Quick-acting red-removing repairing product and method thereof
By utilizing the synergistic effect of ingredients encapsulated in nano-microcapsules and liposomes, a fast-acting redness-reducing and repairing product was prepared, solving the problems of short-lived effects and irritation of existing redness-reducing and repairing products, and achieving long-lasting redness reduction and barrier repair effects on sensitive skin.
Patent Information
- Application Number
- CN202511055787.6
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-07-30
- Publication Date
- 2025-10-31
- Estimated Expiration
- Not applicable · inactive patent
AI Technical Summary
Existing redness-reducing and repairing products mostly alleviate skin inflammation from a single aspect, resulting in short-term effects and potential skin irritation. They cannot effectively address the problems of impaired skin barrier function and aggravated inflammatory responses in sensitive skin.
This product utilizes ingredients such as caprylic/capric triglycerides, phosphatidylcholine, eicosapentaenoic acid, docosahexaenoic acid, turmeric rhizome extract, and centella asiatica extract, encapsulated in nano-microcapsules and combined with the synergistic effect of curcumin and asiaticoside to prepare a fast-acting redness-reducing and repairing product. It achieves a sustained-release effect by regulating the skin's immune system and strengthening its barrier function.
It effectively inhibits skin inflammation, promotes skin barrier reconstruction, reduces skin redness and swelling, prolongs the action time of active ingredients in the skin, is suitable for sensitive skin, and has a good repair effect.
Smart Images

Figure CN120859910A_ABST
Abstract
Description
Technical Field
[0001] This invention belongs to the field of skincare technology, specifically a product and method for fast-acting redness reduction and repair. Background Technology
[0002] Sensitive skin affects 60-70% of women and 50-60% of men worldwide. As a global market, the sensitive skin market has continued to expand in recent years as consumers pay increasing attention to skin health and safety.
[0003] Redness and inflammation are the main causes of sensitive skin. The primary causes of redness and inflammation are: 1. Impaired skin barrier function: Low moisture content in the stratum corneum, high transepidermal water loss (TEWL), abnormal physiological processes such as peeling and metabolism, loss of intercellular lipids and sebum film components, increased permeability of the stratum corneum, making it easier for external substances to invade and cause irritation. Main manifestations: dry, thin, brittle, peeling skin, and high TEWL index; 2. Exacerbated inflammatory response (immune response): The penetration of external irritants aggravates the inflammatory response, releases various inflammatory mediators, and initiates a cascade of inflammatory responses, including IL-1 and IL-1. Inflammatory factors such as L-8, TNF-0, and PGE2 are involved, mainly manifested as skin inflammation, redness, and swelling. Thirdly, there is hyperresponsiveness of nerve endings: after tissue damage and inflammation, inflammatory agents are released, primary sensory neurons are activated, and peptides and neurotransmitters (PAR-2, CGRP, SP) are released, triggering skin sensitivity and neurogenic inflammation, mainly manifested as itching, stinging, and discomfort. Currently, most products on the market only alleviate skin inflammation and redness from a single aspect, and their effectiveness is short-lived. Some products even cause greater irritation to the skin, therefore, improvements are needed. Summary of the Invention
[0004] The purpose of this invention is to provide a fast-acting redness-reducing and repairing product and method thereof to solve the problems mentioned in the background art.
[0005] To achieve the above objectives, the present invention provides the following technical solution: a fast-acting redness-reducing and repairing product, comprising the following ingredients: water, caprylic / capric triglyceride, glycerin, sorbitol, phosphatidylcholine, 1,3-propanediol, xanthan gum, eicosapentaenoic acid, docosahexaenoic acid, phytosphingosine, centella asiatica extract, tocopheryl acetate, turmeric rhizome extract, and 1,2-hexanediol.
[0006] As a preferred embodiment of the present invention, the main component of the Centella asiatica extract is asiaticoside, which is a triterpenoid saponin compound extracted from the aerial parts of Centella asiatica, a plant of the Apiaceae family.
