Unmanned biological safety detection square cabin with rapid modification function
By introducing dedicated large-size airtight doors, adjustable equipment fixing devices, and unmanned material transfer systems into the mobile testing cabin, the problems of equipment installation compatibility and process adaptability have been solved, enabling rapid modification and full-process automation, and improving the emergency testing response capability and biosafety.
Patent Information
- Application Number
- CN202511934224.4
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-12-20
- Publication Date
- 2026-02-24
AI Technical Summary
Existing mobile testing cabins lack compatibility in equipment installation, rapid sealing of the cabin, and adaptability to unmanned processes, resulting in low efficiency of modification and upgrades, interruption of automated processes, and difficulty in controlling biosafety risks. They are also unable to adapt to the rapid switching of testing functions in the context of a changing pandemic.
An unmanned material handling system consisting of dedicated large-size airtight doors, adjustable equipment fixing devices, track-type robots and fixed transfer robots, as well as an unmanned process integration system with modified equipment, is adopted to achieve rapid and safe entry and exit of large equipment, fully automated operation, and unmanned process self-adaptation.
It enables the safe and rapid entry and exit of large equipment, improves the efficiency and flexibility of equipment modification and upgrading, ensures the continuous closed-loop operation of the testing process, reduces the risk of human intervention and cross-contamination, and enhances the testing capabilities and biosafety protection level in emergency scenarios.
Smart Images

Figure CN121556720A_ABST
Abstract
Description
Technical Field
[0001] This invention relates to the field of emergency mobile detection equipment technology, and more specifically, to an unmanned biosafety detection container with rapid modification and upgrading capabilities. Background Technology
[0002] Biosafety testing modules play a crucial role in public health emergencies, port quarantine, and on-site emergency testing. Their primary function is to rapidly and safely detect pathogens, enabling early detection and isolation, and safeguarding public health, whether in mobile or fixed deployments. Existing mobile testing units are mostly based on modified standard shipping containers, integrating fixed testing equipment and semi-automated processes. However, facing the demands of pathogen mutation and varied testing tasks, it is often necessary to replace or add different models of testing equipment. This process involves multiple coupling stages, including the movement of large equipment into and out of the module and integration with existing unmanned systems. The operation is complex and time-consuming, posing a significant challenge to the rapid reconstruction and continuous operation of testing capabilities.
[0003] Currently, existing testing cabins mostly use pre-positioned bolt fixing or simple brackets for equipment installation, resulting in poor compatibility and difficulty in adapting to new equipment with diverse sizes and base layouts. This leads to customized modifications for each addition or upgrade, resulting in low efficiency. The airtightness, size, and strength of the cabin doors, which are crucial for equipment access, are often difficult to balance, affecting biosafety protection levels. More importantly, after adding new equipment, the original automated processes such as sample transport, reagent loading, and equipment operation are usually interrupted, requiring extensive manual reprogramming and debugging, failing to achieve plug-and-play functionality and severely limiting response speed. Furthermore, existing cabins lack the ability to automatically sense and adapt to the status of the modified equipment, logistics routes, and environmental parameters. System operation relies on human experience, leading to integration delays, process interruptions, and biosafety risks.
[0004] This demonstrates the urgent need for existing mobile testing modules to adapt to the rapidly changing testing functions and the continuous, fully unmanned operation required in the context of a rapidly evolving pandemic. Therefore, there is a pressing need for a testing module system that allows for rapid compatibility and installation of equipment, reliable airtight entry and exit, and intelligent integration of new equipment into existing unmanned processes. This would address issues such as low efficiency in retrofitting and automation interruptions in existing technologies. Summary of the Invention
[0005] In view of this, the present invention proposes an unmanned biosafety testing cabin with rapid modification and refit capabilities, aiming to solve the shortcomings of existing mobile testing cabins in terms of equipment installation compatibility, rapid cabin sealing and adaptive integration of unmanned processes, which lead to low modification and refit efficiency, interruption of automated processes and difficulty in biosafety risk control.
[0006] This invention proposes an unmanned biosafety testing container with rapid modification capabilities, comprising: The main body of the modular cabin is a closed structure based on the modification of a standard shipping container. Its interior is divided into multiple zones according to function, including equipment room, central control room, spare room, sample storage room, consumable storage and replacement room, biological laboratory work room, generator room and waste disposal room. The controllable flow of material and air is achieved between the zones through conveyor tracks, pass-through windows and buffer doors. Specialized large-size airtight doors are installed on the side walls of the biological laboratory work area. They adopt a double-opening structure and include a door frame, main door, auxiliary door, mechanical lock, hinges, limit devices, sealing strips, and internal foam filling structure. They are used for the safe entry and exit of large testing equipment and to maintain the airtightness of the cabin. An adjustable equipment fixing device is installed on the floor of the biological laboratory work area. It adopts a two-dimensional reconfigurable fixing matrix formed by bottom slide rail, upper slide rail and multiple sets of slider nuts to adapt to testing equipment of different sizes and different foot layouts, so as to realize the rapid positioning, fixing and disassembly of large equipment. An unmanned material handling system consisting of track-mounted robots, fixed transfer robots, and multiple conveyor tracks is used to automatically complete processes such as sample entry, consumable replenishment, sample transfer, inspection operations, and waste removal after new equipment is loaded, forming a closed loop of unmanned detection throughout the entire process. The system integrates newly installed testing equipment into unmanned testing processes.
[0007] Furthermore, the dedicated large-size airtight door adopts a multi-seal structure that meets the requirements of negative pressure laboratory levels, wherein: The door frame is welded from metal profiles into an integral frame, with reinforcing ribs on the inside to resist the deformation force generated by the negative pressure inside the cabin. The main door and the auxiliary door have a sandwich structure of composite skin and foam filling inside, and decorative strips are set on the outside to improve the sealing performance; The hinges are densely arranged, with at least three points on the upper part to resist the impact load when the equipment moves in and out. Limiting devices can restrict the opening angle of the door and prevent the door from colliding with the equipment; Ensure that the static and dynamic airtightness of the cabin can be maintained during frequent installation and removal of equipment.
[0008] Furthermore, the adjustable device fixing device is a multi-layer slide rail composite structure, which includes: The bottom slide rail, fixed to the bottom plate of the cabin, extends longitudinally along the cabin, and multiple bottom slide nuts are pre-installed in the slide groove; The upper slide rail can move along the bottom slide rail, and its end is connected to the bottom slider nut by bolts to realize the longitudinal adjustment of the upper and lower slide rails; The upper part of the upper slide rail is equipped with an upper slider nut that slides laterally, which can achieve precise alignment of the equipment's foot holes in the lateral direction; Combined with a constant torque fastening process, it can ensure that testing equipment of different weights and structural forms remains stable and without displacement during transportation vibration, operational impact and long-term operation; It achieves seamless compatibility with the hole spacing and foot shape of different testing equipment bases, and supports rapid positioning and disassembly of equipment.
