Grinding device for biochemical laboratory

Abstract

The invention discloses a grinding device for a biochemical laboratory, and belongs to the technical field of laboratory grinding. The grinding device comprises a shell, and a first grinding assembly and a second grinding assembly are arranged in a first grinding cavity and a second grinding cavity in the shell correspondingly; a baffle is arranged between the first grinding cavity and the second grinding cavity, a through hole is formed in the middle of the baffle, and a circulation cavity is formed between the connecting shaft and the inner wall of the through hole. The second grinding assembly comprises a guide barrel, a rotating ring sleeves the guide barrel, the lower end of the connecting shaft extends into the guide barrel, a mounting column is arranged at the lower end of the guide barrel, a discharging opening is formed in the side wall of the guide barrel, and a grinding rod is movably connected to the lower end of the mounting column. The double-grinding-cavity step-by-step grinding design is adopted, primary treatment is conducted through the first grinding assembly, then fine grinding is conducted through the second grinding assembly, coarse-to-fine gradient grinding of sample materials can be achieved, the grinding uniformity and fineness are remarkably improved, and the high-precision requirement of biochemical experiments for the sample particle size is met.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of laboratory grinding, more particularly to a grinding device for biochemical laboratory. BACKGROUND

[0002] In biochemical experiments, sample grinding as a key pretreatment link, its efficiency and accuracy directly affect the reliability of subsequent molecular extraction, enzyme activity analysis and other experimental results. The traditional grinding technology has multiple limitations: manual mortar relies on manpower, low efficiency and uneven force; electric homogenizer has insufficient flux, which is difficult to cope with high-throughput experiments; mechanical grinder supports parallel processing, but needs to frequently replace the medium. Temperature control is a major problem, the heat generated by grinding can cause the sample to heat up, threatening the stability of nucleic acids. Although there is liquid nitrogen pre-cooling technology, but the operation is easy to cause sample loss and pollution. At the same time, the traditional equipment is not completely broken for tough tissue, such as low DNA extraction rate of manually ground wheat leaves. In view of this, we propose a grinding device for biochemical laboratory. SUMMARY

[0003] The purpose of the present application is to provide a grinding device for biochemical laboratory to solve the problems raised in the background art.

[0004] To achieve the above purpose, the present application provides the following technical scheme: A grinding device for biochemical laboratory, comprising a shell, a first temperature control mechanism is arranged in the shell, a first grinding cavity and a second grinding cavity are arranged in the shell, a first grinding assembly and a second grinding assembly are respectively arranged in the first grinding cavity and the second grinding cavity; The first grinding assembly comprises a mounting shaft, a crushing knife is arranged on the mounting shaft, a connecting shaft is connected to the lower end of the mounting shaft, and strip-shaped blades are arranged at equal intervals on the outer wall of the connecting shaft in a ring shape; A baffle is arranged between the first grinding cavity and the second grinding cavity, a through hole is formed in the middle of the baffle, the connecting shaft extends into the through hole, and a flow-through cavity is formed between the connecting shaft and the inner wall of the through hole, the top surface of the baffle is inclined, and the inclined surface is inclined downward toward one side of the through hole; The second grinding assembly comprises a material guide cylinder, a rotating ring is arranged on the outer sleeve of the material guide cylinder, the lower end of the connecting shaft extends into the material guide cylinder, an installation column is arranged at the lower end of the material guide cylinder, a discharge port is formed in the side wall of the installation column, the discharge port communicates with the material guide cylinder, and a grinding rod is movably connected to the lower end of the installation column.

[0005] Preferably, a second temperature control mechanism is arranged in the grinding rod, the second temperature control mechanism comprises a second pipe body arranged in the grinding rod, a fixed pipe is connected to the second pipe body, a guide pipe is rotatably connected to the upper end of the fixed pipe, the guide pipe extends to the outside of the shell through the installation column, the connecting shaft and the mounting shaft in sequence, and the guide pipe is rotatably connected with the installation column, the connecting shaft and the mounting shaft.

