Intraoperative nerve monitor anti-interference device and method based on adaptive filtering

Abstract

The invention relates to the technical field of medical instruments, in particular to an intraoperative nerve monitor anti-interference device and method based on self-adaptive filtering, the device comprises an anti-interference shell and a closed cover plate, the closed cover plate is fixedly connected with the top of the anti-interference shell through bolt sets arranged on the periphery, a monitor is placed in the anti-interference shell, and the anti-interference shell is fixedly connected with the closed cover plate through bolts arranged on the periphery of the closed cover plate. A positioning assembly used for stably limiting the monitor is further arranged on the periphery of the interior of the anti-interference shell. The anti-interference shell is of a three-layer structure comprising the protective frame, the heat dissipation cold frame and the electromagnetic shielding frame, and the electromagnetic shielding frame is provided with a carbon fiber reinforcing layer, a nickel-copper alloy conducting layer and a PEEK protective layer, so that liquid and instrument collision in an operation environment can be resisted, and external electromagnetic interference can be isolated; the positioning frame is adjusted to be tightly attached to the monitor through the inflation cavity, elastic allowance is reserved in cooperation with the adjusting spring and the damper, longitudinal buffering of the damping bottom pad and the limiting top plate is combined, and the influence of vibration in transportation and operation on the monitor can be reduced.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of medical devices, in particular to an intraoperative nerve monitor anti-interference device and method based on adaptive filtering. BACKGROUND

[0002] The intraoperative nerve monitor is a key device for monitoring the real-time nerve function state during surgery, which collects intraoperative nerve electrical signals to determine whether the nerve is damaged, and provides guidance for surgical operation. However, the surgical environment is complex, and there are a lot of electromagnetic interference (such as electromagnetic radiation generated by surgical instruments and high-frequency electric knives), power frequency interference (such as 50Hz power supply interference) and electrostatic interference, etc. These interferences will cause distortion of nerve electrical signals and decrease of signal-to-noise ratio, seriously affecting the monitoring accuracy of the monitor, and even misleading the surgical decision and causing medical risks.

[0003] The existing anti-interference method of intraoperative nerve monitor mainly adopts single shielding or fixed parameter filtering, which is difficult to dynamically adapt to the complex and variable interference environment, and the anti-interference effect is limited, and there are problems of signal distortion and insufficient monitoring accuracy. Therefore, an intraoperative nerve monitor anti-interference system capable of realizing multi-dimensional anti-interference and dynamically suppressing interference signals is needed to ensure the integrity of nerve electrical signals and monitoring accuracy. SUMMARY

[0004] The present application aims to provide an intraoperative nerve monitor anti-interference device and method based on adaptive filtering to solve the above technical defects.

[0005] In order to achieve the above effects, the technical solution adopted by the present application is: an intraoperative nerve monitor anti-interference device based on adaptive filtering, comprising an anti-interference shell and a closed cover plate, the closed cover plate is fixedly connected with the top of the anti-interference shell through the bolts around, the monitor is placed in the inside of the anti-interference shell, and a positioning assembly for stabilizing and limiting the monitor is further arranged around the inside of the anti-interference shell; A shock-absorbing bottom pad is arranged at the bottom of the monitor in the inside of the anti-interference shell, and the top of the shock-absorbing bottom pad is in contact with the bottom of the monitor; a limiting top plate is movably arranged below the closed cover plate, limiting springs are fixedly arranged around the top of the limiting top plate, and the top ends of the four limiting springs are fixedly connected with the bottom of the closed cover plate; the anti-interference shell is composed of a protective frame, a heat dissipation cold frame and an electromagnetic shielding frame; An adaptive filtering anti-interference system is further arranged in the inside of the anti-interference shell, the adaptive filtering anti-interference system comprises a signal acquisition module, an adaptive filtering processing module, a signal output module, a power anti-interference module and a central control module.

[0006] Preferably, the anti-interference shell bottom is also provided with anti-skid supporting blocks around, and the bottom of the four anti-skid supporting blocks is provided with a silica gel sleeve.

[0007] Preferably, the protective frame is arranged at the outermost layer, the inner layer of the protective frame is provided with a heat dissipation cold frame, and the inner layer of the heat dissipation cold frame is provided with an electromagnetic shielding frame; the electromagnetic shielding frame adopts a three-layer gradient structure of a carbon fiber reinforced layer, a nickel-copper alloy conductive layer and a PEEK protective layer.

[0008] Preferably, the heat dissipation cold frame is provided with a plurality of heat dissipation fins on both sides, and the heat dissipation fins on both sides penetrate the inside of the protective frame and extend to the outside; the heat dissipation cold frame is provided with a circulating cooling flow channel on both sides, and the heat dissipation fins on both sides extend to the inside of the circulating cooling flow channel; the electromagnetic shielding frame is fixedly provided with a micro circulating pump on both sides, and the water inlet ends of the micro circulating pumps on both sides are in communication with the inside of the circulating cooling flow channel.

