Production method and equipment of trifluoroacetamide

Abstract

The invention relates to a trifluoroacetamide production method and equipment, and relates to the technical field of trifluoroacetamide production equipment.The trifluoroacetamide production equipment comprises a rack, a feeding mechanism is arranged at the top of a premixing box on the rack, a premixing inner cavity is formed in the premixing box, and four cavity partition plates are fixedly installed on the outer wall of a center shaft in the premixing inner cavity; the premixing inner cavity is divided into four equal-volume material distribution cavities; a shaft ring seat is arranged on the outer side of the premixing box body, one end of the central shaft is arranged in the shaft ring seat and is in running fit with the shaft ring seat, the other end of the central shaft is fixedly connected with a power driving shaft, and a driving mechanism is mounted at the outer end part of the power driving shaft and is used for enabling the power driving shaft to intermittently rotate by 90 degrees. According to the invention, premixing operation of four formulas with different molar ratios can be completed in parallel, so that the equipment utilization rate and the production efficiency are greatly improved, a production line is endowed with relatively strong flexible output capability, and the production requirements of trifluoroacetamide products with different purity grades can be quickly responded.

Description

Technical Field

[0001] This invention relates to the technical field of trifluoroacetamide production equipment, and specifically discloses a method and equipment for producing trifluoroacetamide. Background Technology

[0002] In the continuous production of trifluoroacetamide, the pre-mixing of ethyl trifluoroacetate and tetrahydrofuran is a crucial pretreatment step. Its core purpose is to create optimal conditions for the subsequent efficient and safe reaction with anhydrous liquid ammonia. Ethyl trifluoroacetate, tetrahydrofuran, and anhydrous liquid ammonia are all liquids, and the storage temperature of anhydrous liquid ammonia is generally between -33°C and -43°C. Mixing these three into a homogeneous solution effectively eliminates flow fluctuations that may occur from multiple feed streams, ensuring a precise and constant molar ratio with liquid ammonia, thus laying the foundation for obtaining high-purity, high-yield products. Therefore, this pre-mixing step paves the way for a complex chemical reaction through a simple physical process and is a key link in achieving a safe, controllable, and efficient production process.

[0003] The invention disclosed in CN116571181A is a process for synthesizing trifluoroacetamide. The equipment used in this process includes a chassis, a protective cylinder, a reaction vessel, a first shell, and a second shell. The first shell contains a vertical rod and a spiral blade, and its outer wall has a first electric heating element and a liquid outlet for preheating ethyl trifluoroacetamide. The second shell contains a connecting pipe and an arc-shaped plate, and its outer wall has a second electric heating element. Ammonia gas is supplied to react with ethyl trifluoroacetamide via a conversion mechanism. In the aforementioned prior art, after a certain reaction time, a corrosion-resistant pump refluxes the reaction liquid to improve the conversion rate. After synthesis, the first and second shells can be switched via a rotating mechanism to wash them with water and then dried.

[0004] In publicly available patented technologies, preheating ethyl trifluoroacetate can improve the conversion rate and accelerate the production rate of trifluoroacetamide. However, using the aforementioned existing technology to premix the raw materials for trifluoroacetamide has significant limitations. Due to the single premixing tank, only one raw material molar ratio can be used in a single production cycle. This rigid production mode severely restricts process optimization and product diversification: switching to different ratios requires thorough equipment cleaning and parameter readjustment, a cumbersome and time-consuming process that results in low production efficiency and significant resource waste. More importantly, it is impossible to compare the reaction effects of multiple ratios under the same operating conditions, greatly extending the process development and optimization cycle and making it difficult to quickly respond to market demands for products of different purity levels. Summary of the Invention

[0005] To address the problem of low production efficiency caused by the rigid production mode in the current production process of trifluoroacetamide, this invention provides a method and equipment for producing trifluoroacetamide.

