Nutritional supplement with stable performance and application

Abstract

The invention belongs to the technical field of nutritional supplements, and particularly relates to a nutritional supplement with stable performance and application thereof. The nutritional components comprise creatine monohydrate and a Chinese wolfberry fruit extract. Under a buffer system, the creatine monohydrate and the wolfberry extract in the nutritional supplement are mixed according to a ratio of (0.5-5): 1, so that the PCr and 1-RM power can be effectively improved, the decomposition of creatine can be greatly reduced, and a positive effect on maintaining active creatine is achieved. Experiments show that according to the nutritional composition, the increase amount of PCr is 14%-19%, the increase amount of 1-RM power is 6.1%-8.5%, the highest percentage of residual creatine can reach 94%-95%, and the content of active creatine is reserved to a great extent.

Description

Technical Field

[0001] The present invention belongs to the technical field of nutritional supplements, and in particular relates to a nutritional supplement with stable performance and application thereof. Background Art

[0002] Creatine monohydrate is a highly effective nutritional supplement known for enhancing muscle strength and athletic performance. Goji berry (Lycium barbarum), a fruit rich in antioxidants, vitamins, and polysaccharides, has traditionally been used to support immune function and overall health. While combining the health benefits of goji berry with the performance benefits of creatine is appealing, no supplement has previously been able to effectively achieve this in a single, stable product due to significant technical challenges. This challenge primarily stems from creatine's instability in acidic environments: when exposed to low pH conditions (pH < 6.0), creatine monohydrate undergoes intramolecular cyclization to form creatinine, an inactive and metabolically undesirable byproduct. This degradation accelerates significantly as pH decreases. This instability severely limits the formulation of creatine into liquid or semi-liquid products, such as ready-to-drink beverages or powdered drink mixes containing fruit ingredients.

[0003] Goji berry extracts and juices are naturally acidic due to the organic acids they contain. Furthermore, acidulants such as citric acid are often added to these products to improve flavor, further lowering the pH and accelerating creatine degradation. For example, creatine in a citric acid solution at room temperature can lose more than half its potency within a month. Studies have shown that even within a few days, creatine in solution can significantly degrade: after three days at 25°C, approximately 21% of creatine is converted to creatinine at pH 3.5 (compared to approximately 12% at pH 4.5). A bottle of creatine-containing fruit juice can lose most of its potency within a few weeks at room temperature, making it unsuitable for commercial distribution. This rapid degradation has, until now, hindered the development of creatine beverages or fruit-based supplement blends with long shelf lives.

[0004] Prior art attempts to address this stabilization issue have sought to avoid acidic environments altogether. One known approach involves adding a strong alkaline agent to raise the formulation's pH to a neutral or alkaline range (pH 7-14). While this approach effectively prevents creatine degradation, it is fundamentally incompatible with acidic fruit extracts like goji berries: raising the pH to such high levels neutralizes the fruit's desirable tart flavor and potentially degrades sensitive vitamins and phytonutrients present in goji berry extracts, resulting in an unpleasant product. Conversely, making the solution extremely acidic (pH <2.5) also prevents creatine degradation, but this is impractical for a palatable supplement. Currently, no existing products or references teach how to achieve creatine stability in a mildly acidic, fruit-containing matrix. Summary of the Invention

[0005] Based on this, the present application provides a nutritional supplement with stable performance and its application to solve the technical problem in the prior art that creatine is easily degraded when preparing nutritional supplements by combining wolfberry and creatine.

[0006] The technical solutions of this application to solve the above technical problems are as follows: A nutritional supplement with stable performance comprises: nutritional components and a buffer system, wherein the nutritional components comprise creatine monohydrate and wolfberry extract, wherein the mass ratio of the creatine monohydrate to the wolfberry extract is (0.5 to 5):1; and the mass ratio of the nutritional components to the buffer system is (5 to 15):1.

[0007] Preferably, in the above nutritional supplement with stable performance, the mass ratio of the creatine monohydrate to the wolfberry extract is (0.5 to 3):1.

[0008] Preferably, in the above-mentioned nutritional supplement with stable performance, the mass ratio of the nutritional components to the buffer system is (8 to 10):1.

[0009] Preferably, in the above-mentioned nutritional supplement with stable performance, the buffer system includes at least one of citric acid, sodium citrate, malic acid, tartaric acid, sodium tartrate and phosphate.

