Biopsy catheter entering cardiac muscle for sampling

Abstract

The biopsy catheter comprises a deep part and a pushing part, the deep part is arranged on the front section of the catheter and deep into the myocardium, the deep part comprises a connecting sleeve, a biopsy needle and a shearing sleeve, the biopsy needle and the shearing sleeve are coaxially matched in a sliding mode, and the connecting sleeve and the biopsy needle are matched in a sliding mode; the pushing part is arranged at the tail end of the guide pipe, the pushing part comprises a butt joint pipe, a push rod and a sliding sleeve, the butt joint pipe is in coaxial sliding fit with the push rod, and the push rod is in coaxial sliding fit with the sliding sleeve. The device has the beneficial effects that a springback sampling mode is adopted, so that the phenomenon that the device is not broken in the sampling process is avoided, the pain of a patient is reduced, the problems of limited sampling depth and high complication risk of a traditional biopsy technology are solved, the sampling efficiency and the operation convenience are improved through rotary shearing, and the labor intensity of the patient is reduced. And reliable technical support is provided for accurate diagnosis of myocardial diseases.

Description

Technical Field

[0001] This invention relates to the field of cardiac biopsy sampling technology, and in particular to a biopsy catheter for entering the myocardium to take samples. Background Technology

[0002] Accurate diagnosis of myocardial diseases is a crucial prerequisite for clinical treatment, while pathological analysis of myocardial tissue samples is the "gold standard" for identifying the cause, assessing the severity of the condition, and developing personalized treatment plans. Among various myocardial diseases, such as myocarditis, cardiomyopathy, myocardial fibrosis, and myocardial tumors, the pathological mechanisms are complex and the clinical manifestations are diverse. Relying solely on imaging examinations (such as echocardiography and cardiac MRI) or blood biochemical indicators is often insufficient for a clear diagnosis or accurate classification. Therefore, it is necessary to obtain myocardial tissue through biopsy for in-depth testing. Currently, the most commonly used clinical method for myocardial biopsy is percutaneous endocardial myocardial biopsy. This technique involves inserting biopsy forceps into the heart chamber via a venous or arterial route and, under X-ray fluoroscopy guidance, harvesting subendocardial myocardial tissue. However, this traditional method has several limitations: firstly, the sampling site is mostly limited to the subendocardial region, making it difficult to reach deep myocardium, which may lead to sampling errors and affect diagnostic accuracy; secondly, during the procedure, the forceps knot may open within the heart, potentially entangled in or accidentally clamping heart valves and chordae tendineae, causing damage and potentially leading to valvular insufficiency. Summary of the Invention

[0003] The purpose of this section is to outline some aspects of embodiments of the present invention and to briefly describe some preferred embodiments. Simplifications or omissions may be made in this section, as well as in the abstract and title of this application, to avoid obscuring the purpose of these documents; however, such simplifications or omissions should not be construed as limiting the scope of the invention.

[0004] In view of the problems of sampling bias and the potential for increased harm to patients during the sampling process in the above-mentioned or existing technologies, this invention is proposed.

[0005] Therefore, the object of the present invention is to provide a biopsy catheter for entering the myocardium to take samples.

[0006] To solve the above-mentioned technical problems, the present invention provides the following technical solution: a biopsy catheter for sampling into the myocardium, comprising a penetration portion disposed at the front end of the catheter and penetrating into the myocardium; the penetration portion comprising a connecting sleeve, a biopsy needle, and a shearing sleeve; the biopsy needle and the shearing sleeve slidingly engaging coaxially; and the connecting sleeve slidingly engaging with the biopsy needle; and, The pushing part is disposed at the end of the conduit. The pushing part includes a connecting pipe, a push rod and a sliding sleeve. The connecting pipe and the push rod are slidably coupled coaxially, and the push rod and the sliding sleeve are slidably coupled coaxially.

[0007] As a preferred embodiment of the biopsy catheter for intramyocardial sampling according to the present invention, the connecting sleeve includes a hollow cavity, a guide rail and a fitting groove. The hollow cavity is symmetrically arranged on both sides of the connecting sleeve, the guide rail is symmetrically arranged on both sides inside the connecting sleeve, and the fitting groove is arranged on the outside of the connecting sleeve.