[0007] As a preferred embodiment of the present invention, the main component of the turmeric rhizome extract is curcumin, which is a polyphenolic compound extracted from the rhizome of the ginger family plant turmeric.
[0008] As a preferred embodiment of the present invention, the eicosapentaenoic acid, docosahexaenoic acid, turmeric root extract, phytosphingosine, and centella asiatica extract are encapsulated in nano-microcapsule liposomes.
[0009] To achieve the aforementioned other objective, the present invention provides the following technical solution: a method for preparing a fast-acting redness-reducing and repairing product, wherein the preparation method is applicable to the aforementioned fast-acting redness-reducing and repairing product, and the preparation process comprises the following steps:
[0010] Step 1: Raw material processing
[0011] Grinding solid raw materials: Place solid raw materials such as xanthan gum into a mortar and grind them slowly with a pestle until the raw material particles are small enough to pass through a 100-200 mesh sieve. After grinding, collect the ground raw materials in a clean storage container and seal them for preservation.
[0012] Liquid raw material filtration: Pour the liquid raw materials such as caprylic / capric triglyceride and 1,3-propanediol into a graduated cylinder, and then filter them using a 0.45μm filter membrane. After filtration, pour the filtered liquid raw materials into a beaker and seal it for storage.
[0013] Step 2: Preparation of nanocapsule liposomes
[0014] Accurately weigh appropriate amounts of caprylic / capric triglyceride, phosphatidylcholine, and tocopheryl acetate using an electronic balance. Then pour them into a stirrer equipped with a heater and stir. Set the temperature of the stirrer to 65-70℃ and the speed to 300-400 rpm. Then turn on the stirrer and stir for 15-20 minutes until the phosphatidylcholine is completely dissolved in the caprylic / capric triglyceride and the solution becomes clear and homogeneous. Then stop stirring to obtain the lipid phase.
[0015] Accurately measure an appropriate amount of water using a graduated cylinder and pour it into another clean beaker. Then, add 1,3-propanediol and 1,2-hexanediol in sequence. Next, use a glass rod to stir the solution in the beaker until homogeneous. Then, slowly add eicosapentaenoic acid, docosahexaenoic acid, turmeric root extract, phytosphingosine, and centella asiatica extract while stirring continuously. Immediately afterward, place the beaker in a water bath and set the temperature to 45-50℃. Stir at 200-300 rpm for 30-40 minutes to obtain the aqueous phase.
[0016] Use a dropper to slowly add the aqueous phase to the lipid phase at a rate of 1-2 drops per second, while stirring at 800-1000 rpm to ensure that the lipid and aqueous phases can fully contact and mix. After the addition is complete, continue stirring for 15-20 minutes to obtain a crude emulsion.
[0017] The crude emulsion was transferred to a high-pressure homogenizer. The homogenization pressure was set to 600-700 bar. The homogenizer was turned on for the first homogenization, which took 3-5 minutes. After the first homogenization was completed, the resulting primary emulsion was removed and allowed to stand for 5-10 minutes. Then, the primary emulsion was poured into the high-pressure homogenizer for the second homogenization. The pressure was set to 500-600 bar and the time was 3-5 minutes. The above homogenization process was repeated 2-3 times to obtain the nanocapsule liposome solution.
[0018] The prepared nanocapsule liposome solution was transferred to a clean storage container using a clean glass rod and sealed and stored at 4°C for 24 hours.
[0019] Step 3: Prepare the main emulsion of the product
[0020] Weigh caprylic / capric triglyceride into a small beaker and place it in a heating mantle. Heat to 65-70℃, stirring constantly during the heating process to ensure that the oil phase is heated evenly.
[0021] Add an appropriate amount of water to the emulsifying pot, then add glycerin, sorbitol and xanthan gum in sequence. Turn on the stirrer and stir at 300-400 rpm. At the same time, place the emulsifying pot in a heating mantle and heat to 75-80℃. After 20-30 minutes, stop heating and stirring.