[0009] Furthermore, the adjustable equipment fixing device's slide rail matrix covers the main floor area of the biological laboratory workspace, and achieves efficient support for modification and upgrade operations in the following manner: The slide rails adopt a modular splicing method, and the coverage area can be adjusted according to the scale of the equipment; The slide rail is made of high-strength corrosion-resistant alloy steel, and its surface is treated with a coating that resists corrosion in biological experimental environments. The slide rail structure ensures stability under environmental conditions such as negative pressure, temperature and humidity changes, and disinfection spraying. This allows the bottom of the modular shelter to function as a reconfigurable equipment installation platform, achieving sustained reliability under high-frequency modification.
[0010] Furthermore, the unmanned process integration system for the modification and upgrading equipment includes: The automatic device identification module can automatically identify new devices by reading device ID, model information, or connection protocol. The driver adaptation module automatically loads the control protocol of the specified device through the local device driver library; for devices without pre-installed drivers, it imports the new device driver package through an external data interface and completes the registration. The robot parameter learning module relies on the robot's end-effector vision recognition system to scan visual marks on new equipment and obtain the equipment's spatial posture, interface position, and operation port characteristics. The path planning module generates a new path for the coordinated work of the track-based robot and the stationary robot based on the spatial layout and operational requirements of the new equipment, and combines it with the motion library to form a new operating procedure. The closed-loop execution verification module performs full-link simulation of the communication link, material logistics path and complete detection process to verify whether the unmanned process has continuity and reliability.
[0011] Furthermore, the unmanned material handling system includes: The sample transfer robot and sample transfer window in the sample temporary storage room are used to complete sample entry, temporary storage and transfer to the core testing area; Consumables transfer robots in the consumables storage and replacement room are used for automatic consumables replenishment; Waste treatment tanks are used to automatically collect, autoclave, and discharge waste. The track-mounted robot runs on the working track in the biological laboratory and undertakes the operation tasks between the core testing equipment, including sample transfer, consumable loading, reaction initiation, and product transfer. To achieve unmanned operation of the entire testing process and ensure the continuous and stable automation of the process after the equipment is installed.
[0012] Furthermore, the system is integrated after the new equipment is installed through the following steps: Equipment entry and airtightness restoration: After the dedicated large-size airtight door is opened, the equipment is pushed in, and the negative pressure environment inside the cabin is automatically restored after the installation is completed. Equipment spatial information acquisition: The robot vision system automatically scans the spatial coordinates, posture, and interface layout of the equipment. Driver loading and parameter registration: The system loads the driver or imports a new driver package based on the device model to complete the registration, and then adds the device to the global device list. The robot operation program is generated by the system's automatic job planning algorithm, which generates operation steps based on the equipment type, including grasping actions, interface plugging actions, and pick-and-place actions. The entire process is verified by simulating the complete process of "sample entry, equipment processing, and result output" to verify the consistency of the process. It enables device connection without manual reprogramming.
[0013] Furthermore, the modular shelter is equipped with standardized power interfaces, network interfaces, and data communication protocols, including: It adopts a standard data interface based on Ethernet to achieve high-speed communication with the central control system; Set up a redundant power supply system to ensure the continuity of power supply to the added equipment during operation; Multiple environmental monitoring sensors, including temperature sensors, differential pressure sensors, and humidity sensors, are deployed in the core experimental area of the middle layer to dynamically monitor the environment inside the cabin. Data is uniformly aggregated to the central control equipment for real-time analysis, ensuring that the equipment can be immediately integrated into the environmental monitoring closed-loop system after installation.
[0014] Furthermore, the modular unit has the capability to quickly replace functional modules for different testing tasks, including but not limited to: Nucleic acid extraction and testing lines, rapid nucleic acid testing equipment, unmanned nucleic acid sequencers, pathogen screening equipment, high-throughput automated equipment, etc., can be quickly replaced through adjustable fixing devices, standardized data interfaces, and unmanned integrated systems; It can quickly reconfigure its functions based on the sudden outbreak, pathogen type, and differences in testing tasks, enabling the mobile testing facility to expand from conventional testing mode to high-throughput mode, sequencing mode, or rapid screening mode.
[0015] Furthermore, the mobile shelter possesses a complete biosafety environment protection system, including: The ventilation system and negative pressure control unit maintain the pressure gradient between the core experimental area and the outside, ensuring that aerosols do not leak out. Multiple buffer doors and pass-through windows ensure biosafety isolation during sample entry and exit. The disinfection system is used for terminal disinfection before equipment installation and environmental disinfection during process operation; The control system monitors and adjusts parameters such as temperature, pressure, air velocity, and filtration efficiency inside the cabin in real time. To ensure that the mobile shelter maintains a stable operating state that meets biosafety requirements even with frequent equipment modifications.
[0016] Compared with existing technologies, the advantages of this invention are as follows: By setting up a dedicated large-size airtight door and adopting multiple sealing and reinforcement structures, the safe and rapid entry and exit of large-scale testing equipment is achieved, and the negative pressure and airtightness of the chamber are reliably maintained during frequent operations, ensuring the biosafety level of the core experimental area. Secondly, by using a two-dimensional sliding rail matrix structure for the adjustable equipment fixing device, seamless compatibility and rapid positioning and fixing of testing equipment of different sizes and foot layouts are achieved, significantly improving the efficiency and flexibility of equipment modification and upgrading, and avoiding the time-consuming and compatibility problems of traditional customized installation. In addition, through an unmanned material transfer system composed of a track robot, a fixed robot, and a conveyor rail, the entire process from sample entry, consumable replenishment, testing operation to waste disposal is automated, ensuring the continuous closed-loop operation of the testing process after the installation of new equipment, and minimizing the risk of human intervention and cross-contamination. Simultaneously, by integrating the modified equipment into an unmanned process system, utilizing automatic identification, driver adaptation, visual learning, and path planning, new equipment is intelligently and rapidly embedded into existing unmanned processes, achieving "plug-and-play" functionality for the new equipment. This solves the problems of process interruption and response delays caused by the need for manual reprogramming and debugging in traditional methods. Finally, while ensuring rapid equipment reconfiguration and process automation, the entire system continuously maintains a stable operating state that meets biosafety requirements through integrated environmental monitoring, negative pressure control, and disinfection systems. This invention significantly improves the mobile testing cabin's rapid response capability to changing tasks, its functional reconfiguration efficiency, and the reliability of fully unmanned operation, contributing to enhanced continuous testing support and biosafety protection levels in emergency scenarios. Attached Figure Description
[0017] Various other advantages and benefits will become apparent to those skilled in the art upon reading the following detailed description of preferred embodiments. The accompanying drawings are for illustrative purposes only and are not intended to limit the invention. Furthermore, the same reference numerals denote the same parts throughout the drawings. In the drawings: Figure 1 This is a schematic diagram of the equipment layout of an unmanned biosafety testing cabin with rapid modification capabilities, provided as an embodiment of the present invention. Figure 2 This is a schematic diagram of the external structure of a large-size airtight door for an unmanned biosafety testing cabin with rapid modification capabilities, provided in an embodiment of the present invention. Figure 3 This invention provides a schematic diagram of the internal structure of a large-size airtight door for an unmanned biosafety testing cabin with rapid modification capabilities, as shown in this embodiment of the invention. Figure 4 This is a schematic diagram of the bottom slide rail structure of an adjustable equipment fixing device for an unmanned biosafety testing cabin with rapid modification and upgrading capabilities, provided in an embodiment of the present invention. Figure 5 This is a schematic diagram of the upper slide rail structure of an adjustable equipment fixing device for an unmanned biosafety testing container with rapid modification capabilities, provided as an embodiment of the present invention.