[0006] Preferably, an inner sleeve is rotatably fitted inside the guide pipe, the lower end of the inner sleeve extends into the fixed pipe and connects to the fixed pipe, and two inlet and outlet water pipes are provided inside the inner sleeve; The lower end of the inner sleeve is designed as a telescopic structure, and the fixed tube has an installation cavity near the upper end. The guide tube extends into the installation cavity and slides into the installation cavity.

[0007] Preferably, a sliding groove is provided on both sides of the bottom surface of the rotating ring, a slider is provided in the sliding groove, and a threaded rod is provided through the sliding groove, with the threaded rod and the slider being threadedly engaged; The grinding rod is provided with mounting bases on both sides, and a support column is rotatably connected to the mounting base. The support column is inclined and the upper end of the support column is rotatably connected to the slider.

[0008] Preferably, the grinding rod has a mounting groove, a spring is installed in the mounting groove, and the lower end of the mounting post extends into the mounting groove and connects with the spring.

[0009] Preferably, the first temperature control mechanism includes a first tube body disposed inside the housing, and an input tube and an output tube are connected to the first tube body, with the input tube and the output tube extending to the outside of the housing.

[0010] Preferably, the housing includes an upper cover, a middle housing, and a lower housing, with a feed inlet on the upper cover and the middle housing being movably connected to the upper cover and the lower housing.

[0011] Preferably, a first driving mechanism is installed at the upper end of the housing, and the first driving mechanism is used to drive the first grinding assembly to rotate; A second drive mechanism is installed on the baffle, which is used to drive the second grinding assembly to rotate.

[0012] Preferably, the first drive mechanism includes a first motor, a first gear and a second gear. The output shaft of the first motor is connected to the first gear, the first gear and the second gear mesh, and a gear shaft is provided in the middle of the second gear, which extends into the first grinding chamber and is connected to the mounting shaft.

[0013] Preferably, the second drive mechanism includes a second motor, a gear ring, and a third gear. The second motor is disposed inside the baffle, the gear ring and the third gear mesh, and the gear ring is mounted on the top surface of the rotating ring.

[0014] Compared with the prior art, the beneficial effects of the present invention are as follows: (1) The present application adopts a double-grinding-cavity step-by-step grinding design, which can realize gradient grinding of sample materials from coarse to fine through preliminary processing by the first grinding assembly and fine grinding by the second grinding assembly, significantly improve grinding uniformity and fineness, and meet the high-precision requirements of biochemical experiments on sample particle size. The first temperature control mechanism can control the internal environmental temperature of the shell in real time to avoid loss of biological activity or change of chemical properties of the sample due to grinding heat production, effectively protecting the integrity of the sample. The flow-through cavity structure formed by the baffle and the connecting shaft not only physically separates the two grinding cavities but also provides a directional channel for sample transmission, avoiding sample residue accumulation.

[0015] (2) The material guide cylinder of the second grinding assembly of the present application can guide the directional flow of the sample to avoid sample loss caused by random splashing in the cavity. When the rotating ring drives the grinding rod to rotate, it can form an annular grinding track, which, in combination with the restraining action of the material guide cylinder, allows the sample to be subjected to uniform grinding force. The adjusting structure of the sliding block and the threaded rod can flexibly change the inclination angle of the support column, thereby accurately controlling the pressure of the grinding rod on the sample and realizing adaptive grinding of samples with different hardness. The elastic cooperation structure of the spring and the mounting column can automatically compensate for the volume change of the sample during grinding, ensuring that the grinding rod always maintains effective contact with the sample and avoiding the phenomenon of empty grinding.

[0016] (3) The first temperature control mechanism of the present application can maintain a constant temperature environment in all directions, which is suitable for long-term grinding of a large number of samples and avoids temperature accumulation. The second temperature control mechanism directly cools the grinding rod through an independent pipeline, which can control the temperature of the grinding contact area in a targeted manner to avoid excessive local friction heat that can damage the components of heat-sensitive samples. The rotating pipeline design ensures that the grinding rod rotates without interference, ensuring the continuity of temperature control and the smoothness of grinding action. BRIEF DESCRIPTION OF DRAWINGS

[0017] Figure 1 is a schematic diagram of the overall structure of the present application; Figure 2 is a schematic diagram of the internal structure of the shell of the present application; Figure 3 is a schematic diagram of the structure of the second grinding assembly of the present application; Figure 4 is a side view schematic diagram of the second grinding assembly of the present application; Figure 5 is a cross-sectional structure schematic diagram of the mounting column and the guide tube of the present application; Figure 6 is a cross-sectional structure schematic diagram of the fixed tube of the present application; Figure 7 is a schematic diagram of the Figure 3Schematic view of the local enlargement.