[0006] To address the above problems, in a first aspect, the present invention provides the following technical solution: A trifluoroacetamide production device includes a frame on which a premixing chamber is fixedly mounted. A feeding mechanism is located on the top of the premixing chamber. A premixing cavity is located inside the premixing chamber. The feeding mechanism is used to feed ethyl trifluoroacetate, anhydrous liquid ammonia, and tetrahydrofuran into the premixing cavity. A rotatable central shaft is located inside the premixing cavity. Four equally spaced partition plates are fixedly mounted on the outer wall of the central shaft. The outer edges of the partition plates slide against the inner wall of the premixing cavity, dividing the premixing cavity into four equal-volume distribution chambers. A collar seat, which is fastened to the frame, is located on the outside of the premixing chamber. One end of the central shaft is located inside the collar seat and rotatably engages with it. The other end of the central shaft is fixedly connected to a power drive shaft. A drive mechanism is installed on the outer end of the power drive shaft. The drive mechanism is used to intermittently rotate the power drive shaft by 90°. After each 90° rotation of the central shaft, one of the distribution chambers connects to the feeding mechanism.

[0007] Preferably, the feeding mechanism includes a manifold horizontal pipe, and a first flow vertical pipe and a second flow vertical pipe are fixedly installed at the bottom of the manifold horizontal pipe. The bottom ends of the first flow vertical pipe and the second flow vertical pipe are connected to the premixing cavity. A pipe disc is fixedly installed at one end of the manifold horizontal pipe. A damping pipe, a first high-pressure steel pipe, and a second high-pressure steel pipe are installed on the pipe disc. The damping pipe is connected to a third high-pressure steel pipe. The third high-pressure steel pipe is used to transport ethyl trifluoroacetate. The first high-pressure steel pipe and the second high-pressure steel pipe are used to transport anhydrous liquid ammonia and tetrahydrofuran, respectively.

[0008] Preferably, the end of the manifold horizontal pipe away from the pipe coil is provided with a first port and a second port, the first port and the second port are arranged radially perpendicularly, and a pressure relief pipe is provided on the side of the first port and fixedly installed on the pipe wall of the manifold horizontal pipe; a pressure valve is installed on the pipeline of the first high-pressure steel pipe.

[0009] Preferably, bearing seals are installed on both sides of the premixing chamber, and the bearing seals are fitted around the central shaft. Support seats that are fastened to the platform are provided on both sides of the premixing chamber. Rotary wheel bases are fixedly installed on the two support seats, and two rotary wheels are rotatably installed on each rotary wheel base. A support ring is fixedly fitted on the outer wall of the central shaft, and the outer wall of the rotary wheel slides in fit with the outer wall of the support ring.

[0010] Preferably, a first bearing seat and a second bearing seat are fixedly installed on the platform. A vertical plate is fixedly installed on the first bearing seat. The outer wall of the power drive shaft is rotatably engaged with the top of the vertical plate. A three-phase asynchronous motor is fixedly installed on the second bearing seat. The output end of the three-phase asynchronous motor is in transmission engagement with the drive mechanism.

[0011] Preferably, the drive mechanism includes a cam disk, one side of which is connected to the output end of a three-phase asynchronous motor. A groove is provided on one side of the cam disk. A cross bracket is fixedly installed at the end of the power drive shaft. Cylinders are fixedly installed on the outer sides of the four ends of the cross bracket. When the outer walls of two cylinders slide in cooperation with the inner walls of the groove, the other two cylinders are arranged on the outer side of the cam disk.

[0012] Preferably, a heart-shaped protrusion is provided on the side of the cam disk near the cross bracket, and the groove is arranged on the outside of the heart-shaped protrusion. The groove is a heart-shaped annular groove structure. Symmetrically arranged through slots are provided on both outer edges of the groove. The opening size of the through slots is adapted to the diameter of the cylinder. The sides of the two through slots are provided with inclined surfaces arranged on the cam disk. The inclined surfaces can slide and engage with the outer wall of the cylinder.

[0013] Preferably, a discharge box is fixedly installed at the bottom of the premix box, the top of the discharge box is connected to the premix inner cavity, the discharge box has a funnel-shaped structure, and the bottom of the discharge box is arranged inside the frame and is fastened to a third flow vertical pipe.

