Compound plant extract composition and preparation method thereof

Abstract

The invention relates to the technical field of plant extraction, and particularly discloses a compound plant extraction composition and a preparation method thereof. The compound plant extract composition is prepared from the following raw materials in parts by weight: 8-12 parts of schefflera arboricola flowers, 10-16 parts of a blood-activating synergistic complex, 10-16 parts of a stability-maintaining balance complex and 2-4 parts of radix angelicae. The blood-activating synergistic complex is composed of Chinese angelica and peach kernel; the stability-maintaining balance complex is prepared from radix polygonati officinalis and radix ampelopsis; the preparation method comprises the following steps: crushing and mixing the schefflera chamaecyparis flowers, the blood-activating synergistic complex, the stability-maintaining balance complex and the radix angelicae, performing reflux extraction by using an ethanol solution, and concentrating the obtained extracting solution to obtain the compound plant extraction composition. The compound plant extract composition disclosed by the invention can realize excellent and remarkable exertion of triple effects of activating blood, resisting wrinkles and tightening, moisturizing and repairing, and resisting inflammation and maintaining stability, and finally, the overall application effect is remarkably enhanced.

Description

Technical Field

[0001] The present application relates to the field of plant extraction technology, and more specifically, to a compound plant extract composition and a preparation method thereof. Background Art

[0002] Plant extracts are made from plants and use physical and chemical methods to obtain one or more active ingredients without changing their original structure. They are widely used in medicine, food, daily chemicals and other fields. Commonly used extraction methods include solvent extraction, ultrasonic / microwave extraction and enzymatic hydrolysis.

[0003] The scientific name of the soap tree is Acacia, which belongs to the genus Acacia in the Fabaceae family. The flowers of the soap tree are bright golden yellow, and the petals are connected into a tube shape. When in full bloom, the tree is full of golden color and has a strong sweet fragrance. The main active ingredients are volatile aromatic oils, flavonoids and quercetin. Therefore, solvent extraction or distillation methods are often used to extract and process the soap tree flowers. The obtained soap tree flower extract can be used in cosmetics. Among them, the volatile aromatic oils in the soap tree flower extract can give the extract a special aromatic smell and antibacterial properties, while the flavonoids can promote collagen synthesis and quercetin can reduce the secretion of inflammatory factors. The combination of the two can provide anti-wrinkle, firming and anti-inflammatory effects on the skin and enhance the skin barrier function.

[0004] In traditional medicine, the flower of the soap tree has astringent and hemostatic properties. If used alone on the skin, it may over-tighten the pores, aggravate skin dryness, and make it difficult to effectively play the anti-wrinkle, firming, anti-inflammatory and stabilizing role. Therefore, it is used in combination with other plants for extraction. It can not only effectively reduce the above-mentioned adverse effects, but also achieve the complementary and synergistic effect of active ingredients, and realize the triple effect of "blood circulation, anti-wrinkle and firming - moisturizing and repairing - anti-inflammatory and stabilizing", bringing a significant enhancement to the overall application effect. Summary of the Invention

[0005] In order to achieve the excellent triple effects of "blood circulation, anti-wrinkle and firming - moisturizing and repairing - anti-inflammatory and stabilizing" after the mixed extraction of the flowers of the Quillaja sapodilla tree and other plants, the present application provides a compound plant extract composition and a preparation method thereof.

[0006] In a first aspect, the present application provides a compound plant extract composition, which adopts the following technical solution: A compound plant extract composition is prepared from the following raw materials in parts by weight: 8-12 parts of Sophora japonica flowers; 10-16 parts of blood-activating and synergistic compound; 10-16 parts of stabilizing balance complex; 2-4 parts Angelica dahurica; The blood-activating and synergistic compound is composed of angelica and peach kernel; The stabilizing balance complex consists of polygonatum and white ampelopsis.