[0022] Slowly pour the oil phase into the aqueous phase in the emulsification pot, keeping the stirring speed constant during the pouring process. After pouring, increase the stirring speed to 1000-1200 rpm and continue stirring for 10-15 minutes. When the emulsion becomes milky white and delicate, and there are no obvious oil droplets floating, the initial emulsification is complete.
[0023] Pour the emulsion obtained after emulsification into a homogenizer, set the pressure to 400-500 bar, and homogenize the emulsion 2-3 times, each time for 3-5 minutes. When the emulsion particles are fine, uniform and free of particles, stop homogenizing to obtain the main product emulsion.
[0024] Step 4: Mixing
[0025] The nanocapsule liposome solution obtained in step two is slowly added to the main product emulsion prepared in step three, while stirring at 600-800 rpm for 20-25 minutes to ensure that the nanocapsule liposomes can be uniformly dispersed in the emulsion, thereby obtaining the desired product.
[0026] Step 5: Adjust the pH value
[0027] Use a pH meter to measure the pH value of the product. If the pH value is not within the required range, adjust the pH value slowly with 0.1 mol / L citric acid solution or sodium hydroxide solution according to the measurement results. After stirring thoroughly, let it stand for 5-10 minutes to allow the pH value to stabilize before making the next measurement and adjustment until the pH value meets the requirements.
[0028] Step Six: Filtering
[0029] The product with the adjusted pH value is filtered through a 0.22μm microporous membrane to remove any small particles and impurities.
[0030] Step 7: Filling
[0031] The filtered product is then filled into clean packaging containers using a filling machine.
[0032] As a preferred embodiment of the present invention, the balance pan in step two should be wiped with a clean paper towel after each weighing.
[0033] As a preferred technical solution of the present invention, when using a glass rod for stirring in step two, care should be taken to ensure that the glass rod does not touch the wall or bottom of the beaker.
[0034] As a preferred embodiment of the present invention, after each homogenization by the homogenizer in step two, the emulsion needs to be taken and the particle size distribution needs to be detected by a particle size analyzer.
[0035] As a preferred embodiment of the present invention, the pH value of the product in step five is required to be between 5.5 and 6.0.
[0036] The beneficial effects of this invention are as follows:
[0037] This invention utilizes the synergistic effect of turmeric root extract and centella asiatica extract to enhance skin immune regulation and skin barrier function. On one hand, it can inhibit skin inflammatory responses, effectively reduce inflammation, and inhibit microbial growth. On the other hand, it can promote skin barrier reconstruction, promote wound healing, and protect the ECM matrix, making it particularly suitable for allergic and specific skin types. Furthermore, by encapsulating eicosapentaenoic acid, docosahexaenoic acid, turmeric root extract, phytosphingosine, and centella asiatica extract in nano-microcapsules liposomes, the activity of the product can be ensured, achieving a gradual and sustained-release effect. This allows the active ingredients to be slowly released into the skin, prolonging their duration of action. Attached Figure Description
[0038] Figure 1 This is a flowchart of the preparation method of the present invention. Detailed Implementation
[0039] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.
[0040] like Figure 1 As shown, this embodiment of the invention provides a fast-acting redness-reducing and repairing product, comprising the following ingredients: water, caprylic / capric triglyceride, glycerin, sorbitol, phosphatidylcholine, 1,3-propanediol, xanthan gum, eicosapentaenoic acid, docosahexaenoic acid, phytosphingosine, centella asiatica extract, tocopheryl acetate, turmeric rhizome extract, and 1,2-hexanediol.
[0041] The fast-acting redness-reducing and repairing product composed of the above ingredients works by regulating the skin's immune system and strengthening the skin barrier function. It immediately and quickly reduces symptoms of redness, swelling, and inflammation, while also treating chronic redness. It has a good repairing effect on allergic skin and specific skin types.