[0014] On the other hand, the present invention also provides a method for producing trifluoroacetamide, the method comprising: S1: Ethyl trifluoroacetate is delivered to one of the distribution chambers in the premixing cavity through the third high-pressure steel pipe, and the flow rate of ethyl trifluoroacetate is stabilized through the damping pipe. Anhydrous liquid ammonia and tetrahydrofuran are delivered to the above distribution chambers through the first high-pressure steel pipe and the second high-pressure steel pipe, respectively. The flow rates of ethyl trifluoroacetate, anhydrous liquid ammonia, and the molar ratio of tetrahydrofuran in the four distribution chambers are all different. S2: The cam disk is driven by a three-phase asynchronous motor to rotate continuously at a constant speed, causing two cylinders to slide in the groove. The cylinders can slide out of the groove through the through slot, causing the central shaft to rotate intermittently. After each rotation of 90°, each material distribution chamber stays below the feeding mechanism for a predetermined time to complete the conveying of ethyl trifluoroacetate, anhydrous liquid ammonia, and tetrahydrofuran. The partition plate can ensure that the materials in each chamber are independent and prevent cross-contamination. S3: During the intermittent rotation of the central shaft, ethyl trifluoroacetate, anhydrous liquid ammonia, and tetrahydrofuran are premixed in four dispensing chambers to form four molar ratios of trifluoroacetamide. The four molar ratios of trifluoroacetamide in the four dispensing chambers are discharged through the unloading box and the third flow vertical pipe.

[0015] Preferably, the four trifluoroacetamide molar ratio schemes in the four dispensing chambers are as follows: Option 1: Ethyl trifluoroacetate: anhydrous liquid ammonia: tetrahydrofuran = 1:1.0:4.5; Option 2: Ethyl trifluoroacetate: anhydrous liquid ammonia: tetrahydrofuran = 1:1.2:2.3; Option 3: Ethyl trifluoroacetate: anhydrous liquid ammonia: tetrahydrofuran = 1:1.6:9.2; Option 4: Ethyl trifluoroacetate: anhydrous liquid ammonia: tetrahydrofuran = 1:0.8:4.5.

[0016] Compared with the prior art, the present invention has the following beneficial effects: 1. This invention sets up four independent dispensing chambers separated by a central shaft and four partition plates in the premixing chamber, and uses a precision drive mechanism composed of a cam plate, a cross bracket and a cylinder to achieve precise indexing motion of the central shaft intermittently rotating 90°. The above structure allows the four dispensing chambers to flow sequentially to the bottom of the feeding mechanism, thereby continuously receiving raw materials with different proportions. During this period, each dispensing chamber is equivalent to an independent micro premixing reaction unit. Thus, within one set of equipment and one continuous production cycle, the premixing operation of four different molar ratio formulations can be completed in parallel. This not only greatly improves the equipment utilization rate and production efficiency, but also gives the production line a strong flexible output capability, which can quickly respond to the market's production demand for trifluoroacetamide products with different purity levels and properties, and improve the overall production efficiency of trifluoroacetamide. 2. The three high-pressure steel pipes in this invention transport three raw materials respectively. The ethyl trifluoroacetate pipe is specially equipped with a damping pipe, which can effectively smooth the pulse generated by the metering pump and ensure stable flow. The pressure valve installed on the anhydrous liquid ammonia pipe can monitor the pipeline pressure in real time. The pressure relief pipe set on the manifold provides an emergency pressure relief channel for the system. The above design structure together ensures the smoothness and safety of the feeding process. At the same time, the premixing cavity is designed as a circle and placed in a square box. The buffer space formed provides a safety margin for the expansion of the cavity in abnormal situations. Furthermore, the central shaft and the partition plate can maintain the seal under dynamic rotation, effectively preventing cross-contamination of materials between the various distribution cavities. This ensures that the raw materials of the four proportion schemes can be accurately and independently transported and premixed, creating a safe operating environment and reducing the risks in the production process to a controllable range. 3. This invention provides a highly efficient parallel experimental platform, enabling technicians to set up four candidate formulations at once. Utilizing the intermittent rotation mechanism of the equipment, these formulations are premixed synchronously under the same macroscopic operating conditions, resulting in four products of different purities. These products can be directly compared and analyzed, allowing for the rapid and accurate selection of the optimal process parameters. This production mode transforms the traditional sequential trial-and-error process into a parallel comparative optimization, significantly shortening the cycle from laboratory research and development to industrial-scale production. It provides a powerful technical tool for the continuous improvement of trifluoroacetamide production processes and the development of new formulations, demonstrating significant scientific research and application value. Attached Figure Description

