Joint prosthesis and preparation method thereof

Abstract

The invention relates to a joint prosthesis and a preparation method thereof, the joint prosthesis comprises a 3D printing joint prosthesis, the 3D printing joint prosthesis comprises a prosthesis joint and a prosthesis handle connected with the prosthesis joint, and the surface of the prosthesis joint is sprayed with polyether-ether-ketone. After the surface of the 3D printed joint prosthesis reaches the preheating temperature, polyether-ether-ketone powder is sprayed to the surface of the prosthesis joint through flame spraying, a firm, hard and compact polyether-ether-ketone coating with a crystal structure is formed on the surface of the prosthesis joint, mutual contact of the bone joint surfaces is facilitated, and the joint surface of the joint is protected; and meanwhile, the biocompatibility of the medical metal can be utilized for the non-sprayed part. In the actual use process, the contact surface is the contact between the polyether-ether-ketone and the cartilage, the friction factor is reduced to about 0.235, and the smoothness of the contact surface is greatly improved. And meanwhile, the polyether-ether-ketone has a water lubrication characteristic, is beneficial to the flow of interstitial fluid on the surface, has better lubricity than a medical metal surface, and is more beneficial to the surface contact between the implant and an original bone tissue.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and in particular to a joint prosthesis and a preparation method thereof. Background Art

[0002] 3D-printed joint prostheses are specially designed for patients with bone tumors or various bone and joint diseases. The prosthesis can be customized completely according to the patient's limb defect. 3D printing technology can directly convert design data into models or products. It has the advantages of high precision and rapid prototyping, and can realize customized 3D-printed joint prostheses for patients.

[0003] Currently, commonly used 3D printing materials are alloy materials such as titanium alloys. Although titanium and titanium alloys are currently the best biometal materials, they still have excessively large elastic modulus and their biomechanical properties do not match those of human bone tissue (the elastic modulus of human bone tissue is 3 to 18 GPa, while the elastic modulus of titanium alloy is 110 GPa). Moreover, even if the joint surface of a 3D-printed prosthesis based on an alloy is polished smoothly, its high hardness will still accelerate articular cartilage damage and degeneration.

[0004] In addition, the friction coefficients of the medical titanium alloy surfaces with different pore structures printed by 3D are all above 0.3, which is very different from the friction coefficient of 0.0113 of natural articular cartilage. It is easy to produce boundary friction at the joint connection, and even dry friction in severe cases. Summary of the Invention

[0005] In order to solve the above-mentioned technical problems, a joint prosthesis and a preparation method thereof are provided.

[0006] The technical means adopted in the present invention are as follows:

[0007] A joint prosthesis includes a 3D printed joint prosthesis. The 3D printed joint prosthesis includes a prosthetic joint and a prosthetic handle connected thereto. The surface of the prosthetic joint is sprayed with polyetheretherketone.

[0008] Furthermore, the joint prosthesis is used to replace the following joints in the human body caused by degenerative osteoarthritis, traumatic arthritis, arthritis caused by rheumatic autoimmune diseases, joint diseases caused by ischemic necrosis, bone tumors and soft tissue tumors leading to joint destruction and defects: shoulder joint prosthesis, elbow joint prosthesis, wrist joint prosthesis, finger joint prosthesis, hip joint prosthesis, knee joint prosthesis, ankle joint prosthesis, toe joint prosthesis, intervertebral disc prosthesis and bone defect bone grafting pad.

[0009] Furthermore, the material of the 3D printed joint prosthesis includes pure titanium, titanium alloy (Ti6Al4V), pure tantalum, and tantalum alloy.

[0010] Furthermore, the contact surface of the 3D printed joint prosthesis is designed to have a 3D printed grid structure with a pore diameter of 400 to 700 μm and a porosity of 40 to 60%.