[0018] Explanation of reference numerals in the drawing: 1, housing; 101, first grinding cavity; 102, second grinding cavity; 103, baffle; 104, through hole; 105, feed inlet; 2, first grinding assembly; 201, mounting shaft; 202, crushing knife; 203, connecting shaft; 204, strip blade; 3, second grinding assembly; 301, guide cylinder; 302, rotating ring; 303, mounting column; 304, grinding rod; 305, chute; 306, sliding block; 307, threaded rod; 308, mounting seat; 309, support column; 310, mounting groove; 311, spring; 4, first temperature control mechanism; 5, first driving mechanism; 501, first motor; 502, gear one; 503, gear two; 6, second driving mechanism; 7, second temperature control mechanism; 701, second tube body; 702, fixed tube; 703, guide tube; 704, inner sleeve; 705, water inlet and outlet pipe. DETAILED DESCRIPTION

[0019] The technical solutions in the embodiments of the present application will be described clearly and completely below with reference to the accompanying drawings in the embodiments of the present application. Obviously, the described embodiments are only some of the embodiments of the present application, but not all the embodiments. EMBODIMENT

[0020] Please refer to Figures 1-7 A grinding device for biochemical laboratory, comprising a housing 1, a first temperature control mechanism 4 is arranged in the housing 1, a first grinding cavity 101 and a second grinding cavity 102 are arranged in the housing 1, a first grinding assembly 2 and a second grinding assembly 3 are respectively arranged in the first grinding cavity 101 and the second grinding cavity 102; the sample material to be ground is first placed in the first grinding cavity 101 and ground by the first grinding assembly 2, and then enters the second grinding cavity 102 for further fine grinding by the second grinding assembly 3. The design of double-grinding cavities for step-by-step grinding can realize the gradient grinding of the sample material from coarse to fine, significantly improve the uniformity and fineness of grinding, and meet the high-precision requirements of biochemical experiments on the particle size of the sample. The first temperature control mechanism 4 can real-time control the environmental temperature in the housing, avoid the loss of biological activity or the change of chemical properties of the sample due to grinding heat, and effectively protect the integrity of the sample.

[0021] The first grinding assembly 2 comprises a mounting shaft 201, a crushing knife 202 arranged on the mounting shaft 201, and a connecting shaft 203 connected to the lower end of the mounting shaft 201, wherein the outer wall of the connecting shaft 203 is annular and equidistantly provided with strip-shaped blades 204, and the connecting shaft 203 and the strip-shaped blades 204 are driven to rotate when the mounting shaft 201 rotates; the first driving mechanism 5 is arranged at the upper end of the shell 1 and is used to drive the first grinding assembly 2 to rotate; the mounting shaft 201 is driven to rotate by the first driving mechanism 5, so that the crushing knife 202 is driven to rotate by the mounting shaft 201 to cut the sample material. The first grinding assembly 2 quickly cuts the sample by the crushing knife 202, and the shear force formed by the rotation of the connecting shaft 203 can complete the preliminary crushing of a large amount of samples in a short time and greatly improve the grinding efficiency. The first driving mechanism 5 adopts a gear transmission mode, can provide stable torque output, ensures continuous and efficient operation of the crushing knife 202, and reduces the problem of uneven grinding caused by power fluctuation.