[0017] To more clearly illustrate the technical solution of the present invention, the drawings used in the description will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort. Figure 1 This is a schematic diagram of the overall structure of the production equipment of the present invention; Figure 2 This is a schematic diagram of the premixed container structure of the present invention; Figure 3 This is a schematic diagram of the cavity plate mounting structure of the present invention; Figure 4 This is a detailed structural diagram of the feeding mechanism of the present invention; Figure 5 This is a schematic diagram of the central shaft mounting structure of the present invention; Figure 6 This is a schematic diagram of the power drive shaft mounting structure of the present invention; Figure 7 This is a detailed structural diagram of the drive mechanism of the present invention; Figure 8 This is a schematic diagram of the cam disk structure of the present invention; In the diagram: 1. Platform, 2. Premixing chamber, 3. Feeding mechanism, 301. Manifold horizontal pipe, 302. First flow vertical pipe, 303. Second flow vertical pipe, 304. Pipe coil, 305. Damping pipe, 306. First high-pressure steel pipe, 307. Second high-pressure steel pipe, 308. Third high-pressure steel pipe, 309. First port, 310. Second port, 311. Pressure relief pipe, 312. Pressure valve gauge, 4. Premixing cavity, 5. Central shaft, 6. Baffle plate, 7. Distributing cavity, 8. Shaft collar seat. 9. Power drive shaft, 10. Drive mechanism, 1001. Cam plate, 1002. Groove, 1003. Cross bracket, 1004. Cylindrical, 1005. Heart-shaped protrusion, 1006. Through slot, 1007. Beveled surface, 11. Bearing seal ring, 12. Support seat, 13. Rotary wheel base, 14. Rotary wheel, 15. Support ring, 16. First bearing seat, 17. Second bearing seat, 18. Vertical plate, 19. Three-phase asynchronous motor, 20. Unloading box, 21. Third flow vertical pipe. Detailed Implementation

[0018] To make the objectives, features, and advantages of this invention more apparent and understandable, the technical solutions of this invention will be clearly and completely described below with reference to the accompanying drawings of the specific embodiments. Obviously, the embodiments described below are only some embodiments of this invention, and not all embodiments. Based on the embodiments of this invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this invention.

[0019] This specific embodiment provides a production equipment for trifluoroacetamide, such as... Figures 1-8 As shown, it includes a platform 1, which is composed of two layers of beams with a gap in between. A premixing box 2 is fixedly installed on the platform 1. The premixing box 2 has a square structure and a circular inner cavity inside, which is the premixing inner cavity 4. The space between the premixing inner cavity 4 and the outer shell of the premixing box 2 is a buffer structure, which can provide a safe buffer space for the expansion of the premixing inner cavity 4.

[0020] The premixing chamber 2 is equipped with a feeding mechanism 3 at its top. The feeding mechanism 3 includes a manifold horizontal pipe 301, which is arranged above the premixing chamber 2. A first flow vertical pipe 302 and a second flow vertical pipe 303 are fixedly installed at the bottom of the manifold horizontal pipe 301. The bottom ends of the first flow vertical pipe 302 and the second flow vertical pipe 303 pass through the outer shell of the premixing chamber 2 and are connected to the premixing inner cavity 4. A pipe disc 304 is fixedly installed at one end of the manifold horizontal pipe 301. A damping pipe 305, a first high-pressure steel pipe 306, and a second high-pressure steel pipe 307 are installed on the pipe disc 304. The damping pipe 305 is arranged in the center of the pipe disc 304, and the first high-pressure steel pipe 306 and the second high-pressure steel pipe 307 are arranged at the edge of the pipe disc 304. The damping pipe 305 is connected to a third high-pressure steel pipe 308. The inlet of the third high-pressure steel pipe 308 is connected to an ethyl trifluoroacetate conveying device. Ethyl trifluoroacetate can be conveyed into the premixing cavity 4 through the third high-pressure steel pipe 308 and the damping pipe 305. The first high-pressure steel pipe 306 and the second high-pressure steel pipe 307 are respectively connected to the conveying devices for anhydrous liquid ammonia and tetrahydrofuran, so that the first high-pressure steel pipe 306 and the second high-pressure steel pipe 307 convey anhydrous liquid ammonia and tetrahydrofuran into the premixing cavity 4, respectively.