[0011] Furthermore, the polyetheretherketone is sprayed on the surface of the prosthetic joint of the 3D printed joint prosthesis by flame spraying, so that the contact surface of the prosthetic joint is completely covered by the polyetheretherketone.

[0012] The present invention also provides a method for preparing the joint prosthesis, comprising the following steps:

[0013] Preparation of 3D printed joint prostheses;

[0014] PEEK pretreatment;

[0015] Preheating the prosthetic joint surface of the 3D printed joint prosthesis;

[0016] Using flame spraying to spray polyetheretherketone onto the surface of the prosthetic joint of the 3D printed joint prosthesis;

[0017] Polish the sprayed surface.

[0018] Furthermore, the preparation of the 3D printed joint prosthesis includes the following steps:

[0019] Obtain data of the joint prosthesis to be customized, use three-dimensional multi-planar reconstruction technology to establish a virtual model of the 3D printed joint prosthesis, and use a 3D printer to manufacture the customized 3D printed joint prosthesis.

[0020] Furthermore, after the 3D printed joint prosthesis is prepared, the following steps are also included:

[0021] The surface of the prosthetic joint of the 3D printed joint is sandblasted. After the sandblasting is completed, the dust on the sandblasted surface is blown away with dry, oil-free, clean compressed air.

[0022] Furthermore, the polyetheretherketone pretreatment comprises the following steps:

[0023] The original polyetheretherketone powder is dried in a blast drying oven at a drying temperature of 60-80°C, then the dried polyetheretherketone is weighed and mixed with anhydrous ethanol, and ultrasonically dispersed for 2-4 hours, followed by drying in a water bath at 70-90°C, and then drying in a blast drying oven at 60-70°C for 5-7 hours, then grinding into powder, and then drying the powder in a drying oven for 5-6 hours. The particle size of the polyetheretherketone powder ranges from 20 to 120 μm.

[0024] Furthermore, preheating the prosthetic joint surface of the 3D printed joint prosthesis includes the following steps:

[0025] Using acetylene (propane) as the fuel gas, the flame spraying equipment is turned on and the fuel gas is ignited to preheat the joint surface of the 3D printed joint prosthesis to a temperature of 230-390°C.

[0026] The method of spraying polyetheretherketone on the surface of the prosthetic joint of the 3D printed joint prosthesis by flame spraying specifically comprises the following steps:

[0027] During the spraying process, the powder feeding device of the flame spraying is turned on, and clean compressed gas with a temperature of 100 to 180°C is used as the powder feeding gas. The compressed gas is air, so that the polyetheretherketone powder is transported to the outlet of the powder feeder through the atomization vibration of the powder feeder, and leaves the powder feeding barrel together with the powder feeding gas and enters the spray gun. The spray gun is at an angle of 60 to 90° to the substrate and moves at a distance of 15 to 20 cm from the substrate. The pressure of the fuel gas is controlled to be 0.14 to 0.25 MPa, the flow rate of the fuel gas is 1 to 4 L / min, the fuel gas is acetylene, the oxygen pressure is 0.3 to 0.7 MPa, the flow rate of oxygen is 0.75 to 2 L / min, the pressure of the powder feeding gas is 0.3 to 0.4 MPa, the speed of the spray gun movement is controlled to be 200 to 300 mm / s, and a polyetheretherketone coating with a thickness of 0.5 to 1 mm is sprayed.

[0028] Furthermore, after spraying, the following steps are also included:

[0029] The sprayed surface is polished using silicon carbide sandpaper with mesh sizes of 240, 400, 600, 800, 1000 and 1200 in sequence.

[0030] The present invention utilizes flame spraying technology to manufacture a polyetheretherketone joint surface for a 3D-printed joint prosthesis. This process applies polyetheretherketone powder to the joint surface of the 3D-printed joint prosthesis using flame spraying, forming a firm, hard, dense coating with a crystalline structure on the joint surface. In this way, the sprayed area can utilize the excellent properties of polyetheretherketone, while the unsprayed area can utilize the excellent properties of the metal matrix.

