Health-preserving compound preparation based on visceral organs of deer as well as preparation method and application of health-preserving compound preparation

Abstract

The invention discloses a health-preserving compound preparation based on deer viscera as well as a preparation method and application thereof, and the health-preserving compound preparation comprises the following raw materials in parts by weight: 25-35 parts of deer heart blood freeze-dried powder, 20-30 parts of deer bone collagen peptide powder, 25-50 parts of deer viscera superfine powder and 5-10 parts of auxiliary materials, the superfine powder of the deer viscera is a mixture of three or more of the following raw materials: superfine powder of a deer heart extract, superfine powder of a deer liver extract, superfine powder of a deer kidney extract, superfine powder of a deer spleen extract and superfine powder of a deer lung extract. The problems that existing deer-derived products are single in raw material, unreasonable in compatibility, serious in thermal damage in the preparation process, low in bioavailability, limited in function dimension and the like are solved.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of traditional Chinese medicine preparation, in particular to a health composite preparation based on deer viscera and a preparation method and application thereof. BACKGROUND

[0002] With the acceleration of modern life pace and the intensification of population aging, traditional Chinese medicine food homology products are increasingly concerned. Deer-derived medicinal materials, as traditional precious tonics, are widely used in traditional Chinese medicinal materials and have the effects of conditioning and health care. The common deer-derived preparations on the market mainly include single-component or simply combined products such as deer antler tablet, deer blood powder, and deer fetus cream. For example, Chinese Patent No. 202311149258.3, a deer antler extract, deer antler freeze-dried powder, and deer antler oral liquid and a preparation method thereof, mixes fresh deer antler with fresh ginger, adds an extraction agent, and then sequentially soaks, grinds, ultrasonically extracts, separates solid and liquid, filters, and prepares a deer antler extract.

[0003] Deer blood is rich in protein, amino acids, trace elements, and a small amount of hormone substances, and has certain nutritional supplement and metabolic promotion effects. Deer organs such as heart, liver, kidney, spleen, and lung, as animal tissues, contain rich protein, vitamins, and minerals, and can be used as a source of nutrition. Deer bones mainly contain collagen, calcium, phosphorus, and bone morphogenetic protein, which are beneficial to bone health and repair.

[0004] At the same time, traditional Chinese medicine pills are mostly made by high-temperature honeying or drying processes, which leads to the inactivation of heat-sensitive nutrients and seriously affects the biological efficacy of the products. Although low-temperature drying technology has been applied to some health products, there is no report on the systematic low-temperature whole-chain preparation process of deer whole-organ composite preparations.

[0005] In summary, the existing deer-derived products generally have the problems of single raw material, unreasonable combination, severe thermal damage in the preparation process, low bioavailability, and limited functional dimension. Therefore, there is an urgent need to develop a new deer-derived composite preparation based on the combination of multiple organs and the low-temperature whole-chain process. SUMMARY

[0006] The present application provides a health composite preparation based on deer viscera and a preparation method and application thereof, which solves the problems of single raw material, unreasonable combination, severe thermal damage in the preparation process, low bioavailability, and limited functional dimension of the existing deer-derived products.

[0007] To achieve the above-mentioned purpose, the present application provides the following technical solution: a health composite preparation based on deer viscera, comprising the following raw materials in parts by weight: 25-35 parts of deer heart blood freeze-dried powder, 20-30 parts of deer bone collagen peptide powder, 25-50 parts of deer internal organ ultrafine powder, and 5-10 parts of auxiliary materials.

[0008] As a kind of health composite preparation based on deer viscera of the present application, the deer internal organs ultrafine powder is the mixture of three or more of the following raw materials: deer heart extract ultrafine powder, deer liver extract ultrafine powder, deer kidney extract ultrafine powder, deer spleen extract ultrafine powder, deer lung extract ultrafine powder.

[0009] As a kind of health composite preparation based on deer viscera of the present application, the auxiliary materials include one or more of the following: rhizoma polygonati, ganoderma lucidum, medlar, radix scrophulariae, dioscorea and raw land.

