Pesticide composition and application thereof

Abstract

The invention belongs to the technical field of pesticide sterilization, and discloses a pesticide composition and application thereof.The pesticide composition comprises an active ingredient A and an active ingredient B. The active ingredient A is Cyclobutrifluram, the active ingredient B is any one of tetramycin, validamycin, phenazino-1-carboxylic acid or kasugamycin, and the active ingredient B is one of cyclobutrifluram, validamycin, phenazino-1-carboxylic acid and kasugamycin. The mass ratio of the active component A to the active component B is (1: 48)-(1: 52). The pesticide composition disclosed by the invention has an obvious synergistic effect on pathogenic bacteria and is harmless to target crops and other organisms.

Description

[0001] This invention application is a divisional application of application number 202311635637.3, filed on December 1, 2023, entitled "A pesticide composition and its use". Technical Field

[0002] This invention belongs to the field of pesticide sterilization technology and discloses a pesticide composition and its use. Background Technology

[0003] The prolonged and extensive use of chemical fungicides has led to increased pathogen resistance and increasingly serious pesticide residue exceeding standards. From the perspective of aligning with my country's green agricultural development, biological agents, due to their low toxicity and residue, good environmental compatibility, and the likelihood of pests developing resistance, play a positive role in reducing chemical pesticide use and ensuring the quality and safety of agricultural products and the ecological environment. However, the number of registered biological agents in my country is currently limited, and in actual production, the control effect of farmers using biological agents alone is not very good, hindering the application and promotion of biological agents.

[0004] Chemical agents are the primary means of controlling plant diseases. Because biological agents and chemical agents have different mechanisms of action against pathogens, their synergistic use has greater potential for reducing chemical agent dosage and enhancing efficacy. However, due to significant differences in pharmacological effects between biological and chemical pesticides, strict requirements are placed on application time, temperature, method, and mixing techniques. Therefore, the applicant conducted extensive experimental research on the combination of Cyclobutrifluram with any one of tetracycline, jinggangmycin, shenqinmycin, or kasugamycin to explore the optimal quality ratio of the compound combination, providing an alternative agent for the current control of plant diseases caused by Fusarium fungi with reduced chemical agent dosage and enhanced efficacy. Summary of the Invention

[0005] Based on the above problems, the purpose of this invention is to provide a pesticide composition with synergistic effects, especially with high control efficacy against wheat scab, and with reduced dosage and ability to slow down the development of pathogen resistance.

[0006] Another object of the present invention is to provide the use of the pesticide composition or its formulation for the prevention and control of plant diseases;

[0007] Another object of the present invention is the application of the pesticide composition and its formulation in the prevention and control of wheat scab.

[0008] To achieve the above objectives, the present invention adopts the following technical solution: a pesticide composition and its use, wherein the pesticide composition comprises active ingredient A and active ingredient B, wherein active ingredient A is Cyclobutrifluram, and active ingredient B is any one of tetracycline, jinggangmycin, shenqinmycin, or kasugamycin.

[0009] Furthermore, the mass ratio of active ingredient A to active ingredient B is 1:48 to 1:52.

[0010] Furthermore, the active ingredient B is tetracycline, and the mass ratio of active ingredient A to active ingredient B is 1:32 to 48:1;

[0011] The active ingredient B is jinggangmycin, and the mass ratio of active ingredient A to active ingredient B is 1:24 to 52:1;

[0012] The active ingredient B is shenqinmycin, and the mass ratio of active ingredient A to active ingredient B is 1:30 to 20:1;

[0013] The active ingredient B is kasugamycin, and the mass ratio of active ingredient A to active ingredient B is 1:40 to 20:1.

[0014] Furthermore, the active ingredient B is tetracycline, and the mass ratio of active ingredient A to active ingredient B is 1:24 to 32:1;

[0015] The active ingredient B is jinggangmycin, and the mass ratio of active ingredient A to active ingredient B is 1:12 to 48:1;

[0016] The active ingredient B is shenqinmycin, and the mass ratio of active ingredient A to active ingredient B is 1:20 to 10:1;

[0017] The active ingredient B is kasugamycin, and the mass ratio of active ingredient A to active ingredient B is 1:30 to 10:1.

