Absorption type glass slide separation device capable of preventing cross contamination
By combining a ring suction cup and an atomizing nozzle, the problem of frequent slide replacement and cross-contamination in multi-sample testing is solved, achieving efficient slide separation and automatic humidity control, thus improving experimental efficiency and accuracy.
Patent Information
- Application Number
- CN202511488452.3
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-10-17
- Publication Date
- 2026-01-16
AI Technical Summary
In clinical testing, frequent slide changes are required when testing multiple samples, which affects experimental efficiency and can easily cause cross-contamination between samples, affecting experimental accuracy.
An adsorption-type slide separator that prevents cross-contamination is used. A single slide is divided into multiple independent areas by a ring suction cup. An air wall is formed by an air pump and atomizing nozzle to block external dust. The ring suction cup physically isolates the sample. Combined with an automatic humidification system to regulate humidity, the sample mixing and breakage are prevented.
This method enables simultaneous detection of multiple samples on the same slide, improving experimental efficiency, reducing sample contamination and breakage, and ensuring experimental accuracy.
Smart Images
Figure CN121348554A_ABST
Abstract
Description
Technical Field
[0001] This invention relates to the field of clinical testing technology, specifically to an adsorption-type slide separator that prevents cross-contamination. Background Technology
[0002] In experimental research in biology, medicine, and other fields, glass slides are commonly used experimental instruments to hold samples for observation under microscopes and other equipment. In clinical testing, experiments such as ABO slide blood typing and multi-item microscopic examination of body fluid specimens currently mainly use a single slide, single sample testing protocol. When testing multiple samples, the slides need to be changed frequently, which affects the efficiency of the experiment. To save time and costs, it is often necessary to place multiple samples on a slide for testing. However, it is difficult to place multiple samples in an orderly manner on the same slide at the same time, and sample handling can easily cause contamination between samples, affecting the accuracy of the experimental operation. Summary of the Invention
[0003] The purpose of this invention is to provide an adsorption-type slide separator that prevents cross-contamination, in order to solve the problem mentioned in the background art that in clinical testing, such as ABO slide blood typing and multi-item microscopic examination of body fluid specimens, the current experimental scheme mainly adopts single slide single sample testing. When testing multiple samples, the slides need to be changed frequently, which affects the experimental efficiency. In order to save time and cost, it is often necessary to place multiple samples on the slide for testing. However, it is difficult to place multiple samples in an orderly manner on the same slide for simultaneous testing, and sample contamination is easily caused during sample handling, affecting the accuracy of the experimental operation.
[0004] To achieve the above objectives, the present invention provides the following technical solution: an adsorption-type glass slide separation device for preventing cross-contamination, comprising a base, a double-lobed butterfly valve, a separation component provided on the top of the base, a homogenization component provided on the top of the base, and a humidification component provided on the top of the base. The segmentation component includes an upper cover plate, and multiple annular suction cups are fixedly connected to one side of the outer surface of the upper cover plate. An air pump is fixedly connected to one side of the outer surface of the base, and an air inlet pipe is provided inside the air pump. The side of the air inlet pipe away from the air pump is located inside the air inlet pipe. Two sets of atomizing nozzles are provided inside the upper cover plate. The homogenizing component includes a reciprocating screw rotatably embedded inside the base, and the reciprocating screw is connected to a threaded block through a ball nut pair. A fixed base is fixedly connected to the top of the outer surface of the threaded block, and the upper cover plate is rotatably embedded inside the fixed base. The humidification assembly includes a liquid cylinder fixedly connected to the top of the outer surface of the base, and a float plate is slidably embedded inside the liquid cylinder. A liquid delivery pipe is provided inside the liquid cylinder, and a fixing block is fixedly connected to the outer surface of the liquid delivery pipe. A transmission column is rotatably embedded inside the fixing block. The double-leaf butterfly valve is located inside the liquid delivery pipe, and one side of the outer surface of the transmission column is movably connected to the double-leaf butterfly valve.
[0005] Preferably, a limiting rod is fixedly connected to one side of the outer surface of the base, the threaded block is slidably sleeved on the outer surface of the limiting rod in a horizontal direction, and two sets of sliding grooves are provided inside the fixed base.
[0006] Preferably, a drive motor is fixedly connected to one side of the outer surface of the base, and the output shaft of the drive motor is fixedly connected to a reciprocating lead screw.
