Weight-losing L-carnitine tea polyphenol conjugated linoleic acid soft capsule and preparation method thereof

Abstract

The invention discloses a weight-losing soft capsule and a preparation method thereof. The weight-losing soft capsule is prepared from a capsule content and a glue solution, wherein the capsule content is prepared from the following raw materials in parts by weight: 30-50 parts of L-carnitine, 5-20 parts of tea polyphenol, 45-60 parts of conjugated linoleic acid, 2-6 parts of beewax and 2-10 parts of prebiotics; the glue solution is prepared from the following raw materials in parts by weight: 20-50 parts of gelatin, 10-20 parts of glycerol, 20-50 parts of water and 0.5-1 part of a stabilizer. The preparation method comprises the following steps: pressing the prepared glue solution and capsule contents into soft capsules in a soft capsule machine, pelleting, washing pills, drying and the like, and packaging and warehousing. According to the soft capsule prepared by the invention, the fat energy supply proportion is increased, the body metabolism state is optimized by improving the mitochondrial function and the lactic acid removal efficiency, a more efficient energy metabolism mode is provided for fat reduction, and the soft capsule is good in palatability and has a good commercial prospect.

Description

Technical Field

[0001] This invention belongs to the field of food processing and relates to a weight-loss L-carnitine tea polyphenol conjugated linoleic acid soft capsule and its preparation method. Background Art

[0002] Currently, there are many health foods on the market that have weight loss and health care functions. Usually, weight loss soft capsules are health foods made mainly from L-carnitine combined with plant extracts or certain functional ingredients.

[0003] CN113975335A discloses a composition for controlling appetite and inducing satiety, comprising extracts of coffee beans, hibiscus, saffron, and L-carnitine. This composition, by controlling appetite and inducing satiety, can regulate the feeding center of the brain-gut axis, thereby achieving a fat-reducing effect. CN104146263A discloses a weight-loss soft capsule prepared from contents and a gel. The contents mainly include L-carnitine, tea polyphenols, and conjugated linoleic acid; the gel mainly includes gelatin, glycerin, and black iron oxide. This weight-loss soft capsule can promote fat metabolism and decomposition, and has the effects of weight loss and beauty enhancement. Currently, weight-loss soft capsule products still have considerable room for optimization in terms of stability, palatability, and fat-reducing efficacy. In-depth research or improvement can be carried out from the dimensions of formulation process and technological innovation. Summary of the Invention

[0004] Given the limited variety and palatability of existing technical solutions, this invention discloses a weight-loss L-carnitine, tea polyphenol, and conjugated linoleic acid soft capsule, prepared from capsule contents and a gel. The capsule contents are composed of the following ingredients by weight: 30-50 parts L-carnitine, 5-20 parts tea polyphenols, 45-60 parts conjugated linoleic acid, 2-6 parts beeswax, and 2-10 parts prebiotics. The gel is composed of the following ingredients by weight: 20-50 parts gelatin, 10-20 parts glycerin, 20-50 parts water, and 0.5-1 part stabilizer.

[0005] A method for preparing a weight-loss L-carnitine, tea polyphenol, and conjugated linoleic acid soft capsule includes the following steps:

[0006] (1) Preparation of adhesive solution: Stir and heat 10-20 parts of glycerin, 20-50 parts of water and 0.5-1 parts of stabilizer in a dissolving tank to 70-80°C, add 20-50 parts of gelatin and stir until the gelatin is completely dissolved; vacuum the adhesive solution mixture for 20-30 minutes, sieve and let stand to obtain the adhesive solution;

[0007] (2) Preparation of capsule contents: Mix 30-50 parts of L-carnitine, 5-20 parts of tea polyphenols and 2-10 parts of prebiotics through a 100-mesh sieve and set aside; heat 5-15 parts of conjugated linoleic acid to 50-80℃, add 2-6 parts of beeswax to melt, add the remaining conjugated linoleic acid and stir, add the mixed powder, stir and mix for 10-30 minutes, pass through a colloid mill 1-3 times, and after degassing, the capsule contents are obtained.

[0008] (3) Capsule pressing: The contents of the capsule and the gel are pressed into soft capsules in a soft capsule machine and then shaped.

[0009] (4) Drying: Place the prepared soft capsules in a drying tray and dry them at a temperature of 20-26℃ for 18-20 hours;

[0010] (5) Selecting capsules: After drying, the soft capsules are inspected on a light inspection table to remove unqualified soft capsules such as irregularly shaped capsules, bubble capsules, capsules of different sizes, and capsules with oil leakage;

[0011] (6) Inner packaging, outer packaging and warehousing: Take qualified soft capsules, bottle them, then package the product according to the packaging requirements, affix labels, and then pack them in cartons. Once they pass the inspection, they are considered finished products. Finally, the finished products should be placed in a cool and dry warehouse.

[0012] The stabilizer is prepared as follows:

[0013] Add 0.1-2 parts soybean lecithin and 0.1-2 parts functional additives to 3-8 parts water and stir at 800-1000 r / min for 20-50 min at room temperature; add 0.5-3 parts black iron oxide, premix at 100-200 r / min for 3-5 min, then increase the speed to 300-800 r / min and heat to 50-80℃, stir for 10-30 min; add 0.5-3 parts glycerol, adjust the colloid mill gap to 15 μm and grind 4 times; vacuum dry for 1-5 h to obtain the final product.

[0014] The preparation method of the weight-loss L-carnitine tea polyphenol conjugated linoleic acid soft capsules involves a sieve-sieving, static, and heat-preserving treatment, which means passing the gelatin solution through a 100-mesh sieve, allowing it to stand for 24 hours, and maintaining a temperature of 50-60℃.

[0015] The functional adjuvant involved in the preparation method of the weight-loss L-carnitine tea polyphenol conjugated linoleic acid soft capsule is at least one of glyceryl monostearate, glyceryl hexanoate, glyceryl caprylate, and ceramide-3; the functional adjuvant is selected as a mixture of glyceryl caprylate and ceramide-3.

[0016] The prebiotics involved in the preparation method of the weight-loss L-carnitine tea polyphenol conjugated linoleic acid soft capsules are any one of fructooligosaccharides, xylooligosaccharides, and galactooligosaccharides; the prebiotics are selected as a mixture of xylooligosaccharides and galactooligosaccharides.

[0017] The vacuum drying process involved in the preparation method of the weight-loss L-carnitine tea polyphenol conjugated linoleic acid soft capsules refers to drying at 20 kPa and 45°C for 1-5 hours.

[0018] The compression molding process involved in the preparation method of the weight-loss L-carnitine tea polyphenol conjugated linoleic acid soft capsules refers to placing the compressed soft capsules in a rotating drum and molding them for 4 hours at a temperature of 18-24℃.

