Coating composition for surgical electrode with electrocision temperature lower than 37 DEG C and surgical electrode

Abstract

The invention discloses a coating composition for an operation electrode with the electric excision temperature lower than 37 DEG C and the operation electrode, and relates to the technical field of electrode coating curing paint. The invention relates to a coating composition for an operation electrode with an electrocision temperature lower than 37 DEG C. The antibacterial coating is prepared from the following components in parts by mass: 25 to 35 parts of epoxy resin, 15 to 25 parts of polyurethane resin, 5 to 10 parts of graphene, 3 to 8 parts of polytetrafluoroethylene powder, 2 to 5 parts of silicon dioxide nanoparticles, 1 to 3 parts of a silane coupling agent, 30 to 50 parts of an organic solvent and 1 to 2 parts of a long-acting antibacterial agent. In order to overcome the defects that an existing antibacterial coating is short in antibacterial time efficiency and prone to proceeding along with an operation or aging failure, the composite coating has long-acting antibacterial capacity, the antibacterial effect can still be well reserved even after multiple times of related aging treatment, the whole operation process can be better covered, and the postoperative infection possibility is reduced.

Description

Technical Field

[0001] This invention relates to the field of electrode coating curing technology, specifically to a coating composition for surgical electrodes with an electrocautery temperature below 37°C and a surgical electrode. Background Technology

[0002] In minimally invasive surgeries such as urology and gynecology, electrosurgical electrodes are core instruments for achieving precise tissue cutting and hemostasis, and their performance directly determines surgical safety and postoperative recovery. During surgery, the electrode surface needs to be in continuous contact with human tissue, and the surgical environment carries the risk of bacterial contamination. If the electrode lacks reliable antibacterial capabilities, bacteria attached to its surface can easily enter the body through the wound, causing postoperative infection. In severe cases, this may lead to surgical failure or trigger a systemic inflammatory response. Therefore, the antibacterial performance of the electrode is one of the core indicators of clinical concern.

[0003] Meanwhile, traditional surgical electrodes often operate at high temperatures during electrosurgical procedures, which not only easily cause thermal damage and carbonization to surrounding normal tissues, but also accelerate the degradation of the antibacterial coating on the electrode surface. Under high temperature conditions, most short-acting antibacterial agents (such as ordinary silver ions and quaternary ammonium salts) are prone to rapid dissolution or decomposition, resulting in a sharp decline in antibacterial effect as the operation time increases, making it difficult to cover the entire surgical cycle. Especially for long and complex surgeries, the risk of antibacterial failure increases significantly.

[0004] Current antibacterial coatings still face several technical bottlenecks: First, their antibacterial effect is short-lived. Most coatings rely on the one-time dissolution of antibacterial components, and lose their antibacterial ability after dissolution, thus failing to provide long-term protection. Second, the coating has weak adhesion to the electrode substrate (such as stainless steel or titanium alloy), and is prone to detachment during surgery due to friction and temperature fluctuations. Detached particles not only lose their antibacterial effect but may also trigger foreign body reactions in the tissue. Third, some antibacterial agents (such as high-concentration silver ions) are biotoxic and may affect the conductivity of the electrode, leading to a decrease in electrocautery efficiency.

[0005] In summary, there is an urgent clinical need for a surgical electrode coating technology that can achieve low electrosurgical temperature, long-lasting and stable antibacterial properties, strong coating adhesion, excellent biocompatibility, and does not affect the electrode's conductivity, in order to address the shortcomings of existing products such as short antibacterial duration and insufficient safety. Summary of the Invention

[0006] To address the problems of existing surgical electrodes, such as high electrocautery temperature leading to thermal damage to surrounding tissues, short-lasting antibacterial effect, and easy coating peeling, the present invention aims to provide a coating composition and surgical electrode for surgical electrodes with an electrocautery temperature below 37°C. The coating has a strong bond and long-lasting antibacterial properties, which can avoid tissue damage and ensure antibacterial protection throughout the surgery, thereby improving the safety and reliability of the surgery.