[0007] By employing this technical solution, the ferulic acid and ligustilide in angelica sinensis promote local blood perfusion and accelerate the removal of metabolic waste. Amygdalin and triolein in peach kernel activate the plasminogen system and inhibit excessive platelet aggregation. Their combination increases blood circulation efficiency by 40%, promoting deeper skin delivery and absorption. Polysaccharides in polygonatum odoratum hydrogen-bond to stratum corneum lipids, reducing transepidermal water loss and forming a hyaluronic acid-like moisturizing film, enhancing moisture retention. Gallic acid and tannins in ampelopsis pilosula promote desmosomal protein synthesis in keratinocytes, repairing barrier integrity, blocking the NF-κB signaling pathway, inhibiting the release of pro-inflammatory cytokines such as TNF-α and IL-6, and effectively mitigating dryness. The combination of these two ingredients delivers excellent moisturizing and repairing benefits, complementing the sycamore flower to achieve a stabilizing balance. Imperatorin in angelica dahurica enhances stratum corneum permeability, allowing active ingredients to accumulate in the basal layer of the epidermis. On the basis of using the flowers of the soap tree, through the blood-activating and synergistic complex composed of angelica and peach kernel, the stabilizing and balancing complex composed of polygonatum and white peony root, and the cooperation between angelica dahurica, the efficacy of the flowers of the soap tree can be fully exerted, effectively forming a complementary and synergistic effect, and achieving the excellent and significant performance of the triple effects of "blood-activating, anti-wrinkle and firming - moisturizing and repairing - anti-inflammatory and stabilizing", ultimately bringing about a significant enhancement of the overall application effect.

[0008] Preferably, the blood-activating and synergistic compound is composed of the following raw materials in parts by weight: 5-8 parts of angelica; 5-8 servings of peach kernels.

[0009] By adopting the above technical solution, when angelica and peach kernel in the above dosage range are used in combination, the effective ingredients obtained by extraction can significantly enhance the permeability of skin capillaries, amplify the capillary blood flow rate, accelerate deep skin delivery and absorption, achieve dual-effect blood circulation to drive collagen regeneration, and thus bring better corresponding effects.

[0010] Preferably, the weight ratio of the angelica sinensis to the peach kernel is 1:1.

[0011] By adopting the above technical solution, when the angelica and peach kernel in the above weight ratio are used for extraction, the active ingredients can form an excellent and stable combination with the active ingredients of other raw materials, which is conducive to obtaining a compound plant extract composition with better application quality.

[0012] Preferably, the stabilizing balance complex is composed of the following raw materials in parts by weight: 6-10 parts of Polygonatum odoratum; 4-6 parts of white ampelopsis.

[0013] By adopting the above technical solution, when the above-mentioned dosage range of Polygonatum odoratum and Smilax glabra are used in combination, the effective ingredients obtained by extraction can form a hyaluronic acid-like moisturizing film, significantly increase the water content of the stratum corneum, create a microenvironment for maintaining stability and balance, and bring excellent enhanced barrier repair effect, and the overall effective ingredients have a stable combination and coordination effect with the effective ingredients of the Quillaja sapodilla flower, thereby bringing better corresponding effects.

[0014] Preferably, the weight ratio of the polygonatum and the white ampelopsis is 8:5.

[0015] By adopting the above technical solution, when the above weight ratio of Polygonatum odoratum and Bletilla striata is used for extraction, the active ingredients can form an excellent and stable combination with the active ingredients of other raw materials, which is conducive to obtaining a compound plant extract composition with better application quality.

[0016] In a second aspect, the present application provides a method for preparing a compound plant extract composition, which adopts the following technical solution: A method for preparing a compound plant extract composition comprises the following steps: (1) preparing raw materials including salvia officinalis flower, blood-activating and synergistic compound, stabilizing and balancing compound, and Angelica dahurica according to a proportion; (2) The flowers of the sycamore tree, the blood-activating and synergistic complex, the stabilizing and balancing complex and Angelica dahurica in step (1) are crushed and mixed, and then refluxed and extracted with an ethanol solution. The obtained extract is concentrated to obtain a compound plant extract composition.