[0019] Conjugated linoleic acid: As an oily matrix, it can slow down the release rate of L-carnitine, activate fat breakdown, and improve overall fat loss efficiency.

[0020] Prebiotics: The added oligosaccharides, through a triple mechanism of complementary molecular structure, optimized rheological properties, and synergistic bioactivity, significantly improve the powder dispersibility in fat-soluble contents, enhancing the overall stability of the soft capsules and the sustainability of the fat-reducing effect.

[0021] The beneficial effects of this invention are:

[0022] 1. Compared with the prior art, the present invention provides a weight loss L-carnitine tea polyphenol conjugated linoleic acid soft capsule, which regulates the expression of lipid metabolism genes through the "L-carnitine-tea polyphenol-conjugated linoleic acid" ternary synergistic system, significantly promotes fat metabolism and decomposition, and enhances the weight loss effect; at the same time, tea polyphenols have certain beauty and skin care functions, meeting the needs of modern people for healthy weight loss.

[0023] 2. This invention employs a unique preparation process for the soft capsule solution, including the preparation of black iron oxide-phospholipid composite powder and the addition of prebiotics. This significantly improves the dispersibility of the powder in the capsule contents, enhancing the stability and palatability of the soft capsules. The black iron oxide-phospholipid composite powder inhibits particle sedimentation by forming a steric hindrance layer, strengthening the interfacial bonding between the inorganic filler and the organic matrix. The addition of prebiotics optimizes rheological properties, improving the stability of the soft capsules during storage and processing. Simultaneously, the soft capsules possess excellent palatability, are easy to take and absorb, and improve user compliance. Detailed Implementation

[0024] The specific preparation method for L-carnitine, tea polyphenols, and conjugated linoleic acid soft capsules for weight loss is as follows:

[0025] (1) Preparation of adhesive solution: Add 200-500g water, 100-200g glycerin and 5-10g stabilizer to a gelling tank and heat to 70-80℃. Add 200-500g gelatin and stir at 200r / min for 12min. Vacuum for about 30min until there are no bubbles in the adhesive solution. Pass the adhesive solution through a 100-mesh sieve. Let stand for 24h and keep warm at 50-60℃ to obtain the adhesive solution.

[0026] (2) Preparation of capsule contents: Mix 300-500g of L-carnitine, 50-200g of tea polyphenols and 20-100g of prebiotics through a 100-mesh sieve and set aside; heat 50-150g of conjugated linoleic acid to 50-80℃, add 20-60g of beeswax to melt, add the remaining conjugated linoleic acid and stir, add the prepared mixture powder, stir and mix for 10-30 minutes, pass through a colloid mill 1-3 times, and after degassing, the capsule contents are obtained;

[0027] (3) Capsule pressing: The contents of the capsule and the gel are pressed into soft capsules in a soft capsule machine with a filling amount of 0.5g / capsule; the pressed soft capsules are placed in a rotating drum and set at room temperature for 3-6 hours.

[0028] (4) Drying: Place the prepared soft capsules in a drying tray and dry them at a temperature of 20-26℃ for 18-20 hours;

[0029] (5) Selecting capsules: After drying, the soft capsules are inspected on a light inspection table to remove unqualified soft capsules such as irregularly shaped capsules, bubble capsules, capsules of different sizes, and capsules with oil leakage;

[0030] (6) Inner packaging, outer packaging and warehousing: Take qualified soft capsules, bottle them, then package the product according to the packaging requirements, affix labels, and then pack them in cartons. Once they pass the inspection, they are considered finished products. Finally, the finished products should be placed in a cool and dry warehouse.

[0031] The stabilizer is prepared as follows:

[0032] Add 1-20g of soybean lecithin and 1-20g of functional additives to 30-80g of water and stir at 800-1000r / min for 20-50min at room temperature; add 5-30g of black iron oxide, premix at 100-200r / min for 3-5min, then increase the speed to 300-800r / min and heat to 50-80℃, stir for 10-30min; add 5-30g of glycerol, adjust the colloid mill gap to 15μm and grind 4 times; dry at 20KPa and 45℃ for 1-5h to obtain the final product.

[0033] Soybean phospholipids: Phospholipids anchor the surface of black iron oxide particles through their hydrophobic ends and extend outwards through their hydrophilic ends to form a steric hindrance layer, which inhibits particle sedimentation. The non-polar segments are compatible with polymer matrices such as beeswax and conjugated linoleic acid, which enhances the interfacial bonding between inorganic fillers and organic matrices.

[0034] Functional additives: synergistically encapsulate L-carnitine with phospholipids, reducing gastric acid damage and improving intestinal absorption; protect conjugated linoleic acid from oxidation and deterioration during processing and storage.

[0035] Ceramides: With an amphiphilic structure, they can synergistically work with phospholipids to enhance the efficiency of micromicelle encapsulation of fat-soluble components such as conjugated linoleic acid and tea polyphenols in the intestine; combined with prebiotics, they are more easily absorbed and utilized by the human body.

[0036] The parameters and sources of some substances in the examples are as follows:

[0037] Black iron oxide: CAS No.: 1317-61-9; iron oxide content ≥96%, food grade.

[0038] Glyceryl monostearate: CAS No.: 123-94-4, food grade.

[0039] Glyceryl hexanoate: CAS No.: 621-70-5, food grade.

[0040] Caprylic / capric triglyceride: CAS No.: 65381-09-1, food grade.

[0041] Ceramide-3: CAS No.: 100403-19-8; derived from rice bran, food grade.

[0042] Fructooligosaccharides: CAS No.: 308066-66-2, molecular weight 180.156, food grade.

[0043] Xylooligosaccharide: CAS No.: 87-99-0; molecular weight: 300; food grade.

[0044] Galacto-oligosaccharides: CAS No.: 6587-31-1; molecular weight 300, food grade.

[0045] Example 1

[0046] Weight loss soft capsules containing L-carnitine, tea polyphenols, and conjugated linoleic acid are prepared from capsule contents and a gel, as follows:

[0047] (1) Preparation of adhesive solution: 300g water, 120g glycerin and 6g black iron oxide are stirred and heated to 80℃ in a gelling tank. 300g gelatin is added and stirred at 200r / min for 12min. Vacuum is applied for about 30min until there are no bubbles in the adhesive solution. The adhesive solution is passed through a 100-mesh sieve. The solution is allowed to stand for 24h and kept at 60℃ to obtain the adhesive solution.

[0048] (2) Preparation of capsule contents: Mix 340g of L-carnitine and 100g of tea polyphenols through a 100-mesh sieve and set aside; heat 100g of conjugated linoleic acid to 70℃, add 40g of beeswax to melt, add 420g of conjugated linoleic acid and stir, add the prepared mixture powder, stir and mix for 20min, pass through a colloid mill twice, and after degassing, the capsule contents are obtained;

[0049] (3) Capsule pressing: The contents of the capsule and the gel are pressed into soft capsules in a soft capsule machine with a filling amount of 0.5g / capsule; the pressed soft capsules are placed in a rotating drum and set at a temperature of 24℃ for 4 hours.

