Traditional Chinese medicine ointment containing deer sinew powder and tortoise shell powder and preparation method of traditional Chinese medicine ointment

Abstract

The invention discloses a traditional Chinese medicine ointment containing deer sinew powder and tortoise shell powder and a preparation method thereof. The traditional Chinese medicine ointment is prepared from the following raw materials in parts by weight: 5-10 parts of deer sinew powder, 3-6 parts of deer tortoise shell powder, 8-12 parts of radix bupleuri, 8-12 parts of radix curcumae, 10-15 parts of spica prunellae, 10-15 parts of bulbus fritillariae thunbergii, 8-12 parts of radix angelicae sinensis, 6-10 parts of rhizoma chuanxiong, 5-8 parts of frankincense, 5-8 parts of myrrh, 100-150 parts of vaseline and 20-30 parts of beewax. According to the invention, the defects of limited effect, single curative effect, shallow action level, poor long-term effect and the like due to the adoption of conventional medicinal materials for soothing liver, regulating qi, promoting blood circulation and removing blood stasis in the use process of the existing external ointment are overcome.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of traditional Chinese medicine preparation, in particular to a traditional Chinese medicine ointment containing deer tendon powder and deer antler velvet powder and a preparation method thereof. BACKGROUND

[0002] Traditional Chinese medicine ointment is an important form of traditional Chinese medicine external preparation, which is a semi-solid or ointment-like substance prepared by adding suitable matrix to the processed traditional Chinese medicine materials through extraction, decoction and concentration processes, and is mainly used for skin surface application. The traditional Chinese medicine ointment containing deer tendon powder and deer antler velvet powder is to add deer products into the ointment.

[0003] A kind of external ointment in Chinese patent application No. 201310670177.8 includes the following components by weight: Chuanxiong 5-12, Honghua 5-15, Lurong 5-15, Baifuzi 5-15, Ru xiang 2-8, Baijiezi 3-10, Fangfeng 2-10, Wujiapi 2-8, Duzhong 1-7, M ayou 2-8, Moshe 1-10, Duhuo 1-8, Bai zhi 1-6, Shenzhengcao 2-8, Caowutou 5-12, Chenxiang 2-8, Muxiang 5-12, Zhebeimu 2-8, Sangbaipi 2-10, Zhan dan 1-8, Sanqi 2-8, Baihuashexiecao 5-10. The external ointment uses Lurong, a deer product, as raw material. Deer antler velvet is the un-ossified young horn of Cervidae, which also belongs to Lurong. Lurong contains various active ingredients such as amino acids, growth factors, polypeptides, and phospholipids, and has the effects of promoting cell proliferation, accelerating wound healing, and improving tissue nutrition. In the external ointment, Lurong is used to assist the treatment of skin ulcers, chronic sores, and soft tissue injuries.

[0004] As an important part of external treatment of traditional Chinese medicine, the external ointment is widely used in the treatment of injuries, muscle and bone pain, and rheumatic arthralgia. Most of the currently used and commercially available external ointments are based on the traditional treatment methods of soothing liver and regulating qi, promoting blood circulation to remove blood stasis, and dredging collaterals to relieve pain, and often use conventional medicinal materials such as Ru xiang, M oyu, Honghua, Chuanxiong, and Danggui. Although these ointments have certain effects in relieving acute pain and eliminating local swelling, they often treat the symptoms rather than the root cause and have limited long-term effects in treating chronic overuse injuries, weakness of muscles and bones, and difficulty in joint flexion and extension caused by liver and kidney deficiency, and thus are difficult to fundamentally improve the function of muscles and bones.

[0005] Deer tendon is the dried tendon of Cervidae, which is warm in nature and salty in taste, and belongs to the liver and kidney channels. It has the effects of tonifying liver and kidney, strengthening muscles and bones, and dispelling wind and dampness, and is often used to treat soreness and weakness of the waist and knees, weakness of muscles and bones, and rheumatic arthralgia, and is a key drug for treating deficiency-type muscle and bone diseases. Deer antler velvet has the effects of clearing heat and resolving toxicity, softening and resolving nodules, and has a unique effect of resolving phlegm and resolving nodules. However, there is no mature scheme for the systematic application of deer tendon, deer antler velvet, and other medicinal materials in external ointments, especially in combination with soothing liver and regulating qi, promoting blood circulation to remove blood stasis, and other drugs to achieve synergistic effects.

[0006] Therefore, it is urgent to develop a new type of traditional Chinese medicine ointment which can not only exert the instant analgesic effect of traditional blood-activating and collateral-unblocking drugs, but also can supplement liver and kidney and strengthen bones by deer tendon, and eliminate pathological accumulation by deer antler velvet to achieve the treatment of both symptoms and root causes, so as to overcome the defects of single effect, shallow effect level and poor long-term effect in the prior art and improve the comprehensive treatment level of diseases. SUMMARY

[0007] The purpose of the present application is to provide a traditional Chinese medicine ointment containing deer tendon powder and deer antler velvet powder and a preparation method thereof, which solves the problem that the existing ointment uses conventional liver-soothing and qi-regulating and blood-activating and stasis-removing medicinal materials, and has limited effect, single effect, shallow effect level and poor long-term effect in the prior art.

