Full-automatic chemiluminescence analyzer

Abstract

The invention discloses a full-automatic chemiluminescence analyzer, and relates to the technical field of medical instruments, the full-automatic chemiluminescence analyzer comprises a frame body structure, the frame body structure is provided with a reagent storage mechanism, a sample introduction structure, a uniform shaking and uncovering structure, a uniform mixing mechanism, a whole blood sample HCT detection structure, a loading structure, a cleaning mechanism, a sample and reagent mechanical arm structure, and a reaction cup mechanical arm structure; whole blood HCT detection and serum sample detection can be automatically realized, a sample introduction structure, a tube clamping mechanism and a uniform shaking and cover opening structure are designed, the working requirements of automatic uniform shaking, cover opening and the like are met, a sample can be directly put on a machine for detection, the sample turnover time is shortened, the automation degree of a full-automatic chemiluminescence analyzer is improved, and the detection efficiency is improved. The kit is suitable for application in emergency clinical laboratory.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of medical devices, in particular to a full-automatic chemiluminescence analyzer. BACKGROUND

[0002] With the vigorous development of medical equipment automation technology, the degree of automation of medical laboratories is also developing rapidly, and more and more manual operations and semi-automatic devices are gradually replaced by laboratory automation devices. Modern medical automatic analysis equipment gradually appears in people's field of vision, which realizes a full-automatic testing system through a transmission track and an analyzer. The full-automatic chemiluminescence analyzer is an automatic device for realizing sample detection through the principle of chemiluminescence.

[0003] In the prior art, most full-automatic chemiluminescence analyzers only detect serum samples and do not have the function of detecting HCT of whole blood samples (such as the existing patent CN201110005816). The instrument structures and processing methods of full-automatic chemiluminescence analyzers of various manufacturers are different to some extent, but the automation degree is not ideal, especially in the processes of sample injection, cap opening, and shaking, and the automation degree is low. Therefore, there is still room for improvement and development. SUMMARY

[0004] The purpose of the present application is to provide a full-automatic chemiluminescence analyzer to solve the above problems mentioned in the background art.

[0005] The present application adopts the following technical solutions:

[0006] The full-automatic chemiluminescence analyzer comprises a frame structure, and the frame structure is provided with a reagent storage mechanism, a sample injection structure, a shaking and cap opening structure, a mixing mechanism, a whole blood sample HCT detection structure, a loading structure, a cleaning mechanism, a sample and reagent mechanical arm structure, and a reaction cup mechanical arm structure.

[0007] When the sample to be detected is serum, the test tube rack containing the serum sample test tube to be detected is placed at position A and enters the instrument through the sample injection structure. Then the sample injection structure moves the test tube to position C to wait for sample suction.

[0008] The sample and reagent mechanical arm structure moves to position Q to take the sample suction head, and the reaction cup mechanical arm structure takes the reaction cup from position G and places it at position D of the mixing mechanism. After the sample and reagent mechanical arm structure takes the sample suction head, it moves to position C to suck liquid from the test tube and spits it into the reaction cup at position D. The mixing mechanism drives the reaction cup to position E. The sample and reagent mechanical arm structure moves to position F to take the reagent and spits it into the reaction cup at position E. After the mixing mechanism mixes the sample and the reagent, it takes the reaction cup through the reaction cup mechanical arm structure and transfers it to position R. The reaction cup is placed in the loading structure for preheating treatment.

[0009] After preheating, the reaction cup robotic arm structure transfers the reaction cup to position H and places it into the cleaning mechanism for cleaning and detection of its luminescence value. Finally, the reaction cup robotic arm structure removes the reaction cup from the cleaning mechanism and transfers it to position N for disposal and then to position K. At the same time, the sample and reagent robotic arm structure transfers the used sample suction head to position J for disposal and then to position K.

[0010] When the sample to be tested is whole blood and needs to be subjected to HCT testing, the test tube rack containing the whole blood sample is placed at position A and enters the instrument through the sample introduction structure. The sample introduction structure includes a tube clamping mechanism that can clamp the test tube. The shake-and-open structure is arranged on the sample introduction structure and performs the mixing and opening action on the test tube. Then the sample introduction structure moves the test tube to position C to wait for sample aspiration. After the sample and reagent robotic arm structure reaches position Q to pick up the sample head, it moves directly to the shake-and-opened test tube to aspirate the sample, and then moves to position M to dispense the sample into the whole blood sample HCT detection structure for testing.

[0011] Preferably, the sample injection structure includes a sample injection frame, on which a sample injection transverse movement device, a sample injection longitudinal movement device, and a tube clamping mechanism are provided; a slidably connected test tube rack loading tray is provided on the sample injection transverse movement device, and a slidably removable test tube rack is placed in the test tube rack loading tray; the sample injection longitudinal movement device is arranged on one side of the sample injection transverse movement device, the tube clamping mechanism is arranged transversely on the sample injection longitudinal movement device, and the shake-to-open cap structure is arranged above the tube clamping mechanism.

[0012] Preferably, the bottom of the test tube rack is provided with a test tube rack groove, and multiple rows of test tube racks are placed side by side on the test tube rack loading tray; the sample injection frame includes a base plate, on which a vertical plate is fixedly installed, and an auxiliary slide rail and a transverse slide rail are provided on the upper part of the vertical plate, with the test tube rack groove and the transverse slide rail slidably connected and engaged; the sample injection transverse movement device includes a transverse movement motor and a transverse movement driven wheel installed on the vertical plate, the transverse movement motor and the transverse movement driven wheel are connected by a transverse movement synchronous belt, a transverse movement belt clamp is fixedly connected to the transverse movement synchronous belt, the transverse movement belt clamp is fixedly connected to the bottom of the transverse movement slide plate, the transverse movement slide plate is fixedly connected to the bottom of the test tube rack loading tray, and the transverse movement slide plate is slidably connected to the auxiliary slide rail by means of a slide groove.

[0013] Preferably, the vertical plate and the horizontal sliding rail are provided with sliding outlets; the sample injection longitudinal movement device includes a sample injection fixing plate and a sample injection channel; clamping mechanisms are provided on both sides of the sample injection channel, the position of the sample injection channel corresponds to the sliding outlet, and the sample injection channel is slidably engaged with the test tube rack; the sample injection fixing plate is located below the sample injection channel, and a longitudinal movement motor and a longitudinal movement driven wheel are provided on the sample injection fixing plate through a longitudinal movement synchronous belt drive; the longitudinal movement fixing plate is fixedly connected to the longitudinal movement synchronous belt, and the longitudinal movement fixing plate is slidably connected to the sample injection fixing plate by means of the slide rail groove; a hook is fixedly connected to the upper part of the longitudinal movement fixing plate, and the hook is slidably arranged at the bottom of the sample injection channel, and the hook is engaged with the groove of the test tube rack.

[0014] Preferably, the tube clamping mechanism includes a tube clamping motor, a tube clamping base plate, and two portal plates; the two portal plates are arranged on both sides of the sample inlet channel, and a tube clamping piece is provided on the top of the portal plates. The bottom of the two portal plates is fixedly connected to two sliding blocks, and the two sliding blocks are slidably connected to the tube clamping base plate; the two sliding blocks are threadedly connected to a bidirectional threaded screw, and one end of the bidirectional threaded screw is poweredly connected to the tube clamping motor.

[0015] Preferably, the shake-to-open structure includes a lifting mechanism, and the lifting mechanism is provided with a swing mechanism;

[0016] The swing mechanism includes a swing frame mounted on a lifting mechanism. One end of the swing frame is equipped with a swing motor, and the other end is equipped with a rotatably connected electric gripper. The output end of the swing motor is fixedly connected to a long threaded rod, and a swing drive block is threaded onto the long threaded rod. The swing drive block is slidably connected to the swing frame via a slide rail and a slide groove. The electric gripper is rotatably connected to the front end of the swing frame via a rotating shaft. After the rotating shaft passes through the swing frame, a first swing rod is fixedly connected to it. The other end of the first swing rod is rotatably connected to one end of a second swing rod, and the other end of the second swing rod is rotatably connected to the swing drive block.

[0017] Preferably, the cleaning mechanism includes a cleaning chamber, a rotating disk, a suction needle, and a discharge needle; a photon counter for detecting the solution in the reaction cup inside the cleaning chamber is also provided on the side wall of the cleaning chamber; an inlet blocking mechanism is provided on the top cover of the cleaning chamber; the suction needle is connected to the suction needle lifting mechanism.

[0018] A rotating disk is arranged inside the cleaning chamber. A rotating drive mechanism is set at the bottom of the cleaning chamber and connected to the rotating disk. A magnetic chuck is set below the rotating disk, and the magnetic chuck has a magnetic suction area. The rotating disk has multiple inverted conical slots arranged in a ring. The inverted conical slots have a structure that is smaller at the top and larger at the bottom. The outer wall of the reaction cup is provided with a retaining edge. The reaction cup is placed in the inverted conical slots and the retaining edge is secured to the rotating disk. A swing drive disk is set below the rotating disk and is poweredly connected to the top support mechanism and the swing drive mechanism.

[0019] Preferably, the suction needle lifting mechanism includes a suction needle frame and a suction needle drive motor. The upper end of the suction needle is mounted on the suction needle frame, and the lower end of the suction needle frame is fixedly connected to the suction needle slide plate. The suction needle slide plate is vertically slidably connected to the side wall of the cleaning chamber via a slide rail groove. The suction needle drive motor is vertically arranged on the bottom plate of the cleaning chamber. A vertical screw is fixedly mounted on the output shaft of the suction needle drive motor. A lifting sleeve is threaded onto the vertical screw, and the lifting sleeve is fixedly connected to the suction needle slide plate.

[0020] Preferably, the oscillating drive disk includes an annular disk with multiple top supports. Each top support has an eccentric groove for supporting a reaction cup, and the top supports correspond to the position of the reaction cup below the dispensing needle. The bottom surface of the annular disk is connected to a top support mechanism, which includes a top support connecting plate. The top end of the top support connecting plate is fixedly connected to the dispensing needle slide plate, and the bottom end of the top support connecting plate is fixedly connected to a lower support frame arranged below the cleaning chamber. A top support shaft is provided on the lower support frame, and the top support shaft is slidably connected to the bottom plate of the cleaning chamber by means of a linear bearing. The top end of the top support shaft passes through the bottom plate of the cleaning chamber and is fixedly connected to the bottom surface of the annular disk.

[0021] Preferably, the rocking drive mechanism includes a top support rotating shaft, the top end of which is fixedly connected to the lower end face of the top support seat, the shaft body of which is rotatably connected to the annular disk, and a rotating pulley fixedly installed at the bottom end of the top support rotating shaft after passing through the annular disk. The rotating pulley is connected to the output end of the rocking drive motor via a synchronous belt, and the rocking drive motor is fixedly connected to the annular disk.

[0022] Compared with the prior art, the beneficial technical effects of the present invention are as follows:

[0023] This invention incorporates an HCT detection structure for whole blood samples and designs a sample injection structure, a tube clamping mechanism, and a shaking and cap opening structure, which meet the needs of automatic shaking and cap opening. Samples can be directly fed into the instrument for testing, shortening sample turnaround time and improving the automation level of the fully automated chemiluminescence analyzer, making it suitable for applications in emergency laboratories. Attached Figure Description

[0024] The present invention will be further described below with reference to the accompanying drawings.

[0025] Figure 0-1 This is a general diagram of a fully automated chemiluminescence analyzer according to the present invention;

[0026] Figure 0-2 Figure 2 shows the overall configuration of a fully automated chemiluminescence analyzer according to the present invention.

