Thrombectomy device

Abstract

The invention particularly relates to a thrombectomy device, which comprises a capturing bracket, one end close to the far end of the capturing bracket is connected with a far-end spring, and one end close to the near end of the capturing bracket is connected with a pushing guide wire; the capturing bracket is formed by weaving a plurality of groups of weaving wires; one end of the thrombus breaking support is connected with one end, close to the far end, of the capturing support, and the other end is connected with one end, close to the near end, of the capturing support through a flexible wire; the thrombus breaking bracket is arranged in the capturing bracket; the flexible wires are straight wires or wavy wires; when the capturing support moves towards the near end, the thrombus breaking support moves along with the capturing support, elastically deforms and cuts thrombus located in the capturing support. The flexible wire can drive the thrombus breaking support to shake, and the thrombus breaking support in the shaking state has a better cutting effect on thrombus located in the capturing support. The metal coverage rate of the end, close to the far end, of the thrombus extraction device is increased through cooperation of the capturing support and the thrombus breaking support, and small thrombus is prevented from escaping towards the far end.

Description

Technical Field

[0001] This invention relates to the field of thrombectomy stent technology, and particularly to a thrombectomy device. Background Technology

[0002] Stroke (also known as cerebrovascular accident) is a localized brain dysfunction caused by acute cerebrovascular disease. It is characterized by "four highs": high incidence, high mortality, high disability rate, and high recurrence rate. With the increasing aging of the population, its incidence continues to rise, placing a heavy burden on patients' families and the social healthcare system.

[0003] Currently, the mainstream treatment methods include thrombolysis and mechanical thrombectomy. Thrombolysis, as a traditional treatment, is limited by the 4-5 hour golden time window and carries risks such as low recanalization rates and high incidence of bleeding complications. Mechanical thrombectomy, on the other hand, directly removes the thrombus through physical means, offering advantages such as a wider range of indications, faster recanalization, and fewer drug-related complications, significantly improving patient prognosis.

[0004] Traditional thrombectomy stents still have limitations when dealing with complex thrombi such as large, heavy thrombi or hard, cardiogenic thrombi. Traditional stents mainly rely on the encapsulation and gripping action of the stent after expansion, making it difficult to effectively cut and fragment the thrombus. This single mechanical encapsulation action results in a low initial recanalization success rate, often requiring repeated thrombectomy procedures. These repeated procedures can easily cause endothelial damage, increasing the risk of intraoperative bleeding. In severe cases, large thrombi that are not completely removed may even block the aspiration catheter inlet. Summary of the Invention

[0005] To solve, or at least partially solve, the above-mentioned technical problems, the present invention provides a thrombus removal device.

[0006] This invention provides a thrombectomy device, comprising a guide wire, a capture bracket, a fragmentation bracket, and a distal spring. The distal end of the capture bracket is connected to the distal spring, and the proximal end is connected to the guide wire. The capture bracket is woven from multiple sets of braided filaments. One end of the fragmentation bracket is connected to the distal end of the capture bracket, and the other end is connected to the proximal end of the capture bracket via a flexible filament. The fragmentation bracket is disposed within the capture bracket. The flexible filament is straight or wavy. When the capture bracket moves proximally, the fragmentation bracket moves accordingly and undergoes elastic deformation, cutting the thrombus located within the capture bracket.

[0007] Optionally, each group of braided yarns is made up of multiple braided yarns; at the braiding point of two groups of braided yarns, one group of braided yarns is located in the gap between two adjacent braided yarns in the other group of braided yarns; or one braided yarn in one group of braided yarns is located in the gap between two adjacent braided yarns in the other group of braided yarns.

[0008] The present invention also provides a thrombectomy device, which includes a pusher wire, a capture bracket, a fragmentation bracket, and a distal spring. The distal end of the capture bracket is connected to the distal spring. The capture bracket is woven from multiple sets of braided wires. The fragmentation bracket is disposed within the capture bracket. One end of the pusher wire passes through the proximal end of the capture bracket into the capture bracket and is connected to the fragmentation bracket. The pusher wire drives the fragmentation bracket to move distally or proximally and cuts the thrombus located within the capture bracket.

[0009] Optionally, each group of braided yarns is made up of multiple braided yarns; at the braiding point of two groups of braided yarns, one group of braided yarns is located in the gap between two adjacent braided yarns in the other group of braided yarns; or one braided yarn in one group of braided yarns is located in the gap between two adjacent braided yarns in the other group of braided yarns.

[0010] Optionally, the push guide wire has a flexible section at one end near the puncture bracket, and the flexible section is located inside the capture bracket; the flexible section is a straight wire, a wavy wire, or a spiral wire.

[0011] Optionally, the mesh area of ​​the bolt-breaking bracket is less than or equal to the mesh area of ​​the capture bracket.

[0012] Optionally, the thrombus fragmentation support includes multiple thrombus fragmentation wires and at least two imaging rings. The multiple thrombus fragmentation wires are evenly distributed around the axis of the push guide wire. The thrombus fragmentation wires are arc-shaped wires. One of the imaging rings is located at one end of the multiple thrombus fragmentation wires near the distal end. One end of the push guide wire located inside the capture support is connected to one end of the multiple thrombus fragmentation wires near the proximal end through another imaging ring.

[0013] Optionally, the thrombus removal device also includes multiple limiting wires, which are disposed within the capture bracket and pass through the gap between any two thrombus fragmentation wires. The multiple limiting wires are arranged at intervals from the proximal end to the distal end. The axis of the limiting wire is perpendicular to the axis of the push guide wire. The distance between the limiting wire near the distal end and the limiting wire near the proximal end is less than the length of the thrombus fragmentation bracket.