[0007] Preferably, the air pump has an air outlet pipe inside, and the end of the air outlet pipe away from the air pump is located inside the atomizing nozzle.
[0008] Preferably, a first magnet is fixedly connected to the top of the outer surface of the float plate, and the end of the liquid delivery pipe away from the liquid cylinder is located inside the air outlet pipe.
[0009] Preferably, a fixing rod is fixedly connected to one side of the outer surface of the fixing block, and a fixing frame is fixedly connected to one side of the outer surface of the fixing rod.
[0010] Preferably, a rotating gear is rotatably embedded inside the fixed frame, and a gear plate is slidably embedded in the fixed frame in a horizontal direction. The outer surface of the rotating gear meshes with the gear plate, and one side of the outer surface of the rotating gear is fixedly connected to the transmission column.
[0011] Preferably, a second magnet is fixedly connected to one side of the outer surface of the gear plate, and a return spring is fixedly connected to one side of the outer surface of the second magnet. The end of the return spring away from the second magnet is fixedly connected to the fixing frame.
[0012] Compared with the prior art, the beneficial effects of the present invention are: This invention utilizes a ring-shaped suction cup and a vacuum pump to adsorb glass slides, dividing a single slide into multiple independent regions. This enables simultaneous experiments with multiple samples on a single slide, improving utilization. Simultaneously, the gas discharged from the vacuum pump forms an air wall through an atomizing nozzle, preventing external dust from entering and reducing sample contamination. Furthermore, the uniform negative pressure of the ring-shaped suction cup ensures tight adhesion of the glass slide, preventing slide displacement during experiments and reducing sample breakage caused by slippage. The ring-shaped suction cup also physically isolates different samples, preventing sample mixing and leakage.
[0013] This invention uses an atomizing nozzle to spray around the slide. Through the above technical solution, the annular suction cup adsorbs the slide via a vacuum pump, dividing a single slide into multiple independent areas. This enables simultaneous experiments with multiple samples on one slide, improving utilization. Simultaneously, the gas discharged by the vacuum pump forms an air wall through the atomizing nozzle, preventing external dust from entering and reducing sample contamination. Furthermore, the uniform negative pressure of the annular suction cup tightly adsorbs the slide, preventing slide displacement during experiments and reducing sample breakage due to slippage. Additionally, the annular suction cup partitions the slide, physically isolating different samples to prevent mixing and leakage.
[0014] In this invention, the ionized water in the liquid cylinder evaporates naturally with the ambient humidity. When the water level drops to the threshold, the double-lobed butterfly valve is opened by rotating the gear, and the remaining liquid is sprayed out through the atomizing nozzle to humidify, realizing automatic humidity regulation in response to drying. Furthermore, the air pump pressurizes the atomization to make it finer, avoiding direct dripping. The fine water mist sprayed from the atomizing nozzle combines with the air wall formed by the gas to create a ring-shaped humidified airflow around the glass slide. Attached Figure Description
[0015] Figure 1 This is a schematic diagram of the overall structure of the present invention; Figure 2 This is a schematic diagram of the fixed bottom structure of the present invention; Figure 3 This is a schematic diagram of the upper cover plate structure of the present invention; Figure 4 This is one of the partial structural schematic diagrams of the present invention; Figure 5 This is a partial structural schematic diagram of the present invention; Figure 6 The third part is a schematic diagram of the structure of the present invention.
[0016] In the diagram: 1. Base; 2. Fixed base; 201. Slide groove; 3. Top cover plate; 301. Annular suction cup; 302. Atomizing nozzle; 4. Liquid cylinder; 401. Float plate; 402. First magnet; 5. Air pump; 501. Air inlet pipe; 502. Air outlet pipe; 6. Liquid delivery pipe; 601. Fixing block; 602. Fixing rod; 603. Fixing frame; 604. Rotating gear; 605. Transmission column; 606. Gear plate; 607. Second magnet; 608. Return spring; 7. Double-lobed butterfly valve; 8. Reciprocating screw; 801. Threaded block; 802. Limiting rod; 9. Drive motor. Detailed Implementation
[0017] To make the objectives, technical solutions, and advantages of the embodiments of the present invention clearer, the technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Therefore, the following detailed description of the embodiments of the present invention provided in the accompanying drawings is not intended to limit the scope of the claimed invention, but merely to illustrate selected embodiments of the invention. All other embodiments obtained by those skilled in the art based on the embodiments of the present invention without inventive effort are within the scope of protection of the present invention.