[0027] Figure 0-3 This is a general diagram of the operating positions in a fully automated chemiluminescence analyzer according to the present invention;

[0028] Figure 1-1 This is a frame structure diagram of a fully automated chemiluminescence analyzer according to the present invention;

[0029] Figure 1-2 Figure 2 shows the frame structure of a fully automated chemiluminescence analyzer according to the present invention;

[0030] Figure 1-3 Figure 3 shows the frame structure of a fully automated chemiluminescence analyzer according to the present invention;

[0031] Figure 2-1 This is a diagram of the reagent storage mechanism in a fully automated chemiluminescence analyzer according to the present invention;

[0032] Figure 2-2 This is a schematic diagram of the internal structure of the reagent storage mechanism in a fully automated chemiluminescence analyzer according to the present invention;

[0033] Figure 2-3 This is a schematic diagram of the locking system structure in the reagent storage mechanism of a fully automated chemiluminescence analyzer according to the present invention;

[0034] Figure 2-4 This is a schematic diagram of the locking system structure in the reagent storage mechanism of a fully automated chemiluminescence analyzer according to the present invention;

[0035] Figure 2-5 This is a schematic diagram of the reagent bottle structure in a fully automated chemiluminescence analyzer according to the present invention;

[0036] Figure 2-6 This is a cross-sectional view of a reagent bottle in a fully automated chemiluminescence analyzer according to the present invention;

[0037] Figure 2-7 This is a schematic diagram of the internal structure of the reagent storage mechanism in a fully automated chemiluminescence analyzer according to the present invention;

[0038] Figure 3-1 This is a schematic diagram of the sample introduction structure in a fully automated chemiluminescence analyzer according to the present invention;

[0039] Figure 3-2 This is a schematic diagram of a test tube rack structure in a fully automated chemiluminescence analyzer according to the present invention;

[0040] Figure 3-3 This is a schematic diagram of the sample introduction structure in a fully automated chemiluminescence analyzer according to the present invention;

[0041] Figure 3-4 This is a schematic diagram of the sample introduction transverse movement device in the sample introduction structure of a fully automated chemiluminescence analyzer according to the present invention;

[0042] Figure 3-5 This is a schematic diagram of the sample introduction longitudinal movement device in the sample introduction structure of a fully automated chemiluminescence analyzer according to the present invention;

[0043] Figure 3-6 This is a schematic diagram of the sample introduction longitudinal movement device in the sample introduction structure of a fully automated chemiluminescence analyzer according to the present invention;

[0044] Figure 3-7 This is a schematic diagram illustrating the working effect of the hook in the sample introduction structure of a fully automated chemiluminescence analyzer according to the present invention;

[0045] Figure 3-8 This is a schematic diagram of the clamping mechanism in the sample introduction structure of a fully automated chemiluminescence analyzer according to the present invention;

[0046] Figure 4-1 This is a diagram of a shaking and opening structure in a fully automated chemiluminescence analyzer according to the present invention.

[0047] Figure 4-2 Figure 2 shows the shaking and opening structure of a fully automated chemiluminescence analyzer according to the present invention;

[0048] Figure 4-3 Figure 3 shows the shaking and opening structure of a fully automated chemiluminescence analyzer according to the present invention;

[0049] Figure 4-4 Figure 4 shows the shaking and opening structure of a fully automated chemiluminescence analyzer according to the present invention;

[0050] Figure 5-1 Figure 1 shows a mixing mechanism in a fully automated chemiluminescence analyzer according to the present invention;

[0051] Figure 5-2 Figure 2 shows a mixing mechanism in a fully automated chemiluminescence analyzer according to the present invention;

[0052] Figure 6-1 This is a structural diagram of whole blood sample HCT detection in a fully automated chemiluminescence analyzer according to the present invention;

[0053] Figure 6-2 Figure 2 shows the structure of whole blood sample HCT detection in a fully automated chemiluminescence analyzer according to the present invention;

[0054] Figure 7-1 Figure 1 shows the consumable loading structure in a fully automated chemiluminescence analyzer according to the present invention.

[0055] Figure 8-1 Figure 1 shows a reaction cup cleaning mechanism in a fully automated chemiluminescence analyzer according to the present invention;

[0056] Figure 8-2 Figure 2 shows a reaction cup cleaning mechanism in a fully automated chemiluminescence analyzer according to the present invention;

[0057] Figure 8-3 Figure 3 shows a reaction cup cleaning mechanism in a fully automated chemiluminescence analyzer according to the present invention;

[0058] Figure 8-4 Figure 4 shows a reaction cup cleaning mechanism in a fully automated chemiluminescence analyzer according to the present invention;

[0059] Figure 8-5 Figure 5 shows a reaction cup cleaning mechanism in a fully automated chemiluminescence analyzer according to the present invention;

[0060] Figure 8-6 Figure 6 shows a reaction cup cleaning mechanism in a fully automated chemiluminescence analyzer according to the present invention;

[0061] Figure 8-7 Figure 7 shows a reaction cup cleaning mechanism in a fully automated chemiluminescence analyzer according to the present invention;

[0062] Figure 8-8 Figure 8 shows the reaction cup cleaning mechanism in a fully automated chemiluminescence analyzer according to the present invention;

[0063] Figure 8-9 Figure 9 shows a reaction cup cleaning mechanism in a fully automated chemiluminescence analyzer according to the present invention;

[0064] Figure 8-10 Figure 10 shows a reaction cup cleaning mechanism in a fully automated chemiluminescence analyzer according to the present invention;

[0065] Figure 8-11 Figure 11 shows a reaction cup cleaning mechanism in a fully automated chemiluminescence analyzer according to the present invention;

[0066] Figure 9-1 This is a structural diagram of a sample and reagent robotic arm in a fully automated chemiluminescence analyzer according to the present invention;

[0067] Figure 9-2 Figure 2 shows the structure of the sample and reagent robotic arm in a fully automated chemiluminescence analyzer according to the present invention;

[0068] Figure 9-3 Figure 3 shows the structure of the sample and reagent robotic arm in a fully automated chemiluminescence analyzer according to the present invention;

[0069] Figure 9-4 Figure 4 shows the structure of the sample and reagent robotic arm in a fully automated chemiluminescence analyzer according to the present invention;

[0070] Figure 9-5 Figure 5 shows the structure of the sample and reagent robotic arm in a fully automated chemiluminescence analyzer according to the present invention;

[0071] Figure 10-1 This is a structural diagram of the reaction cup robotic arm in a fully automated chemiluminescence analyzer according to the present invention;

[0072] Figure 10-2 Figure 2 shows the structure of the reaction cup robotic arm in a fully automated chemiluminescence analyzer of the present invention;

[0073] Figure 10-3 Figure 3 shows the structure of the reaction cup robotic arm in a fully automated chemiluminescence analyzer of the present invention;

[0074] Explanation of reference numerals in the attached drawings: 001, reaction cup; 001-1, clamp; 002, test tube; 003, pipette tip; 004, test tube rack; 004-1, test tube rack groove;

[0075] Location A: 004 Test tube rack sample loading position; Location B: 002 Test tube scanning and cap opening and whole blood mixing position; Location C: Sample aspiration position; Location D: Sample addition position; Location E: Reagent addition position; Location F: All reagent positions; Location G: 001 Reaction cup placement position; Location H: 001 Reaction cup cleaning and placement position; Location J: 003 Pipette tip disposal position after use; Location K: Waste disposal position; Location M: Whole blood sample HCT detection position; Location N: 001 Reaction cup disposal position after use; Location Q: 003 Pipette tip placement position; Location R: Incubation and heating position;

[0076] Frame Structure 1: 1-1, Control Computer; 1-2, Main Frame; 1-3, Waste Bin;

[0077] Reagent storage mechanism 2: 2-1, Reagent area rack; 2-2, Linear slide rail; 2-3, Refrigeration system; 2-4, Reagent compartment; 2-4.1, Compartment cover; 2-4.2, First gear; 2-4.3, First shaft; 2-5, Reagent bottle; 2-5.1, Reagent bottle gear; 2-5.2, Reagent port one; 2-5.3, Reagent port two; 2-5.4, Reagent port three; 2-5.5, Reagent identification card; 2-5.6, Reagent casing; 2-5.7, First reagent tube; 2-5.8, Second reagent tube; 2-5.9 2-5.10. Third reagent tube; 2-6. Fourth reagent tube; 2-7. Mixing motor for reagent bottle; 2-6.1. Reagent drive wheel; 2-8. Reagent transmission wheel; 2-9. Transmission belt; 2-9. Locking system; 2-9.1. Stepper motor; 2-9.2. Eccentric wheel; 2-9.3. Rocker arm; 2-9.4. Limiting sliding plate; 2-9.5. Guide locking plate; 2-9.6. Stop plate; 2-9.7. Limiting positioning optocoupler; 2-10. Press-to-lock ball; 2-10.1. Locking end; 2-10.2. Fixed end;

[0078] Sample introduction structure 3: 3-1, Sample introduction frame; 3-1.1, Base plate; 3-1.2, Vertical plate; 3-1.3, Auxiliary slide rail; 3-1.4, Horizontal slide rail; 3-1.5, Slide outlet; 3-1.6, Optical coupler shield; 3-1.7, Test tube rack positioning optical coupler; 3-2, Sample introduction horizontal movement device; 3-2.1, Horizontal movement motor; 3-2.2, Horizontal movement motor output wheel; 3-2.3, Horizontal movement driven wheel; 3-2.4, Horizontal movement synchronous belt; 3-2.5, Horizontal movement belt clamp; 3-2.6, Horizontal movement slide plate; 3-3, Sample introduction longitudinal movement device; 3-3.1, Sample introduction fixing plate; 3-3 3-2. Sample inlet channel; 3-3.3. Longitudinal transfer motor; 3-3.4. Longitudinal transfer motor output wheel; 3-3.5. Longitudinal transfer driven wheel; 3-3.6. Longitudinal transfer synchronous belt; 3-3.7. Longitudinal transfer fixing plate; 3-3.8. Hook head; 3-3.9. Code scanner; 3-3.10. Tube detection sensor; 3-4. Tube clamping mechanism; 3-4.1. Tube clamping base plate; 3-4.2. Portal plate; 3-4.3. Tube clamping plate; 3-4.4. Sliding block; 3-4.5. Bidirectional threaded screw; 3-4.6. Tube clamping motor; 3-4.7. Tube clamping positioning optocoupler; 3-5. Test tube rack loading tray;

[0079] Shaking and opening structure 4: 4-1, Lifting mechanism; 4-1.1, C-shaped plate; 4-1.2, Lifting motor; 4-1.3, Lifting screw; 4-1.4, Lifting block; 4-1.5, Lifting slide rail arm; 4-1.6, Slide rail arm positioning optocoupler; 4-2, Swinging mechanism; 4-2.1, Swinging frame; 4-2.2, Swinging motor; 4-2.3, Long threaded rod; 4-2.4, Swinging drive block; 4-2.5, First swing arm; 4-2.6, Second swing arm; 4-2.7, Swinging positioning optocoupler; 4-3, Electric gripper; 4-3.1, Rotating shaft;

[0080] Mixing Mechanism 5: 5-1. Mixing Mechanism Frame; 5-2. Reaction Cup Moving Device; 5-2.1. Fixed Vertical Plate; 5-2.2. Reaction Cup Moving Motor; 5-2.3. Reaction Cup Moving Drive Wheel; 5-2.4. Reaction Cup Moving Driven Wheel; 5-2.5. Reaction Cup Moving Synchronous Belt; 5-2.6. Reaction Cup Moving Plate; 5-3. Reaction Cup Mixing Mechanism; 5-3.1. Reaction Cup Mixing Motor; 5-3.2. Eccentric Shaft; 5-3.3. Swing Plate; 5-3.4. Swing Orientation Slide; 5-3.5. Swing Orientation Rod;

[0081] Whole blood sample HCT detection structure 6: 6-1, HCT rack; 6-2, detection cell; 6-3, light-emitting diode; 6-4, photocell;

[0082] Loading structure 7: 7-1, loader frame; 7-2, storage drawer; 7-3, incubation tank; 7-4, waste outlet one; 7-5, waste outlet two;