[0008] To achieve the above purpose, the present application provides the following technical scheme: a traditional Chinese medicine ointment containing deer tendon powder and deer antler velvet powder, comprising the following raw materials by weight:

[0009] Deer tendon powder 5-10 parts, deer antler velvet powder 3-6 parts, Radix Bupleuri 8-12 parts, Radix Curcumae 8-12 parts, Prunella vulgaris 10-15 parts, Fritillaria thunbergii Miq. 10-15 parts, Angelica sinensis 8-12 parts, Ligusticum chuanxiong 6-10 parts, Olibanum 5-8 parts, Myrrh 5-8 parts, petrolatum 100-150 parts, beeswax 20-30 parts.

[0010] A preparation method of a traditional Chinese medicine ointment containing deer tendon powder and deer antler velvet powder, comprising the following steps:

[0011] S1, extraction and concentration, six traditional Chinese medicinal materials of Radix Bupleuri, Radix Curcumae, Prunella vulgaris, Fritillaria thunbergii Miq., Angelica sinensis and Ligusticum chuanxiong are decocted twice with water, each time for 1-2 hours, the filtrates of the two times of decoction are combined, and the filtrate is heated and concentrated to form a thick paste;

[0012] S2, mixing and powdering, deer tendon powder, deer antler velvet powder, Olibanum and Myrrh are added to the obtained thick paste, and stirred uniformly, then the mixture is dried, crushed and sieved to form uniform fine powder;

[0013] S3, shaping and ointment making, petrolatum and beeswax are placed in a container and heated to completely melt, then the prepared fine powder is added to the melted base, and stirred and mixed uniformly, finally the mixture is left to stand and naturally cool and solidify to obtain the finished traditional Chinese medicine ointment.

[0014] Preferably, in the preparation method of the traditional Chinese medicine ointment containing deer sinew powder and deer antler powder, before stirring in S2, the thick ointment raw materials are transferred using a diaphragm pump and sealed pipeline, and the thick ointment raw materials are delivered into the tank of the planetary mixer in the mixing process. The weighing sensor at the bottom of the tank monitors and confirms the transferred amount of the thick ointment in real time, and the signal is fed back to the central control system. When the set weight is reached, the central control system closes the diaphragm pump to stop feeding. The four powders of deer sinew powder, deer antler powder, frankincense and myrrh are respectively stored in independent powder storage bins. Each bin is connected with a loss-in-weight feeder or a screw meter below, so as to accurately control the discharging speed and weight of the powder. The powder is automatically fed into the tank of the planetary mixer in sequence through the sealed pipeline and the gas conveyor. During the powder feeding process, the weighing sensor and the central control system confirm the actual feeding amount and the target value, and control the feeding error within ±0.5%.

[0015] Preferably, in the preparation method of the traditional Chinese medicine ointment containing deer sinew powder and deer antler powder, when stirring, the planetary mixer is started through the central control system. The driving device of the planetary mixer drives the stirring paddle and the dispersion disc to rotate. In the rotating process, the stirring paddle stirs and mixes the ointment raw materials and the powder raw materials, and the dispersion disc scatters the raw materials to avoid accumulation. In the stirring process, the central control system adjusts the rotating speed of the driving device. When the rotating speed is controlled at 30-40 rpm at 10-15 min, and the rotating speed is controlled at 40-50 rpm at 15-30 min. The planetary mixer is provided with a temperature sensor and a water jacket. The temperature sensor detects the stirring temperature of the raw materials, and the detection data is transmitted to the central control system. When the detected temperature is higher than the set temperature range, the cooling water in the water jacket is circulated to cool the raw materials and prevent the loss of active ingredients due to high temperature. When the temperature is lower than the set temperature range, the warm water in the water jacket is circulated to heat the raw materials to prevent the thick ointment from being too cold and solidified.

[0016] As the preparation method of the traditional Chinese medicine ointment containing deer sinew powder and deer antler powder of the present application is preferred, in S2, the mixture is dried by a screw pump to transport the mixed mixture from the planetary mixer to the cloth device of the vacuum belt dryer, the cloth device continuously and uniformly coats the mixed mixture in the form of mud on the first layer of stainless steel conveyor belt through a scraper, the conveyor belt slowly moves in the closed vacuum drying chamber, the material runs down layer by layer with the conveyor belt, multi-layer drying is realized, an electric heating assembly is arranged in the vacuum drying chamber to heat the air temperature in the vacuum drying chamber to 60-80℃, the vacuum drying chamber is connected with a vacuum system, vacuum suction is performed on the inside of the vacuum drying chamber, the vacuum degree is-0.08MPa to-0.095MPa, the end of the conveyor belt is provided with a near-infrared moisture detector to monitor the moisture content of the dried material in real time, when the moisture content is qualified, it is transported to the discharge device, and when the moisture content is higher than the set content, the material is dried again.

[0017] As the preparation method of the traditional Chinese medicine ointment containing deer sinew powder and deer antler powder of the present application is preferred, the dried material becomes dry, crisp, flaky or thin layer, and runs to the end of the conveyor belt, the discharge device is provided with a rotary scraper to scrape the material on the conveyor belt, the scraped material enters the material hopper of the discharge device, the material hopper is provided with a pre-crushing mechanism, the pre-crushing mechanism crushes the flaky material by the relative rotation of the crushing rollers, and the granular material is obtained, the granular material is discharged through the discharge valve at the bottom of the material hopper and enters the collection container.