[0010] Preferably, in the above-mentioned nutritional supplement with stable performance, the buffer system includes citric acid, sodium citrate and malic acid.

[0011] Preferably, in the above-mentioned nutritional supplement with stable performance, in the buffer system, the mass ratio of citric acid, sodium citrate and malic acid is (1 to 5): (1 to 5): (0.3 to 1.5).

[0012] Preferably, in the above nutritional supplement with stable performance, the wolfberry extract contains more than 40% polysaccharides.

[0013] Preferably, the nutritional supplement with stable performance further comprises at least one of a flavoring agent, a sweetener and an anti-caking agent.

[0014] For use of the nutritional supplement with stable performance as described above, the nutritional supplement is dissolved in water and consumed.

[0015] Preferably, in the application of the above nutritional supplement, the mass ratio of the nutritional supplement to water is 1:(50 to 100).

[0016] Compared with the prior art, this application has at least the following advantages: The nutritional supplement disclosed in this application includes nutritional components and a buffer system, wherein the nutritional components include creatine monohydrate and wolfberry extract. In the buffer system, the creatine monohydrate and wolfberry extract in the nutritional supplement are mixed in a ratio of (0.5 to 5) : 1. This not only effectively improves PCr and 1-RM strength, but also significantly reduces creatine breakdown, which has a positive effect on maintaining active creatine. Experiments have shown that this nutritional composition increases PCr by 14% to 19% and 1-RM strength by 6.1% to 8.5%, and the residual creatine percentage can reach up to 94% to 95%, greatly retaining the active creatine content. DETAILED DESCRIPTION

[0017] It should be noted that, in the absence of conflict, the embodiments and features of the embodiments of the present invention can be combined with each other. The following will further describe the technical solution of the present invention in conjunction with the embodiments of the present invention, and the present invention is not limited to the following specific implementation methods.

[0018] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by those skilled in the art to which this application belongs. The terms used in the specification herein are for the purpose of describing specific embodiments only and are not intended to limit this application. The term "and / or" as used herein includes any and all combinations of one or more of the associated listed items.

[0019] In a specific embodiment of the present application, a nutritional supplement with stable performance includes: nutritional components and a buffer system, wherein the nutritional components include creatine monohydrate and wolfberry extract, and the mass ratio of the creatine monohydrate to the wolfberry extract is (0.5 to 5):1; the mass ratio of the nutritional components to the buffer system is (5 to 15):1.

[0020] The molecular formula of creatine monohydrate in this application is C4H 11 N₃O₃·H₂O has a molecular weight of 149.15. Goji berry extract, a chemically derived active ingredient extracted from the mature fruit of the Chinese wolfberry tree, includes polysaccharides, carotenoids, fat, protein, free amino acids, taurine, betaine, vitamin B1, vitamin B2, vitamin E, and vitamin C. In this application, the goji berry extract is preferably in a concentrated form, such as an extract standardized to a high polysaccharide content, to ensure consistency and efficacy. Therefore, the goji berry extract preferably contains greater than 40% polysaccharides, and further preferably, contains between 40% and 60% polysaccharides.

[0021] Experiments have found that when creatine monohydrate and wolfberry extract work together in the presence of a buffer system, they can not only significantly increase the level of phosphocreatine (PCr) in muscles and functional muscle strength (evaluated by 1-RM strength), but also greatly reduce the decomposition of active creatine, maintaining the content of active creatine at a higher level.

[0022] When the weight ratio of creatine monohydrate to wolfberry extract is (0.5 to 5):1, and the mass ratio of the nutritional components to the buffer system is (5 to 15):1, PCr can be increased by 14% to 19%, 1-RM strength can be increased by 6.1% to 8.5%, and the residual creatine percentage is above 80%.

[0023] Furthermore, the mass ratio of the creatine monohydrate to the wolfberry extract is (0.5 to 3):1. In a buffered system, this ratio significantly improves both PCr and 1-RM strength, and the residual creatine percentage reaches up to 94%, greatly preserving the active creatine content. Preferably, the mass ratio of the nutritional component to the buffer system is (8 to 10):1.

[0024] In a preferred embodiment, the buffer system includes at least one of citric acid, sodium citrate, malic acid, tartaric acid, sodium tartrate and phosphate.

[0025] Furthermore, the buffer system comprises citric acid, sodium citrate and malic acid. Citric acid and sodium citrate form a citric acid buffer pair, while malic acid broadens the buffering capacity and enhances the taste.