[0083] Cleaning Mechanism 8: 8-1. Cleaning Chamber; 8-2. Inlet Covering Mechanism; 8-2.1. Inlet Cover; 8-2.2. Covering Rotary Shaft; 8-2.3. Covering Motor; 8-3. Rotary Disc; 8-4. Inverted Conical Insertion Slot; 8-5. Swing Drive Disc; 8-5.1. Annular Disc; 8-5.2. Top Support; 8-6. Swing Drive Mechanism; 8-6.1. Top Support Rotating Shaft; 8-6.2. Rotating Pulley; 8-6.3. Swing Drive Motor; 8-7. Rotation Drive Mechanism; 8-7.1. Rotation of Rotary Disc Motor; 8-7.2 Rotary disk shaft; 8-8 Suction needle; 8-9 Suction needle lifting mechanism; 8-9.1 Suction needle frame; 8-9.2 Suction needle slide plate; 8-9.3 Suction needle drive motor; 8-9.4 Vertical screw; 8-9.5 Lifting sleeve; 8-10 Dispensing needle; 8-11 Photon counter; 8-12 Top support mechanism; 8-12.1 Top support connecting plate; 8-12.2 Lower support frame; 8-12.3 Top support shaft; 8-13 Magnetic suction area; 8-14 Magnetic suction cup;

[0084] Sample and Reagent Robotic Arm Structure 9: 9-1, Robotic Arm Frame 1; 9-2, X-axis Guide Rail; 9-3, X-axis Rack; 9-4, X-axis Reagent Motor; 9-5, Y-axis Sample Motor; 9-6, Y-axis Sample Rack; 9-7, Y-axis Sample Guide Rail; 9-8, Z-axis Sample Lifting Motor; 9-8.1, Z-axis Sample Screw; 9-9, Z-axis Sample Guide Rail; 9-10, Sample Pipette; 9-10.1, Sample Pipette Threaded Sleeve; 9-11, Y-axis Reagent Motor; 9-12, Y-axis Reagent Rack; 9-13, Y-axis Reagent Guide Rail; 9-14, Z-axis Reagent Lifting Motor; 9-15, Z-axis Synchronous Belt; 9-16, Z-axis Reagent Guide Rail; 9-17, Reagent Needle; 9-18, X-axis Sample Motor;

[0085] The structure of the reaction cup robotic arm is as follows: 10-1, Robotic arm frame 2; 10-2, X-axis reaction cup moving motor; 10-3, X-axis reaction cup moving rack; 10-4, X-axis reaction cup linear guide; 10-5, Y-axis reaction cup motor; 10-6, Y-axis reaction cup rack; 10-7, Y-axis reaction cup linear guide; 10-8, Z-axis reaction cup motor; 10-9, Z-axis reaction cup transmission belt; 10-10, Cup clamping mechanism; 10-10.1, Cup clamping motor; 10-10.2, Cup clamping guide; 10-10.3, Cup clamping cam; 10-10.4, Cup clamping block; 10-10.5, Spring; 10-11, Z-axis plate frame. Detailed Implementation

[0086] To make the technical problems, technical solutions, and beneficial effects of the present invention clearer, the present invention will be further described in detail below with reference to the accompanying drawings and embodiments.

[0087] This embodiment discloses a fully automated chemiluminescence analyzer.

[0088] like Figures 0-1 to 0-3 As shown, the operation method of the fully automated chemiluminescence analyzer and processing method of the present invention is as follows: when the sample to be tested is serum, the test tube 002 containing the serum sample to be tested is placed in the test tube rack 004 and placed at position A, and then enters the instrument through the sample introduction structure 3. The test tube 002 is confirmed at position B, and then the sample introduction structure 3 moves the test tube 002 to position C to wait for sample aspiration. The sample and reagent robotic arm structure 9 moves to position Q to pick up the sample suction head 003. At the same time, the reaction cup robotic arm structure 10 picks up the reaction cup 001 from position G and places the reaction cup 001 into position D of the mixing mechanism 5. After picking up the sample suction head 003, the sample and reagent robotic arm structure 9 moves to position C to aspirate liquid from the test tube 002 and spews the liquid into the reaction cup 001 at position D. The mixing mechanism 5 moves the reaction cup 001 to position E. The sample and reagent robotic arm structure 9 picks up the reagent from position F and spews it into the reaction cup 001 at position E. After the mixing mechanism 5 mixes the sample and reagent, the reaction cup robotic arm structure 10 picks up the reaction cup 001 and transfers it to position R. Position R is equipped with an incubation tank 7-3. The reaction cup robotic arm structure 10 places the reaction cup 001 into the incubation tank 7-3 of the loading structure 7 for preheating treatment. After preheating, the reaction cup robotic arm structure 10 transfers reaction cup 001 to position H and places it into the cleaning mechanism 8 for cleaning and detection of its luminescence value. Finally, the reaction cup robotic arm structure 10 removes reaction cup 001 from the cleaning mechanism 8, transfers it to position N for disposal, and places it into position K. Simultaneously, the sample and reagent robotic arm structure 9 transfers the sample suction head 003 to position J for disposal, and places it into position K. At this point, the entire sample operation process is complete. The concentration of the corresponding detection item in the sample is calculated based on the acquired luminescence value.

[0089] When the sample to be tested is whole blood and needs to be subjected to HCT testing, the test tube rack 004 containing the whole blood sample 002 is placed at position A and enters the instrument through the sample introduction structure 3. The sample introduction structure 3 includes a tube clamping mechanism 3-4, which can clamp the test tube 002. The shake-and-open structure 4 is arranged on the sample introduction structure 3 and can perform the mixing and opening actions on the test tube 002. Then, the sample introduction structure 3 moves the test tube 002 to position C to wait for sample aspiration. After the sample and reagent robotic arm structure 9 moves to position Q to pick up the sampling head 003, it moves directly to the shake-and-opened test tube 002 to aspirate the sample, and then moves to position M to dispense the sample into the whole blood sample HCT detection structure 6 for testing.

[0090] Frame structure 1: such as Figures 1-1 to 1-3As shown, the frame structure 1 includes a main frame 1-2 and a waste bin 1-3; a control computer 1-1 is also installed on the main frame 1-2, which is used to control the operation of the entire system. The waste bin 1-3 is located at position K, which is connected to positions J and N. Positions J and N are waste disposal outlets for the reaction cup 001 and the sampling head 003 after use.

[0091] Reagent storage facility 2:

[0092] like Figures 2-1 to 2-5 As shown, the reagent storage mechanism 2 includes a reagent area rack 2-1, which is slidably connected to the main rack 1-2 via a linear slide rail 2-2, so that the reagent area rack 2-1 can be pulled out from the main rack 1-2 like a drawer.

[0093] A reagent compartment 2-4 is installed on the reagent rack 2-1. The top of the reagent compartment 2-4 is fitted with a compartment cover 2-4.1 via a hinge. Multiple reagent bottles 2-5 are installed inside the reagent compartment 2-4. A refrigeration system 2-3 is installed at the bottom of the reagent compartment 2-4. The refrigeration system 2-3 can refrigerate the reagent compartment 2-4 and refrigerate the reagent bottles 2-5. In this embodiment, the refrigeration system 2-3 is a semiconductor refrigeration chip (Peltier). Semiconductor refrigeration chips are mature existing technology and will not be described here.

[0094] The reagent area rack 2-1 is also equipped with a push-button lock 2-10, which is a push-button type strong magnetic ball lock. It can be locked by pressing and opened by pressing again. It is commonly used in drawers, cabinet doors, etc. (such as the Yalida Beetle cabinet magnetic lock). The push-button lock 2-10 is a common existing technology and will not be described here. The push-button lock 2-10 includes a locking end 2-10.1 and a fixed end 2-10.2. The locking end 2-10.1 is fixedly connected to the reagent area rack 2-1, and the fixed end 2-10.2 is fixedly connected to the whole rack 1-2 by means of the frame. Slide the reagent area rack 2-1 along the linear slide rail 2-2, press the locking end 2-10.1 into the fixed end 2-10.2 to lock the reagent area rack 2-1 with the whole rack 1-2. Push the reagent area rack 2-1 inward again, so that the locking end 2-10.1 presses the fixed end 2-10.2 again, which will separate the reagent area rack 2-1 from the whole rack 1-2.

[0095] like Figures 2-2 to 2-4As shown, since the press-to-open lock 2-10 requires another press to open, to prevent accidental opening due to accidental contact, a locking system 2-9 is also provided at one end of the reagent area frame 2-1 in this embodiment. This system prevents accidental contact of the reagent area frame 2-1 when it is in the locked state, which would cause the fixed end 2-10.2 to be pressed again, thus opening the press-to-open lock 2-10. The locking system 2-9 includes a stepper motor 2-9.1, a guide locking plate 2-9.5, and a stop plate 2-9.6 on the reagent area frame 2-1, all mounted on the frame 1-2. The output end of the stepper motor 2-9.1 is fixedly connected to the center of the eccentric wheel 2-9.2. A rocker arm 2-9.3 is rotatably connected to the eccentric position of the eccentric wheel 2-9.2, and the other end of the rocker arm 2-9.3 is rotatably connected to the limiting sliding plate 2-9.4. The guide locking plate 2-9.5 is fixedly connected to the frame 1-2. The guide locking plate 2-9.5 is provided with a slide rail, and the limiting sliding plate 2-9.4 is provided with a slide groove that cooperates with the slide rail of the guide locking plate 2-9.5. The limiting sliding plate 2-9.4 and the guide locking plate 2-9.5 are slidably connected in the vertical direction. The stepper motor 2-9.1 starts and drives the eccentric wheel 2-9.2 to rotate. With the help of the rocker arm 2-9.3, the limiting sliding plate 2-9.4 moves upward or downward on the guide locking plate 2-9.5. The stop plate 2-9.6 is fixedly connected to the reagent area frame 2-1. When the ball lock 2-10 is pressed and locked, the stop plate 2-9.6 rests against the limiting sliding plate 2-9.4, preventing the reagent area frame 2-1 from being accidentally pressed to the fixed end 2-10.2. When it is necessary to press the fixed end 2-10.2 again to open the ball lock 2-10, the stepper motor 2-9.1 is started, causing the limiting sliding plate 2-9.4 to move downward. At this time, the limiting sliding plate 2-9.4 no longer blocks the stop plate 2-9.6, leaving a gap between the stop plate 2-9.6 and the guide lock plate 2-9.5, allowing the reagent area frame 2-1 to be pushed forward to press the fixed end 2-10.2 again, thereby releasing the ball lock 2-10 and allowing the reagent area frame 2-1 to be opened and pulled out.

[0096] In this embodiment, a positioning optocoupler 2-9.7 is provided below the limiting sliding plate 2-9.4. The positioning optocoupler 2-9.7 is a slot-type optocoupler, mainly composed of a light-emitting diode (LED) and a photosensitive element (such as a photodiode, phototransistor, etc.). An electrical signal is applied to the input terminal to drive the LED to emit light. After the photosensitive element receives the light, it generates a photocurrent, completing the electrical-to-optical-to-electrical conversion process. When the bottom of the limiting sliding plate 2-9.4 falls into the U-shaped slot of the positioning optocoupler 2-9.7, it will block the emitted light signal, thereby achieving the function of identifying the position and finding the zero position. The positioning optocoupler is a prior art and will not be described in detail here.

[0097] like Figures 2-5 to 2-7As shown, reagent bottle 2-5 includes reagent housing 2-5.6, with a reagent identification card 2-5.5 on the top of the reagent housing 2-5.6. A rotatable first reagent tube 2-5.7 is installed inside the reagent housing 2-5.6, containing a reagent containing magnetic beads. The reagent needs to be shaken before use to ensure that the magnetic beads are evenly mixed in the solution for easy aspiration. The magnetic beads have antibodies that react with the antigens in the sample. A reagent bottle gear 2-5.1 is fixedly connected to the bottom of the first reagent tube 2-5.7. A thin film is provided at the mouth of the first reagent tube 2-5.7, with a cross-shaped opening in the middle of the film, allowing direct insertion of the sampling head 003 for sampling. The reagent housing 2-5.6 also contains a second reagent tube 2-5.8, a third reagent tube 2-5.9, and a fourth reagent tube 2-5.10 for placing other reagents. The top of the second reagent tube 2-5.8 is provided with a reagent port 1 2-5.2, the top of the third reagent tube 2-5.9 is provided with a reagent port 2-5.3, and the top of the fourth reagent tube 2-5.10 is provided with a reagent port 3 2-5.4. The structure of reagent port 1 2-5.2, reagent port 2-5.3, and reagent port 3 2-5.4 is the same as the film cap structure of the bottle mouth of the first reagent tube 2-5.7. They are all a layer of silicone film with a cross-shaped opening, which can be directly inserted into the sampling head 003 for sampling.