[0050] (4) Drying: Place the prepared soft capsules in a drying tray and dry them at 25°C for 18 hours;

[0051] (5) Selecting capsules: After drying, the soft capsules are inspected on a light inspection table to remove unqualified soft capsules such as irregularly shaped capsules, bubble capsules, capsules of different sizes, and capsules with oil leakage;

[0052] (6) Inner packaging, outer packaging and warehousing: Take qualified soft capsules, bottle them, then package the product according to the packaging requirements, affix labels, and then pack them in cartons. Once they pass the inspection, they are considered finished products. Finally, the finished products should be placed in a cool and dry warehouse.

[0053] Example 2

[0054] Weight loss soft capsules containing L-carnitine, tea polyphenols, and conjugated linoleic acid are prepared from capsule contents and a gel, as follows:

[0055] (1) Preparation of adhesive solution: 300g water, 120g glycerin and 6g black iron oxide-phospholipid composite powder are stirred and heated to 80℃ in a gelling tank. 300g gelatin is added and stirred at 200r / min for 12min. Vacuum is applied for about 30min until there are no bubbles in the adhesive solution. The adhesive solution is passed through a 100-mesh sieve. The solution is allowed to stand for 24h and kept at 60℃ to obtain the adhesive solution.

[0056] (2) Preparation of capsule contents: Mix 340g of L-carnitine and 100g of tea polyphenols through a 100-mesh sieve and set aside; heat 100g of conjugated linoleic acid to 70℃, add 40g of beeswax to melt, add 420g of conjugated linoleic acid and stir, add the prepared mixture powder, stir and mix for 20min, pass through a colloid mill twice, and after degassing, the capsule contents are obtained;

[0057] (3) Capsule pressing: The contents of the capsule and the gel are pressed into soft capsules in a soft capsule machine with a filling amount of 0.5g / capsule; the pressed soft capsules are placed in a rotating drum and set at a temperature of 24℃ for 4 hours.

[0058] (4) Drying: Place the prepared soft capsules in a drying tray and dry them at 25°C for 18 hours;

[0059] (5) Selecting capsules: After drying, the soft capsules are inspected on a light inspection table to remove unqualified soft capsules such as irregularly shaped capsules, bubble capsules, capsules of different sizes, and capsules with oil leakage;

[0060] (6) Inner packaging, outer packaging and warehousing: Take qualified soft capsules, bottle them, then package the product according to the packaging requirements, affix labels, and then pack them in cartons. Once they pass the inspection, they are considered finished products. Finally, the finished products should be placed in a cool and dry warehouse.

[0061] The preparation of the black iron oxide-phospholipid composite powder is as follows:

[0062] Add 16g of soybean lecithin to 45g of water and stir at 1000r / min for 30min at room temperature. Add 10g of black iron oxide and premix at 200r / min for 5min. Then increase the speed to 500r / min and heat to 60℃ and stir for 30min. Add 10g of glycerol and grind 4 times with the colloid mill gap adjusted to 15μm. Dry at 20KPa and 45℃ for 3h to obtain the final product.

[0063] Example 3

[0064] Weight loss soft capsules containing L-carnitine, tea polyphenols, and conjugated linoleic acid are prepared from capsule contents and a gel, as follows:

[0065] (1) Preparation of adhesive solution: 300g water, 120g glycerin and 6g black iron oxide-phospholipid composite powder are stirred and heated to 80℃ in a gelling tank. 300g gelatin is added and stirred at 200r / min for 12min. Vacuum is applied for about 30min until there are no bubbles in the adhesive solution. The adhesive solution is passed through a 100-mesh sieve. The solution is allowed to stand for 24h and kept at 60℃ to obtain the adhesive solution.

[0066] (2) Preparation of capsule contents: Mix 340g of L-carnitine and 100g of tea polyphenols through a 100-mesh sieve and set aside; heat 100g of conjugated linoleic acid to 70℃, add 40g of beeswax to melt, add 420g of conjugated linoleic acid and stir, add the prepared mixture powder, stir and mix for 20min, pass through a colloid mill twice, and after degassing, the capsule contents are obtained;

[0067] (3) Capsule pressing: The contents of the capsule and the gel are pressed into soft capsules in a soft capsule machine with a filling amount of 0.5g / capsule; the pressed soft capsules are placed in a rotating drum and set at a temperature of 24℃ for 4 hours.

[0068] (4) Drying: Place the prepared soft capsules in a drying tray and dry them at 25°C for 18 hours;

[0069] (5) Selecting capsules: After drying, the soft capsules are inspected on a light inspection table to remove unqualified soft capsules such as irregularly shaped capsules, bubble capsules, capsules of different sizes, and capsules with oil leakage;

[0070] (6) Inner packaging, outer packaging and warehousing: Take qualified soft capsules, bottle them, then package the product according to the packaging requirements, affix labels, and then pack them in cartons. Once they pass the inspection, they are considered finished products. Finally, the finished products should be placed in a cool and dry warehouse.

[0071] The preparation of the black iron oxide-phospholipid composite powder is as follows:

[0072] Add 8g of soybean lecithin and 8g of glyceryl monostearate to 45g of water and stir at 1000r / min for 30min at room temperature. Add 10g of black iron oxide and premix at 200r / min for 5min. Then increase the speed to 500r / min and heat to 60℃, stirring for 30min. Add 10g of glycerol and grind 4 times with the colloid mill gap adjusted to 15μm. Dry at 20KPa and 45℃ for 3h to obtain the final product.

[0073] Example 4

[0074] Weight loss soft capsules containing L-carnitine, tea polyphenols, and conjugated linoleic acid are prepared from capsule contents and a gel, as follows:

[0075] (1) Preparation of adhesive solution: 300g water, 120g glycerin and 6g black iron oxide-phospholipid composite powder are stirred and heated to 80℃ in a gelling tank. 300g gelatin is added and stirred at 200r / min for 12min. Vacuum is applied for about 30min until there are no bubbles in the adhesive solution. The adhesive solution is passed through a 100-mesh sieve. The solution is allowed to stand for 24h and kept at 60℃ to obtain the adhesive solution.

[0076] (2) Preparation of capsule contents: Mix 340g of L-carnitine and 100g of tea polyphenols through a 100-mesh sieve and set aside; heat 100g of conjugated linoleic acid to 70℃, add 40g of beeswax to melt, add 420g of conjugated linoleic acid and stir, add the prepared mixture powder, stir and mix for 20min, pass through a colloid mill twice, and after degassing, the capsule contents are obtained;

[0077] (3) Capsule pressing: The contents of the capsule and the gel are pressed into soft capsules in a soft capsule machine with a filling amount of 0.5g / capsule; the pressed soft capsules are placed in a rotating drum and set at a temperature of 24℃ for 4 hours.