[0014] Optionally, the puncture stent has multiple arc-shaped sections connected end to end.

[0015] Optionally, the capture bracket is provided with a guide wire, the axis of which is parallel to the axis of the push guide wire; the bolt breaking bracket includes multiple cutting rings and connecting wires, the multiple cutting rings are all sleeved on the guide wires and are arranged at intervals along the axis of the guide wires; adjacent cutting rings are connected by connecting wires; the cutting ring near the proximal end is connected to the end of the push guide wire located inside the capture bracket.

[0016] Optionally, the cross-sectional area of ​​the thrombus fragmentation bracket gradually increases from the direction of the distal end to the direction of the proximal end; the length of one side of the thrombus fragmentation bracket is greater than the length of the other side; one end of the push guide wire located inside the capture bracket enters the thrombus fragmentation bracket and is connected to the end of the thrombus fragmentation bracket closer to the distal end.

[0017] Optionally, the end of the capture bracket near the distal end is recessed into the capture bracket to form a protective portion; and / or, the end of the capture bracket near the proximal end is recessed into the capture bracket to form a protective portion.

[0018] Optionally, the capture bracket has multiple reduced diameter sections, which are arranged sequentially at intervals along the axis of the capture bracket and divide the internal space of the capture bracket into multiple interconnected bolt-breaking spaces; the bolt-breaking bracket is located in one bolt-breaking space; the mesh area of ​​the capture bracket gradually decreases from the direction of the near end to the direction of the far end.

[0019] Compared to existing technologies, in this embodiment, a fragmented thrombectomy stent is placed within a capture stent. One end of the fragmented stent is connected to the distal end of the capture stent, while the other end is connected to the proximal end of the capture stent via a flexible wire. During thrombectomy, the flexible wire causes the fragmented stent to vibrate. This vibration improves the thrombectomy effect on the thrombus within the capture stent and facilitates aspiration of the thrombus by the aspiration catheter. Furthermore, the combination of the capture stent and the fragmented stent increases the metal coverage of the distal end of the thrombectomy device, preventing small thrombus fragments from escaping distally. Attached Figure Description

[0020] To more clearly illustrate the embodiments of the present invention, the relevant accompanying drawings will be briefly described below. It should be understood that the drawings described below are only for illustrating some embodiments of the present invention, and those skilled in the art can obtain many other technical features and connections not mentioned herein based on these drawings.

[0021] Figure 1 This is a schematic diagram of one embodiment of a thrombectomy device of the present invention. Figure 1 ; Figure 2 This is a schematic diagram of one embodiment of a thrombectomy device of the present invention. Figure 2 ; Figure 3 This is a schematic diagram of the woven structure of a capture bracket of a thief retrieval device according to an embodiment of the present invention. Figure 1 ; Figure 4 This is a schematic diagram of the woven structure of a capture bracket of a thief retrieval device according to an embodiment of the present invention. Figure 2 ; Figure 5 This is a schematic diagram of one embodiment of a thrombectomy device of the present invention. Figure 3 ; Figure 6 This is a schematic diagram of one embodiment of a thrombectomy device of the present invention. Figure 4 ; Figure 7 This is a schematic diagram of one embodiment of a thrombectomy device of the present invention. Figure 5 ; Figure 8 This is a schematic diagram of an embodiment of a thrombus fragmentation bracket of a thrombus retrieval device according to the present invention. Figure 1 ; Figure 9 This is a schematic diagram of an embodiment of a thrombus fragmentation bracket of a thrombus retrieval device according to the present invention. Figure 2 ; Figure 10 This is a schematic diagram of one embodiment of a thrombectomy device of the present invention. Figure 6 ; Figure 11 This is a schematic diagram of an embodiment of a thrombus fragmentation bracket of a thrombus retrieval device according to the present invention. Figure 3 ; Figure 12 This is a schematic diagram of an embodiment of a thrombus fragmentation bracket of a thrombus retrieval device according to the present invention. Figure 4 ; Figure 13 This is a schematic diagram of one embodiment of a thrombectomy device of the present invention. Figure 7 ; Figure 14 This is a schematic diagram of an embodiment of a thrombus fragmentation bracket of a thrombus retrieval device according to the present invention. Figure 5 ; Figure 15 This is a schematic diagram of an embodiment of a thrombus fragmentation bracket of a thrombus retrieval device according to the present invention. Figure 6 ; Figure 16 This is a schematic diagram of one embodiment of a thrombectomy device of the present invention. Figure 8 ; Figure 17 This is a schematic diagram of an embodiment of the thief retrieval device of the present invention; Figure 18 This is a schematic diagram of one embodiment of a thrombectomy device of the present invention. Figure 9 ; Figure 19This is a schematic diagram of one embodiment of a thrombectomy device of the present invention. Figure 10 .

[0022] Explanation of reference numerals in the attached figures: 1. Push guide wire; 11. Flexible section; 2. Grasping bracket; 21. Braided wire; 22. Guide wire; 23. Protective part; 24. Diameter reduction part; 25. Grasping sub-part; 3. Clamping bracket; 31. Clamping wire; 32. Gap; 33. Arc-shaped section; 34. Arc-shaped part; 35. Cutting ring; 36. Connecting wire; 41. Distal spring; 42. Flexible wire; 43. Imaging ring; 44. Limiting wire; 5. Suction catheter; 6. Microcatheter. Detailed Implementation

[0023] To provide a more detailed understanding of the features and technical content of the embodiments of this disclosure, the implementation of the embodiments of this disclosure will be described in detail below with reference to the accompanying drawings. The accompanying drawings are for illustrative purposes only and are not intended to limit the embodiments of this disclosure. In the following technical description, for ease of explanation, several details are used to provide a full understanding of the disclosed embodiments. However, one or more embodiments may still be implemented without these details. In other cases, well-known structures and devices may be simplified in their depiction to simplify the drawings.

