Ultrasonic parameter adjustment method and device, electronic equipment and storage medium

Abstract

The application provides an ultrasonic parameter adjustment method and device, electronic equipment and storage medium. The method uses the temperature measured by the center temperature sensor and the multiple edge temperature sensors to calculate the area temperature of each temperature measurement area. The ultrasonic assembly is also managed in sections. The ultrasonic parameters of each ultrasonic area are adjusted or not adjusted according to the temperature measurement of each temperature measurement area. The combination of the two makes the adjustment of the ultrasonic parameters more accurate. In addition, when each temperature sensor is effective, the reference temperature difference between the center and the edge is calculated first. If the center temperature sensor fails, the center temperature can be calculated and completed according to the real-time acquisition of each edge temperature and the reference temperature difference. The center temperature is used in the subsequent area temperature calculation and area ultrasonic parameter adjustment. The center temperature sensor does not need to be replaced during the process. It can be directly calculated and adjusted, so that the efficiency of the ultrasonic parameter adjustment is improved.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of medical treatment, and in particular to an ultrasonic parameter adjustment method and device, an electronic device, and a storage medium. BACKGROUND

[0002] When ultrasonic waves act on the human body, due to the strong absorption capacity of the human body tissue to sound energy, the human body tissue absorbs the sound energy and converts it into heat during the propagation of the sound energy, thereby increasing the temperature of the human body tissue. This phenomenon is the thermal effect of ultrasonic waves. Based on the basic theory of modern tumor thermotherapy, basic experimental research, and a large number of clinical proofs, when the temperature is higher than 40℃, the cells will stop growing, and when the temperature reaches 45℃, the proteins will start to deform, and with the further increase of the temperature, the proteins will be decomposed. Due to the congenital malady of the tumor, the blood flow of the tumor is 10% of that of the surrounding tissues, and heat is easy to accumulate. Under the action of the heat source, the tumor cells are more likely to be killed than other normal tissue cells, and the normal tissue cells will restore normal functions after the temperature stops rising. Based on the above principle, the current ultrasonic probe is usually attached to the surface of the human body as a heat source to perform thermotherapy on the local malignant tumor of the maxillofacial region.

[0003] In the current thermotherapy for the maxillofacial tumor, in order to ensure the thermotherapy effect, a temperature sensor is inserted into the center of the tumor to measure the temperature, the ultrasonic parameters are adjusted according to the temperature measurement result, and the ultrasonic probe is controlled to perform thermotherapy on the tumor at the adjusted ultrasonic parameters, so that the tumor cells can be at an ideal temperature. However, this method has the following defects: first, the maxillofacial region and the tumor are not regular planes, and the heat distribution of the entire tumor is not uniform during the thermotherapy, which may cause the local temperature of the tumor to be too high, and thus there is a risk of damaging the normal tissue at the edge of the tumor. Single-point temperature measurement cannot reflect whether the temperature of the tissue at the edge of the tumor is within the normal range, resulting in inaccurate temperature measurement and thus inaccurate adjustment of the ultrasonic parameters. Second, if the temperature sensor is damaged during the thermotherapy, the temperature will be missing, the adjustment of the ultrasonic parameters will not be able to proceed normally due to the lack of data, and the temperature sensor needs to be replaced, the temperature needs to be measured again, and the adjustment of the ultrasonic parameters needs to be performed again, which reduces the efficiency of the adjustment.

[0004] Therefore, the current maxillofacial tumor thermotherapy system has the technical problems of inaccurate adjustment of the ultrasonic parameters and low efficiency of the adjustment, and needs to be improved. SUMMARY

[0005] Embodiments of the present application provide an ultrasonic parameter adjustment method and device, an electronic device, and a storage medium, to alleviate the technical problems of inaccurate adjustment of the ultrasonic parameters and low efficiency of the adjustment of the current maxillofacial tumor thermotherapy system.

[0006] To solve the above technical problems, embodiments of the present application provide the following technical solutions:

[0007] The application provides a method for adjusting ultrasonic parameters, which is suitable for a maxillofacial tumor hyperthermia system, the maxillofacial tumor hyperthermia system comprising an ultrasonic assembly and a temperature measurement assembly, the temperature measurement assembly comprising a center temperature sensor and N groups of edge temperature sensors, N being an integer not less than 2, the center temperature sensor being arranged at the center of a tumor, each group of edge temperature sensors comprising two edge temperature sensors symmetrically arranged on both sides of the center temperature sensor, the temperature measurement assembly enclosing 2N temperature measurement areas, each of the temperature measurement areas being enclosed by two adjacent edge temperature sensors and the center temperature sensor, the ultrasonic assembly comprising 2N ultrasonic areas, the 2N ultrasonic areas covering the 2N temperature measurement areas one by one, the method comprising:

[0008] real-time acquisition of a center temperature from the center temperature sensor and real-time acquisition of 2N edge temperatures from the 2N edge temperature sensors;

[0009] calculation of a reference temperature difference between the center and the edges according to the center temperature and the 2N edge temperatures;

[0010] real-time monitoring of whether the center temperature sensor is invalid;

[0011] if not, calculation of a region temperature of each temperature measurement area according to two edge temperatures and a center temperature corresponding to the temperature measurement area; if yes, calculation of a center temperature according to the 2N edge temperatures and the reference temperature difference, and calculation of a region temperature of each temperature measurement area according to two edge temperatures and a center temperature corresponding to the temperature measurement area;

[0012] real-time monitoring of whether a target region temperature of a first target temperature measurement area exceeds a preset temperature range;

[0013] if yes, determination of an ultrasonic area covering the first target temperature measurement area as a target ultrasonic area, adjustment of an initial ultrasonic parameter of the target ultrasonic area, and obtaining of a target ultrasonic parameter of the target ultrasonic area.

[0014] Meanwhile, the application further provides an ultrasonic parameter adjusting device, which is suitable for a maxillofacial tumor hyperthermia system, the maxillofacial tumor hyperthermia system comprising an ultrasonic assembly and a temperature measuring assembly, the temperature measuring assembly comprising a center temperature sensor and N groups of edge temperature sensors, N being an integer not less than 2, the center temperature sensor being arranged at the center of a tumor, each group of edge temperature sensors comprising two edge temperature sensors symmetrically arranged on both sides of the center temperature sensor, the temperature measuring assembly enclosing 2N temperature measuring areas, each of the temperature measuring areas being enclosed by two adjacent edge temperature sensors and the center temperature sensor, the ultrasonic assembly comprising 2N ultrasonic areas, the 2N ultrasonic areas covering the 2N temperature measuring areas one by one, the device comprising:

[0015] a temperature obtaining module, configured to obtain a center temperature in real time from the center temperature sensor and 2N edge temperatures in real time from the 2N edge temperature sensors;

[0016] a first calculating module, configured to calculate a reference temperature difference between the center and the edge according to the center temperature and the 2N edge temperatures;

[0017] a first monitoring module, configured to monitor whether the center temperature sensor is invalid in real time;

[0018] a second calculating module, configured to calculate a region temperature of each of the temperature measuring areas according to two edge temperatures and a center temperature corresponding to the temperature measuring area if the center temperature sensor is not invalid, and calculate a center temperature according to the 2N edge temperatures obtained in real time and the reference temperature difference, and calculate a region temperature of each of the temperature measuring areas according to two edge temperatures and a center temperature corresponding to the temperature measuring area if the center temperature sensor is invalid;

[0019] a second monitoring module, configured to monitor whether a target region temperature of a first target temperature measuring area exceeds a preset temperature range in real time;

[0020] an adjusting module, configured to determine an ultrasonic area covering the first target temperature measuring area as a target ultrasonic area, and adjust an initial ultrasonic parameter of the target ultrasonic area to obtain a target ultrasonic parameter of the target ultrasonic area if the target region temperature of the first target temperature measuring area exceeds the preset temperature range.

