Danshen heart-protecting tea atomized liquid adaptive to atomization equipment and preparation method thereof

Abstract

The invention discloses a Danshen heart-protecting tea atomized liquid matched with atomization equipment and a preparation method thereof. The atomized liquid is prepared from such natural components as salvia miltiorrhiza, green tea, eucommia ulmoides, apocynum venetum, sophora flower, polygonum multiflorum, loranthus parasiticus, black sesame, lily, chrysanthemum, corn stigma and schisandra chinensis as raw materials, and a core efficacy system of the atomized liquid is as follows: such components as salvia miltiorrhiza and eucommia ulmoides synergistically act on a cardiovascular system, such components as green tea and chrysanthemum assist in promoting microcirculation, such components as black sesame and corn stigma synergistically regulate lipid metabolism, and promote blood circulation. Green tea polyphenol, schisandra chinensis and the like form an anti-oxidation synergistic system, lily, apocynum venetum and other components synergistically relieve the nervous system, efficient delivery of active ingredients in the lung is achieved through an atomization device, and compared with a traditional intake mode, the traditional Chinese medicine composition has a higher absorption rate and is especially suitable for groups needing daily health maintenance.

Description

Technical Field

[0001] The present invention relates to the technical field of traditional Chinese medicine tea beverages, and in particular to a danshen heart-protecting tea beverage atomization liquid adapted for atomization equipment and a preparation method thereof. Background Art

[0002] Traditional oral Chinese herbal teas have long been an important way for people to obtain nutrients, but they have many limitations that are difficult to ignore. In terms of absorption efficiency, oral teas must undergo a series of complex digestive organs, and the absorption process of active ingredients is long and tedious. During gastrointestinal digestion, a large number of active ingredients are destroyed by gastric acid, digestive enzymes, etc., and many active ingredients undergo structural changes, losing their original health-promoting activity, greatly reducing the actual efficacy of the tea. In addition, for some special populations, such as the elderly with weak gastrointestinal function and patients with gastrointestinal diseases, oral teas may cause discomfort or even aggravate their condition. At the same time, the irritation of the tea may also lead to symptoms such as bloating and stomach pain.

[0003] With the continuous advancement of modern medical technology, nebulization technology has gradually demonstrated its unique advantages. Nebulization converts drugs or nutrients into tiny particles that can directly and rapidly reach the respiratory tract and even the lungs. Compared to traditional oral administration, their absorption rate is significantly improved. Studies have shown that nebulization can increase drug or nutrient absorption several times, improving bioavailability by 30%-50%. Furthermore, nebulization requires a relatively small dosage, which, while achieving the same therapeutic or health-promoting effect, can reduce the metabolic burden on vital organs like the liver and kidneys, minimizing the risk of potential side effects. Developing tea into a nebulized liquid represents an innovative breakthrough in traditional tea beverages. On the one hand, it leverages the technological advantages of nebulization, enabling faster and more efficient absorption of the active ingredients in tea, significantly enhancing its health benefits. On the other hand, nebulized tea liquid offers a new alternative for those who cannot effectively absorb the nutrients of tea through traditional oral administration, such as those with dysphagia or gastrointestinal problems, broadening the scope of tea's applicability. However, there is currently a lack of tea beverages on the market that use salvia miltiorrhiza and green tea as core ingredients and are specifically designed for aerosol inhalation. Therefore, developing such products has great potential and broad market prospects in our fast-paced modern lives, as they can meet consumers' growing demand for efficient and convenient healthcare options. Summary of the Invention

[0004] The purpose of the present invention is to provide a Danshen Heart Protecting Tea atomized liquid suitable for atomization equipment and a preparation method thereof, which uses Danshen and green tea as core raw materials, and is combined with various other Chinese medicinal materials that lower blood lipids and blood pressure, regulate metabolism, protect cardiovascular system, resist oxidation and fatigue, and improve the body's immunity. It combines the characteristics of green tea and fully utilizes the technical advantages of atomization inhalation, so that the effective ingredients in the tea can be absorbed by the human body more quickly and efficiently, and is particularly suitable for groups that need daily health care.