[0042] The main component of Centella asiatica extract is asiaticoside, which is a triterpenoid saponin compound extracted from the aerial parts of Centella asiatica, a plant of the Apiaceae family.
[0043] asiaticoside can promote the secretion of more keratin and lipid components by keratinocytes, strengthen the integrity of the skin barrier, and reduce moisture loss and invasion of external stimuli; it can stimulate fibroblasts to secrete more collagen, thereby repairing the damaged ECM matrix; it can also promote the production of collagen and elastin fibers, improve skin elasticity and firmness, promote wound healing, reduce scar formation, and benefit skin barrier repair and regeneration; in addition, asiaticoside can inhibit the release of inflammatory mediators (IL-1, MMP-1), reduce inflammatory response, and relieve skin inflammation.
[0044] The main component of turmeric rhizome extract is curcumin, a polyphenolic compound extracted from the rhizome of turmeric, a plant in the ginger family.
[0045] Curcumin can inhibit PGES-1 and reduce the synthesis of PGE2, thereby effectively inhibiting the inflammatory response. At the same time, curcumin can also regulate the p38 MAPK signaling pathway, inhibit the in vitro induction of interleukin 1β, and reduce the secretion level of COX-2, thereby achieving effective anti-inflammatory effects.
[0046] Among them, eicosapentaenoic acid, docosahexaenoic acid, turmeric root extract, phytosphingosine, and centella asiatica extract are encapsulated in nano-microcapsule liposomes.
[0047] Because eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are unsaturated fatty acids with multiple double bonds in their molecules, they are easily oxidized, leading to product spoilage, off-odors, and loss of biological activity. Curcumin in turmeric root extract also has strong oxidizing properties and is easily decomposed under conditions such as light, heat, and oxygen. Therefore, using nano-microcapsule liposomes can encapsulate these active ingredients, forming a protective barrier that reduces their contact with the external environment, thereby effectively preventing oxidation reactions and extending the product's shelf life. In addition, nano-microcapsule liposomes have a small particle size, which allows them to better penetrate the stratum corneum of the skin, slowly releasing the active ingredients into the skin and prolonging their duration of action.
[0048] like Figure 1 As shown, this embodiment of the invention also provides a method for preparing a fast-acting redness-reducing and repairing product. The preparation method is applicable to the above-mentioned fast-acting redness-reducing and repairing product, and its preparation process includes the following steps:
[0049] Step 1: Raw material processing
[0050] Grinding solid raw materials: Place solid raw materials such as xanthan gum into a mortar and grind them slowly with a pestle until the raw material particles are small enough to pass through a 100-200 mesh sieve. After grinding, collect the ground raw materials in a clean storage container and seal them for preservation.
[0051] Liquid raw material filtration: Pour the liquid raw materials such as caprylic / capric triglyceride and 1,3-propanediol into a graduated cylinder, and then filter them using a 0.45μm filter membrane. After filtration, pour the filtered liquid raw materials into a beaker and seal it for storage.
[0052] Step 2: Preparation of nanocapsule liposomes
[0053] Accurately weigh appropriate amounts of caprylic / capric triglyceride, phosphatidylcholine, and tocopheryl acetate using an electronic balance. Then pour them into a stirrer equipped with a heater and stir. Set the temperature of the stirrer to 65-70℃ and the speed to 300-400 rpm. Then turn on the stirrer and stir for 15-20 minutes until the phosphatidylcholine is completely dissolved in the caprylic / capric triglyceride and the solution becomes clear and homogeneous. Then stop stirring to obtain the lipid phase.