[0021] The application further provides an electronic device comprising a memory and a processor, wherein the memory stores an application program, and the processor is configured to run the application program in the memory to execute the steps in the ultrasonic parameter adjusting method.

[0022] The application provides a computer readable storage medium, which stores a plurality of instructions, and the instructions are suitable for being loaded by a processor to execute the steps in the ultrasonic parameter adjusting method.

[0023] Beneficial effects: The present application provides an ultrasonic parameter adjustment method and device, electronic equipment and storage medium. The maxillofacial tumor hyperthermia system includes an ultrasonic assembly and a temperature measurement assembly. The temperature measurement assembly includes a center temperature sensor and N sets of edge temperature sensors. Each temperature sensor forms 2N temperature measurement areas. The 2N ultrasonic areas formed by the ultrasonic assembly cover the 2N temperature measurement areas one by one. The method first acquires the center temperature and each edge temperature in real time, calculates the reference temperature difference between the center and the edge in real time, and monitors whether the center temperature sensor fails in real time. If it does not fail, the area temperature of each temperature measurement area is calculated according to the corresponding two edge temperatures and the center temperature. If it fails, the center temperature is calculated according to the 2N edge temperatures and the reference temperature difference obtained in real time, and the area temperature of each temperature measurement area is calculated according to the corresponding two edge temperatures and the center temperature. Finally, whether the area temperature of a certain temperature measurement area exceeds the preset temperature range is monitored in real time. If it does, the initial ultrasonic parameter of the ultrasonic area covering the temperature measurement area is adjusted to obtain the adjusted target ultrasonic parameter. The present application simultaneously uses the temperatures measured by the center temperature sensor and the multiple edge temperature sensors when measuring the temperature. The area temperature is used as the basis for real-time monitoring and adjustment when adjusting the ultrasonic parameter. Compared with using only the center temperature as the basis, the temperature measurement influence caused by uneven heat distribution can be reduced. At the same time, the ultrasonic assembly is also managed in sections. The ultrasonic parameter of each ultrasonic area is adjusted or not adjusted according to the temperature measurement of each temperature measurement area. The two factors make the adjustment of the ultrasonic parameter more accurate. In addition, since the center temperature sensor and the multiple edge temperature sensors are used, when each temperature sensor is effective, the reference temperature difference between the center and the edge is first calculated. If the center temperature sensor fails, the center temperature can be calculated and completed according to the real-time acquired edge temperature and the reference temperature difference. The center temperature is then used to participate in subsequent area temperature calculation and area ultrasonic parameter adjustment. The center temperature sensor does not need to be replaced during the process. It can be directly calculated and adjusted, which improves the efficiency of ultrasonic parameter adjustment. That is, the control method of the present application can alleviate the technical problems of inaccurate ultrasonic parameter adjustment and low adjustment efficiency of the current maxillofacial tumor hyperthermia system. BRIEF DESCRIPTION OF DRAWINGS

[0024] The technical solutions and other beneficial effects of the present application will become apparent from the following detailed description of the specific embodiments of the present application, combined with the accompanying drawings.

[0025] Figure 1 The scene schematic diagram of the ultrasonic parameter adjustment method provided by the embodiments of the present application.

[0026] Figure 2 The first flowchart of the ultrasonic parameter adjustment method provided by the embodiments of the present application.

[0027] Figure 3 Fig. 1 is a first partitioning schematic diagram of a temperature measuring assembly in an embodiment of the present application.

[0028] Figure 4 Fig. 2 is a partitioning schematic diagram of an ultrasonic assembly in an embodiment of the present application.

[0029] Figure 5 Fig. 3 is a second partitioning schematic diagram of a temperature measuring assembly in an embodiment of the present application.

[0030] Figure 6 Fig. 4 is a third partitioning schematic diagram of a temperature measuring assembly in an embodiment of the present application.

[0031] Figure 7 Fig. 5 is a second flow schematic diagram of an ultrasonic parameter adjustment method provided in an embodiment of the present application.

[0032] Figure 8 Fig. 6 is a structural schematic diagram of an ultrasonic parameter adjustment device provided in an embodiment of the present application.

[0033] Figure 9 Fig. 7 is a structural schematic diagram of an electronic device provided in an embodiment of the present application.

[0034] Legend of reference signs:

[0035] processing center 11; control center 12; ultrasonic assembly 13; circulating cooling system 14; temperature measuring assembly 15; body surface skin 21; maxillofacial tumor 22; first edge temperature sensor 1; second edge temperature sensor 2; third edge temperature sensor 3; fourth edge temperature sensor 4; center temperature sensor 5; fifth edge temperature sensor 6; sixth edge temperature sensor 7; temperature acquisition module 10; first calculation module 20; first monitoring module 30; second calculation module 40; second monitoring module 50; adjustment module 60; two-dimensional ultrasonic phased array 100; radio frequency circuit 101; memory 102; input unit 103; display unit 104; sensor 105; audio circuit 106; WiFi module 107; processor 108; power supply 109. DETAILED DESCRIPTION

[0036] The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, rather than all the embodiments. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative labor fall within the scope of protection of the present application.

[0037] Please refer to Figure 1 , Figure 1The scene diagram applied to the adjustment method of the ultrasonic parameter provided in the embodiments of the present application, the scene including a maxillofacial tumor hyperthermia system, the maxillofacial tumor hyperthermia system including a processing center 11, a control center 12, an ultrasonic assembly 13, a circulating cooling system 14, and a temperature measurement assembly 15. The ultrasonic assembly 13 includes an ultrasonic transducer, which operates under the control of the ultrasonic parameter, emits ultrasonic waves to perform hyperthermia on a maxillofacial tumor 22, and the circulating cooling system 14 is arranged between the ultrasonic assembly 13 and a body surface skin 21, and is used to carry away excess heat. The circulating cooling system 14 includes a flexible liquid bag, which can closely fit the two, so that the ultrasonic transducer can adapt to irregular maxillofacial. The temperature measurement assembly 15 punctures the maxillofacial tumor 22 and measures the temperature at the puncture position in real time during the hyperthermia process. The processing center 11 is used to acquire temperature data during the hyperthermia process and perform calculation, judgment, adjustment and other processing to obtain adjusted ultrasonic parameters. The control center 12 is used to receive the adjusted ultrasonic parameters and related instructions sent by the processing center 11, and control the ultrasonic assembly 13 to operate under the adjusted ultrasonic parameters. In the following embodiments, the process of how to adjust will be described in detail.

[0038] Please refer to Figure 2 , Figure 2 is the first flowchart of the adjustment method of the ultrasonic parameter provided in the embodiments of the present application, and the method specifically includes:

[0039] S1: acquiring a center temperature from a center temperature sensor in real time, and acquiring 2N edge temperatures from 2N edge temperature sensors in real time.