[0005] To achieve the above object, the present invention provides the following technical solutions:

[0006] On the one hand, the present invention provides a Danshen heart-protecting tea formula that is compatible with atomization equipment, and the tea formula is composed of the following ingredients: Danshen, green tea, Eucommia ulmoides, Apocynum venetum, Sophora japonica flower, Polygonum multiflorum, Viscum album, black sesame, lily, chrysanthemum, corn silk, and Schisandra chinensis.

[0007] Furthermore, the above-mentioned tea beverage formula contains the following weight ratios: 10-20g of Salvia miltiorrhiza, 5-10g of green tea, 5-10g of Eucommia ulmoides, 3-8g of Apocynum venetum, 5-8g of Sophora japonica flower, 5-10g of Polygonum multiflorum, 5-10g of Viscum album, 8-12g of black sesame, 6-12g of lily, 3-8g of chrysanthemum, 3-8g of corn silk, and 3-8g of Schisandra chinensis.

[0008] Furthermore, the above-mentioned tea beverage formula contains the following weight ratios: 10 or 20g of Salvia miltiorrhiza, 5 or 10g of green tea, 5 or 10g of Eucommia ulmoides, 3 or 8g of Apocynum venetum, 5 or 8g of Sophora japonica flower, 5 or 10g of Polygonum multiflorum, 5 or 10g of Viscum album, 8 or 12g of black sesame, 6 or 12g of lily, 3 or 8g of chrysanthemum, 3 or 8g of corn silk, and 3 or 8g of Schisandra chinensis.

[0009] Furthermore, the above-mentioned tea beverage formula contains the following weight ratios: 15g of Salvia miltiorrhiza, 8g of green tea, 7g of Eucommia ulmoides, 5g of Apocynum venetum, 7g of Sophora japonica flower, 8g of Polygonum multiflorum, 8g of Viscum album, 10g of black sesame, 8g of lily, 5g of chrysanthemum, 5g of corn silk, and 5g of Schisandra chinensis.

[0010] Furthermore, the tea beverage formula has the following pharmacological effects:

[0011] Salvia miltiorrhiza: It is rich in various active ingredients such as tanshinone and salvianolic acid. It has significant effects of promoting blood circulation, removing blood stasis, promoting menstruation and relieving pain. It can dilate coronary arteries, increase coronary blood flow, effectively improve myocardial ischemia and hypoxia, and relieve angina symptoms. It is of great significance in the treatment of coronary heart disease. Among them, tanshinone IIA can inhibit platelet aggregation, reduce blood viscosity, and promote blood circulation. Salvianolic acids have antioxidant and anti-thrombotic effects, which can protect the cardiovascular system.

[0012] Green tea: Green tea is rich in tea polyphenols, caffeine, and theanine. Tea polyphenols are the key active ingredient, possessing powerful antioxidant properties that can scavenge free radicals, slow cell aging, and prevent the onset of various chronic diseases. Caffeine stimulates the central nervous system, refreshing the mind and improving work efficiency and concentration. Theanine can relieve tension, improve sleep quality, and synergize with caffeine to enhance cognitive function. Green tea also boasts antibacterial and anti-inflammatory properties, as well as lipid-lowering and weight-loss benefits, providing numerous benefits for maintaining human health.

[0013] Eucommia ulmoides: Containing ingredients such as eucommia gum, aucubin, pinoresinol diglucoside, and flavonoids (such as quercetin), it has been shown to lower blood pressure, nourish the liver and kidneys, and strengthen bones and muscles. Eucommia gum and aucubin are the main active ingredients, which can dilate blood vessels, reduce peripheral vascular resistance, and thus lower blood pressure, making it suitable for long-term conditioning in patients with hypertension. It can enhance liver and kidney function, improve immunity, and alleviate symptoms such as low back and knee weakness, limb fatigue, and aid recovery in the elderly and those recovering from heart disease.

[0014] Apocynum venetum: Contains flavonoids (quercetin, isoquercetin, etc.), cardiac glycosides (canadenine, etc.), amino acids, organic acids, etc. Flavonoid compounds are the main active ingredients, which have the effects of calming the liver and tranquilizing the mind, clearing away heat and promoting diuresis. It can relieve dizziness, headache, insomnia, irritability and other symptoms caused by blood pressure fluctuations in patients with hypertension, regulate the function of the nervous system, promote urine excretion, reduce edema, and assist in lowering blood pressure. It has a good effect on patients with hypertension and edema.