[0018] The following are included: 110. Equipment Room; 111. Airtight Door to Equipment Room; 120. Central Control Room; 121. Airtight Door to Central Control Room; 130. Spare Room; 140. Sample Storage Room; 141. Fixed Sample Transfer Robot; 142. Sample Transfer Window; 150. Consumables Storage and Replacement Room; 151. Consumables Transfer Robot; 152. Airtight Door to Consumables Storage and Replacement Room; 160. Biological Laboratory Workspace; 170. Generator Room; 180. Waste Disposal Room; 181. Waste Disposal Pool; 210. Dedicated Large-Size Airtight Door 211. Door frame; 212. Main door; 213. Secondary door; 214. Mechanical lock; 215. Hinge; 216. Limiting device; 217. Sealing strip; 218. Reinforcing rib; 310. Adjustable equipment fixing device; 311. Bottom slide rail; 312. Slide groove; 313. Bottom slider nut; 314. Upper slide rail; 315. Bolt; 316. Upper slider nut; 410. Track-mounted robot; 420. Fixed transfer robot; 430. Conveyor track; 510. Transfer window; 610. Buffer door. Detailed Implementation
[0019] Exemplary embodiments of the present disclosure will now be described in more detail with reference to the accompanying drawings. While exemplary embodiments of the present disclosure are shown in the drawings, it should be understood that the present disclosure may be implemented in various forms and should not be limited to the embodiments set forth herein. Rather, these embodiments are provided to enable a more thorough understanding of the present disclosure and to fully convey the scope of the disclosure to those skilled in the art. It should be noted that, unless otherwise specified, embodiments and features in the embodiments of the present invention can be combined with each other. The present invention will now be described in detail with reference to the accompanying drawings and embodiments.
[0020] Figures 1-5 As shown in some embodiments of this application, this embodiment provides an unmanned biosafety testing cabin with rapid modification and upgrading capabilities, including: a cabin body, a dedicated large-size airtight door, an adjustable equipment fixing device, an unmanned material transfer system composed of a track-type robot, a fixed transfer robot and multiple transfer tracks, and an unmanned process integration system for modification and upgrading equipment.
[0021] Specifically, the main body of the modular unit is a sealed structure modified from a standard shipping container. Its interior is meticulously divided into several strictly defined zones based on function, including equipment rooms, a central control room, a spare room, a sample storage room, a consumables storage and replacement room, a biological laboratory workroom, a generator room, and a waste disposal room. These zones are not isolated but are connected by a pre-set transmission network, airlocked transfer windows, and multiple buffer doors. This ensures the controllable and directional flow of materials (samples, consumables, and waste) and airflow (maintaining a pressure gradient), fundamentally eliminating the risk of cross-contamination and aerosol leakage. A dedicated large-size airtight door is installed on the side wall of the biosafety laboratory workspace. It features a double-opening structure and integrates a high-strength door frame, main and auxiliary door panels, multiple mechanical locks, encrypted hinges, intelligent limit devices, multiple sealing strips, and an internal thermal and sound insulation foam structure. Its core mission is to ensure the safe and smooth entry and exit of various large and heavy testing equipment, and to quickly and reliably restore and maintain the airtightness of the chamber, especially the core negative pressure experimental area, after the equipment is in place, meeting the static and dynamic sealing requirements of a high-level biosafety laboratory. An adjustable equipment fixing device is located on the floor of the biosafety laboratory workspace. It is not a traditional pre-embedded bolt point, but an innovative two-dimensional reconfigurable fixing matrix. This device consists of a bottom fixed slide rail, an upper movable slide rail, and numerous embedded sliding nuts, forming a checkerboard-style installation platform covering the main equipment installation area. Regardless of the size of the newly added testing equipment or the variations in the base hole spacing and foot shape, longitudinal coarse adjustment can be performed by sliding the upper slide rail, followed by lateral fine adjustment by moving the upper slider nut. This allows for quick and precise alignment of the equipment's feet. Finally, tightening with a torque-controlled tool completes the stable installation of the equipment, completely eliminating the inefficient method of customizing bases for each type of equipment. The unmanned material handling system consists of multiple track-mounted robots, fixed transfer robots deployed between various functions, and a crisscrossing conveyor network. After new equipment is loaded, this system can automatically adapt to new spatial layouts and operational requirements, seamlessly taking over the entire process from sample entry, temporary storage, and transmission, to automatic consumable replenishment, loading and unloading of testing equipment, reaction start-up and monitoring, and finally to waste collection, sterilization, and disposal. This forms a complete, closed, and unmanned testing loop, greatly ensuring the safety of operators and the standardization of the testing process. The core function of the unmanned process integration system for retrofitted equipment is to intelligently and automatically integrate newly added testing equipment of various models into the existing unmanned testing process. This system achieves "plug-and-play" functionality for new equipment by automatically identifying device identity, intelligently loading or adapting driver protocols, utilizing robot vision to learn device spatial posture and operation interfaces, dynamically planning robot collaborative operation paths, and finally conducting full-link simulation verification. This allows the modular unit to complete functional reconstruction and be put into fully automated operation within hours, enabling it to cope with sudden detection tasks.
[0022] Understandably, through the aforementioned modular, intelligent, and flexible integrated design, this embodiment achieves a comprehensive upgrade of the biosafety testing cabin from its physical structure to its control logic. At the cabin's main body level, the modification of standard shipping containers ensures convenient mobile deployment and robust basic structure. The internal scientific zoning and controllable flow channel design lay the physical foundation for biosafety. Dedicated large-size airtight doors resolve the long-standing contradiction between the entry and exit of large equipment and high-level biosafety protection; their reinforced structure and multi-seal design ensure both "large opening" and "high airtightness." Adjustable equipment fixing devices transform the cabin floor into a universal and flexible installation interface, fundamentally improving the compatibility and efficiency of equipment modification and upgrades, serving as the cornerstone for rapid functional reconfiguration of the cabin. The unmanned material transfer system completely liberates manpower from high-risk, repetitive laboratory operations, not only improving efficiency and consistency but also being crucial for maintaining a biosafety environment. The unmanned process integration system for equipment modification and upgrades, serving as the top-level intelligent control layer, deeply couples hardware (new equipment), infrastructure (fixed devices, transportation systems), and software processes. Through a series of automated and intelligent steps, it eliminates the most time-consuming "manual integration and debugging" step in the traditional modification and upgrade process, giving the mobile testing facility a rapid adaptability and expansion capability similar to the "hot-swappable" peripherals of a computer. These five interconnected components together constitute an advanced mobile biosafety testing platform capable of responding to sudden outbreaks, rapidly switching testing modes, and continuously and stably conducting unmanned operations.
