Polygonatum sibiricum tea composition with lipid regulating function and preparation method thereof
By modifying Polygonatum polysaccharide with a gallic acid-L-serine deep eutectic system and synergistically constructing a lipid-regulating complex system with 4-hydroxy-3-methoxyphenylpyruvic acid, the problems of low utilization rate of Polygonatum polysaccharide and single composition of lipid-regulating tea were solved, achieving efficient lipid metabolism regulation and improved safety.
Patent Information
- Application Number
- CN202511683515.0
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-11-17
- Publication Date
- 2026-02-10
AI Technical Summary
Polygonatum polysaccharides have low absorption and utilization rates in the human lipid metabolism system. Existing lipid-regulating teas have single ingredients and lack synergistic mechanisms. Chemical modification methods have problems such as harsh reaction conditions and poor food safety.
Gallic acid-L-serine deep eutectic system was used to modify Polygonatum polysaccharide, which combined with 4-hydroxy-3-methoxyphenylpyruvic acid to form a stable non-covalent complex, enhancing its hydrophobicity and antioxidant stability, and synergistically constructing a lipid-regulating complex system with other natural ingredients.
It significantly improves the bioavailability and lipid-regulating effect of Polygonatum active ingredients, enhances the ability to regulate lipid metabolism, achieves efficient cholesterol efflux and lipid peroxidation inhibition, and ensures the safety and stability of the product.
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Figure CN121489132A_ABST
Abstract
Description
Technical Field
[0001] This invention relates to the field of functional food and natural product chemistry, specifically to a Polygonatum tea composition with lipid-regulating function and its preparation method. Background Technology
[0002] Polygonatum is a traditional Chinese medicine rich in polysaccharides, saponins, flavonoids, and amino acids, possessing the effects of tonifying qi and nourishing yin, strengthening the spleen and moistening the lungs. Modern pharmacological studies have shown that Polygonatum polysaccharides have potential effects on regulating lipid metabolism and improving liver antioxidant capacity. However, the strong hydrophilicity and weak lipid solubility of natural Polygonatum polysaccharides result in low absorption and utilization rates in the human lipid metabolism system, thus limiting their application in functional foods. Existing modification methods mainly employ chemical esterification, carboxymethylation, or acetylation, which suffer from problems such as harsh reaction conditions, activity degradation, and poor food safety.
[0003] Currently, most commercially available lipid-regulating teas rely on conventional ingredients such as green tea, lotus leaf, or hawthorn, resulting in limited efficacy due to their single ingredient composition and lack of structural innovation and synergistic mechanisms. 4-Hydroxy-3-methoxyphenylpyruvic acid is an edible aromatic organic acid derived from vanilla plants, possessing the potential to promote cholesterol excretion and inhibit lipid peroxidation; however, there are no reports of its combined application with active ingredients from Polygonatum sibiricum in lipid-regulating teas.
[0004] Therefore, developing a novel Polygonatum tea composition that utilizes a green deep eutectic system to mildly modify Polygonatum polysaccharides and synergistically constructs them with natural organic small molecules can not only significantly improve the bioavailability and lipid-regulating effect of active ingredients, but also possess good safety and stability, thus having significant research significance and application prospects. Summary of the Invention
[0005] To overcome the technical difficulties mentioned above, such as the poor lipid solubility and low bioavailability of Polygonatum polysaccharides, and the limited synergistic effects of existing lipid-regulating teas, the present invention aims to provide a Polygonatum tea composition with lipid-regulating function and its preparation method. This invention uses a gallic acid-L-serine deep eutectic system to structurally modify Polygonatum extract, enhancing its hydrophobicity and antioxidant stability. Furthermore, it introduces edible organic small molecule 4-hydroxy-3-methoxyphenylpyruvic acid from vanilla plants to synergistically construct a lipid-regulating complex system with the modified Polygonatum extract. This invention significantly improves the lipid metabolism regulation capacity and overall lipid-lowering effect of Polygonatum active ingredients through deep eutectic system modification and synergistic effects with natural small molecules.