[0098] like Figure 2-7 The diagram shows the structure after removing the outer shell of reagent compartment 2-4. A rotatable first gear 2-4.2 is located at the bottom of reagent compartment 2-4, meshing with a reagent bottle gear 2-5.1. A first shaft 2-4.3 is fixedly mounted at the bottom of the first gear 2-4.3, rotatably passing through the bottom plate of reagent compartment 2-4 and extending below it, where a reagent drive wheel 2-7 is fixedly connected. A reagent bottle mixing motor 2-6 is mounted on the reagent area frame 2-1. The reagent bottle mixing motor 2-6 has a reagent drive wheel 2-6.1 at its output end. The reagent drive wheel 2-6.1 and the reagent transmission wheel 2-7 are connected by a transmission belt 2-8. When the reagent bottle mixing motor 2-6 rotates, the reagent drive wheel 2-6.1 drives the reagent transmission wheel 2-7 to rotate, which in turn drives the first gear 2-4.2 to rotate. In turn, the reagent bottle gear 2-5.1 drives the first reagent tube 2-5.7 to rotate and mix, so that the magnetic beads are evenly distributed in the liquid so that they can be sucked out.

[0099] Sample introduction structure 3:

[0100] The sample injection structure 3 includes a sample injection frame 3-1, on which a sample injection transverse movement device 3-2, a sample injection longitudinal movement device 3-3, and a tube clamping mechanism 3-4 are provided. The sample injection transverse movement device 3-2 is equipped with a test tube rack loading tray 3-5, in which a removable test tube rack 004 is placed. The sample injection transverse movement device 3-2 can move the test tube rack loading tray 3-5 to the corresponding position of the sample injection longitudinal movement device 3-3. The sample injection longitudinal movement device 3-3 can remove the test tube rack 004 from the test tube rack loading tray 3-5 and transfer it to the tube clamping mechanism 3-4. The tube clamping mechanism 3-4 clamps the test tube 002, thereby allowing the shaking and opening structure 4 to open the cap of the test tube 002.

[0101] like Figures 3-1 to 3-4 As shown, in this embodiment, multiple removable test tubes 002 are placed on the test tube rack 004, and a test tube rack groove 004-1 is provided at the bottom of the test tube rack 004. Multiple rows of test tube racks 004 are placed side by side on the test tube rack loading tray 3-5.

[0102] The sample loading rack 3-1 includes a base plate 3-1.1, a vertical plate 3-1.2 fixedly mounted on the base plate 3-1.1, an auxiliary slide rail 3-1.3 and a transverse slide rail 3-1.4 mounted on the upper part of the vertical plate 3-1.2, and a test tube rack groove 004-1 slidably connected to the transverse slide rail 3-1.4.

[0103] The sample introduction transverse movement device 3-2 includes a transverse movement motor 3-2.1 and a transverse movement driven wheel 3-2.3. The transverse movement motor 3-2.1 is fixedly mounted on the vertical plate 3-1.2. The output end of the transverse movement motor 3-2.1 rotatably passes through the vertical plate 3-1.2 and is connected to the transverse movement motor output wheel 3-2.2. The transverse movement motor output wheel 3-2.2 and the transverse movement driven wheel 3-2.3 are connected by a transverse movement synchronous belt 3-2.4. A transverse movement belt clamp 3-2.5 is fixedly connected to the transverse movement synchronous belt 3-2.4. The transverse movement belt clamp 3-2.5 is fixedly connected to the bottom of the transverse movement slide plate 3-2.6. The transverse movement slide plate 3-2.6 is fixedly connected to the bottom of the test tube rack loading tray 3-5. The side wall of the transverse movement slide plate 3-2.6 is provided with a sliding groove. The transverse movement slide plate 3-2.6 is slidably connected to the auxiliary slide rail 3-1.3 by means of the sliding groove. When the transverse motor 3-2.1 rotates, the output wheel 3-2.2 of the transverse motor drives the transverse synchronous belt 3-2.4 to rotate, which in turn drives the test tube rack loading tray 3-5 to move laterally with the help of the transverse belt clamp 3-2.5 and the transverse sliding plate 3-2.6. At the same time, the transverse sliding plate 3-2.6 and the auxiliary slide rail 3-1.3 provide support and guidance for the test tube rack loading tray 3-5, and the transverse slide rail 3-1.4 and the test tube rack groove 004-1 guide the test tube rack 004.

[0104] like Figure 3-5As shown, in this embodiment, the transverse slide rail 3-1.4 consists of two sections, and a slide outlet 3-1.5 is formed between the two transverse slide rails 3-1.4. The slide outlet 3-1.5 passes through the vertical plate 3-1.2. The slide outlet 3-1.5 cooperates with the sample injection longitudinal movement device 3-3. When the test tube rack 004 moves to the position of the slide outlet 3-1.5, the sample injection longitudinal movement device 3-3 can hook the test tube rack 004 from the test tube rack loading tray 3-5 and move it out.

[0105] In this embodiment, an optical coupler shield 3-1.6 is fixedly connected to the base plate 3-1.1, and a test tube rack positioning optical coupler 3-1.7 is fixedly connected to the bottom of the transverse sliding plate 3-2.6. The test tube rack positioning optical coupler 3-1.7 is a slot-shaped optical coupler. The optical coupler shield 3-1.6 is provided with multiple light-transmitting holes, and the number of light-transmitting holes is consistent with the number of test tube racks 004 that can be held in the test tube rack loading tray 3-5. The optical coupler shield 3-1.6 is arranged on the test tube rack positioning... Within the slotted structure of optocoupler 3-1.7; initially, the optocoupler shield 3-1.6 blocks the light within the test tube rack positioning optocoupler 3-1.7. When the test tube rack positioning optocoupler 3-1.7 moves along with the transverse sliding plate 3-2.6 past the light-transmitting hole, it receives a signal. The spacing of the light-transmitting holes is the same as the spacing of the test tube racks 004 on the test tube rack loading tray 3-5. Furthermore, when the test tube rack positioning optocoupler 3-1.7 encounters... Figure 3-5 When the first light-transmitting hole from the right is shown, the first test tube rack 004 from the left on the test tube rack loading tray 3-5 moves to the sliding outlet 3-1.5 position. At this time, the horizontal movement motor 3-2.1 stops rotating to hook the test tube rack 004 and move it into the sample injection longitudinal movement device 3-3; when the test tube rack positioning optical coupler 3-1.7 encounters... Figure 3-5 When the second light-transmitting hole from the right is shown, the second test tube rack 004 from the left on the test tube rack loading plate 3-5 moves to the slide outlet 3-1.5 position, and so on. This makes it easier to determine the moving position of the test tube rack loading plate 3-5, so as to move different test tube racks 004 on the test tube rack loading plate 3-5 to the slide outlet 3-1.5 position.

[0106] like Figure 3-5 and Figure 3-6 ( Figure 3-6For ease of demonstration, the front part of the sample inlet channel 3-3.2 has been removed, leaving only the rear part. As shown, the sample inlet longitudinal movement device 3-3 includes a sample inlet fixing plate 3-3.1 and a sample inlet channel 3-3.2. A tube clamping mechanism 3-4 is located on both sides of the sample inlet channel 3-3.2, with one end of the sample inlet channel 3-3.2 corresponding to the sliding outlet 3-1.5. The sample inlet channel 3-3.2 consists of two vertically arranged T-shaped frame plates mounted on the frame 1-2. The spacing between the vertical plates of the T-shaped frame plates matches the width of the test tube rack 004. The bottom plates of the T-shaped frame plates support the bottom of the test tube rack 004, and grooves are formed between the bottom plates to facilitate the sliding of the hook head 3-3.8, allowing the test tube rack 004 to move along the sample inlet channel 3-3.2.

[0107] The sample injection fixing plate 3-3.1 is fixedly connected to the frame 1-2 and located below the sample injection channel 3-3.2. A longitudinal movement motor 3-3.3 is provided at one end of the sample injection fixing plate 3-3.1, and a longitudinal movement motor output wheel 3-3.4 is provided at the output end of the longitudinal movement motor 3-3.3. A longitudinal movement driven wheel 3-3.5 is provided at the other end of the sample injection fixing plate 3-3.1. The longitudinal movement motor output wheel 3-3.4 and the longitudinal movement driven wheel 3-3.5 are connected by a longitudinal movement synchronous belt 3-3.6. A longitudinal movement fixing plate 3-3.7 is fixedly connected to the longitudinal movement synchronous belt 3-3.6 by a synchronous belt fixing clamp. A slide rail is provided on the side wall of the sample injection fixing plate 3-3.1, and a sliding groove is provided on the side wall of the longitudinal movement fixing plate 3-3.7. The longitudinal movement fixing plate 3-3.7 is slidably connected to the sample injection fixing plate 3-3.1 by means of the slide rail and sliding groove. A hook head 3-3.8 is fixedly connected to the upper part of the longitudinal moving fixing plate 3-3.7. The hook head 3-3.8 slides along the bottom of the sample inlet channel 3-3.2 (the groove formed by the T-shaped frame plate) under the drive of the longitudinal moving synchronous belt 3-3.6 and the longitudinal moving fixing plate 3-3.7.

[0108] like Figure 3-6 and Figure 3-7 As shown, in the initial state, hook 3-3.8 is located in the slide outlet 3-1.5. When the test tube rack 004 slides to the slide outlet 3-1.5, the transverse motor 3-2.1 stops, and the test tube rack groove 004-1 slides onto hook 3-3.8, so that hook 3-3.8 hooks the test tube rack 004. At this time, the longitudinal motor 3-3.3 starts, and the longitudinal motor output wheel 3-3.4 rotates, driving the longitudinal synchronous belt 3-3.6 and the longitudinal fixed plate 3-3.7 to move. At the same time, hook 3-3.8 hooks the test tube rack groove 004-1 and pulls the test tube rack 004 into the sample inlet channel 3-3.2. When the test tube 002 on the test tube rack 004 is between the tube clamping mechanism 3-4, the longitudinal motor 3-3.3 stops, and the tube clamping mechanism 3-4 can perform the tube clamping action.

[0109] like Figure 3-1As shown in the figure, in this embodiment, a test tube rack positioning optical coupler 3-1.7 is also fixedly connected to the lower end of the longitudinal moving fixing plate 3-3.7. An optical coupler shield 3-1.6 is provided in the groove structure of the test tube rack positioning optical coupler 3-1.7. The optical coupler shield 3-1.6 is fixedly connected to the sample injection fixing plate 3-3.1. The working principle of the test tube rack positioning optical coupler 3-1.7 and optical coupler shield 3-1.6 here is the same as that in the sample feeding transverse movement device 3-2 mentioned above. When the test tube rack positioning optical coupler 3-1.7 moves to the first light-transmitting hole from the left of the optical coupler shield 3-1.6, the first test tube 002 from the right on the test tube rack 004 is located at the corresponding position of the clamping mechanism 3-4. When the test tube rack positioning optical coupler 3-1.7 moves to the second light-transmitting hole from the left of the optical coupler shield 3-1.6, the second test tube 002 from the right on the test tube rack 004 is located at the corresponding position of the clamping mechanism 3-4, and so on. This facilitates the determination of the position of the hook head 3-3.8, so as to move the test tubes 002 at different positions on the test tube rack 004 to the corresponding positions of the clamping mechanism 3-4.

[0110] like Figure 3-3 As shown in the figure, in this embodiment, a barcode scanner 3-3.9 is also provided on the sample inlet channel 3-3.2. When an information code is provided on the test tube rack 004, the barcode scanner 3-3.9 can scan and identify the test tube rack 004.