[0015] Sophora japonica flower: Containing rutin, quercetin, sophora japonica amine, sophora japonica ester, and sophora japonica amine propyl, it has the effects of cooling blood, stopping bleeding, clearing the liver, and purging heat. Rutin, the primary active ingredient, can treat bleeding symptoms such as nosebleeds and gum bleeding caused by excessive blood heat. Rutin strengthens capillary toughness, reduces vascular permeability, and prevents bleeding tendencies. It can also relieve dizziness, red and swollen eyes, and other symptoms caused by liver fire, and help lower blood pressure. It is particularly suitable for patients with hypertension and liver fire.

[0016] Polygonum multiflorum: Contains stilbene glycosides, lecithin, emodin, and chrysophanol. It has antioxidant and lipid-lowering properties. Stilbene glycosides are the key active ingredient, scavenging free radicals, delaying cell aging, and protecting the cardiovascular system from oxidative damage. It also inhibits cholesterol synthesis, promotes lipid metabolism, lowers blood cholesterol and triglyceride levels, prevents atherosclerosis, and safeguards cardiovascular health in the elderly.

[0017] Mistletoe: Contains quercetin, syringin, oleanolic acid, and flavonoids, which improve blood circulation, assist in lowering blood pressure, nourish the liver and kidneys, and strengthen bones and muscles. The main active ingredients, quercetin and flavonoids, dilate blood vessels, increase coronary blood flow, and improve myocardial blood supply, providing an auxiliary therapeutic effect for cardiovascular diseases such as coronary heart disease and angina pectoris. It can regulate vascular tone and lower blood pressure, while also nourishing the liver and kidneys and strengthening bones and muscles, helping hypertensive patients control their condition and promote recovery.

[0018] Black sesame: Rich in unsaturated fatty acids (such as linoleic acid and linolenic acid), protein, vitamin E, sesamin, and sesamol, it promotes fat metabolism and nourishes the liver and kidneys. Unsaturated fatty acids, the main active ingredient, accelerate fat breakdown and metabolism, lower blood lipids, and prevent obesity and cardiovascular disease. It also improves dizziness, tinnitus, and premature graying of hair caused by liver and kidney deficiency, enhances immunity, and is suitable for daily health care for middle-aged and elderly people.

[0019] Lily: Contains colchicine, lilioside, polysaccharides, proteins, and amino acids. It can soothe the mind, moisten the lungs, and relieve coughs. Colchicine and lilioside are the main active ingredients, and they can alleviate anxiety, insomnia, and other mental symptoms, regulate nervous system function, reduce the psychological burden of those experiencing high work pressure, promote sleep, and aid psychological adjustment and physical recovery for those recovering from hypertension and heart disease. It also has a certain effect on relieving dry coughs and dry coughs without sputum, and improves respiratory function.

[0020] Chrysanthemum: Contains flavonoids (such as luteolin and apigenin), volatile oils (such as borneol and camphor), and chrysanthemum glycosides. It has anti-hypertensive, antioxidant, and heat-clearing and detoxifying properties. Flavonoids, as the main active ingredient, can dilate coronary arteries, increase coronary blood flow, lower blood pressure, and assist in the treatment of hypertension. It can also scavenge free radicals in the body, reduce inflammation, and alleviate discomfort caused by oxidative stress and inflammation, such as sore throat and red and swollen eyes.

[0021] Corn silk: Contains saponins, flavonoids, polysaccharides, alkaloids, and minerals. It has diuretic, detumescent, and metabolic regulating properties. Saponins, as the main active ingredient, promote renal excretion of water and electrolytes, alleviate edema symptoms, and help lower blood pressure. It is particularly effective for patients with hypertension and edema. It helps regulate blood sugar and lipid metabolism, promotes metabolic balance, and maintains cardiovascular health.

[0022] Schisandra chinensis: Contains schisandrin, schisandrin A, schisandrin B, polysaccharides, and volatile oils. Schisandrin is the primary active ingredient, known for its ability to boost immunity, provide antioxidant support, and improve cardiovascular function. It can enhance the body's nonspecific immune system, boost resistance, and prevent disease, making it suitable for the elderly and those with frail health. Schisandrin and other ingredients possess antioxidant properties, protect the cardiovascular system, regulate heart function, and improve symptoms like palpitations and chest tightness, offering a positive impact on those recovering from heart disease.