[0054] Accurately measure an appropriate amount of water using a graduated cylinder and pour it into another clean beaker. Then, add 1,3-propanediol and 1,2-hexanediol in sequence. Next, use a glass rod to stir the solution in the beaker until homogeneous. Then, slowly add eicosapentaenoic acid, docosahexaenoic acid, turmeric root extract, phytosphingosine, and centella asiatica extract while stirring continuously. Immediately afterward, place the beaker in a water bath and set the temperature to 45-50℃. Stir at 200-300 rpm for 30-40 minutes to obtain the aqueous phase.
[0055] Use a dropper to slowly add the aqueous phase to the lipid phase at a rate of 1-2 drops per second, while stirring at 800-1000 rpm to ensure that the lipid and aqueous phases can fully contact and mix. After the addition is complete, continue stirring for 15-20 minutes to obtain a crude emulsion.
[0056] The crude emulsion was transferred to a high-pressure homogenizer. The homogenization pressure was set to 600-700 bar. The homogenizer was turned on for the first homogenization, which took 3-5 minutes. After the first homogenization was completed, the resulting primary emulsion was removed and allowed to stand for 5-10 minutes. Then, the primary emulsion was poured into the high-pressure homogenizer for the second homogenization. The pressure was set to 500-600 bar and the time was 3-5 minutes. The above homogenization process was repeated 2-3 times to obtain the nanocapsule liposome solution.
[0057] The prepared nanocapsule liposome solution was transferred to a clean storage container using a clean glass rod and sealed and stored at 4°C for 24 hours.
[0058] Step 3: Prepare the main emulsion of the product
[0059] Weigh caprylic / capric triglyceride into a small beaker and place it in a heating mantle. Heat to 65-70℃, stirring constantly during the heating process to ensure that the oil phase is heated evenly.
[0060] Add an appropriate amount of water to the emulsifying pot, then add glycerin, sorbitol and xanthan gum in sequence. Turn on the stirrer and stir at 300-400 rpm. At the same time, place the emulsifying pot in a heating mantle and heat to 75-80℃. After 20-30 minutes, stop heating and stirring.
[0061] Slowly pour the oil phase into the aqueous phase in the emulsification pot, keeping the stirring speed constant during the pouring process. After pouring, increase the stirring speed to 1000-1200 rpm and continue stirring for 10-15 minutes. When the emulsion becomes milky white and delicate, and there are no obvious oil droplets floating, the initial emulsification is complete.
[0062] Pour the emulsion obtained after emulsification into a homogenizer, set the pressure to 400-500 bar, and homogenize the emulsion 2-3 times, each time for 3-5 minutes. When the emulsion particles are fine, uniform and free of particles, stop homogenizing to obtain the main product emulsion.
[0063] Step 4: Mixing
[0064] The nanocapsule liposome solution obtained in step two is slowly added to the main product emulsion prepared in step three, while stirring at 600-800 rpm for 20-25 minutes to ensure that the nanocapsule liposomes can be uniformly dispersed in the emulsion, thereby obtaining the desired product.
[0065] Step 5: Adjust the pH value
[0066] Use a pH meter to measure the pH value of the product. If the pH value is not within the required range, adjust the pH value slowly with 0.1 mol / L citric acid solution or sodium hydroxide solution according to the measurement results. After stirring thoroughly, let it stand for 5-10 minutes to allow the pH value to stabilize before making the next measurement and adjustment until the pH value meets the requirements.
[0067] Step Six: Filtering
[0068] The product with the adjusted pH value is filtered through a 0.22μm microporous membrane to remove any small particles and impurities.
[0069] Step 7: Filling
[0070] The filtered product is then filled into clean packaging containers using a filling machine.
[0071] The resulting product is a pale yellow viscous solution. The recommended addition level in soothing, repairing, and moisturizing products is 2%. The toxicological properties of the product were evaluated in in vitro and in vivo tests, and the characteristics are as follows: cytotoxicity: none; mutagenicity (Ankle test): none; eye irritation test: none; human patch test: none.
[0072] In step two, the balance pan should be wiped with a clean paper towel after each weighing.
[0073] By wiping the balance pan after each weighing, cross-contamination of raw materials can be avoided.