[0018] Furthermore, based on the total weight of the pesticide composition as 100%, the total weight of active ingredient A and active ingredient B accounts for 0.1% to 80% of the total weight of the fungicide composition.

[0019] Furthermore, the bactericidal composition, in addition to the active ingredient, also contains pesticide-permitted auxiliary ingredients, which are selected from one or more of the following: wetting agents, dispersants, emulsifiers, thickeners, disintegrants, antifreeze agents, defoamers, solvents, preservatives, stabilizers, synergists, binders, fillers, or carriers.

[0020] Further, the wetting agent is selected from one or more of alkylbenzene sulfonates, alkylnaphthalene sulfonates, lignin sulfonates, sodium dodecyl sulfate, sodium dioctyl succinate sulfonate, α-olefin sulfonates, alkylphenol polyoxyethylene ethers, castor oil polyoxyethylene ethers, alkylphenol ethoxylates, fatty alcohol ethoxylates, sodium fatty alcohol polyoxyethylene ether sulfate, silkworm excrement, soapberry powder, soapberry powder, SOPA, detergents, emulsifiers 2000 series, and wetting and penetrating agents F; and / or

[0021] Further, the dispersant is selected from one or more of the following: lignin sulfonate, alkyl naphthalene sulfonate formaldehyde condensate, naphthalene sulfonate, tristyrylphenol ethoxylate phosphate, fatty alcohol ethoxylate, alkylphenol polyoxyethylene ether, alkylphenol polyoxyethylene ether methyl ether condensate sulfate, fatty amine polyoxyethylene ether, glycerol fatty acid ester polyoxyethylene ether, polycarboxylates, polyacrylic acids, phosphates, EO-PO block copolymers, and EO-PO graft copolymers; and / or

[0022] Further, the emulsifier is selected from one or more of the following: calcium dodecylbenzenesulfonate, alkylphenol formaldehyde resin polyoxyethylene ether, phenethylphenol polyoxyethylene polyoxypropylene ether, fatty alcohol ethylene oxide-propylene oxide copolymer, styrene-phenol polyoxyethylene ether, castor oil polyoxyethylene ether, and alkylphenol ether phosphate; and / or

[0023] Furthermore, the thickener is selected from one or more of xanthan gum, organobentonite, gum arabic, sodium alginate, magnesium aluminum silicate, carboxymethyl cellulose, and silica; and / or

[0024] Further, the disintegrant is selected from one or more of sodium sulfate, ammonium sulfate, aluminum chloride, sodium chloride, ammonium chloride, bentonite, glucose, sucrose, starch, cellulose, urea, sodium carbonate, sodium bicarbonate, citric acid, and tartaric acid; and / or

[0025] Furthermore, the antifreeze is selected from one or more of alcohols, alcohol ethers, chlorinated hydrocarbons, and inorganic salts; and / or

[0026] Furthermore, the defoamer is selected from C 10 -C 20 Saturated fatty acid compounds, silicone oil, silicone compounds, C8-C 10 One or more of the fatty alcohols; and / or

[0027] Further, the solvent is selected from one or more of benzene, toluene, xylene, mesitylene, methanol, ethanol, isopropanol, n-butanol, dimethyl sulfoxide, dimethylformamide, cyclohexanone, hydrocarbon carbonates, diesel oil, solvent oil, vegetable oil (soybean oil, corn oil, rapeseed oil, palm oil, etc.), vegetable oil derivatives, and water; and / or

[0028] Further, the preservative is selected from one or more of propionic acid, sodium propionate, sorbic acid, sodium sorbate, potassium sorbate, benzoic acid, sodium benzoate, sodium p-hydroxybenzoate, methyl p-hydroxybenzoate, Kathon, and 1,2-benzisothiazolin-3-one; and / or