[0006] The objective of this invention can be achieved through the following technical solutions:
[0007] A Polygonatum tea composition with lipid-regulating function, the composition comprising the following raw materials in parts by weight: 40-80 parts of modified Polygonatum extract; 5-15 parts of 4-hydroxy-3-methoxyphenylpyruvic acid; 5-10 parts of green tea powder; 5-10 parts of lotus leaf powder; 3-8 parts of malt powder; and 2-5 parts of Luo Han Guo extract; wherein the modified Polygonatum extract is a Polygonatum polysaccharide extract obtained by modification through a gallic acid-L-serine deep eutectic system, and the hydrophobicity and antioxidant stability are improved through esterification and hydrogen bond recombination; and the 4-hydroxy-3-methoxyphenylpyruvic acid is an edible aromatic organic acid derived from vanilla plants, which has the effect of promoting cholesterol excretion and inhibiting lipid peroxidation.
[0008] Optionally, the modified Polygonatum extract comprises the following raw materials in parts by weight: 60-100 parts of Polygonatum extract; 10-20 parts of gallic acid monohydrate; 15-30 parts of L-serine; and 200-300 parts of deionized water.
[0009] Optionally, the preparation method of the modified Polygonatum extract includes the following steps:
[0010] (1) Gallic acid monohydrate and L-serine are mixed and stirred to dissolve them, forming a deep eutectic solution;
[0011] (2) Add the extract of Polygonatum sibiricum to the eutectic solution to carry out the modification reaction;
[0012] (3) After the reaction is completed, the mixture is cooled, dialyzed, and freeze-dried to obtain the modified Polygonatum extract.
[0013] Optionally, the reaction conditions in step (1) are heating to 65-75°C and stirring for 10-30 minutes until completely dissolved.
[0014] Optionally, the reaction conditions for step (2) are to react at 55-65°C for 1-3 hours.
[0015] Optionally, the reaction conditions for step (3) are: cooling to 20-25°C, dialyzing to remove impurities, and freeze-drying at -45 to -55°C.
[0016] Optionally, a method for preparing a Polygonatum odoratum tea composition with lipid-regulating function includes the following steps:
[0017] S1, weigh out modified Polygonatum extract, 4-hydroxy-3-methoxyphenylpyruvic acid, green tea powder, lotus leaf powder, malt powder and monk fruit extract.
[0018] S2, a mixture is prepared by uniformly mixing modified Polygonatum extract, 4-hydroxy-3-methoxyphenylpyruvic acid, green tea powder, lotus leaf powder, malt powder and Luo Han Guo extract;
[0019] S3. The mixture is dried, pulverized, sieved and packaged to obtain the Polygonatum tea composition.
[0020] Optionally, the mixing conditions in step S2 are to stir at 25–35°C for 20–40 minutes until the mixture is homogeneous.
[0021] Optionally, the reaction conditions for step S3 are: drying in a forced-air environment at 45–55°C for 3–5 hours, followed by pulverizing and packaging through a 100–120 mesh sieve.
[0022] The beneficial effects of this invention are:
[0023] This invention utilizes a gallic acid-L-serine deep eutectic system to perform green modification on Polygonatum polysaccharides, resulting in a partially esterified and hydrogen-bonded recombinant structure. This significantly enhances the hydrophobicity and lipid binding capacity of Polygonatum polysaccharides. The modified structure can form a stable non-covalent complex with 4-hydroxy-3-methoxyphenylpyruvic acid molecules, enhancing its synergistic antioxidant and cholesterol efflux activity in lipid oxidation environments, thereby achieving efficient regulation of lipid metabolism. Attached Figure Description
[0024] The invention will now be further described with reference to the accompanying drawings.
[0025] Figure 1 A comparison of the infrared spectra of Polygonatum extract and modified Polygonatum extract;
[0026] Figure 2 A comparison chart showing the reduction rate of total cholesterol in samples with different ratios;
[0027] Figure 3 A comparison chart showing the decrease rate of triglycerides in samples with different ratios;
[0028] Figure 4 A comparison chart of free radical scavenging rates for samples with different formulations;
[0029] Figure 5 This is a comparison chart of lipid adsorption rates for samples with different formulations. Detailed Implementation
[0030] The present invention will be further described below with reference to specific embodiments. However, the present invention is not limited to the following embodiments. Equivalent adjustments made without departing from the spirit and essence of the present invention should also be considered to fall within the protection scope of the present invention.
[0031] Example 1
[0032] The purpose of this embodiment is to verify whether the modified system can maintain the basic lipid-regulating effect and component stability at a lower active ingredient ratio.