[0007] To achieve the above objectives, the technical solution adopted by the present invention is: a coating composition for a surgical electrode with an electrocautery temperature below 37°C, comprising the following components in parts by weight: 25-35 parts by weight of epoxy resin, 15-25 parts by weight of polyurethane resin, 5-10 parts by weight of graphene, 3-8 parts by weight of polytetrafluoroethylene powder, 2-5 parts by weight of silica nanoparticles, 1-3 parts by weight of silane coupling agent, 30-50 parts by weight of organic solvent, and 1-2 parts by weight of long-lasting antibacterial agent;

[0008] The long-acting antibacterial agent has the structure shown in Formula 1:

[0009] The chemical formula of Formula 1 is: ;

[0010] In Formula 1, R1 is a substituent, and R1 is any one of hydrogen, methyl, ethyl, and chlorine.

[0011] Furthermore, the epoxy resin is a bisphenol A type liquid epoxy resin with an epoxy value of 0.48-0.54 eq / 100g.

[0012] Furthermore, the polyurethane resin is an aqueous polyurethane resin with a solid content of 33.5-35.5% and a viscosity of 500-1,000 mPa·s at 25°C.

[0013] Furthermore, the silane coupling agent is any one of KH550, KH560, and KH570.

[0014] Furthermore, the organic solvent is any one of tetrahydrofuran, N-ethylpyrrolidone, and toluene.

[0015] Furthermore, the long-acting antibacterial agent is any one of the compounds shown in the following structures:

[0016] ;

[0017] .

[0018] A surgical electrode with a composite coating and an electrocautery temperature below 37°C, the surgical electrode comprising an electrode substrate and a composite coating coated on its surface;

[0019] The composite coating is prepared from a coating composition for surgical electrodes with an electrosurgical cutting temperature below 37°C;

[0020] The electrode substrate is made of stainless steel or titanium alloy and is in the shape of a sheet, needle, or ring.

[0021] A method for preparing a surgical electrode with a composite coating and an electrocautery temperature below 37°C includes the following steps:

[0022] S1: Dissolve the epoxy resin and polyurethane resin in an organic solvent and stir and mix at 40-60°C for 30-60 minutes to obtain a resin solution;

[0023] S2: Add the graphene, polytetrafluoroethylene powder, silica nanoparticles, silane coupling agent and long-lasting antibacterial agent to the resin solution, and disperse it at 1000-2000 rpm for 60-120 minutes using a high-speed disperser to obtain a uniform coating slurry.

[0024] S3: Apply the coating slurry to the surface of the electrode substrate after the blade has been sharpened. The coating thickness is 50-100μm. Curing treatment is carried out at 80-120℃ for 1-2 hours. The entire electrode surface is covered by the coating, with only the sharpened part of the electrode remaining exposed at the micron level. This results in a surgical electrode with a composite coating and an electric cutting temperature of less than 37℃.

[0025] The entire electrode surface is covered by a coating, with only the electrode blade exposed at the micron level. During use, energy is concentrated at the electrode blade, generating plasma under high frequency and high voltage. The power of the main unit can also be reduced. The traditional 40-60W, the surgical electrode of this invention using a composite coating only uses 5-10W.

[0026] Furthermore, S2 and S3 are carried out under a nitrogen atmosphere.

[0027] Furthermore, the coating in S3 is applied by spraying or dipping, and after coating, it is left to stand for 10-20 minutes to allow it to level.

[0028] Furthermore, the curing process in S3 is divided into two stages: first, curing at 80°C for 30 minutes, and then curing at 120°C for 1 hour.

[0029] This invention utilizes an interpenetrating polymer network formed by epoxy resin and polyurethane resin as a coating framework, combining rigidity and flexibility. The epoxy resin provides high adhesion and hardness to ensure a firm bond between the coating and the metal electrode substrate, while the polyurethane resin imparts flexibility and wear resistance to prevent cracking. Within this framework, graphene, with its extremely high thermal conductivity, constructs a rapid heat dissipation pathway, while polytetrafluoroethylene powder achieves lubrication and friction reduction through its extremely low coefficient of friction. Together, they effectively control the electro-cutting temperature below 37°C by enhancing heat dissipation and reducing heat generation. Simultaneously, a uniquely structured long-lasting antibacterial agent is stably embedded within the resin matrix. It works through a contact antibacterial mechanism, and its long-lasting effect is due to the robust coating skeleton that prevents it from being lost, while the low-temperature environment ensures its chemical stability. Furthermore, silica nanoparticles, as reinforcing fillers, improve the coating's hardness, wear resistance, and density, while silane coupling agents build molecular bridges between the inorganic matrix / filler and the organic resin, significantly enhancing the coating's adhesion and internal compatibility. Finally, through precise formulation, the components systematically achieve a synergistic effect of low-temperature cutting, long-lasting antibacterial effect, and high-bonding-strength coating, solving the three core technical challenges of high electro-cutting temperature, short antibacterial duration, and easy coating peeling.

