Closing instrument with attaching and capturing device

Abstract

The invention relates to the field of medical instruments, in particular to a closing instrument with a fitting and capturing device, the closing instrument is used for closing a channel between first tissue and second tissue and comprises a loading tube, a puncture assembly and the fitting and capturing device, and the fitting and capturing device comprises a controllable guide part, a compliance supporting part, a connecting part and a capturing part. The controllable guiding piece is connected with the far-end part of the loading tube, and the controllable guiding piece is used for being attached to first tissue; moreover, the compliant supporting piece is attached to the second tissue and deforms according to the shape of the second tissue, and when the puncture assembly punctures the second tissue, the puncture assembly penetrates through the capturing piece connected with the compliant supporting piece.

Description

Technical Field

[0001] The present application relates to the field of medical devices, and in particular to a closing device with a fitting capture device. Background Art

[0002] The foramen ovale is a fissure located at the junction of the septum primum and septum secundum of the atrial septum. It forms during embryonic development and provides a blood supply to the heart. After birth, this blood supply changes, and the foramen ovale closes naturally. If the foramen ovale has not closed by age three, it is called a patent foramen ovale, which affects approximately 25% of the population. In recent years, with the continued advancement of research on the foramen ovale, the various clinical syndromes associated with it have received increasing attention, including cryptogenic stroke, transient ischemic attack, migraine, recumbent-orthostatic hypoxemia, sleep apnea syndrome, myocardial infarction with normal coronary arteries, and neurodecompression sickness. Cryptogenic stroke and migraine, in particular, not only cause significant physical and emotional distress to patients, but also place a heavy burden on families and society.

[0003] Common treatments for patent foramen ovale include implanting a double-disc structure or suturing the patent channel. However, since a large piece of non-decomposable device will remain in the heart after the occlusion disc is implanted, it is not conducive to the patient's recovery and will affect other surgical treatments. Therefore, suturing is often recommended clinically.

[0004] Patent 202211628104.8 discloses a tissue closure device comprising a delivery catheter, an implant for closing tissue defects, and a guide mechanism, a puncture mechanism, and a positioning mechanism disposed within the delivery catheter. The positioning mechanism can provide support for the puncture mechanism as it punctures the tissue to be closed. However, this solution has the following drawbacks: First, the positioning mechanism supports the secondary septum and the primary septum through both the upper and lower regions. However, since the upper and lower regions cannot provide support independently, when the lower region is adjusted to support the primary septum, the upper region deflects simultaneously, affecting the position of the bending section on the secondary septum, affecting the second puncture effect while pulling on the first puncture area, thereby enlarging the hole in the secondary septum. Second, the positioning bracket and the clamp require at least two tubes for delivery. This design increases the size of the delivery system and is not conducive to the patient's subsequent recovery. Third, since the primary septum tissue is thin, pulling the proximal end of the implant will cause the weak primary septum to be pulled upward, which, after being torn, results in poor sealing effect.

[0005] In summary, the existing technology has the following problems that need to be urgently solved: First, when puncturing the second tissue in the existing technology, it will affect the puncture point of the first tissue and cause the puncture tube to shake or move; second, in order to clamp the first tissue and the second tissue in the existing technology, two tubes are needed to control the clamping parts, resulting in an increase in the diameter of the delivery catheter; third, when closing the two pieces of tissue to be closed, the second tissue will be pulled, causing the second tissue to tear and affecting the blocking effect. Summary of the Invention

[0006] This application is proposed in view of the above and other more concepts.

[0007] One of the purposes of this application is to overcome the shortcomings of the existing technology. In order to address the problems in the existing technology that the puncture instrument affects the puncture effect of the first tissue and the stability of the puncture tube when puncturing the second tissue, the problem of setting two or more tubes to control the clamping parts, which causes the size of the delivery tube to be expanded, and the problem that the sealing effect is affected after the tissue to be closed is torn, a closing device with a fitting capture device is provided.