[0111] In this embodiment, a tube detection sensor 3-3.10 is also provided on the sample injection channel 3-3.2. The tube detection sensor 3-3.10 is a photoelectric sensor. When a test tube 002 on the test tube rack 004 passes by, it will block the light emitted by the photoelectric sensor. Thus, the tube detection sensor 3-3.10 can use the light signal to determine whether a test tube 002 has passed by or to count it.

[0112] like Figure 3-8As shown, the tube clamping mechanism 3-4 includes a tube clamping motor 3-4.6, a tube clamping base plate 3-4.1, and two portal plates 3-4.2. The tube clamping motor 3-4.6 is mounted on the tube clamping base plate 3-4.1, which is mounted on the frame 1-2. The two portal plates 3-4.2 are arranged on both sides of the sample inlet channel 3-3.2. A tube clamping piece 3-4.3 is provided on the top of the portal plate 3-4.2. The two tube clamping pieces 3-4.3 are arranged opposite each other, and the opposite side of the tube clamping pieces 3-4.3 is arc-shaped and equipped with an anti-slip pad. The bottom of the portal plate 3-4.2 is fixedly connected to a sliding block 3-4.4. The bottom surface of the sliding block 3-4.4 is provided with a sliding groove. The tube clamping base plate 3-4.1 is provided with a slide rail, and the sliding block 3-4.4 is slidably connected to the tube clamping base plate 3-4.1. Both sliding blocks 3-4.4 are threadedly connected to the bidirectional threaded screw 3-4.5, and the two sliding blocks 3-4.4 are located on the threads of the bidirectional threaded screw 3-4.5 in opposite directions. A drive wheel is provided at one end of the bidirectional threaded screw 3-4.5, and a drive wheel is also provided at the output end of the clamping motor 3-4.6. The drive wheel at the end of the bidirectional threaded screw 3-4.5 and the drive wheel at the output end of the clamping motor 3-4.6 are connected by a drive belt. When the clamping motor 3-4.6 starts, it drives the bidirectional threaded screw 3-4.5 to rotate. The sliding blocks 3-4.4 move towards each other under the guidance of the slide groove and slide rail, which in turn drives the two portal plates 3-4.2 to move towards each other, and the two clamping plates 3-4.3 to perform a clamping action to hold the test tube 002.

[0113] In this embodiment, a clamping positioning optocoupler 3-4.7 is also provided on the clamping base plate 3-4.1. The clamping positioning optocoupler 3-4.7 is a slot-shaped optocoupler, and a baffle is provided on the sliding block 3-4.4. When the sliding block 3-4.4 moves to the point where the baffle is inserted into the slot-shaped structure of the clamping positioning optocoupler 3-4.7, the clamping positioning optocoupler 3-4.7 can determine that the clamping position is in place.

[0114] Shake well before opening the lid (structure 4):

[0115] like Figure 4-1 and Figure 4-2 As shown, the shaking and opening structure 4 includes a lifting mechanism 4-1, a swing mechanism 4-2 on the lifting mechanism 4-1, and a rotatable electric gripper 4-3 on the swing mechanism 4-2. The electric gripper 4-3 is located above the tube clamping mechanism 3-4, specifically directly above the middle position of the two tube clamping plates 3-4.3. The electric gripper 4-3 is existing technology and will not be described in detail here.

[0116] like Figure 4-3As shown, the lifting mechanism 4-1 includes a C-shaped plate 4-1.1, which is vertically fixed to the frame 1-2. A lifting motor 4-1.2 is installed on the top plate of the C-shaped plate 4-1.1. A rotatable lifting screw 4-1.3 is also installed on the top plate of the C-shaped plate 4-1.1 via bearings. The bottom end of the lifting screw 4-1.3 is rotatably connected to the C-shaped plate 4-1.1 via bearings. The top end of the lifting screw 4-1.3 passes through the top plate of the C-shaped plate 4-1.1 and is fixedly connected to a transmission wheel. A transmission wheel is also fixedly installed at the output end of the lifting motor 4-1.2. The transmission wheel at the output end of the lifting motor 4-1.2 is connected to the transmission wheel of the lifting screw 4-1.3 via a synchronous belt. When the lifting motor 4-1.2 rotates, it can drive the lifting screw 4-1.3 to rotate. A threaded lifting block 4-1.4 is provided on the lifting screw 4-1.3. One end of the lifting block 4-1.4 is fixedly connected to a lifting slide arm 4-1.5. A slide groove is provided on the C-shaped plate 4-1.1. The lifting slide arm 4-1.5 is slidably connected to the slide groove of the C-shaped plate 4-1.1. When the lifting screw 4-1.3 rotates, the threaded lifting block 4-1.4 drives the lifting slide arm 4-1.5 to rise and fall. A swing mechanism 4-2 is provided at the top of the lifting slide arm 4-1.5.

[0117] In this embodiment, a slide rail arm positioning optocoupler 4-1.6 is provided on the C-shaped plate 4-1.1. The slide rail arm positioning optocoupler 4-1.6 is a slot-shaped optocoupler. A blocking plate is provided on the lifting block 4-1.4. When the lifting block 4-1.4 moves to the required position, the blocking plate moves into the slide rail arm positioning optocoupler 4-1.6 to facilitate the positioning of the lifting slide rail arm 4-1.5.

[0118] like Figure 4-4 As shown, the swing mechanism 4-2 includes a swing frame 4-2.1, which is fixedly connected to the top of the lifting slide rail arm 4-1.5. One end of the swing frame 4-2.1 is equipped with a swing motor 4-2.2, and the other end of the swing frame 4-2.1 is equipped with an electric gripper 4-3 that is rotatably connected.

[0119] A long threaded rod 4-2.3 is fixedly connected to the output end of the swing motor 4-2.2. A swing drive block 4-2.4 is threaded onto the long threaded rod 4-2.3. A sliding groove is provided on the bottom end face of the swing drive block 4-2.4. A slide rail is provided on the swing frame 4-2.1. The swing drive block 4-2.4 is slidably connected to the swing frame 4-2.1 by means of the slide rail and the sliding groove. An electric gripper 4-3 is rotatably connected to the front end of the swing frame 4-2.1 by means of a rotating shaft 4-3.1. After the rotating shaft 4-3.1 passes through the swing frame 4-2.1, a first swing rod 4-2.5 is fixedly connected. The other end of the first swing rod 4-2.5 is rotatably connected to one end of a second swing rod 4-2.6. The other end of the second swing rod 4-2.6 is rotatably connected to the swing drive block 4-2.4. When the swing motor 4-2.2 starts, it drives the long threaded rod 4-2.3 to rotate, which in turn drives the swing drive block 4-2.4 to move along the slide rail on the long threaded rod 4-2.3 and the swing frame 4-2.1. At the same time, the swing drive block 4-2.4 pushes the second swing rod 4-2.6 and the first swing rod 4-2.5 to swing. The first swing rod 4-2.5 will drive the electric gripper 4-3 to rotate, which will cause the electric gripper 4-3 to swing back and forth.

[0120] In this embodiment, a swing positioning optocoupler 4-2.7 is provided on the swing frame 4-2.1. The swing positioning optocoupler 4-2.7 is a slot-shaped optocoupler. A blocking plate is provided on the swing drive block 4-2.4. When the blocking plate of the swing drive block 4-2.4 moves into the swing positioning optocoupler 4-2.7, the electric gripper 4-3 is in a vertical position, thereby realizing the position positioning of the electric gripper 4-3 after swinging.

[0121] Since the initial position of the electric gripper 4-3 is directly above the middle position of the two clamping plates 3-4.3, the electric gripper 4-3 is lowered to the position of test tube 002 by the lifting motor 4-1.2, the electric gripper 4-3 is started to clamp the test tube 002, and then the electric gripper 4-3 is raised by the lifting motor 4-1.2 to clamp the test tube 002 from the test tube rack 004 and take it out. The swing motor 4-2.2 is started to shake the test tube 002. After shaking is complete, use the lifting motor 4-1.2 to lower the electric gripper 4-3 again, release the electric gripper 4-3 to put test tube 002 back into test tube rack 004, and at the same time control the motor 4-1.2 to raise the electric gripper 4-3 so that the electric gripper 4-3 is in the position of the stopper of test tube 002. Start the tube clamping motor 3-4.6 and the two tube clamping plates 3-4.3 clamp the test tube 002. Start the electric gripper 4-3 to clamp the stopper. Then use the lifting motor 4-1.2 to raise the electric gripper 4-3 again to remove the stopper.

[0122] Mixing mechanism 5:

[0123] likeFigures 5-1 to 5-2 As shown, the mixing mechanism 5 includes a mixing mechanism frame 5-1 mounted on the main frame 1-2. One end of the mixing mechanism frame 5-1 is the sample addition position D, and the other end is the reagent addition position E. A reaction cup moving device 5-2 is mounted on the mixing mechanism frame 5-1, which can carry the reaction cup 001 between the sample addition position D and the reagent addition position E. The reaction cup moving device 5-2 is also equipped with a reaction cup mixing mechanism 5-3, which can shake and mix the reaction cup 001.

[0124] The reaction cup moving device 5-2 includes a fixed vertical plate 5-2.1 mounted on the mixing mechanism frame 5-1. A reaction cup moving motor 5-2.2 is mounted on one end of the fixed vertical plate 5-2.1. A reaction cup moving drive wheel 5-2.3 is fixedly connected to the output end of the reaction cup moving motor 5-2.2. A rotatable reaction cup moving driven wheel 5-2.4 is mounted on the other end of the fixed vertical plate 5-2.1. The reaction cup moving drive wheel 5-2.3 and the reaction cup moving driven wheel 5-2.4 are connected by a reaction cup moving synchronous belt 5-2.5. A synchronous belt fixing clamp is fixedly connected to the reaction cup moving synchronous belt 5-2.5. The synchronous belt fixing clamp is fixedly connected to the reaction cup moving plate 5-2.6. The reaction cup moving plate 5-2.6 is slidably connected to the fixed vertical plate 5-2.1 by means of a slide rail and slide groove structure. The reaction cup mixing mechanism 5-3 is mounted on the reaction cup moving plate 5-2.6. When the reaction cup moving synchronous belt 5-2.5 rotates, it drives the reaction cup moving plate 5-2.6 to slide along the slide rail on the fixed vertical plate 5-2.1 with the help of the synchronous belt fixing clamp, thereby driving the reaction cup mixing mechanism 5-3 to move.

[0125] The reaction cup mixing mechanism 5-3 includes a reaction cup mixing motor 5-3.1 mounted on a reaction cup moving plate 5-2.6. An eccentric shaft 5-3.2 is mounted at the output end of the reaction cup mixing motor 5-3.1. The lower end of the eccentric shaft 5-3.2 is fixedly connected to the output end of the reaction cup mixing motor 5-3.1. A swing plate 5-3.3 for placing the reaction cup 001 is rotatably connected to the upper end of the eccentric shaft 5-3.2 at an eccentric position via a bearing. A swing directional groove 5-3.4 is mounted on the swing plate 5-3.3. A swing directional rod 5-3.5 is fixedly mounted on the reaction cup moving plate 5-2.6. The upper end of the swing directional rod 5-3.5 is located within the swing directional groove 5-3.4. When the reaction cup mixing motor 5-3.1 is started, the eccentric shaft 5-3.2 drives the swing plate 5-3.3 and the swing directional groove 5-3.4 to swing and sway under the action of the swing directional rod 5-3.5.

[0126] In this embodiment, a slotted positioning optical coupler is provided on the mixing mechanism frame 5-1, and a shielding plate is provided at the bottom of the reaction cup moving plate 5-2.6. The shielding plate has a light-transmitting hole. The slotted positioning optical coupler on the mixing mechanism frame 5-1 cooperates with the shielding plate at the bottom of the reaction cup moving plate 5-2.6 to facilitate the detection and positioning of the moving position of the reaction cup moving plate 5-2.6.

[0127] In this embodiment, a shielding plate is provided on the eccentric shaft 5-3.2, and the shielding plate is provided with a light-transmitting hole. A slotted positioning optical coupler is provided on the upper end of the reaction cup moving plate 5-2.6. The slotted positioning optical coupler cooperates with the shielding plate of the eccentric shaft 5-3.2 to facilitate positioning and zeroing of the rotation angle of the eccentric shaft 5-3.2.

