Natural compound preparation with synergistic formaldehyde removal function as well as preparation method and application of natural compound preparation
By using carnosine and EGCG in a natural compound preparation to covalently react with aldehydes, the threat of aldehyde molecules to chefs' health during high-temperature cooking is solved, achieving a safe and low-cost aldehyde removal effect.
Patent Information
- Application Number
- CN202511857088.3
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-12-10
- Publication Date
- 2026-02-17
AI Technical Summary
During high-temperature cooking, aldehyde molecules produced by the oxidation of unsaturated fatty acids in cooking oil undergo Michael addition reactions with biomolecules, leading to cytotoxicity, neurotoxicity, and genotoxicity in high-risk groups such as chefs, which can have long-term health effects.
A natural compound formulation is used, consisting of carnosine, epigallocatechin gallate, surfactant and solvent. It removes aldehydes at room temperature and kitchen oil fume temperature through covalent reaction. The amino group of the main component carnosine undergoes Michael addition reaction with the carbonyl group of aldehydes, and the phenolic hydroxyl group of EGCG captures aldehydes.
It effectively reduces the risk of aldehyde exposure for groups such as chefs, protects their health, and the preparation method is safe, low-cost, and produces no harmful byproducts, making it suitable for widespread application.
Smart Images
Figure CN121534530A_ABST
Abstract
Description
Technical Field
[0001] This invention relates to the field of food processing safety and environmental pollution control technology, specifically to a natural compound preparation with synergistic aldehyde removal function, its preparation method, and its application. Background Technology
[0002] Commonly available cooking oils are high in unsaturated fatty acids such as linoleic acid, oleic acid, and alpha-linolenic acid. These fatty acids are easily oxidized during high-temperature cooking, especially stir-frying and deep-frying, producing a large number of secondary oxidation products such as aldehydes. Among these, acrolein, propionaldehyde, HNE, and HHE are highly reactive and can undergo Michael addition reactions with biomolecules in the body, such as proteins (amino acids), aminophospholipids, nucleic acids, and even endogenous antioxidants like glutathione, interfering with their physiological activity. This can cause significant cytotoxicity, neurotoxicity, and genotoxicity in high-risk groups such as chefs. Long-term intake and exposure may induce diabetes and cardiovascular diseases, causing serious public health problems. Summary of the Invention
[0003] To address the shortcomings of the existing technologies, the present invention aims to provide a natural compound preparation with synergistic aldehyde removal function, its preparation method, and its application. This invention aims to reduce the exposure risk to specific groups such as chefs and protect their health. The main component, carnosine, is a dipeptide that can be used as a food additive and has good antioxidant activity. The amino group in its structure can undergo a Michael addition reaction with the carbonyl group of aldehydes. Epigallocatechin gallate is a common polyphenol, and its phenolic hydroxyl group can "capture" and remove aldehydes through reaction.
[0004] To solve the above-mentioned technical problems, the present invention adopts the following technical solution: A natural compound preparation with synergistic formaldehyde removal function is composed of the following raw materials in the indicated mass fractions: 5%-10% carnosine, 0.5%-2% epigallocatechin gallate, 0.05%-0.2% food flavoring, 10%-20% surfactant, and the remainder is solvent, totaling 100%; the pH of the natural compound preparation is 7.0-9.0.
[0005] A method for preparing a natural compound preparation with synergistic formaldehyde removal function includes the following steps: Carnosine and epigallocatechin gallate were added to a solvent and mixed to obtain a dispersion.
[0006] A surfactant is added to the dispersion and heated to obtain a mixture.
[0007] After cooling the mixture, add edible flavoring, then add food-grade sodium bicarbonate to adjust the pH, thus obtaining a natural compound preparation with synergistic formaldehyde removal function.
[0008] In a preferred embodiment of the present invention, the solvent is a mixed solution of deionized water and ethanol, wherein the volume fraction of ethanol in the solvent is 5%-15%.
[0009] In a preferred embodiment of the present invention, the surfactant is sodium α-alkenylsulfonate and sodium cocoyl ether carboxylate, wherein the mass fraction of sodium α-alkenylsulfonate and sodium cocoyl ether carboxylate is 5%-10%.
[0010] In a preferred embodiment of the present invention, the pH is adjusted to 7.0-9.0.
[0011] In a preferred embodiment of the present invention, the heating and mixing temperature is 35°C-50°C.
[0012] The application of the natural compound preparation with synergistic formaldehyde removal function described in this invention in removing harmful active aldehydes from kitchen fumes.