[0023] In a specific embodiment of this application, the above system is implemented as follows: An unmanned biosafety testing cabin with rapid modification capabilities is constructed by modifying a 40-foot standard high-cube container. The exterior is insulated and reinforced, while the interior is decorated with lightweight, corrosion-resistant, and easy-to-clean metal composite panels. An equipment room 110 is located at one end of the cabin and is used to house public equipment such as UPS and air conditioning units. A central control room 120 is adjacent to the equipment room and houses a central control computer, an environmental monitoring display screen, and communication equipment. A spare room 130 can be converted into a changing room or used to store spare parts as needed. A sample storage room 140 is equipped with a double-door high-pressure sterilization transfer window 510 connecting to the outside. Inside, it is equipped with a fixed sample transfer robot 141 and a sample transfer window 142 for scanning, classifying, and temporarily storing input samples. A consumables storage and replacement room 150 is equipped with large shelves, a consumables transfer robot 151, and an airtight door 152, enabling automatic identification and replenishment of reagents and consumable boxes. The biological laboratory workspace 160 is the core area. Most of the floor is covered with adjustable equipment mounting devices 310 made of high-strength alloy steel, and it also features I-beam tracks for the track-mounted robot 410. Dedicated large-size airtight doors 210 are located on the side walls. The generator room 170 provides independent power to the container. The waste disposal room 180 contains a waste disposal pool 181 with a built-in autoclave for automatic waste collection and sterilization. All areas are separated by buffer doors 610. The core experimental area 160 maintains a relative negative pressure, which is monitored in real time by differential pressure sensors and fed back to the central control system for adjustment.
[0024] The specific structure of the special large-size airtight door 210 is as follows: The door frame 211 is welded into an integral frame from high-strength aluminum alloy profiles, with "well"-shaped reinforcing ribs 218 welded on the inner side to resist the inward deformation force generated by the negative pressure of -30Pa to -50Pa inside the cabin. The main door 212 and the auxiliary door 213 adopt a sandwich structure of aviation aluminum plate skin and flame-retardant polyurethane foam filling, which is lightweight and high-strength. The edge of the door leaf is inlaid with three different types of sealing strips 217: the outermost is a rubber scraper strip for initial dust removal; the middle is an inflatable sealing strip that automatically inflates and expands after the door is closed to ensure a tight fit; the innermost is a magnetic sealing strip that uses magnetic force to enhance the sealing effect. The hinges 215 are heavy-duty load-bearing hinges, and at least three sets are densely arranged on the upper part of the door leaf to distribute the impact load that may be generated on the door body when equipment enters and exits. The limiting device 216 is a hydraulic damping limiter, which can stabilize the door opening angle at 90° or 120° and prevent the door from colliding with equipment or bulkheads due to wind or misoperation. The mechanical lock 214 uses a multi-point linkage latch to ensure that the door is tightly closed.
[0025] The adjustable equipment fixing device 310 is implemented as follows: First, multiple bottom slide rails 311 are laid parallel to each other along the longitudinal direction of the container on the steel bottom plate of the hull. Each bottom slide rail 311 has a continuous groove 312, and numerous bottom sliding block nuts 313 that can slide along the groove are pre-installed in the groove. The cross-section of the upper slide rail 314 is similar to that of the bottom slide rail, but the length is shorter. During installation, the upper slide rail 314 is laid across the two parallel bottom slide rails 311, and bolts 315 are passed through the mounting holes at the ends of the upper slide rails to connect with the bottom sliding block nuts 313 that have been pre-slid to the appropriate position in the groove of the lower slide rail and tightened, thereby realizing the fixation and adjustment of the upper slide rail in the longitudinal position. The upper surface of each upper slide rail 314 also has a groove and is equipped with an upper sliding block nut 316 that can slide laterally on it. When securing a new piece of equipment, first adjust the spacing of the upper slide rails 314 longitudinally to the approximate position based on the size of the equipment base and the position of the foot pads, and then lock them. Next, slide the slider nuts 316 on each upper slide rail 314 laterally to precisely align them with the mounting holes on the equipment's base. Finally, place the equipment in position and use dedicated hexagonal socket head cap screws to pass through the base holes and tighten them to the upper slider nuts 316. All bolts are tightened using a torque-controlled electric wrench to ensure consistent preload and compliance with the equipment's load-bearing requirements. The slide rail surfaces are galvanized and coated with Teflon, providing excellent corrosion resistance, wear resistance, and low friction properties to withstand the disinfectant spraying environment commonly found in biological laboratories.
[0026] The core of the unmanned material handling system is the track-mounted robot 410. The robot's end effector is a quick-change device that can automatically grasp different end effectors according to task requirements, such as mechanical grippers, micro-pipettes, plate grippers, and barcode scanners. Fixed transfer robots 420 are mainly deployed in the sample storage room 140 and the consumables storage and replacement room 150, and are either ground-mobile AGVs or robotic arms. The conveyor tracks 430 network connect all the main functional areas, enabling the directional and efficient flow of materials.
[0027] The integrated unmanned process system for retrofitted equipment is a combination of software and hardware. Its operation relies on a server located in the central control room (120) and controllers deployed on various robots and equipment. The system includes the following core modules: Automatic Equipment Identification Module: After a new device enters the cabin through the airtight door and is physically secured and connected to the power supply and network cable, this module automatically identifies the new device by scanning the device's barcode / RFID or actively reading the model and serial number information broadcast by the device via Ethernet / IPC protocol.
[0028] Driver adaptation module: The system maintains a local device driver library. Upon successful identification, this module automatically searches the library for matching device control drivers (such as Modbus TCP, OPC UA, specific APIs, etc.) and loads them. For new brands or models of devices not pre-installed in the library, maintenance personnel can import standard driver packages provided by the device manufacturer (following the system-defined driver encapsulation specifications) via the external USB interface provided in the cabin. The system automatically completes driver parsing, registration, and integration.
[0029] Robot Parameter Learning Module: This module controls the tracked robot 410 to activate its end-effector's vision recognition system, typically a high-precision industrial camera and light source. As the robot moves to the new equipment, it scans pre-attached or inherent visual markers on the equipment's surface, such as positioning blocks of specific shapes. Through visual algorithms, the system accurately calculates the new equipment's three-dimensional spatial coordinates and tilt posture within the global coordinate system of the control room, and identifies the locations of key operating interfaces, such as sample loading door handles, reagent slot openings, touchscreen locations, and switch buttons, recording the coordinates of these feature points into the system database.