[0022] The first grinding cavity 101 and the second grinding cavity 102 are provided with a baffle 103, the middle part of the baffle 103 is provided with a through hole 104, the connecting shaft 203 extends into the through hole 104, and a flow passage is formed between the connecting shaft 203 and the inner wall of the through hole 104; the sample material ground by the first grinding assembly 2 flows into the second grinding cavity 102 through the flow passage, and the strip-shaped blades 204 arranged on the connecting shaft 203 further cut the sample material when the cut sample material flows through the flow passage, which is convenient for subsequent grinding. The flow passage structure formed by the baffle 103 and the connecting shaft 203 not only realizes the physical separation of the two grinding cavities, but also provides a directional channel for sample transmission, avoiding sample residue accumulation. The strip-shaped blades 204 rotate synchronously in the flow passage, and the cut sample is subjected to secondary shearing, so that the sample particle size is further homogenized, the energy consumption and time cost of subsequent fine grinding are reduced, and the wear of the second grinding assembly 3 caused by large-particle samples is reduced.

[0023] The top surface of the baffle 103 is provided as an inclined surface, and the inclined direction of the inclined surface is gradually downwardly inclined to one side of the through hole 104.

[0024] In a possible embodiment, a vibration motor is arranged in the baffle 103 to generate a vibration force on the baffle 103, so that the grinding material on the baffle 103 can fall down faster along the inclined surface.

[0025] The second grinding assembly 3 comprises a guide cylinder 301, the guide cylinder 301 is sleeved with a rotating ring 302, the lower end of the connecting shaft 203 extends into the guide cylinder 301, the lower end of the guide cylinder 301 is provided with a mounting column 303, the side wall of the mounting column 303 is provided with a discharge port, the discharge port is communicated with the guide cylinder 301, and the lower end of the mounting column 303 is movably connected with a grinding rod 304. The second driving mechanism 6 is mounted on the baffle 103 and is used to drive the second grinding assembly 3 to rotate. The rotating ring 302 and the guide cylinder 301 are driven to rotate by the second driving mechanism 6, so that the mounting column 303 and the grinding rod 304 are driven to rotate, and the sample material broken by the first grinding assembly 2 is ground. The guide cylinder 301 of the second grinding assembly 3 can guide the directional flow of the sample, so as to avoid the loss caused by the random splashing of the sample in the cavity; when the grinding rod 304 is driven to rotate by the rotating ring 302, an annular grinding track is formed, and the constraint effect of the guide cylinder 301 is combined, so that the sample is subjected to uniform grinding force. The discharge port of the mounting column 303 can also be designed as a valve capable of accurately controlling the sample feeding amount, so as to prevent insufficient grinding caused by excessive feeding, and significantly improve the stability and consistency of fine grinding.

[0026] In the present application, the grinding rod 304 is provided with a second temperature control mechanism 7, the second temperature control mechanism 7 comprises a second pipe body 701 distributed in the grinding rod 304, a fixed pipe 702 connected to the second pipe body 701, a guide pipe 703 rotatably connected to the upper end of the fixed pipe 702, the guide pipe 703 extends to the outside of the shell 1 through the mounting column 303, the connecting shaft 203 and the mounting shaft 201 in sequence, the guide pipe 703 is rotatably connected with the mounting column 303, the connecting shaft 203 and the mounting shaft 201, and the mounting column 303 can slide along the axial direction of the guide pipe 703, that is, the mounting column 303 can slide along the guide pipe 703 in the vertical direction, and the rotating connection facilitates the rotation of the grinding rod 304 without affecting the guide pipe 703. The guide pipe 703 is connected with the water inlet and outlet of the external condenser, so that the water in the condenser is sent into the second pipe body 701 through the guide pipe 703, so as to cool the sample material during grinding. The second temperature control mechanism 7 directly cools the grinding rod 304 through an independent pipeline, can control the temperature of the grinding contact area, and avoids the damage of the heat-sensitive sample components caused by excessive local friction heat. The pipeline design of the rotating connection ensures that the rotation of the grinding rod is not disturbed, which guarantees the continuity of temperature control and does not affect the smoothness of the grinding action.