[0018] As the preparation method of the traditional Chinese medicine ointment containing deer sinew powder and deer antler powder of the present application is preferred, in S2, the granular material is placed in the vibrating feeder, the vibrating feeder uniformly and continuously transports the granular material to the fluidized bed jet mill, the fluidized bed jet mill generates high-speed airflow through the supersonic nozzle, the granular material is crushed by mutual collision and friction in the crushing cavity under the action of the airflow, the fine powder generated by crushing rises with the airflow, and the coarse particles return to the crushing area under the action of centrifugal force to continue crushing, realizing high-efficiency and low-temperature crushing and avoiding degradation of heat-sensitive components.

[0019] As a kind of Chinese medicine ointment containing deer sinew powder and deer antler powder of the application, preferably, the superfine powder from airflow pulverizer enters high-speed mixing modifier machine with airflow, and the powder rotates at high speed in the high-speed mixing modifier machine, and the central control system starts micro-dosing pump, and the hydrophobic modifier prepared in advance is atomized through precision nozzle and then uniformly sprayed into the powder flow rotating at high speed, under high-speed stirring, the powder particles and the atomized modifier fully contact, the modifier molecules are physically adsorbed or chemically bonded on the surface of the particles to form a hydrophobic film, which changes the originally hydrophilic surface of the Chinese medicine powder into hydrophobic surface, significantly reduces the surface energy and agglomeration tendency, so that the powder can be uniformly distributed in the vaseline, and the modified powder enters the cyclone separator, most of the powder is separated and collected, and the fine powder carried by the tail gas is further captured by pulse back-blowing bag-type dust collector, and the collected modified powder is sent to the screening system through airtight pipeline.

[0020] As a kind of Chinese medicine ointment containing deer sinew powder and deer antler powder of the application, preferably, when the mixture is screened in S2, the powder enters the screening system and first falls into the feed buffer bin, the weight sensor at the bottom of the buffer bin detects that the material reaches the set amount, and then the central control system starts the vibrating feeder, which uniformly and continuously feeds the powder into the feed inlet of the circular vibrating screen at a set frequency and amplitude, the powder enters the screening machine and does three-dimensional elliptical motion under the drive of the eccentric vibrating motor, the material is quickly dispersed and jumped on the screen surface, the particles smaller than the screen hole quickly pass through the screen, and the particles larger than the screen hole move to the discharge port, the screen is provided with a bouncing ball which continuously jumps under the screen and hits the screen to prevent the fine powder from blocking the screen hole.

[0021] As a kind of Chinese medicine ointment containing deer sinew powder and deer antler powder of the application, preferably, the qualified fine powder is transported to the powder feed inlet of the ointment mixing tank, the melted vaseline and beeswax are also transported into the ointment mixing tank, the mixing structure inside the ointment mixing tank mixes the fine powder, vaseline and beeswax to obtain finished Chinese medicine ointment, and the screened particles are directly transported back to the airflow pulverizer through the recycling pipeline for regrinding, realizing material recycling.

[0022] Compared with the prior art, the application has the following advantages:

[0023] 1. This invention uses deer tendon powder and deer tortoise shell powder as core components, combined with various traditional Chinese medicinal herbs that promote blood circulation, remove blood stasis, soothe the liver, regulate qi, resolve phlegm, and dissipate nodules, to synergistically exert therapeutic effects. Deer tendon powder has the effects of strengthening tendons and bones, nourishing blood, and unblocking meridians, while deer tortoise shell powder has the effects of promoting blood circulation, eliminating masses, dissipating nodules, and relieving pain. The combination of the two can enhance the effects of unblocking meridians, dissipating nodules, promoting blood circulation, and relieving pain. Combined with Bupleurum and Curcuma to soothe the liver and relieve depression, Prunella vulgaris and Fritillaria thunbergii to clear heat, resolve phlegm, soften hardness, and dissipate nodules, Angelica sinensis and Ligusticum chuanxiong to promote blood circulation and nourish blood, and Boswellia carterii and Commiphora myrrha to promote qi, promote blood circulation, reduce swelling, and relieve pain, the combined effects of these herbs have significant conditioning and improvement effects on diseases such as breast hyperplasia, thyroid nodules, and benign lumps caused by qi stagnation, blood stasis, and phlegm accumulation.

[0024] 2. This invention uses petrolatum and beeswax as a matrix, allowing the drug to be released slowly and act on the affected area for a longer period, increasing the local drug concentration and enhancing the therapeutic effect. It also has good skin adhesion and stability. The external application method avoids the first-pass effect of the liver, reduces gastrointestinal irritation, and improves the safety of medication. The overall formula follows the principles of syndrome differentiation and treatment in traditional Chinese medicine, with a reasonable combination of the functions of promoting blood circulation, clearing the meridians, resolving phlegm and dissipating nodules, and regulating qi and relieving pain. It is suitable for a variety of chronic diseases caused by qi and blood imbalance and meridian blockage, and has the advantages of definite curative effect, convenient use, and few side effects. Attached Figure Description

[0025] Figure 1 This is a flowchart of the preparation method of the present invention. Detailed Implementation

[0026] Example 1

[0027] A traditional Chinese medicine ointment containing deer tendon powder and deer tortoise shell powder comprises the following raw materials in parts by weight:

[0028] 7.5 parts deer tendon powder, 4.5 parts deer tortoise shell powder, 10 parts bupleurum, 10 parts turmeric, 12.5 parts prunella vulgaris, 12.5 parts fritillaria thunbergii, 10 parts angelica sinensis, 8 parts chuanxiong rhizome, 6.5 parts frankincense, 6.5 parts myrrh, 125 parts petrolatum, and 25 parts beeswax.