[0029] Further, the stabilizer is selected from one or more of the following: disodium hydrogen phosphate, oxalic acid, succinic acid, adipic acid, borax, 2,6-di-tert-butyl-p-methylphenol, triethanolamine oleate, epoxidized vegetable oil, kaolin, diatomaceous earth, bentonite, attapulgite, silica, talc, montmorillonite, and starch; and / or

[0030] Furthermore, the synergist is selected from synergistic phosphorus, synergistic ether; and / or

[0031] Furthermore, the carrier is selected from one or more of the following: ammonium salts, ground natural minerals, ground artificial minerals, silicates, resins, waxes, solid fertilizers, water, organic solvents, mineral oils, vegetable oils, and vegetable oil derivatives.

[0032] Furthermore, the pesticide composition can be prepared into a pesticide-acceptable formulation, wherein the formulation is a solid or liquid formulation.

[0033] Furthermore, the solid dosage form is granules, strips, wettable powder, oil-dispersible powder, emulsion powder, water-dispersible granules, emulsion granules, water-dispersible tablets, soluble powder, soluble tablets, or soluble granules; the liquid dosage form is a soluble solvent, soluble gel, oil, film-spreading oil, emulsion, latex, dispersible liquid, ointment, water emulsion, oil emulsion, microemulsion, lipid, suspension, microcapsule suspension, oil suspension, dispersible oil suspension, or suspension emulsion.

[0034] The present invention also discloses the use of the pesticide composition described above for the prevention and control of plant diseases.

[0035] Furthermore, the plant disease mentioned is wheat scab.

[0036] The beneficial effects of this invention are as follows:

[0037] 1) The bactericidal composition of the present invention has a significant synergistic effect on plant pathogens within a certain range, and its preventive effect is significant;

[0038] 2) The bactericidal combination of the present invention can effectively reduce the dosage of pesticides, reduce pesticide residues, and is safe for the environment. Detailed Implementation

[0039] To make the objectives, technical solutions, and advantages of this invention clearer and more concise, the invention is described using the following specific embodiments. However, this invention is by no means limited to these embodiments. The embodiments described below are merely preferred embodiments of this invention and are used to describe the invention; they should not be construed as limiting the scope of the invention.

[0040] Preparation Example 1: 12% Cyclobutrifluram·Tetramycin Soluble Solution (3:1)

[0041] Formula composition: 9% Cyclobutrifluram, 3% Tetramycin, 15% Ethanol, 12% Fatty Alcohol Polyoxyethylene Ether, 15% Cyclohexanone, DMF to make up to 100%.

[0042] Preparation method: Add the active ingredients to the solvent according to the formula ratio, and add surfactants and other functional additives. Stir and mix evenly in a stirring mixing tank to obtain the soluble product.

[0043] Preparation Example 2: 14% Cyclobutrifluram·Tetramycin Suspension (6:1)

[0044] Formula composition: 12% Cyclobutrifluram, 2% Tetramycin, 2% Sodium Dodecyl Sulfate, 2% Styrene-phenol Polyoxyethylene Ether Phosphate, 2% Naphthalene Sulfonate Formaldehyde Condensate, 0.25% Xanthan Gum, 1% Magnesium Aluminum Silicate, 4% Propylene Glycol, 0.01% Benzo[a]isothiazolinone Potassium, 0.5% Silicone Oil, Deionized Water to make up the balance;

[0045] Preparation method: According to the formula ratio, the active ingredients, surfactants and other functional additives are placed in the reaction vessel in sequence, water is added and mixed evenly, and then subjected to high-speed shearing, wet sand milling and finally homogenization filtration to obtain the suspension product.

[0046] Preparation Example 3: 16% Cyclobutrifluram·Jinggangmycin Suspension (1:3)

[0047] Formula composition: 4% Cyclobutrifluram, 12% Jinggangmycin, 2% Alkylphenol polyoxyethylene ether phosphate, 1% Lignosulfonate, 3% Alkyl aryl polyoxyethylene ether polyoxypropylene ether, 0.25% Xanthan gum, 5% Ethylene glycol, 0.1% Sodium benzoate, 0.5% Silicone oil, deionized water to make up the balance;

[0048] Preparation method: Same as in preparation example 2.