[0040] The maxillofacial tumor hyperthermia system includes the ultrasonic assembly 13 and the temperature measurement assembly 15, the temperature measurement assembly 15 including a center temperature sensor and N groups of edge temperature sensors, N being an integer not less than 2, the center temperature sensor being arranged corresponding to a tumor center, and each group of edge temperature sensors including two edge temperature sensors symmetrically arranged on both sides of the center temperature sensor. The temperature measurement assembly surrounds 2N temperature measurement areas, and each temperature measurement area is surrounded by two adjacent edge temperature sensors and the center temperature sensor. The ultrasonic assembly 13 includes 2N ultrasonic areas, and the 2N ultrasonic areas one-to-one cover the 2N temperature measurement areas.

[0041] As Figure 3As shown, taking N as 2 as an example, the temperature measuring assembly 15 includes a first edge temperature sensor 1, a second edge temperature sensor 2, a third edge temperature sensor 3, a fourth edge temperature sensor 4 and a center temperature sensor 5. The center temperature sensor 5 is arranged at the center of the maxillofacial tumor 22, and the other four edge temperature sensors are arranged at the edges of the maxillofacial tumor 22. Among them, the first edge temperature sensor 1 and the third edge temperature sensor 3 are a group of edge temperature sensors, which are symmetrically arranged on the left and right sides of the center temperature sensor 5; the second edge temperature sensor 2 and the fourth edge temperature sensor 4 are another group of edge temperature sensors, which are symmetrically arranged on the upper side and the lower side of the center temperature sensor 5.

[0042] The four edge temperature sensors and the center temperature sensor divide the entire hyperthermia area into four temperature measuring areas. Each two adjacent edge temperature sensors and the center temperature sensor serve as three vertices, and the area within the range of the three vertices forms a temperature measuring area. Figure 3 In the embodiment, the first edge temperature sensor 1, the second edge temperature sensor 2 and the center temperature sensor 5 form a first temperature measuring area ⊿125, the second edge temperature sensor 2, the third edge temperature sensor 3 and the center temperature sensor 5 form a second temperature measuring area ⊿235, the first edge temperature sensor 1, the fourth edge temperature sensor 4 and the center temperature sensor 5 form a third temperature measuring area ⊿145, and the third edge temperature sensor 3, the fourth edge temperature sensor 4 and the center temperature sensor 5 form a fourth temperature measuring area ⊿345.

[0043] As shown in FIG. 1, Figure 4 When N is 2, the ultrasonic assembly 13 includes four ultrasonic areas, namely a first ultrasonic area ⊿ABE, a second ultrasonic area ⊿BCE, a third ultrasonic area ⊿ADE and a fourth ultrasonic area ⊿CDE. The four ultrasonic areas one-to-one cover the four temperature measuring areas, that is, the first ultrasonic area ⊿ABE covers the first temperature measuring area ⊿125, the second ultrasonic area ⊿BCE covers the second temperature measuring area ⊿235, the third ultrasonic area ⊿ADE covers the third temperature measuring area ⊿145, and the fourth ultrasonic area ⊿CDE covers the fourth temperature measuring area ⊿345. The ultrasonic assembly 13 is provided with a two-dimensional ultrasonic phased array 100 in the ultrasonic area. Through the phased array, the ultrasonic parameters in any one ultrasonic area can be adjusted individually.

[0044] It should be noted that, when the temperature measuring area is determined, the line connecting the first edge temperature sensor 1 and the center temperature sensor 5 is a straight line, and the lines connecting the second edge temperature sensor 2 and the center temperature sensor 5, the first edge temperature sensor 1 and the second edge temperature sensor 2 are curves. This is because the overall shape of the ultrasonic emission area of the ultrasonic assembly 13 is circular or elliptical. This area division method can make the shape of the temperature measuring area match the shape of the ultrasonic area.

[0045] certainly, Figure 3 The location of the temperature measuring component 15 shown in FIG is only one example. According to the morphological distribution of the maxillofacial tumor 22 and the temperature measurement requirements, the location of each temperature sensor can also be arranged in other ways. For example, when N is 2, the location of the four edge temperature sensors can also be as follows: Figure 5 As shown, the first edge temperature sensor 1 and the third edge temperature sensor 3 are symmetrically arranged on the lower left and upper right sides of the central temperature sensor 5, and the second edge temperature sensor 2 and the fourth edge temperature sensor 4 are symmetrically arranged on the upper left and lower right sides of the central temperature sensor 5. For another example, when N is 3, the positions of the six edge temperature sensors can be as follows: Figure 6 As shown, the first edge temperature sensor 1 and the fourth edge temperature sensor 4 are symmetrically arranged on the lower left and upper right sides of the center temperature sensor 5, the second edge temperature sensor 2 and the fifth edge temperature sensor 6 are symmetrically arranged on the upper left and lower right sides of the center temperature sensor 5, and the third edge temperature sensor 3 and the sixth edge temperature sensor 7 are symmetrically arranged on the upper and lower sides of the center temperature sensor 5. Those skilled in the art can flexibly select and set the value of N and the position of each edge temperature sensor according to the actual scenario to meet the temperature measurement requirements in different situations. When the value of N is different and the position of each edge temperature sensor is different, the number and division of each ultrasonic region included in the ultrasonic component 13 also need to be adaptively changed accordingly to ensure that the two types of regions match.

[0046] In the above embodiments, the temperature measurement areas are preferably evenly distributed.

[0047] In this step, initial ultrasound parameters are set for the ultrasound component 13, and the ultrasound component 13 is controlled to operate with these initial ultrasound parameters, emitting ultrasound waves toward the maxillofacial tumor 22 for hyperthermia. After hyperthermia begins, the central temperature sensor measures the temperature at the center of the tumor in real time, while the edge temperature sensors measure the temperature at the edges of the tumor in real time. The measured central and edge temperatures are acquired in real time by the maxillofacial tumor hyperthermia system. The real-time measurement frequency can be 10 Hz.

[0048] S2: Calculate the reference temperature difference between the center and the edge based on the center temperature and 2N edge temperatures.

[0049] During hyperthermia, there is a temperature difference between the center and edge temperatures of approximately 2°C. However, this temperature difference can fluctuate dynamically depending on factors such as tumor morphology, individual patient differences, ultrasound parameters, and hyperthermia duration. Simply using a fixed value of 2 as the temperature difference can result in significant errors. Therefore, in this step, after acquiring the center temperature and 2N edge temperatures in real time, the reference temperature difference between the center and edge is calculated in real time.

[0050] In an embodiment, S2 specifically comprises:

[0051] S21: calculating a first temperature mean value of the 2N edge temperatures.

[0052] S22: determining the reference temperature difference of the center and the edge as the difference between the center temperature and the first temperature mean value.

[0053] The reference temperature difference is the difference between the center temperature and the edge temperature, and the mean value of all edge temperatures is used to participate in the calculation of the difference, which can make the calculation result of the reference temperature difference more accurate. As shown in Figure 3 , taking 2 as N for example, t1 represents the first edge temperature measured by the first edge temperature sensor 1 in real time, t2 represents the second edge temperature measured by the second edge temperature sensor 2 in real time, t3 represents the third edge temperature measured by the third edge temperature sensor 3 in real time, and t4 represents the fourth edge temperature measured by the fourth edge temperature sensor 4 in real time, and the first temperature mean value of the four is (t1+t2+t3+t4) / 4. t5 represents the center temperature measured by the center temperature sensor 5 in real time, and the reference temperature difference Δt=t5-(t1+t2+t3+t4) / 4.