[0031] Compared to existing technologies, the present invention offers the following advantages: After the 3D-printed joint prosthesis surface reaches preheating temperature, polyetheretherketone (PEEK) powder is flame-sprayed onto the prosthetic joint surface. Only the prosthetic joint surface is sprayed, leaving the rest of the prosthesis unsprayed. This results in a strong, hard, dense, and crystalline PEEK coating on the prosthetic joint surface, facilitating contact between the bone joint surfaces. Furthermore, the unsprayed areas can utilize the biocompatibility of medical metals, facilitating integration with human bone. The elastic modulus of human bone tissue is 3 to 18 GPa, while that of PEEK is 3 to 4 GPa. The surface elastic modulus of the 3D-printed joint prosthesis joint surface is reduced to approximately 3 to 18 GPa, more closely matching the elastic modulus and surface hardness of human bone tissue, which is beneficial to bone health around the connection end. At the interface where PEEK contacts cartilage, the friction coefficient drops to approximately 0.235, significantly improving the smoothness of the contact surface. At the same time, polyetheretherketone has water lubrication properties, which is beneficial to the flow of tissue fluid on the surface. It is more lubricating than medical metal surfaces and is more beneficial to the surface contact between implants and native bone tissue. BRIEF DESCRIPTION OF THE DRAWINGS

[0032] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the following briefly introduces the drawings required for use in the embodiments or the description of the prior art. Obviously, the drawings described below are some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying any creative labor.

[0033] Figure 1 The figure is a flow chart of the specific preparation method of the present invention. DETAILED DESCRIPTION

[0034] It should be noted that, in the absence of conflict, the embodiments and features of the embodiments of the present invention can be combined with each other. The present invention will be described in detail below with reference to the accompanying drawings and in combination with the embodiments.

[0035] In order to make the purpose, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. The following description of at least one exemplary embodiment is actually only illustrative and is in no way intended to limit the present invention and its application or use. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the present invention.

[0036] It should be noted that the terms used herein are only for describing specific embodiments and are not intended to limit the exemplary embodiments according to the present invention. As used herein, unless the context clearly indicates otherwise, the singular form is intended to include the plural form. In addition, it should be understood that when the terms "comprise" and / or "include" are used in this specification, they indicate the presence of features, steps, operations, devices, components and / or combinations thereof.

[0037] Unless otherwise specifically stated, the relative arrangement of the parts and steps, numerical expressions and numerical values ​​described in these embodiments do not limit the scope of the present invention. At the same time, it should be clear that, for ease of description, the sizes of the various parts shown in the drawings are not drawn according to the actual proportional relationship. The techniques, methods and equipment known to ordinary technicians in the relevant fields may not be discussed in detail, but where appropriate, the techniques, methods and equipment should be considered as part of the authorization specification. In all examples shown and discussed here, any specific value should be interpreted as merely exemplary and not as a limitation. Therefore, other examples of the exemplary embodiments may have different values. It should be noted that similar numbers and letters represent similar items in the following figures, so once an item is defined in one figure, it does not need to be further discussed in subsequent figures.

[0038] In the description of the present invention, it should be understood that the directions or positional relationships indicated by directional words such as "front, back, up, down, left, right", "horizontal, vertical, vertical, horizontal" and "top, bottom" are usually based on the directions or positional relationships shown in the accompanying drawings. They are only for the convenience of describing the present invention and simplifying the description. Unless otherwise specified, these directional words do not indicate or imply that the device or element referred to must have a specific direction or be constructed and operated in a specific direction. Therefore, they cannot be understood as limiting the scope of protection of the present invention: the directional words "inside and outside" refer to the inside and outside relative to the outline of each component itself.