[0008] As a preferred embodiment of the biopsy catheter for intramyocardial sampling according to the present invention, the biopsy needle includes an insertion tube, a guide groove, a sampling groove, a ball head, and an insertion head. The guide groove is symmetrically arranged on both sides of the biopsy needle, the insertion tube is located at the end of the biopsy needle, the sampling groove is located on the side of the biopsy needle, the ball head is symmetrically arranged on both sides of the biopsy needle, and the insertion head is located at the end of the biopsy needle.

[0009] As a preferred embodiment of the biopsy catheter for intramyocardial sampling according to the present invention, the shearing sleeve includes a locking ring disposed at its end, a transition ring disposed on its other side, and arc-shaped grooves symmetrically disposed on both sides of its interior.

[0010] As a preferred embodiment of the biopsy catheter for intramyocardial sampling described in this invention, wherein: the arc-shaped groove slides in conjunction with the ball head, and the locking ring slides in conjunction with the interlocking groove.

[0011] As a preferred embodiment of the biopsy catheter for entering the myocardium for sampling as described in this invention, wherein the guide rail and the guide groove are slidably engaged.

[0012] As a preferred embodiment of the biopsy catheter for intramyocardial sampling according to the present invention, the connecting tube includes a pushing cavity and a sliding cavity, the pushing cavity is disposed at the end of the sliding cavity, and pushing grooves are symmetrically arranged on both sides of the pushing cavity.

[0013] As a preferred embodiment of the biopsy catheter for intramyocardial sampling according to the present invention, the push rod includes a slide rod and a blocking ring, the blocking ring is disposed at the end of the slide rod, the other end of the slide rod is connected to the infiltration tube, the slide rod includes a reset spring disposed on its side, and the blocking ring has symmetrically arranged convex grooves on both sides.

[0014] As a preferred embodiment of the biopsy catheter for entering the myocardium for sampling according to the present invention, the sliding sleeve includes sliders symmetrically arranged on both sides thereon, a sliding hole is provided in the middle of the slider, and a top spring is provided inside the sliding hole.

[0015] As a preferred embodiment of the biopsy catheter for entering the myocardium for sampling according to the present invention, wherein: the sliding hole is slidably fitted with a squeezing block, the end of the squeezing block is provided with a convex slider, and the middle of the squeezing block is provided with a step that contacts the top spring.

[0016] The beneficial effects of this invention are: 1. In terms of sampling accuracy, this invention can overcome the limitations of the subendocardial region and, with the help of precise image-guided technology, directly puncture to the deep layer of the myocardium to achieve targeted sampling at specific depths and locations, effectively avoiding missed or misdiagnosis due to sampling deviations. It is especially suitable for the diagnosis of lesions such as focal myocarditis and myocardial amyloidosis. 2. In terms of operational safety, the minimally invasive design of the sampling needle can reduce mechanical damage to the endocardium and lower the risk of serious complications such as cardiac tamponade and arrhythmia. At the same time, a single sampling can obtain enough tissue to meet the testing requirements, reducing the surgical risks caused by repeated operations and providing patients with a safer diagnosis and treatment experience. Attached Figure Description

[0017] To more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings used in the description of the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort. Wherein: Figure 1 This is a schematic diagram of a biopsy catheter used to obtain samples from the myocardium.

[0018] Figure 2 This is a schematic diagram of the head of a biopsy catheter used to take samples from the myocardium.

[0019] Figure 3 This is a schematic diagram of the propulsion section of a biopsy catheter used for sampling inside the myocardium.

[0020] Figure 4 This is a schematic diagram of the propulsion assembly of a biopsy catheter used for sampling within the myocardium.

[0021] Figure 5 This is a schematic diagram of the propulsion structure of a biopsy catheter used for sampling within the myocardium.

[0022] Figure 6 This is a structural diagram of point A of a biopsy catheter used to obtain samples from the myocardium.

[0023] Figure 7 This is a structural diagram of point B of a biopsy catheter used for sampling inside the myocardium.