[0033] S1, 10 parts of gallic acid monohydrate and 15 parts of L-serine were mixed and heated to 65-70℃ and stirred for 20 minutes to form a deep eutectic solution; 60 parts of Polygonatum extract were added to the deep eutectic solution and reacted at 55-60℃ for 1-2 hours; after the reaction was completed, the mixture was cooled to 20-25℃, purified by dialysis, and freeze-dried at −45-−50℃ to obtain the modified Polygonatum extract;
[0034] S2, weigh 40 parts of modified Polygonatum extract, 5 parts of 4-hydroxy-3-methoxyphenylpyruvic acid, 5 parts of green tea powder, 5 parts of lotus leaf powder, 3 parts of malt powder, and 2 parts of Luo Han Guo extract; stir at 25-30℃ for 20-30 minutes to ensure thorough mixing.
[0035] S3. The mixture is dried in a forced-air dryer at 45-50℃ for 3-4 hours, pulverized and passed through a 100-mesh sieve, and then packaged to obtain a Polygonatum tea composition with lipid-regulating function.
[0036] Example 2
[0037] The purpose of this embodiment is to verify the overall performance of the system in terms of component balance, modification effect, and lipid regulation when the component ratio is at the median.
[0038] S1, 15 parts of gallic acid monohydrate and 20 parts of L-serine were mixed and heated to 70°C and stirred for 25 minutes to form a deep eutectic solution; 80 parts of Polygonatum extract were added and reacted at 60°C for 2 hours; after the reaction, the mixture was cooled to 22°C, purified by dialysis, and then freeze-dried at −50°C to obtain the modified Polygonatum extract. Figure 1 The infrared spectrum comparison shows that the modified Polygonatum extract sample exhibits a distinct new peak at 1730 cm⁻¹, indicating that the gallic acid carboxyl group undergoes an esterification reaction with the hydroxyl group of Polygonatum polysaccharide; a new N–H bending vibration peak appears at 1550 cm⁻¹, indicating that L-serine participates in the formation of amide bond structure; the absorption peak at 3400 cm⁻¹ is wider and stronger, showing an enhanced hydrogen bond network; the intensity of C–O–C and C–O stretching vibration peaks in the 1100–1020 cm⁻¹ range increases, indicating the formation of more ester bonds and hydrogen bonds within the molecule; the overall peak shape is sharper and the absorption intensity is improved, indicating that the modified molecular structure is more ordered and the interaction between hydroxyl, amino and carboxyl groups is significantly enhanced, thus verifying the effectiveness of gallic acid-L-serine deep eutectic modification in improving the structural stability and reactivity of Polygonatum polysaccharide;
[0039] S2, weigh 60 parts of modified Polygonatum extract, 10 parts of 4-hydroxy-3-methoxyphenylpyruvic acid, 8 parts of green tea powder, 8 parts of lotus leaf powder, 5 parts of malt powder, and 3 parts of Luo Han Guo extract; stir at 30℃ for 30 minutes to mix evenly.
[0040] S3. The mixture is dried in a forced-air dryer at 50°C for 4 hours, pulverized and passed through a 100-mesh sieve, and then packaged to obtain a Polygonatum tea composition with lipid-regulating function.
[0041] Example 3
[0042] The purpose of this embodiment is to verify the enhancing effect of the modified system and small molecules on lipid regulation and antioxidant performance when the active ingredient reaches the upper limit.
[0043] S1, 20 parts of gallic acid monohydrate and 30 parts of L-serine were mixed and heated to 70-75℃ and stirred for 30 minutes to form a deep eutectic solution; 100 parts of Polygonatum extract were added and reacted at 60-65℃ for 2-3 hours; after cooling to 20-25℃, impurities were removed by dialyzing and freeze-drying at −50-−55℃ to obtain modified Polygonatum extract;
[0044] S2, weigh 80 parts of modified Polygonatum extract, 15 parts of 4-hydroxy-3-methoxyphenylpyruvic acid, 10 parts of green tea powder, 10 parts of lotus leaf powder, 8 parts of malt powder, and 5 parts of Luo Han Guo extract; stir at 30-35℃ for 30-40 minutes to mix evenly.
[0045] S3. The mixture is dried in a forced-air dryer at 50-55°C for 4-5 hours, pulverized through a 120-mesh sieve, and then packaged to obtain a Polygonatum tea composition with lipid-regulating function.