[0030] Compared with the prior art, the beneficial effects of the present invention are:

[0031] 1. Superior and stable electrosurgical temperature control: Compared with the problem of high electrosurgical temperature in traditional surgical electrodes in the prior art, the present invention can effectively control the electrosurgical temperature at a lower level, and the temperature can remain stable after aging treatment, which can reduce the risk of thermal damage to surrounding normal tissues.

[0032] 2. Longer-lasting antibacterial performance: In view of the shortcomings of existing antibacterial coatings, such as short antibacterial time and easy failure during surgery or due to aging, the composite coating of the present invention has long-lasting antibacterial ability. Even after multiple aging-related treatments, the antibacterial effect can still be well preserved, which can better cover the entire surgical process and reduce the possibility of postoperative infection.

[0033] 3. Stronger and more durable coating: Overcoming the problems of weak adhesion and easy peeling of existing coatings to the electrode substrate, the composite coating formed by the combination of components in this invention has a tighter bond with the electrode substrate, while also having a certain degree of wear resistance. It is not easy to peel off due to friction or temperature fluctuations during surgery, and does not affect the normal conductivity of the electrode, thus improving the overall reliability of the electrode. Attached Figure Description

[0034] Figure 1 This is the NMR spectrum of the long-acting antibacterial agent 1 described in this invention.

[0035] Figure 2 This is the NMR spectrum of the long-acting antibacterial agent 4 described in this invention.

[0036] Figure 3 This is a schematic diagram of the surgical electrode blade model described in this invention.

[0037] Figure 4 This is a schematic diagram of the surgical electrode blade and the tissue cutting surface described in this invention. Detailed Implementation

[0038] The technical solution of the present invention will now be clearly and completely described with reference to the accompanying drawings. Obviously, the described embodiments are merely some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0039] Preparation Example 1

[0040] Preparation of long-acting antibacterial agent 1:

[0041] ;

[0042] .

[0043] CAS number of compound 1: 78562-62-6;

[0044] CAS number of compound 2: 2919493-08-4;

[0045] The CAS number for compound 4 is 1120-87-2.

[0046] Under a nitrogen atmosphere, 10 g of compound 1, 5.38 g of compound 2, and 8.15 g of anhydrous potassium carbonate were added sequentially to the reaction system, dissolved in 120 mL of a toluene-water mixture (2:1 v / v). The nitrogen atmosphere was then purged twice. Under nitrogen protection, 1.35 g of tris(dibenzylacetone)palladium and 0.30 g of tri-tert-butylphosphine were added to the reaction system, and the nitrogen atmosphere was purged twice. The mixture was heated to 105 °C and refluxed for 10 hours. Heating was then stopped, and the mixture was cooled to room temperature. The mixture was allowed to stand and separated. The aqueous phase was extracted twice with ethyl acetate. The organic phases were combined, washed three times with water, and evaporated to dryness. Silica gel column chromatography was performed using a mixture of petroleum ether and ethyl acetate as eluent. The solution was evaporated to dryness to give 8.63 g of compound 3. The mass spectrometry of the compounds was analyzed by MS+H. + 367.