[0024] The terms "first," "second," etc., used in the specification, claims, and accompanying drawings of this disclosure are used to distinguish similar objects and are not necessarily used to describe a specific order or sequence. It should be understood that such data can be interchanged where appropriate for the embodiments of this disclosure described herein. Furthermore, the terms "comprising" and "having," and any variations thereof, are intended to cover non-exclusive inclusion.

[0025] In this disclosure, the terms "upper," "lower," "inner," "middle," "outer," "front," and "rear," etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. These terms are primarily for better description of the embodiments of this disclosure and their implementations, and are not intended to limit the indicated devices, elements, or components to having a specific orientation, or to require them to be constructed and operated in a specific orientation. Furthermore, some of the aforementioned terms may be used to indicate other meanings besides orientation or positional relationship; for example, the term "upper" may in some cases indicate a dependency or connection relationship. Those skilled in the art can understand the specific meaning of these terms in the embodiments of this disclosure according to the specific circumstances.

[0026] Furthermore, the terms "set up," "connect," and "fix" should be interpreted broadly. For example, "connection" can be a fixed connection, a detachable connection, or an integral structure; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, or it can be an internal connection between two devices, components, or parts. Those skilled in the art can understand the specific meaning of the above terms in the embodiments of this disclosure according to the specific circumstances.

[0027] Unless otherwise stated, the term "multiple" means two or more, and "multiple groups" means two or more groups.

[0028] It should be noted that, unless otherwise specified, the embodiments and features described in the present disclosure can be combined with each other.

[0029] In this invention, the distal end refers to the end that is far from the surgeon during surgery, and the proximal end refers to the end that is close to the surgeon during surgery.

[0030] The inventors discovered that existing thrombectomy devices can only fix thrombi, but during the thrombus removal process, thrombi are prone to getting stuck at the catheter opening and blocking it, and there is also a risk that some small thrombi may escape.

[0031] The inventors also conducted a search of existing technologies, and the following existing technologies were found: Prior art 1: Invention patent application with publication number CN118986482A; Prior art 2: Invention patent application with publication number CN115778489A; Prior art 3: Invention patent application with publication number CN119867878A.

[0032] In view of this, the inventors of the present invention provide a thrombectomy stent to solve the above-mentioned problems. Several specific embodiments of the present invention will now be described in detail with reference to the accompanying drawings.

[0033] First Embodiment The thrombectomy device mentioned in this embodiment, such as Figure 1 As shown, the thrombectomy device includes a guidewire 1, a capture stent 2, a fragmentation stent 3, and a distal spring 41. The proximal end of the distal spring 41 is connected to the distal end of the capture stent 2. The distal end of the distal spring 41 is rounded. By placing a distal spring on the thrombectomy stent, damage to the vessel wall can be prevented. The proximal end of the capture stent 2 is connected to the distal end of the guidewire 1. The capture stent 2 is a mesh-like structure woven from multiple sets of braided filaments 21, i.e., as shown... Figure 1As shown. The two ends of the capture bracket 2 are fixed, for example, by laser welding or bonding. The bolt-breaking bracket 3 is disposed within the capture bracket 2. Specifically, the distal end of the bolt-breaking bracket 3 is connected to the distal end of the capture bracket 2, the proximal end of the bolt-breaking bracket 3 is connected to one end of the flexible wire 42, and the other end of the flexible wire 42 is connected to the proximal end of the capture bracket 2.

[0034] Optional, such as Figure 1 As shown, a contrast-enhancing ring 43 is provided at the connection between the distal spring 41 and the grasping bracket 2, which strengthens the structural strength of the connection. A contrast-enhancing ring 43 is also provided at the connection between the push guide wire 1 and the grasping bracket 2, further strengthening the structural strength of the connection. Contrast enhancement via two limiting rings facilitates the surgeon's determination of the position of the grasping bracket 2.

[0035] In this embodiment, the specific structure of the flexible filament 42 is as follows: Optional, such as Figure 1 As shown, the flexible wire 42 can be a straight wire structure. The fragmentation stent 3 is connected to the capture stent 2 through the flexible wire 42 with a straight wire structure. The flexible wire 42 plays a role in connecting and fixing the fragmentation stent 3, and the flexible wire 42 facilitates the elastic deformation of the fragmentation stent 3, which is beneficial for the fragmentation stent 3 to cut the thrombus.

[0036] Optional, such as Figure 2 As shown, the flexible wire 42 can adopt a wavy wire structure. The fragmentation stent 3 is connected to the capture stent 2 through the flexible wire 42 with a wavy wire structure. The flexible wire 42 plays a role in connecting and fixing the fragmentation stent 3, and the wavy wire structure of the flexible wire 42 makes it easier for the fragmentation stent 3 to elastically deform, which is beneficial for the fragmentation stent 3 to cut the thrombus.

[0037] Either of the two optional technical solutions mentioned above can be chosen.