[0030] Path planning module: Based on the spatial coordinates, attitude, and identified operation interface information of the new equipment, as well as the standardized operation process template for this type of testing equipment (such as the "nucleic acid extractor" template including: opening the hatch, placing the sample plate, closing the hatch, starting the program, etc.), this module automatically performs collision detection and motion planning. It plans the optimal spatial path for the track-mounted robot 410 to move from the standby position to various operation points of the equipment, and plans specific action sequences (such as grasping, pressing, rotating, inserting and removing, etc.) for the robot's end effector. At the same time, it coordinates the start and stop sequence of the fixed transfer robot, generating a new, executable collaborative operation program.
[0031] Closed-loop execution verification module: Before formal production deployment, the system enters "drill mode." In this mode, the system simulates a complete testing process without actually consuming samples and reagents: starting with simulated sample input, triggering the robot to execute newly generated operating procedures, virtually driving new equipment to perform each step, simulating product output and transfer to the next stage, until waste disposal. This module monitors the entire process to ensure communication links are smooth, robot movements are precise and collision-free, equipment status feedback is normal, and process sequence is consistent. Any anomalies in any stage will generate a detailed report, guiding engineers to make fine-tuning adjustments until the entire simulation verification is successful.
[0032] Understandably, the unmanned process integration system for retrofitted equipment achieves collaborative work among its internal modules through intelligent, closed-loop control of equipment access and process fusion, forming a complete intelligent integrated link from perception and decision-making to verification. The automatic equipment identification module can promptly acquire the identity information of new equipment, enabling rapid identification and registration. The drive adaptation module is responsible for loading and adapting the equipment control protocol, ensuring normal communication and control between the system and the new equipment. The robot parameter learning module uses visual recognition technology to acquire the spatial pose, interface layout, and operational characteristics of the new equipment, providing the system with accurate equipment spatial information. The path planning module generates the robot's collaborative operation path and action sequence based on equipment information and operational requirements, forming an executable operation program. The closed-loop execution verification module verifies the coherence and reliability of communication, logistics, and operational processes through full-link process simulation, ensuring the stable operation of the integrated system. This mechanism provides a fast and reliable channel for new equipment from physical access to full integration into the unmanned detection process, significantly improving the automation level, integration efficiency, and overall system reliability of the modular unit during functional reconfiguration.
[0033] Specifically, the system is integrated after the new equipment is installed through the following steps: Step S1, Equipment Entry and Airtightness Restoration: The operator places the new testing equipment on a specially designed wheeled transport platform from the outside. The dedicated large-size airtight door 210 is opened, and the equipment is pushed into the designated area within the biosafety laboratory workspace 160. After closing the airtight door, the door control system automatically activates, the mechanical lock 214 engages, and the inflatable sealing strip begins pressurization. The environmental monitoring system monitors the pressure inside the chamber in real time, and the ventilation system automatically adjusts, typically restoring and stabilizing the negative pressure in the core experimental area to the set value (e.g., -40 Pa) within 3 to 5 minutes, ensuring the priority reconstruction of the biosafety barrier.
[0034] Step S2, Equipment Spatial Information Acquisition: The central control system issues a command, and the track-mounted robot 410 moves from the standby position to the new equipment position. The robot's end effector vision recognition system is activated, taking multi-angle photos of multiple pre-set positioning marks on the equipment surface. The vision processing algorithm calculates the precise six-degree-of-freedom pose of the equipment in the global coordinate system of the container through triangulation and coordinate transformation. Simultaneously, the system guides the robot to perform contour recognition and coordinate calibration of key features on the front of the equipment, such as the operation panel, sample compartment door, reagent tank, and output port. All acquired spatial information is automatically stored in the equipment information database.
[0035] Step S3, Driver Loading and Parameter Registration: The device auto-identification module uploads the identified device model information to the driver adaptation module. This module searches the local driver library; if a matching driver is found, it automatically loads it and establishes a communication connection with the new device. If it is a new model, the system prompts the operator to insert a USB flash drive containing the standard driver package, automatically completing driver installation and registration. After communication is established, the system sends a self-test command to the new device to obtain the device status, supported function list, and initial parameters, and officially registers the device in the global device management list of the mobile cabin, assigning it a unique logical ID.
[0036] Step S4: Robot operation program generation: The path planning module is activated. It first calls the "standard operating procedure template" for this type of device (e.g., for a "high-throughput fluorescence PCR instrument," the template might include steps such as: opening the hot cap, scanning the code to identify the reaction plate, placing the reaction plate into the well, closing the hot cap, starting the amplification program, and removing the reaction plate after completion). Then, the module binds the abstract steps in the template (such as "placing the reaction plate") with the specific spatial coordinates acquired in step S2 (such as the precise three-dimensional coordinates of the reaction plate slot). Next, using kinematic algorithms and collision detection models, it plans the optimal smooth path for the track-mounted robot 410 from grasping the reaction plate to moving to the device slot, performing the placement action, and exiting, and generates a robot control program containing the timing of each joint angle, velocity, and acceleration. Simultaneously, the program also integrates interactive commands with the device driver (such as sending the "open cap" command).
[0037] Step S5, Full-Process Verification: The closed-loop execution verification module activates "Shadow Mode" or "Dry Operation Mode." The system uses a virtual sample board or a real empty board to start the process. The track-mounted robot 410 strictly follows the newly generated control program to execute actions, but actuators such as pipettes do not actually dispense liquid. The new equipment receives simulated instructions sent by the system and provides feedback with virtual status signals. The system monitors the entire process: whether the robot accurately reaches each path point; whether the equipment responds correctly to instructions (e.g., whether the door responds "open"); whether the material flow logic is correct; and whether the overall process timeout meets expectations. Any communication timeout, action failure, or logical error at any step will pause the verification and generate a detailed diagnostic log. Engineers can fine-tune the program or calibrate the equipment parameters based on the logs, and then re-verify until the entire simulated process of "sample entry - equipment processing - result output" is executed completely smoothly and reliably.
[0038] Step S6, Production Deployment: After the entire process verification is passed, the status of the new equipment changes to "Ready" on the central control interface. Operators only need to select the test item combination that includes the new equipment in the central control software, start the task, and the modular testing facility can begin fully automated and unmanned formal testing operations. This achieves intelligent integration of the entire process from the new equipment entering the facility to production, eliminating the need for manual complex coordinate teaching, logic programming, and integration debugging.