[0017] By adopting the above technical solution, the above operation is simple and is suitable for large-scale industrial production as a whole; and the ethanol reflux method can simultaneously extract fat-soluble and water-soluble components, avoiding the activity loss caused by step-by-step extraction, and ensuring that the final quality of the compound plant extract composition is excellent; at the same time, after the raw materials are mixed, they are extracted by a one-pot method, which also has a higher overall production efficiency.

[0018] Preferably, step (2) is specifically configured as follows: after the flowers of the sycamore tree, the blood-activating and synergistic complex, the stabilizing and balancing complex and the angelica dahurica in step (1) are crushed and mixed, a complex enzyme consisting of cellulase and pectinase is added for enzymatic hydrolysis, and then the enzyme is inactivated, and then reflux extraction is performed with an ethanol solution, and the obtained extract is concentrated to obtain a compound plant extract composition.

[0019] By adopting the above technical solution, enzymatic hydrolysis treatment can assist in breaking the wall, accelerate the full dissolution of effective substance components, and thus improve the extraction effect; and after the enzymatic hydrolysis treatment is completed, enzyme inactivation treatment can immediately terminate the enzyme activity, avoiding the presence of residual enzymes that cause abnormal ethanol extraction reactions; therefore, through the application and coordination of the above operations, the content of effective ingredients in the compound plant extract composition and the mutual combination and coordination forms can be significantly improved, and the corresponding effects brought about after application are also significantly improved.

[0020] Preferably, in step (2), the weight ratio of the added complex enzyme is 0.4-0.5%, and the weight ratio of cellulase to pectinase is 1:(1.8-2.4).

[0021] By adopting the above technical solution, cellulase can decompose the primary wall cellulose skeleton, destroy the rigid structure of the cell wall, and increase the porosity; pectinase can preferentially decompose the pectin in the intercellular layer, release the adhesion between cells, and release the embedded active ingredients; and when cellulase and pectinase are combined into a composite enzyme according to the above ratio and added for application, efficient and low-loss extraction can be achieved through "pectinase-led softening-cellulase-assisted mesh breaking", thereby exerting an excellent enzymatic hydrolysis effect, ensuring that the final compound plant extract composition has better application quality.

[0022] Preferably, in step (2), the specific operation of reflux extraction with ethanol solution is: first reflux extraction with 75-85% ethanol at 55-65°C for 1-1.5h, and then reflux extraction with 45-55% ethanol at 40-50°C for 1-1.5h.

[0023] By adopting the above technical solution, the high alcohol in the first stage preferentially dissolves the medium polarity components, while the low alcohol in the second stage specifically extracts the high polarity components. Through the "polarity-temperature dual-step regulation", the dissolution of impurities can be reduced, and the extraction time can be effectively shortened and the activity and yield of the effective substance components can be improved, thereby obtaining a compound plant extract composition with better application quality.

[0024] Preferably, in step (1), the angelica and polygonatum are crushed to 60-80 mesh, the sycamore flower and white ampelopsis are crushed to 100-120 mesh, and the peach kernel and angelica dahurica are crushed to 30-50 mesh.

[0025] By adopting the above technical solution, angelica and polygonatum contain polysaccharides and cellulose, which are crushed to 60-80 mesh to increase the dissolution area; Quillaja sapodilla flower and Bletilla striata contain cuticle structure and need to be ultrafinely crushed to 100-120 mesh to destroy the cell wall; peach kernel and Angelica dahurica contain volatile oil, which are maintained at 30-50 mesh to avoid high-temperature volatilization loss; through graded crushing, the extraction efficiency and component protection are balanced, and adverse reactions in the extraction process are suppressed, so that the raw materials after mixing have excellent extraction effect in the one-pot extraction, thereby ensuring that the obtained compound plant extract composition has stable and better quality.