[0009] Preferably, the monitoring instrument is provided with a circulating cooling pipe on both sides, and the two ends of the circulating cooling pipe on both sides extend to the two sides of the monitoring instrument; one end of the circulating cooling pipe on the left side is in communication with the inside of the circulating cooling flow channel on the left side, and the other end is in communication with the water inlet end of the micro circulating pump on the left side; one end of the circulating cooling pipe on the right side is in communication with the inside of the circulating cooling flow channel on the right side, and the other end is in communication with the water inlet end of the micro circulating pump on the right side.

[0010] Preferably, the anti-interference shell is fixedly provided with a heat dissipation flow guide frame on both sides, and the heat dissipation flow guide frame is provided with a flow guide opening on the side close to the anti-interference shell; one side of the heat dissipation fin extends to the inside of the flow guide opening, and one side of the heat dissipation flow guide frame is fixedly provided with an axial flow fan, and the blowing end of the axial flow fan is in communication with the inside of the flow guide opening.

[0011] Preferably, the positioning assembly comprises a fixed frame and a positioning frame, the inside of the anti-interference shell is fixedly provided with a fixed frame around, and the four fixed frames are located on the upper end face of the shock-absorbing bottom pad; the inside of the fixed frame is provided with an inflation cavity, and the top of the fixed frame is sealingly provided with a sealing plate; the top of the sealing plate is fixedly provided with an adjusting air pump, and the output end of the adjusting air pump extends to the inside of the inflation cavity.

[0012] Preferably, one side of the fixed frame is movably provided with a positioning frame, and the two sides of the positioning frame are fixedly provided with adjusting springs; the inside of the adjusting spring is also provided with a damper, and one end of the adjusting spring is fixedly connected with the inner side wall of the fixed frame; the two sides of the positioning frame are fixedly provided with closed rubber sleeves, and one side of the two closed rubber sleeves is fixedly connected with the side wall of the fixed frame.

[0013] Preferably, the output end of the signal acquisition module is connected with the input end of the adaptive filtering processing module, the output end of the adaptive filtering processing module is connected with the input end of the signal output module, the power anti-interference module is electrically connected with each module and provides stable power supply, and the central control module is in communication connection with the signal acquisition module, the adaptive filtering processing module, the signal output module and the power anti-interference module for coordinating the work of each module.

[0014] Preferably, the anti-interference method of the intraoperative nerve monitor based on adaptive filtering is applied to the anti-interference device of the intraoperative nerve monitor based on adaptive filtering and comprises the following steps. The anti-interference shell is placed on a stable area through the bottom anti-skid supporting block, the monitor is placed on the shock-absorbing bottom pad after the closed cover plate is disassembled, the adjusting air pump of the positioning assembly is started to inflate the inflation cavity, the positioning frame is tightly attached to the side wall of the monitor and the elastic allowance is reserved through the adjusting spring, the closed cover plate is closed to make the limiting top plate cooperate with the limiting spring to limit the monitor in the longitudinal direction; The amplification multiple, the filter cutoff frequency of the signal acquisition module, the LMS algorithm parameter of the adaptive filtering processing module and the output voltage of the power anti-interference module are set through the central control module, and the line connection state of each module is checked; The micro circulating pump and the axial flow fan form a heat dissipation loop, the nerve electric signal is collected through the shielded platinum electrode, is transmitted to the adaptive filtering processing module after differential amplification and pre-filtering to dynamically suppress interference, is transmitted to the monitor by the RS485 driving chip after signal isolation and waveform shaping, and the central control module monitors the state of each module in real time and processes the exception.

[0015] Compared with the prior art, the anti-interference device of the intraoperative nerve monitor based on adaptive filtering has the following beneficial effects: 1. The anti-interference shell adopts the three-layer structure of the protective frame, the heat dissipation cold frame and the electromagnetic shielding frame, the carbon fiber reinforced layer, the nickel-copper alloy conductive layer and the PEEK protective layer of the electromagnetic shielding frame can resist liquid in the surgical environment, instrument collision and external electromagnetic interference; the positioning assembly adjusts the positioning frame to tightly attach to the monitor through the inflation cavity, the elastic allowance is reserved through the adjusting spring and the damper, the longitudinal buffer of the shock-absorbing bottom pad and the limiting top plate, the influence of transportation and intraoperative vibration on the monitor can be reduced, the silica gel sleeve of the anti-skid supporting block further avoids the sliding of the device when placed, and a stable environment is provided for equipment operation from the physical layer.