[0047] Under a nitrogen atmosphere, 8.63 g of compound 3, 4.47 g of compound 4, 4.53 g of sodium tert-butoxide, and 100 ml of toluene were added sequentially to the reaction system. The mixture was stirred until homogeneous, then 0.36 g of tetrakis(triphenylphosphine)palladium was added. The mixture was heated to 120 °C and refluxed for 12 h. After the reaction was complete, the temperature was slightly lowered, and the mixture was filtered through diatomaceous earth to remove salts and catalysts. The filtrate was cooled to room temperature, washed three times with water, and the organic phase was retained. The aqueous phase was then extracted with ethyl acetate. The combined organic phases were dried over anhydrous magnesium sulfate, and the solvent was removed using a rotary evaporator. The mixture was evaporated to dryness, and silica gel column chromatography was performed using a mixture of petroleum ether and ethyl acetate as eluent. The resulting product was evaporated to dryness to obtain 8.08 g of the long-acting antibacterial agent 1. The compound was analyzed by mass spectrometry (MS+H). + :444, see MRI Figure 1 .

[0048] Preparation Examples 2-4

[0049] In Preparation Examples 2-4, long-acting antibacterial agents 2-4 were prepared sequentially, following the preparation method of Preparation Example 1, except that compound 4 was replaced, and the rest remained the same as in Preparation Example 1. See Table 1 for details.

[0050] Table 1

[0051]

[0052] Example 1

[0053] Preparation of a surgical electrode with a composite coating and an electrocautery temperature below 37°C:

[0054] 1. Raw material components:

[0055] Epoxy resin: Bisphenol A type liquid epoxy resin, epoxy value 0.51-0.54 eq / 100g, purchased from: Shandong Deyuan Epoxy Technology Co., Ltd.;

[0056] Polyurethane resin: Waterborne polyurethane resin, solid content 33.5-35.5%, viscosity at 25℃ 500-1000 mPa·s, purchased from: Arakawa Chemical Synthesis (Shanghai) Co., Ltd.

[0057] Graphene: Graphene powder, specific surface area: 180-280 m² 2 / g, purchased from: Changzhou Sixth Element Materials Technology Co., Ltd.;

[0058] Polytetrafluoroethylene (PTFE) powder: PTFE ultrafine powder, particle size distribution: D50: <3.5µm, D90: <6.0µm, purchased from: Fuzhou Taipuda New Materials Co., Ltd.;

[0059] Silica nanoparticles, particle size: 15±5nm, purchased from: Hangzhou Hengge Technology Co., Ltd.

[0060] Silane coupling agent: KH560, purchased from: Sinopharm Chemical Reagent Co., Ltd.;

[0061] Organic solvent: N-ethylpyrrolidone, purchased from: Shanghai Maclean Biochemical Technology Co., Ltd.;

[0062] Long-acting antibacterial agent: Long-acting antibacterial agent 1 prepared according to Preparation Example 1 of the present invention.

[0063] 2. Electrode substrate specifications: 304 stainless steel is selected as the electrode substrate material. The substrate is sheet-shaped with the following specific dimensions: width 2.1mm, effective working length 18cm, and the cutting edge is only sharpened. The substrate surface is pre-treated by sandblasting (80-mesh abrasive), ultrasonic cleaning (ethanol as cleaning agent, cleaning time 20 minutes), and drying (80℃ drying for 30 minutes) to ensure that the surface is free of oil, oxide layer and impurities.

[0064] 3. Preparation steps of composite-coated surgical electrodes:

[0065] S1. In a 500mL three-necked flask, add 30 parts by weight of bisphenol A type liquid epoxy resin, 20 parts by weight of waterborne polyurethane resin, and 40 parts by weight of N-ethylpyrrolidone in sequence; place the three-necked flask in a constant temperature water bath, set the temperature to 50℃, turn on the mechanical stirrer (stirrer speed 300rpm), and stir continuously for 45 minutes until the resin is completely dissolved and a homogeneous, transparent resin solution is formed. During this period, high-purity nitrogen gas (purity ≥99.99%) is introduced into the flask through a nitrogen gas delivery tube to maintain a nitrogen atmosphere;

[0066] S2. Maintain a nitrogen atmosphere and a water bath temperature of 50°C in the three-necked flask. Add 8 parts by mass of graphene, 5 parts by mass of polytetrafluoroethylene powder, 3 parts by mass of silica nanoparticles, 2 parts by mass of KH560 silane coupling agent, and 1.5 parts by mass of long-acting antibacterial agent 1 to the above resin solution in sequence. Replace the stirring device with a high-speed disperser (dispersion disc diameter 50mm), set the speed to 1500rpm, and continue dispersing for 90 minutes. During this period, take samples every 30 minutes to observe the uniformity of the slurry to ensure that there is no obvious particle agglomeration. Finally, a black, uniform coating slurry without precipitation is obtained.