[0038] Optional, such as Figure 2 As shown, the distal end of the thrombus fragmentation bracket 3 is connected to the distal end of the capture bracket 2 via a flexible wire 42 with a straight wire structure. The proximal end of the thrombus fragmentation bracket 3 is connected to the proximal end of the capture bracket 2 via a flexible wire 42 with a wavy wire structure.

[0039] Optionally, the length of the capture stent 2 can be in the range of 10mm to 70mm, which can ensure that the capture stent 2 has sufficient length to capture the thrombus.

[0040] Optionally, the mesh area of ​​the fragmentation stent 3 is equal to that of the capture stent 2. The capture stent 2 with its larger mesh size facilitates the entry of thrombi into the capture stent 2, while the fragmentation stent 3 with its larger mesh size facilitates further cutting of the thrombus and prevents blockage of the catheter opening.

[0041] Optionally, the mesh area of ​​the fragmentation stent 3 is smaller than that of the capture stent 2. Through the synergistic cooperation between the capture stent 2 with its large mesh and the fragmentation stent 3 with its small mesh, the thrombus is further fragmented into multiple small thrombus fragments, preventing blockage of the catheter opening.

[0042] In this embodiment, the capture bracket 2 is a woven bracket, and the specific structural configuration of the capture bracket 2 is as follows: Optionally, not shown in the figure, the capture bracket 2 is woven from multiple sets of braided wires 21, which are made of nickel-titanium alloy. Each set of braided wires 21 includes one braided wire 21, meaning the capture bracket 2 is woven from multiple braided wires 21.

[0043] Optionally, not shown in the figure, the capture bracket 2 is woven from multiple sets of braided wires 21, which are made of nickel-titanium alloy. Each set of braided wires 21 includes multiple braided wires 21, that is, each set of braided wires 21 is made of multiple braided wires 21 wound together.

[0044] Optional, such as Figure 3 As shown, the capture bracket 2 is woven from multiple sets of braided wires 21, which are made of nickel-titanium alloy. To clarify the braiding structure of the capture bracket 2, we will use a two-set braided wire structure as an example. Each set of braided wires 21 includes two wires 21, meaning each set is formed by winding two wires 21 together. At the braiding point of the two sets of wires, the two wires 21 of one set are located in the gap between the two wires 21 of the other set. This arrangement increases the radial support force of the capture bracket 2.

[0045] Optional, such as Figure 4 As shown, the capture bracket 2 is woven from multiple sets of braided wires 21, which are made of nickel-titanium alloy. To clarify the braiding structure of the capture bracket 2, we will use a two-set braided wire structure as an example. Each set of braided wires 21 includes two wires 21, meaning each set is formed by winding two wires 21 together. At the braiding point of the two sets of wires, one wire 21 from one set is located in the gap between two wires 21 from the other set, and vice versa. This arrangement increases the radial support force of the capture bracket 2.

[0046] You may choose any one of the four technical solutions mentioned above.

[0047] The exemplary usage process of the thrombectomy device disclosed in this embodiment is as follows: like Figures 1 to 5As shown, firstly, the aspiration catheter 5 is inserted into the blood vessel, with the catheter opening of the aspiration catheter 5 located proximal to the thrombus. Then, the microcatheter 6 is placed within the aspiration catheter 5, with its distal end penetrating the thrombus to its distal end. Next, the thrombectomy device is placed within the microcatheter 6. The guidewire 1 is driven to move distally, releasing the capture stent 2 and the fragmentation stent 3 into the blood vessel. At this point, both the capture stent 2 and the fragmentation stent 3 are located distal to the thrombus. After release, the capture stent 2 and the fragmentation stent 3 are in a non-compressible state and are in contact with the inner wall of the blood vessel. The microcatheter 6 is driven proximally and then retracted into the aspiration catheter 5. Then, the guidewire 1 drives the capture stent 2 and the fragmentation stent 3 proximally. The capture stent 2 first engages with and captures the thrombus, and the thrombus moves proximally as the capture stent 2 moves. When a large thrombus blocks the opening of the aspiration catheter 5, the guidewire 1 continues to move proximally, allowing the thrombus to enter the capture stent 2. The fragmentation stent 3 then performs a secondary cut on the thrombus within the capture stent 2. During the proximal movement of the flexible wire 42, it vibrates, causing the fragmentation stent 3 to vibrate as well. As the flexible wire 42 undergoes elastic deformation, the outer diameter and length of the fragmentation stent decrease, resulting in better cutting of the thrombus within the capture stent 2 by the vibrating fragmentation stent 3. The combined action of the capture stent 2 and the fragmentation stent 3 cuts the large thrombus into smaller pieces, which are then aspirated to the outside via the aspiration catheter 5. This combination also increases the metal coverage of the distal end of the thrombectomy device, preventing smaller thrombus pieces from escaping distally.

[0048] Compared to existing technologies, in this embodiment, a fragmented thrombectomy stent is placed within a capture stent. One end of the fragmented stent is connected to the distal end of the capture stent, while the other end is connected to the proximal end of the capture stent via a flexible wire. During thrombectomy, the flexible wire causes the fragmented stent to vibrate. This vibration improves the thrombectomy effect on the thrombus within the capture stent and facilitates aspiration of the thrombus by the aspiration catheter. Furthermore, the combination of the capture stent and the fragmented stent increases the metal coverage of the distal end of the thrombectomy device, preventing small thrombus fragments from escaping distally.