[0039] For ease of description, spatially relative terms such as "above", "above", "on the upper surface of", "above", etc. may be used herein to describe the spatial positional relationship of a device or feature to other devices or features as shown in the figures. It should be understood that spatially relative terms are intended to include different orientations of the device in use or operation in addition to the orientation described in the figures. For example, if the device in the drawings is inverted, the device described as "above other devices or structures" or "above other devices or structures" will be positioned as "below other devices or structures" or "below their position devices or structures". Thus, the exemplary term "above" can include both "above" and "below". The device can also be positioned in other different ways (rotated 90 degrees or in other orientations), and the spatially relative descriptions used here are interpreted accordingly.

[0040] In addition, it should be noted that the use of terms such as "first" and "second" to limit components is only for the convenience of distinguishing the corresponding components. Unless otherwise stated, the above terms have no special meaning and therefore cannot be understood as limiting the scope of protection of the present invention.

[0041] Embodiments of the present invention disclose a joint prosthesis, including a 3D-printed joint prosthesis comprising a prosthetic joint and a connected prosthetic stem, the surface of which is spray-coated with polyetheretherketone. This invention reduces the surface hardness of the prosthetic joint surface while improving its lubricity, thereby reducing articular cartilage damage and degeneration.

[0042] Furthermore, the material of the 3D printed joint prosthesis includes pure titanium, titanium alloy (Ti6Al4V), pure tantalum, and tantalum alloy.

[0043] Furthermore, the contact surface of the 3D printed joint prosthesis is designed to have a 3D printed grid structure with a pore diameter of 400 to 700 μm and a porosity of 40 to 60%.

[0044] Furthermore, the polyetheretherketone is sprayed on the surface of the prosthetic joint of the 3D printed joint prosthesis by flame spraying, so that the contact surface of the prosthetic joint is completely covered by the polyetheretherketone.

[0045] like Figure 1 As shown, the present invention also provides a method for preparing the above-mentioned joint prosthesis, comprising the following steps:

[0046] Preparation of 3D printed joint prostheses;

[0047] PEEK pretreatment;

[0048] Preheating the prosthetic joint surface of the 3D printed joint prosthesis;

[0049] Using flame spraying to spray polyetheretherketone onto the surface of the prosthetic joint of the 3D printed joint prosthesis;

[0050] Polish the sprayed surface.

[0051] The above method uses flame spraying to coat polyetheretherketone powder on the joint surface of a 3D-printed joint prosthesis, forming a firm, hard, dense coating with a crystalline structure on the joint surface. In this way, the sprayed area can utilize the excellent properties of polyetheretherketone, while the unsprayed area can utilize the excellent properties of the metal matrix.

[0052] Furthermore, the preparation of the 3D printed joint prosthesis includes the following steps:

[0053] Obtain data of the joint prosthesis to be customized, use three-dimensional multi-planar reconstruction technology (Mimics) to create a virtual model of the 3D printed joint prosthesis, and use a 3D printer to manufacture the customized 3D printed joint prosthesis.

[0054] In this embodiment, based on the preoperative data acquisition and image processing of the patient, customized three-dimensional reconstruction measurement and prosthetic component design are performed on the 3D printed joint prosthesis.

[0055] Furthermore, after the 3D printed joint prosthesis is prepared, the following steps are also included:

[0056] The surface of the prosthetic joint of the 3D printed joint is sandblasted. After the sandblasting is completed, the dust on the sandblasted surface is blown away with dry, oil-free, clean compressed air.

[0057] The fresh surface after sandblasting must not be contaminated again. Finger marks left by touching will affect the bonding of the sprayed coating. Spraying should be done as soon as possible after sandblasting to prevent the substrate from absorbing moisture or oxidation, which may affect the bonding performance of the coating.