[0008] The object of the present invention is achieved through the following solutions: A closing device with a fitting capture device is used to close a channel between a first tissue and a second tissue, comprising a loading tube, a puncture assembly and a fitting capture device, wherein the fitting capture device comprises a controllable guide, a compliant support, a connecting member and a capturing member, wherein the controllable guide is connected to the distal end portion of the loading tube, and the controllable guide is used to fit the first tissue; and the compliant support fits the second tissue and deforms to conform to the shape of the second tissue, and when the puncture assembly punctures the second tissue, the puncture assembly passes through the capturing member connected to the compliant support.

[0009] The purpose of the present invention can be further achieved by the following technical solutions: In one embodiment, a closing member is pre-installed in the puncture assembly, and the closing member passes through the first tissue and the second tissue; and the closing member is connected to the capturing member after the puncture assembly passes through the second tissue.

[0010] In one embodiment, the closure comprises a flexible wire and a restraint.

[0011] In one embodiment, the capture member is detachably connected to the compliant support member, and the capture member is retained in the target position together with the closing member; the capture member is in contact with the proximal surface of the second tissue.

[0012] In one embodiment, the constraint is delivered to the proximal face of the capture member and the flexible wire is passed through the second tissue.

[0013] In one embodiment, the first tissue is secondary septal tissue, and the second tissue is primary septal tissue.

[0014] In one embodiment, the capture element is made of a polymer material with a high degree of endothelialization.

[0015] In one embodiment, the capture member includes a capture body and a connecting coil.

[0016] In one embodiment, the conforming capture device includes a control line, and a plurality of through holes are provided on the compliant support member, through which the connecting coil passes, and the control line passes through the connecting coil, thereby forming a detachable connection.

[0017] In one embodiment, the capturing member is fixedly connected to the compliant support member, and operation of the conforming capturing device drives the capturing member and the closing member to move proximally; the portion of the closing member that passes through the second tissue and the portion of the closing member that does not pass through the first tissue form a connection inside or outside the body, and the closing member forms a closed loop after passing through the first tissue and the second tissue.

[0018] In one embodiment, the capture member and the compliant support structure are connected by weaving, welding or gluing.

[0019] In one embodiment, the capturing member is a polyester cloth strip.

[0020] In one embodiment, the connecting member is connected to the controllable guide member and the compliant support member, and the free end of the controllable guide member is facing in the distal direction, and the free end of the compliant support member is facing in the proximal direction. When the compliant support member is in contact with the second tissue, it provides supporting force for the puncture assembly; and the controllable guide member and the compliant support member are arranged opposite to each other on the circumference.

[0021] In one embodiment, when the compliant support member is in contact with the second tissue, its shape is adapted to the second tissue, and the compliant support member includes a plurality of support rods, and the plurality of support rods form a three-dimensional support surface; and when the compliant support member is in contact with the second tissue, different support rods are deformed to different degrees.

[0022] In one embodiment, the support rod includes an arc portion, a supporting portion and a retaining portion; and the arc portion is connected to the connecting member, the supporting portion provides a supporting area for the second tissue, and the retaining portion is located in the proximal direction of the connecting member in a natural state.

[0023] In one embodiment, when the fitting capture device is pre-installed, the arc portion, the supporting portion and the retaining portion are arranged from the proximal end to the distal end.

[0024] In one embodiment, it also includes a pushing tube and a leading component, the fitting capture device is connected to the pushing tube, and the pushing tube is sleeved in the leading component; and the compliant support member also includes an adjustment part, the adjustment part is connected to the retaining part, and the adjustment part is sleeved outside the pushing tube.

[0025] In another embodiment, when the fitting capture device is pre-installed, the arc portion, the supporting portion and the retaining portion are arranged from the distal end to the proximal end.

[0026] In one embodiment, the leading member enters the lesion first, and the pushing tube enters the foramen ovale tissue along the leading member.

[0027] In one embodiment, the position of the adjustment portion relative to the push tube is changed to change the shape of the compliant support member, thereby changing the moving distance of the second tissue driven by the compliant support member.