[0054] S3: monitoring whether the center temperature sensor is failed in real time.

[0055] If the center temperature sensor is failed, it will cause the center temperature to be missing or wrong, which will affect the subsequent adjustment of the ultrasonic parameters. Therefore, this step needs to monitor whether the center temperature sensor is failed in real time.

[0056] S4: if not, calculating the region temperature of each temperature measurement region according to the two edge temperatures and the center temperature corresponding to each temperature measurement region; if yes, calculating the center temperature according to the 2N edge temperatures and the reference temperature difference obtained in real time, and calculating the region temperature of each temperature measurement region according to the two edge temperatures and the center temperature corresponding to each temperature measurement region.

[0057] If the monitoring result is that the center temperature sensor is not failed, it means that the accurate center temperature can be directly obtained from the center temperature sensor, and at this time, the two edge temperatures and the center temperature corresponding to each temperature measurement region can be directly calculated to obtain the region temperature of the corresponding temperature measurement region.

[0058] If the monitoring result is that the center temperature sensor is failed, it means that the accurate center temperature cannot be directly obtained from the center temperature sensor, and since the reference temperature difference of the center and the edge is calculated in real time in the foregoing step, when the center temperature is missing, the current missing center temperature can be inversely deduced by using the reference temperature value and the 2N edge temperatures obtained in real time, and then the two edge temperatures and the center temperature corresponding to each temperature measurement region can be calculated to obtain the region temperature of the corresponding temperature measurement region.

[0059] Since the area temperature of each temperature measuring area is simultaneously referenced to two edge temperatures and one center temperature, each area temperature can reflect the temperature condition of the current area as a whole, and the temperature measurement result is more referential relative to the single-point measurement mode. In addition, since the area temperature is calculated separately for each temperature measuring area, if there is uneven heat distribution, the unevenness can be intuitively reflected by different area temperatures, providing an effective reference for subsequent steps.

[0060] In an embodiment, S4 specifically comprises:

[0061] S41: calculating a second temperature mean of the 2N edge temperatures acquired in real time.

[0062] S42: determining the addition value of the second temperature mean and the reference temperature difference as the center temperature.

[0063] Similarly, using the mean of all edge temperatures to participate in the operation can make the calculation result of the center temperature more accurate. As shown in Figure 3 For example, taking N as 2, the second temperature mean of the 4 edge temperatures acquired in real time is (t1+t2+t3+t4) / 4, and the center temperature t5 calculated at this time is (t1+t2+t3+t4) / 4+Δt.

[0064] Since the temperatures measured by the temperature sensors are real-time changes, the reference temperature difference calculated at different times will also be different, and therefore the center temperature calculated according to the above formula is obtained by considering various dynamic change factors, and can better reflect the current real temperature of the center of the maxillofacial tumor, so that the temperature measurement result is more accurate.

[0065] In an embodiment, S4 specifically further comprises:

[0066] S43: calculating a third temperature mean of the two edge temperatures and the center temperature corresponding to each temperature measuring area.

[0067] S44: determining the third temperature mean as the area temperature of the corresponding temperature measuring area.

[0068] After the center temperature is directly measured or calculated, for each temperature measuring area, the third temperature mean of the three corresponding vertices is taken as the area temperature of the temperature measuring area, so that the calculated area temperature is higher than the edge temperature and lower than the center temperature, and is more referential. As shown in Figure 3As shown, taking N=2 as an example, the third temperature mean of the first temperature measurement region 125 is T1=(t1+t2+t5) / 3, the third temperature mean of the second temperature measurement region 235 is T2=(t2+t3+t5) / 3, the third temperature mean of the third temperature measurement region 145 is T3=(t1+t4+t5) / 3, and the third temperature mean of the fourth temperature measurement region 345 is T4=(t3+t4+t5) / 3.

[0069] S5: Real-time monitoring whether the target region temperature of the first target temperature measurement region exceeds the preset temperature range.

[0070] A preset temperature range is set for all temperature measurement regions. If the region temperature of each temperature measurement region is within the preset temperature range, it indicates that the overall temperature of each temperature measurement region is moderate, the center temperature is not too low, and the edge temperature is not too high. At this time, even if there is uneven heat distribution, it does not cause too much impact. If the region temperature of a certain temperature measurement region exceeds the preset temperature range, it indicates that the temperature measurement region may have a situation of too low center temperature or too high edge temperature. The former will make the maxillofacial tumor unable to be effectively thermally treated, and the latter will have the risk of damaging the edge tissue. In order to know these situations in time, it is necessary to monitor the region temperature of each temperature measurement region in real time to see whether the target region temperature of the first target temperature measurement region or some first target temperature measurement regions exceeds the preset temperature range.

[0071] In the embodiment, the preset temperature range is 37-45℃, and exceeding the preset temperature range means that the region temperature is lower than 37℃ or higher than 45℃. Further, considering that there may be fluctuations and errors within a certain range in the temperature measurement process, a margin, for example, 0.5℃, can also be set. If the region temperature is lower than 37-0.5=36.5℃ or higher than 45+0.5=45.5℃, it is also considered to exceed. Those skilled in the art can set a margin or no margin for judgment according to the needs.

[0072] S6: If yes, determining the ultrasound region covering the first target temperature measurement region as a target ultrasound region, adjusting the initial ultrasound parameter of the target ultrasound region to obtain a target ultrasound parameter of the target ultrasound region.

[0073] If the target region temperature of the first target temperature measurement region exceeds the preset temperature range, if the ultrasound assembly 13 continues to use the current ultrasound parameter to perform thermal treatment in the target ultrasound region covering the first target temperature measurement region, it will lead to the risk of maxillofacial tumor unable to be effectively thermally treated or damaging the edge tissue. At this time, the ultrasound parameter of the target ultrasound region needs to be adjusted to match the temperature exceeding situation of the first target temperature measurement region, so as to eliminate the risk of maxillofacial tumor unable to be effectively thermally treated or damaging the edge tissue. The adjusted ultrasound parameter is the target ultrasound parameter.

[0074] It should be noted that as hyperthermia treatment progresses, ultrasound parameter adjustments may be required more than once for a particular temperature measurement area. In this case, the initial ultrasound parameters for the target ultrasound area refer to the ultrasound parameters immediately prior to the current adjustment, and are not necessarily the ultrasound parameters set during the initial operation of the hyperthermia treatment system. Specifically, assuming that initial ultrasound parameters are set during the initial operation and become target ultrasound parameters after a single adjustment, if further adjustment is required, the target ultrasound parameters are used as the new initial ultrasound parameters and are then adjusted to obtain the new target ultrasound parameters.

[0075] If the temperatures in other zones fall within the preset temperature range, the temperatures in the other temperature measurement zones are moderate. The edge temperatures of these temperature measurement zones are not too high, thus preventing damage to peripheral tissue. At the same time, the core temperatures of these temperature measurement zones are not too low, ensuring a hyperthermia effect on the tumor. In this case, the initial ultrasound parameters for the ultrasound zones covering these temperature measurement zones do not need to be adjusted.