[0021] The manifold 301, located away from the pipe coil 304, has a first port 309 and a second port 310. The first port 309 is oriented in the same direction as the diameter of the manifold 301, and the ports of the first port 309 and the second port 310 are arranged radially perpendicularly. The first port 309 and the second port 310 provide multiple temporary docking ports for the manifold 301, facilitating the temporary addition of other raw materials during trifluoroacetamide production. A pressure gauge 312 is installed on the first high-pressure steel pipe 306 to facilitate real-time monitoring of the flow pressure within the first high-pressure steel pipe 306, ensuring that the internal pressure of the manifold 301 remains within a safe range. A pressure relief pipe 311 is fixedly installed on the wall of the manifold 301 at the side of the first port 309, providing a working structure for emergency pressure relief of the manifold 301.

[0022] Both sides of the premixing chamber 2 are provided with circular openings for the central shaft 5 to pass through. Bearing seals 11 are installed on the outer sides of the two circular openings, and the bearing seals 11 are fitted around the central shaft 5 to ensure the airtightness of the premixing chamber 2, forming a dynamic sealing fit between the central shaft 5 and the premixing chamber 2. Both sides of the premixing chamber 2 are provided with support seats 12 that are securely connected to the frame 1. The two support seats 12 are symmetrically arranged and each has a fixedly mounted rotating wheel base 13. Two rotating wheels 14 are rotatably mounted on each rotating wheel base 13, and each rotating wheel 14 is arranged below and parallel to the central shaft 5. A support ring 15 is fixedly fitted onto the outer wall of the central shaft 5. The outer wall of each rotating wheel 14 has a trapezoidal groove that matches the width of the support ring 15, allowing the outer wall of each rotating wheel 14 to slide against the outer wall of the support ring 15, thus providing an effective support structure for the rotation of the central shaft 5.

[0023] The premixing chamber 2 has a collar seat 8 on its left exterior, which is fastened to the platform 1. One end of the central shaft 5 is located inside the collar seat 8 and rotates with it, providing a support structure for the rotation of the central shaft 5. A first bearing seat 16 and a second bearing seat 17 are fixedly installed on the top right side of the platform 1. A vertical plate 18 is fixedly installed on the first bearing seat 16. A power drive shaft 9 is fixedly connected to one end of the central shaft 5. The outer wall of the power drive shaft 9 rotates with the top of the vertical plate 18, providing a support structure for the rotation of the power drive shaft 9 via the vertical plate 18 and the first bearing seat 16. A three-phase asynchronous motor 19 is fixedly installed on the second bearing seat 17. The output end of the three-phase asynchronous motor 19 is driven by the power drive shaft 9 through a drive mechanism 10.

[0024] The drive mechanism 10 includes a cam disk 1001, which is circular. One side of the cam disk 1001 is connected to the output end of the three-phase asynchronous motor 19 via a coupling. A heart-shaped protrusion 1005 is provided on the other side of the cam disk 1001, and a groove 1002, which is a heart-shaped annular groove structure, is provided around the periphery of the heart-shaped protrusion 1005. A cross bracket 1003 is fixedly installed on the end of the power drive shaft 9 near the three-phase asynchronous motor 19. Cylindrical cylinders 1004 are fixedly installed on the outer sides of the four ends of the cross bracket 1003 (upper, lower, left, and right), and the four cylinders 1004 are arranged parallel to the power drive shaft 9. The outer edges of both sides of the groove 1002 are provided with symmetrically arranged through slots 1006. The opening size of the through slots 1006 is adapted to the diameter of the cylinder 1004. The sides of both through slots 1006 are provided with inclined surfaces 1007 arranged on the cam disk 1001. The inclined surfaces 1007 can slide with the outer wall of the cylinder 1004. When the outer walls of two cylinders 1004 slide with the inner wall of the groove 1002, the other two cylinders 1004 can slide with the inner wall of the groove 1002. 04 is arranged on the outside of the cam disk 1001. When one of the cylinders 1004 slides out of the cam disk 1001 through one of the through slots 1006, the adjacent cylinders 1004 (except for the cylinders 1004 in the groove 1002) slide into the groove 1002 through the other through slot 1006. When the cam disk 1001 rotates, under the transmission action of the cross bracket 1003, the power drive shaft 9 rotates intermittently by 90°. After each 90° rotation, a partial interval can be retained.