[0029] By using deer tendon powder and deer tortoise shell powder as core components, combined with various traditional Chinese medicinal herbs that promote blood circulation, remove blood stasis, soothe the liver, regulate qi, resolve phlegm, and dissipate nodules, the therapeutic effects are synergistic. Deer tendon powder has the effects of strengthening tendons and bones, nourishing blood and unblocking meridians, while deer tortoise shell powder has the effects of promoting blood circulation, eliminating masses, dissipating nodules, and relieving pain. The combination of the two can enhance the effects of unblocking meridians, dissipating nodules, promoting blood circulation, and relieving pain. Combined with Bupleurum and Curcuma to soothe the liver and relieve depression, Prunella vulgaris and Fritillaria thunbergii to clear heat, resolve phlegm, soften hardness, and dissipate nodules, Angelica sinensis and Ligusticum chuanxiong to promote blood circulation and nourish blood, and Boswellia carterii and Commiphora myrrha to promote qi and blood circulation, reduce swelling, and relieve pain, the combined effects of these herbs have a significant conditioning and improvement effect on diseases such as breast hyperplasia, thyroid nodules, and benign lumps caused by qi stagnation, blood stasis, and phlegm accumulation.

[0030] The vaseline and the beeswax are adopted as the matrix, the drug efficacy can be released slowly and has a long-term effect on the affected part, the local drug concentration is improved, the treatment effect is enhanced, meanwhile, the vaseline and the beeswax have good skin sticking and stability, the external administration mode avoids the liver first-pass effect, reduces the gastrointestinal stimulation, improves the drug safety, the whole formula follows the principle of syndrome differentiation and treatment in traditional Chinese medicine, the formula is reasonable, has the functions of activating blood and dredging collaterals, resolving phlegm and resolving masses, and moving qi and relieving pain, is suitable for various chronic diseases caused by qi-blood disorder and meridian obstruction, and has the advantages of exact curative effect, convenient use and small side effect.

[0031] Example 2

[0032] A traditional Chinese medicine ointment containing deer sinew powder and deer antler velvet powder, comprising the following raw materials in parts by weight:

[0033] Deer sinew powder 5 parts, deer antler velvet powder 3 parts, bupleurum 8 parts, curcuma 8 parts, prunella 10 parts, fritillaria 10 parts, angelica 8 parts, chuanxiong 6 parts, frankincense 5 parts, myrrh 5 parts, vaseline 100 parts, beeswax 20 parts.

[0034] The deer sinew powder and the deer antler velvet powder are adopted as the core components, combined with various traditional Chinese medicinal materials for activating blood and resolving stasis, soothing liver and regulating qi, and resolving phlegm and resolving masses, the treatment effect is synergistically achieved, the deer sinew powder has the effects of strengthening muscles and bones, and nourishing blood and dredging collaterals, the deer antler velvet powder has the effects of activating blood, resolving masses, and relieving pain, the combination of the two can enhance the effects of dredging collaterals and resolving masses, activating blood and relieving pain, in combination with bupleurum and curcuma for soothing liver and relieving depression, prunella and fritillaria for clearing heat and resolving phlegm, softening and resolving masses, angelica and chuanxiong for activating blood and nourishing blood, frankincense and myrrh for moving qi and activating blood, and resolving masses and relieving pain, the combination of the various medicines has a significant conditioning and improving effect on breast hyperplasia, thyroid nodules, and benign masses caused by qi stagnation and blood stasis, and phlegm accumulation.

[0035] The vaseline and the beeswax are adopted as the matrix, the drug efficacy can be released slowly and has a long-term effect on the affected part, the local drug concentration is improved, the treatment effect is enhanced, meanwhile, the vaseline and the beeswax have good skin sticking and stability, the external administration mode avoids the liver first-pass effect, reduces the gastrointestinal stimulation, improves the drug safety, the whole formula follows the principle of syndrome differentiation and treatment in traditional Chinese medicine, the formula is reasonable, has the functions of activating blood and dredging collaterals, resolving phlegm and resolving masses, and moving qi and relieving pain, is suitable for various chronic diseases caused by qi-blood disorder and meridian obstruction, and has the advantages of exact curative effect, convenient use and small side effect.

[0036] Example 3

[0037] A traditional Chinese medicine ointment containing deer sinew powder and deer antler velvet powder, comprising the following raw materials in parts by weight:

[0038] Deer sinew powder 10 parts, deer antler velvet powder 6 parts, bupleurum 12 parts, curcuma 12 parts, prunella 15 parts, fritillaria 15 parts, angelica 12 parts, chuanxiong 10 parts, frankincense 8 parts, myrrh 8 parts, vaseline 150 parts, beeswax 20-30 parts.