[0026] Furthermore, in the buffer system, the mass ratio of citric acid, sodium citrate and malic acid is (1 to 5): (1 to 5): (0.3 to 1.5).

[0027] In some embodiments, the nutritional supplement further comprises at least one of a flavoring agent, a sweetener, and an anti-caking agent.

[0028] In another specific embodiment of the present application, as for the use of the nutritional supplement with stable performance as described above, the nutritional supplement is dissolved in water and consumed.

[0029] Preferably, the nutritional supplement is used in a mass ratio of 1:50 to 100 (to water). When the nutritional supplement is dissolved in water (e.g., one part in 500 ml), the pH of the solution is approximately 3.0 to 4.0 due to the buffering agent. Control experiments have shown that in the absence of a buffer, the pH of a similar goji berry + creatine beverage (e.g., Experimental Group 1) drops below 3 (approximately 2.5-2.7), triggering rapid decomposition of creatine.

[0030] In practical applications, to achieve improved stability and uniformity in nutritional supplements, creatine monohydrate and wolfberry extract can be coated or encapsulated together using co-granulation and microencapsulation processes. These processes can include fluidized bed coating, spray drying, wet granulation, and extrusion granulation. Any process that can tightly bind creatine monohydrate, wolfberry extract, and a buffer system can achieve the purpose of microencapsulation, and is not specifically limited here. For example, the fluidized bed coating process is as follows: (1) Preparation of coating solution: A portion of wolfberry extract (rich in polysaccharides) is dissolved in water together with a buffer system to prepare a buffer solution with a pH value of approximately 4.0.

[0031] (2) Fluidized creatine granules: Fine creatine monohydrate powder is placed in a fluidized bed granulator / coating machine and the particles are suspended by warm air.

[0032] (3) Spray coating: The wolfberry / buffer solution is sprayed into a fluidized creatine bed. As the water evaporates, the wolfberry polysaccharides and buffer components form a protective coating or matrix around the creatine microcrystals. The multiple coatings accumulate layer by layer to form a cohesive shell around each creatine particle.

[0033] (4) Curing / Drying: The coated granules are further dried to remove residual moisture, thereby obtaining granules with good flowability, wherein each granule contains creatine intimately mixed with wolfberry solids and buffer.

[0034] (5) Final mixing: The resulting microencapsulated powder is mixed with any remaining ingredients.

[0035] This process uniquely utilizes the components of wolfberry extract itself as the encapsulation medium. The resulting microencapsulated particles have the following characteristics: Morphology (SEM): Substantially spherical, uniform particles, in contrast to the irregular, heterogeneous particles produced by simple dry mixing. Each particle contains both creatine monohydrate and wolfberry extract in a fixed ratio, along with a buffer system to prevent separation of the components.

[0036] Angle of repose: The angle of repose of microencapsulated granules is less than 35° and can reach 32°, indicating excellent flowability, while a simple dry mixture has an angle of repose of 48° and poor flowability. This makes microencapsulated granules ideal for filling into sachets or capsules, which is crucial for manufacturing and packaging.

[0037] Hygroscopicity (percent weight gain): After 48 hours at 75% relative humidity, the microencapsulated particles showed a hygroscopic weight gain of less than 3%, reaching 2.1%, compared to 9.5% for the simple dry mixture. This demonstrates a significant reduction in hygroscopicity, indicating that the wolfberry extract coating (lycium barbarum polysaccharide coating) effectively protects creatine from ambient moisture, reducing the risk of agglomeration and degradation during storage.

[0038] Chemical Protection: The creatine in each particle is protected from moisture and excess acidity before use. The LBP outer coating buffer acts as a barrier, enhancing stability during storage compared to unprotected creatine.

[0039] Taste masking: The Lycium barbarum polysaccharide coating helps mask the taste of creatine, with users primarily tasting the mild sweetness of the polysaccharide and the sourness of the buffer, improving the sensory properties.

[0040] Controlled Release: Encapsulation facilitates controlled or sustained release, which can improve absorption of nutrients and enhance their effectiveness.