[0024] Figure 8 This is a structural diagram of point C of a biopsy catheter used for sampling inside the myocardium.

[0025] Figure 9 This is a structural diagram of point D of a biopsy catheter used for sampling inside the myocardium.

[0026] Figure 10 This is a structural diagram of point E of a biopsy catheter used for sampling inside the myocardium. Detailed Implementation

[0027] To make the above-mentioned objects, features and advantages of the present invention more apparent and understandable, the specific embodiments of the present invention will be described in detail below with reference to the accompanying drawings.

[0028] Many specific details are set forth in the following description in order to provide a full understanding of the invention. However, the invention may also be practiced in other ways different from those described herein, and those skilled in the art can make similar extensions without departing from the spirit of the invention. Therefore, the invention is not limited to the specific embodiments disclosed below.

[0029] Secondly, the term "one embodiment" or "embodiment" as used herein refers to a specific feature, structure, or characteristic that may be included in at least one implementation of the present invention. The phrase "in one embodiment" appearing in different places in this specification does not necessarily refer to the same embodiment, nor is it a single or selective embodiment that is mutually exclusive with other embodiments.

[0030] Example 1, referring to Figures 1-3 This is the first embodiment of the present invention. This embodiment provides a biopsy catheter for sampling inside the myocardium, which includes a penetration portion 100 and a pushing portion 200. The penetration portion 100 is disposed at the front end of the catheter and penetrates into the myocardium. The penetration portion 100 includes a connecting sleeve 101, a biopsy needle 102, and a shearing sleeve 103. The biopsy needle 102 and the shearing sleeve 103 are coaxially slidably engaged, and the connecting sleeve 101 is slidably engaged with the biopsy needle 102. The pushing portion 200 is disposed at the end of the catheter. The pushing portion 200 includes a connecting tube 201, a push rod 202, and a sliding sleeve 203. The connecting tube 201 and the push rod 202 are coaxially slidably engaged, and the push rod 202 and the sliding sleeve 203 are coaxially slidably engaged.

[0031] In use, the insertion section 100 of the catheter is first advanced along the vascular pathway to the target area of ​​the heart. The position of the connecting sleeve 101 is confirmed using image guidance, ensuring the biopsy needle 102 is aligned with the myocardial region to be sampled. Then, the pushing section 200 at the end of the catheter pushes the push rod 202, causing it to slide coaxially along the connecting tube 201. This extends the biopsy needle 102 of the insertion section 100 forward, penetrating the myocardial tissue to a preset depth, completing the puncture at the sampling site. The sliding sleeve 203 of the sliding pushing section 200, through a transmission structure, drives the shearing sleeve 103 of the insertion section 100 to slide coaxially along the biopsy needle 102. Using the cooperation of the shearing sleeve 103 and the biopsy needle 102, the myocardial tissue sample obtained by puncture is sheared and separated, remaining within the biopsy needle 102. After sampling, the push rod 202 is pulled back, causing the biopsy needle 102 to retract into the connecting sleeve 101, while simultaneously ensuring the shearing sleeve 103... The catheter is repositioned to prevent sample dislodgement. Finally, the entire catheter is withdrawn from the body, and the tissue sample inside the biopsy needle 102 is removed for pathological testing. The entire process achieves targeted acquisition of intramyocardial samples through precise control of the pushing part 200 and the penetrating part 100. The combination of minimally invasive design and coaxial sliding cooperation structure takes into account both the safety of the operation and the sampling efficiency.

[0032] Example 2, refer to Figures 3-10 This is the second embodiment of the present invention, which differs from the first embodiment in that it further includes a connecting sleeve 101, which includes a hollow cavity 101a, a guide slide rail 101b, and a fitting groove 101c. The hollow cavity 101a is symmetrically arranged on both sides of the connecting sleeve 101, the guide slide rail 101b is symmetrically arranged on both sides inside the connecting sleeve 101, and the fitting groove 101c is arranged on the outside of the connecting sleeve 101.