[0028] In one embodiment, the loading tube is used to deliver the puncture assembly; the puncture assembly includes a first puncture tube and a second puncture tube arranged in the first puncture tube; the first puncture tube includes a first curved tube and a second curved tube arranged in the first curved tube and connected to the first curved tube; the first curved tube and the second curved tube are bent in a natural state, the first curved tube includes a first rib arranged on the small curve side, and the second curved tube includes a second rib arranged on the large curve side.

[0029] In one embodiment, when puncturing the first tissue, the distal end of the second puncture tube extends beyond the first puncture tube, and the second puncture tube and the first puncture tube pass through the first tissue in sequence.

[0030] In one embodiment, the second puncture tube is pre-installed in the second curved tube, and the second rib supports the second puncture tube when the second puncture tube reciprocates.

[0031] In one embodiment, the second rib supports the second puncture tube when the second puncture tube moves forward, and the first rib supports the second puncture tube when the second puncture tube moves backward.

[0032] In one embodiment, the controllable guide member includes an elastic guide portion and a control portion, and the control portion is pulled to change the swing angle of the elastic guide portion; and the elastic guide portion also includes a limiting opening, and the distal end of the loading tube is arranged in the limiting opening.

[0033] In one embodiment, in a natural state, the elastic guide portion remains parallel to the center line of the connector.

[0034] In one embodiment, when the control portion is pulled, the elastic guide portion swings toward the proximal end.

[0035] Compared with the prior art, the advantages of the technical solution of this application include at least the following: 1. In the prior art, in order to support the puncture assembly during puncture, a positioning bracket is used to support the secondary septum and the primary septum. However, when puncturing the primary septum, adjusting the positioning bracket will change the relative position of the positioning bracket and the secondary septum, thereby pulling the secondary septum and enlarging the puncture hole on the secondary septum, causing secondary damage. Moreover, since the closing member locks the secondary septum and the primary septum by pulling the proximal end of the closing member, such pulling will cause the primary septum to be subjected to an upward force that violates the natural shape of the heart. In addition, the primary septum itself is very thin, and the primary septum tissue is easily damaged, or the puncture hole on the primary septum is enlarged. The present application solves the above problems. First, the present application designs a fitting capture device, which includes a fitting capture device that supports the secondary septum. The controllable guide member and the compliant support member supporting the primary septum are relatively independent. When the primary septum is punctured, the controllable guide member remains stationary, avoiding the problem that the second puncture affects the effect of the first puncture. Secondly, the conformable capture device of the present application is also provided with a capture member. When the puncture assembly punctures the primary septum, it will pass through the capture member, so that the closing member will be connected to the capture member. The capture member can remain in the lesion together with the closing member. Since the capture member has a certain area, the hole on the primary septum can be blocked even if it is enlarged. Alternatively, the capture member pulls the closing member toward the proximal end and forms a connection outside the patient's body or body. The closing member realizes a closed loop at the lesion. During this process, the primary septum will not be subjected to an upward force, and the damage to the tissue is small.

[0036] 2. Different from the prior art, the compliant support member of the present application includes an arc portion, a supporting portion and a retaining portion. The arc portion is connected to the connecting member. On the one hand, it ensures that the compliant support member can smoothly enter the lesion along with the pushing tube, and on the other hand, it can obtain the supporting force of the connecting member to ensure that the supporting portion will not be excessively deformed when fitting the primary septum; the supporting portion does not need to directly contact the pushing tube, thereby maintaining a certain gap between the supporting portion and the pushing tube, and can push the primary septum toward the left atrium, reducing the activity space of the primary septum, facilitating the restriction of the primary septum, and at the same time, the supporting portion supporting the primary septum will not affect any progress of the secondary septum during the operation; the retaining portion provides supporting force at the proximal position, so that both ends of the supporting portion can obtain supporting force, ensuring the fitting effect of the supporting portion and the primary septum, and facilitating the second puncture.

[0037] 3. Different from the prior art, the capture member of the present application is detachably connected to the compliant support member. After the capture member and the constraint are connected, they will adhere to the primary septum tissue for a long time. Therefore, the conforming capture device not only realizes the function of supporting the primary septum for puncture, but also can implant the capture member to fit the puncture hole to prevent bleeding. The structural design is ingenious. Moreover, the capture member is made of polyester cloth, elastic membrane cloth or degradable material, which will not affect the secondary puncture of the atrial septum in the later stage.