[0013] The application of the natural compound preparation with synergistic formaldehyde removal function described in this invention in removing harmful active aldehydes in kitchen fumes, wherein the harmful active aldehydes in kitchen fumes are acrolein, propionaldehyde, hexanal, 4-hydroxynonenal and 4-hydroxyhexenal.
[0014] Compared with the prior art, the beneficial effects of the present invention are: 1. The active ingredients in the natural compound preparation prepared by this invention can undergo covalent reactions with aldehydes at room temperature and kitchen oil fume temperatures, reducing the exposure risk to specific groups such as chefs and ensuring their health. The main component, carnosine, is a dipeptide that can be used as a food additive and has good antioxidant activity. The amino group in its structure can undergo Michael addition reaction with the carbonyl group of aldehydes. EGCG is a common polyphenol, and its phenolic hydroxyl group can "capture" and remove aldehydes by reacting with them, thus having a synergistic aldehyde removal function.
[0015] 2. The preparation method of the natural compound preparation with synergistic formaldehyde removal function described in this invention requires safe and inexpensive raw materials, has low energy consumption throughout the process, is simple to operate and easy to implement, and does not produce harmful by-products or secondary pollution. It is safe and non-toxic to the human body and is suitable for widespread application. Attached Figure Description
[0016] Figure 1 This is a flowchart illustrating the preparation process of the natural compound preparation with synergistic formaldehyde removal function of the present invention. Detailed Implementation
[0017] The following detailed description, in conjunction with embodiments of the present invention and accompanying drawings, provides a clear and complete illustration of the technical solutions in these embodiments. Obviously, the described embodiments are only a part of the embodiments of the present invention, and not all of them. All other embodiments obtained by those skilled in the art based on the embodiments of the present invention without creative effort are within the scope of protection of the present invention.
[0018] It should be noted that all technical terms used in this invention are for the purpose of describing specific embodiments only and are not intended to limit the scope of protection of this invention. Unless otherwise specified, all raw materials, reagents, instruments and equipment used in the following embodiments of this invention can be purchased from the market or prepared by existing methods.
[0019] Figure 1 The flowchart illustrates the preparation process of the natural compound formulation with synergistic formaldehyde removal function of this invention. Carnosine and EGCG are added to a solvent and mixed to obtain a dispersion. A surfactant is added to the dispersion and heated to obtain a mixture. After cooling the mixture, edible flavoring is added, followed by the addition of food-grade sodium bicarbonate to adjust the pH value, thus obtaining the natural compound formulation with synergistic formaldehyde removal function.
[0020] A natural compound preparation with synergistic formaldehyde removal function is composed of the following raw materials in the indicated mass fractions: 5%-10% carnosine, 0.5%-2% epigallocatechin gallate, 0.05%-0.2% food flavoring, 10%-20% surfactant, and the remainder being solvent.
[0021] A method for preparing a natural compound preparation with synergistic formaldehyde removal function includes the following steps: Carnosine and epigallocatechin gallate were added to a solvent and mixed to obtain a dispersion.
[0022] A surfactant is added to the dispersion and heated to obtain a mixture.
[0023] After cooling the mixture, add edible flavoring, then add food-grade sodium bicarbonate to adjust the pH, thus obtaining a natural compound preparation with synergistic formaldehyde removal function.
[0024] In a preferred embodiment of the present invention, the solvent is a mixed solution of deionized water and ethanol, wherein the volume fraction of ethanol in the solvent is 5%-15%.
[0025] In a preferred embodiment of the present invention, the surfactant is sodium α-alkenylsulfonate and sodium cocoyl ether carboxylate, wherein the mass fraction of sodium α-alkenylsulfonate and sodium cocoyl ether carboxylate is 5%-10%.
[0026] In a preferred embodiment of the present invention, the pH is adjusted to 7.0-9.0.
[0027] In a preferred embodiment of the present invention, the heating and mixing temperature is 35°C-50°C.
[0028] Example 1: A method for preparing a natural compound preparation with synergistic formaldehyde removal function includes the following steps: (1) An ethanol aqueous solution was prepared by adding 5% ethanol by volume to deionized water as a solvent.
[0029] (2) Add carnosine and EGCG sequentially to the ethanol aqueous solution in (1) so that their mass fractions are 5% and 0.5% respectively. After thorough stirring, a homogeneous and stable solution is obtained.
[0030] (3) Add 5% sodium α-alkenyl sulfonate and 7% sodium cocoyl ether carboxylate to the solution prepared in (2), heat the solution to 40°C, and stir thoroughly to obtain a stable homogeneous solution.
[0031] (4) Fragrance blending: Cool the solution prepared in (3) to room temperature, add 0.10% of a specific fragrance food flavoring and mix thoroughly.
[0032] (5) Add food-grade sodium bicarbonate to the mixture prepared in (4) and adjust the pH of the system to 7.5.