[0049] Second Embodiment This embodiment also proposes a thrombectomy device. The second embodiment is a parallel technical solution to the first embodiment, and the difference between the second embodiment and the first embodiment is that: like Figure 6As shown, the thrombectomy device includes a guide wire 1, a capture bracket 2, a fragmentation bracket 3, and a distal spring 41. The proximal end of the distal spring 41 is connected to the distal end of the capture bracket 2. The distal end of the distal spring 41 is rounded. A contrast-enhancing ring 43 is provided at the connection between the distal spring 41 and the capture bracket 2 to strengthen the structural strength of the connection. A contrast-enhancing ring 43 is also provided at the proximal end of the capture bracket 2 to strengthen the structural strength of that proximal end. Contrast enhancement is achieved through two limiting rings, facilitating the surgeon's determination of the capture bracket 2's position. The capture bracket 2 is a mesh-like structure woven from multiple sets of braided wires 21, i.e.... Figure 6 As shown. The thrombus fragmentation support 3 is disposed within the capture support 2. Specifically, the distal end of the push guide wire 1 passes through the imaging ring 43 located near the proximal end of the capture support 2 into the capture support 2. The end of the push guide wire 1 located within the capture support 2 is connected to the proximal end of the thrombus fragmentation support 3. In this embodiment, the distal end of the push guide wire 1 has a flexible segment 11, which can be considered as the end of the push guide wire 1 near the thrombus fragmentation support 3 having a flexible segment 11. The specific structure of the flexible segment 11 is as follows: Optional, such as Figure 6 As shown, the flexible section 11 is located inside the capture bracket 2, and the flexible section 11 adopts a straight wire structure.

[0050] Optional, such as Figure 7 As shown, the flexible section 11 is located inside the capture bracket 2, and the flexible section 11 adopts a corrugated wire structure.

[0051] Either of the two optional technical solutions mentioned above can be chosen.

[0052] In this embodiment, the specific structural configuration of the thrombus stent 3 is as follows: Optionally, the thrombus stent 3 can be a single laser-engraved stent, a single braided stent, a laser-engraved composite stent, or a braided composite stent.

[0053] Optionally, the thrombus stent 3 is made of nickel-titanium alloy.

[0054] Optional, such as Figure 7 , Figure 8 As shown, a contrast ring 43 is provided at the distal end of the fragmented stent 3 to enhance the structural strength of the distal end of the fragmented stent 3. A contrast ring 43 is also provided at the connection between the proximal end of the fragmented stent 3 and the flexible segment 11 to enhance the structural strength of the connection between the guidewire 1 and the fragmented stent 3. The contrast rings, along with the two limiting rings, facilitate the surgeon in determining the position of the fragmented stent 3.

[0055] The exemplary usage process of the thrombectomy device disclosed in this embodiment is as follows: like Figures 5 to 8 As shown, firstly, the aspiration catheter 5 is inserted into the blood vessel, with the catheter opening of the aspiration catheter 5 located proximal to the thrombus. Then, the microcatheter 6 is placed within the aspiration catheter 5, with its distal end penetrating the thrombus to its distal end. Next, the thrombectomy device is placed within the microcatheter 6. The guidewire 1 is driven to move distally, releasing the capture stent 2 and the fragmented stent 3 into the blood vessel. At this point, both the capture stent 2 and the fragmented stent 3 are located distal to the thrombus. After release, the capture stent 2 and the fragmented stent 3 are in a non-compressible state and in contact with the vessel wall. The microcatheter 6 is driven proximally and retracted into the aspiration catheter 5. Then, the guidewire 1 drives the fragmented stent 3 proximally. As the fragmented stent 3 moves, its proximal end contacts the proximal end of the capture stent 2, causing the fragmented stent 3 to move proximally along with the capture stent 2. The capturing stent 2 first engages with and captures the thrombus, which then moves proximally as the capturing stent 2 moves. When a large thrombus blocks the opening of the aspiration catheter 5, the push guidewire 1 is driven to move distally, and the fragmentation stent 3 cuts the thrombus within the capturing stent 2 once. The push guidewire 1 is then driven to move proximally, and the fragmentation stent 3 cuts the thrombus within the capturing stent 2 again, thus improving the cutting effect of the fragmentation stent. The flexible wire 42 vibrates during its movement distally or proximally, causing the fragmentation stent 3 to vibrate as well, further enhancing the cutting effect of the fragmentation stent within the capturing stent 2. Through the cooperation of the capturing stent 2 and the fragmentation stent 3, large thrombi are cut into smaller pieces, which are then aspirated to the outside through the aspiration catheter 5, preventing blockage of the aspiration catheter 5's opening.

[0056] Compared to existing technologies, in this embodiment, by placing the fragmented thrombus stent within the capture stent and driving it distally or proximally using a guidewire, a large thrombus within the capture stent is broken into multiple smaller pieces, thus avoiding blockage of the aspiration catheter 5's opening. During thrombus retrieval, the flexible wire causes the fragmented thrombus stent to vibrate. The vibrating stent provides better cutting of the thrombus within the capture stent and facilitates aspiration of the thrombus by the aspiration catheter.

[0057] Third Embodiment This embodiment also proposes a thrombus removal device. The third embodiment is a further improvement based on the first or second embodiment. The main improvement lies in the structure of the thrombus fragmentation support 3, which is specifically as follows: Optional, such as Figure 9As shown, the fragmented stent 3 includes multiple fragmented wires 31 and two contrast-enhancing rings 43. One contrast-enhancing ring 43 is located at the distal end of the multiple fragmented wires 31, which strengthens the structural strength of the distal end of the fragmented stent 3. The proximal ends of the multiple fragmented wires 31 are all connected to the flexible segment 11 located within the capture stent 2. The other contrast-enhancing ring 43 is located at the connection between the proximal end of the multiple fragmented wires 31 and the flexible segment 11, which strengthens the structural strength at the connection between the guide wire 1 and the fragmented stent 3. The multiple fragmented wires 31 are all arc-shaped wires, as shown in the figure. The multiple fragmented wires 31 are evenly distributed around the axis of the guide wire 1. A gap 32 is formed between any two fragmented wires 31. This arrangement can control the cutting effect of the fragmented stent on large thrombi and prevent the escape of small thrombi.