[0039] Understandably, the standardized six-step integration process described above achieves the proceduralization, automation, and verification of the modification and upgrade process. Step S1 ensures the bottom line of biosafety, minimizing the risks associated with introducing equipment. Steps S2 and S3 complete the "identity registration" and "communication" capabilities of the new equipment, forming the foundation for intelligent integration. Step S4 is the core "capability generation" step, transforming the physical existence of the equipment into automated capabilities that the system can understand and execute. Step S5 is the crucial "safety verification" step, similar to pre-release software testing, fully exposing and resolving integration issues in a virtual environment, ensuring stability and reliability during formal operation, and avoiding sample loss, reagent waste, or even safety incidents caused by integration failures in real testing tasks. Finally, step S6 achieves "seamless switching," where the user only perceives an additional option in the testing menu, while the complex integration work behind the scenes is automatically completed by the system. These six steps form an efficient, reliable, and safe closed loop, turning rapid modification and upgrades from a concept into reality.
[0040] Specifically, the path planning module in the integrated system for unmanned processes of the modified equipment includes an intelligent planning and optimization unit. This unit performs multi-level decision-making and optimization when generating robot operating procedures based on new equipment information: Layer 1: Basic Path Generation and Collision Avoidance. The unit calls upon the global 3D digital map of the control module, loading the model of the new equipment and its operating interface coordinates into the map. Based on Rapid Expanding Random Tree (RRT), a collision-free path is searched in the robot's configuration space (C-Space) from the starting point (e.g., the loading point) to each operating point (e.g., equipment door, reagent tank). This stage ensures the physical feasibility of the path.
[0041] The second layer: Multi-robot collaboration and timing optimization. When the task involves the collaboration between the track-mounted robot 410 and the fixed transfer robot 420 or the conveyor track 430, this unit performs spatiotemporal joint planning. It calculates the earliest start time and latest finish time of each action, considers the mutual exclusion of resources, resolves potential conflicts, and generates a collaborative Gantt chart with timing constraints to ensure a smooth process without waiting.
[0042] The third layer: Energy consumption and efficiency balance optimization. When multiple feasible paths exist, the unit establishes an evaluation function with variables including total path length, total robot joint motion, estimated execution time, and whether it traverses high-speed / low-speed regions. An optimization algorithm (such as a greedy algorithm or a genetic algorithm) selects the path with the highest overall score. For example, for non-urgent consumable replenishment tasks, a smoother, lower-energy-consumption path might be chosen; for critical sample transfer tasks, the shortest path is prioritized.
[0043] The fourth layer: Dynamic replanning based on real-time status. This unit continuously monitors the system status. If, during verification or actual operation, a critical sensor (such as a door status sensor) reports an anomaly, or the system detects an unmodeled temporary obstacle (via the robot's anti-collision sensor), the unit can immediately interrupt the current path and, based on the updated environmental information, quickly replan a new path from the current pose to the target (or safety point) online.
[0044] Understandably, the four-layer planning architecture of the intelligent planning and optimization unit enables the robot's operating program to evolve from "collision-free" to "optimal collaboration" and then to "dynamic adaptation." The first layer addresses the fundamental safety issue of "whether the path can be traversed." The second layer addresses the multi-agent collaboration issue of "how to coordinate effectively," weaving multiple automated units into an orderly "symphony orchestra." The third layer addresses the optimization issue of "how to traverse better," achieving a balance between efficiency, energy consumption, and equipment wear, reflecting the system's economy and intelligence. The fourth layer endows the system with the ability to "respond to emergencies" in the face of uncertainty, enabling it to handle unexpected situations and ensuring the continuity and reliability of the entire unmanned process. This unit is the "intelligent core" of the path planning module, transforming a simple sequence of coordinate points into a safe, efficient, and flexible automated operation strategy.
[0045] In a specific embodiment of this application, the above steps are implemented in the following scenario: Suppose it is necessary to install and integrate a newly arrived "fully automated nucleic acid extraction and purification instrument". The device has dimensions of 1200mm × 800mm × 900mm and the base has 4 M12 mounting holes.
[0046] 1. Entry and Securing: The equipment enters through the airtight door 210 and is roughly pushed to the central area of the biological laboratory workspace 160. Based on the equipment base dimensions, the engineer selects two bottom slide rails 311 with a spacing of approximately 700mm. Two upper slide rails 314 are connected to the bottom slide rail nuts 313 using bolts 315, securing them at this spacing. Then, the slide rail nuts 316 on the upper slide rails 314 are slid to adjust their lateral spacing to match the distance between the equipment's base holes. The equipment is then in place and secured with bolts. The equipment's power supply and network cable are connected.
[0047] 2. Identification and Driver: After the device powers on, its network port automatically broadcasts a message containing the information "Model-NXP-9600, SN:202503001". The device automatic identification module captures this information. The driver adaptation module finds the driver for the "NXP-9600" model (based on HTTPS RESTful API) in the library and loads it automatically. The system establishes stable communication with the new device through IP address allocation and obtains its supported instruction set.
[0048] 3. Visual Learning: The central control system sends commands. The track-mounted robot 410 moves above the equipment. Four ArUco tags are affixed to the front of the equipment. The robot's vision system takes pictures, identifies the tags, and, based on the known fixed positional relationship of the tags on the equipment body, accurately calculates the equipment's position in the container coordinate system as (X=2500mm, Y=1800mm, Z=0mm (ground), horizontally placed). Simultaneously, the system guides the robot to identify and record the coordinates of the center point of the sample compartment door handle, the reagent tank inlet, and the center coordinates of the touchscreen.
[0049] 4. Program Generation and Verification: The path planning module calls the standard template for the "Nucleic Acid Extractor". The template step "Open Sample Chamber Door" is bound to the recorded handle-hand coordinates. The module plans the robot path as follows: Grab the appropriate pipette tip from the "Pipette Replacement Station" - move to the "Deep Well Plate Temporary Storage Position" to grab the empty deep well plate - move to the top of the reagent tank of the nucleic acid extractor to perform the liquid addition action (virtual) - move to the door handle coordinates, the end effector switches to "gripper", and performs the "grab-pull down" action to simulate opening the door - place the deep well plate into the designated position inside the device - simulate closing the door - move to the safe position.
[0050] 5. Production Launch: Validation Successful. The "NXP-9600 Nucleic Acid Extractor" appears in the device list in the central control software. Users create a "Sample Extraction" workflow, linking it with sample entry and subsequent PCR testing. After startup, real samples are transported, and the robot performs actual liquid addition, door opening, and plate placement operations. The equipment operates automatically, and the extracted nucleic acid is retrieved by the robot and transferred to the next stage; the entire process is completed automatically.
[0051] The above specific examples fully demonstrate the entire process from the entry of an unfamiliar device into the cabin to its integration into a reliable link in the unmanned testing production line. This reflects the powerful rapid reconfiguration and intelligent integration capabilities of the cabin system described in this invention.