[0033] (6) Performance: The mixed formulation prepared by the above steps was reacted with four representative active aldehydes (acrylaldehyde, hexanal, HHE, HNE). After 10 min, the amount of the above aldehydes was reduced by 39.6%-52.4%.
[0034] Example 2: A method for preparing a natural compound preparation with synergistic formaldehyde removal function includes the following steps: (1) An ethanol aqueous solution was prepared by adding 10% ethanol by volume to deionized water as a solvent.
[0035] (2) Add carnosine and EGCG sequentially to the ethanol aqueous solution in (1) so that their mass fractions are 8% and 1% respectively. After thorough stirring, a homogeneous and stable solution is obtained.
[0036] (3) Add 8% sodium α-alkenyl sulfonate and 5% sodium cocoyl ether carboxylate to the solution prepared in (2), heat the solution to 50°C, and stir thoroughly to obtain a stable homogeneous solution.
[0037] (4) Fragrance blending: Cool the solution prepared in (3) to room temperature, add 0.15% of a specific fragrance food flavoring and mix thoroughly.
[0038] (5) Add food-grade sodium bicarbonate to the mixture prepared in (4) and adjust the pH of the system to 8.0.
[0039] (6) Performance: The mixed formulation prepared by the above steps was reacted with four representative active aldehydes (acrylaldehyde, hexanal, HHE, HNE). After 10 min, the amount of the above aldehydes was reduced by 42.6%-64.8%.
[0040] Example 3 A method for preparing a natural compound preparation with synergistic formaldehyde removal function includes the following steps: (1) An ethanol aqueous solution was prepared by adding 15% ethanol by volume to deionized water as a solvent.
[0041] (2) Add carnosine and EGCG sequentially to the ethanol aqueous solution in (1) so that their mass fractions are 10% and 2% respectively. After thorough stirring, a homogeneous and stable solution is obtained.
[0042] (3) Add 10% sodium α-alkenyl sulfonate and 5% sodium cocoyl ether carboxylate to the solution prepared in (2), heat the solution to 50°C, and stir thoroughly to obtain a stable homogeneous solution.
[0043] (4) Fragrance blending: Cool the solution prepared in (3) to room temperature, add 0.10% of a specific fragrance food flavoring and mix thoroughly.
[0044] (5) Add food-grade sodium bicarbonate to the mixture prepared in (4) and adjust the pH of the system to 8.5.
[0045] (6) Performance: The mixed formulation prepared by the above steps was reacted with four representative active aldehydes (acrylaldehyde, hexanal, HHE, HNE). After 10 min, the amount of the above aldehydes was reduced by 50.5%-73.2%.
[0046] Comparative Example 1: (1) The existing mainstream formaldehyde removal methods are mainly based on physical adsorption. Compared with Example 3, 350g of crushed peanut shells were added to a zinc chloride solution with a mass fraction of 40% (material-liquid ratio 1:2) and mixed evenly. The mixture was then activated in a 30℃ water bath for 12h.
[0047] (2) Then place it in a muffle furnace at 400℃ for 4 hours to carbonize. After cooling to room temperature, wash it with 3 mol / L hydrochloric acid and then wash it with distilled water until the pH value is 6. Dry, grind and pass through an 80-mesh sieve to obtain peanut shell activated carbon.
[0048] (3) The formaldehyde removal rate of the peanut shell activated carbon can reach 81.27%.
[0049] Comparative Example 2: Compared with Example 1, the standard method was used for preparation, but in (2) no carnosine was added to prepare the compound preparation, specifically: (1) An ethanol aqueous solution was prepared by adding 5% ethanol by volume to deionized water as a solvent.
[0050] (2) Add EGCG to the ethanol aqueous solution in (1) to make the mass fraction of EGCG 0.5% and mix thoroughly to obtain a homogeneous and stable solution.
[0051] (3) Add 5% sodium α-alkenyl sulfonate and 7% sodium cocoyl ether carboxylate to the solution prepared in (2), heat the solution to 40°C, and stir thoroughly to obtain a stable homogeneous solution.
[0052] (4) Fragrance blending: Cool the solution prepared in (3) to room temperature, add 0.10% of a specific fragrance food flavoring and mix thoroughly.
[0053] (5) Add food-grade sodium bicarbonate to the mixture prepared in (4) and adjust the pH of the system to 7.5.
[0054] (6) The mixed formulation prepared by the above steps was reacted with four representative active aldehydes (acrylaldehyde, hexanal, HHE, HNE). After 10 min, the amount of the above aldehydes was reduced by 31.6%-44.4%.