[0039] By taking deer sinew powder and deer antler velvet powder as core components, combined with various traditional Chinese medicinal materials for promoting blood circulation to remove blood stasis, soothing liver and regulating qi, and resolving phlegm and resolving mass, the treatment effect is synergistically played. Deer sinew powder has the effects of strengthening muscles and bones, nourishing blood and dredging collaterals. Deer antler velvet powder has the effects of promoting blood circulation to remove stasis and resolving mass to relieve pain. The combination of the two can enhance the effects of dredging collaterals, resolving mass, promoting blood circulation and relieving pain. In combination with Chaihu, Yujin for soothing liver and relieving depression, Xia Shucao and Zhebeimu for clearing heat and resolving phlegm and softening and resolving mass, Danggui and Chuanxiong for promoting blood circulation and nourishing blood, and Ru Xiang and Mo Yao for promoting blood circulation and relieving pain, the combination of the various drugs has a significant conditioning and improving effect on breast hyperplasia, thyroid nodules, and benign masses caused by qi stagnation and blood stasis and phlegm accumulation.

[0040] By using vaseline and beeswax as the matrix, the drug efficacy can be released slowly and has a long-lasting effect on the affected area, improving the local drug concentration and enhancing the treatment effect. At the same time, it has good skin adhesion and stability. The external administration avoids the first-pass effect of the liver and reduces the stimulation of the gastrointestinal tract, improving the safety of drug use. The overall formula follows the principle of diagnosis and treatment in traditional Chinese medicine, and the prescription is reasonable, with the functions of promoting blood circulation and dredging collaterals, resolving phlegm and resolving mass, and promoting qi circulation and relieving pain. It is suitable for various chronic diseases caused by blood and qi imbalance and meridian obstruction, and has the advantages of definite curative effect, convenient use, and small side effects.

[0041] Example 4

[0042] Please refer to Figure 1 A preparation method of a traditional Chinese medicine ointment containing deer sinew powder and deer antler velvet powder, comprising the following steps:

[0043] S1, extraction and concentration, Chaihu, Yujin, Xia Shucao, Zhebeimu, Danggui, and Chuanxiong are decocted with water for 2 times, each time for 1-2 hours. The filtrates of the two times of decoction are combined and concentrated by heating to prepare a thick paste;

[0044] S2, mixing and powdering, deer sinew powder, deer antler velvet powder, Ru Xiang, and Mo Yao are added to the obtained thick paste, and stirred uniformly. The mixture is dried, then pulverized and sieved to prepare a uniform fine powder;

[0045] S3, shaping and ointment making, vaseline and beeswax are placed in a container and heated to completely melt. Then, the prepared fine powder is added to the melted matrix, and stirred and mixed uniformly. Finally, the mixture is left to stand and naturally cool and solidify to obtain the finished traditional Chinese medicine ointment.

[0046] The preparation method realizes efficient integration and uniform dispersion of various effective components through scientific process design. First, water decoction method is used to extract Chaihu, Yujin, Xiaakucao, Zhebeimu, Danggui and Chuanqiong to fully dissolve the water-soluble active ingredients therein and concentrate into thick paste, ensuring the efficacy basis of liver-soothing and qi-regulating, blood-activating and stasis-removing medicinal materials. Then, the precious and fine medicinal materials such as Lujin powder, Lumaopowder, and frankincense and myrrh are mixed with the thick paste, and the mixture is subjected to drying, crushing and sieving to form composite drug powder with uniform particle size. This process avoids the loss of effective components of precious and fine medicinal materials due to long-term high-temperature decoction, and significantly increases the specific surface area of the drug powder through physical crushing, which is beneficial to the uniform distribution in the matrix.

[0047] The method also optimizes the forming process of the external use ointment, improves the product stability and use performance, and directly adds the composite drug powder into the molten vaseline and beeswax mixed matrix, fully stirs to achieve good infiltration and dispersion of the drug powder and the oily matrix, and forms a semi-solid preparation with stable structure after cooling. The process is simple to operate, does not require organic solvents, and is safe. The obtained ointment has delicate texture, moderate adhesion, is easy to apply and not prone to flow, the overall process flow is reasonable, and the traditional Chinese medicine theory and modern preparation technology are taken into account, ensuring the stability, uniformity and bioavailability of the drug, and being beneficial to the comprehensive therapeutic effect of tonifying liver and kidney, strengthening tendons and bones, soothing liver and resolving stagnation, and activating blood and relieving pain.

[0048] Further, before stirring in S2, a diaphragm pump and a sealed pipeline are used to transfer the thick paste raw material to the tank of the planetary mixer in the mixing process. The weighing sensor at the bottom of the tank monitors and confirms the transfer amount of the thick paste in real time, and the signal is fed back to the central control system. When the set weight is reached, the central control system closes the diaphragm pump to stop feeding. The Lujin powder, Lumaopowder, frankincense and myrrh powders are respectively stored in independent powder storage bins. Each bin is connected with a loss-in-weight feeder or a screw meter below, which accurately controls the feeding speed and weight of the powder. The powder is automatically fed into the tank of the planetary mixer in sequence through the closed pipeline and the gas conveyor. During the powder feeding process, the weighing sensor and the central control system confirm the actual feeding amount and the target value, and control the feeding error within ±0.5%.