[0016] 2、In the signal acquisition stage, the shielding type platinum electrode reduces electrostatic interference through the grounding shielding layer, and the differential amplification circuit and the pre low-pass filter circuit preliminarily suppress common-mode interference and high-frequency noise; in the processing stage, the adaptive filtering module based on the LMS algorithm can dynamically adjust the filtering coefficient, cooperate with the real-time operation of the high-speed digital signal processor, and can specifically suppress the power frequency and electromagnetic interference changing in the operation; the data buffer unit guarantees the signal continuity; in the output stage, the optical coupling isolation circuit avoids interference conduction, and the Schmidt trigger corrects the waveform distortion; at the same time, the power anti-interference module provides interference-free power supply for each module through EMI filtering and stable voltage, and the real-time monitoring and fault processing of the central control module further ensure that the system anti-interference function is stable and effective, which guarantees the integrity of the neural electrical signal from signal acquisition to output.

[0017] 3, Through the loop cooling pipe inside the monitor adheres to the circuit board and adopts the tree-shaped shunt structure, the heat can be efficiently absorbed, the micro circulating pump drives the cooling liquid to circulate in the flow channel of the heat dissipation cold frame, and the heat is conducted to the outside through the heat dissipation fins; the axial flow fan on the both sides of the anti-interference shell forcibly blows the heat dissipation fins through the guide opening of the guide frame, so that the heat dissipation is accelerated, the performance of the circuit board is prevented from being reduced due to overheating, and the adaptive filtering system and the core components of the monitor can always maintain stable anti-interference ability and monitoring precision during long-time operation in the operation. BRIEF DESCRIPTION OF DRAWINGS

[0018] In order to more clearly illustrate the technical solutions of the embodiments of the present application, the following will briefly introduce the drawings needed to be used in the embodiments, and it should be understood that the following drawings only represent some embodiments of the present application, and should not be regarded as a limitation on the scope, and for those skilled in the art, other related drawings can also be obtained without creative labor on the basis of these drawings.

[0019] Figure 1 It is a schematic diagram of the anti-interference device structure of the intraoperative neural monitor based on adaptive filtering in the embodiment of the present application; Figure 2 It is a schematic diagram of the anti-interference shell and the monitor structure in the embodiment of the present application; Figure 3 It is a schematic diagram of the monitor and the limiting top plate structure in the embodiment of the present application; Figure 4 It is a schematic diagram of the internal structure of the anti-interference shell in the embodiment of the present application; Figure 5 It is a schematic diagram of the positioning assembly structure in the embodiment of the present application; Figure 6 It is a schematic diagram of the anti-interference shell and the heat dissipation guide frame structure in the embodiment of the present application; Figure 7 It is a principle block diagram of the adaptive filtering anti-interference system in the embodiment of the present application.

[0020] In the figure, 1, anti-interference shell; 2, closed cover plate; 3, monitor; 4, shock-absorbing bottom pad; 5, positioning assembly; 6, limiting top plate; 7, limiting spring; 8, anti-skid support block; 9, fixing frame; 10, inflation cavity; 11, adjusting air pump; 12, sealing plate; 13, positioning frame; 14, closed rubber sleeve; 15, adjusting spring; 16, protection frame; 17, heat dissipation cold frame; 18, electromagnetic shielding frame; 19, embedded interface; 20, heat dissipation fin; 21, heat dissipation guide frame; 22, guide port; 23, axial flow fan; 24, micro circulating pump; 25, circulating cooling pipe. DETAILED DESCRIPTION

[0021] The application will be further explained in conjunction with the accompanying drawings and specific embodiments.

[0022] Embodiment 1 Please refer to Figures 1 to 6 As shown in the figure, the embodiment discloses an intraoperative nerve monitor anti-interference device based on adaptive filtering, which comprises an anti-interference shell 1 and a closed cover plate 2. The closed cover plate 2 is fixedly connected with the top of the anti-interference shell 1 through bolts arranged around the periphery, and a handle is further fixedly arranged on the top of the closed cover plate 2. Anti-skid support blocks 8 are further fixedly arranged around the periphery of the bottom of the anti-interference shell 1, and a silica gel sleeve is arranged at the bottom of each of the four anti-skid support blocks 8. The handle can be used to conveniently carry and transfer the device as a whole. When the device is placed, the anti-skid support blocks 8 around the periphery of the bottom of the anti-interference shell 1 are brought into contact with the placement plane, and the silica gel sleeves arranged at the bottom of the anti-skid support blocks 8 are used to ensure the stability of the device when placed. The silica gel sleeves can increase the friction between the device and the placement plane, so as to effectively solve the problem of position sliding and deviation of the device when placed.

[0023] Further, the monitor 3 is placed in the anti-interference shell 1, and a positioning assembly 5 for stably limiting the monitor 3 is further arranged around the periphery of the inside of the anti-interference shell 1. The four positioning assemblies 5 are used to dynamically shock-absorb the monitor 3, so as to reduce the influence of vibration on the monitor 3 when working.

