed extract is prepared by supercritical CO2 extraction method, the extraction conditions are pressure 25-35MPa, temperature 45-55°C, extraction time 2-4 hours, and the entrainer is ethanol with a volume fraction of 70%.

3. The meridian-opening scraping massage cream according to claim 1, characterized in that: The matrix oil is selected from sweet almond oil, jojoba oil and grape seed oil, and the kinematic viscosity (40°C) is 15-25mm 2 / s.

4. The meridian-opening scraping massage cream according to claim 1, characterized in that: The emulsifiers are olive wax, beeswax and candelilla wax, and the HLB value is controlled between 6 and 8.

5. The meridian-opening scraping massage cream according to claim 1, characterized in that: The scraping massage cream contains 0.1-0.5 parts of a transdermal enhancer, which is a mixture of azone and olein in a mass ratio of 1:2-4.

6. The meridian-opening scraping massage cream according to claim 1, characterized in that: The preservative is a composite preservative system composed of vitamin E and rosemary extract in a mass ratio of 3:

1.

7. A method for using the meridian-opening scraping massage cream according to any one of claims 1 to 6, wherein the device used in the method comprises a paste storage box (1), a high-frequency electric massage ball head (2) is threadedly connected to the upper inner surface of the paste storage box (1), a plurality of medical silicone scraping blades (3) are fixedly connected in a circular array on the outer side of the upper end of the high-frequency electric massage ball head (2), four matrix-distributed Tai Chi balls (5) are rotatably connected to the middle of the upper end of the high-frequency electric massage ball head (2), four matrix-distributed medical silicone scraping blades (4) are fixedly connected to the middle of the upper end of the paste storage box (1), and the four medical silicone scraping blades (4) are located on the outer sides of the four Tai Chi balls (5), characterized in that: The method comprises the following steps: S1. First, rotate the high-frequency electric massage ball head (2) from the upper inner surface of the paste storage box (1) to open it, then pour the prepared scraping massage cream into the paste storage box (1), and then rotate the high-frequency electric massage ball head (2) again to tighten it on the upper inner surface of the paste storage box (1); S2. Next, according to the location of scraping massage required, the upper end of the high-frequency electric massage ball head (2) is attached to the corresponding location required, and then the paste storage box (1) is squeezed to allow the prepared scraping massage cream to seep out from the four Tai Chi balls (5); S3. Then, while holding the paste storage box (1), start to rotate in circles, so that the high-frequency electric massage ball head (2) connected to the paste storage box (1) rotates in close proximity to the scraping massage position, so that the medical silicone scraping sheet 1 (3), the medical silicone scraping sheet 2 (4) and the Tai Chi roller (5) fully perform scraping massage at the corresponding skin position, and in the process of rotating in circles, the scraping massage cream can be evenly spread on the skin surface so that the skin can fully absorb it.

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