[0010] A preparation method of a health composite preparation based on deer viscera, comprising the following steps:

[0011] S1, viscera pretreatment, after cleaning the fresh deer heart, deer liver, deer kidney, deer spleen and deer lung viscera, put them into liquid nitrogen at-196℃ for quick freezing for 30min, realize cell-level freezing, prevent the degradation of active ingredients, after freezing, send them into the ultrafine grinding system, and grind them under low temperature protection, to obtain the ultrafine powder of each viscera, the particle size of the ultrafine powder is ≤5μm;

[0012] S2, directional enzymolysis, deer bone collagen peptide powder is obtained by enzymolysis treatment of deer bone, and deer kidney extract ultrafine powder is obtained by enzymolysis treatment of deer kidney;

[0013] S3, active preparation of deer heart blood freeze-dried powder, after removing blood cells by centrifugation of fresh deer heart blood, collect the plasma components, and prepare deer heart blood freeze-dried powder by freeze-drying technology;

[0014] S4, traditional processing and treatment of traditional Chinese medicine auxiliary materials, process the processing technology of rhizoma polygonati, ganoderma lucidum, medlar, radix scrophulariae, dioscorea and raw land;

[0015] S5, mixing and granulation, according to the proportion, put deer heart blood freeze-dried powder, deer bone collagen peptide powder, deer internal organs ultrafine powder and traditional Chinese medicine auxiliary material ultrafine powder into three-dimensional mixing machine, mix at low speed for 30min, ensure uniformity, according to the needs of dosage form, select direct compression, capsule or add appropriate amount of binder for wet granulation, and after drying, granulate;

[0016] S6, quality inspection and packaging, after preparation, the finished product is detected in whole, including: active ingredient content, microbial limit, heavy metal, particle size distribution and moisture content detection, after inspection, sealed packaging is carried out by using aluminum foil bag or capsule bottle.

[0017] As a kind of preparation method of the health composite preparation based on deer viscera of the present application, preferably, the ultrafine grinding system in S1 includes a cryogenic jet mill and an inert gas circulation protection system, the frozen viscera is fed into the cryogenic jet mill, the inert gas circulation protection system injects high-pressure inert gas into the grinding cavity of the cryogenic jet mill to form supersonic airflow, the material is brought into the grinding zone by the airflow and is broken under the action of high-speed collision and shearing, and liquid nitrogen is continuously injected into the grinding cavity in a small amount during the breaking process to maintain the temperature of the cavity below-100 DEG C to prevent the material from softening or sticking to the wall, and the micro powder after grinding is brought into the turbine air classifier for secondary grinding.

[0018] As a kind of preparation method of the health composite preparation based on deer viscera of the present application, preferably, the particles after secondary grinding are fed into the collection system, and the particles larger than 5 μm are returned to the grinding zone for continuous grinding after filtration by the collection system, and the fine powder ≤5 μm is fed into the collection system, the collection system includes a cyclone separator and a bag filter, the qualified micro powder is first fed into the cyclone separator, the cyclone separator grades the particles of different sizes, the oversized particles are returned to the grinding cavity, and the qualified particles are fed into the bag filter for secondary filtration, the ultrafine powder after secondary filtration is discharged through a low-temperature discharge valve, immediately packed into an aluminum foil moisture-proof bag, sealed and stored below-20 DEG C.

[0019] As a kind of preparation method of the health composite preparation based on deer viscera of the present application, preferably, the complex protease in S2 includes papain and pancreatin, the ratio of papain to pancreatin is 3:1, and the ratio of complex protease to suspension is 100:2-3.

[0020] As a kind of preparation method of the health composite preparation based on deer viscera of the present application, preferably, when the deer bone is subjected to enzymatic hydrolysis in S2, clean deer bone raw material is taken, and after defatting and demineralization treatment, deionized water is added to prepare a suspension, the pH is adjusted to 6.5-7.0, the temperature is controlled at 50-55 DEG C, the complex protease is added after 4-6 hours of enzymatic hydrolysis, the temperature is raised to 90 DEG C to inactivate the enzyme for 10 minutes after the enzymatic hydrolysis is completed, the supernatant is taken by centrifugation, and the deer bone collagen peptide powder is obtained by concentration and drying.