[0049] Preparation Example 4: 24% Cyclobutrifluram·Jinggangmycin wettable powder (3:1)

[0050] Formula composition: 18% Cyclobutrifluram, 6% Jinggangmycin, 8% Naphthalenesulfonate formaldehyde condensate, 4% BX (a type of chemical compound), 1% sodium polycarboxylate, 1% sodium dodecyl sulfate, and kaolin to make up the balance;

[0051] Preparation method: According to the formula ratio, the active ingredients, dispersants, wetting agents and fillers are mixed and stirred evenly in a mixing tank. The mixture is then pulverized and mixed evenly multiple times by an air jet mill to prepare the required wettable powder.

[0052] Preparation Example 5: 12% Cyclobutrifluram·Kasugamycin Wettable Powder (1:5)

[0053] Formula composition: 2% Cyclobutrifluram, 10% Kasugamycin, 2% Naphthalenesulfonate formaldehyde condensate, 7% Sodium lignosulfonate, 3% BX (a type of lignosulfonate), 2% Ammonium sulfate, and kaolin supplement.

[0054] Preparation method: Same as in preparation example 4.

[0055] Preparation Example 6: 15% Cyclobutrifluram·Kasugamycin Suspension (2:3)

[0056] Formula composition: 6% Cyclobutrifluram, 9% Kasugamycin, 1% Fatty alcohol polyoxyethylene ether, 1% Block polyether, 1% Isomerized alcohol polyoxyethylene ether, 1% Naphthalene sulfonate formaldehyde condensate, 3% Styrene-phenol polyoxyethylene ether phosphate, 2% Magnesium aluminum silicate, 0.2% Carboxyethyl cellulose, 1% Sodium benzoate, 5% Ethylene glycol, 0.5% Silicone oil, deionized water to make up the balance;

[0057] Preparation method: Same as in preparation example 2.

[0058] Preparation Example 7: 21% Cyclobutrifluram·Kasugamycin Water Dispersible Granules (5:2)

[0059] Formula composition: 15% Cyclobutrifluram, 6% Kasugamycin, 4% Naphthalenesulfonate formaldehyde condensate, 6% Lignosulfonate, 2% Sodium dodecyl sulfate, 5% Silica, 30% Starch, and Kaolin as a supplement.

[0060] Preparation method: According to the formula ratio, add the active ingredients to the carrier, and add surfactants and other functional additives to it. Mix, and after air jet pulverization, add 10-25% water. Then knead, granulate, dry and sieve to obtain water-dispersible granules; or spray water, granulate and dry the pulverized powder in a fluidized bed granulator, and then sieve to obtain the product.

[0061] Preparation Example 8: 14% Cyclobutrifluram·Shenqinmycin Suspension (5:2)

[0062] Formula composition: 10% Cyclobutrifluram, 4% Shenqinmycin, 1% Isotrigine tridecyl alcohol polyoxyethylene ether, 1% Naphthalene sulfonate formaldehyde condensate, 2% Styrene phenol polyoxyethylene ether phosphate, 2% Alkyl aryl polyoxyethylene ether polyoxypropylene ether, 0.25% Xanthan gum, 1% Magnesium aluminum silicate, 5% Propylene glycol, 0.2% Potassium benzoate, 0.5% Organosilicone defoamer, deionized water to make up the balance;

[0063] Preparation method: Same as in preparation example 2.

[0064] Preparation Example 9: 18% Cyclobutrifluram·Shenqinmycin Suspension (1:5)

[0065] Formula composition: 3% Cyclobutrifluram, 15% Shenqinmycin, 3% Alkylphenol Polyoxyethylene Ether, 4% Alkylphenol Polyoxyethylene Ether Phosphate, 1% Sodium Polycarboxylate, 0.25% Xanthan Gum, 5% Ethylene Glycol, 0.15% Sodium Benzoate, 0.5% Silicone Defoamer, deionized water to make up the balance;

[0066] Preparation method: Same as in preparation example 2.