[0076] After adjusting or maintaining the initial ultrasound parameters of each ultrasound zone according to the aforementioned principles, the ultrasound assembly is controlled to operate at the adjusted target ultrasound parameters in the target ultrasound zone, while operating at the maintained initial ultrasound parameters in the other ultrasound zones. In this way, the regional temperature of the first target temperature measurement zone can be individually adjusted to ultimately fall within the preset temperature range, achieving a risk-free hyperthermia state, while the other temperature measurement zones continue to maintain a risk-free hyperthermia state.

[0077] like Figure 3 As shown, taking N as 2 as an example, assuming that the regional temperature of the third temperature measurement area ⊿145 is 46°C, which exceeds the preset temperature range, the third temperature measurement area ⊿145 is determined as the first target temperature measurement area, and the third ultrasonic area ⊿ADE is determined as the target ultrasonic area. Only the initial ultrasonic parameters of the third ultrasonic area ⊿ADE are adjusted to the target ultrasonic parameters, and the initial ultrasonic parameters of other ultrasonic areas are maintained to achieve zone adjustment.

[0078] In one embodiment, S6 specifically includes:

[0079] S61: If the target area temperature of the first target temperature measurement area exceeds the maximum value in the preset temperature range, the initial ultrasonic power of the target ultrasonic area is reduced to obtain the target ultrasonic power of the target ultrasonic area.

[0080] S62: If the target area temperature of the first target temperature measurement area is lower than the minimum value in the preset temperature range, the initial ultrasonic power of the target ultrasonic area is increased to obtain the target ultrasonic power of the target ultrasonic area.

[0081] The ultrasonic parameter refers to a parameter for controlling the operation of the ultrasonic assembly, and can specifically include an ultrasonic power. At different ultrasonic powers, the heat gathered by the ultrasonic transducer in the tumor is also different, and thus the temperature of each temperature measurement region can be adjusted by adjusting the ultrasonic power. If the target region temperature of the first target temperature measurement region exceeds the maximum value in the preset temperature range, it indicates that the target region temperature of the first target temperature measurement region is too high, and the ultrasonic energy in the region is too high. Therefore, the initial ultrasonic power of the target ultrasonic region needs to be reduced, so that the heat gathered by the ultrasonic energy is reduced, the region temperature is lowered, and the risk of damaging the edge tissue is reduced. Conversely, if the target region temperature of the first target temperature measurement region is lower than the minimum value in the preset temperature range, it indicates that the target region temperature of the first target temperature measurement region is too low, and the ultrasonic energy in the region is too low. Therefore, the initial ultrasonic power of the target ultrasonic region needs to be increased, so that the heat gathered by the ultrasonic energy is increased, the region temperature is raised, and the effectiveness of the hyperthermia treatment of the tumor center position is ensured.

[0082] When the ultrasonic power is adjusted, it can be achieved by adjusting the level of the ultrasonic power. For example, levels w1 to w10 are preset, and the higher the level, the greater the power value. In the initial state, the initial ultrasonic power is set to the w5 level. When a certain first target temperature measurement region needs to increase the ultrasonic power for the first time, the adjusted target ultrasonic power is the w6 level. When the ultrasonic power needs to be increased for the second time, the adjusted target ultrasonic power is the w7 level, and the subsequent levels are sequentially increased. When a certain first target temperature measurement region needs to reduce the ultrasonic power for the first time, the adjusted target ultrasonic power is the w4 level. When the ultrasonic power needs to be reduced for the second time, the adjusted target ultrasonic power is the w3 level, and the subsequent levels are sequentially reduced.

[0083] In an embodiment, S1 further includes, before S1:

[0084] Sa: Obtain CT / MRT data of the maxillofacial tumor.

[0085] Sb: Determine the partition parameters of the temperature measurement assembly and the ultrasonic assembly according to the CT / MRT data.

[0086] The partition parameter refers to a parameter related to region division, including positions of region vertexes and region boundary lines, etc. In the embodiment, CT / MRT data of the maxillofacial tumor can be acquired first, and a temperature measurement point-tissue mapping relationship can be established according to the data, and a physical shape position map of the maxillofacial tumor can be formed. According to the position map, the positions of the tumor center point and the tumor edge point can be accurately determined, and the partition parameters of the temperature measurement assembly and the ultrasonic assembly can be determined according to the connecting lines of the position points. Since how to divide each temperature measurement region and each ultrasonic region is closely related to the shape, size, distribution, etc. of the maxillofacial tumor, the position points determined by the CT / MRT data are relatively accurate, and the partition parameters determined based on the data can make the region division more reasonable, and finally the adjustment result of the ultrasonic parameters is also more accurate.

[0087] In an embodiment, S2 is followed by:

[0088] S7: Real-time monitoring whether any edge temperature sensor is invalid.

[0089] In addition to the center temperature sensor, the edge temperature sensor can also fail during use, resulting in the absence of a certain edge temperature, which in turn affects the subsequent adjustment of the ultrasonic parameters. Therefore, in addition to real-time monitoring whether the center temperature sensor is invalid, real-time monitoring whether any edge temperature sensor is invalid is also needed after S2.

[0090] S8: If yes, determining the temperature measurement region where the invalid edge temperature sensor is located as a second target temperature measurement region, calculating a fourth temperature average of the remaining one edge temperature and the center temperature corresponding to each second target temperature measurement region, and determining the fourth temperature average as the region temperature of the corresponding second target temperature measurement region.

[0091] If the monitoring result is that a certain edge temperature sensor is invalid, it means that the accurate edge temperature cannot be directly obtained from the edge temperature sensor, and the temperature measurement region where the edge temperature sensor is located has two, both of which are determined as the second target temperature measurement region. Each second target temperature measurement region still has two vertexes, which are the remaining one edge temperature and the center temperature. At this time, the fourth temperature average of the two can be calculated, and the fourth temperature average is determined as the region temperature of the second target temperature measurement region.

[0092] The region temperature of each temperature measurement region is originally the third temperature average of two edge temperatures and one center temperature. When a certain edge temperature is missing, the fourth temperature average of the remaining one edge temperature and the center temperature is used as the region temperature. Although one edge temperature is missing relative to other temperature measurement regions, the region temperature is still calculated by comprehensively considering the edge temperature and the center temperature. The region temperature is still higher than the edge temperature and lower than the center temperature, and still has strong reference value relative to the single-point temperature measurement method.

[0093] As Figure 3 shown, N is 2, assuming that the second edge temperature sensor 2 fails, the second edge temperature t2 is missing, the first temperature measurement area 125 and the second temperature measurement area 235 are both determined as the second target temperature measurement area, at this time, the area temperature of the first temperature measurement area 125 is T1=(t1+t5) / 2, the area temperature of the second temperature measurement area 235 is T2=(t3+t5) / 2, the area temperature of the third temperature measurement area 145 is still T3=(t1+t4+t5) / 3, and the area temperature of the fourth temperature measurement area 345 is still T4=(t3+t4+t5) / 3.

[0094] In an embodiment, after the step of monitoring the failure of any temperature sensor, further comprising:

[0095] S9: generating and reporting alarm information.