[0038] 4. Different from the prior art, the capture member and the compliant support member of the present application are fixedly connected, and the closing member is connected to the capture member after puncturing the septum secundum. Therefore, pulling the conforming capture device can pull the flexible line that passes through the septum secundum and is located on the right atrial surface. The closing member can form a closed loop connection at other locations inside the heart or outside the patient's body, causing less damage to the foramen ovale tissue.

[0039] 5. Different from the existing technology, the conformable capture device is connected to the push tube. By pushing a push tube, the controllable guide and the compliant support can be transported to the target position. The space efficiency of the tube is high, which facilitates access to the target position.

[0040] 6. Different from the prior art, the compliant support also includes an adjustment portion. The adjustment portion slides relative to the push tube to change the shape of the compliant support connected to the adjustment portion. Pushing the adjustment portion toward the distal end can cause the support portion to arch further toward the left atrium, pushing the septum secundum to the roof of the left atrium. As a result, the activity space of the septum secundum is limited and is supported by the support portion, making it easier for the second puncture tube to pass through the septum secundum tissue. The puncture effect is good and it can adapt to foramen ovale tissues of different shapes, which has great clinical significance.

[0041] The embodiments of the present application can achieve other advantageous technical effects that are not listed one by one. These other technical effects may be partially described below; and they can be anticipated and understood by those skilled in the art after reading this application. BRIEF DESCRIPTION OF THE DRAWINGS

[0042] The above features and advantages of these embodiments and other features and advantages and the manner in which they are achieved will become more apparent and the embodiments of the present application can be better understood by referring to the following description in conjunction with the accompanying drawings, in which: Figure 1 Schematic diagram of the overall structure of the closure device of the present invention.

[0043] Figure 2 and Figure 3 It is a schematic structural diagram of the bonding capture device of the present invention.

[0044] Figure 4 This is a schematic diagram of the pre-assembly of the bonding capture device of the present invention.

[0045] Figure 5 and Figure 6Schematic diagram of the structure of the puncture assembly of the present invention.

[0046] Figures 7 to 12 Schematic diagram of the operating steps of the present invention.

[0047] Figures 13 to 18 This is another embodiment of the present invention.

[0048] Figures 19 to 22 This is another embodiment of the present invention.

[0049] The features indicated by the numbers in the accompanying drawings are as follows: 1-first tissue, 2-second tissue, 3-loading tube, 4-puncture assembly, 41-first puncture tube, 411-first curved tube, 412-second curved tube, 413-first rib, 414-first slit, 415-second rib, 416-second slit, 42-second puncture tube, 5-fitting capture device, 51-controllable guide, 511-elastic guide part, 512-control part, 513-limiting mouth, 52-compliant support member, 521-support rod, 5211-arc part, 5212-support part, 5213-holding part, 5214-adjustment part, 522-through hole, 53-connecting member, 54-capturing member, 541-capturing body, 542-connecting coil, 6-advanced member, 61-transition structure, 7-pushing tube, 71-separation wire member, 8-closing member, 81-flexible line, 82-restraint, 9-delivery tube, 91-control line. DETAILED DESCRIPTION

[0050] In the following description of the drawings and specific embodiments, details of one or more embodiments of the present application will be described. Other features, purposes and advantages of the present application will be clear from these descriptions, drawings and claims.

[0051] It should be understood that the phrases and terms used herein are for descriptive purposes only and should not be considered restrictive. The use of "include," "comprise," or "have" and variations thereof herein is intended to encompass the items listed thereafter and their equivalents as well as additional items.

[0052] The present application will be described in more detail below with reference to different embodiments and examples of several aspects of the application.