[0067] S3. Using air spraying (spray gun model W-71, nozzle diameter 0.5mm, spraying pressure 0.3MPa, spraying distance 15cm), the above coating slurry is uniformly coated onto the surface of the pretreated stainless steel needle electrode substrate. The coating thickness is adjusted by controlling the number of sprays (3 times). After coating, the electrode is placed on a horizontal flat platform and left to stand at room temperature (25℃) in a nitrogen atmosphere for 15 minutes to allow the coating to flow naturally and avoid defects such as sagging and pinholes.

[0068] Curing process: The leveled electrode is transferred to a programmed temperature oven and a nitrogen atmosphere is maintained. A two-stage curing process is performed: in the first stage, the temperature is raised to 80°C and held for 30 minutes; in the second stage, the temperature is raised to 120°C and held for 1 hour. After curing, the oven is turned off and the electrode is allowed to cool naturally to room temperature (25°C). The electrode is then removed and the cutting edge is treated to obtain a surgical electrode with a composite coating that has an electrical cutting temperature of less than 37°C.

[0069] Examples 2-4

[0070] The preparation of a surgical electrode with a composite coating and an electrocautery temperature below 37°C is carried out in accordance with the preparation of Example 1, except that the long-acting antibacterial agent is replaced sequentially with long-acting antibacterial agent 2-long-acting antibacterial agent 4, and the rest is the same as in Example 1.

[0071] Comparative Example 1

[0072] The preparation of a surgical electrode with a composite coating and an electrocautery temperature below 37°C is described, referring to the preparation method in Example 1, except that the long-acting antibacterial agent is replaced with: (Commonly used quinolone antibacterial agents), the rest is the same as in Example 1.

[0073] Comparative Example 2

[0074] The preparation of a surgical electrode with a composite coating and an electrocautery temperature below 37°C is carried out in accordance with the preparation of Example 1, except that the long-acting antibacterial agent is replaced with benzalkonium chloride, and the rest is the same as in Example 1.

[0075] Comparative Example 3

[0076] The preparation of a surgical electrode with a composite coating and an electrocautery temperature below 37°C is described in accordance with the preparation of Example 1, except that the long-acting antibacterial agent is replaced with silver nitrate, and the rest is the same as in Example 1.

[0077] Comparative Example 4

[0078] The preparation of a surgical electrode with a composite coating and an electrocautery temperature below 37°C is the same as that in Example 1, except that the long-acting antibacterial agent is not added.

[0079] Comparative Example 5

[0080] The preparation of a surgical electrode with a composite coating and an electrocautery temperature below 37°C is the same as in Example 1, except that the polytetrafluoroethylene (PTFE) powder is not added.

[0081] Comparative Example 6

[0082] The preparation of a surgical electrode with a composite coating and an electrocautery temperature below 37°C is the same as that in Example 1, except that graphene is not added.

[0083] Performance testing:

[0084] 1. Electrical cutting temperature test:

[0085] 1.1 Test Equipment and Materials

[0086] Equipment: High-frequency electrosurgical unit (output power adjustable range 50-120W), infrared thermal imager (resolution ≥640×512, temperature measurement range 0-100℃, accuracy ±0.1℃), thermocouple thermometer (K-type thermocouple, accuracy ±0.1℃), digital display timer;

[0087] Materials: Fresh pork tenderloin (10mm thick, simulating human soft tissue, placed in a 37℃ constant temperature incubator for 1 hour before use), physiological saline (simulating body fluid, 0.9% sodium chloride solution).