[0046] Comparative Example 1
[0047] The purpose of this comparative study is to verify the difference in lipid-regulating properties of Polygonatum extract when it is not modified with the gallic acid-L-serine deep eutectic system.
[0048] S1, 80 parts of Polygonatum extract were taken directly without deep eutectic system modification and freeze-dried to obtain unmodified Polygonatum extract;
[0049] S2, weigh out 60 parts of unmodified Polygonatum extract, 10 parts of 4-hydroxy-3-methoxyphenylpyruvic acid, 8 parts of green tea powder, 8 parts of lotus leaf powder, 5 parts of malt powder, and 3 parts of Luo Han Guo extract; stir at 30℃ for 30 minutes to mix evenly.
[0050] S3. The mixture was dried at 50°C for 4 hours by forced air drying, then pulverized and packaged after passing through a 100-mesh sieve to obtain the sample of Comparative Example 1.
[0051] Comparative Example 2
[0052] The purpose of this comparative example is to verify the changes in the modified structure and lipid-regulating effect when the modified system contains only gallic acid and no L-serine.
[0053] S1, dissolve 15 parts of gallic acid monohydrate in deionized water, heat to 70℃ and stir for 25 minutes; add 80 parts of Polygonatum extract, react at 60℃ for 2 hours; cool, dialyze and freeze dry to obtain monogallic acid modified Polygonatum extract.
[0054] S2, weigh 60 parts of the modified Polygonatum extract, 10 parts of 4-hydroxy-3-methoxyphenylpyruvic acid, 8 parts of green tea powder, 8 parts of lotus leaf powder, 5 parts of malt powder, and 3 parts of Luo Han Guo extract; stir at 30°C for 30 minutes to mix evenly.
[0055] S3. The mixture was dried at 50°C for 4 hours by forced air drying, then pulverized and packaged through a 100-mesh sieve to obtain the comparative sample 2.
[0056] Comparative Example 3
[0057] The purpose of this comparative example is to verify the effect of L-serine on the structural modification and lipid-regulating properties of Polygonatum polysaccharide when the modified system contains only L-serine and no gallic acid.
[0058] S1, dissolve 20 parts of L-serine in deionized water, heat to 70℃ and stir for 25 minutes to form a transparent solution; add 80 parts of Polygonatum extract to it, and react at 60℃ for 2 hours; after the reaction is completed, cool to 22℃, remove impurities by dialysis and freeze dry at −50℃ to obtain a single L-serine modified Polygonatum extract.
[0059] S2, weigh 60 parts of the modified Polygonatum extract, 10 parts of 4-hydroxy-3-methoxyphenylpyruvic acid, 8 parts of green tea powder, 8 parts of lotus leaf powder, 5 parts of malt powder, and 3 parts of Luo Han Guo extract; stir at 30°C for 30 minutes to mix evenly.
[0060] S3, the mixture was dried at 50°C for 4 hours by forced air drying, pulverized and passed through a 100-mesh sieve and packaged to obtain the comparative example 3 sample.
[0061] Comparative Example 4
[0062] The purpose of this comparative example is to verify the effect of removing 4-hydroxy-3-methoxyphenylpyruvic acid from the formulation on lipid-regulating activity and antioxidant properties.
[0063] S1, 15 parts of gallic acid monohydrate and 20 parts of L-serine were mixed and heated to 70°C and stirred for 25 minutes to form a deep eutectic solution; 80 parts of Polygonatum extract were added and reacted at 60°C for 2 hours; after the reaction, the mixture was cooled to 22°C, purified by dialysis and freeze-dried at −50°C to obtain the modified Polygonatum extract.
[0064] S2, weigh 60 parts of modified Polygonatum extract, 8 parts of green tea powder, 8 parts of lotus leaf powder, 5 parts of malt powder, and 3 parts of monk fruit extract; stir at 30℃ for 30 minutes to mix evenly;
[0065] S3, the mixture was dried at 50°C for 4 hours by forced air drying, pulverized and passed through a 100-mesh sieve and packaged to obtain the comparative sample 4.
[0066] Performance testing
[0067] 1. Blood lipid regulation performance test
[0068] To evaluate the differences in lipid regulation among the samples, high-fat diet-induced experimental mice were used as models. Samples from Example 2 and Comparative Examples 1 to 4 were administered the tea extract orally. After four weeks of continuous feeding in each group, serum total cholesterol, triglycerides, and high-density lipoprotein (HDL) levels were measured. Results showed that cholesterol and triglyceride levels were significantly reduced in the Example 2 group, while HDL levels were significantly increased; Comparative Examples 1 and 4 showed only slight improvements. This indicates that the synergistic effect of deep eutectic system modification and 4-hydroxy-3-methoxyphenylpyruvic acid is a key factor in enhancing the lipid-regulating effect.