[0049] Further, when stirring, the planetary mixer is started by the central control system, the driving device of the planetary mixer drives the stirring paddle and the dispersion disc to rotate, in the process of rotation, the stirring paddle stirs and mixes the paste-like raw materials and the powder-like raw materials, the dispersion disc scatters the raw materials to avoid accumulation, in the process of stirring, the central control system adjusts the rotating speed of the driving device, at 10-15 min, the rotating speed is controlled at 30-40 rpm, at 15-30 min, the rotating speed is controlled at 40-50 rpm, the planetary mixer is provided with a temperature sensor and a water jacket, the temperature sensor detects the stirring temperature of the raw materials, and the detection data is transmitted to the central control system, when the detected temperature is higher than the set temperature range, the cooling water in the water jacket is circulated to cool the raw materials to prevent the loss of active ingredients due to excessive temperature, and when the temperature is lower than the set temperature range, the warm water in the water jacket is circulated to heat the raw materials to prevent the paste-like raw materials from being over-cooled and solidified.

[0050] Further, when the mixture is dried in S2, the completed mixture is transported from the planetary mixer to the distributing device of the vacuum belt dryer by the screw pump, the distributing device uniformly coats the mixture in the form of mud on the first layer of stainless steel conveyor belt by the scraper, the conveyor belt slowly moves in the closed vacuum drying chamber, the material runs down layer by layer with the conveyor belt to realize multi-layer drying, the vacuum drying chamber is provided with an electric heating assembly to heat the air temperature in the vacuum drying chamber to 60-80℃, the vacuum drying chamber is connected to a vacuum system to vacuumize the inside of the vacuum drying chamber, the vacuum degree is-0.08MPa to-0.095MPa, the end of the conveyor belt is provided with a near-infrared moisture detector to monitor the moisture content of the dried material in real time, when the moisture content is qualified, it is transported to the discharge device, and when the moisture content is higher than the set content, the material is dried again.

[0051] Further, the dried material becomes dry and crisp in the form of sheet or thin layer, runs to the end of the conveyor belt, the discharge device is provided with a rotary scraper to scrape the material on the conveyor belt, the scraped material enters the material hopper of the discharge device, the material hopper is provided with a pre-crushing mechanism, the pre-crushing mechanism crushes the sheet-like material by the relatively rotating crushing rollers to obtain granular medicinal materials, the granular medicinal materials are discharged through the discharge valve at the bottom of the material hopper and enter the collection container.

[0052] Further, in S2, the mixture is crushed, the medicine particles are put into the vibrating feeder, the vibrating feeder uniformly and continuously sends the medicine particles into the fluidized bed airflow crusher, the fluidized bed airflow crusher generates high-speed airflow through the supersonic nozzle, the medicine particles are crushed by mutual collision and friction under the driving of the airflow, the fine powder generated by crushing rises with the airflow, the coarse particles return to the crushing area under the action of centrifugal force to continue crushing, realizing high-efficiency and low-temperature crushing and avoiding degradation of heat-sensitive components.

[0053] Further, the superfine medicine powder from the airflow crusher enters the high-speed mixing modifier with the airflow, the medicine powder rotates at high speed inside the high-speed mixing modifier, the central control system starts the micro-metering pump, the hydrophobic modifier prepared in advance is atomized through the precision nozzle and uniformly sprayed into the medicine powder flow rotating at high speed, under the high-speed stirring, the medicine powder particles fully contact with the atomized modifier, the modifier molecules physically adsorb or chemically bond on the surface of the particles to form a hydrophobic film, this process changes the originally hydrophilic surface of the traditional Chinese medicine powder into hydrophobic, significantly reduces the surface energy and agglomeration tendency, so that the medicine powder can be uniformly distributed in the vaseline, the modified medicine powder enters the cyclone separator, most of the powder is separated and collected, the fine powder carried by the tail gas is further captured by the pulse back-blowing bag-type dust collector, and the collected modified medicine powder is sent to the screening system through the closed pipeline.

[0054] Further, in S2, the mixture is crushed, the medicine particles are put into the vibrating feeder, the vibrating feeder uniformly and continuously sends the medicine particles into the fluidized bed airflow crusher, the fluidized bed airflow crusher generates high-speed airflow through the supersonic nozzle, the medicine particles are crushed by mutual collision and friction under the driving of the airflow, the fine powder generated by crushing rises with the airflow, the coarse particles return to the crushing area under the action of centrifugal force to continue crushing, realizing high-efficiency and low-temperature crushing and avoiding degradation of heat-sensitive components.

[0055] Further, the qualified fine powder is sent to the medicine powder feeding port of the ointment mixing tank, the melted vaseline and beeswax are also sent to the ointment mixing tank, the mixing structure inside the ointment mixing tank mixes the fine powder, vaseline and beeswax to obtain the finished traditional Chinese medicine ointment, and the screened particles are directly sent back to the airflow crusher for re-crushing, realizing material recycling.

[0056] Through full-process automation and precise process control, the production efficiency, quality uniformity and component stability of the traditional Chinese medicine ointment are significantly improved, each process is connected by closed pipeline and automatic equipment, the thick paste is transferred by a diaphragm pump, a loss-in-weight feeder is used to accurately feed powder, and the central control system is used to monitor the weighing data in real time, so that the feeding error is controlled within ± 0.5%, the high precision of raw material ratio is realized, in the mixing link, a planetary mixer is used in combination with segmented speed regulation and a jacket temperature control system, the stirring intensity and temperature are dynamically adjusted according to the process stage, the paste is prevented from solidifying or the active ingredients from being degraded by heat, the material is ensured to be fully wetted and uniformly mixed, and then vacuum belt drying technology is used to realize continuous and efficient drying under the conditions of 60-80 DEG C low temperature and-0.08 to-0.095 MPa high vacuum, and near-infrared moisture meters are used to detect the end point on line, so that the drying quality is stable, and batch differences caused by manual intervention are avoided.