[0096] After monitoring the failure of any temperature sensor, in addition to using various algorithms to calculate the area temperature in different ways, corresponding alarm information needs to be generated and reported, so that relevant personnel can discover the failure of the temperature sensor in time and take appropriate measures to handle it in time.

[0097] As can be seen from the above embodiments, the ultrasonic parameter adjustment method provided by the present application simultaneously uses the temperatures measured by the center temperature sensor and the plurality of edge temperature sensors during temperature measurement, and adjusts the ultrasonic parameters based on the area temperature for real-time monitoring and adjustment, which can reduce the temperature measurement influence caused by uneven heat distribution compared with the method based on only the center temperature, and at the same time, the ultrasonic assembly is also managed in zones, and the ultrasonic parameters of each ultrasonic zone are adjusted or not adjusted according to the temperature measurement of each temperature measurement area, which comprehensively makes the adjustment of the ultrasonic parameters more accurate. In addition, since the center temperature sensor and the plurality of edge temperature sensors are used, when all the temperature sensors are effective, the reference temperature difference between the center and the edge is first calculated, if the center temperature sensor fails, the center temperature can be calculated and completed according to the real-time acquired edge temperature and the reference temperature difference, and the center temperature is used for subsequent area temperature calculation and area ultrasonic parameter adjustment, and the center temperature sensor does not need to be replaced during the process, and can be directly calculated and adjusted, so that the efficiency of the ultrasonic parameter adjustment is improved. That is, the control method of the present application can alleviate the technical problems of inaccurate ultrasonic parameter adjustment and low adjustment efficiency existing in the current maxillofacial tumor hyperthermia system.

[0098] As Figure 7 shown, Figure 7 is a second flow diagram of the ultrasonic parameter adjustment method provided by the present application, and the working process in the above embodiments will be described in the following. Figure 7 The working process in the above embodiments will be described in the following.

[0099] First, the ultrasonic transducer is operated at an initial ultrasonic power w5, the maxillofacial tumor is heated under ultrasonic irradiation, then the temperatures t1 to t5 of the central temperature sensor and the four edge temperature sensors are acquired in real time, the reference temperature difference Δt = t5-(t1+t2+t3+t4) / 4 is calculated in real time, and it is determined whether any temperature sensor is failed.

[0100] If yes, it is determined whether the central temperature sensor is failed or a certain edge temperature sensor is failed. If the central temperature sensor is failed, the central temperature t5 = (t1+t2+t3+t4) / 4+Δt is calculated first, and then the region temperatures of the four temperature measurement regions are calculated, which are T1=(t1+t2+t5) / 3, T2=(t2+t3+t5) / 3, T3=(t1+t4+t5) / 3, and T4=(t3+t4+t5) / 3 respectively. If a certain edge temperature sensor is failed (assuming that the second edge temperature sensor 2 is failed), the region temperatures of the four temperature measurement regions are directly calculated, which are T1=(t1+t5) / 2, T2=(t3+t5) / 2, T3=(t1+t4+t5) / 3, and T4=(t3+t4+t5) / 3 respectively.

[0101] If no, the region temperatures of the four temperature measurement regions are directly calculated, which are T1=(t1+t2+t5) / 3, T2=(t2+t3+t5) / 3, T3=(t1+t4+t5) / 3, and T4=(t3+t4+t5) / 3 respectively.

[0102] Then, it is determined whether there is a region temperature exceeding a preset temperature range among T1 to T4.

[0103] If yes, the initial ultrasonic power w5 of the target ultrasonic region corresponding to the temperature measurement region is adjusted, and w5 is increased by one level to w6 or decreased by one level to w4 as appropriate to obtain a target ultrasonic power, the ultrasonic regions corresponding to other temperature measurement regions maintain the initial ultrasonic power w5, the target ultrasonic region is operated at the target ultrasonic power w6 or w4, and other ultrasonic regions are operated at the initial ultrasonic power w5, and the process ends.

[0104] If no, the ultrasonic regions corresponding to all temperature measurement regions maintain the initial ultrasonic power w5 and are operated at w5, and the process ends.

[0105] Through the above process, the technical problems of inaccurate and low-efficiency ultrasonic parameter adjustment of the current maxillofacial tumor thermotherapy system can be alleviated.

[0106] On the basis of the method described in the above embodiment, this embodiment will be further described from the perspective of an ultrasonic parameter adjustment device, which is suitable for a maxillofacial tumor hyperthermia system, the maxillofacial tumor hyperthermia system comprising an ultrasonic assembly and a temperature measurement assembly, the temperature measurement assembly comprising a center temperature sensor and N groups of edge temperature sensors, N being an integer not less than 2, the center temperature sensor being arranged corresponding to a tumor center, each group of edge temperature sensors comprising two edge temperature sensors symmetrically arranged on both sides of the center temperature sensor, the temperature measurement assembly enclosing 2N temperature measurement regions, each of the temperature measurement regions being enclosed by two adjacent edge temperature sensors and the center temperature sensor, the ultrasonic assembly comprising 2N ultrasonic regions, the 2N ultrasonic regions one-to-one covering the 2N temperature measurement regions. Please refer to Figure 8 , the ultrasonic parameter adjustment device can comprise:

[0107] a temperature acquisition module 10, configured to acquire a center temperature in real time from the center temperature sensor and 2N edge temperatures in real time from the 2N edge temperature sensors;

[0108] a first calculation module 20, configured to calculate a reference temperature difference between the center and the edge according to the center temperature and the 2N edge temperatures;

[0109] a first monitoring module 30, configured to monitor whether the center temperature sensor is invalid in real time;

[0110] a second calculation module 40, configured to calculate a region temperature of a corresponding temperature measurement region according to two edge temperatures and a center temperature corresponding to each of the temperature measurement regions if the center temperature sensor is not invalid, and calculate a center temperature according to the 2N edge temperatures acquired in real time and the reference temperature difference, and calculate a region temperature of a corresponding temperature measurement region according to two edge temperatures and a center temperature corresponding to each of the temperature measurement regions if the center temperature sensor is invalid;

[0111] a second monitoring module 50, configured to monitor whether a target region temperature of a first target temperature measurement region exceeds a preset temperature range in real time;

[0112] an adjustment module 60, configured to determine an ultrasonic region covering the first target temperature measurement region as a target ultrasonic region, and adjust an initial ultrasonic parameter of the target ultrasonic region to obtain a target ultrasonic parameter of the target ultrasonic region if the target region temperature of the first target temperature measurement region exceeds the preset temperature range.

[0113] In an embodiment, the first calculation module 20 comprises:

[0114] a first calculation unit, configured to calculate a first temperature mean value of the 2N edge temperatures;

[0115] The first determining unit is configured to determine a difference between the center temperature and the first temperature mean value as a reference temperature difference between the center and the edge.

[0116] In an embodiment, the second calculating module 40 comprises:

[0117] The second calculating unit is configured to calculate a second temperature mean value of the 2N edge temperatures acquired in real time.

[0118] The second determining unit is configured to determine a sum of the second temperature mean value and the reference temperature difference as the center temperature.

[0119] In an embodiment, the second calculating module 40 further comprises:

[0120] The third calculating unit is configured to calculate a third temperature mean value of the two edge temperatures and the center temperature corresponding to each temperature measuring area.

[0121] The third determining unit is configured to determine the second temperature mean value as the area temperature of the corresponding temperature measuring area.