[0055] Results Analysis The natural composite preparation with synergistic formaldehyde removal function prepared in Example 1 reacted with four representative active aldehydes (acrylonitrile, hexanal, HHE, and HNE) for 10 min, and the reduction of the above aldehydes was 39.6%-52.4%. The natural composite preparation with synergistic formaldehyde removal function prepared in Example 2 reacted with four representative active aldehydes (acrylonitrile, hexanal, HHE, and HNE) for 10 min, and the reduction of the above aldehydes was 42.6%-64.8%. The natural composite preparation with synergistic formaldehyde removal function prepared in Example 2 reacted with four representative active aldehydes (acrylonitrile, hexanal, HHE, and HNE) for 10 min, and the reduction of the above aldehydes was 50.5%-73.2%. Therefore, it is shown that the natural composite preparation prepared in this invention has a synergistic formaldehyde removal function.
[0056] Table 1. Characteristics of methods for removing aldehydes from cooking fumes. The preparation method of the natural compound preparation with synergistic formaldehyde removal function described in this invention requires safe and inexpensive raw materials, has low energy consumption throughout the process, is simple to operate and easy to implement, and does not produce harmful by-products or secondary pollution. It is safe and non-toxic to the human body and is suitable for widespread application.
[0057] The active ingredients in the natural compound preparation prepared by this invention can undergo covalent reactions with aldehydes at room temperature and kitchen fumes, reducing the exposure risk to specific groups such as chefs and ensuring their health. The main component, carnosine, is a dipeptide that can be used as a food additive and has good antioxidant activity. The amino group in its structure can undergo Michael addition reaction with the carbonyl group of aldehydes. EGCG is a common polyphenol, and its phenolic hydroxyl group can "capture" and remove aldehydes by reacting with them, thus having a synergistic aldehyde removal function.
[0058] It should be noted that when numerical ranges are involved in this invention, it should be understood that both endpoints of each numerical range and any value between the two endpoints can be selected. Since the steps and methods used are the same as in the embodiments, preferred embodiments are described here to avoid redundancy. Although preferred embodiments of the invention have been described, those skilled in the art, once they understand the basic inventive concept, can make other changes and modifications to these embodiments. Therefore, the appended claims are intended to be interpreted as including the preferred embodiments as well as all changes and modifications falling within the scope of this invention.
[0059] Obviously, those skilled in the art can make various modifications and variations to this invention without departing from its spirit and scope. Therefore, if these modifications and variations fall within the scope of the claims of this invention and their equivalents, this invention also intends to include these modifications and variations.
Claims
1. A natural compound preparation with synergistic formaldehyde removal function, characterized in that, It is composed of the following raw materials in the following mass fractions: 5%-10% carnosine, 0.5%-2% epigallocatechin gallate, 0.05%-0.2% food flavoring, 10%-20% surfactant, and the remainder is solvent, totaling 100%; the pH of the natural compound preparation is 7.0-9.
0.
2. The preparation method of the natural compound preparation with synergistic formaldehyde removal function according to claim 1, characterized in that, Includes the following steps: Carnosine and epigallocatechin gallate were added to a solvent and mixed to obtain a dispersion. A surfactant is added to the dispersion and heated to obtain a mixture. After cooling the mixture, add edible flavoring, then add food-grade sodium bicarbonate to adjust the pH, thus obtaining a natural compound preparation with synergistic formaldehyde removal function.
3. The natural compound preparation with synergistic formaldehyde removal function according to claim 2, characterized in that, The solvent is a mixture of deionized water and ethanol, with the volume fraction of ethanol in the solvent being 5%-15%.
4. The natural compound preparation with synergistic formaldehyde removal function according to claim 2, characterized in that, The surfactants are sodium α-alkenylsulfonate and sodium cocoyl ether carboxylate. In the natural compound preparation, the mass fraction of sodium α-alkenylsulfonate and sodium cocoyl ether carboxylate is 5%-10%.
5. The method for preparing the natural compound preparation with synergistic formaldehyde removal function according to claim 2, characterized in that, Adjust the pH to 7.0-9.
0.
6. The method for preparing the natural compound preparation with synergistic formaldehyde removal function according to claim 2, characterized in that, The temperature for heating and mixing is 35℃-50℃.
7. The application of the natural compound preparation with synergistic formaldehyde removal function according to claim 1 in removing harmful active aldehydes from kitchen fumes.
8. The application of the natural compound preparation with synergistic formaldehyde removal function according to claim 7 in removing harmful active aldehydes from kitchen fumes, characterized in that, Harmful active aldehydes in kitchen fumes include acrolein, propionaldehyde, hexanal, 4-hydroxynonenal, and 4-hydroxyhexenal.