[0058] Furthermore, the polyetheretherketone pretreatment comprises the following steps:

[0059] The original powder of polyetheretherketone is dried in a blast drying oven at a drying temperature of 60-80°C, and then the dried polyetheretherketone is weighed and mixed with anhydrous ethanol, and ultrasonically dispersed for 2 hours or more, followed by drying in an 80°C water bath, and then drying in a blast drying oven at 60°C for more than 6 hours, and then grinding into powder, and then drying the powder in a drying oven for 5-6 hours. The particle size range of the polyetheretherketone powder is 20-120 μm.

[0060] Furthermore, preheating the prosthetic joint surface of the 3D printed joint prosthesis includes the following steps:

[0061] Acetylene (propane) is used as the fuel gas, the flame spraying equipment is turned on, the fuel gas is ignited, and the joint surface of the 3D printed joint prosthesis is preheated to a temperature of 230 to 390°C.

[0062] The method of spraying polyetheretherketone on the surface of the prosthetic joint of the 3D printed joint prosthesis by flame spraying specifically comprises the following steps:

[0063] During the spraying process, the flame spray powder feeding device is turned on, and clean compressed gas at 100-180°C is used as the powder feeding gas. The compressed gas is air, so that the polyetheretherketone powder is transported to the powder feeder outlet through the atomization vibration of the powder feeder, and leaves the powder feeding barrel together with the powder feeding gas and enters the spray gun. The spray gun is at an angle of 60-90° to the substrate and moves at a distance of 15-20 cm from the substrate. The fuel gas pressure is controlled to be 0.14-0.25 MPa, the fuel gas flow rate is 1-4 L / min, the fuel gas is acetylene, the oxygen pressure is 0.3-0.7 MPa, the oxygen flow rate is 0.75-2 L / min, the powder feeding gas pressure is 0.3-0.4 MPa, and the spray gun movement speed is controlled to be 200-300 mm / s. A polyetheretherketone coating with a thickness of 0.5-1 mm is sprayed, and the coating surface has a smooth morphology. During the flame spraying process of polyetheretherketone, spraying can be carried out by manual spray gun or automatic spraying equipment.

[0064] Specifically, the spraying area is only the joint surface 1 of the 3D printed joint prosthesis, and the 3D printed joint prosthesis stem 2 does not need to be flame sprayed. This allows the joint surface of the 3D printed joint prosthesis to form a firm, hard, dense, and crystalline polyetheretherketone coating, which is beneficial to the mutual contact of the bone joint surfaces. At the same time, the unsprayed area can utilize the biocompatibility of medical metals to facilitate integration with human bones.

[0065] Furthermore, after spraying, the following steps are also included:

[0066] Polish the sprayed surface using silicon carbide sandpaper of 240, 400, 600, 800, 1000, and 1200 meshes in order to reduce the surface friction coefficient and meet the requirements of bio-modification after polishing.

[0067] The polishing process is divided into rough polishing and fine polishing.

[0068] Example 1

[0069] Step 1: Select an existing common 3D printed joint prosthesis bracket model. The model can be divided into a 3D printed joint prosthesis and a prosthesis stem. The base material is titanium alloy, the diameter of the prosthesis joint contact surface gap is 500 μm, and the porosity of the 3D printed joint prosthesis is 50%.

[0070] 2. First, sandblast the surface of the 3D printed joint prosthesis. After sandblasting, use dry, oil-free, clean compressed air to blow away the dust on the sandblasted surface.

[0071] 3. The 20 μm polyetheretherketone powder was dried in a blast drying oven at 60°C, and then the dried polyetheretherketone was weighed and mixed with anhydrous ethanol, and ultrasonically dispersed for 3 hours, followed by drying in a 70°C water bath, and then dried in a blast drying oven at 50°C for 7 hours, then ground into powder, and the powder was dried in a drying oven for 5 hours.

[0072] 4. Use acetylene as the fuel gas, turn on the flame spraying equipment, ignite the fuel gas, and preheat the joint surface of the 3D printed joint prosthesis to 300°C.