[0023] In another aspect, the present invention provides a danshen heart-protecting tea atomized liquid adapted for atomization equipment and a preparation method thereof, comprising the following steps:

[0024] S1 Weighing: Weigh the above-mentioned Chinese medicinal materials according to the weight ratio;

[0025] S2 Crushing: Pour the weighed Chinese medicine raw materials into the grinder and grind them into powder;

[0026] S3 sieving: the ground Chinese medicinal materials are passed through an 80-mesh sieve and subjected to boiling water reflux extraction for 1 hour;

[0027] S4 extraction: Filter the extract, add ethanol to the extract, and precipitate overnight to increase the ethanol concentration;

[0028] S5 concentration: The water-extracted alcohol precipitate is centrifuged to obtain a clear liquid, which is then vacuum concentrated to obtain the extract.

[0029] extract;

[0030] S6 dissolution: dissolving the extract with propylene glycol to prepare a propylene glycol solution;

[0031] S7 finished product: Glycerol is added to the propylene glycol solution, and the remaining weight is supplemented with propylene glycol to prepare the atomized liquid.

[0032] Furthermore, in step S4, ethanol needs to be added twice, and the two alcohol precipitations are carried out overnight.

[0033] Furthermore, in step S4, the ethanol concentration needs to be increased from 40% to 70%.

[0034] Furthermore, in step S7, glycerol is added, with the proportion of glycerol being 50%, and the remaining weight is supplemented by propylene glycol to obtain an atomized liquid.

[0035] Beneficial effects of the present invention

[0036] The present invention provides a Danshen Baoxin tea atomized liquid adapted for an atomization device and a preparation method thereof, which uses Danshen and green tea as core raw materials, and cooperates with various other Chinese medicinal materials for lowering blood lipids and blood pressure, regulating metabolism, protecting cardiovascular system, resisting oxidation and fatigue, and improving the body's immunity. Components such as Danshen and Eucommia ulmoides act synergistically on the cardiovascular system, while green tea and chrysanthemum assist in promoting microcirculation, while components such as black sesame and corn silk synergistically regulate lipid metabolism, and cooperate with Polygonum multiflorum to enhance the body's metabolic capacity, while green tea polyphenols and Schisandra chinensis form an antioxidant synergistic system, while components such as lily and Apocynum venetum synergistically soothe the nervous system. Their synergistic effect maximizes the use of their respective active ingredients, enhances the body's antioxidant capacity from different links, and prevents various chronic diseases. The active ingredients are efficiently delivered to the lungs through the atomization device, and have a faster absorption rate than traditional ingestion methods. It is particularly suitable for groups that require daily health care. DETAILED DESCRIPTION

[0037] To make the objectives, technical solutions and advantages of the present invention more clearly understood, the present invention is further described in detail below with reference to the embodiments. The embodiments of the present invention are only used to explain the present invention and are not intended to limit the present invention.

[0038] Example 1

[0039] A danshen heart-protecting tea atomization liquid suitable for atomization equipment comprises the following raw materials in parts by weight: 10g danshen, 5g green tea, 5g eucommia, 3g apocynum venetum, 5g sophora japonica flower, 5g polygonum multiflorum, 5g mistletoe, 8g black sesame, 6g lily, 3g chrysanthemum, 3g corn silk, and 3g schisandra chinensis.

[0040] A danshen heart-protecting tea atomized liquid suitable for atomization equipment and a preparation method thereof, comprising the following steps:

[0041] The Chinese medicinal materials were weighed in proportion by weight, poured into a grinder and ground into powder, the ground Chinese medicinal materials were sieved through an 80-mesh sieve, extracted with boiling water under reflux for 1 hour, the extract was filtered, ethanol was added to the extract twice, and the alcohol precipitation was carried out overnight twice to increase the ethanol concentration to 70%, the water-extracted alcohol precipitate was centrifuged to obtain a clear liquid, and the extract was concentrated under vacuum to obtain an extract, the extract was dissolved with propylene glycol to obtain a propylene glycol solution, glycerol was added to the propylene glycol solution, the glycerol accounted for 50%, and the remaining weight was supplemented with propylene glycol to obtain an atomized liquid.