[0018] See Figures 1 to 6 As shown, the present invention provides an adsorption-type slide separator to prevent cross-contamination, including a base 1 and a double-lobed butterfly valve 7. A dividing component, a homogenizing component, and a humidifying component are provided on the top of the base 1. The dividing component includes an upper cover plate 3, and multiple annular suction cups 301 are fixedly connected to one side of the outer surface of the upper cover plate 3. An air pump 5 is fixedly connected to one side of the outer surface of the base 1, and an air inlet pipe 501 is provided inside the air pump 5. The side of the air inlet pipe 501 away from the air pump 5 is located inside the air inlet pipe 501. Two sets of atomizing nozzles 302 are provided inside the upper cover plate 3. An air outlet pipe 502 is provided inside the air pump 5, and the end of the air outlet pipe 502 away from the air pump 5 is located inside the atomizing nozzle 302. See Figures 1 to 5 As shown, the operator inserts the glass slide into the groove 201 within the fixed base 2, then places the upper cover 3 over the glass slide. By activating the vacuum pump 5, the pump draws gas from multiple annular suction cups 301 through the external air intake pipe 501. The negative pressure generated by the multiple annular suction cups 301 adsorbs the slide. The gas drawn from the outside through the air intake pipe 501 and the external air intake pipe 501 is then delivered to multiple atomizing nozzles 302 through the air outlet pipe 502. The atomized gas is sprayed around the slide through the atomizing nozzles 302. Through this technical solution, the annular suction cups 301 draw gas from the external air intake pipe 501. The air pump 5 adsorbs the glass slide, dividing a single glass slide into multiple independent areas, enabling simultaneous experiments with multiple samples on one slide and improving utilization. At the same time, the gas discharged by the air pump 5 forms an air wall through the atomizing nozzle 302, blocking external dust from entering and reducing sample contamination. Meanwhile, the annular suction cup 301 applies uniform negative pressure to tightly adsorb the glass slide, preventing slide displacement during the experiment and reducing sample damage caused by slippage. In addition, the annular suction cup 301 divides the slide into sections, physically isolating different samples to prevent sample mixing and leakage.
[0019] The homogenizing component includes a reciprocating screw 8 rotatably embedded inside the base 1, and the reciprocating screw 8 is connected to a threaded block 801 via a ball nut pair. A fixed base 2 is fixedly connected to the top of the outer surface of the threaded block 801, and the upper cover plate 3 is rotatably embedded inside the fixed base 2. A limit rod 802 is fixedly connected to one side of the outer surface of the base 1, and the threaded block 801 is slidably sleeved on the outer surface of the limit rod 802 in a horizontal direction. Two sets of sliding grooves 201 are provided inside the fixed base 2. A drive motor 9 is fixedly connected to one side of the outer surface of the base 1, and the output shaft of the drive motor 9 is fixedly connected to the reciprocating screw 8. See Figures 3 to 5 As shown, after the slide is fixed, the drive motor 9 is turned on, and the output shaft of the drive motor 9 drives the reciprocating screw 8 to rotate. The rotation of the reciprocating screw 8 drives the short-stroke threaded block 801 to move. The short-stroke reciprocating movement of the threaded block 801 drives the fixed base 2 to move. The movement of the fixed base 2 drives the slide to move. Through the above technical solution, the short-stroke reciprocating motion of the slide breaks the local constraint of the liquid surface tension, allowing the low-viscosity sample to spread smoothly along the plane of the slide, avoiding liquid accumulation or local accumulation at the edges, and avoiding uneven sample distribution. At the same time, the force of the short-stroke shaking is gentle, and the damage to live cells and fragile samples is much less than that of manual violent shaking, reducing experimental errors caused by cell rupture. The slide is fixed by the annular suction cup 301, which provides a stable foundation for the movement of the slide. The uniform spreading through the short-stroke reciprocating motion can make full use of the space divided by the annular suction cup 301, avoid local blanks in the partition, and improve the effectiveness of multiple samples on one slide.