[0078] (4) Drying: Place the prepared soft capsules in a drying tray and dry them at 25°C for 18 hours;

[0079] (5) Selecting capsules: After drying, the soft capsules are inspected on a light inspection table to remove unqualified soft capsules such as irregularly shaped capsules, bubble capsules, capsules of different sizes, and capsules with oil leakage;

[0080] (6) Inner packaging, outer packaging and warehousing: Take qualified soft capsules, bottle them, then package the product according to the packaging requirements, affix labels, and then pack them in cartons. Once they pass the inspection, they are considered finished products. Finally, the finished products should be placed in a cool and dry warehouse.

[0081] The preparation of the black iron oxide-phospholipid composite powder is as follows:

[0082] Add 8g of soybean lecithin and 8g of hexanoic acid glyceride to 45g of water and stir at 1000r / min for 30min at room temperature. Add 10g of black iron oxide and premix at 200r / min for 5min. Then increase the speed to 500r / min and heat to 60℃ and stir for 30min. Add 10g of glycerol and grind 4 times with the colloid mill gap adjusted to 15μm. Dry at 20KPa and 45℃ for 3h to obtain the final product.

[0083] Example 5

[0084] Weight loss soft capsules containing L-carnitine, tea polyphenols, and conjugated linoleic acid are prepared from capsule contents and a gel, as follows:

[0085] (1) Preparation of adhesive solution: 300g water, 120g glycerin and 6g black iron oxide-phospholipid composite powder are stirred and heated to 80℃ in a gelling tank. 300g gelatin is added and stirred at 200r / min for 12min. Vacuum is applied for about 30min until there are no bubbles in the adhesive solution. The adhesive solution is passed through a 100-mesh sieve. The solution is allowed to stand for 24h and kept at 60℃ to obtain the adhesive solution.

[0086] (2) Preparation of capsule contents: Mix 340g of L-carnitine and 100g of tea polyphenols through a 100-mesh sieve and set aside; heat 100g of conjugated linoleic acid to 70℃, add 40g of beeswax to melt, add 420g of conjugated linoleic acid and stir, add the prepared mixture powder, stir and mix for 20min, pass through a colloid mill twice, and after degassing, the capsule contents are obtained;

[0087] (3) Capsule pressing: The contents of the capsule and the gel are pressed into soft capsules in a soft capsule machine with a filling amount of 0.5g / capsule; the pressed soft capsules are placed in a rotating drum and set at a temperature of 24℃ for 4 hours.

[0088] (4) Drying: Place the prepared soft capsules in a drying tray and dry them at 25°C for 18 hours;

[0089] (5) Selecting capsules: After drying, the soft capsules are inspected on a light inspection table to remove unqualified soft capsules such as irregularly shaped capsules, bubble capsules, capsules of different sizes, and capsules with oil leakage;

[0090] (6) Inner packaging, outer packaging and warehousing: Take qualified soft capsules, bottle them, then package the product according to the packaging requirements, affix labels, and then pack them in cartons. Once they pass the inspection, they are considered finished products. Finally, the finished products should be placed in a cool and dry warehouse.

[0091] The preparation of the black iron oxide-phospholipid composite powder is as follows:

[0092] Add 8g of soybean lecithin and 8g of caprylic / capric glyceride to 45g of water and stir at 1000r / min for 30min at room temperature. Add 10g of black iron oxide and premix at 200r / min for 5min. Then increase the speed to 500r / min and heat to 60℃ and stir for 30min. Add 10g of glycerol and grind 4 times with the colloid mill gap adjusted to 15μm. Dry at 20KPa and 45℃ for 3h to obtain the final product.

[0093] Example 6

[0094] Weight loss soft capsules containing L-carnitine, tea polyphenols, and conjugated linoleic acid are prepared from capsule contents and a gel, as follows:

[0095] (1) Preparation of adhesive solution: 300g water, 120g glycerin and 6g black iron oxide-phospholipid composite powder are stirred and heated to 80℃ in a gelling tank. 300g gelatin is added and stirred at 200r / min for 12min. Vacuum is applied for about 30min until there are no bubbles in the adhesive solution. The adhesive solution is passed through a 100-mesh sieve. The solution is allowed to stand for 24h and kept at 60℃ to obtain the adhesive solution.

[0096] (2) Preparation of capsule contents: Mix 300g L-carnitine, 100g tea polyphenols and 60g oligofructose through a 100-mesh sieve and set aside; heat 100g conjugated linoleic acid to 70℃, add 40g beeswax to melt, add 420g conjugated linoleic acid and stir, add the prepared mixture powder, stir and mix for 20min, pass through a colloid mill twice, and degas to obtain the capsule contents;

[0097] (3) Capsule pressing: The contents of the capsule and the gel are pressed into soft capsules in a soft capsule machine with a filling amount of 0.5g / capsule; the pressed soft capsules are placed in a rotating drum and shaped at a temperature of 24℃ for 4 hours; (4) Drying: the prepared soft capsules are placed in a drying tray and dried at a temperature of 25℃ for 18 hours.

[0098] (5) Selecting capsules: After drying, the soft capsules are inspected on a light inspection table to remove unqualified soft capsules such as irregularly shaped capsules, bubble capsules, capsules of different sizes, and capsules with oil leakage;

[0099] (6) Inner packaging, outer packaging and warehousing: Take qualified soft capsules, bottle them, then package the product according to the packaging requirements, affix labels, and then pack them in cartons. Once they pass the inspection, they are considered finished products. Finally, the finished products should be placed in a cool and dry warehouse.

[0100] The preparation of the black iron oxide-phospholipid composite powder is as follows:

[0101] Add 8g of soybean lecithin and 8g of caprylic / capric glyceride to 45g of water and stir at 1000r / min for 30min at room temperature. Add 10g of black iron oxide and premix at 200r / min for 5min. Then increase the speed to 500r / min and heat to 60℃ and stir for 30min. Add 10g of glycerol and grind 4 times with the colloid mill gap adjusted to 15μm. Dry at 20KPa and 45℃ for 3h to obtain the final product.

[0102] Example 7

[0103] Weight loss soft capsules containing L-carnitine, tea polyphenols, and conjugated linoleic acid are prepared from capsule contents and a gel, as follows:

[0104] (1) Preparation of adhesive solution: 300g water, 120g glycerin and 6g black iron oxide-phospholipid composite powder are stirred and heated to 80℃ in a gelling tank. 300g gelatin is added and stirred at 200r / min for 12min. Vacuum is applied for about 30min until there are no bubbles in the adhesive solution. The adhesive solution is passed through a 100-mesh sieve. The solution is allowed to stand for 24h and kept at 60℃ to obtain the adhesive solution.