[0053] In the present application, the term “proximal end” or “proximal side” refers to an end or side closer to a surgical operator, and “distal end” or “distal side” refers to an end or side farther from a surgical operator. Example 1

[0054] like Figure 1 and Figure 2As shown, when the present invention is used to close the foramen ovale tissue, a closing device with a fitting capture device according to an embodiment of the present application is illustrated, which is used to close the channel between the first tissue 1 and the second tissue 2, including a loading tube 3, a puncture assembly 4 and a fitting capture device 5, wherein the fitting capture device 5 includes a controllable guide 51, a compliant support 52, a connecting member 53 and a capturing member 54, wherein the controllable guide 51 is connected to the distal end of the loading tube 3, and the controllable guide 51 is used to fit the first tissue 1; and the compliant support 52 fits the second tissue 2 and deforms to conform to the shape of the second tissue 2, and when the puncture assembly 4 punctures the second tissue 2, the puncture assembly 4 passes through the capturing member 54 connected to the compliant support 52, as shown in FIG. Figure 9 shown.

[0055] In the first embodiment, the puncture assembly 4 is pre-installed with a closing member 8, which passes through the first tissue 1 and the second tissue 2; and the closing member 8 is connected to the capturing member 54 after the puncture assembly 4 passes through the second tissue 2.

[0056] In the first embodiment, the controllable guiding member 51 , the compliant supporting member 52 and the connecting member 53 are integrally connected.

[0057] In the first embodiment, the closing member 8 includes a flexible line 81 and a restraint 82. Figure 6 As shown, the constraint 82 is delivered to the proximal end surface of the capture member 54 , and the flexible wire 81 passes through the second tissue 2 .

[0058] In the first embodiment, the capturing member 54 is detachably connected to the compliant support member 52 , and the capturing member 54 and the closing member 8 remain at the target position; the capturing member 54 is in contact with the proximal surface of the second tissue 2 .

[0059] In the first embodiment, the first tissue 1 is a secondary septal tissue, and the second tissue 2 is a primary septal tissue.

[0060] In the first embodiment, the capture member 54 includes a capture body 541 and a connecting coil 542, the conforming capture device 5 includes a control line 91, and a plurality of through holes 522 are provided on the conforming support member 52. The connecting coil 542 passes through the through holes 522, and the control line 91 passes through the connecting coil 542, thereby forming a detachable connection. Figure 3 shown.

[0061] In the first embodiment, the connecting member 53 is connected to the controllable guide member 51 and the compliant support member 52, and the free end of the controllable guide member 51 faces the distal direction, and the free end of the compliant support member 52 faces the proximal direction. Figure 2 As shown, the compliant support member 52 provides support force for the puncture assembly 4 when it is in contact with the second tissue 2; and the controllable guide member 51 and the compliant support member 52 are arranged opposite to each other on the circumference.

[0062] In the first embodiment of the present invention, when the compliant support member 52 is in contact with the second tissue 2, its shape is adapted to the second tissue 2. The compliant support member 52 includes a plurality of support rods 521, and the plurality of support rods 521 form a three-dimensional support surface. Moreover, when the compliant support member 52 is in contact with the second tissue 2, different support rods 521 deform to different degrees.

[0063] In this embodiment 1, the support rod 521 includes an arc portion 5211, a support portion 5212 and a retaining portion 5213; and, the arc portion 5211 is connected to the connecting member 53, the support portion 5212 provides a support area for the second tissue 2, and the retaining portion 5213 is naturally located in the proximal direction of the connecting member 53.

[0064] In the first embodiment, when the fitting capture device 5 is pre-assembled, the arc portion 5211, the support portion 5212 and the retaining portion 5213 are arranged from the proximal end to the distal end. Figure 4 shown.

[0065] In the first embodiment, the controllable guide member 51 includes an elastic guide portion 511 and a control portion 512, and the control portion 512 is pulled to change the swing angle of the elastic guide portion 511; and the elastic guide portion 511 also includes a limiting opening 513, and the distal end of the loading tube 3 is arranged in the limiting opening 513.

[0066] In the first embodiment, the control portion 512 is pulled, and the elastic guide portion 511 swings toward the proximal end.

[0067] In the first embodiment, a push tube 7 and a leading component 6 are further included. The fitting capture device 5 is connected to the push tube 7 , and the push tube 7 is sleeved inside the leading component 6 .

[0068] In the first embodiment, the leading member 6 enters the lesion first, and the pushing tube 7 enters the foramen ovale tissue along the leading member 6 .