[0058] Optional, such as Figure 3 , Figure 9 , Figure 10 As shown, based on the above technical solution, the thrombectomy device also includes multiple limiting wires 44. For ease of explanation, two limiting wires 44 are used, both of which are installed within the capture bracket 2. The two limiting wires 44 are spaced apart from the proximal end towards the distal end. Both ends of the limiting wires 44 are connected to the braided wires 21 of the capture bracket 2. The axis of the limiting wires 44 is perpendicular to the axis of the push guide wire 1. Both limiting wires 44 pass through the gap 32 between any two fragmentation wires 31. The distance between the limiting wire 44 near the distal end and the limiting wire 44 near the proximal end is less than the length of the fragmentation bracket 3. By controlling the movement distance of the fragmentation bracket through the limiting wires, the cutting effect of the fragmentation bracket on large thrombi can be further controlled.

[0059] Optional, such as Figure 11 As shown, based on the optional technical solution of the thrombectomy stent 3 including multiple thrombectomy wires 31 and two contrast-enhancing rings 43, at least one point on each thrombectomy wire 31 is concave towards the axis of the guidewire 1, and the thrombectomy wire 31 has at least two arc-shaped segments 33. When the multiple thrombectomy wires 31 are evenly distributed around the axis of the guidewire 1, the arc-shaped segments 33 at the same position on the multiple thrombectomy wires 31 together form an arc-shaped portion 34. When the multiple arc-shaped portions 34 are connected end to end, the multiple arc-shaped portions 34 together form the thrombectomy stent 3. A gap 32 is formed between any two thrombectomy wires 31. This setting can control the cutting effect of the thrombectomy stent on large thrombi and prevent the escape of small thrombi.

[0060] Optional, such as Figure 10 , Figure 11As shown, based on the above technical solution, the thrombectomy device also includes multiple limiting wires 44. For ease of explanation, there are two limiting wires 44, both of which are installed inside the capture bracket 2. The two limiting wires 44 are spaced apart from the proximal end to the distal end. Both ends of the limiting wires 44 are connected to the braided wires 21 of the capture bracket 2. The axis of the limiting wires 44 is perpendicular to the axis of the push guide wire 1. Both limiting wires 44 pass through the gap 32 between any two fragmentation wires 31. The distance between the limiting wire 44 near the distal end and the limiting wire 44 near the proximal end is less than the length of the fragmentation bracket 3. During the movement of the fragmentation bracket, a point on the fragmentation wire will contact the limiting wire, intensifying the shaking effect of the fragmentation bracket and using it to cut large thrombi.

[0061] Optional, such as Figure 12 As shown, when the fragmentation stent 3 is a braided stent, at least one position on the fragmentation stent 3 is recessed towards the axis of the guidewire 1, and the fragmentation stent 3 has at least two arc-shaped portions 34, which are connected end to end. This configuration allows the fragmentation stent to cut the thrombus in one operation, producing a two-stage cutting effect.

[0062] You may choose any one of the five optional technical solutions mentioned above.

[0063] Fourth embodiment This embodiment also proposes a thrombus removal device. The fourth embodiment is a parallel technical solution to the third embodiment. The difference between the fourth embodiment and the third embodiment is that: like Figure 13As shown, the thrombus removal device also includes a guide wire 22, which is disposed within the capture bracket 2. The guide wire 22 is coaxial with the push guide wire 1, or the axis of the guide wire 22 is parallel to the axis of the push guide wire 1. One end of the guide wire 22 is connected to the distal end of the capture bracket 2, and the other end of the guide wire 22 is connected to the proximal end of the capture bracket 2. The thrombus fragmentation bracket 3 includes multiple cutting rings 35 and multiple connecting wires 36. The cutting rings 35 are made of nickel-titanium alloy wire wound into a ring structure. The multiple cutting rings 35 are all located within the capture bracket 2, and are all sleeved on the guide wire 22. The multiple cutting rings 35 are arranged sequentially and at intervals along the axis of the guide wire 22. Adjacent cutting rings 35 are connected by multiple connecting wires 36. The multiple connecting wires 36 are evenly distributed around the axis of the push guide wire 1. One end of each connecting wire 36 is connected to a cutting ring 35, and the other end of each connecting wire 36 is connected to another cutting ring 35. The distance between the cutting ring 35 near the distal end and the cutting ring 35 near the proximal end is less than the length of the capture stent 2. A flexible segment 11 is provided at the distal end of the guide wire 1, located within the capture stent 2. The flexible segment 11 has a helical wire structure and is sleeved on the guide wire 22. The cutting ring 35 near the proximal end is connected to one end of the flexible segment 11. This arrangement allows control over the cutting effect of the fragmentation stent on large thrombi.