[0122] In an embodiment, the adjusting device of the ultrasonic parameters further comprises:

[0123] The third monitoring module is configured to monitor whether any of the edge temperature sensors is invalid in real time.

[0124] The third calculating module is configured to, if so, determine a temperature measuring area where the invalid edge temperature sensor is located as a second target temperature measuring area, calculate a fourth temperature mean value of the remaining one edge temperature and the center temperature corresponding to each second target temperature measuring area, and determine the fourth temperature mean value as the area temperature of the corresponding second target temperature measuring area.

[0125] In an embodiment, the initial ultrasonic parameters comprise an initial ultrasonic power, and the adjusting module 60 comprises:

[0126] The first obtaining unit is configured to, if the target area temperature of the first target temperature measuring area exceeds a maximum value in the preset temperature range, decrease the initial ultrasonic power of the target ultrasonic area to obtain a target ultrasonic power of the target ultrasonic area.

[0127] The second obtaining unit is configured to, if the target area temperature of the first target temperature measuring area is lower than a minimum value in the preset temperature range, increase the initial ultrasonic power of the target ultrasonic area to obtain a target ultrasonic power of the target ultrasonic area.

[0128] In an embodiment, the adjusting device of the ultrasonic parameters further comprises:

[0129] The data acquisition module is configured to acquire CT / MRT data of a maxillofacial tumor.

[0130] determining module configured to determine partition parameters of the temperature measuring assembly and the ultrasonic assembly according to the CT / MRT data.

[0131] Compared with the prior art, the ultrasonic parameter adjustment device provided in the application simultaneously uses the temperatures measured by the center temperature sensor and the plurality of edge temperature sensors during temperature measurement, and adjusts the ultrasonic parameters in real time based on the regional temperature, which can reduce the temperature measurement influence caused by uneven heat distribution compared with the prior art based on the center temperature only. In addition, the ultrasonic assembly is also managed in a partitioned manner, and the ultrasonic parameters of each ultrasonic region are adjusted or not adjusted according to the temperature measurement of each temperature measurement region, which comprehensively makes the adjustment of the ultrasonic parameters more accurate. In addition, since the center temperature sensor and the plurality of edge temperature sensors are used, when all the temperature sensors are effective, the reference temperature difference between the center and the edge is first calculated, if the center temperature sensor is invalid, the center temperature can be calculated and completed according to the real-time acquired edge temperature and the reference temperature difference, and the center temperature is used for subsequent regional temperature calculation and regional ultrasonic parameter adjustment, and the center temperature sensor does not need to be replaced during the process, but can be directly calculated and adjusted, which improves the efficiency of the ultrasonic parameter adjustment. That is, the application can alleviate the technical problems of inaccurate ultrasonic parameter adjustment and low adjustment efficiency of the current maxillofacial tumor hyperthermia system.

[0132] Correspondingly, the application also provides an electronic device, which can be arranged in a maxillofacial tumor hyperthermia system, the maxillofacial tumor hyperthermia system comprising an ultrasonic assembly and a temperature measuring assembly, the temperature measuring assembly comprising a center temperature sensor and N groups of edge temperature sensors, N being an integer not less than 2, the center temperature sensor being arranged corresponding to the center of a tumor, each group of edge temperature sensors comprising two edge temperature sensors symmetrically arranged on both sides of the center temperature sensor, the temperature measuring assembly enclosing 2N temperature measurement regions, each temperature measurement region being enclosed by two adjacent edge temperature sensors and the center temperature sensor, the ultrasonic assembly comprising 2N ultrasonic regions, the 2N ultrasonic regions covering the 2N temperature measurement regions one by one.

[0133] As shown in Figure 9 the electronic device can include a radio frequency (RF, Radio Frequency) circuit 101, a memory 102 including one or more computer readable storage media, an input unit 103, a display unit 104, a sensor 105, an audio circuit 106, a WiFi module 107, a processor 108 including one or more processing cores, and a power supply 109, etc. Those skilled in the art can understand that Figure 9The electronic device structure shown in the figure does not constitute a limitation on the electronic device, and can include more or fewer components than shown, or combine certain components, or arrange different components. Among them:

[0134] The radio frequency circuit 101 can be used for receiving and sending signals in the process of receiving or calling information, and in particular, receiving the downlink information of the base station and handing it over to one or more processors 108 for processing; in addition, sending data related to the uplink to the base station. The memory 102 can be used to store software programs and modules, and the processor 108 can execute various functional applications by running the software programs and modules stored in the memory 102. The input unit 103 can be used to receive input digital or character information, and generate keyboard, mouse, joystick, optical or trackball signal inputs related to customer settings and function control.

[0135] The display unit 104 can be used to display information input by the customer or information provided to the customer and various graphical customer interfaces of the server, which can be composed of graphics, text, icons, video and any combination thereof.

[0136] The electronic device can also include at least one sensor 105, such as a light sensor, a motion sensor, and other sensors. The audio circuit 106 includes a speaker, which can provide an audio interface between the customer and the electronic device.

[0137] WiFi belongs to wireless transmission technology, and the WiFi module 107 can help the customer to send and receive emails, browse web pages, and follow streaming media, etc., which provides the customer with wireless broadband Internet access. Although Figure 9 The WiFi module 107 is shown, but it is understood that it does not belong to the necessary structure of the electronic device, and can be omitted as needed without changing the essence of the application.

[0138] The processor 108 is the control center of the electronic device, which connects all parts of the mobile phone through various interfaces and lines, executes the software programs and / or modules stored in the memory 102, and calls the data stored in the memory 102, executes various functions and processes data of the electronic device, and thus monitors the whole mobile phone.

[0139] The electronic device also includes a power supply 109 (such as a battery) for supplying power to each component, and preferably, the power supply can be logically connected to the processor 108 through the power management system, so as to realize the functions of charge management, discharge management, and power consumption management through the power management system.

[0140] Although not shown, the electronic device can further include a camera, a Bluetooth module, etc., which are not described herein again. Specifically in the embodiment, the processor 108 in the server will load the executable file corresponding to the process of one or more than one application program into the memory 102 according to the following instructions, and run the application program stored in the memory 102 by the processor 108, so as to realize the following functions:

[0141] acquiring a center temperature in real time from the center temperature sensor and 2N edge temperatures in real time from the 2N edge temperature sensors;

[0142] calculating a reference temperature difference between the center and the edge according to the center temperature and the 2N edge temperatures;

[0143] monitoring whether the center temperature sensor is invalid in real time;

[0144] if not, calculating a region temperature of each temperature measurement region according to two edge temperatures and the center temperature corresponding to the temperature measurement region; and if yes, calculating the center temperature according to the 2N edge temperatures acquired in real time and the reference temperature difference, and calculating the region temperature of each temperature measurement region according to two edge temperatures and the center temperature corresponding to the temperature measurement region;

[0145] monitoring whether a target region temperature of a first target temperature measurement region exceeds a preset temperature range in real time;

[0146] if yes, determining an ultrasonic region covering the first target temperature measurement region as a target ultrasonic region, and adjusting an initial ultrasonic parameter of the target ultrasonic region to obtain a target ultrasonic parameter of the target ultrasonic region.

[0147] The electronic device provided in the application can alleviate the technical problems of inaccurate and low-efficiency ultrasonic parameter adjustment of the current maxillofacial tumor hyperthermia system.