[0024] Further, the anti-interference shell 1 is internally provided with a shock-absorbing bottom pad 4 at the bottom of the monitor 3, and the top of the shock-absorbing bottom pad 4 is in contact with the bottom of the monitor 3; the bottom of the monitor 3 is supported by the shock-absorbing bottom pad 4, and the shock-absorbing bottom pad 4 provides a shock buffering force for the monitor 3 against vertical vibration. A limiting top plate 6 is movably arranged below the closed cover plate 2, limiting springs 7 are fixedly arranged around the top of the limiting top plate 6, the top ends of the four limiting springs 7 are fixedly connected with the bottom of the closed cover plate 2, and dampers are arranged in the four limiting springs 7. After the top of the closed cover plate 2 and the anti-interference shell 1 are assembled, the bottom of the limiting top plate 6 is in contact with the top of the monitor 3, the top of the monitor 3 is limited by the limiting top plate 6, and the limiting springs 7 and the dampers arranged at the top of the limiting top plate 6 play a shock buffering role when the monitor 3 is subjected to a vertical vibration force.

[0025] Further, the anti-interference shell 1 is composed of a protective frame 16, a heat dissipation cold frame 17 and an electromagnetic shielding frame 18. The protective frame 16 is arranged at the outermost layer, the heat dissipation cold frame 17 is arranged at the inner layer of the protective frame 16, and the electromagnetic shielding frame 18 is arranged at the inner layer of the heat dissipation cold frame 17. The electromagnetic shielding frame 18 adopts a three-layer gradient structure of a carbon fiber reinforced layer, a nickel-copper alloy conductive layer and a PEEK protective layer. The carbon fiber reinforced layer has a thickness of 2 mm, uses T700-grade carbon fiber, realizes conductive continuity through surface chemical copper plating, and has structural support and initial electromagnetic shielding capacity. The nickel-copper alloy conductive layer has a thickness of 0.05 mm, a composition of nickel 65% and copper 35%, and a shielding effectiveness of 1 GHz radio frequency interference of ≥65 dB. The PEEK protective layer has a thickness of 1.5 mm, uses medical-grade polyether ether ketone material, is resistant to chemical corrosion, has excellent biocompatibility, and resists liquid and instrument collision in the surgical environment as an outer protective layer. The heat dissipation cold frame 17 is provided with a plurality of heat dissipation fins 20 at both sides, and the heat dissipation fins 20 at both sides penetrate the inside of the protective frame 16 and extend to the outside. The heat dissipation cold frame 17 is provided with circulating cooling flow channels at both sides, and the heat dissipation fins 20 at both sides extend to the inside of the circulating cooling flow channels. The electromagnetic shielding frame 18 is fixedly provided with micro circulating pumps 24 at both sides, and the water delivery ends of the micro circulating pumps 24 at both sides are in communication with the inside of the circulating cooling flow channels at both sides. The monitor 3 is provided with circulating cooling pipes 25 at both sides, and both ends of the circulating cooling pipes 25 at both sides extend to both sides of the monitor 3. One end of the circulating cooling pipe 25 at the left side is in communication with the inside of the circulating cooling flow channel at the left side, and the other end is in communication with the water inlet end of the micro circulating pump 24 at the left side. One end of the circulating cooling pipe 25 at the right side is in communication with the inside of the circulating cooling flow channel at the right side, and the other end is in communication with the water inlet end of the micro circulating pump 24 at the right side.

[0026] It should be noted that the circulating cooling pipes 25 arranged on both sides of the monitor 3 are attached to the back of the circuit board, and adopt a tree-shaped shunt structure, and the structure on the back of the circuit board is provided with four direct currents to increase the contact area with the circuit board; the cooling liquid in the circulating cooling pipes 25 is selected from deionized water and a 5% propylene glycol solution, and when the monitor 3 is running, the heat inside the monitor 3 is cooled by the micro circulating pump 24 and the circulating cooling pipe 25 arranged on both sides, and the cooling liquid in the circulating cooling flow channel is cooled by the heat dissipation fin 20, thereby effectively ensuring the continuous cooling effect of the cooling liquid on the circuit board inside the monitor 3.

[0027] Further, in order to further improve the heat dissipation effect of the circuit board inside the monitor 3, the anti-interference shell 1 is fixedly provided with heat dissipation guide frames 21 on both sides, and the two heat dissipation guide frames 21 are provided with guide openings 22 on the side close to the anti-interference shell 1; one side of the heat dissipation fin 20 extends to the inside of the guide opening 22, and one side of the heat dissipation guide frame 21 is fixedly provided with an axial flow fan 23, and the blowing end of the axial flow fan 23 communicates with the inside of the guide opening 22.

[0028] It should be noted that the axial flow fan 23 blows air into the inside of the guide opening 22, and the airflow blows the heat on the heat dissipation fin 20, thereby more effectively cooling the circuit board of the monitor 3 during operation.