[0042] Example 2

[0043] A danshen heart-protecting tea atomization liquid suitable for atomization equipment comprises the following raw materials in parts by weight: 15g danshen, 8g green tea, 7g eucommia, 5g apocynum venetum, 7g sophora japonica flower, 8g polygonum multiflorum, 8g mistletoe, 10g black sesame, 8g lily, 5g chrysanthemum, 5g corn silk, and 5g schisandra chinensis.

[0044] The preparation method is the same as that of Example 1.

[0045] Example 3

[0046] A danshen heart-protecting tea atomization liquid suitable for atomization equipment comprises the following raw materials in parts by weight: 20g danshen, 10g green tea, 10g eucommia, 8g apocynum venetum, 8g sophora japonica flower, 10g polygonum multiflorum, 10g mistletoe, 12g black sesame, 12g lily, 8g chrysanthemum, 8g corn silk, and 8g schisandra chinensis.

[0047] The preparation method is the same as that of Example 1.

[0048] Comparative Example 1 (without adding raw materials Salvia miltiorrhiza and green tea)

[0049] A Danshen heart-protecting tea atomization liquid suitable for atomization equipment comprises the following raw materials in parts by weight: 5g of Eucommia ulmoides, 3g of Apocynum venetum, 5g of Sophora japonica flower, 5g of Polygonum multiflorum, 5g of Morus alba, 8g of black sesame, 6g of lily, 3g of chrysanthemum, 3g of corn silk, and 3g of Schisandra chinensis.

[0050] The preparation method is the same as that of Example 1.

[0051] Comparative Example 2 (without adding raw material Salvia miltiorrhiza)

[0052] A danshen heart-protecting tea atomization liquid suitable for atomization equipment comprises the following raw materials in parts by weight: 8g green tea, 7g eucommia ulmoides, 5g apocynum venetum, 7g sophora japonica flower, 8g polygonum multiflorum, 8g mistletoe, 10g black sesame, 8g lily, 5g chrysanthemum, 5g corn silk, and 5g schisandra chinensis.

[0053] The preparation method is the same as that of Example 1.

[0054] Comparative Example 3 (without adding raw material green tea)

[0055] A danshen heart-protecting tea atomization liquid suitable for atomization equipment comprises the following raw materials in parts by weight: 20g danshen, 10g eucommia, 8g apocynum venetum, 8g sophora japonica flower, 10g polygonum multiflorum, 10g mistletoe, 12g black sesame, 12g lily, 8g chrysanthemum, 8g corn silk, and 8g schisandra chinensis.

[0056] The preparation method is the same as that of Example 1.

[0057] Experimental testing

[0058] Thirty people with hypertension or cardiovascular abnormalities, with systolic blood pressure ≥140 mmHg or diastolic blood pressure ≥90 mmHg, aged between 45 and 65 years, and regardless of gender, were recruited from the society. They were divided into 6 groups, with 5 people in each group. The first group used the nebulized liquid prepared in Example 1, the second group used the nebulized liquid prepared in Example 2, the third group used the nebulized liquid prepared in Example 3, the fourth group used the nebulized liquid prepared in Comparative Example 1, the fifth group used the nebulized liquid prepared in Comparative Example 2, and the sixth group used the nebulized liquid prepared in Comparative Example 3.

[0059] Nebulization method: three times a day, 15 minutes each time.

[0060] Time: Follow-up observation for 4 weeks, blood pressure test every 7 days, go to the hospital for a routine blood test, and do a sleep assessment.

[0061] Effective criteria: normal blood pressure, white blood cell count, red blood cell count, hemoglobin and platelet count in routine blood tests are all within reference values, good sleep (easy to fall asleep, no frequent waking up during the night, no fatigue the next day).

[0062] Table 1 Experimental effects of Examples 1-3 and Comparative Examples 1-3 on the test population

[0063]

[0064] It can be seen from the test in Table 1 that the people who inhaled the embodiment by atomization basically all had substantial improvement effects, while the people who inhaled the control sample lacking the core raw material had less ideal effects.

[0065] In summary, the present invention provides a danshen heart-protecting tea atomization liquid adapted for atomization equipment and a preparation method thereof, which uses danshen and green tea as core raw materials, utilizes the characteristics of green tea, and coordinates danshen and other raw materials in a scientific ratio to maximize their respective active ingredients, fully utilizing the technical advantages of atomization inhalation, so that the active ingredients in the tea are absorbed by the human body more quickly and efficiently, thereby achieving the effects of lowering blood pressure and lipids, regulating cardiovascular function, enhancing the body's antioxidant capacity, preventing chronic diseases, improving nervous system function, reducing stress, promoting sleep, and the like.