[0033] Furthermore, the biopsy needle 102 includes an insertion tube 102a, a guide groove 102b, a sampling groove 102c, a ball head 102d, and an insertion head 102e. The guide groove 102b is symmetrically arranged on both sides of the biopsy needle 102, the insertion tube 102a is located at the end of the biopsy needle 102, the sampling groove 102c is located on the side of the biopsy needle 102, the ball head 102d is symmetrically arranged on both sides of the biopsy needle 102, and the insertion head 102e is located at the end of the biopsy needle 102.

[0034] Preferably, the shear sleeve 103 includes a locking ring 103a disposed at one end, a transition ring 103b disposed on the other side, and arc-shaped grooves 103c symmetrically disposed on both sides inside. The arc-shaped grooves 103c are slidably engaged with the ball head 102d, the locking ring 103a is slidably engaged with the fitting groove 101c, and the guide rail 101b is slidably engaged with the guide groove 102b.

[0035] In the previous embodiment, a biopsy catheter for sampling into the myocardium includes a penetration portion 100 and a propulsion portion 200. The penetration portion 100 penetrates into the myocardial tissue, and the propulsion portion 200 provides assistance to the penetration portion 100, enabling the penetration portion 100 to accurately enter the myocardium.

[0036] Specifically, the ball head 102d slides into the arc-shaped grooves 103c on both sides of the shear sleeve 103. When the biopsy needle 102 reciprocates, the arc-shaped grooves 103c drive the shear sleeve 103 to rotate, making the shear sleeve 103 faster and more effective in sampling and reducing the phenomenon of myocardial cell adhesion.

[0037] In use, the insertion part 100 is first inserted into the heart to puncture the inner wall of the myocardial cells. Combined with techniques such as angiography, the insertion head 102e of the biopsy needle 102 reaches the lesion site. The cooperation between the guide groove 102b and the guide rail 101b ensures that the insertion head 102e does not make any unnecessary movements, avoiding discomfort to the patient. At the same time, during the insertion of the insertion head 102e, the sampling groove 102c extends from inside the shearing sleeve 103 and is exposed to the myocardial lesion site. Since the sampling groove 102c has a ring structure, the myocardial lesion cells will fill the sampling groove 102c. Then, when the biopsy needle 102 retracts, the arc groove 103c and the ball head 102d slide together, causing the shearing sleeve 103 to start rotating and shearing. At this time, the sample retained in the sampling groove 102c retracts into the shearing sleeve 103 to complete the sampling. The catheter can then be removed to complete the sample collection operation.

[0038] Example 3, referring to Figures 1-10 This is the third embodiment of the present invention, which differs from the previous two embodiments in that it also includes a connecting pipe 201 including a pushing cavity 201a and a sliding cavity 201b, the pushing cavity 201a being disposed at the end of the sliding cavity 201b, and the pushing cavity 201a having symmetrically arranged pushing grooves 201a-1 on both sides.

[0039] Furthermore, the push rod 202 includes a slide rod 202a and a blocking ring 202b. The blocking ring 202b is disposed at the end of the slide rod 202a, and the other end of the slide rod 202a is connected to the inlet tube 102a. The slide rod 202a includes a return spring 202a-1 disposed on its side, and the blocking ring 202b has convex grooves 202b-1 symmetrically disposed on both sides.

[0040] Preferably, the sliding sleeve 203 includes sliders 203a symmetrically arranged on both sides thereon. A sliding hole 203a-1 is provided in the middle of the slider 203a. A top spring 203a-2 is provided inside the sliding hole 203a-1. A pressing block 203b is slidably fitted into the sliding hole 203a-1. A convex slider 203b-1 is provided at the end of the pressing block 203b. A step is provided in the middle of the pressing block 203b to contact the top spring 203a-2.