[0029] Embodiment 2 Specifically, the positioning assembly 5 includes a fixed frame 9 and a positioning frame 13, and the fixed frame 9 is fixedly arranged around the inside of the anti-interference shell 1, and the four fixed frames 9 are located on the upper end face of the shock-absorbing bottom pad 4, the inside of the fixed frame 9 is provided with an inflation cavity 10, and the top of the fixed frame 9 is sealingly provided with a sealing plate 12, the top of the sealing plate 12 is fixedly provided with an adjusting air pump 11, and the output end of the adjusting air pump 11 extends into the inside of the inflation cavity 10; wherein the top of the sealing plate 12 is also provided with an exhaust valve.

[0030] Further, the fixed frame 9 is movably provided with a positioning frame 13 on one side, and the positioning frame 13 is fixedly provided with an adjusting spring 15 on both sides, the inside of the adjusting spring 15 is also provided with a damper, and one end of the adjusting spring 15 is fixedly connected with the inner side wall of the fixed frame 9; the positioning frame 13 is fixedly provided with a closed rubber sleeve 14 on both sides, and one side of the two closed rubber sleeves 14 is fixedly connected with the side wall of the fixed frame 9.

[0031] It should be noted that after the monitor 3 is placed inside the anti-interference shell 1, the four positioning frames 13 are respectively located around the monitor 3, at this time, the adjusting air pump 11 at the top of the four fixing frames 9 is inflated to the inside of the inflation cavity 10, by adjusting the air pressure inside the inflation cavity 10, the side of the positioning frame 13 is tightly attached to the surface of the monitor 3, by adjusting the spring 15 and the damping device, a flexible margin is left for the four positioning frames 13 to the lateral positioning of the monitor 3 inside the anti-interference shell 1, so as to solve the problem that when the monitor 3 is impacted, the flexible margin of the positioning frame 13 plays a dynamic protection for the monitor 3.

[0032] Embodiment 3 Please refer to Figure 7 As shown, specifically, the inside of the anti-interference shell 1 is also provided with an adaptive filtering anti-interference system, the adaptive filtering anti-interference system includes a signal acquisition module, an adaptive filtering processing module, a signal output module, a power anti-interference module and a central control module; specifically, the signal acquisition module, the adaptive filtering processing module, the signal output module, the power anti-interference module and the central control module are integrated and connected through a circuit board, and are integrally placed in the anti-interference shell.

[0033] The output end of the signal acquisition module is connected with the input end of the adaptive filtering processing module, the output end of the adaptive filtering processing module is connected with the input end of the signal output module, the power anti-interference module is electrically connected with each module and provides stable power supply, and the central control module is in communication connection with the signal acquisition module, the adaptive filtering processing module, the signal output module and the power anti-interference module, and is used for coordinating the work of each module.

[0034] The signal acquisition module includes a shielded neural electric signal sensor, the sensor is provided with a metal shielding layer, the metal shielding layer is grounded, and is used for adhering to a neural monitoring part to collect a neural electric signal; a differential amplification circuit, an instrument amplifier is adopted, and is used for differentially amplifying and processing the collected neural electric signal and suppressing common-mode interference; and a pre-stage low-pass filter circuit, an RC active filter structure is adopted, and is used for preliminarily filtering high-frequency noise in the neural electric signal.

[0035] Specifically, the shielded neural electric signal sensor is a platinum electrode, the differential amplification circuit adopts an INA128 instrument amplifier, the amplification multiple is set to 1000 times, and the cut-off frequency of the pre-stage low-pass filter circuit is set to 1 kHz.

[0036] The adaptive filtering processing module includes a high-speed digital signal processor, which is used for real-time operation processing of the amplified and filtered neural electric signal; an adaptive filtering algorithm chip, which is internally provided with a least mean square adaptive filtering algorithm, is used for real-time adjustment of a filtering coefficient and dynamic suppression of power frequency interference and electromagnetic interference; and a data buffer unit, which adopts an SRAM chip, is used for temporarily storing collected original signals and processed signals, and guarantees data transmission continuity.

[0037] The signal output module comprises a signal isolation circuit, an optical coupling isolation chip is adopted, which is used for realizing electrical isolation of input signals and output signals, avoiding interference conduction; a post shaping circuit, a Schmitt trigger is adopted, which is used for correcting waveform distortion of processed signals, ensuring signal integrity; and an interface driving circuit, an RS485 driving chip is adopted, which is used for matching a signal interface of the intraoperative nerve monitor, enhancing signal transmission capacity.

[0038] Specifically, the signal isolation circuit adopts a 6N137 optical coupling isolation chip, and the interface driving circuit adopts an RS485 bus driving chip.