[0105] (2) Preparation of capsule contents: Mix 340g of L-carnitine, 100g of tea polyphenols and 60g of xylooligosaccharide through a 100-mesh sieve and set aside; heat 100g of conjugated linoleic acid to 70℃, add 40g of beeswax to melt, add 420g of conjugated linoleic acid and stir, add the prepared mixture powder, stir and mix for 20min, pass through a colloid mill twice, and after degassing, the capsule contents are obtained;

[0106] (3) Capsule pressing: The contents of the capsule and the gel are pressed into soft capsules in a soft capsule machine with a filling amount of 0.5g / capsule; the pressed soft capsules are placed in a rotating drum and set at a temperature of 24℃ for 4 hours.

[0107] (4) Drying: Place the prepared soft capsules in a drying tray and dry them at 25°C for 18 hours;

[0108] (5) Selecting capsules: After drying, the soft capsules are inspected on a light inspection table to remove unqualified soft capsules such as irregularly shaped capsules, bubble capsules, capsules of different sizes, and capsules with oil leakage;

[0109] (6) Inner packaging, outer packaging and warehousing: Take qualified soft capsules, bottle them, then package the product according to the packaging requirements, affix labels, and then pack them in cartons. Once they pass the inspection, they are considered finished products. Finally, the finished products should be placed in a cool and dry warehouse.

[0110] The preparation of the black iron oxide-phospholipid composite powder is as follows:

[0111] Add 8g of soybean lecithin and 8g of caprylic / capric glyceride to 45g of water and stir at 1000r / min for 30min at room temperature. Add 10g of black iron oxide and premix at 200r / min for 5min. Then increase the speed to 500r / min and heat to 60℃ and stir for 30min. Add 10g of glycerol and grind 4 times with the colloid mill gap adjusted to 15μm. Dry at 20KPa and 45℃ for 3h to obtain the final product.

[0112] Example 8

[0113] Weight loss soft capsules containing L-carnitine, tea polyphenols, and conjugated linoleic acid are prepared from capsule contents and a gel, as follows:

[0114] (1) Preparation of adhesive solution: 300g water, 120g glycerin and 6g black iron oxide-phospholipid composite powder are stirred and heated to 80℃ in a gelling tank. 300g gelatin is added and stirred at 200r / min for 12min. Vacuum is applied for about 30min until there are no bubbles in the adhesive solution. The adhesive solution is passed through a 100-mesh sieve. The solution is allowed to stand for 24h and kept at 60℃ to obtain the adhesive solution.

[0115] (2) Preparation of capsule contents: 340g of L-carnitine, 100g of tea polyphenols and 60g of galactooligosaccharides were mixed through a 100-mesh sieve and set aside; 100g of conjugated linoleic acid was heated to 70℃, 40g of beeswax was added to melt it, 420g of conjugated linoleic acid was added and stirred, the prepared mixture powder was added, and the mixture was stirred and mixed for 20min. After passing through a colloid mill twice and degassed, the capsule contents were obtained.

[0116] (3) Capsule pressing: The contents of the capsule and the gel are pressed into soft capsules in a soft capsule machine with a filling amount of 0.5g / capsule; the pressed soft capsules are placed in a rotating drum and set at a temperature of 24℃ for 4 hours.

[0117] (4) Drying: Place the prepared soft capsules in a drying tray and dry them at 25°C for 18 hours;

[0118] (5) Selecting capsules: After drying, the soft capsules are inspected on a light inspection table to remove unqualified soft capsules such as irregularly shaped capsules, bubble capsules, capsules of different sizes, and capsules with oil leakage;

[0119] (6) Inner packaging, outer packaging and warehousing: Take qualified soft capsules, bottle them, then package the product according to the packaging requirements, affix labels, and then pack them in cartons. Once they pass the inspection, they are considered finished products. Finally, the finished products should be placed in a cool and dry warehouse.

[0120] The preparation of the black iron oxide-phospholipid composite powder is as follows:

[0121] Add 8g of soybean lecithin and 8g of caprylic / capric glyceride to 45g of water and stir at 1000r / min for 30min at room temperature. Add 10g of black iron oxide and premix at 200r / min for 5min. Then increase the speed to 500r / min and heat to 60℃ and stir for 30min. Add 10g of glycerol and grind 4 times with the colloid mill gap adjusted to 15μm. Dry at 20KPa and 45℃ for 3h to obtain the final product.

[0122] Example 9

[0123] Weight loss soft capsules containing L-carnitine, tea polyphenols, and conjugated linoleic acid are prepared from capsule contents and a gel, as follows:

[0124] (1) Preparation of adhesive solution: 300g water, 120g glycerin and 6g black iron oxide-phospholipid composite powder are stirred and heated to 80℃ in a gelling tank. 300g gelatin is added and stirred at 200r / min for 12min. Vacuum is applied for about 30min until there are no bubbles in the adhesive solution. The adhesive solution is passed through a 100-mesh sieve. The solution is allowed to stand for 24h and kept at 60℃ to obtain the adhesive solution.

[0125] (2) Preparation of capsule contents: 340g of L-carnitine, 100g of tea polyphenols, 30g of galactooligosaccharides and 30g of xylooligosaccharides were mixed through a 100-mesh sieve and set aside; 100g of conjugated linoleic acid was heated to 70℃, 40g of beeswax was added to melt it, 420g of conjugated linoleic acid was added and stirred, the prepared mixture powder was added, and the mixture was stirred and mixed for 20min. After passing through a colloid mill twice and degassed, the capsule contents were obtained.

[0126] (3) Capsule pressing: The contents of the capsule and the gel are pressed into soft capsules in a soft capsule machine with a filling amount of 0.5g / capsule; the pressed soft capsules are placed in a rotating drum and set at a temperature of 24℃ for 4 hours.

[0127] (4) Drying: Place the prepared soft capsules in a drying tray and dry them at 25°C for 18 hours;

[0128] (5) Selecting capsules: After drying, the soft capsules are inspected on a light inspection table to remove unqualified soft capsules such as irregularly shaped capsules, bubble capsules, capsules of different sizes, and capsules with oil leakage;

[0129] (6) Inner packaging, outer packaging and warehousing: Take qualified soft capsules, bottle them, then package the product according to the packaging requirements, affix labels, and then pack them in cartons. Once they pass the inspection, they are considered finished products. Finally, the finished products should be placed in a cool and dry warehouse.

[0130] The preparation of the black iron oxide-phospholipid composite powder is as follows:

[0131] Add 8g of soybean lecithin and 8g of caprylic / capric glyceride to 45g of water and stir at 1000r / min for 30min at room temperature. Add 10g of black iron oxide and premix at 200r / min for 5min. Then increase the speed to 500r / min and heat to 60℃ and stir for 30min. Add 10g of glycerol and grind 4 times with the colloid mill gap adjusted to 15μm. Dry at 20KPa and 45℃ for 3h to obtain the final product.