[0026] In summary, this application has the following beneficial effects: 1. This application, through the combination of the blood-activating and synergistic complex composed of angelica and peach kernel, the stabilizing and balancing complex composed of polygonatum and white ampelopsis, and the combination of angelica, can fully exert the efficacy of the flowers of the sycamore tree, effectively form complementary synergy, and achieve the excellent and significant triple effects of "blood-activating, anti-wrinkle, firming, moisturizing, repairing, and anti-inflammatory and stabilizing", ultimately bringing about a significant enhancement of the overall application effect; 2. This application utilizes graded crushing to balance extraction efficiency and ingredient protection, and adopts enzymatic treatment through "pectinase-led softening-cellulase-assisted mesh breaking" to achieve efficient and low-loss extraction, and through "polarity-temperature dual-step regulation", it can reduce impurity dissolution, effectively shorten the extraction time and improve the activity and yield of effective substance components, thereby ensuring that the final compound plant extract composition has better application quality. DETAILED DESCRIPTION

[0027] The present application is further described in detail below with reference to the following examples and comparative examples.

[0028] Unless otherwise specified, the raw materials used in the examples and comparative examples of the present application are all commercially available.

[0029] Sophora flavescens flower, Angelica dahurica, Angelica sinensis, Peach kernel, Polygonatum odoratum, and Bletilla striata were purchased from Bozhou Renyi Chinese Medicinal Materials Sales Co., Ltd. Cellulase and pectinase were purchased from Shanghai ELISA Biotechnology Co., Ltd. Example

[0030] Example 1 A compound plant extract composition, the raw materials used in its preparation and their corresponding weight parts are shown in Table 1, and it is prepared by the following steps: (1) preparing raw materials including salvia officinalis flower, blood-activating and synergistic compound, stabilizing and balancing compound, and Angelica dahurica according to a proportion; (2) The flowers of the sycamore tree, the blood-activating and synergistic complex, the stabilizing and balancing complex and the angelica dahurica in step (1) are crushed into 50 mesh and mixed, and then refluxed and extracted twice with a 65% ethanol solution at 60° C. for 1.5 hours each time. The obtained extracts are combined and concentrated to an extract with a relative density of 1.15 to obtain a compound plant extract composition.

[0031] Note: In the above operation, the blood-activating and synergistic compound is composed of Angelica sinensis and Peach Kernel, and their corresponding weight parts are shown in Table 2; the stabilizing and balancing compound is composed of Polygonatum odoratum and Bletilla striata, and their corresponding weight parts are shown in Table 3.

[0032] Example 2-3 A compound plant extract composition, which is different from Example 1 in that the raw materials used in its preparation and their corresponding weight parts are shown in Table 1.

[0033] Table 1 Raw materials used in the preparation of Examples 1-3 and their corresponding weight parts (parts / kg) raw material Example 1 Example 2 Example 3 Soap Tree Flowers 10 8 12 Blood-activating and synergistic complex 13 10 16 Stable balance complex 13 10 16 Angelica dahurica 3 2 4 Examples 4-5 A compound plant extract composition, which is different from Example 1 in that the blood-activating and synergistic compound is composed of angelica and peach kernel, and their corresponding weight parts are shown in Table 2.

[0034] Table 2 Raw materials of the blood-activating and synergistic complexes of Examples 1, 4-5 and their corresponding weight portions (parts / kg) raw material Example 1 Example 4 Example 5 Angelica 6.5 5 8 peach kernel 6.5 8 5 Examples 6-7 A compound plant extract composition, which is different from Example 1 in that the stabilizing and balancing complex is composed of Polygonatum odoratum and Bletilla striata, and their corresponding weight parts are shown in Table 3.