[0064] Fifth embodiment This embodiment also proposes a thrombus removal device. The fifth embodiment is a parallel technical solution to the third embodiment. The difference between the fifth embodiment and the third embodiment is that: Optional, such as Figure 3 , Figures 13 to 15 As shown, the fragmented stent 3 has a conical structure. Specifically, the fragmented stent 3 is woven from multiple braided wires 21. A contrast-enhancing ring 43 is provided at the distal end of the fragmented stent 3, which fixes the distal end of the fragmented stent 3, thereby strengthening the structural strength of the distal end of the grasping stent 2. A cutting ring 35 is provided at the proximal end of the fragmented stent 3, which seals the proximal end of the fragmented stent 3, further increasing the cutting effect of the fragmented stent 3. The cross-sectional area of ​​the fragmented stent 3 gradually increases from the distal end to the proximal end, reaching 1 / 4 to 3 / 4 of the outer diameter of the grasping stent 2, and the length of one side of the fragmented stent 3 is greater than the length of the other side, which facilitates the entry of thrombi into the fragmented stent 3 and facilitates the fragmented stent 3 in cutting the thrombi. The end of the guide wire 1 located inside the grasping stent 2 enters the fragmented stent 3 and connects to the distal end of the fragmented stent 3.

[0065] Optional, such as Figure 15As shown, based on the above technical solution, a flexible segment 11 is provided at the distal end of the guidewire 1. The flexible segment 11 is located inside the capture stent 2 and adopts a corrugated wire structure. The flexible segment 11 enters the fragmentation stent 3 and connects to the distal end of the fragmentation stent 3. By driving the fragmentation stent 3 proximally through the guidewire 1, it is not only easier for the thrombus to enter the conical fragmentation stent, but the corrugated wire flexible segment 11 also causes the fragmentation stent to vibrate during the proximal movement, further increasing the fragmentation stent's cutting effect on the thrombus.

[0066] Sixth Embodiment This embodiment also proposes a thrombus removal device. The sixth embodiment is a further improvement based on any one of the first to fifth embodiments. The main improvement lies in the structure of the capture bracket 2, as follows: Optional, such as Figure 3 , Figure 16 , Figure 17 As shown, when multiple sets of braided filaments 21 are braided into the distal end of the grasping stent 2, the multiple sets of braided filaments 21 are braided into the interior of the grasping stent 2 to form a protective portion 23, that is, the distal end of the grasping stent 2 is recessed into the grasping stent 2 to form the protective portion 23. The cross-sectional area of ​​the protective portion 23 gradually decreases from the distal end to the proximal end. The distal end of the grasping stent 2 is fixed by a contrast ring 43, and the limiting ring is located inside the grasping stent 2. By setting the protective portion 23 at the distal end of the grasping stent 2, damage to the inner wall of the blood vessel can be prevented from the grasping stent 2.

[0067] Optional, such as Figure 3 , Figure 16 , Figure 17 As shown, when multiple sets of braided filaments 21 are braided into the proximal end of the grasping stent 2, the multiple sets of braided filaments 21 are braided into the interior of the grasping stent 2 to form a protective portion 23, that is, the proximal end of the grasping stent 2 is recessed into the grasping stent 2 to form the protective portion 23. The cross-sectional area of ​​the protective portion 23 gradually decreases from the proximal direction to the distal direction. The proximal end of the grasping stent 2 is fixed by a contrast ring 43, and the limiting ring is located inside the protective portion 23. By setting the protective portion 23 at the proximal end of the grasping stent 2, damage to the inner wall of the blood vessel can be prevented from the grasping stent 2.

[0068] Optionally, the two alternative technical solutions mentioned above can be combined.

[0069] Seventh Embodiment This embodiment also proposes a thrombus removal device. The seventh embodiment is a further improvement based on any one of the first to sixth embodiments. The main improvement lies in the structure of the capture bracket 2, as follows: Optional, such as Figure 18 As shown, the capture bracket 2 has multiple reduced-diameter sections 24, which are arranged sequentially and at intervals along the axis of the capture bracket 2. The inner diameter of each reduced-diameter section 24 is smaller than the inner diameter of the capture bracket 2. These multiple reduced-diameter sections 24 divide the capture bracket 2 into multiple capture sub-sections 25. The internal space of each capture sub-section 25 can be considered as a fragmentation space, and adjacent fragmentation spaces are interconnected. In other words, the multiple reduced-diameter sections 24 divide the space within the capture bracket 2 into multiple interconnected fragmentation spaces. The length of the fragmentation bracket 3 is less than the length of the capture sub-section 25, and the maximum outer diameter of the fragmentation bracket 3 is greater than the minimum inner diameter of the reduced-diameter sections 24. The fragmentation bracket 3 is disposed within any one of the multiple fragmentation spaces. The proximal end of the fragmentation bracket 3 is connected to the flexible segment 11 of the pusher guide wire 1, and the flexible segment 11 has a corrugated wire structure. The weaving density of the reduced-diameter sections 24 is greater than the weaving density of the capture sub-sections 25, and the mesh area of ​​the reduced-diameter sections 24 is smaller than the mesh area of ​​the capture sub-sections 25. This design prevents the shredded blood clot from escaping through the constriction 24. For example, as... Figure 18 As shown, a large thrombus is located within the grasping section 25 near the proximal end, and the fragmentation stent 3 is also located within the grasping section 25 near the proximal end. When cutting the large thrombus, the guide wire 1 is driven to move distally. Utilizing the difference between the maximum outer diameter of the fragmentation stent 3 and the minimum inner diameter of the narrowed section 24, the narrowed section 24 compresses the fragmentation stent 3, assisting in cutting the thrombus. Through the coordinated action of the fragmentation stent 3 and the narrowed section 24, the cutting effect of the fragmentation stent on the thrombus is improved.