[0069] In the first embodiment, the loading tube 3 is used to deliver the puncture assembly 4; the puncture assembly 4 includes a first puncture tube 41 and a second puncture tube 42 arranged in the first puncture tube 41; the first puncture tube 41 includes a first curved tube 411 and a second curved tube 412 arranged in the first curved tube 411 and connected to the first curved tube 411; the first curved tube 411 and the second curved tube 412 are naturally curved, the first curved tube 411 includes a first rib 413 arranged on the small curved side, and the second curved tube 412 includes a second rib 415 arranged on the large curved side. Figure 5 shown.

[0070] In the first embodiment, when the first tissue 1 is punctured, the distal end of the second puncture tube 42 exceeds the first puncture tube 41, and the second puncture tube 42 and the first puncture tube 41 pass through the first tissue 1 in sequence. Figure 9 shown.

[0071] In the first embodiment, the first curved tube 411 further includes a first slit 414 disposed opposite to the first rib 413, and the second curved tube 412 further includes a second slit 416 disposed opposite to the second rib 415. Figure 5 shown.

[0072] In the first embodiment, the second puncture tube 42 is pre-installed in the second curved tube 412 , and the second rib 415 supports the second puncture tube 42 when the second puncture tube 42 reciprocates.

[0073] In the first embodiment, the second rib 415 supports the second puncture tube 42 when the second puncture tube 42 moves forward, and the first rib 413 supports the second puncture tube 42 when the second puncture tube 42 moves backward.

[0074] In the first embodiment, a delivery tube 9 is further included, and the push tube 7 and the puncture assembly 4 are both pre-installed in the delivery tube 9 .

[0075] In the first embodiment, the capturing member 54 is made of polyester cloth.

[0076] The exemplary operation process of inserting the closure device of the first embodiment is as follows: (1) Establish a PFO access channel, reserve a guide member 6, ensure that the distal end of the guide member 6 is in the left atrium, and then push the push tube 7 along the guide member 6 through the femoral vein into the right atrium, and then push it to the patent foramen ovale between the secondary septum and the primary septum near the atrial septum; (2) Retract the delivery tube 9 to expose the fitting capture device 5, pull the control member to swing the elastic guide 511 toward the right atrium, push the push tube 7 to move distally, and confine the secondary septum tissue between the elastic guide 511 and the leading member 6. At this time, the compliant support member 52 also pushes the primary septum to move toward the left atrium, and the support portion 5212 supports the primary septum tissue. Figure 7 As shown; (3) The loading tube 3 is moved toward the distal end, and the loading tube 3 is attached to the secondary septum, as shown in FIG. Figure 8 As shown; (4) Operate the second puncture tube 42 to move its end slightly beyond the first puncture tube 41, and perform the first puncture. The second puncture tube 42 and the first puncture tube 41 pass through the secondary septum in sequence. Figure 9 As shown; (5) Retract the second puncture tube 42 into the first puncture tube 41, push the first puncture tube 41 toward the distal end, and push the second bending tube 412 to make the first puncture tube 41 bend, as shown in FIG. Figure 10 As shown; (6) The first puncture tube 41 is placed against the distal end of the primary septum, and the second puncture tube 42 is operated to perform puncture. Figure 11 As shown, the closing member 8 is released, the constraint 82 is separated from the second puncture tube 42 and connected to the capture member 54, and the flexible wire 81 passes through the capture member 54 and the primary septum tissue.

[0077] (7) Pull the control line 91 to separate the compliant support member 52 from the capture member 54 and reclaim the push tube 7.

[0078] (8) Pull the flexible line 81, the capture member 54 is attached to the proximal surface of the primary septum, and the proximal end of the flexible line 81 is continuously pulled, the secondary septum and the primary septum are attached, and the channel between the two is closed. Figure 12 shown. Example 2

[0079] The second embodiment is substantially the same as the first embodiment, except that the capture member 54 and the compliant support member 52 are fixedly connected.