[0041] Combining the previous two embodiments, the insertion part 100 is first inserted into the heart to puncture the inner wall of the myocardial cells. Combined with techniques such as angiography, the insertion head 102e of the biopsy needle 102 reaches the lesion site. The cooperation between the guide groove 102b and the guide rail 101b ensures that the insertion head 102e does not undergo any other unnecessary movements, avoiding discomfort to the patient. At the same time, during the insertion of the insertion head 102e, the sampling groove 102c extends from inside the shearing sleeve 103 and is exposed to the myocardial lesion site. Since the sampling groove 102c is a ring structure, the myocardial lesion cells will fill the sampling groove 102c. Then, when the biopsy needle 102 retracts, the arc groove 103c and the ball head 102d slide together, causing the shearing sleeve 103 to begin rotating and shearing. At this time, the sample retained in the sampling groove 102c retracts into the shearing sleeve 103 to complete the sampling. The catheter can then be removed to complete the sample collection operation.

[0042] Specifically, the biopsy catheter that enters the myocardium for sampling achieves accurate, safe, and efficient acquisition of myocardial samples through the coordinated operation of the insertion part 100 and the propulsion part 200. The structural optimization and functional upgrades of each embodiment have gradually improved the practicality of the device.

[0043] In the first two embodiments, the connecting sleeve 101, biopsy needle 102, and shearing sleeve 103 of the penetration section 100 are connected by a sliding engagement between the guide rail 101b and the guide groove 102b, a rotational engagement between the arc groove 103c and the ball head 102d, and a limiting engagement between the locking ring 103a and the interlocking groove 101c, ensuring the stability of the puncture and the reliability of the sampling. The sampling groove 102c of the biopsy needle 102 has a ring structure, which can naturally fill with tissue samples after puncturing the myocardial lesion. The rotational shearing design of the shearing sleeve 103 effectively reduces myocardial cell adhesion and improves sample retention rate. The guiding structure avoids unnecessary movements during the operation and reduces patient discomfort.

[0044] During the sampling process, the pushing unit pushes the push rod 202 via the squeezing block 203b on the sliding sleeve 203. The squeezing block 203b is lifted by the top spring 203a-2. Therefore, during the pushing process, the convex slider 203b-1 at the end of the squeezing block 203b does not engage with the convex grooves 202b-1 symmetrically arranged on both sides of the blocking ring 202b. At this time, the positional relationship is a misaligned structure, allowing the sliding sleeve 203 to be slowly pushed to allow the catheter to penetrate deeper into the heart. When it is determined that the sampling groove 102c is exposed within the myocardial cells, the squeezing block 203b on the sliding sleeve 203 is squeezed, causing the convex slider 203b-1 at its end to displace downwards. After displacement, it engages with the convex groove 202b-1. After the push rod 202 loses its constraint, it rebounds under the action of the reset spring 202a-1. At this moment, the insertion head 102e located at the end of the deep section 100 is pulled in a very short time, and the retraction completes the shearing and sampling. The catheter can then be withdrawn from the patient's body to complete the sampling. This rebound sampling method avoids indecisiveness during the sampling process, avoids continuous harm to the patient, and reduces patient pain. Through modular design and precise matching structure, this device not only solves the problems of limited sampling depth and high risk of complications in traditional biopsy technology, but also improves sampling efficiency and ease of operation through functions such as rotation shearing and automatic reset, providing reliable technical support for the accurate diagnosis of myocardial diseases.

[0045] In summary, this invention, through the sliding cooperation between the guide rail 101b of the deep insertion part 100 and the guide groove 102b of the biopsy needle 102, and the layered motion control structure of the pushing part 200, ensures that the insertion head 102e of the biopsy needle 102 can accurately reach the myocardial lesion site. This overcomes the limitation of limited sampling depth in traditional biopsy techniques, enabling targeted sampling of deep myocardial lesions and significantly reducing the risk of missed or misdiagnosis. The precise cooperation of each component effectively reduces unnecessary movements during operation, avoiding unnecessary damage to myocardial tissue. The rotational shearing design of the shearing sleeve 103 reduces myocardial cell adhesion and decreases mechanical stimulation during sample acquisition. In terms of ease of use and efficiency, the modular design of the insertion and propulsion sections facilitates operation by medical staff. The linkage control structure of the propulsion section 200 makes the puncture, sampling, and repositioning actions smooth and efficient. The annular sampling groove 102c can quickly fill tissue samples, shortening the operation time, improving sampling efficiency, and reducing patient pain. Furthermore, this device provides a reliable guarantee for the accurate diagnosis of myocardial diseases. By obtaining high-quality, precisely located myocardial tissue samples, it helps clinicians to clarify the etiology and accurately classify the disease, laying a solid foundation for developing personalized treatment plans and having significant clinical application value.