[0052] Specifically, when dealing with the new layout after modification, the unmanned material handling system's system coordination and control unit performs dynamic task scheduling and resource allocation: Task Analysis and Decomposition: When the central control system issues a new testing task order (e.g., "SARS-CoV-2 nucleic acid testing of 100 pharyngeal swab samples"), this unit first analyzes the task. The task is decomposed into a series of atomic operations: sample tube scanning, sample plate aliquoting, nucleic acid extraction, PCR system preparation, PCR amplification, and result analysis. Each atomic operation is mapped to specific physical equipment (newly added extraction instrument, existing PCR instrument, etc.) and logistical requirements (what consumables are needed, and where the products are shipped).
[0053] Resource status monitoring and scheduling: This unit monitors the status of all resources in real time: the current position and power of the track-mounted robot 410; the busy / idle status of the fixed transfer robot 420; the material occupancy status on each section of the conveyor track 430; and the current status of each piece of equipment, including new equipment.
[0054] Dynamic path allocation and conflict resolution: Based on task requirements and real-time resource status, this unit allocates a suitable robot to each atomic operation and plans its movement path. For example, when there are two tasks simultaneously, "replenishing consumables to the extractor" and "retrieving results from the PCR instrument," if the tracked robot resources are scarce, the unit may decide: the consumable replenishment task has lower priority and is executed by a fixed AGV via a ground path; while the task of retrieving PCR results is urgent and its path intersects with the flow of critical samples, so it is executed by a tracked robot. To avoid conflicts caused by path intersections, the unit introduces virtual traffic lights and reservation mechanisms, such as allowing a robot to reserve a specific section of track for a certain time period or adjusting its speed, to prevent deadlocks and collisions.
[0055] Anomaly Handling and Recovery: This unit continuously receives anomaly reports from underlying sensors and various devices. For example, if the consumables transport robot 151 reports "consumables box stuck," the unit will immediately mark the robot as "malfunctioning." It will reassess the current task, potentially rescheduling subsequent consumables needs to an alternative replenishment path, or sending an alert to the central control system requesting manual intervention. After the anomaly is resolved, the unit can automatically restore the affected workflow or provide a recovery plan for operator confirmation.
[0056] Understandably, through intelligent scheduling of the system coordination control unit, the unmanned material handling system is upgraded from a static, fixed-programmable automated system to a dynamic, adaptable intelligent logistics network. Task parsing and decomposition translate user requirements into machine-executable language. Resource status monitoring provides a "real-time situation map" for scheduling decisions. Dynamic path allocation and conflict resolution ensure optimal utilization of limited robot and transport network resources in high-concurrency, multi-tasking scenarios, ensuring smooth and unobstructed processes—key to achieving high-throughput detection. Anomaly handling and recovery mechanisms endow the system with strong fault tolerance and resilience; when a local failure occurs, the system does not completely collapse but can quickly respond, adjust strategies, degrade operations, or request assistance, maximizing the continuity of detection tasks. This unit is the command center ensuring that, after modification, both new and old equipment and robot logistics can operate efficiently, collaboratively, and stably.
[0057] In summary, this embodiment, through the detailed implementation methods described above, elucidates the overall structure, core component working principle, and intelligent integration process of an unmanned biosafety testing cabin with rapid modification and upgrade capabilities. The cabin's main body provides a standard and safe physical framework; a dedicated large-size airtight door resolves the conflict between equipment entry / exit and biosafety; adjustable equipment fixing devices provide unlimited equipment compatibility on the ground; the unmanned material transfer system achieves fully automated operation; and the unmanned process integration system for modification and upgrade equipment, particularly its built-in intelligent planning and optimization unit and system coordination and control unit, deeply integrates the aforementioned hardware modules through highly intelligent algorithms and closed-loop control logic, achieving rapid, automatic, and reliable integration of new equipment. This allows the cabin to flexibly and quickly replace core testing modules according to the development of the epidemic and technological advancements, such as switching from ordinary PCR to high-throughput sequencing, reconstructing testing capabilities in a very short time, and immediately putting it into fully automated, unmanned, and high-safety continuous operation, providing a powerful, flexible, and reliable mobile testing solution for responding to public health emergencies.
[0058] The above scenarios are merely preferred embodiments of the present invention and are not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present invention should be included within the protection scope of the present invention.
[0059] Those skilled in the art will understand that embodiments of this application can be provided as methods, systems, or computer program goods. Therefore, this application can take the form of a completely hardware embodiment, a completely software embodiment, or an embodiment combining software and hardware aspects. Furthermore, this application can take the form of a computer program goods embodied on one or more computer-usable storage media (including, but not limited to, disk storage, CD-ROM, optical storage, etc.) containing computer-usable program code.
[0060] This application is described with reference to flowchart illustrations and / or block diagrams of methods, apparatus (systems), and computer program goods according to embodiments of this application. It will be understood that each block of the flowchart illustrations and / or block diagrams, and combinations of blocks in the flowchart illustrations and / or block diagrams, can be implemented by computer program instructions. These computer program instructions can be provided to a processor of a general-purpose computer, special-purpose computer, embedded processor, or other programmable data processing apparatus to produce a machine, such that the instructions, which execute via the processor of the computer or other programmable data processing apparatus, generate instructions for implementing the flowchart... Figure 1 One or more processes and / or boxes Figure 1 A device that provides the functions specified in one or more boxes.
[0061] These computer program instructions may also be stored in a computer-readable storage medium that can direct a computer or other programmable data processing device to function in a particular manner, such that the instructions stored in the computer-readable storage medium produce an article of manufacture including instruction means, which are implemented in a process Figure 1 One or more processes and / or boxes Figure 1 The function specified in one or more boxes.
[0062] These computer program instructions may also be loaded onto a computer or other programmable data processing equipment to cause a series of operational steps to be performed on the computer or other programmable equipment to produce a computer-implemented process, thereby providing instructions that execute on the computer or other programmable equipment for implementing the process. Figure 1 One or more processes and / or boxes Figure 1 The steps of the function specified in one or more boxes.
[0063] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention and not to limit it. Although the present invention has been described in detail with reference to the above embodiments, those skilled in the art should understand that modifications or equivalent substitutions can still be made to the specific implementation of the present invention. Any modifications or equivalent substitutions that do not depart from the spirit and scope of the present invention should be covered within the scope of protection of the claims of the present invention.
Claims
1. An unmanned biosafety testing container with rapid modification capabilities, characterized in that, include: The main body of the modular cabin is a closed structure based on the modification of a standard shipping container. Its interior is divided into multiple zones according to function, including equipment room, central control room, spare room, sample storage room, consumable storage and replacement room, biological laboratory work room, generator room and waste disposal room. The controllable flow of material and air is achieved between the zones through conveyor tracks, pass-through windows and buffer doors. A dedicated large-size airtight door is installed on the side wall of the biological laboratory work area. It adopts a double-opening structure. The door body includes a door frame, main door, auxiliary door, mechanical lock, hinges, limit device, sealing strip and internal foam filling structure. It is used for the safe entry and exit of testing equipment and the maintenance of the airtightness of the chamber. An adjustable equipment fixing device is installed on the floor of the biological laboratory work area. It adopts a two-dimensional reconfigurable fixing matrix formed by bottom slide rail, upper slide rail and multiple sets of slider nuts to adapt to testing equipment of different sizes and different foot layouts, so as to realize the rapid positioning, fixing and disassembly of large equipment. An unmanned material handling system consisting of track-mounted robots, fixed transfer robots, and multiple conveyor tracks is used to automatically complete sample entry, consumable replenishment, sample transfer, inspection operations, and waste removal processes after new equipment is loaded. The system integrates newly installed testing equipment into unmanned testing processes.