[0128] Structure 6 of whole blood sample HCT detection:

[0129] like Figure 6-1 and Figure 6-2 As shown, the whole blood sample HCT detection structure includes an HCT frame 6-1 mounted on a main frame 1-2. The HCT frame 6-1 has a detection cell 6-2 for holding the sample to be tested. The detection cell 6-2 is made of transparent material. A light-emitting diode (LED) 6-3 is located on one side of the detection cell 6-2, and a photodiode 6-4 is located on the opposite side. The photodiode 6-4 is connected to an external detection system. The light signal emitted by the LED 6-3 passes through the sample in the detection cell 6-2 and is received by the photodiode 6-4. The external detection system analyzes the received light signal to detect the sample. This whole blood sample HCT detection structure is existing technology and will not be described in detail here.

[0130] Loading structure 7:

[0131] like Figure 7-1 As shown, the loading structure 7 includes a loading frame 7-1, on which a reaction cup holder and a pipette head holder are provided for placing reaction cup 001 and pipette head 003. The loading frame 7-1 also includes an incubation tank 7-3, which is equipped with an electric heating wire for heating. The loading frame 7-1 also has two waste inlets, 7-4 and 7-5, for disposing of discarded reaction cup 001 and pipette head 003. At the bottom of the loading frame 7-1, there is a storage drawer 7-2 for storing consumables and other items. Like the reagent area frame 2-1, the storage drawer 7-2 is removable and mounted on the main frame 1-2. Similarly, the storage drawer 7-2 is equipped with a press-button lock 2-10 and a locking system 2-9 to secure it to the main frame 1-2.

[0132] Cleaning unit 8:

[0133] In this embodiment, the reaction cup 001 contains a mixture of the sample to be tested, magnetic bead reagent, and acridine ester (and other reagents). The antigen or antibody coated on the magnetic beads can bind to the antibody or antigen of the sample (i.e., specific binding), and at the same time, the acridine ester can also bind to the antibody or antigen of this part of the sample, so that the acridine ester is adsorbed on the magnetic beads (if the antigen of the sample is being detected, the magnetic beads are coated with antibodies; if the antibody of the sample is being detected, the magnetic beads are coated with antigens). Since the number of magnetic beads is fixed, the number of antigens or antibodies coated on the magnetic beads is also fixed, and the number of sample antibodies or antigens that can be adsorbed and reacted is also fixed. It is necessary to wash away the excess unbound sample and reagents (this process requires first using the external magnetic attraction area 8-13 to fix the magnetic beads, then removing the excess sample and reagent solution inside, adding washing solution, then using the external magnetic attraction area 8-13 to fix the magnetic beads again and removing the excess solution, repeating this washing process three times), leaving only the magnetic beads. Then, excitation solution is added. After the excitation solution is added, the acridine ester adsorbed and fixed on the magnetic beads will produce a luminescent reaction. Then, the reaction cup 001 is moved to the photon counter 8-11 position for optical detection.

[0134] like Figures 8-1 to 8-8 As shown, the cleaning mechanism 8 includes a cleaning chamber 8-1. The top cover of the cleaning chamber 8-1 is provided with an inlet for placing the reaction cup 001. The top cover of the cleaning chamber 8-1 is provided with an inlet blocking mechanism 8-2. The inlet blocking mechanism 8-2 can open or close the inlet to ensure that the cleaning chamber 8-1 is sealed and not exposed to light.

[0135] The rotating disk 8-3 is connected to the rotating drive mechanism 8-7 located at the bottom of the cleaning chamber 8-1, and is driven by the rotating drive mechanism 8-7 to rotate the rotating disk 8-3. A magnetic chuck 8-14 is located below the rotating disk 8-3 and is fixedly mounted on the bottom plate of the cleaning chamber 8-1. The magnetic chuck 8-14 is provided with a magnetic suction area 8-13 corresponding to the position of the reaction cup 001 (it should be noted that the magnetic suction area 8-13 is not provided at the liquid discharge position of the liquid discharge needle 8-10, but is provided at the liquid suction position and other positions). When the reaction cup 001 on the rotating disk 8-3 is rotated to the position corresponding to the magnetic suction area 8-13, the magnetic suction area 8-13 is provided with a magnet, and the magnetic suction area 8-13 attracts the magnetic beads in the reaction cup 001. After the magnetic beads are attracted to the side wall of the reaction cup 001, the liquid suction action is performed.

[0136] like Figure 8-3As shown, in this embodiment, the rotary drive mechanism 8-7 includes a rotary disk motor 8-7.1 and a vertically arranged rotary disk shaft 8-7.2. The rotary disk motor 8-7.1 is located below the cleaning chamber 8-1. The rotary disk shaft 8-7.2 rotatably passes through the magnetic chuck 8-14. The upper end of the rotary disk shaft 8-7.2 is fixedly connected to the bottom surface of the rotary disk 8-3. The lower part of the rotary disk shaft 8-7.2 is rotatably connected to the bottom plate of the cleaning chamber 8-1 via a bearing. The bottom end of the rotary disk shaft 8-7.2 passes through the bottom plate of the cleaning chamber 8-1 and is connected to the rotary disk motor 8-7.1 via a synchronous belt and synchronous pulley. When the rotary disk motor 8-7.1 is started, it can drive the rotary disk shaft 8-7.2 and the rotary disk 8-3 to rotate. After the reaction cup 001 is placed in the rotary disk 8-3, it can be moved to the magnetic suction, liquid suction, liquid discharge, photon counting, and other operation positions by rotation.

[0137] like Figure 8-1 , Figure 8-2 , Figure 8-7 and Figure 8-8 As shown, the cleaning chamber 8-1 is equipped with four suction needles 8-8 and four discharge needles 8-10 that are inserted into the reaction cup 001. The suction needles 8-8 are connected to a suction needle lifting mechanism 8-9, which can lower the suction needles 8-8 into the reaction cup 001 to draw liquid, or raise them to remove them from the reaction cup 001. The discharge needles 8-10 are connected to an external liquid dispensing system, allowing them to dispense liquid into the reaction cup 001. A sleeve is installed on the top cover of the cleaning chamber 8-1, corresponding to the position of the reaction cup 001 on the rotating disk 8-3. The needles of the suction needles 8-8 and discharge needles 8-10 are slidably arranged inside the sleeve, ensuring that the liquid drawing and dispensing processes do not cause light leakage into the interior of the cleaning chamber 8-1.

[0138] like Figure 8-2 , Figure 8-3 and Figure 8-5 As shown, the cleaning chamber 8-1 has a rotating disk 8-3 inside. The rotating disk 8-3 has multiple inverted conical slots 8-4 arranged in a ring. The inverted conical slots 8-4 have a structure that is smaller at the top and larger at the bottom. The outer wall of the reaction cup 001 has a retaining edge 001-1. When the reaction cup 001 is placed in the inverted conical slot 8-4, the retaining edge 001-1 is secured to the rotating disk 8-3, preventing the reaction cup 001 from falling off. The conical area of ​​the inverted conical slot 8-4 also provides space for the reaction cup 001 to swing. After the reaction cup 001 is placed in the inverted conical slot 8-4, the reaction cup 001 is located on the outer side of the peripheral wall of the magnetic suction cup 8-14, and the reaction cup 001 is positioned to mate with the magnetic suction area 8-13. In this embodiment, the cleaning chamber 8-1 has a cylindrical structure.

[0139] Below the rotating disk 8-3 is a swing drive disk 8-5, which is powered by the top support mechanism 8-12 and the swing drive mechanism 8-6. The top support mechanism 8-12 can lift the reaction cup 001, and the swing drive mechanism 8-6 can rotate the reaction cup 001 to make it swing and mix.

[0140] like Figure 8-6 As shown, in this embodiment, the inlet blocking mechanism 8-2 includes an inlet cover 8-2.1 and a blocking motor 8-2.3. The inlet cover 8-2.1 has a Z-shaped plate structure. One end of the inlet cover 8-2.1 blocks the inlet of the cleaning chamber 8-1, and the other end of the inlet cover 8-2.1 is connected to a blocking rotating shaft 8-2.2. The blocking rotating shaft 8-2.2 is rotatably mounted on the top cover of the cleaning chamber 8-1 by means of a frame. One end of the blocking rotating shaft 8-2.2 is connected to the output end of the blocking motor 8-2.3 by means of a synchronous belt and synchronous pulley. When the shielding motor 8-2.3 starts, it drives the shielding shaft 8-2.2 to rotate, causing the inlet cover 8-2.1 to rotate upward and open the inlet of the cleaning chamber 8-1, allowing the reaction cup 001 to be placed in. When the shielding motor 8-2.3 rotates in the opposite direction, the shielding shaft 8-2.2 drives the inlet cover 8-2.1 to rotate downward, thus covering the inlet of the cleaning chamber 8-1 again.

[0141] like Figure 8-7 As shown, in this embodiment, the aspiration needle 8-8 is arranged vertically within the sleeve. The aspiration needle lifting mechanism 8-9 includes an aspiration needle frame 8-9.1 and an aspiration needle drive motor 8-9.3. The upper end of the aspiration needle 8-8 is fixedly mounted on the aspiration needle frame 8-9.1, and the lower end of the aspiration needle frame 8-9.1 is fixedly connected to the aspiration needle slide plate 8-9.2. A vertically arranged slide rail is provided on the side wall of the cleaning chamber 8-1, and a slide groove is provided on the aspiration needle slide plate 8-9.2. The aspiration needle slide plate 8-9.2 can slide vertically on the side wall of the cleaning chamber 8-1 with the help of the slide rail and slide groove. A suction needle drive motor 8-9.3 is vertically arranged on the bottom plate of the cleaning chamber 8-1. A vertical screw 8-9.4 is fixedly installed on the output shaft of the suction needle drive motor 8-9.3. A lifting sleeve 8-9.5 is threadedly connected to the vertical screw 8-9.4, and the lifting sleeve 8-9.5 is fixedly connected to the suction needle slide plate 8-9.2. When the suction needle drive motor 8-9.3 starts, it drives the vertical screw 8-9.4 to rotate. The lifting sleeve 8-9.5 is fixedly connected to the suction needle slide plate 8-9.2. Under the guidance of the slide rail on the side wall of the cleaning chamber 8-1, the suction needle holder 8-9.1 can move up and down, so that the suction needle 8-8 can be inserted downward into the reaction cup 001 for liquid aspiration.

[0142] like Figures 8-8 to 8-10As shown, the swing drive disk 8-5 includes an annular disk 8-5.1, on which multiple top supports 8-5.2 are provided. Each top support 8-5.2 has an eccentrically positioned groove for supporting the reaction cup 001, and the groove of the top support 8-5.2 corresponds to the position of the reaction cup 001 below the dispensing needle 8-10. The bottom surface of the annular disk 8-5.1 is connected to a top support mechanism 8-12, which pushes the reaction cup 001 upwards towards the dispensing needle 8-10 for dispensing. The top support mechanism 8-12 includes a top support connecting plate 8-12.1. The top end of the top support connecting plate 8-12.1 is fixedly connected to the suction needle slide plate 8-9.2, and the bottom end of the top support connecting plate 8-12.1 is fixedly connected to the lower support frame 8-12.2 located below the cleaning chamber 8-1. The lower support frame 8-12.2 is equipped with a top support shaft 8-12.3, which is slidably connected to the bottom plate of the cleaning chamber 8-1 via a linear bearing. The top of the .3 needle passes through the bottom plate of the cleaning chamber 8-1 and is fixedly connected to the bottom surface of the annular disc 8-5.1. When the suction needle slide plate 8-9.2 moves upward, it will push the top support seat 8-5.2 upward with the help of the top support connecting plate 8-12.1, the lower support bracket 8-12.2, and the top support shaft 8-12.3, thus contacting the bottom of the reaction cup 001 and lifting the reaction cup 001 upward a certain distance, so that the mouth of the reaction cup 001 is close to the discharge needle 8-10 for discharge. After the discharge needle 8-10 has finished discharging, the suction needle slide plate 8-9.2 moves downward, causing the reaction cup 001 to move away from the discharge needle 8-10. Figure 8-9 The image shows the rising state during effusion.