[0067] Example 1: Indoor bioactivity assay of different agents on pathogens

[0068] Experimental basis: The experiment was conducted in accordance with NY / T 1156.2-2006, the Agricultural Industry Standard of the People's Republic of China, "Guidelines for Indoor Bioassay Tests of Pesticides - Fungicides Part 2: Tests for Inhibition of Mycelial Growth of Pathogenic Fungi - Plate Method".

[0069] Experimental target: Fusarium graminearum, the pathogen of wheat scab.

[0070] Test reagents: tetracycline technical, jinggangmycin technical, shenqinmycin technical, kasugamycin technical, and cyclobutrifluram technical.

[0071] Drug preparation: Dissolve the original drug in a suitable solvent, then dilute with 0.1% Tween 80 aqueous solution to prepare single-dose stock solutions. Design different ratios according to the purpose of mixing and drug activity. Prepare the required series of mass concentrations for each single drug and each group of mixed solutions.

[0072] Experimental replication: Each concentration of the test reagent was replicated 4 times, with a 0.1% Tween 80 aqueous solution without the reagent as a blank control.

[0073] Drug treatment: Under aseptic conditions, according to the test treatment, pre-melted and sterilized PDA culture medium was quantitatively added to a sterile conical flask. 10 mL of each prepared treatment solution was quantitatively taken from low concentration to high concentration and added to the conical flasks respectively. The solutions were shaken thoroughly and then poured into petri dishes in equal amounts to prepare drug-containing plates of the corresponding concentrations.

[0074] Inoculation: Under aseptic conditions, use a sterilized punch to cut a mycelial cake from the edge of a pre-cultured Fusarium graminearum colony. Use an inoculator to inoculate the mycelial cake into the center of a drug-containing plate, cover it with the cap, and place it in a constant temperature and light incubator at 26°C for dark incubation.

[0075] Data collection: The growth of pathogenic fungal hyphae was investigated based on the growth of hyphae in the blank control culture dishes. The diameter of the colonies was measured in centimeters (cm) using a ruler. The diameter of each colony was measured once using the cross-sectional method, and the average value was taken. The original data of all replicates for each treatment were recorded.

[0076] Data statistics and analysis: Based on the survey results, the inhibition rate of mycelial growth of the tested target bacteria by each treatment concentration was calculated, in percentage (%). The calculation results were retained to two decimal places.

[0077] D = D1 - D2

[0078] In the formula:

[0079] D – Colony growth diameter;

[0080] D1—colony diameter;

[0081] D2 – Diameter of the mushroom cake.

[0082]

[0083] In the formula:

[0084] I – Mycelial growth inhibition rate;

[0085] D0—Correlation diameter of the blank control group;

[0086] D T — Diameter of colonies grown after chemical treatment.

[0087] The DPS statistical analysis system was used to analyze and derive the virulence regression equation and EC. 50 The value is used to evaluate the activity of the test reagent on the biological sample.

[0088] Sun Yunpei's method: The synergistic effect of drug mixtures is evaluated based on the co-toxicity coefficient (CTC). A CTC ≥ 120 indicates a synergistic effect; a CTC ≤ 80 indicates an antagonistic effect; and a CTC < 120 indicates an additive effect.

[0089] Calculation of the co-toxicity coefficient (CTC value) of the mixture:

[0090]

[0091] In the formula:

[0092] ATI – Actual Measured Toxicity Index of Mixtures;

[0093] S—EC of standard reagent 50 The unit is milligrams per liter (mg / L);

[0094] M – EC of the mixture 50 The unit is milligrams per liter (mg / L).

[0095] TTI = TI A ×P A +TI B ×P B

[0096] In the formula:

[0097] TTI – Theoretical Toxicity Index of Mixtures;

[0098] TI A —A. Toxicity index of drug A;

[0099] P A —Percentage content of drug A in the mixture, expressed as percentage (%);

[0100] TI B —Toxicity index of drug B;

[0101] P B —Percentage content of agent B in the mixture, expressed as percentage (%).