[0080] In this embodiment, a closing device with a fitting capture device 5 is introduced, which is used to close the channel between the first tissue and the second tissue, including a loading tube 3, a puncture assembly 4 and a fitting capture device 5, wherein the fitting capture device 5 includes a controllable guide 51, a compliant support 52, a connecting member 53 and a capturing member 54, wherein the controllable guide 51 is connected to the distal end of the loading tube 3, and the controllable guide 51 is used to fit the first tissue 1; and the compliant support 52 fits the second tissue 2 and deforms to conform to the shape of the second tissue 2, and when the puncture assembly 4 punctures the second tissue 2, the puncture assembly 4 passes through the capturing member 54 connected to the compliant support 52, as shown in FIG. Figure 13 and Figure 16 shown.

[0081] In the second embodiment, the capture member 54 is fixedly connected to the compliant support member 52, and the operation of the conforming capture device 5 drives the capture member 54 and the closing member 8 to move toward the proximal end; the portion of the closing member 8 that passes through the second tissue 2 and the portion of the closing member 8 that does not pass through the first tissue 1 form a connection inside the body or outside the body, and the closing member 8 forms a closed loop after passing through the first tissue 1 and the second tissue 2. Figure 17 and Figure 18 shown.

[0082] In the second embodiment, the capture member 54 is a grid bracket.

[0083] In the second embodiment, the compliant support member 52 further includes an adjusting portion 5214, the adjusting portion 5214 is connected to the retaining portion 5213, and the adjusting portion 5214 is sleeved outside the pushing tube 7, as shown in FIG. Figure 13 shown.

[0084] In the second embodiment, when the fitting capture device 5 is pre-assembled, the arc portion 5211, the support portion 5212 and the retaining portion 5213 are arranged from the distal end to the proximal end. Figure 15 shown.

[0085] In the second embodiment, the position of the adjusting portion 5214 relative to the pushing tube 7 is changed to change the shape of the compliant support member 52, such as Figure 14 As shown, the moving distance of the second tissue 2 driven by the compliant support member 52 is changed.

[0086] In this regard, the relevant structure and concept of the second embodiment are similar to those of the first embodiment, and thus will not be described again here. Example 3

[0087] The third embodiment is substantially the same as the second embodiment, except that the compliant support member and the connecting member are in a detachable connection relationship.

[0088] In this embodiment, a closing device with a fitting capture device 5 is introduced, which is used to close the channel between a first tissue and a second tissue, including a loading tube 3, a puncture assembly 4 and a fitting capture device 5, wherein the fitting capture device 5 includes a controllable guide 51, a compliant support 52, a connecting member 53 and a capturing member 54, wherein the controllable guide 51 is connected to the distal end of the loading tube 3, and the controllable guide 51 is used to fit the first tissue 1; and the compliant support 52 fits the second tissue 2 and deforms to conform to the shape of the second tissue 2, and when the puncture assembly 4 punctures the second tissue 2, the puncture assembly 4 passes through the capturing member 54 connected to the compliant support 52.

[0089] In the third embodiment, the arc portion 5211 is provided in the middle region or the proximal region of the connecting member 53, and the supporting portion 5212 is in the shape of an arc or a straight rod. Figure 19 shown.

[0090] In the third embodiment, the arc portion 5211 and the connecting member 53 are in a detachable connection relationship, and the connecting member 53 and the pushing tube 7 are in a fixed connection relationship.

[0091] In the third embodiment, the arc portion 5211 includes a connecting hole 5215, the connecting member 53 includes a matching groove 531, a separating wire 71 is provided in the pushing tube 7, the connecting hole 5215 passes through the matching groove 531, the separating wire 71 passes through the connecting hole 5215, and the arc portion 5211 is connected to the connecting member 53; and, the separating wire 71 is recovered, and the arc portion 5211 is separated from the connecting member 53, as shown in FIG. Figure 20 and Figure 21 shown.

[0092] In the third embodiment, the leading member 6 includes a transition structure 61, which is in the shape of a rugby ball or a cone, and is planar or three-dimensional; and when the transition structure reaches the lower edge of the secondary septum, the controllable guide member 51 is released to open, as shown in FIG. Figure 22 shown.