[0057] The method innovatively integrates the superfine crushing, surface modification and automatic screening integrated process, effectively solves the technical bottleneck that the traditional Chinese medicine powder is difficult to mix with the oily base, the superfine powder obtained through air flow crushing is sprayed with a hydrophobic modifier in a high-speed mixing modifier, a hydrophobic film is formed on the particle surface, the surface energy and the agglomeration tendency are significantly reduced, and the dispersibility and compatibility of the powder in the petrolatum base are greatly improved, the screening system adopts a circular vibrating screen with a bouncing ball net cleaning device, continuous screening and anti-blocking are realized, the coarse particles that do not pass are automatically returned to the crusher for recycling, the final powder is ensured to be uniform in particle size and without waste, the whole process realizes continuous, closed and intelligent operation from extraction to molding, not only improves the product uniformity and stability, but also reduces dust pollution and active ingredient loss, and finally high-quality traditional Chinese medicine ointment with fine texture, stable drug release and reliable curative effect is obtained.

[0058] The hydrophobic modifier is a pharmaceutical grade polyethylene glycol derivative, the pharmaceutical grade polyethylene glycol derivative is PEG-6 white spruce rosin ester or PEG-32 distearate, the hydrophobic modifier improves the interfacial compatibility of the traditional Chinese medicine powder and the oily base, promotes uniform mixing, and is biodegradable and low toxicity, and is commonly used in external ointments and creams.

[0059] The above is only a preferred embodiment of the present application, and is not used to limit the present application, any modification, equivalent replacement and improvement made within the spirit and principle of the present application shall be included in the protection scope of the present application.

Claims

1. A Chinese medicine ointment containing deer sinew powder and deer antler velvet powder, characterized in that, The following raw materials by weight are included: Deer tendon powder 5-10 parts, deer antler velvet powder 3-6 parts, Bupleurum 8-12 parts, Rhizoma Curcumae 8-12 parts, Prunella vulgaris 10-15 parts, Fritillaria 10-15 parts, Angelica 8-12 parts, Chuanxiong 6-10 parts, Olibanum 5-8 parts, Myrrh 5-8 parts, Vaseline 100-150 parts, beeswax 20-30 parts.

2. A preparation method of the Chinese medicine ointment containing deer sinew powder and deer antler velvet powder, which is suitable for the Chinese medicine ointment containing deer sinew powder and deer antler velvet powder according to claim 1, characterized in that, The following steps are included: S1, extraction and concentration, decocting six Chinese herbal medicines of Bupleurum, Rhizoma Curcumae, Prunella vulgaris, Fritillaria, Angelica, Chuanxiong with water for 2 times, each time for 1-2 hours, combining the filtrate of two times of decoction, and heating and concentrating the filtrate to prepare a thick paste; S2, mixing and powdering, adding deer tendon powder, deer antler velvet powder, Olibanum and Myrrh into the thick paste obtained, fully stirring and mixing, drying the mixture, then crushing and sieving to prepare uniform fine powder; S3, forming and pasting, placing Vaseline and beeswax in a container, heating to completely melt, then adding the fine powder prepared into the melted base, fully stirring and mixing, finally, placing the mixture and naturally cooling and solidifying to obtain the finished traditional Chinese medicine ointment.

3. The method for preparing a traditional Chinese medicine ointment containing deer tendon powder and deer tortoise shell powder according to claim 2, characterized in that: Before stirring in S2, using a diaphragm pump and sealed pipeline to transfer the thick paste raw material, transporting the thick paste raw material into the tank of the planetary mixer in the mixing process, the weighing sensor at the bottom of the tank monitors and confirms the transferred amount of the thick paste, the signal is fed back to the central control system, when the set weight is reached, the central control system closes the diaphragm pump to stop feeding, the four powders of deer tendon powder, deer antler velvet powder, Olibanum and Myrrh are respectively stored in independent powder storage bins, each bin is connected with a loss-in-weight feeder or a screw meter below, accurately controlling the discharging speed and weight of the powder, the powder is automatically fed into the tank of the planetary mixer in turn through the sealed pipeline and gas conveyor, during the powder feeding process, the weighing sensor and the central control system confirm the actual feeding amount and the target value, controlling the feeding error within ±0.5%.

4. The method for preparing a traditional Chinese medicine ointment containing deer tendon powder and deer tortoise shell powder according to claim 3, characterized in that: When stirring, the planetary mixer is started by the central control system, the driving device of the planetary mixer drives the stirring paddle and the dispersion disc to rotate, in the process of rotation, the stirring paddle stirs and mixes the paste and powder raw materials, the dispersion disc scatters the raw materials to avoid accumulation, in the process of stirring, the central control system adjusts the speed of the driving device, at 10-15 min, the speed is controlled at 30-40 rpm, at 15-30 min, the speed is controlled at 40-50 rpm, the planetary mixer is installed with a temperature sensor and a water jacket, the temperature sensor detects the stirring temperature of the raw materials, the detection data is transmitted to the central control system, when the detected temperature is higher than the set temperature range, circulating cooling water is circulated in the water jacket to cool the raw materials to prevent the loss of active ingredients due to high temperature, when the temperature is lower than the set temperature range, warm water is circulated in the water jacket to heat the raw materials to prevent overcooling and solidification of the paste.