[0102]

[0103] In the formula:

[0104] CTC – Cotoxicity Coefficient;

[0105] ATI – Actual Measured Toxicity Index of Mixtures;

[0106] TTI – Theoretical Toxicity Index of Mixtures.

[0107] The test results are shown in the table below:

[0108] Table 1. Results of in vitro toxicity assays of Cyclobutrifluram combined with tetramycin against Fusarium graminearum, the causal agent of wheat blight.

[0109]

[0110] Table 2. Results of indoor toxicity assays of Cyclobutrifluram combined with Jinggangmycin against Fusarium graminearum, the causal agent of wheat blight.

[0111]

[0112] Table 3. Results of indoor toxicity assays of Cyclobutrifluram combined with shenqinmycin against Fusarium graminearum, the causal agent of wheat blight.

[0113]

[0114]

[0115] Table 4. Results of indoor toxicity assays of Cyclobutrifluram combined with Kasugamycin against Fusarium graminearum, the causal agent of wheat blight.

[0116]

[0117] The results of the indoor tests (see Tables 1-4) show that Cyclobutrifluram, when combined with any one of tetramycin, jinggangmycin, shenqinmycin, or kasugamycin, exhibits a good inhibitory effect on wheat scab at a certain mass ratio. Cyclobutrifluram exhibits a synergistic effect against wheat scab when the mass ratio of Cyclobutrifluram to tetramycin is 1:32–48:1, with a co-toxicity coefficient greater than 120. However, at mass ratios of 1:48 and 50:1, the effect is additive. Similarly, Cyclobutrifluram exhibits a synergistic effect against wheat scab when the mass ratio of Cyclobutrifluram to Jinggangmycin is 1:24–52:1, but at a mass ratio of 1:48, the effect is additive. Likewise, Cyclobutrifluram exhibits a synergistic effect against wheat scab when the mass ratio of Cyclobutrifluram to Shenqinmycin is 1:30–20:1, but at a mass ratio of 30:1, the effect is additive. Finally, Cyclobutrifluram exhibits a synergistic effect against wheat scab when the mass ratio of Cyclobutrifluram to Kasugamycin is 1:40–20:1, but at a mass ratio of 30:1–40:1, the effect is additive.

[0118] Example 2: Field efficacy trial of pesticides for controlling wheat scab

[0119] Experimental basis: This experiment was conducted in accordance with NY / T 1464.15-2007 "Field Efficacy Test Guidelines for Pesticides Part 15: Control of Wheat Fusarium Head Blight by Fungicides".

[0120] Test subject: Wheat scab.

[0121] Experimental crop: Wheat (Zhengmai 9023).

[0122] Experimental environmental conditions: The experiment was conducted in Qinnan Town, Yandu District, Yancheng City, Jiangsu Province. The soil in the experimental site was clay with medium to high fertility. Wheat scab disease has been a serious problem in recent years. The cultivation conditions in all experimental plots were uniform and consistent with local good agricultural practices.

[0123] Plot arrangement: The experimental reagent, control reagent, and blank control were arranged in a randomized block design, with each plot having a test area of ​​20m². 2 Each treatment was repeated 4 times.

[0124] Application method and number of applications: The first application was carried out on May 2, 2022, and the second application was carried out 7 days later (May 9). The Gongnong-16 sprayer was used for conventional spraying.

[0125] Experimental survey method: The control effect was investigated 12 days before harvest. During the survey, five points were sampled in each plot, and 100 ears were surveyed at each point. The ears were graded according to the percentage of dead ears to the total ear area, and the number of diseased ears and the total number of ears were recorded.

[0126] Grading method:

[0127] Grade 0: Disease-free entire ear of grain;

[0128] Grade 1: The area of ​​dead ears accounts for less than 1 / 4 of the total ear area;

[0129] Grade 3: The area of ​​dead ears accounts for 1 / 4 to 1 / 2 of the total ear area;

[0130] Grade 5: The area of ​​dead ears accounts for 1 / 2 to 3 / 4 of the total ear area;

[0131] Grade 7: The area of ​​withered ears accounts for more than 3 / 4 of the total ear area;

[0132] Methods for calculating drug efficacy:

[0133]

[0134] The results of the field efficacy survey are shown below:

[0135] Table 5 Results of field efficacy trials for controlling wheat scab.