[0132] Example 10

[0133] Weight loss soft capsules containing L-carnitine, tea polyphenols, and conjugated linoleic acid are prepared from capsule contents and a gel, as follows:

[0134] (1) Preparation of adhesive solution: 300g water, 120g glycerin and 6g black iron oxide-phospholipid composite powder are stirred and heated to 80℃ in a gelling tank. 300g gelatin is added and stirred at 200r / min for 12min. Vacuum is applied for about 30min until there are no bubbles in the adhesive solution. The adhesive solution is passed through a 100-mesh sieve. The solution is allowed to stand for 24h and kept at 60℃ to obtain the adhesive solution.

[0135] (2) Preparation of capsule contents: 340g of L-carnitine, 100g of tea polyphenols, 30g of galactooligosaccharides and 30g of xylooligosaccharides were mixed through a 100-mesh sieve and set aside; 100g of conjugated linoleic acid was heated to 70℃, 40g of beeswax was added to melt it, 420g of conjugated linoleic acid was added and stirred, the prepared mixture powder was added, and the mixture was stirred and mixed for 20min. After passing through a colloid mill twice and degassed, the capsule contents were obtained.

[0136] (3) Capsule pressing: The contents of the capsule and the gel are pressed into soft capsules in a soft capsule machine with a filling amount of 0.5g / capsule; the pressed soft capsules are placed in a rotating drum and set at a temperature of 24℃ for 4 hours.

[0137] (4) Drying: Place the prepared soft capsules in a drying tray and dry them at 25°C for 18 hours;

[0138] (5) Selecting capsules: After drying, the soft capsules are inspected on a light inspection table to remove unqualified soft capsules such as irregularly shaped capsules, bubble capsules, capsules of different sizes, and capsules with oil leakage;

[0139] (6) Inner packaging, outer packaging and warehousing: Take qualified soft capsules, bottle them, then package the product according to the packaging requirements, affix labels, and then pack them in cartons. Once they pass the inspection, they are considered finished products. Finally, the finished products should be placed in a cool and dry warehouse.

[0140] The preparation of the black iron oxide-phospholipid composite powder is as follows:

[0141] 8g soybean lecithin, 8g caprylic / capric triglyceride, and 4g ceramide-3 were added to 45g water and stirred at 1000r / min for 30min at room temperature. 10g black iron oxide was added, and the mixture was premixed at 200r / min for 5min, then the speed was increased to 500r / min and the temperature was raised to 60℃, and stirred for 30min. 10g glycerol was added, and the colloid mill gap was adjusted to 15μm and the mixture was ground 4 times. The mixture was dried at 20KPa and 45℃ for 3h to obtain black iron oxide-phospholipid composite powder.

[0142] Test Example 1

[0143] Dispersion test

[0144] Gel solution: Take 50 mL of the gel solutions prepared in Examples 1-5 and 9-10 and place them in a transparent graduated cylinder. Let them stand at room temperature for 24 h, record the bottom settling layer height (H) and the initial height (H0), and calculate the settling ratio. The formula is as follows:

[0145] Settlement ratio (%) = (H / H0 × 100%).

[0146] Table 1 Settlement ratio results

[0147] Settlement ratio / % Example 1 10.5 Example 2 6.7 Example 3 4.3 Example 4 4.9 Example 5 3.2 Example 9 3.1 Example 10 2.5

[0148] The sedimentation ratio is the ratio of the volume of particulate matter that settles after standing in a colloid to its initial volume. The smaller the value, the better the particle dispersion, the higher the system stability, and the less likely it is to separate into layers.

[0149] Compared to Example 1, the gel solutions in Examples 2-5 all contain soybean lecithin, and the sedimentation ratio results are lower. This may be because its hydrophobic coating effect effectively inhibits the aggregation of black iron oxide particles. Through colloid milling and glycerol-assisted dispersion, a uniform and stable colloidal system is formed.

[0150] Furthermore, in Example 2, the single phospholipid system, through its amphiphilic structure, coats the black iron oxide particles. While acting alone, it exhibits a high adsorption interfacial energy, but some aggregation still occurs. In Example 3, the hydrophobic end of glyceryl monostearate adsorbs onto the particle surface, synergistically forming a multilayered physical barrier with the phospholipids. In Example 4, the added glyceryl hexanoate has weaker steric hindrance due to its short-chain molecules, and its short-chain fatty acid properties lead to a decrease in system viscosity.

[0151] In Examples 5 and 9, the medium-chain triglyceride structure of caprylic / capric triglyceride exhibits low viscosity. Combined with phospholipids, it reduces the interfacial energy of the black iron oxide particles, decreasing agglomeration caused by van der Waals forces. Simultaneously, its strong interfacial activity binds with phospholipids to form a dense coating layer, allowing short-chain fatty acids to penetrate the interparticle gaps, thereby improving the dispersion stability of the adhesive. Building upon this, in Example 10, the long alkyl chain of ceramide-3 in the adhesive is embedded in the microcracks on the surface of the black iron oxide particles, forming a molecular-level anchoring layer through hydrophobic interactions. This layer, in turn, synergistically enhances the double-layer thickness with caprylic / capric triglyceride, reducing particle agglomeration.

[0152] Test Example 2

[0153] Capsule contents: The contents of 5g soft capsules prepared in Examples 1 and 6-9 were opened and dispersed in 50g glycerol. Particle aggregation was observed under a 400x optical microscope, and the proportion of aggregates in the field of view was recorded. Acceptance criteria: Aggregate proportion ≤ 10%. Results are shown in Table 2.

[0154] Table 2. Aggregate Ratio Results

[0155] Aggregate ratio / % Example 1 12.7 Example 6 8.6 Example 7 7.9 Example 8 5.7 Example 9 3.1

[0156] Agglomeration ratio reflects the proportion of agglomerates formed by particle aggregation in the total mixture of capsule contents; the smaller the value, the more uniform the particle dispersion and the better the interfacial compatibility.

[0157] Example 1 shows a high agglomeration rate. Relying solely on beeswax, its amphiphilicity is insufficient to completely cover the powder surface, and powder-oil separation may even occur during subsequent storage. The absence of prebiotics leads to increased interfacial tension between hydrophilic powders such as L-carnitine and tea polyphenols and the conjugated linoleic acid and lipid-soluble matrix, making the powder particles prone to agglomeration into micron-sized aggregates due to van der Waals forces.