[0025] Four equally spaced partition plates 6 are fixedly installed on the outer wall of the central shaft 5. The outer edges of the partition plates 6 slide against the inner wall of the premixing cavity 4, and a dynamic sealing structure is formed by setting an oil film on the inner wall of the premixing cavity 4. The four equally spaced partition plates 6 divide the premixing cavity 4 into four equal-volume distribution chambers 7, so that the four distribution chambers 7 can receive ethyl trifluoroacetate, anhydrous liquid ammonia, and tetrahydrofuran from the feeding mechanism 3. A discharge box 20 is fixedly installed at the bottom of the premixing box 2. The top of the discharge box 20 is provided with an automatic material gate and is connected to the premixing cavity 4. The discharge box 20 has a funnel-shaped structure. The bottom end of the discharge box 20 is arranged inside the frame 1 and is fastened to a third flow vertical pipe 21. By controlling the opening and closing of the automatic material gate, the flow rate of the premixed raw materials flowing out of the distribution chambers 7 is controlled, so as to control the overall outflow of the equipment.

[0026] The foregoing has described in detail an embodiment of a trifluoroacetamide production equipment. Based on the trifluoroacetamide production equipment described in the above embodiment, this invention also provides a method for producing trifluoroacetamide corresponding to the equipment, comprising the following steps: S1: Ethyl trifluoroacetate is supplied to one of the distribution chambers 7 in the premixing chamber 4 through the third high-pressure steel pipe 308, and the flow rate of ethyl trifluoroacetate is stabilized through the damping pipe 305 to keep it in a continuous and stable supply environment. Anhydrous liquid ammonia and tetrahydrofuran are supplied to the above-mentioned distribution chamber 7 through the first high-pressure steel pipe 306 and the second high-pressure steel pipe 307, respectively, and the pressure inside the pipeline is monitored in real time through the pressure valve gauge 312. The flow rates of ethyl trifluoroacetate, anhydrous liquid ammonia, and the molar ratio of tetrahydrofuran in the four distribution chambers 7 are all different. The four trifluoroacetamide molar ratio schemes in the four dispensing chambers 7 are as follows: Option 1: Ethyl trifluoroacetate: anhydrous liquid ammonia: tetrahydrofuran = 1:1.0:4.5; Option 2: Ethyl trifluoroacetate: anhydrous liquid ammonia: tetrahydrofuran = 1:1.2:2.3; Option 3: Ethyl trifluoroacetate: anhydrous liquid ammonia: tetrahydrofuran = 1:1.6:9.2; Option 4: Ethyl trifluoroacetate: anhydrous liquid ammonia: tetrahydrofuran = 1:0.8:4.5.

[0027] S2: The cam disk 1001 is driven by a three-phase asynchronous motor 19 to rotate continuously at a uniform speed, causing two cylinders 1004 to slide in the groove 1002. One of the cylinders 1004 can slide out of the groove 1002 through the through slot 1006, causing the central shaft 5 to rotate intermittently. After each rotation of 90°, each material distribution chamber 7 stays below the feeding mechanism 3 for a predetermined time, which can be controlled between 15s and 20s. After multiple intermittent rotations of the central shaft 5, the conveying of ethyl trifluoroacetate, anhydrous liquid ammonia, and tetrahydrofuran is completed. The partition plate 6 can ensure that the materials in each chamber are independent and prevent cross-contamination.

[0028] S3: During the intermittent rotation of the central shaft 5, ethyl trifluoroacetamide, anhydrous liquid ammonia, and tetrahydrofuran are premixed in four dispensing chambers 7 to form four molar ratios of trifluoroacetamide. The trifluoroacetamide produced by Scheme 1 is expected to have a purity of 97%-98%, containing a small amount of unreacted ethyl trifluoroacetamide impurities. It can be used in pesticide synthesis and as a general chemical intermediate, and is considered a medium-value product. The trifluoroacetamide produced by Scheme 2 is expected to have a purity greater than 99.5%, high purity, stable quality, and is a white crystalline powder. It can be used in pesticides, pharmaceutical intermediates, and materials science, and is considered a high-value product. The trifluoroacetamide produced by Scheme 3 is expected to have a purity greater than 99.9%, possessing ultra-high purity characteristics and extremely low impurity content. It can be used in high-end pharmaceuticals, electronic chemicals, and analytical reagents, and is considered an extremely high-value product. The trifluoroacetamide produced by Scheme 4 is expected to have a purity less than 95%, poor purity, and contains a large amount of impurities. It can be used in recycled products and is considered a by-product of secondary utilization. The four molar ratios of trifluoroacetamide in the four dispensing chambers 7 are discharged through the unloading box 20 and the third flow vertical pipe 21.