[0021] As a kind of preparation method of the health composite preparation based on deer viscera of the present application, preferably, when the deer kidney is subjected to enzymatic hydrolysis in S2, deionized water is added to the deer kidney ultrafine powder to prepare a suspension, the pH is adjusted to 5.0-6.0, the temperature is controlled at 45-50 DEG C, the complex protease is added after 4-6 hours of enzymatic hydrolysis, the temperature is raised to 90 DEG C to inactivate the enzyme for 10 minutes after the enzymatic hydrolysis is completed, the supernatant is taken by centrifugation, and the deer kidney extract ultrafine powder is obtained by concentration and drying.

[0022] As a preparation method of the health composite preparation based on deer viscera of the present application is preferably, in S3, when the deer blood is freeze-dried, the deer blood is put into the freezing cavity of the ultra-low temperature freeze-drying machine, the deer blood is pre-frozen first, the pre-freezing temperature is-40 to-50℃, the blood plasma is completely frozen into solid ice crystals, then the vacuum system is started, the cavity pressure is reduced to 10-30 Pa, the ice is directly sublimated by slowly heating to remove the water in the deer blood, after the freeze-drying is finished, the vacuum is broken by introducing sterile nitrogen or dry air, the freeze-dried cake is quickly taken out in the clean room, is crushed or directly crushed, then is screened, is passed through 80-100 mesh screen, the fine deer heart blood freeze-dried powder is obtained.

[0023] As a preparation method of the health composite preparation based on deer viscera of the present application is preferably, the processing technology in S4 includes nine steaming and nine drying, wine roasting, honey roasting and vinegar preparation, the drug property and effective components are maximized to be preserved, after the processing is completed, is dried, is super-micro-crushed to the particle size≤10μm, is standby.

[0024] The application of a health composite preparation based on deer viscera, the health composite preparation based on deer viscera is applied to Chinese patent medicines, functional foods, health foods or nutritional supplements.

[0025] Compared with the prior art, the present application has the following beneficial effects:

[0026] 1、The invention is composed of three or more organ extracts, and the organ extracts are deer heart, deer liver, deer kidney, deer spleen and deer lung, realizing whole organ nutritional support, which helps to improve iron deficiency anemia and support liver metabolism, deer kidney tonifying kidney and essence, regulating endocrine, deer spleen and deer lung respectively corresponding to digestive immune and respiratory system function support, multiple organ synergistic effect, which helps to systemically regulate cardiovascular, immune, metabolism, respiratory and reproductive system, at the same time, the medicinal and edible homologous traditional Chinese medicine such as polygonatum, ganoderma lucidum, medlar, radix scrophulariae, dioscorea, and radix rehmanniae are selected as adjuvants, among which ganoderma lucidum, polygonatum and medlar can enhance immunity, antioxidant and anti-fatigue, dioscorea and radix rehmanniae can invigorate the spleen and nourish yin, radix scrophulariae can clear heat and detoxify, which can balance the warm and dry nature of deer animal tissue together, improve the safety and tolerance of the formula, the synergistic effect of plant polysaccharides, saponins and animal active peptides can enhance the overall anti-aging and anti-stress ability, the activity index and process parameters of each raw material are clear, which is beneficial to realize standardized and quantifiable quality control from source to finished product, ensure the consistency and stability between batches, the whole formula can provide nutritional support for users through the synergistic effect of deer heart blood, deer bone collagen peptide and deer kidney extract, combined with deer liver ferritin and heart blood active ingredients to improve deficiency of both qi and blood, improve oxygen transport and energy metabolism capacity, build a complex system of animal source active protein and plant source functional factor, in summary, the technology has the advantages of high efficiency absorption, multi-target synergistic effect, scientific compatibility, quality controllable, clear function, etc., which is suitable for various health needs such as anti-fatigue, enhancing immunity, improving sub-health, delaying aging, bone and joint maintenance and postoperative rehabilitation.