[0020] The humidification assembly includes a liquid cylinder 4 fixedly connected to the top of the outer surface of the base 1, with a float 401 slidably embedded inside the liquid cylinder 4. A liquid delivery pipe 6 is installed inside the liquid cylinder 4, and a fixing block 601 is fixedly connected to the outer surface of the liquid delivery pipe 6. A transmission column 605 is rotatably embedded inside the fixing block 601. A double-leaf butterfly valve 7 is located inside the liquid delivery pipe 6, and one side of the outer surface of the transmission column 605 is movably connected to the double-leaf butterfly valve 7. A first magnet 402 is fixedly connected to the top of the outer surface of the float 401, and the end of the liquid delivery pipe 6 away from the liquid cylinder 4 is located inside the air outlet pipe 502. A fixing rod is fixedly connected to one side of the outer surface of the fixing block 601. 602, and a fixing frame 603 is fixedly connected to one side of the outer surface of the fixing rod 602; a rotating gear 604 is rotatably embedded inside the fixing frame 603, and a gear plate 606 is slidably embedded in the fixing frame 603 in the horizontal direction. The outer surface of the rotating gear 604 meshes with the gear plate 606, and one side of the outer surface of the rotating gear 604 is fixedly connected to the transmission column 605; a second magnet 607 is fixedly connected to one side of the outer surface of the gear plate 606, and a return spring 608 is fixedly connected to one side of the outer surface of the second magnet 607. The end of the return spring 608 away from the second magnet 607 is fixedly connected to the fixing frame 603. See Figures 4 to 6 As shown, the operator adds deionized water into the liquid cylinder 4. During use, when the ambient air humidity is relatively dry, the deionized water in the liquid cylinder 4 will evaporate. When the deionized water evaporates, the liquid level in the liquid cylinder 4 drops, causing the float 401 to move. The movement of the float 401 then moves the first magnet 402. When the first magnet 402 moves close to the second magnet 607, it generates a reaction thrust, pushing the second magnet 607 away from the end of the liquid cylinder 4. The movement of the second magnet 607 then causes the gear plate 606 to slide within the fixed frame 603. The movement of the gear plate 606 then drives the meshing rotating gear 604 to rotate. The rotation of the rotating gear 604... The transmission column 605 drives the double-leaf butterfly valve 7 to open, allowing the remaining ionized water inside the liquid cylinder 4 to be discharged through the liquid delivery pipe 6. The liquid delivery pipe 6 then transports the ionized water to the air outlet pipe 502, and subsequently discharges it through multiple atomizing nozzles 302 in the upper cover plate 3, thereby humidifying the area around the slide. Through the above technical solution, the ionized water in the liquid cylinder 4 evaporates naturally with the ambient humidity. When the water level drops to the threshold, the double-leaf butterfly valve 7 is opened by rotating the gear 604, and the remaining liquid is sprayed out through the atomizing nozzles 302 for humidification, achieving automatic humidity regulation in response to drying. Furthermore, the air pump 5 pressurizes the air to make the atomization finer, avoiding direct dripping. The fine water mist sprayed by the atomizing nozzles 302 combines with the air wall formed by the gas to create a ring-shaped humidified airflow around the glass slide.
[0021] Working principle: The operator inserts the glass slide into the groove 201 inside the fixed base 2, and then puts the upper cover plate 3 on the outside of the glass slide. By turning on the air pump 5, the air pump 5 draws gas from multiple annular suction cups 301 through the outside and the air inlet pipe 501. The negative pressure generated by the multiple annular suction cups 301 adsorbs the slide, and the air pump 5 delivers the gas drawn from the outside through the air inlet pipe 501 to multiple atomizing nozzles 302 through the air outlet pipe 502, and sprays it around the slide.
[0022] After the carrier is fixed, the drive motor 9 is turned on, and the output shaft of the drive motor 9 drives the reciprocating screw 8 to rotate. The rotation of the reciprocating screw 8 drives the short-stroke threaded block 801 to move. The short-stroke reciprocating movement of the threaded block 801 drives the fixed base 2 to move. The movement of the fixed base 2 drives the carrier to move.
[0023] Workers add deionized water into liquid cylinder 4. During use, when the surrounding air humidity is relatively dry, the deionized water in liquid cylinder 4 will evaporate. When the deionized water evaporates, the liquid level in liquid cylinder 4 drops, causing the float 401 to move. The movement of the float 401 then moves the first magnet 402. When the first magnet 402 moves close to the second magnet 607, it generates a reaction force, which pushes the second magnet 607 to move away from the end of liquid cylinder 4. The movement of iron 607 causes the gear plate 606 to slide within the fixed frame 603. The movement of the gear plate 606 causes the meshing rotating gear 604 to rotate. The rotation of the rotating gear 604 causes the double-lobed butterfly valve 7 to open via the transmission column 605. The opening of the double-lobed butterfly valve 7 allows the remaining ionized water inside the liquid cylinder 4 to be discharged through the liquid delivery pipe 6. The ionized water is then transported to the air outlet pipe 502 through the liquid delivery pipe 6 and subsequently discharged through multiple atomizing nozzles 302 in the upper cover plate 3, thereby humidifying the area around the carrier.