[0035] Table 3 Raw materials of the stable equilibrium complexes of Examples 1, 6-7 and their corresponding weight parts (parts / kg) raw material Example 1 Example 6 Example 7 Polygonatum odoratum 8 6 10 White mulberry 5 6 4 Example 8 A compound plant extract composition, which differs from Example 1 in that step (2) is specifically configured as follows: after the flowers of the sycamore tree, the blood-activating and synergistic complex, the stabilizing and balancing complex and Angelica dahurica in step (1) are crushed and mixed, a complex enzyme consisting of cellulase and pectinase is added to perform enzymatic hydrolysis at 65°C for 50 minutes, and then an enzyme inactivation treatment is performed at 95°C for 10 minutes, followed by reflux extraction with an ethanol solution, and the obtained extract is concentrated to obtain the compound plant extract composition.

[0036] Note: In the above operation, the weight ratio of the added complex enzyme is 0.45%, and the weight ratio of cellulase to pectinase is 1:2.1.

[0037] Example 9 A compound plant extract composition is different from Example 8 in that the weight proportion of the added complex enzyme is 0.4%, and the weight ratio of cellulase to pectinase is 1:1.8.

[0038] Example 10 A compound plant extract composition is different from Example 8 in that the weight proportion of the added complex enzyme is 0.5%, and the weight ratio of cellulase to pectinase is 1:2.4.

[0039] Example 11 A compound plant extract composition, which is different from Example 8 in that no cellulase is used in the enzymatic hydrolysis treatment.

[0040] Example 12 A compound plant extract composition, which is different from Example 8 in that pectinase is not used in the enzymatic hydrolysis treatment.

[0041] Example 13 A compound plant extract composition, which differs from Example 1 in that, in step (2), the specific operation of reflux extraction with ethanol solution is: first reflux extraction with 80% ethanol at 60°C for 1.25h, and then reflux extraction with 50% ethanol at 45°C for 1.25h.

[0042] Example 14 A compound plant extract composition, which differs from Example 1 in that, in step (2), the specific operation of reflux extraction with ethanol solution is: first reflux extraction with 75% ethanol at 55°C for 1.5 hours, and then reflux extraction with 45% ethanol at 40°C for 1.5 hours.

[0043] Example 15 A compound plant extract composition is different from Example 1 in that, in step (2), the specific operation of reflux extraction with ethanol solution is: first reflux extraction with 85% ethanol at 65°C for 1 hour, and then reflux extraction with 55% ethanol at 50°C for 1 hour.

[0044] Example 16 A compound plant extract composition is different from Example 1 in that, in step (1), angelica sinensis and polygonatum odoratum are crushed to 70 mesh, sylvestris chinensis flower and white ampelopsis are crushed to 110 mesh, and peach kernel and angelica dahurica are crushed to 40 mesh.

[0045] Example 17 A compound plant extract composition is different from Example 1 in that, in step (1), angelica sinensis and polygonatum odoratum are crushed to 60 mesh, sylvestris chinensis flower and white ampelopsis are crushed to 100 mesh, and peach kernel and angelica dahurica are crushed to 30 mesh.

[0046] Example 18 A compound plant extract composition is different from Example 1 in that, in step (1), angelica sinensis and polygonatum odoratum are crushed to 80 mesh, sylvestris chinensis flower and white ampelopsis are crushed to 120 mesh, and peach kernel and angelica dahurica are crushed to 50 mesh.

[0047] Comparative Example Comparative Example 1 A compound plant extract composition is different from Example 1 in that no blood-activating and synergistic complex or stabilizing and balancing complex is used in the preparation raw materials.

[0048] Comparative Example 2 A compound plant extract composition is different from Example 1 in that the blood-activating and synergistic compound and Angelica dahurica are not used in the preparation raw materials.

[0049] Comparative Example 3 A compound plant extract composition is different from Example 1 in that no stabilizing balance complex and Angelica dahurica are used in the preparation of the composition.

[0050] Comparative Example 4 A compound plant extract composition is different from Example 1 in that no blood-activating and synergistic compound is used in the preparation raw materials.

[0051] Comparative Example 5 A compound plant extract composition is different from Example 1 in that no stabilizing equilibrium complex is used in the preparation raw materials.

[0052] Comparative Example 6 A compound plant extract composition is different from Example 1 in that Angelica dahurica is not used in the preparation raw materials.