[0027] 2、The invention realizes the deep integration of traditional Chinese medicine concept and modern biological active ingredient extraction technology through scientific proportioning and key process parameter control, and the set multiple quality control indexes significantly improve the bioavailability, functional stability and synergistic effect of the product, the deer bone collagen peptide powder has a molecular weight of less than or equal to 3000 Da, which ensures that the small molecular peptides are more easily absorbed by the intestinal tract, effectively promoting the repair and regeneration of connective tissues such as bone, joint and skin, the deer internal organs adopt ultrafine grinding and low-temperature enzymolysis technology to maximize the structural integrity of organ-specific proteins, enzymes and active factors under suitable conditions, improve their physiological activity and absorption rate, the deer heart blood freeze-dried powder has a thrombin activity of more than or equal to 1500 IU / g, which provides high active ingredients to promote microcirculation and regulate blood function, and has potential support for improving blood supply to heart and brain and relieving fatigue. BRIEF DESCRIPTION OF DRAWINGS

[0028] Figure 1 The figure is a preparation flowchart of the invention. DETAILED DESCRIPTION

[0029] Example 1

[0030] A health preserving composite preparation based on deer viscera, comprising the following raw materials in parts by weight: 25-35 parts of deer heart blood freeze-dried powder, 20-30 parts of deer bone collagen peptide powder, 25-50 parts of deer internal organ ultrafine powder, and 5-10 parts of auxiliary materials.

[0031] Further, the deer internal organ ultrafine powder is a mixture of three or more of the following: deer heart extract ultrafine powder, deer liver extract ultrafine powder, deer kidney extract ultrafine powder, deer spleen extract ultrafine powder, and deer lung extract ultrafine powder.

[0032] Further, the auxiliary materials include one or more of Rhizoma Polygonati, Ganoderma lucidum, Lycium barbarum, Scrophularia ningpoensis, Radix Paeoniae Alba, and Radix Rehmanniae.

[0033] Further, the deer heart blood freeze-dried powder has a thrombin activity of ≥1500 IU / g.

[0034] Further, the deer bone collagen peptide powder has a molecular weight of ≤3000 Da.

[0035] Further, the deer liver extract ultrafine powder has a ferritin content of ≥8 mg / g.

[0036] Further, the deer kidney extract ultrafine powder is subjected to low-temperature enzymatic hydrolysis at a pH of 5.0-6.0.

[0037] The health preserving composite preparation based on deer viscera realizes the deep integration of traditional Chinese medicine concepts and modern bioactive ingredient extraction technology through scientific proportioning and key process parameter control. The multiple quality control indicators set by the preparation significantly improve the bioavailability, functional stability, and synergistic effect of the product. The deer bone collagen peptide powder has a molecular weight of ≤3000 Da, ensuring that small molecule peptides are more easily absorbed by the intestinal tract, effectively promoting the repair and regeneration of connective tissues such as bones, joints, and skin. The deer internal organs are subjected to ultrafine grinding and low-temperature enzymatic hydrolysis, which maximizes the structural integrity of organ-specific proteins, enzymes, and active factors under suitable conditions, improving their physiological activity and absorption rate. The deer heart blood freeze-dried powder has a thrombin activity of ≥1500 IU / g, providing high-activity ingredients to promote microcirculation, regulate blood function, and potentially support the improvement of heart and brain blood supply and the relief of fatigue.