[0088] 1.2 Test Procedure

[0089] Three electrodes (example / comparative samples) were taken, and the coating surface was wiped with physiological saline. They were then placed in a constant temperature environment of 37℃ for 30 minutes to eliminate the influence of temperature gradients. Pork tenderloin was fixed on an insulated test bench, and 0.5 mL of physiological saline was added to the surface. The high-frequency electrosurgical unit was set to "electrocutting mode" with a power of 10W (the standard clinical electrocutting power). The infrared thermal imager lens was aimed at the contact area between the electrode and the tissue (image range 5mm × 5mm), and the thermocouple probe was placed close to the edge of the contact area (1mm from the electrode tip). Data acquisition software was connected simultaneously. The high-frequency electrosurgical unit was started, with the electrode perpendicularly contacting the surface of the pork tenderloin. Electrocuting was performed continuously for 30 seconds (typical cutting time for a single surgery), during which the highest temperature at the contact point was recorded in real time using the infrared thermal imager. Each sample was tested three times, with fresh pork tenderloin used after each test to ensure consistent testing conditions. The average value was taken to obtain the electrocutting temperature, as shown in Table 2.

[0090] 2. Evaluation of electrical cutting temperature stability:

[0091] Aging method: The electrode to be tested (example / comparative sample) was placed in wet sterilization at 121℃ for 5 min and dried at 50℃ for 6 h. After drying, fresh pork tenderloin was electrocutted for 30 seconds, rinsed with physiological saline, and repeated 500 times. The electrocutting temperature was measured again, and the data are shown in Table 2.

[0092] 3. Long-lasting antibacterial performance test:

[0093] Test strain: Staphylococcus aureus ATCC 25923, a common pathogen causing surgical infections;

[0094] The standard strain was inoculated onto nutrient agar medium and incubated at 37°C for 24 hours. Single colonies were then picked and inoculated onto nutrient broth medium, and cultured with shaking for 18 hours. The culture was then diluted with sterile physiological saline to a bacterial concentration of (1.0-5.0) × 10⁻⁶. 6 CFU / mL, ready for use; take the electrode to be tested (coating area ≥ 1 cm²). 2 After sterilization with ultraviolet light for 30 minutes, the substrate was placed in a sterile petri dish. 0.2 mL of bacterial suspension was added to the coating surface, and the substrate was incubated at 37°C for 24 hours. After incubation, 5 mL of 0.05% Tween 80 solution was added, and the substrate was eluted for 10 minutes. The eluent was serially diluted and spread onto nutrient agar plates, incubated at 37°C for 24 hours, and the colony count was recorded (denoted as A). For the blank control group, the above steps were repeated using the same electrode substrate (same area) without coating, and the colony count was recorded (denoted as B).

[0095] Calculate the immediate antibacterial rate: Antibacterial rate (%) = (1-A / B)×100, and the data is shown in Table 2;

[0096] Long-lasting antibacterial performance test: The electrode to be tested (example / comparative sample) was placed in wet sterilization at 121℃ for 5 min, dried at 50℃ for 6 h, and after drying, fresh pork tenderloin was electrocutted for 30 seconds, rinsed with physiological saline, and repeated 500 times. The immediate antibacterial rate was retested and the immediate antibacterial rate retention rate was calculated. The data are shown in Table 2.

[0097] Table 2

[0098] Initial electrical cutting temperature (°C) Electro-cutting temperature after aging (°C) Initial immediate antibacterial rate (%) Immediate antibacterial rate after aging (%) Example 1 34.0 34.5 99.5 98.5 Example 2 34.2 34.6 99.4 98.2 Example 3 34.1 34.4 99.3 98.6 Example 4 33.9 34.2 99.5 98.7 Comparative Example 1 34.3 35.1 98.5 59.1 Comparative Example 2 34.1 34.7 98.0 53.9 Comparative Example 3 34.2 34.6 99.0 69.3 Comparative Example 4 34.0 34.5 8.5 6.8 Comparative Example 5 39.2 43.3 99.2 95.2 Comparative Example 6 40.1 46.2 99.1 95.1

[0099] The electrocautery temperature of the examples remained stable in the initial state and after aging treatment, without significant fluctuations. The initial immediate antibacterial rate was high, and even after aging treatment, the antibacterial retention was good, demonstrating outstanding long-lasting antibacterial performance. In contrast, some comparative examples (such as those replaced with other types of antibacterial agents) showed acceptable initial immediate antibacterial rates, but after aging, the antibacterial effect declined significantly, indicating insufficient long-lasting efficacy. The comparative examples without added long-lasting antibacterial agents consistently exhibited low antibacterial rates, both initially and after aging. Furthermore, the comparative examples without added polytetrafluoroethylene powder or graphene had significantly higher initial electrocautery temperatures than the examples, and the electrocautery temperature further increased after aging, indicating weaker temperature control and stability compared to the examples.