[0158] In Example 6 of the composite system, the additional fructooligosaccharide has linear fructose chains linked by β-2,1 glycosidic bonds, forming a flexible hydrophilic network in glycerol. When it readily associates with the polyphenolic hydroxyl groups of tea polyphenols via hydrogen bonding, the hydroxyl groups of fructooligosaccharide preferentially form hydrogen bonds, further reducing hydrophobic interactions between L-carnitine crystals and preventing particle aggregation through steric hindrance. In Example 7, the hydroxyl groups of xylooligosaccharide form hydrogen bonds with the carboxyl groups of conjugated linoleic acid, improving water-oil interface compatibility and reducing the probability of aggregation. In Example 8, galactooligosaccharide contains galactose hydroxyl groups and a C6 methyl group, forming an amphiphilic structure of "hydrophilic segments-hydrophobic microdomains" in glycerol. The hydrophilic microdomains interact with the fatty acid chains of conjugated linoleic acid, reducing phase separation between oil and L-carnitine. The hydrophilic segments form multiple hydrogen bonds with the phenolic hydroxyl groups of tea polyphenols, inhibiting particle adhesion caused by the oxidative polymerization of tea polyphenols. Its branched structure forms a three-dimensional network in glycerol, anchoring L-carnitine crystals at network nodes and preventing free aggregation.

[0159] Example 9 uses a combination of xylooligosaccharides and galactooligosaccharides. Xylooligosaccharides preferentially adsorb onto the surface of L-carnitine to form a charge barrier, while galactooligosaccharides form an emulsion layer at the interface of tea polyphenols and conjugated linoleic acid. The two are cross-linked by hydrogen bonds to form a stable ternary system of "particles-prebiotics-oils", which reduces the aggregation ratio and improves the stability of the capsule contents.

[0160] Test Example 3

[0161] Stability test

[0162] High temperature test: The soft capsules of Examples 1-5 and Examples 9-10 were placed in an open container and placed at 60°C for 10 days. The appearance was observed and recorded.

[0163] High humidity test: The soft capsules were exposed at 25°C and 75% RH for 10 days. The appearance of the soft capsules and the dissolution rate of the contents were observed and recorded. The results are shown in Table 3.

[0164] Table 3 Stability Test Results

[0165] Appearance Moisture absorption rate / % Example 1 Light Microsoft 9.7 Example 2 No significant changes 6.2 Example 3 No significant changes 5.4 Example 4 No significant changes 4.8 Example 5 No significant changes 2.3 Example 9 No significant changes 1.5 Example 10 No significant changes 1.2

[0166] Example 1: At high temperatures, slight softening occurred, and moisture easily penetrated the capsule material into the contents, causing the gelatin to absorb water and swell. Furthermore, the thermal oxidation polymerization of conjugated linoleic acid in the contents resulted in polymer molecules that interacted with the capsule material, further affecting the stability of the soft capsule. Examples 2-5: Under high-temperature conditions, the presence of a phospholipid complex system may have inhibited the softening of the capsule material. Phospholipid molecules in soybean phospholipids can form a hydrophobic network in the gelatin matrix, synergistically enhancing the thermal stability of the capsule material with beeswax and preventing the increased fluidity caused by the high-temperature oxidation of conjugated linoleic acid and other oil components. It can also form a rigid framework, delaying the thermal movement of gelatin segments at high temperatures, thereby affecting the overall stability of the soft capsule.

[0167] Furthermore, in Example 5, the phospholipid coating layer can prevent black iron oxide from directly contacting moisture / oxygen in the environment; in Example 9, the combination of galactooligosaccharides and xylooligosaccharides binds to free water through hydrogen bonds, reducing the water activity of the contents, inhibiting the penetration of external moisture into the soft capsule, reducing hygroscopicity and oxidation risk, and extending the storage stability of the soft capsule; in Example 10, ceramide-3 is additionally added, whose amphiphilic structure can synergistically form a dense coating layer with phospholipids, improving the overall structural stability.

[0168] Test Example 4

[0169] Microbiological indicators

[0170] Total bacterial count test: The test was conducted in accordance with GB4789.2-2016 "Food Microbiology Examination - Total Bacterial Count".

[0171] Coliform bacteria detection: The determination was carried out in accordance with GB4789.3-2010 "Food Microbiology Examination - Coliform Bacterial Count".

[0172] Physicochemical indicators

[0173] L-carnitine: In accordance with the provisions of GB1903.13 "National Food Safety Standard for Food Fortifiers L-carnitine (L-carnitine)".

[0174] Tea polyphenols: should comply with the provisions of GB1886.211 "National Food Safety Standard for Food Additives Tea Polyphenols (also known as Vitamin Polyphenols)".

[0175] Gelatin, purified water, glycerin, beeswax, and black iron oxide all comply with the provisions of the Pharmacopoeia of the People's Republic of China (2010 edition, Part II).

[0176] Sensory evaluation

[0177] Observe the appearance of the capsules and the color of the contents; there should be no visible foreign impurities. The odor should have the inherent taste of the product and be free of any off-odors. Record the results. See Table 4.

[0178] Table 4. Results of Microbiological and Physicochemical Indicators Detection and Sensory Evaluation

[0179]

[0180]

[0181] Examples 1-10 also comply with the provisions of the "Food Safety Law of the People's Republic of China" and the "Administrative Measures for Food Registration and Filing".

[0182] Test Example 5

[0183] Synergistic fat reduction effect test

[0184] Thirty volunteers were selected for the study, aged 25-40 years, including 13 men and 17 women. All participants had no history of smoking, no cardiopulmonary or skeletal muscle diseases, and no symptoms or signs of myocardial ischemia during exercise testing (exercise ECG showed ST segment depression within 1 mm), and no secondary obesity caused by other reasons.

[0185] In a double-blind study, participants were instructed to maintain a relatively unchanged lifestyle throughout the testing period, including dietary habits, exercise, and other daily activities, and not to take any other medications or supplements. The test group consisted of five groups of five participants each, who took two soft capsules prepared according to Examples 6-10 of this invention three times daily with warm water for three consecutive weeks. Individual comparisons were made before and after the test, measuring aerobic exercise capacity and blood lactate levels during the recovery period. The control group consisted of five participants who received an equal weight of distilled water in white paper cups. The results are shown in Table 5.

[0186] Table 5. Changes in blood lactate and respiratory quotient before and after exercise in volunteers 3 minutes after exercise.

[0187]

[0188]

[0189] The respiratory quotient (RQ) reflects the type of energy metabolism substrate. When L-carnitine acts as a carrier to promote the entry of long-chain fatty acids into the mitochondria, it accelerates β-oxidation for energy and reduces dependence on carbohydrates. A decrease in the RQ indicates high fat utilization.

[0190] Blood lactate reflects the intensity of anaerobic metabolism and the degree of fatigue after exercise. When L-carnitine enhances mitochondrial function, it enters the tricarboxylic acid cycle to provide energy and promotes the oxidation of lactate to pyruvate, it can reduce lactate accumulation. When the blood lactate level is low, it means that lactate is cleared quickly and exercise tolerance is improved.