[0046] Example 4: This example provides a navigation process for entering the heart, referring to the previous three examples. Specifically, firstly, the image guidance system (such as an angiography machine or transesophageal echocardiography) is activated, and the equipment is calibrated to ensure clear visualization of the heart and vascular structures. Then, the fit of each component of the biopsy catheter is checked: ensuring that the biopsy needle 102 is retracted into the connecting sleeve 101 and the insertion head 102e is not exposed; that the locking ring 103a of the shear sleeve 103 is fully engaged with the fitting groove 101c of the connecting sleeve 101 to prevent loosening of components during navigation; that the reset spring 202a-1 of the pushing part 200 is in its natural state; that the squeezing block 203b of the sliding sleeve 203 is not pressed; and that the convex slider 203b-1 and the convex groove 202b-1 of the blocking ring 202b are misaligned.

[0047] Further, the patient undergoes preoperative preparation, and a puncture route (such as the femoral vein, jugular vein, or radial artery) is selected. After local anesthesia, vascular access is established, and a catheter sheath is inserted to reduce vascular damage.

[0048] Furthermore, hold the catheter pusher 200 in your hand and slowly insert the tip of the insertion part 100 into the blood vessel along the catheter sheath; at this time, the biopsy needle 102 is completely retracted into the hollow cavity 101a of the connecting sleeve 101 to avoid piercing the blood vessel wall. The catheter is advanced under image guidance, and the specific path is as follows. Advance the catheter along the venous / arterial route, prioritizing straight vessel segments, such as femoral vein → inferior vena cava → right atrium, and observe the catheter's course in real time via imaging; If the direction of the catheter tip needs to be adjusted, it can be achieved by adjusting the sliding sleeve 203 of the fine-tuning push part 200. When the sliding sleeve 203 is slightly slid, the slider 203a moves along the push groove 201a-1 of the connecting tube 201, which drives the connecting sleeve 101 of the insertion part 100 to adjust the angle (due to the difference in friction between the outside of the connecting sleeve and the blood vessel wall, the direction is corrected). If a blood vessel bifurcates or bends, after confirming this via imaging, pause the advance and gently pull the push rod 202. Utilize the elastic buffer of the reset spring 202a-1 to allow the front end of the connecting sleeve 101 to naturally conform to the curvature of the blood vessel wall, avoiding hard impact.

[0049] When the catheter tip is seen to be close to the heart on imaging, the advancement speed is reduced, and the distance between the catheter and the endocardium is monitored in real time via transesophageal echocardiography. At this time, the guide groove 102b of the biopsy needle 102 and the guide rail 101b of the connecting sleeve 101 maintain a sliding fit to ensure that the front end of the catheter is stable and without deviation.

[0050] When the front end of the connector sleeve 101 contacts the endocardium, the image shows that it adheres to the boundary of the endocardium and there is no obvious extravascular protrusion to avoid penetrating the myocardium. A slight push of the push rod 202 causes the biopsy needle 102 to move slightly forward and penetrate the head 102e without being exposed. The front end is kept stable by the locking action of the groove 101c of the connecting sleeve 101 and the locking ring 103a of the shear sleeve 103, thus preventing displacement due to heartbeat.

[0051] After confirming the accurate position, maintain the gripping force of the pusher 200 to fix the sliding sleeve 203 and the connecting tube 201 relatively. At this time, the tip of the catheter is stably attached to the endocardium, preparing for subsequent puncture and sampling.

[0052] Example 5: In the above four examples, further improvements are needed to the transition ring 103b. Specifically, a positioning confirmation component is added to the transition ring 103b of the shear sleeve 103. This component uses electrode monitoring or pressure feedback to resolve the problem of misjudgment of endocardial adhesion status and ensure the accuracy of sampling position. The specific structure and implementation process are as follows: Two microelectrodes are symmetrically embedded on the outer circumference of the transition ring 103b. The electrode material is a biocompatible metal such as platinum-iridium alloy, with an exposed area ≤0.5mm², to avoid interference with the rotation of the shear sleeve 103 and the movement trajectory of the arc groove 103c and the locking ring 103a.