[0100] Although embodiments of the invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A coating composition for a surgical electrode with an electrocautery temperature below 37°C, characterized in that, It is composed of the following components in parts by weight: 25-35 parts epoxy resin, 15-25 parts polyurethane resin, 5-10 parts graphene, 3-8 parts polytetrafluoroethylene powder, 2-5 parts silica nanoparticles, 1-3 parts silane coupling agent, 30-50 parts organic solvent, and 1-2 parts long-lasting antibacterial agent. The long-acting antibacterial agent has the structure shown in Formula 1: The chemical formula of Formula 1 is: ; In Formula 1, R1 is a substituent, and R1 is any one of hydrogen, methyl, ethyl, and chlorine.

2. The coating composition for a surgical electrode with an electrocautery temperature below 37°C as described in claim 1, characterized in that, The epoxy resin is a bisphenol A type liquid epoxy resin with an epoxy value of 0.48-0.54 eq / 100g.

3. The coating composition for a surgical electrode with an electrocautery temperature below 37°C as described in claim 1, characterized in that, The polyurethane resin is an aqueous polyurethane resin with a solid content of 33.5-35.5% and a viscosity of 500-1,000 mPa·s at 25℃.

4. The coating composition for a surgical electrode with an electrocautery temperature below 37°C as described in claim 1, characterized in that, The silane coupling agent is any one of KH550, KH560, and KH570.

5. The coating composition for a surgical electrode with an electrocautery temperature below 37°C as described in claim 1, characterized in that, The organic solvent is any one of tetrahydrofuran, N-ethylpyrrolidone, and toluene.

6. The coating composition for a surgical electrode with an electrocautery temperature below 37°C as described in claim 1, characterized in that, The long-acting antibacterial agent is any one of the compounds shown in the following structures: ； 。 7. A surgical electrode with a composite coating and an electrocautery temperature below 37°C, characterized in that, The surgical electrode includes an electrode substrate and a composite coating applied to its surface; The composite coating is prepared from a coating composition for a surgical electrode with an electrocautery temperature below 37°C as described in any one of claims 1-6; The electrode substrate is made of stainless steel or titanium alloy and is needle-shaped or ring-shaped.

8. The method for preparing a surgical electrode with a composite coating and an electrocautery temperature below 37°C as described in claim 7, characterized in that, Includes the following steps: S1: Dissolve the epoxy resin and polyurethane resin in an organic solvent and stir and mix at 40-60°C for 30-60 minutes to obtain a resin solution; S2: Add the graphene, polytetrafluoroethylene powder, silica nanoparticles, silane coupling agent and long-lasting antibacterial agent to the resin solution, and disperse it at 1000-2000 rpm for 60-120 minutes using a high-speed disperser to obtain a uniform coating slurry. S3: Apply the coating slurry to the surface of the electrode substrate after the blade has been sharpened. The coating thickness is 50-100μm. Curing treatment is carried out at 80-120℃ for 1-2 hours. The entire electrode surface is covered by the coating, with only the sharpened part of the electrode remaining exposed at the micron level. This results in a surgical electrode with a composite coating and an electric cutting temperature of less than 37℃.

9. A method for preparing a surgical electrode with a composite coating and an electrocautery temperature below 37°C as described in claim 8, characterized in that, S2 and S3 are carried out under a nitrogen atmosphere; The coating in S3 is applied by spraying or dipping, and after coating, it is left to stand for 10-20 minutes to allow it to level.

10. A method for preparing a surgical electrode with a composite coating and an electrocautery temperature below 37°C as described in claim 8, characterized in that, The curing process in S3 is divided into two stages: first, curing at 80°C for 30 minutes, and then curing at 120°C for 1 hour.

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