[0041] Experiments comparing the microencapsulated product to a simple dry mixture of the same ingredients demonstrated that the encapsulated particles produced a granular powder with excellent flowability, were easy to pour, and exhibited no caking after storage. The simple mixture, on the other hand, was a fine powder that easily settled and compacted, exhibiting significant caking due to moisture absorption. Separation also occurred, with the lighter wolfberry extract floating and the heavier creatine monohydrate sinking, resulting in uneven content per spoonful. These observations confirmed that the microencapsulation process produces a product with superior physical properties, resolving the handling and caking issues critical to commercialization.

[0042] The nutritional supplement of the present invention can also be formulated as: Shelf-stable ready-to-drink (RTD) beverages: The microencapsulated particles can be suspended or dissolved in acidic juices or sports drinks, maintaining the pH at approximately 3.5 through a buffer system to prevent creatine degradation over time. This allows creatine beverages to have an extended shelf life (several months).

[0043] Powdered beverage mix with good flowability: The granulated microencapsulated granule powder can be packaged in bulk or single-serving sachets. Due to its reduced hygroscopicity, the microencapsulated granule powder can remain free-flowing and non-caking even in humid climates, and the content of each spoonful is uniform.

[0044] Capsules or tablets (solid dosage forms): Microencapsulated particles can be filled into capsules or compressed into tablets. Inside the capsule, creatine is protected from moisture and acid, allowing the two ingredients to coexist without degradation.

[0045] Chewable gummies or tablets: Stable microencapsulated particles can be incorporated into a gummies base or chewable tablets. The microencapsulation masks the bitter taste of creatine, giving the product a pleasant mouthfeel and goji berry fruit flavor, while the buffering system helps maintain a stable pH within the gummies.

[0046] The following is a detailed description of the technical solutions and effects of the present invention through specific experimental examples.

[0047] 1. Experimental Materials and Methods 1.1 Experimental Materials Creatine monohydrate: from Ningxia Hengkang Technology Co., Ltd., purity 98%.

[0048] Lycium barbarum extract: contains 50% Lycium barbarum polysaccharides, from Bairuiyuan Lycium barbarum Co., Ltd.

[0049] Citric acid, sodium citrate, malic acid, and other reagents were commercially available and used directly without further treatment.

[0050] Placebo drink: Red Bull.

[0051] 1.2 Experimental methods To evaluate changes in muscle phosphocreatine levels (PCr) and one-repetition maximum (1-RM) in recreational athletes during a 4-week supplementation period.

[0052] Four groups of five amateur athletes were recruited, all maintaining a consistent diet and exercise intensity. Key physiological parameters were measured before supplementation (baseline) and again after four weeks. The primary outcome measures were: Intramuscular creatine phosphate (PCr) levels, as measured by 31 P-Magnetic Resonance Spectroscopy ( 31 P-MRS) is a non-invasive measurement that reflects muscle energy storage capacity.

[0053] One-repetition maximum (1-RM) strength in the bench press, representing maximal force output, was calculated for each individual relative to their baseline to assess improvement.

[0054] Creatine stability was characterized by measuring the remaining active creatine concentration by HPLC at different time points after the supplement was dissolved in water and stored at 25°C for 28 days.

[0055] 2. Example 1 Comparative Group 1: Each person consumed 500ml of a placebo drink (Red Bull) daily to account for any training or psychological effects.

[0056] Comparative group 2: Each person took 4.5g of creatine monohydrate per day. The specific method was: 4.5g of creatine monohydrate was dissolved in 500ml of pure water and then drank.

[0057] At the same time, 4.5 g of creatine monohydrate was dissolved in 500 ml of purified water. The pH value of the resulting solution was measured to be 6.9. The solution was stored at 25°C for 28 days, and the remaining active creatine concentration was measured by HPLC.

[0058] Comparative Group 3: Each person took 4.5 g of wolfberry extract per day, specifically by dissolving 4.5 g of wolfberry extract in 500 ml of purified water and drinking it.

[0059] Experimental Group 1 : Each person took 4.5 g of the nutritional composition per day, specifically by dissolving 2.25 g of creatine monohydrate and 2.25 g of wolfberry extract in 500 ml of purified water and drinking it.

[0060] At the same time, 2.25 g of creatine monohydrate and 2.25 g of wolfberry extract were dissolved in 500 ml of purified water, and the pH of the resulting solution was measured to be 2.7. The solution was stored at 25°C for 28 days, and the remaining active creatine concentration was measured by HPLC.