[0038] The deer internal organ ultrafine powder in the formula is composed of extracts from three or more organs, and the organ extracts are deer heart, deer liver, deer kidney, deer spleen and deer lung, realizing whole organ nutritional support, which helps to improve iron deficiency anemia and support liver metabolism, deer kidney tonifying kidney and essence, regulating endocrine, deer spleen and deer lung respectively corresponding to digestive immune and respiratory system function support, multiple organ synergistic effect, which helps to systemically regulate cardiovascular, immune, metabolism, respiratory and reproductive system, at the same time, the medicinal and edible herbs such as huangji, lingzhi, gosberry, huangqi, shanyao and shengdi are selected as adjuvants, among which lingzhi, huangji and gosberry can enhance immunity, antioxidant and anti-fatigue, shanyao and shengdi can invigorate the spleen and nourish yin, huangqi can clear heat and detoxify, which can balance the warm and dry nature of deer animal tissue together, improve the safety and tolerance of the formula, the synergistic effect of plant polysaccharides, saponins and animal active peptides can enhance the overall anti-aging and anti-stress ability, and the active index and process parameters of each raw material are clear, which is beneficial to realize standardized and quantifiable quality control from source to finished product, ensure the consistency and stability between batches, and the whole formula can provide nutritional support to users through the synergistic effect of deer heart blood, deer bone collagen peptide and deer kidney extract, combined with deer liver ferritin and heart active ingredients to improve deficiency of both qi and blood, improve oxygen transport and energy metabolism capacity, and build a complex system of animal source active protein and plant source functional factor, in summary, the technology has the advantages of high efficiency absorption, multi-target synergistic effect, scientific compatibility, quality controllable, clear function, etc., which is suitable for various health needs such as anti-fatigue, enhancing immunity, improving sub-health, delaying aging, bone joint maintenance and postoperative rehabilitation.

[0039] Example 2

[0040] Please refer to Figure 1 A preparation method of a health composite preparation based on deer organs, comprising the following steps:

[0041] S1, organ pretreatment, after cleaning the fresh deer heart, deer liver, deer kidney, deer spleen and deer lung organs, put them into liquid nitrogen at-196℃ for 30min, realize cell-level freezing, prevent degradation of active ingredients, after freezing, put them into the ultrafine grinding system, grind under low temperature protection, prepare ultrafine powder of each organ, the particle size of the ultrafine powder is ≤5μm;

[0042] S2, directional enzymolysis, deer bone collagen peptide powder is obtained by enzymolysis treatment of deer bone, and deer kidney extract ultrafine powder is obtained by enzymolysis treatment of deer kidney;

[0043] S3, active preparation of deer heart blood freeze-dried powder, after removing blood cells by centrifugation, collect the plasma components of fresh deer heart blood, and prepare deer heart blood freeze-dried powder by freeze-drying technology;

[0044] S4, traditional processing and treatment of medicinal adjuvants, process the processing technology of huangji, lingzhi, gosberry, huangqi, shanyao and shengdi;

[0045] S5, mixing and granulation, according to the proportion, the deer heart blood freeze-dried powder, deer bone collagen peptide powder, deer internal organs ultrafine powder and traditional Chinese medicine auxiliary material ultrafine powder are put into a three-dimensional mixer, mixed at low speed for 30 minutes to ensure uniformity, according to the needs of the dosage form, direct compression, capsule or adding appropriate amount of binder for wet granulation, drying and granulating;

[0046] S6, quality inspection and packaging, after preparation, the finished product is detected, including: active ingredient content, microbial limit, heavy metal, particle size distribution and moisture content detection, after inspection, aluminum foil bag or capsule bottle is used for sealing and packaging.

[0047] The ultrafine grinding system in S1 includes a low-temperature jet mill and an inert gas circulation protection system. The frozen organs enter the low-temperature jet mill, the inert gas circulation protection system injects high-pressure inert gas into the grinding cavity of the low-temperature jet mill to form a supersonic gas flow, the material is brought into the grinding area by the gas flow and is broken down under the action of high-speed collision and shearing. Liquid nitrogen is continuously injected into the grinding cavity during the breaking process to maintain the temperature of the cavity below -100°C, preventing the material from softening or sticking to the wall. The ground powder enters the turbine air classifier for secondary grinding.

[0048] The particles after secondary grinding enter the collection system, and the particles larger than 5 μm are returned to the grinding area for further grinding, and the fine powder ≤5 μm enters the collection system. The collection system includes a cyclone separator and a bag filter. The qualified fine powder first enters the cyclone separator, which classifies particles of different sizes. The oversized particles are returned to the grinding cavity, and the qualified particles enter the bag filter for secondary filtration. The ultrafine powder after secondary filtration is discharged through a low-temperature discharge valve, immediately packed into an aluminum foil moisture-proof bag, sealed and stored at -20°C or below.