[0039] The power anti-interference module comprises an EMI filter, a double-stage common-mode choke structure is adopted, which is used for filtering electromagnetic interference on a power line; a linear voltage stabilizing circuit, an LDO stabilizer is adopted, which is used for outputting a stable working voltage; and a power monitoring circuit, a voltage detection chip is adopted, which is used for monitoring a power working state in real time, outputting an alarm signal when an abnormality occurs.

[0040] Specifically, the insertion loss of the EMI filter is greater than or equal to 40 dB, the linear voltage stabilizing circuit outputs ±5V and ±12V voltages, the output ripple is less than or equal to 10 mV, and the microcontroller adopts an STM32F103 chip.

[0041] The central control module comprises a microcontroller, which is used for receiving external instructions, coordinating working time sequences of various modules and processing state feedback signals of various modules; a communication interface circuit, a CAN bus interface is adopted, which is used for realizing instruction interaction and data transmission with external equipment; and a fault detection circuit, which is used for monitoring working currents and signal amplitudes of various modules in real time, triggering module reset or alarm when an abnormality occurs.

[0042] Embodiment 4 Specifically, the embodiment also discloses an intraoperative nerve monitor anti-interference method based on adaptive filtering, which is applied to the anti-interference device based on adaptive filtering of the intraoperative nerve monitor and specifically comprises the following steps. Step 1: Place the anti-interference shell 1 in a stable area in the operating room, contact the bottom four anti-skid supporting blocks 8 with the placement plane, increase the friction force by using the silica gel sleeve at the bottom of the anti-skid supporting block 8, and avoid the device from sliding and deviating; if the device needs to be moved, carry it by the handle at the top of the closed cover plate 2, and adjust it to a stable state after carrying; unscrew the bolt set around the closed cover plate 2, separate the closed cover plate 2 from the anti-interference shell 1, and expose the internal space of the anti-interference shell 1, to prepare for subsequent monitor installation.

[0043] Step 2: Lay the shock-absorbing bottom pad 4 on the inside bottom of the anti-interference shell 1, make sure the shock-absorbing bottom pad 4 is flat and wrinkle-free, then place the monitor 3 on the top of the shock-absorbing bottom pad 4, make the bottom of the monitor 3 fully contact with the shock-absorbing bottom pad 4, the shock-absorbing bottom pad 4 can buffer the vertical vibration; start the adjusting air pump 11 on the top of the fixed frame 9 in the positioning assembly 5, inflate the air chamber 10 inside the fixed frame 9, observe the movement state of the positioning frame 13, until one side of the positioning frame 13 closely adheres to the side wall of the monitor 3; if the inflation is excessive, adjust by deflating through the exhaust valve on the top of the sealing plate 12; the adjusting spring 15 on both sides of the positioning frame 13 stretches or compresses with the movement of the positioning frame 13, reserves elastic allowance for the lateral positioning of the monitor 3, at the same time, seals the gap between the positioning frame 13 and the fixed frame 9 through the closed rubber sleeve 14, avoids dust or liquid from entering; cover the closed cover plate 2 on the top of the anti-interference shell 1 again, tighten the bolt set; at this time, the bottom of the limiting top plate 6 under the closed cover plate 2 contacts with the top of the monitor 3, the limiting spring 7 around the top of the limiting top plate 6 is compressed to generate reverse elastic force, the limiting top plate 6 longitudinally limits the monitor 3, buffers the vertical vibration force; Step 3: Confirm that the signal acquisition module, adaptive filtering processing module, signal output module, power anti-interference module and central control module of the adaptive filtering anti-interference system have been connected through the circuit board integration, and are placed inside the anti-interference shell 1; check the connection state of each module line, make sure that the output end of the signal acquisition module, the input end of the adaptive filtering processing module, the output end of the adaptive filtering processing module, the input end of the signal output module, and the power supply end of the power anti-interference module are all firmly connected; send initialization instructions to each module through the microcontroller of the central control module: set the amplification factor of the differential amplification circuit in the signal acquisition module to 1000 times, and the cutoff frequency of the pre-low-pass filter circuit to 1 kHz; start the least mean square adaptive filtering algorithm of the adaptive filtering processing module, initialize the operation parameters of the high-speed digital signal processor, and set the storage rules of the data buffer unit; configure the working mode of the EMI filter in the power anti-interference module, set the output voltage of the linear voltage stabilizing circuit to ±5V and ±12V, and the output ripple to ≤10mV; Step 4: Start the micro circulating pump 24 on both sides of the electromagnetic shielding frame 18 inside the anti-interference shell 1, so that the cooling liquid in the circulating cooling pipe 25 starts to circulate; the cooling liquid flows from the water inlet end of the micro circulating pump 24 into the circulating cooling flow channel of the heat dissipation cold frame 17, then absorbs the heat of the circuit board after flowing through the circulating cooling pipe 25, and finally returns to the water outlet end of the micro circulating pump 24, forming a cooling loop; turn on the axial flow fan 23 on both sides of the heat dissipation guide frame 21 of the anti-interference shell 1, so that the axial flow fan 23 blows air into the guide port 22; the airflow acts on the heat dissipation fins 20 extended to the inside through the guide port 22, carries away the heat of the cooling liquid on the heat dissipation fins 20, and ensures that the cooling liquid maintains a low-temperature cooling effect; Step 5: nerve electrical signal acquisition and preliminary anti-interference: the shielded nerve electrical signal sensor of the signal acquisition module is attached to the nerve of the surgical site, the metal shielding layer of the sensor is grounded to avoid static interference; after the collected nerve electrical signal is inhibited by the differential amplification circuit, the high-frequency noise is filtered by the pre low-pass filter circuit to complete the preliminary anti-interference processing; the signal after preliminary processing is transmitted to the adaptive filtering processing module, the high-speed digital signal processor calculates the signal data in real time, the adaptive filtering algorithm chip dynamically adjusts the filtering coefficient according to the change of power frequency interference and electromagnetic interference in the signal, and suppresses the interference signal through the LMS algorithm; during the processing, the data buffer unit temporarily stores the original signal and the processed signal to ensure data continuity; the effective signal after processing enters the signal output module, realizes electrical isolation through the signal isolation circuit to avoid interference conduction; then the waveform distortion is corrected by the post shaping circuit, and finally the interface driving circuit matches the monitor 3 interface to transmit the stable signal to the monitor 3 display and analysis unit; the central control module receives the state feedback signal of each module in real time through the CAN bus interface, the power supply monitoring circuit monitors the power voltage and current, and the fault detection circuit monitors the working current and signal amplitude of each module; if power supply abnormality, module failure or signal abnormality occurs, the central control module immediately triggers module reset or sends an alarm signal to ensure stable operation of the system. Step 6: after the operation is completed, the power of each module of the adaptive filtering anti-interference system is turned off first, then the micro circulating pump 24 and the axial flow fan 23 are turned off, and after the cooling liquid stops circulating and the heat dissipation fin 20 cools down, the overall power supply is disconnected.