[0061] Table 1 Average percent improvement from baseline after four weeks

[0062] See Table 1. Under consistent diet and exercise intensity, Comparative Group 1 took placebo beverages The group showed only trivial changes, confirming that the observed gains were due to the supplement and not training effects or measurement error. All differences were statistically significant for Experimental Group 1 compared to the placebo group (Comparative Group 1) and the individual component groups (Comparative Groups 2, 3), emphasizing that the benefits of the nutritional supplement were real and robust.

[0063] After four weeks of wolfberry extract for Comparative Group 3, there were no significant changes in average PCr and average 1-RM strength from baseline. While Comparative Group 2 showed significant increases in PCr and 1-RM strength with creatine monohydrate, Experimental Group 1, which took the nutritional composition of creatine monohydrate and wolfberry extract, increased muscle PCr by 19% and 1-RM strength by 7.2%, indicating that the wolfberry extract-creatine monohydrate combination facilitated enhanced phosphocreatine uptake or retention in muscle beyond what creatine monohydrate alone could achieve. This means that subjects who took the nutritional composition had more PCr in their muscles and provided greater strength gains than subjects who took the same amount of creatine without wolfberry, with an effect greater than the sum of Comparative Groups 2 and 3.

[0064] However, merely mixing creatine monohydrate and wolfberry extract and dissolving the mixture in water results in a rapid decrease in active creatine concentration, with only 49% of active creatine remaining after 14 days and only 35% of active creatine remaining after 28 days. This instability presents a barrier to the preparation of nutritional supplements from creatine monohydrate and wolfberry extract, as the combination of the two must overcome the decrease in active creatine concentration in order to achieve the desired effects of increasing PCr and 1-RM strength. Furthermore, this instability presents a significant limitation to the formulation of the combination as a liquid or semi-liquid product, such as a ready-to-drink beverage or a powdered beverage mix that can be combined with additional or alternative fruit ingredients at a later time.

[0065] 3. Example Two Each person consumed 5 g of the nutritional supplement per day, including 4.5 g of the nutritional component and 0.5 g of the buffer system, wherein the nutritional component included the amounts of creatine monohydrate and wolfberry extract indicated in Table 2 and the buffer system included 0.2 g of citric acid, 0.2 g of sodium citrate, and 0.1 g of malic acid. The nutritional supplement was consumed by dissolving 5 g of the nutritional supplement in 500 ml of purified water and drinking the solution.

[0066] In addition, 5 g of the nutritional supplement was dissolved in 500 ml of purified water, and the pH of the resulting solution was measured and stored at 25 °C for 28 days. The remaining active creatine concentration was measured by HPLC.

[0067] Table 2 Average Percent Improvement from Baseline After Four Weeks

[0068] As can be seen from the above table, when the total daily intake of the nutritional composition is kept constant, the effects on the human body vary depending on the ratio of creatine monohydrate to wolfberry extract in the nutritional supplement. Based on the same total intake, the intake of either creatine monohydrate (Example 2) or wolfberry extract (Example 7) being less than the other four examples results in a slightly lower increase in PCr and 1-RM strength than the other four examples, but a higher increase than the intake of creatine monohydrate alone (Comparison 2). The most effective example is Example 5, in which the ratio of creatine monohydrate to wolfberry extract is 2:1, with an average increase in PCr of 19%, which is 7% higher and a 58.3% increase than the intake of creatine monohydrate alone (Comparison 2), and an average increase in 1-RM strength of 8.5%, which is 3% higher and a 54.5% increase than the intake of creatine monohydrate alone.

[0069] In terms of the percentage of residual creatine, the percentage of residual creatine in the experimental groups above was above 80% at 28 days, which was a significant improvement compared to Experimental Group 1. This indicates that combining creatine monohydrate with wolfberry extract under buffer system conditions can greatly reduce the decomposition of creatine and has a positive effect on maintaining active creatine. However, as can be seen from the above table, the percentage of residual creatine varies when the ratio of creatine monohydrate to wolfberry extract is different, indicating that the ratio of creatine monohydrate to wolfberry extract also affects the decomposition of creatine.

[0070] In Experimental Group 5, which demonstrated the best performance in both PCr and 1-RM strength gains, its residual creatine percentage at 28 days was less than 90%, comparable to Experimental Groups 4, 5, and 7. In contrast, Experimental Group 6, while not as effective as Experimental Group 5 in terms of PCr and 1-RM strength gains, surprisingly, had a 94% residual creatine percentage at 28 days, far exceeding that of the other experimental groups. Therefore, considering both the improvement in PCr and 1-RM strength, as well as the residual creatine percentage, Experimental Group 6, with its creatine monohydrate to wolfberry extract ratio of 2.5:1, demonstrated the best overall performance.