[0053] Comparative Example 7 A compound plant extract composition is different from Example 1 in that the blood-activating and synergistic complex, the stabilizing and balancing complex and Angelica dahurica are not used in the preparation raw materials.

[0054] Performance test samples: The compound plant extract compositions obtained in Examples 1-18 were selected as test samples 1-18, and the compound plant extract compositions obtained in Comparative Examples 1-7 were selected as control samples 1-7.

[0055] Test Method: The test environment was maintained at a constant temperature of 20°C and a relative humidity of 50%. Fifty healthy subjects aged 35-55 were randomly divided into 25 groups, with an equal number of men and women. With informed consent, the subjects were asked to perform a simple cleansing before the test, which took place at 9:00 AM and 9:00 PM. The test procedure involved weighing 0.5 ml of the compound plant extract composition onto a 2cm*2cm non-woven membrane, soaking it in water, and applying it to the subject's cheek for 15 minutes. The membrane was then removed and allowed to rest for 10 minutes.

[0056] (1) Wrinkle volume improvement test: Use Three-dimensional imaging technology was used to verify the wrinkle volume reduction rate after 8 weeks, and the average value of the two people tested in each group was taken; (2) Transepidermal water loss change test: The test was performed using the Tewameter™ 300 probe of the German CK skin tester. Transepidermal water loss change = (water loss after one week of use by the subject - initial water loss before use by the subject) / initial water loss before use by the subject. The average value of the two tests in each group was taken. (3) Human erythema index reduction rate: 10% lactic acid solution was used to stimulate the cheek skin (test area) of the subject to produce erythema reaction. The erythema index was tested by MX18, and then the compound plant extract combination was used for 1 week and then tested in the same way. The erythema index reduction rate of the human body = (erythema index before use of the subject - erythema index after 1 week of use of the subject) / erythema index before use of the subject, and the average value of the two tests in each group was taken.

[0057] Table 4 Test results of test samples 1-18 and control samples 1-7 Combining Examples 1-3 and Comparative Examples 1-7 with Table 4, it can be seen that the blood-activating and synergistic complex composed of Angelica sinensis and peach kernel, the stabilizing and balancing complex composed of Polygonatum odoratum and Bletilla striata, and the combination of Angelica dahurica can achieve the excellent and significant triple effects of "activating blood circulation, anti-wrinkle, firming, moisturizing and repairing, and anti-inflammatory and stabilizing". The wrinkle volume reduction rate, transepidermal water loss change value, and erythema index decrease rate obtained by the above tests are significantly better; however, if any one or two of the blood-activating and synergistic complex, the stabilizing and balancing complex, and Angelica dahurica are mixed and extracted with the flowers of the Sophora japonica, it is found that the compound plant extract composition has limited effect on the improvement of the wrinkle volume reduction rate, the transepidermal water loss change value, and the erythema index decrease rate, and the effects of each other are simply superimposed. Only when the three are used in combination can the overall effect of the compound plant extract composition be significantly enhanced.

[0058] Combining Example 1 and Examples 8-12 with Table 4, it can be seen that enzymatic hydrolysis can assist in breaking the cell wall and accelerate the full dissolution of the effective substance components, thereby improving the extraction effect, and significantly improving the corresponding effects brought about by the application of the compound plant extract composition. The above tests show that the wrinkle volume reduction rate, the change in transepidermal water loss, and the erythema index decrease rate are all significantly improved; and for the use of composite enzymes, if only cellulase or pectinase is used, the corresponding effects brought about by the combined application of the two enzymes are far inferior.

[0059] Combining Example 1 and Examples 13-15 with Table 4, it can be seen that in the ethanol solution reflux extraction operation, 75-85% ethanol is first refluxed at 55-65° C. for 1-1.5 h, and then 45-55% ethanol is refluxed at 40-50° C. for 1-1.5 h. This "polarity-temperature dual-step control" can reduce impurity dissolution, effectively shorten the extraction time, and increase the activity and yield of the effective substance components, thereby improving the overall application effect of the compound plant extract composition.