[0053] Meanwhile, a miniature pressure sensor is embedded on the inner side of the transition ring 103b near the arc groove 103c. It adopts a piezoresistive thin film structure with a thickness of ≤0.3mm and the sensing surface faces the outer side of the connecting sleeve 101. It is used to detect the contact pressure between the transition ring and the endocardium.

[0054] The wires of the electrode and pressure sensor extend along the inner wall of the shear sleeve 103, pass through the hollow cavity 101a of the connecting sleeve 101, and finally connect to the signal interface at the end of the push part 200. The external monitoring host displays the impedance value and pressure value.

[0055] When the catheter reaches 100mm into the endocardium, the electrodes begin to contact the myocardial tissue. The electromyography (EMG) of the monopolar electrograph can determine whether the catheter has entered the myocardium.

[0056] When the pressure value of the pressure sensor stabilizes at 5-10g and is consistent with the electrode monitoring result, the positioning is confirmed to be accurate, and the sampling operation can be started as described in Examples 2 and 3, including biopsy needle puncture and sheath rotation.

[0057] If the electrode impedance and pressure value do not match, such as the impedance being normal but the pressure being <5g, it indicates that the transition ring 103b is tilted. It is necessary to fine-tune the sliding sleeve 203 through the pushing part 200 and use the slider 203a to slide along the pushing groove 201a-1 to correct the angle of the guide tube until both parameters meet the standards.

[0058] In compatibility with existing puncture structures, the electrodes and pressure sensors are small in size and do not affect the core functions of the shear sleeve 103: the sliding engagement of the locking ring 103a and the fitting groove 101c, and the rotational engagement of the arc groove 103c and the ball head 102d are not affected.

[0059] The wire is routed through the hollow cavity 101a, and there is no spatial conflict with the guide groove 102b of the biopsy needle 102 and the guide rail 101b of the connecting sleeve 101, ensuring the smooth sliding of the biopsy needle 102.

[0060] This embodiment adds dual electrodes and pressure components to the transition ring 103b to form a dual positioning verification of "electrophysiology + mechanics", which solves the problem of "visual fit but no actual contact" under simple image guidance, further improves the sampling success rate, is seamlessly compatible with the structural design of existing biopsy catheters, and enhances the reliability of clinical applications.

[0061] It is important to note that the constructions and arrangements of this application shown in several different exemplary embodiments are merely illustrative. Although only a few embodiments are described in detail in this disclosure, those who consult this disclosure will readily understand that many modifications are possible (e.g., changes in the size, dimensions, structure, shape, and proportions of various elements, as well as parameter values ​​(e.g., temperature, pressure, etc.), mounting arrangements, use of materials, color, orientation, etc.) without substantially departing from the novel teachings and advantages of the subject matter described in this application). For example, an element shown as integrally formed may be composed of multiple parts or elements, the position of elements may be inverted or otherwise altered, and the nature or number or position of discrete elements may be changed or altered. Therefore, all such modifications are intended to be included within the scope of the invention. The order or sequence of any process or method steps may be changed or rearranged according to alternative embodiments. In the claims, any "device plus function" clause is intended to cover the structure described herein that performs the function, and not only structurally equivalent but also equivalent in structure. Other substitutions, modifications, alterations, and omissions may be made in the design, operation, and arrangement of the exemplary embodiments without departing from the scope of the invention. Therefore, the present invention is not limited to the specific embodiments, but extends to various modifications that still fall within the scope of the appended claims.

[0062] Furthermore, in order to provide a concise description of exemplary embodiments, not all features of actual embodiments (i.e., those features that are not relevant to the best mode of carrying out the invention as currently considered, or those features that are not relevant to implementing the invention) may be omitted.