[0027] As Figures 5-6As shown in the figure, the guide tube 703 is sleeved with an inner sleeve 704, the guide tube 703 is rotationally connected with the inner sleeve 704, the inner sleeve 704 extends into the fixed tube 702 and is connected with the fixed tube 702, two water inlet and outlet pipes 705 are arranged in the inner sleeve 704 and are respectively used for cooling water to enter and flow out, when the fixed tube 702 rotates, the inner sleeve 704 rotates with the fixed tube 702, and the outer side of the water inlet and outlet pipe 705 is connected with the water inlet and outlet of the external condenser through a 360° rotary joint, so that the water inlet and outlet pipe 705 does not wind when rotating with the sleeve 704. The water inlet and outlet pipe 705 is movably connected with the inner sleeve 704, and when the height of the grinding rod 304 changes, the water inlet and outlet pipe 705 can move in the vertical direction relative to the inner sleeve 704.

[0028] In the present application, the sliding groove 305 is arranged on the bottom surface of the swivel 302, the sliding block 306 is arranged in the sliding groove 305, the threaded rod 307 is arranged in the sliding groove 305 and is rotationally connected with the sliding groove 305, the threaded rod 307 is threadedly connected with the sliding block 306, and the position of the sliding block 306 in the sliding groove 305 can be adjusted by rotating the threaded rod 307; the mounting seat 308 is arranged on both sides of the grinding rod 304, the support column 309 is rotationally connected with the mounting seat 308, the support column 309 is arranged to be inclined, and the upper end of the support column 309 is rotationally connected with the sliding block 306. The support column 309 can provide a certain thrust for the grinding rod 304, so that the sample material can be better ground, in use, the position of the sliding block 306 is adjusted, so that the inclination angle of the support column 309 is adjusted, and then the pressure of the grinding rod 304 on the sample is accurately controlled, so that the grinding of samples with different hardnesses (such as soft tissue and hard fiber samples) is adapted. The adjustable design makes the device have a wider sample application range and reduces the experimental equipment investment cost. The lower end of the inner sleeve 704 is arranged as a telescopic pipe structure, so that when the height of the grinding rod 304 changes, the inner sleeve 704 can also be lengthened or shortened, and the like Figure 5 As shown in the figure, the lower end of the guide tube 703 extends into the mounting cavity in the fixed tube 702 close to the upper end, and the end of the guide tube 703 is slidably connected with the mounting cavity, so that when the height of the grinding rod 304 changes, the guide tube 703 and the fixed tube 702 also slide relative to each other.

[0029] In a possible embodiment, the support column 309 can also be a spring telescopic rod, which can automatically compensate the contact pressure of the grinding rod 304 and the sample through elastic extension and contraction, further enhances the adaptability to the thickness change of the sample, and buffers the instantaneous impact force in the grinding process, reduces the wear of the grinding rod 304 by hard particles.

[0030] In the application, the grinding rod 304 is provided with a mounting groove 310, a spring 311 is arranged in the mounting groove 310, and the lower end of the mounting column 303 extends into the mounting groove 310 and is connected with the spring 311. Through the cooperation of the mounting groove 310, the mounting column 303 and the spring 311, the pushing force of the spring 311 is utilized during grinding, so that the grinding rod 304 can always be in contact with the grinding material. The elastic cooperation structure of the spring 311 and the mounting column 303 can also automatically compensate for the volume change during sample grinding, ensuring that the grinding rod always maintains effective contact with the sample and avoiding the phenomenon of empty grinding. The buffering effect of the spring 311 can also reduce the rigid collision between the grinding rod 304 and the bottom of the cavity, reducing the operating noise and component wear of the equipment.

[0031] The bottom of the mounting column 303 is provided with a limiting block on both sides in the mounting groove 310, and the limiting block is in sliding cooperation with the mounting groove 310.

[0032] In the application, the first temperature control mechanism 4 includes a first pipe body arranged inside the shell 1, and the first pipe body is connected with an input pipe and an output pipe extending to the outside of the shell 1 and connected with an external condenser, so as to send cooling water into the first pipe body and cool the inside of the shell 1, wherein the first pipe body is arranged on the bottom and the circumferential wall of the shell 1. The pipe body of the first temperature control mechanism 4 is distributed on the bottom and the circumferential wall of the shell 1, forming a three-dimensional temperature control area, which can maintain a constant temperature environment in the cavity in all directions. The circulating connection design with the external condenser can realize continuous heat dissipation, solve the problem of temperature accumulation during long-time grinding, and is especially suitable for large sample grinding scenes that need to be processed for a long time.