5. The method for preparing a traditional Chinese medicine ointment containing deer tendon powder and deer tortoise shell powder according to claim 4, characterized in that: In S2, the mixture is dried by screw pump to transport the mixed mixture from the planetary mixer to the distribution device of the vacuum belt dryer. The distribution device coats the mixed mixture on the first layer of stainless steel conveyor belt continuously and uniformly by scraper. The conveyor belt moves slowly in the closed vacuum drying chamber. The material runs down layer by layer with the conveyor belt to realize multi-layer drying. The vacuum drying chamber is provided with an electric heating assembly to heat the air temperature in the vacuum drying chamber to 60-80℃. The vacuum drying chamber is connected to a vacuum system to perform vacuumization on the inside of the vacuum drying chamber. The vacuum degree is -0.08MPa to -0.095MPa. The end of the conveyor belt is provided with a near-infrared moisture detector to monitor the moisture content of the dried material in real time. When the moisture content is qualified, it is transported to the discharge device. When the moisture content is higher than the set content, the material is dried again.

6. The method for preparing a traditional Chinese medicine ointment containing deer tendon powder and deer tortoise shell powder according to claim 5, characterized in that: The dried material becomes dry and crisp in the form of sheet or thin layer and runs to the end of the conveyor belt. The discharge device is provided with a rotary scraper to scrape the material on the conveyor belt. The scraped material enters the material hopper of the discharge device. The material hopper is provided with a pre-crushing mechanism to crush the sheet material by the relative rotation of the crushing rollers to obtain granular medicinal material. The granular medicinal material is discharged through the discharge valve at the bottom of the material hopper and enters the collection container.

7. The method for preparing a traditional Chinese medicine ointment containing deer tendon powder and deer tortoise shell powder according to claim 6, characterized in that: In S2, the mixture is crushed by putting the granular medicinal material into the vibrating feeder. The vibrating feeder uniformly and continuously transports the granular medicinal material to the fluidized bed jet mill. The fluidized bed jet mill generates high-speed airflow through the supersonic nozzle. The granular medicinal material is crushed by mutual collision and friction in the crushing chamber under the action of the airflow. The fine powder generated by crushing rises with the airflow. The coarse particles return to the crushing area under the action of centrifugal force to continue crushing, realizing high-efficiency and low-temperature crushing and avoiding degradation of heat-sensitive components.

8. The method for preparing a traditional Chinese medicine ointment containing deer tendon powder and deer tortoise shell powder according to claim 7, characterized in that: The superfine medicinal powder from the jet mill enters the high-speed mixing modifier with the airflow. The powder rotates at high speed in the high-speed mixing modifier. The central control system starts the micro-metering pump to uniformly spray the pre-prepared hydrophobic modifier to the powder flow rotating at high speed after atomization by the precision nozzle. Under high-speed stirring, the powder particles and the atomized modifier fully contact. The modifier molecules physically adsorb or chemically bond on the surface of the particles to form a hydrophobic film. This process changes the originally hydrophilic surface of the traditional Chinese medicine powder into hydrophobic, significantly reduces its surface energy and agglomeration tendency, so that the powder can be uniformly distributed in the vaseline. The modified powder enters the cyclone separator. Most of the powder is collected. The fine powder carried by the tail gas is further captured by the pulse back-blowing bag-type dust collector. The collected modified powder is sent to the screening system through airtight pipeline.

9. The method for preparing a traditional Chinese medicine ointment containing deer tendon powder and deer tortoise shell powder according to claim 8, characterized in that: When the mixture is sieved in S2, the medicine powder first falls into the feeding buffer bin when entering the sieving system. The weight sensor at the bottom of the buffer bin detects that the material reaches the set amount, and the central control system starts the vibrating feeder. The vibrating feeder sends the medicine powder uniformly and continuously into the feeding port of the circular vibrating screen at a set frequency and amplitude. After the medicine powder enters the screening machine, it makes three-dimensional elliptical motion under the drive of the eccentric vibrating motor. The material quickly disperses and jumps on the screen surface. The particles smaller than the screen hole quickly pass through the screen. The particles larger than the screen hole move towards the discharge port. The screen is provided with a bouncing ball which continuously jumps under the screen and hits the screen to prevent fine medicine powder from blocking the screen hole.

10. The method for preparing a traditional Chinese medicine ointment containing deer tendon powder and deer tortoise shell powder according to claim 9, characterized in that: The qualified fine powder is conveyed to the medicine powder feeding port of the ointment mixing tank. The melted petrolatum and beeswax are also conveyed into the ointment mixing tank. The mixing structure inside the ointment mixing tank mixes the fine powder, petrolatum and beeswax to obtain the finished traditional Chinese medicine ointment. The screened particles enter the recycling pipeline and are directly conveyed back to the jet mill for regrinding, realizing material recycling.

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