[0044] Meanwhile, the contents not described in detail in the specification all belong to the prior art known by those skilled in the art.

[0045] The present application is not limited to the above-mentioned optional embodiments, and anyone can derive other various forms of products under the inspiration of the present application. The above specific embodiments should not be understood as limiting the protection scope of the present application, and the protection scope of the present application should be defined by the claims, and the specification can be used to explain the claims.

Claims

1. An anti-interference device for intraoperative neuromonitoring based on adaptive filtering, comprising an anti-interference shell (1) and a closed cover plate (2), the closed cover plate (2) being fixedly connected with the top of the anti-interference shell (1) through a bolt set arranged around, characterized in that: The inside of the anti-interference shell (1) is provided with a monitor (3), and the periphery of the inside of the anti-interference shell (1) is further provided with a positioning assembly (5) for stably limiting the monitor (3); ​ The bottom of the inside of the anti-interference shell (1) is provided with a shock-absorbing bottom pad (4), and the top of the shock-absorbing bottom pad (4) is in contact with the bottom of the monitor (3); the lower side of the closed cover plate (2) is movably provided with a limiting top plate (6), the periphery of the top of the limiting top plate (6) is fixedly provided with a limiting spring (7), and the top end of the four limiting springs (7) is fixedly connected with the bottom of the closed cover plate (2); the anti-interference shell (1) is composed of a protective frame (16), a heat dissipation cold frame (17) and an electromagnetic shielding frame (18); The inside of the anti-interference shell (1) is further provided with an adaptive filtering anti-interference system, which comprises a signal acquisition module, an adaptive filtering processing module, a signal output module, a power anti-interference module and a central control module.

2. The adaptive filter based intraoperative neuromonitoring anti-jamming device of claim 1, wherein: The bottom of the anti-interference shell (1) is further provided with a anti-skid support block (8), and the bottom of the four anti-skid support blocks (8) is provided with a silica gel sleeve.

3. The adaptive filter based intraoperative neuromonitoring anti-jamming device of claim 1, wherein: The protective frame (16) is arranged in the outermost layer, the inner layer of the protective frame (16) is provided with the heat dissipation cold frame (17), and the inner layer of the heat dissipation cold frame (17) is provided with the electromagnetic shielding frame (18); the electromagnetic shielding frame (18) adopts a three-layer gradient structure of a carbon fiber reinforced layer, a nickel-copper alloy conductive layer and a PEEK protective layer.