[0063] It should be understood that numerous specific implementation decisions can be made during the development of any practical implementation, such as in any engineering or design project. Such development efforts may be complex and time-consuming, but for those skilled in the art who benefit from this disclosure, the development effort will be a routine work of design, manufacturing, and production without requiring much experimentation.

[0064] It should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention and are not intended to limit it. Although the present invention has been described in detail with reference to preferred embodiments, those skilled in the art should understand that modifications or equivalent substitutions can be made to the technical solutions of the present invention without departing from the spirit and scope of the technical solutions of the present invention, and all such modifications or substitutions should be covered within the scope of the claims of the present invention.

Claims

1. A biopsy catheter for intramyocardial sampling, characterized by: The utility model relates to a kind of biopsy catheter, including, The push part (200) is arranged at the end of catheter, and the push part (200) includes butt joint pipe (201), push rod (202) and sliding sleeve (203), the butt joint pipe (201) is coaxially slidingly fitted with push rod (202), and push rod (202) and sliding sleeve (203) are coaxially slidingly fitted. The adapter sleeve (101) includes hollow cavity (101a), guide slide rail (101b) and embedded groove (101c), the hollow cavity (101a) is symmetrically arranged on both sides of adapter sleeve (101), the guide slide rail (101b) is symmetrically arranged on both sides inside adapter sleeve (101), and the embedded groove (101c) is arranged outside adapter sleeve (101).

2. A biopsy catheter for accessing a myocardial sample as defined in claim 1, wherein: The biopsy needle (102) includes deep pipe (102a), guide sliding groove (102b), sampling groove (102c), ball head (102d) and piercing head (102e), the guide sliding groove (102b) is symmetrically arranged on both sides of biopsy needle (102), the deep pipe (102a) is arranged at the end of biopsy needle (102), the sampling groove (102c) is arranged at the side of biopsy needle (102), the ball head (102d) is symmetrically arranged on both sides of biopsy needle (102), and the piercing head (102e) is arranged at the end of biopsy needle (102).

3. A biopsy catheter for accessing a myocardial sample as defined in claim 2, wherein: The shearing sleeve (103) includes clamping ring (103a) arranged at its end, transition ring (103b) arranged at its other side, and arc-shaped groove (103c) symmetrically arranged on both sides inside it.

4. A biopsy catheter for accessing a myocardial sample as defined in claim 3, wherein: The arc-shaped groove (103c) is slidingly fitted with the ball head (102d), and the clamping ring (103a) is slidingly fitted with the embedded groove (101c).

5. A biopsy catheter for accessing a myocardial sample according to claim 4, wherein: The guide slide rail (101b) is slidingly fitted with the guide sliding groove (102b).

6. A biopsy catheter for accessing a myocardial sample as defined in claim 5, wherein: The butt joint pipe (201) includes push cavity (201a) and sliding cavity (201b), the push cavity (201a) is arranged at the end of sliding cavity (201b), and push groove (201a-1) is symmetrically arranged on both sides of push cavity (201a).

7. A biopsy catheter for accessing a myocardial sample according to claim 6, wherein: The push rod (202) includes slide rod (202a) and blocking ring (202b), the blocking ring (202b) is arranged at the end of slide rod (202a), and the other end of slide rod (202a) is connected with deep pipe (102a), the slide rod (202a) includes reset spring (202a-1) arranged at its side, and convex groove (202b-1) is symmetrically arranged on both sides of blocking ring (202b).

8. A biopsy catheter for accessing a myocardial sample according to claim 7, wherein: ​ 9. A biopsy catheter for accessing a myocardial sample according to claim 8, wherein: The sliding sleeve (203) comprises sliding blocks (203a) symmetrically arranged on both sides of the sliding sleeve (203), and a sliding hole (203a-1) is arranged in the middle of the sliding block (203a), and a top spring (203a-2) is arranged in the inner side of the sliding hole (203a-1).

10. A biopsy catheter for accessing a myocardial sample according to claim 9, wherein: The sliding hole (203a-1) is slidably matched with an extrusion block (203b), the extrusion block (203b) is provided with a convex sliding block (203b-1) at the end, and a step is arranged in the middle of the extrusion block (203b) and is in contact with the top spring (203a-2).

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