[0073] 5. After the surface of the 3D-printed joint prosthesis reaches 300°C, polyetheretherketone (PEEK) powder is flame-sprayed onto the joint surface. The stem is not flame-sprayed. During the spraying process, the flame spray powder feeder is activated, using clean compressed air at 180°C as the feed gas. The PEEK powder is atomized and vibrated by the powder feeder to the outlet. The powder, along with the feed gas, exits the feeder barrel and enters the spray gun. The spray gun is positioned at a 60° angle to the substrate and moves 15 cm from the substrate. The acetylene pressure is maintained at 0.25 MPa, the oxygen pressure at 0.7 MPa, the acetylene flow rate at 4 L / min, the oxygen flow rate at 2 L / min, and the feed gas pressure at 0.4 MPa. The spray gun movement speed is controlled at 300 mm / s, resulting in a 0.5 mm thick PEEK coating with a smooth surface. Automatic spraying equipment is used for the PEEK flame spraying process.

[0074] 6. After the 3D printed joint prosthesis polyetheretherketone joint surface is flame sprayed, the 3D printed joint prosthesis joint surface (1) is coarsely polished, and silicon carbide sandpaper with mesh sizes of 240, 400, 600, 800, 1000, and 1200 is used for step-by-step polishing. After coarse polishing, the 3D printed joint prosthesis polyetheretherketone joint surface is cleaned and placed in a clean environment to air dry. The preliminary preparation of the 3D printed joint prosthesis polyetheretherketone joint surface is completed.

[0075] Example 2

[0076] Step 1. Select an existing common 3D printed joint prosthesis bracket model. The model can be divided into a 3D printed joint prosthesis joint and a 3D printed joint prosthesis stem. The base material is tantalum alloy, the contact surface gap diameter of the prosthesis joint is 400 μm, and the porosity is 40%.

[0077] 2. First, sandblast the surface of the 3D printed joint prosthesis. After sandblasting, use dry, oil-free, clean compressed air to blow away the dust on the sandblasted surface.

[0078] 3. The 40 μm polyetheretherketone original powder was dried in a blast drying oven at 70°C, and then the dried polyetheretherketone was weighed and mixed with anhydrous ethanol, and ultrasonically dispersed for 2 hours, followed by drying in an 80°C water bath, and then dried in a blast drying oven at 60°C for 5 hours, then ground into powder, and the powder was dried in a drying oven for 5 hours.

[0079] 4. Using propane as the fuel gas, turn on the flame spraying equipment, ignite the fuel gas, and preheat the joint surface of the 3D printed joint prosthesis to 390°C.

[0080] 5. When the surface temperature of the joint prosthesis reaches 390°C, flame spraying is used to spray polyetheretherketone powder onto the joint surface of the 3D printed joint prosthesis (1). The 3D printed joint prosthesis stem (2) does not require flame spraying.

[0081] During the spraying process, the flame spray powder feeding device is turned on, and clean compressed air at 180°C is used as the powder feeding gas. The polyetheretherketone powder is transported to the powder feeder outlet through the atomization vibration of the powder feeder. Together with the powder feeding gas, it leaves the powder feeding barrel and enters the spray gun. The spray gun is at a 70° angle to the substrate and moves at a distance of 20 cm from the substrate. The acetylene pressure is controlled at 0.14 MPa, the oxygen pressure is 0.7 MPa, the acetylene flow rate is 1.5 L / min, the oxygen flow rate is 1 L / min, the powder feeding gas pressure is 0.4 MPa, and the spray gun movement speed is controlled at 200 mm / s. A 0.75 mm thick polyetheretherketone coating is sprayed, and the coating surface has a smooth morphology. During the polyetheretherketone flame spraying process, automatic spraying equipment is used for spraying.