[0049] The complex protease in S2 includes papain and trypsin, and the ratio of papain to trypsin is 3:1. The ratio of complex protease to suspension is 100:2-3.

[0050] During the enzymatic treatment of deer bone in S2, clean deer bone raw materials are taken, defatted and demineralized, and then added to deionized water to form a suspension. The pH is adjusted to 6.5-7.0, the temperature is controlled at 50-55°C, and the complex protease is added for 4-6 hours of enzymatic hydrolysis. After the enzymatic hydrolysis is completed, the temperature is raised to 90°C to inactivate the enzyme for 10 minutes. The supernatant is obtained by centrifugation, concentrated and dried to obtain deer bone collagen peptide powder.

[0051] In S2, when enzymatically hydrolyzing deer kidney, deionized water is added to the deer kidney ultrafine powder to form a suspension, the pH is adjusted to 5.0–6.0, the temperature is controlled at 45–50℃, a complex protease is added and enzymatic hydrolysis is carried out for 4–6 hours. After the enzymatic hydrolysis is completed, the temperature is raised to 90℃ to inactivate the enzyme for 10 minutes, the supernatant is collected by centrifugation, and the deer kidney extract ultrafine powder is obtained by concentration and drying.

[0052] In S3, when freeze-drying deer blood, the deer blood is placed in the freezing chamber of an ultra-low temperature freeze dryer and pre-frozen at a temperature of -40 to -50°C to completely freeze the plasma into solid ice crystals. Then, the vacuum system is activated to reduce the chamber pressure to 10–30 Pa. The water in the deer blood is removed by slowly raising the temperature to allow the ice to sublimate directly. After freeze-drying, sterile nitrogen or dry air is introduced to break the vacuum. The freeze-dried cake is then quickly removed in a clean room, crushed or directly pressed, and then screened through an 80–100 mesh sieve to obtain fine freeze-dried deer heart blood powder.

[0053] The processing techniques in S4 include nine steaming and nine sun-drying, wine-processing, honey-processing, and vinegar-processing, which maximize the preservation of medicinal properties and active ingredients. After processing, the herbs are dried and ultra-finely pulverized to a particle size ≤10μm for later use.

[0054] Through systematic and refined process design, the extraction efficiency and bioavailability of active ingredients from deer organs have been significantly improved. In the organ pretreatment stage, -196℃ liquid nitrogen quick-freezing combined with low-temperature airflow pulverization technology is used to achieve cell-level freezing and ultra-fine pulverization, effectively preventing the degradation of heat-sensitive components, enhancing tissue fragmentation, and improving subsequent enzymatic hydrolysis and absorption efficiency. An inert gas protection system avoids oxidation reactions and ensures material purity. The targeted enzymatic hydrolysis process precisely controls parameters according to the characteristics of different tissues. Deer bones are enzymatically hydrolyzed at pH 6.5–7.0 and 50–55℃, combined with defatting and demineralization pretreatment, to fully release collagen and convert it into small molecule peptides, which are conducive to intestinal absorption. Deer kidneys are enzymatically hydrolyzed under mild conditions of pH 5.0–6.0 and 45–50℃, retaining their endocrine active factors and functional peptides, and enhancing their physiological effects of "tonifying the kidney and replenishing essence". The freeze-drying process strictly controls the pre-freezing temperature and vacuum sublimation process, so that the retention rate of active ingredients such as thrombin in deer heart blood plasma is as high as 95%, ensuring the stability of its functions of promoting circulation and replenishing qi and blood.