[0033] In the application, the shell 1 includes an upper cover body, an intermediate shell and a lower shell, the upper cover body is provided with a feeding port 105, the intermediate shell is movably connected with the upper cover body and the lower shell and is sealingly connected with each other, facilitating disassembly of the upper cover body, the intermediate shell and the lower shell, and the lower shell is a columnar structure with an upper opening, which can be directly disassembled after grinding. The split type shell 1 is designed to be sealingly connected, which not only ensures the airtightness of the grinding process (prevents sample pollution and volatilization), but also facilitates disassembly and cleaning of each component, effectively avoiding cross contamination between different samples. The independent disassembly structure of the lower shell makes the sample collection operation after grinding more convenient and reduces the loss during sample transfer.

[0034] In the application, the first driving mechanism 5 comprises a first motor 501, a gear one 502 and a gear two 503, the output shaft of the first motor 501 is connected with the gear one 502, the gear one 502 and the gear two 503 are engaged, the gear two 503 is provided with a gear shaft in the middle, and the gear shaft extends into the first grinding cavity 101 and is connected with the mounting shaft 201. The first motor 501 drives the gear one 502 to rotate, so that the gear two 503 engaged with the gear one 502 rotates, and then drives the gear shaft and the mounting shaft 201 to rotate, and the sample material is broken by the crushing knife 202. The gear transmission system of the first driving mechanism 5 has the characteristics of high transmission efficiency and stable operation, can accurately control the rotating speed of the crushing knife, and meets the crushing requirements of samples with different toughness. The indirect transmission design of the motor and the grinding assembly can reduce the vibration transmission and reduce the interference on the sample grinding environment.

[0035] In the application, the second driving mechanism 6 comprises a second motor, a gear ring and a gear three, the second motor is arranged in the baffle 103, the gear ring and the gear three are engaged, and the gear ring is mounted on the top surface of the rotating ring 302. The second motor drives the gear three to rotate, the gear three drives the gear ring to rotate, so that the rotating ring 302 rotates, and the rotating ring 302 drives the mounting column 303 and the grinding rod 304 to rotate when rotating, and the material falling into the bottom of the second grinding cavity 102 from the flow-through cavity and the discharge port is ground. The second driving mechanism 6 drives the rotating ring through the engagement transmission of the gear ring and the gear three, can provide stable rotating power for the rotating ring, ensures that the linear speed of the grinding rod is uniform and consistent, and improves the repeatability of fine grinding. The built-in design of the driving part in the baffle saves the space in the cavity, avoids direct contact between the sample and the driving mechanism, and improves the operation safety of the equipment.

[0036] The basic principles, main features and advantages of the application are shown and described above. It should be understood by those skilled in the art that the application is not limited by the above examples, the above examples and descriptions in the specification are only preferred examples of the application, and are not used to limit the application, various changes and improvements of the application can be made without departing from the spirit and scope of the application, and these changes and improvements all fall within the scope of the claimed application. The scope of protection of the application is defined by the appended claims and their equivalents.

Claims

1. A grinding device for biochemical laboratory comprising a housing (1), characterized in that: A first temperature control mechanism (4) is arranged in the shell (1), and a first grinding cavity (101) and a second grinding cavity (102) are arranged in the shell (1), and a first grinding assembly (2) and a second grinding assembly (3) are respectively arranged in the first grinding cavity (101) and the second grinding cavity (102); The first grinding assembly (2) comprises a mounting shaft (201), a crushing knife (202) is arranged on the mounting shaft (201), a connecting shaft (203) is connected to the lower end of the mounting shaft (201), and strip-shaped blades (204) are arranged at equal intervals in an annular manner on the outer wall of the connecting shaft (203); A baffle (103) is arranged between the first grinding cavity (101) and the second grinding cavity (102), a through hole (104) is formed in the middle of the baffle (103), the connecting shaft (203) extends into the through hole (104), a flow passage is formed between the connecting shaft (203) and the inner wall of the through hole (104), and the top surface of the baffle (103) is inclined, and the inclination is downward to one side of the through hole (104); The second grinding assembly (3) comprises a material guiding cylinder (301), a rotating ring (302) is arranged on the material guiding cylinder (301), the lower end of the connecting shaft (203) extends into the material guiding cylinder (301), an installation column (303) is arranged at the lower end of the material guiding cylinder (301), a discharge port is formed in the side wall of the installation column (303), the discharge port is in communication with the material guiding cylinder (301), and a grinding rod (304) is movably connected to the lower end of the installation column (303).