[0066] The embodiments of the present invention are only specific descriptions of the technical solutions, not limitations of the technical solutions. Any substitutions or modifications made by those skilled in the art without changing the essential contents of the present invention shall fall within the protection scope of the present invention.

Claims

1. A Danshen heart-protecting tea formula adapted for atomization equipment, characterized in that , at least contains the following raw material components: salvia miltiorrhiza and green tea.

2. The tea beverage formulation according to claim 1, characterized in that: The raw material components also include: Eucommia bark, Apocynum venetum, Sophora japonica flower, Polygonum multiflorum, Morus alba, black sesame, lily, chrysanthemum, corn silk and Schisandra chinensis.

3. The tea beverage formulation according to claim 2, characterized in that: It is prepared according to the following weight ratio: 10-20g of salvia miltiorrhiza, 5-10g of green tea, 5-10g of eucommia bark, 3-8g of apocynum venetum, 5-8g of sophora japonica flower, 5-10g of polygonum multiflorum, 5-10g of mistletoe, 8-12g of black sesame, 6-12g of lily, 3-8g of chrysanthemum, 3-8g of corn silk, and 3-8g of schisandra chinensis.

4. The tea beverage formulation according to claim 3, characterized in that: It is prepared according to the following weight ratio: 10g of Salvia miltiorrhiza, 5g of green tea, 5g of Eucommia ulmoides, 3g of Apocynum venetum, 5g of Sophora japonica flower, 5g of Polygonum multiflorum, 5g of Morus alba, 8g of black sesame, 6g of lily, 3g of chrysanthemum, 3g of corn silk, and 3g of Schisandra chinensis.

5. The tea beverage formulation according to claim 3, characterized in that: It is prepared according to the following weight ratio: 15g of Salvia miltiorrhiza, 8g of green tea, 7g of Eucommia ulmoides, 5g of Apocynum venetum, 7g of Sophora japonica flower, 8g of Polygonum multiflorum, 8g of Morus alba, 10g of black sesame, 8g of lily, 5g of chrysanthemum, 5g of corn silk, and 5g of Schisandra chinensis.

6. The tea beverage formulation according to claim 3, characterized in that: It is prepared according to the following weight ratio: 20g of Salvia miltiorrhiza, 10g of green tea, 10g of Eucommia ulmoides, 8g of Apocynum venetum, 8g of Sophora japonica flower, 10g of Polygonum multiflorum, 10g of Morus alba, 12g of black sesame, 12g of lily, 8g of chrysanthemum, 8g of corn silk, and 8g of Schisandra chinensis.

7. The method for preparing tea atomized liquid according to claim 2, characterized in that: The method comprises the following steps: S1 weighing: weighing the above-mentioned Chinese medicinal materials according to the weight ratio; S2 Crushing: Pour the weighed Chinese medicine raw materials into the grinder and grind them into powder; S3 sieving: the ground Chinese medicinal materials are passed through an 80-mesh sieve and subjected to boiling water reflux extraction for 1 hour; S4 extraction: Filter the extract, add ethanol to the extract, and precipitate overnight to increase the ethanol concentration; S5 concentration: The water-extracted alcohol precipitate is centrifuged to obtain a clear liquid, which is then vacuum concentrated to obtain an extract concentrate; S6 dissolution: dissolving the extract with propylene glycol to prepare a propylene glycol solution; S7 finished product: glycerol is added to the propylene glycol solution, and the remaining weight is supplemented with propylene glycol to obtain an atomized liquid.

8. The method for preparing the tea atomized liquid according to claim 7, characterized in that: In step S4, ethanol needs to be added twice, and the two alcohol precipitations are carried out overnight.

9. The method for preparing the tea atomized liquid according to claim 7, wherein: In step S4, the ethanol concentration needs to be increased from 40% to 70%.

10. The method for preparing the tea atomized liquid according to claim 7, characterized in that: In step S7, glycerol is added, the glycerol accounts for 50%, and the remaining weight is supplemented by propylene glycol to prepare an atomized liquid.

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