[0148] In the above embodiments, the description of each embodiment has its own focus, and the parts not described in detail in a certain embodiment can be referred to the detailed description above, which will not be described herein again.

[0149] Those skilled in the art can understand that all or part of the steps in the various methods of the above embodiments can be completed by instructions, or by related hardware controlled by the instructions, which can be stored in a computer readable storage medium and loaded and executed by a processor.

[0150] To this end, an embodiment of the present application provides a computer readable storage medium, which can be arranged in a maxillofacial tumor hyperthermia system, the maxillofacial tumor hyperthermia system comprising an ultrasound assembly and a temperature measurement assembly, the temperature measurement assembly comprising a center temperature sensor and N sets of edge temperature sensors, N being an integer not less than 2, the center temperature sensor being arranged corresponding to a tumor center, each set of edge temperature sensors comprising two edge temperature sensors symmetrically arranged on both sides of the center temperature sensor, the temperature measurement assembly enclosing 2N temperature measurement regions, each of the temperature measurement regions being enclosed by two adjacent edge temperature sensors and the center temperature sensor, and the ultrasound assembly comprising 2N ultrasound regions, the 2N ultrasound regions covering the 2N temperature measurement regions one by one.

[0151] The computer readable storage medium stores a plurality of instructions, which can be loaded by a processor to implement the following functions:

[0152] Real-time acquisition of a center temperature from the center temperature sensor and real-time acquisition of 2N edge temperatures from the 2N edge temperature sensors;

[0153] Calculation of a reference temperature difference between the center and the edges according to the center temperature and the 2N edge temperatures;

[0154] Real-time monitoring of whether the center temperature sensor is invalid;

[0155] If not, calculation of a region temperature of each temperature measurement region according to two edge temperatures and a center temperature corresponding to the temperature measurement region; if yes, calculation of a center temperature according to the 2N edge temperatures and the reference temperature difference, and calculation of a region temperature of each temperature measurement region according to two edge temperatures and a center temperature corresponding to the temperature measurement region;

[0156] Real-time monitoring of whether a target region temperature of a first target temperature measurement region exceeds a preset temperature range;

[0157] If yes, determination of an ultrasound region covering the first target temperature measurement region as a target ultrasound region, adjustment of an initial ultrasound parameter of the target ultrasound region, and obtaining of a target ultrasound parameter of the target ultrasound region.

[0158] The computer readable storage medium provided by the present application can alleviate the technical problems of inaccurate and low-efficiency ultrasound parameter adjustment of the current maxillofacial tumor hyperthermia system.

[0159] The above describes in detail the method and device for adjusting an ultrasonic parameter, the electronic device and the computer readable storage medium provided by the embodiments of the present application. The principles and implementation manners of the present application are described by applying specific examples. The above description of the embodiments is only used to help understand the technical solutions of the present application and the core ideas thereof. Those skilled in the art should understand that the technical solutions recorded in the foregoing embodiments can be modified, or some technical features thereof can be replaced equivalently, and the modifications or replacements do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of the present application.

Claims

1. An apparatus for adjusting an ultrasonic parameter, characterized by The device is suitable for a maxillofacial tumor hyperthermia system, the maxillofacial tumor hyperthermia system comprising an ultrasonic assembly and a temperature measurement assembly, the temperature measurement assembly comprising a center temperature sensor and N groups of edge temperature sensors, N being an integer not less than 2, the center temperature sensor being arranged corresponding to a tumor center, each group of edge temperature sensors comprising two edge temperature sensors symmetrically arranged on two sides of the center temperature sensor, the temperature measurement assembly enclosing 2N temperature measurement regions, each of the temperature measurement regions being enclosed by two adjacent edge temperature sensors and the center temperature sensor, the ultrasonic assembly comprising 2N ultrasonic regions, the 2N ultrasonic regions covering the 2N temperature measurement regions one by one, the device comprising: a temperature acquisition module configured to acquire a center temperature from the center temperature sensor and 2N edge temperatures from the 2N edge temperature sensors in real time; a first calculation module configured to calculate a reference temperature difference between the center and the edge according to the center temperature and the 2N edge temperatures, the first calculation module comprising a first calculation unit and a first determination unit, the first calculation unit being configured to calculate a first temperature mean value of the 2N edge temperatures, and the first determination unit being configured to determine a difference between the center temperature and the first temperature mean value as the reference temperature difference between the center and the edge; a first monitoring module configured to monitor whether the center temperature sensor is invalid in real time; a second calculation module configured to, if not, calculate a region temperature of a corresponding temperature measurement region according to two edge temperatures and a center temperature corresponding to each of the temperature measurement regions, and if yes, calculate a center temperature according to the reference temperature difference and the 2N edge temperatures acquired in real time, and calculate a region temperature of a corresponding temperature measurement region according to two edge temperatures and a center temperature corresponding to each of the temperature measurement regions, the second calculation module comprising a second calculation unit and a second determination unit, the second calculation unit being configured to calculate a second temperature mean value of the 2N edge temperatures acquired in real time, and the second determination unit being configured to determine a sum of the second temperature mean value and the reference temperature difference as the center temperature; a second monitoring module configured to monitor whether a target region temperature of a first target temperature measurement region exceeds a preset temperature range in real time; an adjustment module configured to, if yes, determine an ultrasonic region covering the first target temperature measurement region as a target ultrasonic region, and adjust an initial ultrasonic parameter of the target ultrasonic region to obtain a target ultrasonic parameter of the target ultrasonic region.

2. The apparatus for adjusting an ultrasound parameter according to claim 1, wherein, The second calculation module further comprises: a third calculation unit configured to calculate a third temperature mean value of two edge temperatures and a center temperature corresponding to each of the temperature measurement regions; a third determination unit configured to determine the second temperature mean value as a region temperature of a corresponding temperature measurement region.

3. The apparatus for adjusting an ultrasound parameter according to claim 1, wherein, The device further comprises: a third monitoring module configured to monitor whether any of the edge temperature sensors is invalid in real time. The third calculation module is configured to: if so, determine a temperature measuring area where the failed edge temperature sensor is located as a second target temperature measuring area; calculate a fourth temperature average of the remaining one edge temperature and the center temperature corresponding to each second target temperature measuring area; and determine the fourth temperature average as a region temperature of the corresponding second target temperature measuring area.

4. The apparatus for adjusting an ultrasonic parameter according to claim 1, wherein, The initial ultrasonic parameters include an initial ultrasonic power, and the adjusting module includes: A first obtaining unit is configured to: if a target region temperature of a first target temperature measuring area exceeds a maximum value in a preset temperature range, reduce the initial ultrasonic power of the target ultrasonic region to obtain a target ultrasonic power of the target ultrasonic region. A second obtaining unit is configured to: if the target region temperature of the first target temperature measuring area is lower than a minimum value in the preset temperature range, increase the initial ultrasonic power of the target ultrasonic region to obtain the target ultrasonic power of the target ultrasonic region.

5. The apparatus for adjusting an ultrasound parameter according to any one of claims 1 to 4, characterized in that, The device further includes: A data acquisition module is configured to acquire CT / MRT data of a maxillofacial tumor; A determination module is configured to determine partition parameters of the temperature measuring assembly and the ultrasonic assembly according to the CT / MRT data.

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