[0071] 3. Example 3 5 g of the nutritional supplement, comprising 4.5 g of the nutritional components and 0.5 g of the buffer system (see Table 3 for specific components and amounts), was dissolved in 500 ml of purified water. The pH of the resulting solution is shown in the table below. The solution was stored at 25°C for 28 days, and the remaining active creatine concentration was measured by HPLC.

[0072] Table 3 Remaining active creatine concentration after four weeks

[0073] Referring to Table 3, the same nutritional components as those used in Experimental Group 5, which achieved significant increases in PCr and 1-RM strength, and those used in Experimental Group 6, which achieved the best overall performance, were selected as research subjects. When only the ratio of citric acid, citric acid, and malic acid in the buffer system was varied, the residual creatine percentage also varied. In Example 2, when the ratio of citric acid, citric acid, and malic acid was 2:2:1, the residual creatine percentage in Experimental Group 6 reached 94%, significantly higher than in the other experimental groups. However, in this example, when this ratio was varied, the residual creatine percentages in Experimental Groups 11, 12, and 13 (which had the same nutritional components as Experimental Group 6) were not as high as expected. Surprisingly, when the ratio of citric acid, citric acid, and malic acid was 2:4:1.5, the residual creatine percentage in Experimental Group 9 (which had the same nutritional components as Experimental Group 5) reached 95% at 28 days, significantly higher than in the other components. This shows that when the total amount is constant, the nutritional components and the buffer system jointly affect the comprehensive performance of the nutritional supplement: when the ratio of creatine monohydrate to wolfberry extract in the nutritional components is 2:1, and the ratio of citric acid, citric acid, and malic acid is 2:4:1.5, the comprehensive performance of the nutritional supplement is optimal; when the ratio of creatine monohydrate to wolfberry extract is 2.5:1, and the ratio of citric acid, citric acid, and malic acid is 2:2:1, the comprehensive performance of the nutritional supplement is optimal.

[0074] The above embodiments merely illustrate several implementation methods of the present application. While the descriptions are relatively specific and detailed, they should not be construed as limiting the scope of the patent application. It should be noted that a person of ordinary skill in the art may make various modifications and improvements without departing from the spirit of the present application, all of which fall within the scope of protection of the present application. Therefore, the scope of protection of the present patent application shall be determined by the appended claims.

Claims

1. A nutritional supplement with stable performance, characterized in that: include: The nutritional components and the buffer system include creatine monohydrate and wolfberry extract, the mass ratio of the creatine monohydrate to the wolfberry extract is (0.5 to 5):1; the mass ratio of the nutritional components to the buffer system is (5 to 15):

1.

2. The nutritional supplement with stable performance according to claim 1, characterized in that: The mass ratio of the creatine monohydrate to the wolfberry extract is (0.5 to 3):

1.

3. The nutritional supplement with stable performance according to claim 1, characterized in that: The mass ratio of the nutritional components to the buffer system is (8 to 10):

1.

4. The nutritional supplement with stable performance according to claim 1, wherein The buffer system includes at least one of citric acid, sodium citrate, malic acid, tartaric acid, sodium tartrate and phosphate.

5. The nutritional supplement with stable performance according to claim 1 or 4, characterized in that: The buffer system includes citric acid, sodium citrate and malic acid.

6. The nutritional supplement with stable performance according to claim 5, characterized in that: In the buffer system, the mass ratio of citric acid, sodium citrate and malic acid is (1 to 5): (1 to 5): (0.3 to 1.5).

7. The nutritional supplement with stable performance according to claim 1, wherein: The wolfberry extract contains more than 40% polysaccharides.

8. The nutritional supplement with stable performance according to claim 1, wherein: The nutritional supplement further includes at least one of a flavoring agent, a sweetener, and an anti-caking agent.

9. The use of the nutritional supplement with stable performance according to any one of claims 1 to 8, characterized in that: Dissolve the nutritional supplement in water and drink it.

10. The use of the nutritional supplement according to claim 9, characterized in that: The mass ratio of the nutritional supplement to water is 1:(50 to 100).

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