4. The adaptive filter-based intraoperative neuromonitoring anti-jamming device of claim 3, wherein: The two sides of the heat dissipation cold frame (17) are provided with a plurality of heat dissipation fins (20), and the heat dissipation fins (20) on the two sides penetrate the inside of the protective frame (16) and extend to the outside; the two sides of the inside of the heat dissipation cold frame (17) are provided with circulating cooling flow channels, and the heat dissipation fins (20) on the two sides extend to the inside of the circulating cooling flow channels on one side, and the two sides of the inside of the electromagnetic shielding frame (18) are fixedly provided with micro circulating pumps (24), and the water delivery ends of the micro circulating pumps (24) on the two sides are respectively communicated with the inside of the circulating cooling flow channels on the two sides.

5. The adaptive filter-based intraoperative neuromonitoring anti-jamming device of claim 4, wherein: The two sides of the inside of the monitor (3) are provided with circulating cooling pipes (25), and the two ends of the circulating cooling pipes (25) on the two sides extend to the two sides of the monitor (3), one end of the circulating cooling pipe (25) on the left side is communicated with the inside of the circulating cooling flow channel on the left side, and the other end is communicated with the water inlet end of the micro circulating pump (24) on the left side, one end of the circulating cooling pipe (25) on the right side is communicated with the inside of the circulating cooling flow channel on the right side, and the other end is communicated with the water inlet end of the micro circulating pump (24) on the right side.

6. The adaptive filter-based intraoperative neural monitor anti-jamming device of claim 4, wherein: The two sides of the anti-interference shell (1) are fixedly provided with heat dissipation guide frames (21), and the two heat dissipation guide frames (21) are provided with guide openings (22) on the side close to the anti-interference shell (1); one side of the heat dissipation fin (20) extends to the inside of the guide opening (22), and one side of the heat dissipation guide frame (21) is fixedly provided with an axial flow fan (23), and the blowing end of the axial flow fan (23) is communicated with the inside of the guide opening (22).

7. The adaptive filter-based intraoperative neural monitor anti-jamming device of claim 1, wherein: The positioning assembly (5) comprises a fixing frame (9) and a positioning frame (13), four fixing frames (9) are fixedly arranged around the inside of the anti-interference shell (1), and the four fixing frames (9) are located on the upper end surface of the shock-absorbing bottom pad (4); the inside of the fixing frame (9) is provided with an inflation cavity (10), and the top of the fixing frame (9) is sealingly provided with a sealing plate (12); the top of the sealing plate (12) is fixedly provided with an adjusting air pump (11), and the output end of the adjusting air pump (11) extends into the inside of the inflation cavity (10).

8. The adaptive filter-based intraoperative neural monitor anti-jamming device of claim 7, wherein: The side of the fixing frame (9) is movably provided with the positioning frame (13), the two sides of the positioning frame (13) are fixedly provided with adjusting springs (15), the inside of the adjusting spring (15) is further provided with a damper, and one end of the adjusting spring (15) is fixedly connected with the inside wall of the fixing frame (9); the two sides of the positioning frame (13) are fixedly provided with closed rubber sleeves (14), and one side of the two closed rubber sleeves (14) is fixedly connected with the side wall of the fixing frame (9).

9. The adaptive filter-based intraoperative neural monitor anti-jamming device of claim 1, wherein: The output end of the signal acquisition module is connected with the input end of the adaptive filtering processing module, the output end of the adaptive filtering processing module is connected with the input end of the signal output module, the power anti-interference module is electrically connected with each module and provides stable power supply, and the central control module is in communication connection with the signal acquisition module, the adaptive filtering processing module, the signal output module and the power anti-interference module, and is used for coordinating the work of each module.

10. The anti-interference method of intraoperative neuromonitoring based on adaptive filtering according to any one of claims 1-9, applied to the anti-interference device of intraoperative neuromonitoring based on adaptive filtering, characterized in that: The steps include the following: The anti-interference shell (1) is placed in a stable area through the bottom anti-skid supporting block (8), the monitor (3) is placed on the shock-absorbing bottom pad (4) after the closed cover plate (2) is removed, the adjusting air pump (11) of the positioning assembly (5) is started to inflate the inflation cavity (10), so that the positioning frame (13) is tightly attached to the side wall of the monitor (3) and a elastic allowance is reserved through the adjusting spring (15), and the closed cover plate (2) is closed to make the limiting top plate (6) cooperate with the limiting spring (7) to limit the monitor (3) in the longitudinal direction; The amplification multiple, the filter cutoff frequency of the signal acquisition module, the LMS algorithm parameters of the adaptive filtering processing module and the output voltage of the power anti-interference module are set through the central control module, and the line connection state of each module is checked; The miniature circulating pump (24) and the axial flow fan (23) form a heat dissipation loop, the neural electrical signal is collected through the shielded platinum electrode, is transmitted to the adaptive filtering processing module after differential amplification and pre-filtering to dynamically suppress interference, and is then transmitted to the monitor (3) by the RS485 driving chip after signal isolation and waveform shaping, and the central control module monitors the state of each module in real time and processes exceptions.

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