[0191] After continuous use of the soft capsules prepared in Examples 6-10, the volunteers participating in the test showed a decrease in blood lactate levels and respiratory quotient, indicating that the soft capsules have a certain synergistic fat reduction effect and can improve the subjects' aerobic exercise capacity and blood lactate levels during the recovery period.

[0192] Examples 6-10 show that soft capsules combined with prebiotics can accelerate the entry of long-chain fatty acids into mitochondria, promote fat energy supply, and reduce carbohydrate dependence, which is consistent with the results of decreased respiratory quotient. Tea polyphenols reduce fat synthesis by inhibiting fatty acid synthase activity, while activating the AMPK signaling pathway, enhancing mitochondrial function, and optimizing fat metabolism efficiency. L-carnitine can promote the oxidation of lactic acid to pyruvate, accelerating its entry into the tricarboxylic acid cycle for energy supply, thereby reducing blood lactate accumulation and providing an energy basis for continuous fat loss. Conjugated linoleic acid can further enhance fat breakdown by regulating the expression of lipid metabolism genes in this process, forming a triple action pathway of "promoting transport - inhibiting synthesis - accelerating oxidation" with L-carnitine and tea polyphenols.

[0193] In Example 9, the addition of a compound prebiotic includes galactooligosaccharides, which activate β-glucosidase and accelerate the release of tea polyphenol aglycones; xylooligosaccharides promote calcium / iron absorption, enhance mitochondrial function, and thus promote the absorption and conversion of L-carnitine. Xylooligosaccharides are acid-resistant and can form a protective layer in the stomach, reducing the degradation of galactooligosaccharides in the upper digestive tract and ensuring that more active ingredients reach the colon.

[0194] Furthermore, in Example 10, ceramide-3 was introduced into the black iron oxide-phospholipid composite powder based on Example 9. This effectively enhances the micromicelle encapsulation efficiency of fat-soluble components such as conjugated linoleic acid and tea polyphenols in the intestine, improving bioavailability and simultaneously enhancing their dispersion and sustained-release properties within the capsule contents. This invention's multi-component synergy not only increases the proportion of energy supplied by fat but also optimizes the body's metabolic state by improving mitochondrial function and lactic acid clearance efficiency, providing a more efficient energy metabolism mode for fat reduction.

Claims

1. Weight loss L-carnitine, tea polyphenols, and conjugated linoleic acid soft capsules, prepared from capsule contents and a gel, characterized in that... The capsule contents are composed of the following ingredients in parts by weight: 30-50 parts L-carnitine, 5-20 parts tea polyphenols, 45-60 parts conjugated linoleic acid, 2-6 parts beeswax, and 2-10 parts prebiotics; the gel is composed of the following ingredients in parts by weight: 20-50 parts gelatin, 10-20 parts glycerin, 20-50 parts water, and 0.5-1 part stabilizer. The stabilizer is prepared as follows: Add 0.1-2 parts soybean lecithin and 0.1-2 parts functional additives to 3-8 parts water and stir at 800-1000 r / min for 20-50 min at room temperature; add 0.5-3 parts black iron oxide, premix at 100-200 r / min for 3-5 min, then increase the speed to 300-800 r / min and heat to 50-80℃, stir for 10-30 min; add 0.5-3 parts glycerol, adjust the colloid mill gap to 15 μm and grind 4 times; vacuum dry for 1-5 h to obtain the final product.

2. The weight-loss L-carnitine tea polyphenol conjugated linoleic acid soft capsule according to claim 1, characterized in that, The functional additive is at least one of glyceryl monostearate, glyceryl hexanoate, glyceryl caprylate, and ceramide-3.

3. The weight-loss L-carnitine tea polyphenol conjugated linoleic acid soft capsule according to claim 1, characterized in that, The functional additive is a mixture of caprylic / capric triglyceride and ceramide-3.

4. The weight-loss L-carnitine tea polyphenol conjugated linoleic acid soft capsule according to claim 1, characterized in that, The prebiotic is at least one of fructooligosaccharides, xylooligosaccharides, and galactooligosaccharides.

5. The weight-loss L-carnitine tea polyphenol conjugated linoleic acid soft capsule according to claim 1, characterized in that, The prebiotic is a mixture of xylooligosaccharides and galactooligosaccharides.

6. The weight-loss L-carnitine tea polyphenol conjugated linoleic acid soft capsule according to claim 1, characterized in that, The vacuum drying for 1-5 hours refers to drying at 20 kPa and 45°C for 1-5 hours.

7. A method for preparing the weight-loss L-carnitine tea polyphenol conjugated linoleic acid soft capsules according to any one of claims 1-6, characterized in that, Includes the following steps: (1) Preparation of adhesive solution: Stir and heat 10-20 parts of glycerin, 20-50 parts of water and 0.5-1 parts of stabilizer in a dissolving tank to 70-80°C, add 20-50 parts of gelatin and stir until the gelatin is completely dissolved; vacuum the adhesive solution mixture for 20-30 minutes, sieve and let stand to obtain the adhesive solution; (2) Preparation of capsule contents: Mix 30-50 parts of L-carnitine, 5-20 parts of tea polyphenols and 2-10 parts of prebiotics through a 100-mesh sieve and set aside; heat 5-15 parts of conjugated linoleic acid to 50-80℃, add 2-6 parts of beeswax to melt, add the remaining conjugated linoleic acid and stir, add the mixed powder, stir and mix for 10-30 minutes, pass through a colloid mill 1-3 times, and after degassing, the capsule contents are obtained. (3) Press the capsule contents and gel into soft capsules in a soft capsule machine and shape them; (4) Washing the pills: Wash the pills with 95% edible ethanol; (5) Drying: Place the prepared soft capsules in a drying tray and dry them at a temperature of 20-26℃ for 18-20 hours; (6) Selecting capsules: After drying, the soft capsules are inspected on a light inspection table to remove unqualified soft capsules such as irregularly shaped capsules, bubble capsules, capsules of different sizes, and capsules with oil leakage; (7) Inner packaging, outer packaging and warehousing: Take qualified soft capsules, bottle them, then package the product according to the packaging requirements, affix labels, and then pack them in cartons. Once they pass the inspection, they are considered finished products. Finally, the finished products should be placed in a cool and dry warehouse.

8. The preparation method of the weight-loss L-carnitine tea polyphenol conjugated linoleic acid soft capsules according to claim 7, characterized in that, The sieving and heat preservation operation involves passing the obtained adhesive solution through a 100-mesh sieve; letting it stand for 24 hours; and maintaining the temperature at 50-60℃.

9. The preparation method of the weight-loss L-carnitine tea polyphenol conjugated linoleic acid soft capsules according to claim 7, characterized in that, The compression and shaping process involves placing the compressed soft capsules in a rotating drum and shaping them for 4 hours at a temperature of 18-24℃.

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