[0029] If you want to enter the high-value-added pharmaceutical and materials market, you must choose a process that can stably produce products with a purity of ≥99.5%, and you can use Option 2; if you want to pursue the cutting-edge electronic chemicals market, you need to use Option 3; if you want to consider the low-end market, you can use Option 1; if you need to provide reactants for secondary recycling, you can use Option 4.

[0030] The above description of the disclosed embodiments enables those skilled in the art to make or use the invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the general principles defined herein may be implemented in other embodiments without departing from the spirit or scope of the invention. Therefore, the invention is not to be limited to the embodiments shown herein, but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.

Claims

1. A production apparatus for trifluoroacetamide, comprising a frame (1), characterized in that, A premixing chamber (2) is fixedly installed on the frame (1). A feeding mechanism (3) is provided on the top of the premixing chamber (2). A premixing cavity (4) is provided inside the premixing chamber (2). The feeding mechanism (3) is used to feed ethyl trifluoroacetate, anhydrous liquid ammonia, and tetrahydrofuran into the premixing cavity (4). A rotatable central shaft (5) is provided inside the premixing cavity (4). Four equally spaced partition plates (6) are fixedly installed on the outer wall of the central shaft (5). The outer edge of the partition plates (6) slides against the inner wall of the premixing cavity (4). The four equally spaced partition plates (6) will... The premixed inner cavity (4) is divided into four equal-volume dispensing cavities (7); the outer side of the premixed box (2) is provided with a collar seat (8) that is fastened to the frame (1), one end of the central shaft (5) is arranged inside the collar seat (8) and rotates with it, the other end of the central shaft (5) is fixedly connected to a power drive shaft (9), and a drive mechanism (10) is installed at the outer end of the power drive shaft (9). The drive mechanism (10) is used to make the power drive shaft (9) rotate intermittently by 90°. After the central shaft (5) rotates 90°, one of the dispensing cavities (7) is connected to the feeding mechanism (3).

2. The trifluoroacetamide production equipment according to claim 1, characterized in that, The feeding mechanism (3) includes a manifold (301), and a first flow vertical pipe (302) and a second flow vertical pipe (303) are fixedly installed at the bottom of the manifold (301). The bottom ends of the first flow vertical pipe (302) and the second flow vertical pipe (303) are connected to the premixing cavity (4). A pipe disc (304) is fixedly installed at one end of the manifold (301). A damping pipe (305), a first high-pressure steel pipe (306), and a second high-pressure steel pipe (307) are installed on the pipe disc (304). The damping pipe (305) is connected to a third high-pressure steel pipe (308). The third high-pressure steel pipe (308) is used to transport ethyl trifluoroacetate. The first high-pressure steel pipe (306) and the second high-pressure steel pipe (307) are used to transport anhydrous liquid ammonia and tetrahydrofuran, respectively.

3. The trifluoroacetamide production equipment according to claim 2, characterized in that, The manifold (301) has a first port (309) and a second port (310) at the end away from the pipe coil (304). The first port (309) and the second port (310) are arranged radially perpendicularly. A pressure relief pipe (311) is fixedly installed on the pipe wall of the manifold (301) at the side of the first port (309). A pressure valve (312) is installed on the pipeline of the first high-pressure steel pipe (306).

4. The trifluoroacetamide production equipment according to claim 1, characterized in that, The premix box (2) is equipped with bearing seals (11) on both sides. The bearing seals (11) are fitted around the central shaft (5). The premix box (2) is provided with support seats (12) that are fastened to the frame (1) on both sides. Rotary wheel bases (13) are fixedly installed on the two support seats (12). Two rotating wheels (14) are rotatably installed on each rotating wheel base (13). A support ring (15) is fixedly fitted on the outer wall of the central shaft (5). The outer wall of the rotating wheel (14) slides with the outer wall of the support ring (15).