[0060] From Example 1 and Examples 16-18 and Table 4, it can be seen that angelica and polygonatum are crushed to 60-80 mesh, salsa versicolor flower and white ampelopsis are crushed to 100-120 mesh, and peach kernel and angelica dahurica are crushed to 30-50 mesh. The extraction efficiency and component protection can be balanced by graded crushing, and adverse reactions during the extraction process can be suppressed, so that the raw materials can be mixed and have an excellent extraction effect in the one-pot extraction, thereby ensuring that the obtained compound plant extract composition has stable and better quality.

[0061] This specific embodiment is merely an explanation of the present application and is not a limitation of the present application. After reading this specification, those skilled in the art may make non-creative modifications to the present embodiment as needed, but as long as they are within the scope of the claims of the present application, they are protected by the patent law.

Claims

1. A compound plant extract composition, characterized in that: Made from the following raw materials in parts by weight: 8-12 parts of Sophora japonica flowers; 10-16 parts of blood-activating and synergistic compound; 10-16 parts of stabilizing balance complex; 2-4 parts Angelica dahurica; The blood-activating and synergistic compound is composed of angelica and peach kernel; The stabilizing balance complex consists of polygonatum and white ampelopsis.

2. The compound plant extract composition according to claim 1, characterized in that: The blood-activating and synergistic compound is composed of the following raw materials in parts by weight: 5-8 parts of angelica; 5-8 servings of peach kernels.

3. The compound plant extract composition according to claim 2, characterized in that: The weight ratio of the angelica sinensis to the peach kernel is 1:

1.

4. The compound plant extract composition according to claim 1, characterized in that: The stabilizing and balancing complex is composed of the following raw materials in parts by weight: 6-10 parts of Polygonatum odoratum; 4-6 parts of white ampelopsis.

5. The compound plant extract composition according to claim 4, characterized in that: The weight ratio of the polygonatum and white ampelopsis is 8:

5.

6. The method for preparing the compound plant extract composition according to claim 1, wherein: The following steps are involved: (1) Prepare raw materials including salvia officinalis flower, blood-activating and synergistic compound, stabilizing and balancing compound, and Angelica dahurica according to the proportions; (2) The flowers of the sycamore tree, the blood-activating and synergistic complex, the stabilizing and balancing complex and Angelica dahurica in step (1) are crushed and mixed, and then refluxed and extracted with an ethanol solution. The obtained extract is concentrated to obtain a compound plant extract composition.

7. The method for preparing the compound plant extract composition according to claim 6, wherein: Step (2) is specifically configured as follows: after the flowers of the sycamore tree, the blood-activating and synergistic complex, the stabilizing and balancing complex and Angelica dahurica in step (1) are crushed and mixed, a composite enzyme consisting of cellulase and pectinase is added for enzymatic hydrolysis, and then the enzyme is inactivated, and then the mixture is extracted by refluxing with an ethanol solution, and the obtained extract is concentrated to obtain a compound plant extract composition.

8. The method for preparing the compound plant extract composition according to claim 7, wherein: In step (2), the weight ratio of the added complex enzyme is 0.4-0.5%, and the weight ratio of cellulase to pectinase is 1:(1.8-2.4).

9. The method for preparing the compound plant extract composition according to claim 6, wherein: In step (2), the specific operation of reflux extraction with ethanol solution is: first, reflux extraction with 75-85% ethanol at 55-65°C for 1-1.5h, and then reflux extraction with 45-55% ethanol at 40-50°C for 1-1.5h.

10. The method for preparing the compound plant extract composition according to claim 6, wherein: In step (1), the angelica and polygonatum are crushed to 60-80 mesh, the flowers of the sycamore tree and the white ampelopsis are crushed to 100-120 mesh, and the peach kernel and the angelica dahurica are crushed to 30-50 mesh.

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