[0055] This solution integrates traditional Chinese medicine processing wisdom with modern formulation technology to further enhance overall efficacy and safety. The Polygonatum sibiricum undergoes authentic processing methods such as nine steaming and nine sun-drying processes, wine-processing of Lycium barbarum, honey-processing of Ganoderma lucidum, and vinegar-processing of Rehmannia glutinosa. This not only improves the dissolution rate of active ingredients but also harmonizes the medicinal properties and balances the warming and drying nature of deer tissues. Combined with ultra-fine pulverization to ≤10μm, the bioavailability of the Chinese medicine excipients is improved. Finally, through three-dimensional mixing and standardized granulation, a multi-component uniform compound is achieved. The finished product undergoes comprehensive quality inspection to ensure controllable quality. The overall process achieves an organic unity of "low-temperature preservation, precise enzymatic hydrolysis, ancient methods for enhanced efficacy, and modern molding." It is suitable for developing highly active, high-quality functional health products for anti-fatigue, immune enhancement, sub-health improvement, and post-operative recovery, possessing both scientific validity, safety, and industrial feasibility.

[0056] Example 3

[0057] Application of a health-preserving compound preparation based on deer organs, which can be used in traditional Chinese medicine, functional foods, health foods or nutritional supplements.

[0058] The above are merely preferred embodiments of the present invention and are not intended to limit the present invention. Any modifications, equivalent substitutions, and improvements made within the spirit and principles of the present invention should be included within the protection scope of the present invention.

Claims

1. A health-preserving compound preparation based on deer organs, characterized in that, The ingredients include the following parts by weight: 25-35 parts of freeze-dried deer heart blood powder, 20-30 parts of deer bone collagen peptide powder, 25-50 parts of ultrafine deer viscera powder, and 5-10 parts of excipients. The deer viscera ultrafine powder is a mixture of three or more of the following raw materials: deer heart extract ultrafine powder, deer liver extract ultrafine powder, deer kidney extract ultrafine powder, deer spleen extract ultrafine powder, and deer lung extract ultrafine powder. The excipients include one or more of the following: Polygonatum sibiricum, Ganoderma lucidum, Lycium barbarum, Scutellaria baicalensis, Dioscorea opposita, and Rehmannia glutinosa.

2. A method for preparing a health-preserving compound preparation based on deer organs, characterized in that, Includes the following steps: S1. Organ pretreatment: After cleaning and removing impurities from fresh deer heart, liver, kidney, spleen and lungs, they are rapidly frozen in liquid nitrogen at -196℃ for 30 minutes to achieve cell-level freezing and prevent degradation of active ingredients. After freezing, they are sent to an ultra-micro pulverization system and pulverized under low temperature protection to obtain ultra-micro powder of each organ with a particle size ≤5μm. S2. Targeted enzymatic hydrolysis: Deer bones are enzymatically hydrolyzed to obtain deer bone collagen peptide powder, and deer kidneys are enzymatically hydrolyzed to obtain deer kidney extract ultrafine powder. S3. Preparation of active deer heart blood freeze-dried powder: After centrifuging fresh deer heart blood to remove blood cells, plasma components are collected and freeze-dried powder is prepared using freeze-drying technology. S4. Traditional processing and treatment of Chinese medicinal materials, including processing of Polygonatum sibiricum, Ganoderma lucidum, Lycium barbarum, Scutellaria baicalensis, Dioscorea opposita and Rehmannia glutinosa. S5. Mixing and granulation: According to the formula, put the freeze-dried deer heart blood powder, deer bone collagen peptide powder, deer viscera ultrafine powder and traditional Chinese medicine excipient ultrafine powder into a three-dimensional mixer and mix at low speed for 30 minutes to ensure uniformity. Depending on the dosage form, choose to directly compress tablets or fill capsules, or add an appropriate amount of binder for wet granulation, and then granulate after drying. S6. Quality Inspection and Packaging: After preparation, the finished product undergoes comprehensive testing, including: active ingredient content, microbial limits, heavy metals, particle size distribution, and moisture content. After passing the inspection, the product is sealed and packaged in aluminum foil bags or capsule bottles.