2. The unmanned biosafety testing container with rapid modification and refitting capabilities as described in claim 1, characterized in that, The specialized large-size airtight door adopts a multi-seal structure that meets the requirements of negative pressure laboratory levels, wherein: The door frame is welded from metal profiles into an integral frame, with reinforcing ribs on the inside to resist the deformation force generated by the negative pressure inside the cabin. The main door and the auxiliary door have a sandwich structure of composite skin and foam filling inside, and decorative strips are set on the outside to improve the sealing performance; The hinges are densely arranged, with at least three points on the upper part to resist the impact load when the equipment moves in and out. Limiting devices can restrict the opening angle of the door and prevent the door from colliding with equipment.
3. The unmanned biosafety testing cabin with rapid modification and refitting capabilities as described in claim 2, characterized in that, The adjustable device fixing device is a multi-layer slide rail composite structure, which includes: The bottom slide rail, fixed to the bottom plate of the cabin, extends longitudinally along the cabin, and multiple bottom slide nuts are pre-installed in the slide groove; The upper slide rail can move along the bottom slide rail, and its end is connected to the bottom slider nut by bolts to realize the longitudinal adjustment of the upper and lower slide rails; The upper part of the upper slide rail is equipped with an upper slider nut that slides laterally, which can achieve precise alignment of the equipment's foot holes in the lateral direction; Combined with a constant torque fastening process, it can ensure that testing equipment of different weights and structural forms remains stable and without displacement during transportation vibration, operational impact and long-term operation.
4. The unmanned biosafety testing container with rapid modification and refitting capabilities as described in claim 3, characterized in that, The adjustable equipment fixing device's slide rail matrix covers the main floor area of the biological laboratory workspace and provides efficient support for modification and upgrade operations in the following ways: The slide rails adopt a modular splicing method, and the coverage area can be adjusted according to the scale of the equipment; The slide rail is made of high-strength, corrosion-resistant alloy steel, and its surface is treated with a coating that resists corrosion in biological experimental environments.
5. The unmanned biosafety testing container with rapid modification and refitting capabilities as described in claim 4, characterized in that, The integrated system for unmanned processes of retrofitting and modifying equipment includes: The automatic device identification module can automatically identify new devices by reading device ID, model information, or connection protocol. The driver adaptation module automatically loads the control protocol of the specified device through the local device driver library; for devices without pre-installed drivers, it imports the new device driver package through the external data interface and completes the registration. The robot parameter learning module relies on the robot's end-effector vision recognition system to scan visual marks on new equipment and obtain the equipment's spatial posture, interface position, and operation port characteristics. The path planning module generates a new path for the coordinated work of the track-based robot and the stationary robot based on the spatial layout and operational requirements of the new equipment, and combines it with the motion library to form a new operating procedure. The closed-loop execution verification module performs a full-link simulation of the communication link, material logistics path, and complete detection process to verify whether the unmanned process is consistent.
6. The unmanned biosafety testing container with rapid modification and refitting capabilities as described in claim 5, characterized in that, The unmanned material transfer system includes: The sample transfer robot and sample transfer window in the sample temporary storage room are used to complete sample entry, temporary storage and transfer to the core testing area; Consumables transfer robots in the consumables storage and replacement room are used for automatic consumables replenishment; Waste treatment tanks are used to automatically collect, autoclave, and discharge waste. The track-mounted robot operates on a working track in the biological laboratory, undertaking operational tasks between core testing equipment, including sample transfer, consumable loading, reaction initiation, and product transfer.
7. The unmanned biosafety testing container with rapid modification and refitting capabilities as described in claim 6, characterized in that, The system is integrated after the new equipment is installed through the following steps: Equipment entry and airtightness restoration: After the dedicated large-size airtight door is opened, the equipment is pushed in, and the negative pressure environment inside the cabin is automatically restored after the installation is completed. Equipment spatial information acquisition: The robot vision system automatically scans the spatial coordinates, posture, and interface layout of the equipment. Driver loading and parameter registration: The system loads the driver or imports a new driver package based on the device model to complete the registration, and then adds the device to the global device list. The robot operation program is generated by the system's automatic job planning algorithm, which generates operation steps based on the equipment type, including grasping actions, interface plugging actions, and pick-and-place actions. The entire process is verified by simulating the complete "sample entry, equipment processing, and result output" process to verify the consistency of the process.
8. The unmanned biosafety testing container with rapid modification and refitting capabilities as described in claim 7, characterized in that, The modular shelter is equipped with standardized power interfaces, network interfaces, and data communication protocols, including: It adopts a standard data interface based on Ethernet to achieve high-speed communication with the central control system; Set up a redundant power supply system to ensure the continuity of power supply to the added equipment during operation; Multiple environmental monitoring sensors, including temperature sensors, differential pressure sensors, and humidity sensors, are deployed in the core experimental area of the middle layer to dynamically monitor the environment inside the chamber. Data is uniformly aggregated to the central control equipment for real-time analysis, ensuring that the equipment can be immediately integrated into the environmental monitoring closed-loop system after installation.
9. The unmanned biosafety testing cabin with rapid modification and refitting capabilities as described in claim 8, characterized in that, The modular unit has the capability to quickly replace functional modules for different testing tasks, including: Nucleic acid extraction and testing lines, rapid nucleic acid testing equipment, unmanned nucleic acid sequencers, pathogen screening equipment, and high-throughput automated equipment can be quickly replaced through adjustable fixing devices, standardized data interfaces, and unmanned integrated systems. It can be reconfigured according to the differences in sudden outbreaks, pathogen types, and testing tasks, enabling the mobile testing facility to be expanded from conventional testing mode to high-throughput mode, sequencing mode, or rapid screening mode.
10. An unmanned biosafety testing container with rapid modification capabilities as described in any one of claims 1-9, characterized in that, The mobile cabin has a complete biosafety environment protection system, including: The ventilation system and negative pressure control unit maintain the pressure gradient between the core experimental area and the outside, ensuring that aerosols do not leak out. Multiple buffer doors and pass-through windows ensure biosafety isolation during sample entry and exit. The disinfection system is used for terminal disinfection before equipment installation and environmental disinfection during process operation; The control system monitors and adjusts the cabin temperature, pressure, airflow, and filtration efficiency in real time.