[0074] In step two, when stirring with a glass rod, be careful not to let the glass rod touch the walls or bottom of the beaker.
[0075] When using a glass rod for stirring, it is important to pay attention to the stirring speed to prevent the formation of air bubbles.
[0076] In step two, after each homogenization, the emulsion needs to be collected and its particle size distribution needs to be detected using a particle size analyzer.
[0077] Homogenization can be stopped when the average particle size of the nanocapsule liposomes is between 100-300 nm and the particle size distribution is uniform (polydispersity index PDI is less than 0.3).
[0078] In step five, the required pH value of the product is between 5.5 and 6.0.
[0079] A pH value of 5.5-6.0 is close to the pH value of human skin, and adjusting the pH value can reduce the irritation of the product to the human body.
[0080] It should be noted that, in this document, relational terms such as "first" and "second" are used only to distinguish one entity or operation from another, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Furthermore, the terms "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such process, method, article, or apparatus.
[0081] Although embodiments of the invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the appended claims and their equivalents.
Claims
1. A product for rapid redness reduction and repair, characterized in that, It includes the following ingredients: water, caprylic / capric triglyceride, glycerin, sorbitol, phosphatidylcholine, 1,3-propanediol, xanthan gum, eicosapentaenoic acid, docosahexaenoic acid, phytosphingosine, centella asiatica extract, tocopheryl acetate, turmeric rhizome extract, and 1,2-hexanediol.
2. The product for rapid redness reduction and repair according to claim 1, characterized in that: The main component of the Centella asiatica extract is asiaticoside, which is a triterpenoid saponin compound extracted from the aerial parts of Centella asiatica, a plant of the Apiaceae family.
3. The product for rapid redness reduction and repair according to claim 1, characterized in that: The main component of the turmeric rhizome extract is curcumin, which is a polyphenolic compound extracted from the rhizome of the ginger plant turmeric.
4. The product for rapid redness reduction and repair according to claim 1, characterized in that: The eicosapentaenoic acid, docosahexaenoic acid, turmeric root extract, phytosphingosine, and centella asiatica extract are encapsulated in nano-microcapsule liposomes.
5. A method for preparing a fast-acting redness-reducing and repairing product, characterized in that: The preparation method is applicable to a fast-acting redness-reducing and repairing product as described in any one of claims 1-4, and its preparation process includes the following steps: Step 1: Raw material processing Grinding solid raw materials: Place solid raw materials such as xanthan gum into a mortar and grind them slowly with a pestle until the raw material particles are small enough to pass through a 100-200 mesh sieve. After grinding, collect the ground raw materials in a clean storage container and seal them for preservation. Liquid raw material filtration: Pour the liquid raw materials such as caprylic / capric triglyceride and 1,3-propanediol into a graduated cylinder, and then filter them using a 0.45μm filter membrane. After filtration, pour the filtered liquid raw materials into a beaker and seal it for storage. Step 2: Preparation of nanocapsule liposomes Accurately weigh appropriate amounts of caprylic / capric triglyceride, phosphatidylcholine, and tocopheryl acetate using an electronic balance. Then pour them into a stirrer equipped with a heater and stir. Set the temperature of the stirrer to 65-70℃ and the speed to 300-400 rpm. Then turn on the stirrer and stir for 15-20 minutes until the phosphatidylcholine is completely dissolved in the caprylic / capric triglyceride and the solution becomes clear and homogeneous. Then stop stirring to obtain the lipid phase. Accurately measure an appropriate amount of water using a graduated cylinder and pour it into another clean beaker. Then, add 1,3-propanediol and 1,2-hexanediol in sequence. Next, use a glass rod to stir the solution in the beaker until homogeneous. Then, slowly add eicosapentaenoic acid, docosahexaenoic acid, turmeric root extract, phytosphingosine, and centella asiatica extract while stirring continuously. Immediately afterward, place