[0082] 6. After the 3D printed joint prosthesis polyetheretherketone joint surface is flame sprayed, the 3D printed joint prosthesis joint surface (1) is coarsely polished, and silicon carbide sandpaper with mesh sizes of 240, 400, 600, 800, 1000, and 1200 is used for step-by-step polishing. After coarse polishing, the 3D printed joint prosthesis polyetheretherketone joint surface is cleaned and placed in a clean environment to air dry. The preliminary preparation of the 3D printed joint prosthesis polyetheretherketone joint surface is completed.

[0083] Example 3

[0084] Step 1: Select an existing common 3D printed joint prosthesis bracket model. The model can be divided into a prosthetic joint surface and a prosthetic stem. The base material is pure tantalum, the pore diameter of the prosthetic joint contact surface is 700 μm, and the porosity is 60%.

[0085] 2. First, sandblast the surface of the 3D printed joint prosthesis. After sandblasting, use dry, oil-free, clean compressed air to blow away the dust on the sandblasted surface.

[0086] 3. The 120 μm polyetheretherketone original powder was dried in a blast drying oven at 90°C, and then the dried polyetheretherketone was weighed and mixed with anhydrous ethanol, and ultrasonically dispersed for 2.5 hours, followed by drying in a 90°C water bath, and then dried in a blast drying oven at 70°C for 5 hours, then ground into powder, and the powder was dried in a drying oven for 6 hours.

[0087] 4. Use acetylene as the fuel gas, turn on the flame spraying equipment, ignite the fuel gas, and preheat the joint surface of the 3D printed joint prosthesis to 230°C.

[0088] 5. When the surface temperature of the 3D printed joint prosthesis reaches 230°C, flame spraying is used to spray polyetheretherketone powder on the surface of the prosthesis joint (1), while flame spraying is not used for the 3D printed joint prosthesis stem (2).

[0089] During the spraying process, the flame spray powder feeding device is turned on, and clean compressed air at 180°C is used as the powder feeding gas. The polyetheretherketone powder is transported to the powder feeder outlet through the atomization vibration of the powder feeder. Together with the powder feeding gas, it leaves the powder feeding barrel and enters the spray gun. The spray gun is at a 90° angle to the substrate and moves at a distance of 18 cm from the substrate. The acetylene pressure is controlled at 0.15 MPa, the oxygen pressure is 0.7 MPa, the acetylene flow rate is 2 L / min, the oxygen flow rate is 1 L / min, the powder feeding gas pressure is 0.4 MPa, and the spray gun movement speed is controlled at 200 mm / s. A 1 mm thick polyetheretherketone coating is sprayed, and the coating surface has a smooth morphology. During the polyetheretherketone flame spraying process, automatic spraying equipment is used for spraying.

[0090] 6. After the 3D printed joint prosthesis polyetheretherketone joint surface is flame sprayed, the joint surface (1) of the joint prosthesis is roughly polished, and silicon carbide sandpaper with mesh sizes of 240, 400, 600, 800, 1000, and 1200 is used for step-by-step polishing. After the rough polishing, the joint surface of the prosthesis polyetheretherketone is cleaned and placed in a clean environment to air dry. The preliminary preparation of the joint surface of the 3D printed joint prosthesis polyetheretherketone is completed.

[0091] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit it. Although the present invention has been described in detail with reference to the above embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the above embodiments, or replace some or all of the technical features therein with equivalents. However, these modifications or replacements do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of the present invention.

Claims

1. A joint prosthesis, characterized in that: The invention comprises a 3D printed joint prosthesis, wherein the 3D printed joint prosthesis comprises a prosthetic joint and a prosthetic handle connected thereto, and the surface of the prosthetic joint is sprayed with polyetheretherketone.

2. The joint prosthesis according to claim 1, characterized in that The joint prosthesis is used to replace the following joints in the human body caused by degenerative osteoarthritis, traumatic arthritis, arthritis caused by rheumatic autoimmune diseases, joint diseases caused by ischemic necrosis, bone tumors and soft tissue tumors that lead to joint destruction and defects: shoulder joint prosthesis, elbow joint prosthesis, wrist joint prosthesis, finger joint prosthesis, hip joint prosthesis, knee joint prosthesis, ankle joint prosthesis, toe joint prosthesis, intervertebral disc prosthesis and bone defect bone grafting pad.