[0070] Optional, such as Figure 19 As shown, based on the above scheme, the mesh area of ​​the same capturing sub-section 25 is the same. The mesh area of ​​the capturing sub-section 25 near the proximal end is the largest, and the mesh area of ​​the capturing sub-section 25 near the distal end is the smallest. That is, from the direction of the proximal end to the direction of the distal end, the mesh area of ​​multiple capturing sub-sections 25 gradually decreases, and the weaving density gradually increases. This arrangement can prevent some small thrombi from escaping.

[0071] The foregoing description and accompanying drawings fully illustrate embodiments of the invention to enable those skilled in the art to practice them. Other embodiments may include structural and other changes. The embodiments represent only possible variations. Individual components and functions are optional unless explicitly required, and the order of operation may vary. Some portions and features of some embodiments may be included or substituted for portions and features of other embodiments. Embodiments of the invention are not limited to the structures described above and shown in the accompanying drawings, and various modifications and changes may be made without departing from their scope. The scope of the invention is limited only by the appended claims.

Claims

1. A thrombus removal device, characterized in that, include: The capture bracket has one end near the distal end connected to a distal spring and the other end near the proximal end connected to a push guide wire. The capture frame is woven from multiple sets of braided wires; The bolt-breaking bracket has one end connected to the distal end of the capture bracket, and the other end connected to the proximal end of the capture bracket via a flexible wire; the bolt-breaking bracket is located inside the capture bracket; the flexible wire is a straight wire or a wavy wire. The capture bracket moves proximally, and the thrombus fragmentation bracket moves accordingly and undergoes elastic deformation, cutting the thrombus located within the capture bracket.

2. The thrombectomy device according to claim 1, characterized in that, Each group of braided yarns is made up of multiple braided yarns wound together; At the weaving point of two sets of braided yarns, one set of braided yarns is located in the gap between two adjacent braided yarns in the other set of braided yarns; or one braided yarn in one set of braided yarns is located in the gap between two adjacent braided yarns in the other set of braided yarns.

3. A thrombus removal device, characterized in that, include: The capture bracket has one end near the distal end connected to a distal spring; the capture bracket is woven from multiple sets of braided wires. A bolt-breaking bracket is installed inside the capture bracket; The guide wire is pushed through one end of the capture bracket near the proximal end into the capture bracket and connected to the puncture bracket. The guide wire is pushed to drive the fragmentation stent to move distally or proximally and to cut the thrombus located within the capture stent.

4. The thrombectomy device according to claim 3, characterized in that, Each group of braided yarns is made up of multiple braided yarns wound together; At the weaving point of two sets of braided yarns, one set of braided yarns is located in the gap between two adjacent braided yarns in the other set of braided yarns; or one braided yarn in one set of braided yarns is located in the gap between two adjacent braided yarns in the other set of braided yarns.

5. The thrombectomy device according to claim 3, characterized in that, The push guide wire has a flexible section at one end near the thrombus breakage bracket, and the flexible section is located inside the capture bracket. The flexible section is a straight filament, a wavy filament, or a spiral filament.

6. The thrombectomy device according to claim 3, characterized in that, The mesh area of ​​the bolt-breaking bracket is less than or equal to the mesh area of ​​the capture bracket.

7. The thrombectomy device according to claim 3, characterized in that, The fragmented stent includes: Multiple broken plug wires are evenly distributed around the axis of the push guide wire; the broken plug wires are arc-shaped wires; At least two developing rings, one of which is located at the distal end of a plurality of broken tether wires; the end of the push guide wire located within the capture bracket is connected to the proximal end of the plurality of broken tether wires via the other developing ring.

8. The thrombectomy device according to claim 7, characterized in that, Also includes: Multiple limiting wires are installed inside the capture bracket, and each wire passes through the gap between any two break-lock wires. The multiple limiting wires are arranged at intervals from the proximal end to the distal end. The axis of the limiting wire is perpendicular to the axis of the push guide wire. The distance between the limiting wire near the distal end and the limiting wire near the proximal end is less than the length of the break-lock bracket.

9. The thrombectomy device according to claim 3, characterized in that, The puncture stent has multiple arc-shaped sections connected end to end.

10. The thrombectomy device according to claim 3, characterized in that, The capture bracket is equipped with a guide wire, the axis of which is parallel to the axis of the pushing guide wire; the thrombus breaking bracket includes: Multiple cutting rings are fitted onto the guide wire and are spaced apart sequentially along the axis of the guide wire; adjacent cutting rings are connected by a connecting wire; the cutting ring near the proximal end is connected to the end of the push guide wire located inside the capture bracket.

11. The thrombectomy device according to claim 3, characterized in that, The cross-sectional area of ​​the thrombus fragmentation stent gradually increases from the distal end to the proximal end; the length of one side of the thrombus fragmentation stent is greater than the length of the other side. The pusher wire is inserted into the fragmentation bracket at one end within the capture bracket and connected to the distal end of the fragmentation bracket.

12. The thrombectomy device according to claim 3, characterized in that, The end of the capture bracket near the distal end is recessed into the capture bracket to form a protective portion; and / or, the end of the capture bracket near the proximal end is recessed into the capture bracket to form a protective portion.

13. The thrombectomy device according to claim 3, characterized in that, The capture bracket has multiple reduced diameter sections, which are arranged sequentially at intervals along the axis of the capture bracket and divide the internal space of the capture bracket into multiple interconnected break-bolt spaces; the break-bolt bracket is located in one break-bolt space. The mesh area of ​​the capture bracket gradually decreases from the near end to the far end.

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