[0069] 2. Antioxidant activity test
[0070] The antioxidant properties of each sample were evaluated using a free radical scavenging assay and a lipid peroxidation inhibition model. Sample 2 showed a high free radical scavenging rate even at low concentrations, and a significantly reduced lipid peroxidation rate. Comparative Examples 2 and 3 exhibited weaker antioxidant capabilities, indicating that the esterification and hydrogen bond network structure formed by the synergistic modification of gallic acid and L-serine significantly improved the antioxidant stability of the polysaccharide system. These results demonstrate that the synergistic structural modification plays a decisive role in enhancing antioxidant performance.
[0071] 3. Lipid adsorption and cholesterol binding capacity test
[0072] The adsorption capacity of each sample for cholesterol and lipids was tested in a simulated gastrointestinal environment. The sample in Example 2 formed a stable emulsion layer at the oil-water interface, exhibiting the highest lipid adsorption rate and significantly enhanced cholesterol binding capacity. The samples in Comparative Examples 1 and 3 showed poor interfacial binding performance and significant oil phase precipitation. The analytical results indicate that the enhanced hydrophobicity and optimized molecular surface polarity of the modified Polygonatum extract facilitated its binding with lipid molecules and the formation of a complex adsorption interface with 4-hydroxy-3-methoxyphenylpyruvic acid, thereby significantly improving lipid adsorption and cholesterol binding capacity.
[0073] 4. Stability and solubility tests
[0074] The stability and solubility of the tea powder were investigated through accelerated storage and thermal dissolution experiments. The sample in Example 2, after being stored at 40°C and high humidity for 30 days, maintained good color, aroma, and solubility, with no obvious stratification or precipitation. Comparative Examples 2 and 4, under the same conditions, exhibited clumping and degradation of active substances. The results indicate that the deep eutectic system modification significantly improved the structural stability of the active components of Polygonatum odoratum and enhanced its dispersing effect with small organic molecules, thereby improving the product's solubility and storage stability.
[0075] Table 1 Comparison of performance test results for each sample
[0076] Sample number Total cholesterol reduction rate (%) Triglyceride reduction rate (%) Free radical scavenging rate (%) Lipid adsorption rate (%) Solubility rating (1-10) Example 1 21.3 19.5 73.6 68.4 8.2 Example 2 28.9 24.7 85.2 79.3 9.5 Example 3 26.4 22.1 80.6 74.5 9.0 Comparative Example 1 12.7 10.4 56.3 51.8 6.1 Comparative Example 2 17.8 15.2 66.5 60.4 7.3 Comparative Example 3 18.4 16.1 67.9 62.7 7.5 Comparative Example 4 15.6 13.9 63.2 58.1 7.0
[0077] As can be seen from the data results in Table 1, Example 2 performed best in all performance indicators, indicating that the synergistic effect between the modified system and the organic small molecules was the most significant. Figure 2 as well as Figure 3 In Example 2, the reduction rates of total cholesterol and triglycerides reached 28.9% and 24.7%, respectively, which were significantly higher than those in Example 1 and Example 3. This indicates that after modification with the gallic acid-L-serine deep eutectic system, the bioavailability and lipid metabolism regulation capacity of Polygonatum polysaccharide were significantly enhanced.
[0078] In terms of antioxidant properties, Figure 4 The free radical scavenging rate of Example 2 reached 85.2%, nearly 30% higher than that of the unmodified sample, demonstrating that the esterification and hydrogen bond network formed during the modification process effectively improved molecular stability and electron donor capability. Although Examples 3 and 1 were slightly lower than Example 2, they were still superior to all comparative examples, demonstrating the overall advantages of synergistic modification of the two components.
[0079] Regarding lipid adsorption rate, Figure 5 Example 2 achieved an adsorption rate of 79.3%, demonstrating excellent lipid binding ability. This indicates that the deep eutectic modification system enhances the hydrophobicity of Polygonatum polysaccharide, making it easier to form a stable adsorption layer at the oil-water interface. Comparative Examples 1 and 4 showed lower adsorption rates of 51.8% and 58.1%, respectively, indicating that effective lipid binding is difficult to achieve without modification or in the absence of small organic molecules.