[0143] The swing drive mechanism 8-6 includes a top support rotating shaft 8-6.1. The top end of the top support rotating shaft 8-6.1 is fixedly connected to the lower end face of the top support seat 8-5.2. The shaft body of the top support rotating shaft 8-6.1 is rotatably connected to the annular disk 8-5.1. The bottom end of the top support rotating shaft 8-6.1 passes through the annular disk 8-5.1 and is fixedly mounted with a rotating pulley 8-6.2. The rotating pulley 8-6.2 is connected to the output end of the swing drive motor 8-6.3 through a synchronous belt. The swing drive motor 8-6.3 is fixedly connected to the annular disk 8-5.1. When the top support 8-5.2 supports the reaction cup 001 upwards and the retaining edge 001-1 leaves the rotating disk 8-3, the swing drive motor 8-6.3 starts, driving the rotating pulley 8-6.2 to rotate, causing the top support rotating shaft 8-6.1 to also rotate. The rotation center line of the top support rotating shaft 8-6.1 does not coincide with the center of the groove of the top support 8-5.2. Since the upper end of the reaction cup 001 is limited to the upper opening of the inverted conical retaining port 8-4, the lower space of the inverted conical retaining port 8-4 provides space for the reaction cup 001 to rotate and swing, so that the reaction cup 001 can perform a conical swinging and shaking action under the action of the top support 8-5.2.

[0144] likeFigure 8-11 As shown, a photon counter 8-11 is also provided on the side wall of the cleaning chamber 8-1. The photon counter 8-11 can detect the solution in the reaction cup 001 inside the cleaning chamber 8-1. In simple terms, the photon counter 8-11 includes a counter frame 8-11.1, a light inlet channel 8-11.2 on the counter frame 8-11.1, and a counter body 8-11.3 on the other side of the counter frame 8-11.1 opposite to the light inlet channel 8-11.2. The counter frame 8-11.1 has a light-transmitting hole. The positions of the lens of the counter body 8-11.3, the light-transmitting hole on the counter frame 8-11.1, and the light inlet channel 8-11.2 correspond to each other. The position of the light inlet channel 8-11.2 corresponds to the reaction cup 001 to be detected. The light emitted by the magnetic bead inside the reaction cup 001 can be received by the lens of the counter body 8-11.3 through the light inlet channel 8-11.2. An opening is provided on the side wall of the light inlet channel 8-11.2. A shutter motor 8-11.4 is also provided on the counter frame 8-11.1. The output end of the shutter motor 8-11.4 is rotatably mounted on the counter frame 8-11.1 via a bearing, and the output end of the shutter motor 8-11.4 is located directly above the light inlet channel 8-11.2. A shutter shutter baffle 8-11.5 is fixedly connected to the output end of the shutter motor 8-11.4. In the initial position, the shutter baffle 8-11.5 is located inside the light inlet channel 8-11.2, blocking the lens of the counter body 8-11.3. When the shutter motor 8-11.4 is started, it drives the shutter baffle 8-11.5 to rotate, and the shutter baffle 8-11.5 rotates out from the opening on the light inlet channel 8-11.2, so the lens of the counter body 8-11.3 is no longer blocked and can perform detection work.

[0145] The detection principle of the photon counter 8-11, as an existing technology, will not be described in detail here.

[0146] Sample and reagent robotic arm structure 9:

[0147] like Figures 9-1 to 9-5 As shown, the sample and reagent robotic arm structure 9 includes a robotic arm frame 9-1, a sample pipette 9-10, a Y-axis sample guide rail 9-7, a Y-axis reagent guide rail 9-13, and a reagent needle 9-17.

[0148] The robotic arm frame 9-1 has X-axis guide rails 9-2 and X-axis racks 9-3 on both sides. The Y-axis sample guide rail 9-7 has grooves at both ends. The X-axis guide rail 9-2 is slidably connected to the two ends of the Y-axis sample guide rail 9-7 via these grooves. An X-axis sample motor 9-18 is located at the end of the Y-axis sample guide rail 9-7. A gear is installed at the output end of the X-axis sample motor 9-18, and this gear meshes with the X-axis rack 9-3. When the X-axis sample motor 9-18 starts, the gear connection allows the Y-axis sample guide rail 9-7 to slide on the X-axis guide rail 9-2.

[0149] like Figure 9-2 As shown, the Z-axis sample guide rail 9-9 is slidably connected to the Y-axis sample guide rail 9-7 via the frame and the slide rail groove. The Z-axis sample guide rail 9-9 is equipped with a Y-axis sample motor 9-5, and the output end of the Y-axis sample motor 9-5 is equipped with a gear. The Y-axis sample guide rail 9-7 is also equipped with a Y-axis sample rack 9-6. The output end gear of the Y-axis sample motor 9-5 meshes with the Y-axis sample rack 9-6. When the Y-axis sample motor 9-5 is started, it can drive the Z-axis sample guide rail 9-9 to slide along the Y-axis sample guide rail 9-7.

[0150] The sample pipette 9-10 is equipped with a sliding groove, which allows it to slide against the Z-axis sample guide rail 9-9. A Z-axis sample lifting motor 9-8 is mounted on the top of the Z-axis sample guide rail 9-9, and a Z-axis sample screw 9-8.1 is mounted at the output end of the motor. The bottom end of the screw 9-8.1 is rotatably connected to the bottom of the Z-axis sample guide rail 9-9. A sample pipetting threaded sleeve 9-10.1 is fixedly connected to the back of the pipette 9-10, and is threaded onto the Z-axis sample screw 9-8.1. When the Z-axis sample lifting motor 9-8 is started, the rotation of the Z-axis sample screw 9-8.1 drives the sample pipette 9-10 to move up and down.

[0151] like Figure 9-5 As shown, the Y-axis reagent guide rail 9-13 has sliding grooves at both ends. The X-axis guide rail 9-2 is slidably connected to the two ends of the Y-axis reagent guide rail 9-13 through the sliding grooves. The end of the Y-axis reagent guide rail 9-13 is equipped with an X-axis reagent motor 9-4. The output end of the X-axis reagent motor 9-4 is equipped with a gear. The output gear of the X-axis reagent motor 9-4 meshes with the X-axis rack 9-3. When the X-axis reagent motor 9-4 starts, the gear connection allows the Y-axis reagent guide rail 9-13 to slide on the X-axis guide rail 9-2.

[0152] Z-axis reagent guide rail 9-16 is slidably connected to Y-axis reagent guide rail 9-13 via a slide rail groove through the frame. Y-axis reagent motor 9-11 is installed on Z-axis reagent guide rail 9-16. Gear is installed at the output end of Y-axis reagent motor 9-11. Y-axis reagent rack 9-12 is also installed on Y-axis reagent guide rail 9-13. The gear at the output end of Y-axis reagent motor 9-11 meshes with Y-axis reagent rack 9-12. When Y-axis reagent motor 9-11 is started, it can drive Z-axis reagent guide rail 9-16 to slide along Y-axis reagent guide rail 9-13.

[0153] Reagent needle 9-17 is mounted on a frame with a sliding groove. Reagent needle 9-17 is slidably connected to Z-axis reagent guide rail 9-16 via this groove. A Z-axis reagent lifting motor 9-14 is located at the top of the frame containing Z-axis reagent guide rail 9-16. A synchronous pulley is located at the output end of the Z-axis reagent lifting motor 9-14, and a driven pulley is located at the bottom of the frame. This driven pulley is connected to the synchronous pulley of the Z-axis reagent lifting motor 9-14 via a Z-axis synchronous belt 9-15. A synchronous belt clamp is fixedly connected to the Z-axis synchronous belt 9-15 and is fixedly connected to the reagent needle 9-17 frame. When the Z-axis reagent lifting motor 9-14 is started, the Z-axis synchronous belt 9-15 rotates, thereby driving the synchronous belt clamp and the reagent needle 9-17 frame to move up and down.

[0154] Reaction cup robotic arm structure 10:

[0155] like Figures 10-1 to 10-3 As shown, the reaction cup robotic arm structure 10 includes a robotic arm frame 10-1. An X-axis reaction cup linear guide rail 10-4 and an X-axis reaction cup moving rack 10-3 are provided on the robotic arm frame 10-1. An X-axis reaction cup moving motor 10-2 is slidably connected to the X-axis reaction cup linear guide rail 10-4 through a slide rail groove. A gear is provided at the output end of the X-axis reaction cup moving motor 10-2 and meshes with the X-axis reaction cup moving rack 10-3. When the X-axis reaction cup moving motor 10-2 is started, it is driven to move along the X-axis reaction cup linear guide rail 10-4 by means of the gear and rack. The Y-axis reaction cup linear guide 10-7 is fixedly mounted on the frame. The X-axis reaction cup moving motor 10-2 is fixedly connected to the frame on which the Y-axis reaction cup linear guide 10-7 is located. A Y-axis reaction cup rack 10-6 is provided on one side of the frame on which the Y-axis reaction cup linear guide 10-7 is located. The Y-axis reaction cup linear guide 10-7 and the Y-axis reaction cup motor 10-5 are slidably connected through the frame. The output end of the Y-axis reaction cup motor 10-5 is provided with a gear that meshes with the Y-axis reaction cup rack 10-6. When the Y-axis reaction cup motor 10-5 is started, it can drive the Y-axis reaction cup motor 10-5 to move on the Y-axis reaction cup linear guide 10-7 and the Y-axis reaction cup rack 10-6.

[0156] The Y-axis reaction cup motor 10-5 is fixedly connected to the Z-axis plate frame 10-11. The Z-axis plate frame 10-11 is slidably connected to the Y-axis reaction cup linear guide rail 10-7. The Z-axis reaction cup motor 10-8 is set at the bottom of the Z-axis plate frame 10-11. A synchronous pulley is set at the output end of the Z-axis reaction cup motor 10-8. A driven pulley is set at the top of the Z-axis plate frame 10-11. The synchronous pulley and the driven pulley at the output end of the Z-axis reaction cup motor 10-8 are connected by transmission through the Z-axis reaction cup transmission belt 10-9. A cup clamping mechanism 10-10 is fixedly connected to the Z-axis reaction cup transmission belt 10-9 for clamping the reaction cup 001.

[0157] The cup clamping mechanism 10-10 includes a cup clamping motor 10-10.1, a cup clamping guide rail 10-10.2, and a cup clamping cam 10-10.3, all mounted on the Z-axis plate frame 10-11. The middle position of the cup clamping cam 10-10.3 is fixedly connected to the output end of the cup clamping motor 10-10.1. The cup clamping guide rail 10-10.2 is provided with two cup clamping blocks 10-10.4 that are slidably connected by a sliding groove. The backs of the two cup clamping blocks 10-10.4 are connected together by a spring 10-10.5. The two opposing sidewalls of the two cup clamping blocks 10-10.4 abut against the outer peripheral wall of the cup clamping cam 10-10.3. When the cup clamping motor 10-10.1 starts, the cup clamping cam 10-10.3 rotates and then pushes outward to make the two cup clamping blocks 10-10.4 move to both sides to open. Then the entire cup clamping mechanism 10-10 moves downward so that the two cup clamping blocks 10-10.4 are placed on both sides of the reaction cup 001. Then the cup clamping motor 10-10.1 is controlled to reverse, and the two cup clamping blocks 10-10.4 move towards the middle under the tension of the spring 10-10.5 to clamp the reaction cup 001.

[0158] The embodiments described above are merely preferred embodiments of the present invention and are not intended to limit the scope of the present invention. Various modifications and improvements made by those skilled in the art to the technical solutions of the present invention without departing from the spirit of the present invention should fall within the protection scope defined by the claims of the present invention.