3. The joint prosthesis according to claim 1, characterized in that The materials of the 3D printed joint prosthesis include pure titanium, titanium alloy, pure tantalum, and tantalum alloy.

4. The joint prosthesis according to claim 1, characterized in that The contact surface of the 3D printed joint prosthesis is designed with a 3D printed grid structure with a pore diameter of 400-700 μm and a porosity of 40-60%.

5. The joint prosthesis according to claim 1, characterized in that The polyetheretherketone is sprayed on the surface of the prosthetic joint of the 3D printed joint prosthesis by flame spraying, so that the contact surface of the prosthetic joint is completely covered by the polyetheretherketone.

6. A method for preparing a joint prosthesis according to any one of claims 1 to 5, characterized in that: The steps include: Preparation of 3D printed joint prostheses; PEEK pretreatment; Preheating the prosthetic joint surface of the 3D printed joint prosthesis; Using flame spraying to spray polyetheretherketone onto the surface of the prosthetic joint of the 3D printed joint prosthesis; Polish the sprayed surface.

7. The method according to claim 6, characterized in that The preparation of the 3D printed joint prosthesis comprises the following steps: Obtain data of the joint prosthesis to be customized, use three-dimensional multi-planar reconstruction technology to establish a virtual model of the 3D printed joint prosthesis, and use a 3D printer to manufacture the customized 3D printed joint prosthesis.

8. The method according to claim 6, characterized in that After the 3D printed joint prosthesis is prepared, the following steps are also included: The surface of the prosthetic joint of the 3D printed joint is sandblasted. After the sandblasting is completed, the dust on the sandblasted surface is blown away with dry, oil-free, clean compressed air.

9. The method according to claim 6, characterized in that The polyetheretherketone pretreatment comprises the following steps: The original polyetheretherketone powder is dried in a blast drying oven at a drying temperature of 60-80°C, then the dried polyetheretherketone is weighed and mixed with anhydrous ethanol, and ultrasonically dispersed for 2-4 hours, followed by drying in a water bath at 70-90°C, and then drying in a blast drying oven at 60-70°C for 5-7 hours, then grinding into powder, and then drying the powder in a drying oven for 5-6 hours. The particle size of the polyetheretherketone powder ranges from 20 to 120 μm.

10. The method according to claim 6, characterized in that Preheating the prosthetic joint surface of a 3D printed joint prosthesis includes the following steps: Turn on the flame spraying equipment, ignite the fuel gas, and preheat the joint surface of the 3D printed joint prosthesis to a temperature of 230-390°C; The method of spraying polyetheretherketone on the surface of the prosthetic joint of the 3D printed joint prosthesis by flame spraying specifically comprises the following steps: During the spraying process, the powder feeding device of the flame spraying is turned on, and clean compressed gas with a temperature of 100 to 180°C is used as the powder feeding gas. The compressed gas is air, so that the polyetheretherketone powder is transported to the outlet of the powder feeder through the atomization vibration of the powder feeder, and leaves the powder feeding barrel together with the powder feeding gas and enters the spray gun. The spray gun is at an angle of 60 to 90° to the substrate and moves at a distance of 15 to 20 cm from the substrate. The pressure of the fuel gas is controlled to be 0.14 to 0.25 MPa, the flow rate of the fuel gas is 1 to 4 L / min, the fuel gas is acetylene, the oxygen pressure is 0.3 to 0.7 MPa, the flow rate of oxygen is 0.75 to 2 L / min, the pressure of the powder feeding gas is 0.3 to 0.4 MPa, the speed of the spray gun movement is controlled to be 200 to 300 mm / s, and a polyetheretherketone coating with a thickness of 0.5 to 1 mm is sprayed.

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