5. The trifluoroacetamide production equipment according to claim 1, characterized in that, The platform (1) is fixedly installed with a first bearing seat (16) and a second bearing seat (17). A vertical plate (18) is fixedly installed on the first bearing seat (16). The outer wall of the power drive shaft (9) is rotatably engaged with the top of the vertical plate (18). A three-phase asynchronous motor (19) is fixedly installed on the second bearing seat (17). The output end of the three-phase asynchronous motor (19) is engaged with the drive mechanism (10) in a transmission manner.

6. The trifluoroacetamide production equipment according to claim 5, characterized in that, The drive mechanism (10) includes a cam disk (1001), one side of which is connected to the output end of a three-phase asynchronous motor (19). A groove (1002) is provided on one side of the cam disk (1001). A cross bracket (1003) is fixedly installed at the end of the power drive shaft (9). Cylinders (1004) are fixedly installed on the outer sides of the four ends of the cross bracket (1003). When the outer walls of two cylinders (1004) slide with the inner walls of the groove (1002), the other two cylinders (1004) are arranged on the outer side of the cam disk (1001).

7. The trifluoroacetamide production equipment according to claim 6, characterized in that, The cam disk (1001) has a heart-shaped protrusion (1005) on the side of the disk near the cross bracket (1003). The groove (1002) is arranged on the outside of the heart-shaped protrusion (1005). The groove (1002) is a heart-shaped annular groove structure. Symmetrically arranged through slots (1006) are opened on both outer edges of the groove (1002). The opening size of the through slots (1006) is adapted to the diameter of the cylinder (1004). The sides of the two through slots (1006) are provided with inclined surfaces (1007) arranged on the cam disk (1001). The inclined surfaces (1007) can slide with the outer wall of the cylinder (1004).

8. The trifluoroacetamide production equipment according to claim 1, characterized in that, The bottom of the premix box (2) is fixedly installed with a discharge box (20). The top of the discharge box (20) is connected to the premix inner cavity (4). The discharge box (20) has a funnel-shaped structure. The bottom of the discharge box (20) is arranged inside the frame (1) and is tightly connected to a third flow vertical pipe (21).

9. A method for producing trifluoroacetamide, comprising the trifluoroacetamide production equipment according to any one of claims 1-8, characterized in that, The method includes: S1: Ethyl trifluoroacetate is delivered to one of the distribution chambers (7) in the premixed inner cavity (4) through the third high-pressure steel pipe (308), and the flow rate of ethyl trifluoroacetate is stabilized through the damping pipe (305). Anhydrous liquid ammonia and tetrahydrofuran are delivered to the above distribution chambers (7) through the first high-pressure steel pipe (306) and the second high-pressure steel pipe (307) respectively. The flow rates of ethyl trifluoroacetate, anhydrous liquid ammonia, and the molar ratio of tetrahydrofuran in the four distribution chambers (7) are all different. S2: The cam disk (1001) is driven by a three-phase asynchronous motor (19) to rotate continuously at a constant speed, so that two cylinders (1004) slide in the groove (1002). The cylinders (1004) can slide out of the groove (1002) through the through slot (1006), so that the central shaft (5) rotates intermittently. After each rotation of 90°, each material distribution chamber (7) stays below the feeding mechanism (3) for a predetermined time to complete the conveying of ethyl trifluoroacetate, anhydrous liquid ammonia, and tetrahydrofuran. The partition plate (6) can ensure that the materials in each chamber are independent and prevent cross-contamination. S3: During the intermittent rotation of the central shaft (5), ethyl trifluoroacetate, anhydrous liquid ammonia, and tetrahydrofuran are premixed in four distribution chambers (7) to form four molar ratios of trifluoroacetamide. The four molar ratios of trifluoroacetamide in the four distribution chambers (7) are discharged through the unloading box (20) and the third flow vertical pipe (21).

10. A method for producing trifluoroacetamide according to claim 9, characterized in that, The four trifluoroacetamide molar ratio schemes in the four dispensing chambers (7) are as follows: Option 1: Ethyl trifluoroacetate: anhydrous liquid ammonia: tetrahydrofuran = 1:1.0:4.5; Option 2: Ethyl trifluoroacetate: anhydrous liquid ammonia: tetrahydrofuran = 1:1.2:2.3; Option 3: Ethyl trifluoroacetate: anhydrous liquid ammonia: tetrahydrofuran = 1:1.6:9.2; Option 4: Ethyl trifluoroacetate: anhydrous liquid ammonia: tetrahydrofuran = 1:0.8:4.5.

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