Claims

1. A fully automated chemiluminescence analyzer, characterized in that: Includes a frame structure (1), on which are provided a reagent storage mechanism (2), a sample injection structure (3), a shaking and opening structure (4), a mixing mechanism (5), a whole blood sample HCT detection structure (6), a loading structure (7), a cleaning mechanism (8), a sample and reagent robotic arm structure (9), and a reaction cup robotic arm structure (10); When the sample to be tested is serum, the test tube rack (004) containing the test tube (002) of the serum sample to be tested is placed at position A and enters the instrument through the sample introduction structure (3). Then the sample introduction structure (3) moves the test tube (002) to position C to wait for sample aspiration. The sample and reagent robotic arm structure (9) moves to position Q to pick up the sample head (003), while the reaction cup robotic arm structure (10) picks up the reaction cup (001) from position G and places the reaction cup (001) into position D of the mixing mechanism (5). After picking up the sample head (003), the sample and reagent robotic arm structure (9) moves to position C to draw liquid from the test tube (002) and spew the liquid into the reaction cup (001) at position D. The mixing mechanism (5) drives the reaction cup (001) to position E. The sample and reagent robotic arm structure (9) moves to position F to pick up the reagent and spew it into the reaction cup (001) at position E. After the mixing mechanism (5) mixes the sample and reagent, it uses the reaction cup robotic arm structure (10) to pick up the reaction cup (001) and transfer it to position R, and puts it into the loading structure (7) for preheating. After preheating, the reaction cup robotic arm structure (10) transfers the reaction cup (001) to position H and places it into the cleaning mechanism (8) for cleaning and detection of its luminescence value. Finally, the reaction cup robotic arm structure (10) removes the reaction cup (001) from the cleaning mechanism (8) and transfers it to position N for disposal into position K. At the same time, the sample and reagent robotic arm structure (9) transfers the used sample suction head (003) to position J for disposal into position K. When the sample to be tested is whole blood and needs to be tested for HCT, the test tube rack (004) containing the whole blood sample (002) to be tested is placed at position A and enters the instrument through the sample introduction structure (3). The sample introduction structure (3) includes a tube clamping mechanism (3-4), which can clamp the test tube (002). The shaking and opening structure (4) is arranged on the sample introduction structure (3) and performs mixing and opening actions on the test tube (002). Then, the sample introduction structure (3) moves the test tube (002) to position C to wait for sample aspiration. After the sample and reagent robotic arm structure (9) reaches position Q to pick up the sampling head (003), it moves directly to the shaken and opened test tube (002) to aspirate the sample, and then moves to position M to spit the sample into the whole blood sample HCT detection structure (6) for detection.

2. The fully automated chemiluminescence analyzer according to claim 1, characterized in that: The sample introduction structure (3) includes a sample introduction frame (3-1), on which a sample introduction transverse movement device (3-2), a sample introduction longitudinal movement device (3-3), and the tube clamping mechanism (3-4) are provided. The sample introduction transverse device (3-2) is provided with a slidably connected test tube rack loading tray (3-5), and the test tube rack (004) that can be slidably removed is placed in the test tube rack loading tray (3-5). The longitudinal injection device (3-3) is arranged on one side of the transverse injection device (3-2), the tube clamping mechanism (3-4) is arranged transversely on the longitudinal injection device (3-3), and the shaking and opening structure (4) is arranged above the tube clamping mechanism (3-4).

3. The fully automated chemiluminescence analyzer according to claim 2, characterized in that: The bottom of the test tube rack (004) is provided with a test tube rack groove (004-1), and multiple rows of the test tube racks (004) are placed side by side on the test tube rack loading tray (3-5); The sample loading rack (3-1) includes a base plate (3-1.1), on which a vertical plate (3-1.2) is fixedly mounted. An auxiliary slide rail (3-1.3) and a transverse slide rail (3-1.4) are provided on the upper part of the vertical plate (3-1.2). The test tube rack groove (004-1) is slidably connected to the transverse slide rail (3-1.4). The sample introduction transverse movement device (3-2) includes a transverse movement motor (3-2.1) and a transverse movement driven wheel (3-2.3) mounted on the vertical plate (3-1.2). The transverse movement motor (3-2.1) and the transverse movement driven wheel (3-2.3) are connected by a transverse movement synchronous belt (3-2.4). A transverse movement belt clamp (3-2.5) is fixedly connected to the transverse movement synchronous belt (3-2.4). The transverse movement belt clamp (3-2.5) is fixedly connected to the bottom of the transverse movement slide plate (3-2.6). The transverse movement slide plate (3-2.6) is fixedly connected to the bottom of the test tube rack loading tray (3-5). The transverse movement slide plate (3-2.6) is slidably connected to the auxiliary slide rail (3-1.3) by means of a slide groove.

4. The fully automated chemiluminescence analyzer according to claim 3, characterized in that: The vertical plate (3-1.2) and the transverse slide rail (3-1.4) are provided with sliding outlets (3-1.5). The sample injection longitudinal movement device (3-3) includes a sample injection fixing plate (3-3.1) and a sample injection channel (3-3.2); The sample inlet channel (3-3.2) is provided with the tube clamping mechanism (3-4) on both sides. The position of the sample inlet channel (3-3.2) corresponds to the sliding outlet (3-1.5). The sample inlet channel (3-3.2) is slidably engaged with the test tube rack (004). The sample injection fixing plate (3-3.1) is located below the sample injection channel (3-3.2). The sample injection fixing plate (3-3.1) is equipped with a longitudinal movement motor (3-3.3) and a longitudinal movement driven wheel (3-3.5) connected by a longitudinal movement synchronous belt (3-3.6). A longitudinal movement fixing plate (3-3.7) is fixedly connected to the longitudinal movement synchronous belt (3-3.6). The longitudinal movement fixing plate (3-3.7) is slidably connected to the sample injection fixing plate (3-3.1) by means of a slide rail groove. The upper part of the longitudinal moving fixing plate (3-3.7) is fixedly connected with a hook (3-3.8), which is slidably arranged at the bottom of the sample inlet channel (3-3.2). The hook (3-3.8) is engaged with the test tube rack groove (004-1).

5. The fully automated chemiluminescence analyzer according to claim 4, characterized in that: The tube clamping mechanism (3-4) includes a tube clamping motor (3-4.6), a tube clamping base plate (3-4.1), and two portal plates (3-4.2). Two portal plates (3-4.2) are arranged on both sides of the sample inlet channel (3-3.2). A tube clamping plate (3-4.3) is provided on the top of the portal plate (3-4.2). The bottoms of the two portal plates (3-4.2) are respectively fixedly connected to two sliding blocks (3-4.4). The two sliding blocks (3-4.4) are slidably connected to the tube clamping base plate (3-4.1). The two sliding blocks (3-4.4) are threaded onto the bidirectional threaded screw (3-4.5), and one end of the bidirectional threaded screw (3-4.5) is powered by the clamping motor (3-4.6).

6. The fully automated chemiluminescence analyzer according to claim 1, characterized in that: The shaking and opening structure (4) includes a lifting mechanism (4-1), and a swing mechanism (4-2) is provided on the lifting mechanism (4-1). The swing mechanism (4-2) includes a swing frame (4-2.1), which is mounted on the lifting mechanism (4-1). One end of the swing frame (4-2.1) is equipped with a swing motor (4-2.2), and the other end of the swing frame (4-2.1) is equipped with an electric gripper (4-3) that is rotatably connected. The output end of the swing motor (4-2.2) is fixedly connected to a long threaded rod (4-2.3), and a swing drive block (4-2.4) is threadedly connected to the long threaded rod (4-2.3). The swing drive block (4-2.4) is slidably connected to the swing frame (4-2.1) by means of a slide rail and a slide groove. The electric gripper (4-3) is rotatably connected to the front end of the swing frame (4-2.1) via a rotating shaft (4-3.1). The rotating shaft (4-3.1) passes through the swing frame (4-2.1) and is fixedly connected to a first swing rod (4-2.5). The other end of the first swing rod (4-2.5) is rotatably connected to one end of a second swing rod (4-2.6). The other end of the second swing rod (4-2.6) is rotatably connected to the swing drive block (4-2.4).

7. The fully automated chemiluminescence analyzer according to claim 1, characterized in that: The cleaning mechanism (8) includes a cleaning chamber (8-1), a rotating disk (8-3), a suction needle (8-8), and a discharge needle (8-10). The side wall of the cleaning chamber (8-1) is also provided with a photon counter (8-11) for detecting the solution in the reaction cup (001) inside the cleaning chamber (8-1). The top cover of the cleaning chamber (8-1) is equipped with an inlet shielding mechanism (8-2). The aspiration needle (8-8) is connected to the aspiration needle lifting mechanism (8-9); The rotating disk (8-3) is arranged inside the cleaning chamber (8-1). A rotating drive mechanism (8-7) is provided at the bottom of the cleaning chamber (8-1). The rotating drive mechanism (8-7) is connected to the rotating disk (8-3). A magnetic chuck (8-14) is provided below the rotating disk (8-3). A magnetic chuck (8-14) is provided on the magnetic chuck (8-14). The rotating disk (8-3) is provided with a plurality of inverted conical slots (8-4) arranged in a ring. The inverted conical slots (8-4) have a structure that is smaller at the top and larger at the bottom. The outer wall of the reaction cup (001) is provided with a retaining edge (001-1). The reaction cup (001) is placed in the inverted conical slots (8-4), and the retaining edge (001-1) is secured on the rotating disk (8-3). Below the rotary disk (8-3) is a swing drive disk (8-5), which is poweredly connected to the top support mechanism (8-12) and the swing drive mechanism (8-6).

8. The fully automated chemiluminescence analyzer according to claim 7, characterized in that: The suction needle lifting mechanism (8-9) includes a suction needle frame (8-9.1) and a suction needle drive motor (8-9.3). The upper end of the suction needle (8-8) is mounted on the suction needle frame (8-9.1), and the lower end of the suction needle frame (8-9.1) is fixedly connected to the suction needle slide plate (8-9.2). The suction needle slide plate (8-9.2) is vertically slidably connected to the side wall of the cleaning chamber (8-1) by means of a slide rail groove. The suction needle drive motor (8-9.3) is vertically arranged on the bottom plate of the cleaning chamber (8-1). A vertical screw (8-9.4) is fixedly installed on the output shaft of the suction needle drive motor (8-9.3). A lifting sleeve (8-9.5) is threaded onto the vertical screw (8-9.4). The lifting sleeve (8-9.5) is fixedly connected to the suction needle slide plate (8-9.2).

9. The fully automated chemiluminescence analyzer according to claim 8, characterized in that: The swing drive disk (8-5) includes an annular disk (8-5.1), on which a plurality of top supports (8-5.2) are provided. The top supports (8-5.2) have grooves for supporting the reaction cup (001) at eccentric positions. The top supports (8-5.2) correspond to the position of the reaction cup (001) below the spit needle (8-10). The bottom surface of the annular disk (8-5.1) is connected to the top support mechanism (8-12). The top support mechanism (8-12) includes a top support connecting plate (8-12.1). The top end of the top support connecting plate (8-12.1) is fixedly connected to the liquid suction needle slide plate (8-9.2). The bottom end of the top support connecting plate (8-12.1) is fixedly connected to the lower support frame (8-12.2) arranged below the cleaning chamber (8-1). The lower support frame (8-12.2) is provided with a top support shaft (8-12.3). The top support shaft (8-12.3) is slidably connected to the bottom plate of the cleaning chamber (8-1) by means of a linear bearing. The top end of the top support shaft (8-12.3) passes through the bottom plate of the cleaning chamber (8-1) and is fixedly connected to the bottom surface of the annular disk (8-5.1).

10. The fully automated chemiluminescence analyzer according to claim 9, characterized in that: The swing drive mechanism (8-6) includes a top support rotating shaft (8-6.1). The top end of the top support rotating shaft (8-6.1) is fixedly connected to the lower end face of the top support seat (8-5.2). The shaft body of the top support rotating shaft (8-6.1) is rotatably connected to the annular disk (8-5.1). The bottom end of the top support rotating shaft (8-6.1) passes through the annular disk (8-5.1) and is fixedly provided with a rotating pulley (8-6.2). The rotating pulley (8-6.2) is connected to the output end of the swing drive motor (8-6.3) through a synchronous belt. The swing drive motor (8-6.3) is fixedly connected to the annular disk (8-5.1).

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