[0024] Although embodiments of the invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the appended claims and their equivalents.
Claims
1. An adsorption-type glass slide separator for preventing cross-contamination, comprising a base (1) and a double-lobed butterfly valve (7), characterized in that, The base (1) is provided with a dividing component on the top, a homogenizing component on the top, and a humidifying component on the top. The segmentation component includes an upper cover plate (3), and a plurality of annular suction cups (301) are fixedly connected to one side of the outer surface of the upper cover plate (3). An air pump (5) is fixedly connected to one side of the outer surface of the base (1), and an air inlet pipe (501) is provided inside the air pump (5). The side of the air inlet pipe (501) away from the air pump (5) is located inside the air inlet pipe (501). Two sets of atomizing nozzles (302) are provided inside the upper cover plate (3). The homogenizing component includes a reciprocating screw (8) rotatably embedded inside the base (1), and the reciprocating screw (8) is connected to a threaded block (801) through a ball nut pair. The top of the outer surface of the threaded block (801) is fixedly connected to a fixed base (2), and the upper cover plate (3) is rotatably embedded inside the fixed base (2). The humidification assembly includes a liquid cylinder (4) fixedly connected to the top of the outer surface of the base (1), and a float plate (401) is slidably embedded inside the liquid cylinder (4). A liquid delivery pipe (6) is provided inside the liquid cylinder (4), and a fixing block (601) is fixedly connected to the outer surface of the liquid delivery pipe (6). A transmission column (605) is rotatably embedded inside the fixing block (601). A double-leaf butterfly valve (7) is located inside the liquid delivery pipe (6), and one side of the outer surface of the transmission column (605) is movably connected to the double-leaf butterfly valve (7).
2. The adsorption-type glass slide separation device for preventing cross-contamination according to claim 1, characterized in that, A limiting rod (802) is fixedly connected to one side of the outer surface of the base (1), and the threaded block (801) is slidably sleeved on the outer surface of the limiting rod (802) in a horizontal direction. Two sets of sliding grooves (201) are provided inside the fixed base (2).
3. The adsorption-type glass slide separation device for preventing cross-contamination according to claim 1, characterized in that, A drive motor (9) is fixedly connected to one side of the outer surface of the base (1), and the output shaft of the drive motor (9) is fixedly connected to the reciprocating lead screw (8).
4. The adsorption-type glass slide separation device for preventing cross-contamination according to claim 1, characterized in that, The air pump (5) is provided with an air outlet pipe (502) inside, and the end of the air outlet pipe (502) away from the air pump (5) is located inside the atomizing nozzle (302).
5. The adsorption-type glass slide separation device for preventing cross-contamination according to claim 4, characterized in that, The top of the outer surface of the float (401) is fixedly connected to a first magnet (402), and the end of the liquid delivery pipe (6) away from the liquid cylinder (4) is located inside the air outlet pipe (502).
6. The adsorption-type glass slide separation device for preventing cross-contamination according to claim 1, characterized in that, A fixing rod (602) is fixedly connected to one side of the outer surface of the fixing block (601), and a fixing frame (603) is fixedly connected to one side of the outer surface of the fixing rod (602).
7. The adsorption-type glass slide separation device for preventing cross-contamination according to claim 6, characterized in that, The fixed frame (603) is rotatably fitted with a rotating gear (604), and the fixed frame (603) is horizontally fitted with a gear plate (606). The outer surface of the rotating gear (604) meshes with the gear plate (606), and one side of the outer surface of the rotating gear (604) is fixedly connected to the transmission column (605).
8. The adsorption-type glass slide separation device for preventing cross-contamination according to claim 7, characterized in that, A second magnet (607) is fixedly connected to one side of the outer surface of the gear plate (606), and a return spring (608) is fixedly connected to one side of the outer surface of the second magnet (607). The end of the return spring (608) away from the second magnet (607) is fixedly connected to the fixing frame (603).