2. A grinding device for biochemical laboratory according to claim 1, characterized in that: A second temperature control mechanism (7) is arranged in the grinding rod (304), the second temperature control mechanism (7) comprises a second pipe body (701) arranged in the grinding rod (304), a fixed pipe (702) is connected to the second pipe body (701), a guide pipe (703) is rotatably connected to the upper end of the fixed pipe (702), the guide pipe (703) extends to the outside of the shell (1) through the installation column (303), the connecting shaft (203) and the mounting shaft (201) in sequence, and the guide pipe (703) is rotatably connected to the installation column (303), the connecting shaft (203) and the mounting shaft (201).

3. A grinding device for biochemical laboratory according to claim 2, characterized in that: An inner sleeve pipe (704) is rotatably arranged in the guide pipe (703), the lower end of the inner sleeve pipe (704) extends into the fixed pipe (702) and is connected to the fixed pipe (702), and two water inlet and outlet pipes (705) are arranged in the inner sleeve pipe (704); The lower end of the inner sleeve pipe (704) is arranged in an extension structure, an installation cavity is formed in the fixed pipe (702) close to the upper end, and the guide pipe (703) extends into the installation cavity and is in sliding connection with the installation cavity.

4. A grinding device for biochemical laboratory according to claim 3, characterized in that: Sliding grooves (305) are formed in the bottom surface of the rotating ring (302) on both sides, sliding blocks (306) are arranged in the sliding grooves (305), and threaded rods (307) are arranged in the sliding grooves (305) in a penetrating manner, and the threaded rods (307) are in threaded connection with the sliding blocks (306). The grinding rod (304) is provided with a mounting seat (308) on both sides, a supporting column (309) is rotatably connected to the mounting seat (308), the supporting column (309) is obliquely arranged, and the upper end of the supporting column (309) is rotatably connected with the sliding block (306).

5. A grinding device for biochemical laboratory according to claim 4, characterized in that: The grinding rod (304) is provided with a mounting groove (310), the mounting groove (310) is provided with a spring (311), and the lower end of the mounting column (303) extends into the mounting groove (310) and is connected with the spring (311).

6. The grinding device for biochemical laboratory according to claim 1, characterized in that: The first temperature control mechanism (4) comprises a first pipe body, the first pipe body is arranged in the shell (1), an input pipe and an output pipe are connected to the first pipe body, and the input pipe and the output pipe extend to the outside of the shell (1).

7. The grinding device for biochemical laboratory according to claim 1, characterized in that: The shell (1) comprises an upper cover body, a middle shell and a lower shell, the upper cover body is provided with a feeding port (105), and the middle shell is movably connected with the upper cover body and the lower shell.

8. The grinding device for biochemical laboratory according to claim 1, characterized in that: A first driving mechanism (5) is arranged at the upper end of the shell (1), and the first driving mechanism (5) is used for driving the first grinding assembly (2) to rotate. A second driving mechanism (6) is arranged on the baffle (103), and the second driving mechanism (6) is used for driving the second grinding assembly (3) to rotate.

9. A grinding device for biochemical laboratory according to claim 8, characterized in that: The first driving mechanism (5) comprises a first motor (501), a gear one (502) and a gear two (503), the output shaft of the first motor (501) is connected with the gear one (502), the gear one (502) and the gear two (503) are engaged, the gear two (503) is provided with a gear shaft in the middle, and the gear shaft extends into the first grinding cavity (101) and is connected with the mounting shaft (201).

10. A grinding device for biochemical laboratory according to claim 8, characterized in that: The second driving mechanism (6) comprises a second motor, a gear ring and a gear three, the second motor is arranged in the baffle (103), the gear ring and the gear three are engaged, and the gear ring is arranged on the top surface of the rotating ring (302).

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