[0093] In this regard, the relevant structure and concept of the third embodiment are similar to those of the second embodiment, and thus will not be described again here.

[0094] The foregoing description of several embodiments of the present application has been presented for illustrative purposes. It is not intended to be exhaustive or to limit the present application to the precise configurations, configurations, and / or steps disclosed, and it is apparent that many modifications and variations are possible in light of the above teachings. It is intended that the scope of the invention and all equivalents thereof be defined by the appended claims.

Claims

1. A closing device with a conformable capture device for closing a passage between a first tissue and a second tissue, characterized in that: It includes a loading tube, a puncture assembly and a fitting capture device, the fitting capture device includes a controllable guide, a compliant support, a connecting member and a capturing member, the controllable guide is connected to the distal end of the loading tube, the controllable guide is used to fit the first tissue; and the compliant support is fitted with the second tissue and deformed to conform to the shape of the second tissue, when the puncture assembly punctures the second tissue, the puncture assembly passes through the capturing member connected to the compliant support.

2. The closing device with a fitting capture device according to claim 1, characterized in that: A closing member is pre-installed in the puncture assembly, and the closing member passes through the first tissue and the second tissue; and the closing member is connected to the capturing member after the puncture assembly passes through the second tissue.

3. The closing device with a fitting capture device according to claim 1 or 2, characterized in that: The capture member is detachably connected to the compliant support member, and the capture member is retained in the target position together with the closing member; The capturing member is in contact with the proximal surface of the second tissue.

4. The closing device with a fitting capture device according to claim 1 or 2, characterized in that: The capturing member is fixedly connected to the compliant support member, and operation of the fitting capturing device drives the capturing member and the closing member to move proximally; the portion of the closing member that passes through the second tissue and the portion of the closing member that does not pass through the first tissue form a connection inside or outside the body, and the closing member forms a closed loop after passing through the first tissue and the second tissue.

5. The closing device with a fitting capture device according to claim 1, characterized in that: The connecting member is connected to the controllable guide member and the compliant support member, and the free end of the controllable guide member is facing the distal direction, and the free end of the compliant support member is facing the proximal direction. When the compliant support member is in contact with the second tissue, it provides supporting force for the puncture assembly; and the controllable guide member and the compliant support member are arranged opposite to each other on the circumference.

6. The closure device with a fit capture device according to claim 1, wherein: When the compliant support member is in contact with the second tissue, its shape is adapted to the second tissue. The compliant support member includes a plurality of support rods, and the plurality of support rods form a three-dimensional support surface. Moreover, when the compliant support member is in contact with the second tissue, different support rods are deformed to different degrees.

7. The closing device with a fitting capture device according to claim 6, characterized in that: The support rod includes an arc portion, a supporting portion and a retaining portion; and the arc portion is connected to the connecting piece, the supporting portion provides a supporting area for the second tissue, and the retaining portion is located in the proximal direction of the connecting piece in a natural state.

8. The closing device with a fitting capture device according to claim 7, characterized in that: It also includes a pushing tube and a leading component, the fitting capture device is connected to the pushing tube, and the pushing tube is sleeved in the leading component; the leading component and the controllable guide member; and the compliant support member also includes an adjustment part, the adjustment part is connected to the retaining part, and the adjustment part is sleeved outside the pushing tube.

9. The closing device with a fitting capture device according to claim 8, characterized in that: The position of the adjusting portion relative to the pushing tube is changed to change the shape of the compliant support member, thereby changing the moving distance of the second tissue driven by the compliant support member.

10. The closure device with a fit capture device according to claim 1, wherein: The connecting member is detachably connected to the compliant support member; or, the connecting member is detachably connected to the controllable guide member; or, the connecting member includes a first connecting body and a second connecting body, the first connecting body and the second connecting body are detachably connected, and the two are respectively connected to the controllable guide member and the compliant support member.

11. The closing device with a fitting capture device according to claim 8, characterized in that: The leading member includes a transition structure, which is in the shape of a rugby ball or a cone, and is planar or three-dimensional; and when the transition structure reaches the lower edge of the first tissue, the controllable guide is released to open.

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