3. The method for preparing a health-preserving compound preparation based on deer organs according to claim 2, characterized in that: The ultrafine pulverization system in S1 includes a cryogenic airflow pulverizer and an inert gas circulation protection system. After freezing, the organs enter the cryogenic airflow pulverizer. The inert gas circulation protection system injects high-pressure inert gas into the pulverizing chamber of the cryogenic airflow pulverizer to form a supersonic airflow. The material is carried into the pulverizing zone by the airflow and is crushed under high-speed collision and shearing. During the crushing process, liquid nitrogen is continuously injected in small amounts into the pulverizing chamber to maintain the chamber temperature below -100℃ and prevent the material from softening or sticking to the wall. The pulverized powder enters the turbine air classifier for secondary pulverization with the airflow.

4. The method for preparing a health-preserving compound preparation based on deer organs according to claim 3, characterized in that: After secondary crushing, the particles enter the collection system. After filtration by the collection system, particles larger than 5μm are returned to the crushing zone for further crushing, while fine powder ≤5μm enters the collection system, which includes a cyclone separator and a bag filter. Qualified micro powder first enters the cyclone separator, which classifies particles of different sizes. Oversized particles are returned to the crushing chamber, while qualified particles enter the bag filter for secondary filtration. The ultrafine powder after secondary filtration is discharged through a low-temperature discharge valve, immediately packed into aluminum foil moisture-proof bags, sealed, and stored below -20℃.

5. The method for preparing a health-preserving compound preparation based on deer organs according to claim 4, characterized in that: The complex protease in S2 includes papain and pancreatin, with a ratio of 3:1 between papain and pancreatin, and a ratio of 100:2-3 between the complex protease and the suspension.

6. The method for preparing a health-preserving compound preparation based on deer organs according to claim 5, characterized in that: In S2, when enzymatically hydrolyzing deer bone, clean deer bone raw material is taken, and after defatting and demineralization, deionized water is added to form a suspension. The pH is adjusted to 6.5–7.0, the temperature is controlled at 50–55℃, a complex protease is added, and enzymatic hydrolysis is carried out for 4–6 hours. After the enzymatic hydrolysis is completed, the temperature is raised to 90℃ to inactivate the enzyme for 10 minutes. The supernatant is collected by centrifugation, and after concentration and drying, deer bone collagen peptide powder is obtained.

7. The method for preparing a health-preserving compound preparation based on deer organs according to claim 6, characterized in that: In S2, when enzymatically hydrolyzing deer kidney, deionized water is added to the deer kidney ultrafine powder to form a suspension, the pH is adjusted to 5.0–6.0, the temperature is controlled at 45–50℃, a complex protease is added and enzymatic hydrolysis is carried out for 4–6 hours. After the enzymatic hydrolysis is completed, the temperature is raised to 90℃ to inactivate the enzyme for 10 minutes, the supernatant is collected by centrifugation, and the deer kidney extract ultrafine powder is obtained by concentration and drying.

8. The method for preparing a health-preserving compound preparation based on deer organs according to claim 7, characterized in that: In S3, when freeze-drying deer blood, the deer blood is placed in the freezing chamber of an ultra-low temperature freeze dryer and pre-frozen at a temperature of -40 to -50°C to completely freeze the plasma into solid ice crystals. Then, the vacuum system is activated to reduce the chamber pressure to 10–30 Pa. The water in the deer blood is removed by slowly raising the temperature to allow the ice to sublimate directly. After freeze-drying, sterile nitrogen or dry air is introduced to break the vacuum. The freeze-dried cake is then quickly removed in a clean room, crushed or directly pressed, and then screened through an 80–100 mesh sieve to obtain fine freeze-dried deer heart blood powder.

9. The method for preparing a health-preserving compound preparation based on deer organs according to claim 8, characterized in that: The processing techniques in S4 include nine steaming and nine sun-drying, wine-processing, honey-processing, and vinegar-processing, which maximize the preservation of medicinal properties and active ingredients. After processing, the herbs are dried and ultra-finely pulverized to a particle size ≤10μm for later use.

10. The application of a health-preserving compound preparation based on deer organs, characterized in that: Health-preserving compound preparations based on deer organs can be used in traditional Chinese medicine, functional foods, health foods, or nutritional supplements.

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