[0080] Regarding system stability and solubility, Example 2 achieved a solubility score of 9.5, significantly superior to other samples. Its tea powder did not easily clump, separate, or precipitate active substances during storage, indicating that the intermolecular hydrogen bond network formed after modification of the deep eutectic system improved the homogeneous stability of the system. In the comparative samples, although the single-modifier sample showed slight improvement compared to the unmodified sample, it still could not reach the comprehensive performance level of the dual-modified system.
[0081] In summary, the gallic acid-L-serine deep eutectic system modification and the synergistic effect of 4-hydroxy-3-methoxyphenylpyruvic acid used in Example 2 have achieved significant optimization effects in terms of lipid regulation, anti-oxidation, adsorption and system stability, which fully verifies the innovation and efficiency of the design scheme of the present invention.
Claims
1. A Polygonatum tea composition with lipid-regulating function, characterized in that, The composition comprises the following raw materials in parts by weight: 40-80 parts of modified Polygonatum extract; 5-15 parts of 4-hydroxy-3-methoxyphenylpyruvic acid; 5-10 parts of green tea powder; 5-10 parts of lotus leaf powder; 3-8 parts of malt powder; and 2-5 parts of Luo Han Guo extract. The modified Polygonatum extract is a Polygonatum polysaccharide extract modified by a gallic acid-L-serine deep eutectic system, which improves hydrophobicity and antioxidant stability through esterification and hydrogen bond recombination. The 4-hydroxy-3-methoxyphenylpyruvic acid is an edible aromatic organic acid derived from vanilla plants.
2. The Polygonatum tea composition with lipid-regulating function according to claim 1, characterized in that, The modified Polygonatum extract comprises the following raw materials in parts by weight: 60-100 parts Polygonatum extract; 10-20 parts gallic acid monohydrate; 15-30 parts L-serine; and 200-300 parts deionized water.
3. The Polygonatum tea composition with lipid-regulating function according to claim 1, characterized in that, The preparation method of the modified Polygonatum extract includes the following steps: (1) Gallic acid monohydrate and L-serine are mixed and stirred to dissolve and form a deep eutectic solution; (2) Add the extract of Polygonatum sibiricum to the deep eutectic solution to carry out the modification reaction; (3) After the reaction is completed, the mixture is cooled, dialyzed, and freeze-dried to obtain the modified Polygonatum extract.
4. The Polygonatum odoratum tea composition with lipid-regulating function according to claim 3, characterized in that, The reaction conditions for step (1) are to heat to 65-75°C and stir for 10-30 minutes until completely dissolved.
5. The Polygonatum tea composition with lipid-regulating function according to claim 3, characterized in that, The reaction conditions for step (2) are 55-65°C for 1-3 hours.
6. The Polygonatum tea composition with lipid-regulating function according to claim 3, characterized in that, The reaction conditions for step (3) are: cooling to 20-25°C, dialysis to remove impurities, and freeze-drying at -45 to -55°C.
7. A method for preparing a Polygonatum odoratum tea composition with lipid-regulating function, wherein the Polygonatum odoratum tea composition with lipid-regulating function is as described in any one of claims 1 to 6, characterized in that, Includes the following steps: S1, weigh out the modified Polygonatum extract, 4-hydroxy-3-methoxyphenylpyruvic acid, green tea powder, lotus leaf powder, malt powder and monk fruit extract. S2, a mixture is prepared by uniformly mixing modified Polygonatum extract, 4-hydroxy-3-methoxyphenylpyruvic acid, green tea powder, lotus leaf powder, malt powder and Luo Han Guo extract; S3. The mixture is dried, pulverized, sieved and packaged to obtain the Polygonatum tea composition.
8. The method for preparing a Polygonatum odoratum tea composition with lipid-regulating function according to claim 7, characterized in that, The mixing conditions for step S2 are to stir at 25-35°C for 20-40 minutes until the mixture is homogeneous.
9. A method for preparing a Polygonatum odoratum tea composition with lipid-regulating function according to claim 7, characterized in that, The reaction conditions for step S3 are: drying in a forced-air environment at 45-55°C for 3-5 hours, followed by pulverizing and packaging through a 100-120 mesh sieve.