[0136] serial number Drug Name Dosage of active ingredient (g / hectare) Disease index Prevention and control efficacy (%) 1 14% Cyclobutrifluram·Tetramycin Suspension (6:1) 3 1.54 92.10 2 15% Cyclobutrifluram·Kasugamycin Suspension (2:3) 35 2.08 89.36 3 24% Cyclobutrifluram·Jinggangmycin Wettable Powder (3:1) 40 2.49 87.23 4 14% Cyclobutrifluram·Shenqinmycin Suspension (5:2) 100 2.59 86.72 5 0.3% Tetracycline Aqueous Solution 3 7.56 61.30 6 35% Cyclobutrifluram wettable powder 100 5.67 70.96 7 6% Kasugamycin Wettable Powder 36 6.02 69.17 8 1% Shenqinmycin suspension 120 6.46 66.93 9 24% Jinggangmycin Aqueous Solution 40 6.89 64.70 10 Water comparison / 19.53 -

[0137] The experimental results in the table above show that the pesticide composition of the present invention has excellent control effect on wheat scab. Compared with the single-agent control, the compound formulations in each preparation example achieved better control of wheat scab. Throughout the experiment, wheat growth was observed periodically, and no adverse effects of any pesticide treatment on wheat growth were found.

[0138] The results of indoor and field efficacy trials show that this invention, by combining Cyclobutrifluram with any one of tetracycline, kasugamycin, jinggangmycin, and shenzimidicin in a reasonable ratio, has a good control effect on wheat scab. Furthermore, it has no adverse effects on wheat growth.

Claims

1. A pesticide composition and its use, characterized in that, The pesticide composition comprises active ingredient A and active ingredient B, wherein active ingredient A is Cyclobutrifluram and active ingredient B is shenqinmycin.

2. The pesticide composition according to claim 1, characterized in that, The mass ratio of active ingredient A to active ingredient B is 1:48 to 1:

52.

3. The pesticide composition according to claim 2, characterized in that, The mass ratio of active ingredient A to active ingredient B is 1:30 to 20:

1.

4. The pesticide composition according to claim 3, characterized in that, The mass ratio of active ingredient A to active ingredient B is 1:20 to 10:

1.

5. The pesticide composition according to claim 1, characterized in that, Based on the total weight of the pesticide composition, which is 100%, the total weight of active ingredient A and active ingredient B accounts for 0.1% to 80% of the total weight of the fungicide composition.

6. The pesticide composition according to claim 1, characterized in that, In addition to the active ingredient, the pesticide composition also contains pesticide-permitted auxiliary ingredients, which are selected from one or more of the following: wetting agents, dispersants, emulsifiers, thickeners, disintegrants, antifreeze agents, defoamers, solvents, preservatives, stabilizers, synergists, binders, fillers, or carriers.

7. The pesticide composition according to claim 1, characterized in that, The pesticide composition can be prepared into a pesticide-acceptable formulation, which can be a solid or liquid formulation.

8. The pesticide composition according to claim 7, characterized in that, The solid dosage forms are granules, strips, wettable powders, oil-dispersible powders, emulsion powders, water-dispersible granules, emulsion granules, water-dispersible tablets, soluble powders, soluble tablets, or soluble granules. The liquid dosage forms are soluble solutions, soluble gels, oils, film-spreading oils, emulsions, latexes, dispersible liquids, ointments, water emulsions, oil emulsions, microemulsions, lipids, suspensions, microcapsule suspensions, oil suspensions, dispersible oil suspensions, or suspension emulsions.

9. Use of the pesticide composition according to any one of claims 1-8 for the prevention and control of plant diseases.

10. The use according to claim 9, characterized in that, The plant disease mentioned is wheat scab.

Images