the beaker in a water bath and set the temperature to 45-50℃. Stir at 200-300 rpm for 30-40 minutes to obtain the aqueous phase. Use a dropper to slowly add the aqueous phase to the lipid phase at a rate of 1-2 drops per second, while stirring at 800-1000 rpm to ensure that the lipid and aqueous phases can fully contact and mix. After the addition is complete, continue stirring for 15-20 minutes to obtain a crude emulsion. The crude emulsion was transferred to a high-pressure homogenizer. The homogenization pressure was set to 600-700 bar. The homogenizer was turned on for the first homogenization, which took 3-5 minutes. After the first homogenization was completed, the resulting primary emulsion was removed and allowed to stand for 5-10 minutes. Then, the primary emulsion was poured into the high-pressure homogenizer for the second homogenization. The pressure was set to 500-600 bar and the time was 3-5 minutes. The above homogenization process was repeated 2-3 times to obtain the nanocapsule liposome solution. The prepared nanocapsule liposome solution was transferred to a clean storage container using a clean glass rod and sealed and stored at 4°C for 24 hours. Step 3: Prepare the main emulsion of the product Weigh caprylic / capric triglyceride into a small beaker and place it in a heating mantle. Heat to 65-70℃, stirring constantly during the heating process to ensure that the oil phase is heated evenly. Add an appropriate amount of water to the emulsifying pot, then add glycerin, sorbitol and xanthan gum in sequence. Turn on the stirrer and stir at 300-400 rpm. At the same time, place the emulsifying pot in a heating mantle and heat to 75-80℃. After 20-30 minutes, stop heating and stirring. Slowly pour the oil phase into the aqueous phase in the emulsification pot, keeping the stirring speed constant during the pouring process. After pouring, increase the stirring speed to 1000-1200 rpm and continue stirring for 10-15 minutes. When the emulsion becomes milky white and delicate, and there are no obvious oil droplets floating, the initial emulsification is complete. Pour the emulsion obtained after emulsification into a homogenizer, set the pressure to 400-500 bar, and homogenize the emulsion 2-3 times, each time for 3-5 minutes. When the emulsion particles are fine, uniform and free of particles, stop homogenizing to obtain the main product emulsion. Step 4: Mixing The nanocapsule liposome solution obtained in step two is slowly added to the main product emulsion prepared in step three, while stirring at 600-800 rpm for 20-25 minutes to ensure that the nanocapsule liposomes can be uniformly dispersed in the emulsion, thereby obtaining the desired product. Step 5: Adjust the pH value Use a pH meter to measure the pH value of the product. If the pH value is not within the required range, adjust the pH value slowly with 0.1 mol / L citric acid solution or sodium hydroxide solution according to the measurement results. After stirring thoroughly, let it stand for 5-10 minutes to allow the pH value to stabilize before making the next measurement and adjustment until the pH value meets the requirements. Step Six: Filtering The product with the adjusted pH value is filtered through a 0.22μm microporous membrane to remove any small particles and impurities. Step 7: Filling The filtered product is then filled into clean packaging containers using a filling machine.
6. The preparation method of a fast-acting redness-reducing and repairing product according to claim 5, characterized in that: After each weighing, the balance pan of the electronic balance described in step two should be wiped with a clean paper towel.
7. The preparation method of a fast-acting redness-reducing and repairing product according to claim 5, characterized in that: When using a glass rod for stirring as described in step two, be careful not to let the glass rod touch the walls or bottom of the beaker.
8. The preparation method of a fast-acting redness-reducing and repairing product according to claim 5, characterized in that: After each homogenization process, the emulsion needs to be collected and its particle size distribution needs to be detected using a particle size analyzer.
9. A method for preparing a fast-acting redness-reducing and repairing product according to claim 5, characterized in that: The product pH value required in step five is between 5.5 and 6.0.
Citation Information
Cited By
Face repair system and face repair method
CN121883487A
