Mixing and stirring equipment for producing bismuth potassium citrate raw material medicine

Abstract

The invention relates to the technical field of mixing equipment, in particular to mixing and stirring equipment for producing a bismuth potassium citrate raw material medicine, which comprises a tank body, two liquid preparation components for preparing raw material liquid are arranged at the top of the tank body, and a mixing component for mixing prepared liquid is arranged on the tank body and below the liquid preparation components. A plurality of precipitation assemblies for concentrating and crystallizing a mixed solution are distributed in the tank body in the circumferential direction, a drying assembly is arranged below the precipitation assemblies in the tank body, the drying assembly comprises a drying tank, an evaporation cone, a blocking ring, a stirring rod and a grinding cone, and all the assemblies are matched with one another to complete production of a bismuth potassium citrate bulk drug; the technical effects of realizing a series of production processes from raw material liquid preparation, mixing, precipitation, drying and grinding and the like of the bismuth potassium citrate raw material medicine and improving the production efficiency and the product quality are achieved.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of mixing equipment, in particular to a mixing and stirring equipment for producing bismuth potassium citrate bulk drug. BACKGROUND

[0002] In the field of pharmaceutical production, the production quality and efficiency of bulk drugs have always been the focus of the industry. With the rapid development of the pharmaceutical industry, people's demand for drug quality and safety is becoming higher and higher, and the demand for bulk drugs such as bismuth potassium citrate, which is commonly used and important, is also increasing. As a widely used gastric mucosa protective agent, bismuth potassium citrate plays a key role in the treatment of digestive system diseases such as gastric ulcer and duodenal ulcer. The refinement, efficiency and stability of its production process not only relate to the quality and efficacy of the drug, but also have a profound impact on meeting the huge demand of the market and promoting the development of the entire pharmaceutical industry. Continuously exploring and improving the production equipment and process of bismuth potassium citrate can significantly improve its yield and purity, and inject new vitality into the development of the pharmaceutical industry.

[0003] In the past production process of bismuth potassium citrate bulk drug, the liquid preparation, mixing, precipitation, drying and grinding of the raw materials are usually operated by relatively dispersed equipment. For drying, the traditional and relatively simple method is usually used, that is, the hot air drying method, that is, the solid particles after precipitation are placed in the drying equipment, and the water is taken away by hot air circulation. This method relies on the contact between hot air and the surface of the material for heat transfer and water evaporation, and the drying speed is slow, and because of the uneven distribution of heat, it is easy to cause local overheating of the material, and then cause the agglomeration of the material.

[0004] The existing technology has obvious defects in the drying process of bismuth potassium citrate bulk drug. The traditional hot air drying method has low drying efficiency and is easy to cause material agglomeration, making the subsequent grinding process more difficult and affecting the uniformity and purity of the product; on the other hand, one equipment is used for each link, and the raw materials need to be transferred multiple times, so the process is more cumbersome. SUMMARY

[0005] In order to improve the drying efficiency and effect and the grinding efficiency, the present application provides a mixing and stirring equipment for producing bismuth potassium citrate bulk drug, which adopts the following technical scheme: A mixing and stirring equipment for producing bismuth potassium citrate bulk drug, comprising: a tank body; a liquid preparation assembly for preparing liquid for raw materials, the liquid preparation assembly being provided with two installation portions on the top of the tank body; a mixing assembly for mixing the liquid in the two liquid preparation assemblies, the mixing assembly being installed on the tank body below the two liquid preparation assemblies and being in communication with the liquid preparation assemblies through a connecting pipe; A plurality of precipitation assemblies for concentrating crystallization of liquid in the mixing assembly, each of the precipitation assemblies being in communication with the solution preparation assembly through a connecting pipe, and the plurality of precipitation assemblies being distributed in the tank body in a circumferential direction; A plurality of drying assemblies for drying and grinding the precipitated solid particles in the precipitation assemblies, the drying assembly comprising: A drying tank installed in the tank body and located below the precipitation assemblies, and the plurality of precipitation assemblies being in communication with the drying tank through connecting pipes; An evaporation cone with a conical head coaxially arranged in the drying tank and coaxially and rotatably connected to the drying tank, and a heating layer arranged below the conical surface of the evaporation cone; A plurality of blocking rings coaxially arranged on the surface of the evaporation cone and inclined upward away from the axis of the evaporation cone, the blocking rings being filter screens; the blocking rings and the surface of the evaporation cone form evaporation zones for accommodating the precipitated solids; and the plurality of blocking rings are arranged along the generatrix direction of the surface of the evaporation cone; A stirring rod fixed at one end to the drying tank and extending into the evaporation zone at the other end; and one stirring rod being arranged in each evaporation zone; A grinding cone arranged below the evaporation cone with a downward conical head, and a grinding ring disc arranged in the drying tank and cooperating with the grinding cone to grind the dried solid particles.

[0006] Further, the precipitation assembly further comprises: A liquid separation ring fixed to the top wall of the drying tank and coaxial with the evaporation cone; a cavity is formed in the interior of the liquid separation ring, and a plurality of liquid separation holes are formed in the bottom wall of the cavity along the axis of the evaporation cone; and the precipitation assembly is in communication with the inner cavity of the liquid separation ring through a connecting pipe.

[0007] Further, a collection groove is formed in the surface of the evaporation cone at the bottommost evaporation zone, and a filter screen is arranged on the surface of the collection groove.

[0008] Further, a metering assembly is further included; The solution preparation assembly comprises: A solution preparation tank embedded in the top of the tank body; A collection tank coaxially and rotatably connected to the solution preparation tank and open at the top end; a first rotating shaft coaxially fixed to the collection tank and extending upward out of the solution preparation tank; a helical blade coaxially arranged outside the collection tank; and a first channel formed in the inner wall of the solution preparation tank, one end of the first channel being in communication with the bottom of the solution preparation tank and the other end extending above the collection tank; An electromagnetic valve and a pH monitoring meter are arranged at the position where the first channel is in communication with the bottom of the solution preparation tank; The filter cage is detachably installed in the first channel; The metering assembly is installed on the liquid preparation tank and is used for quantitatively sucking the liquid in the first channel into the collecting tank.

[0009] Further, the metering assembly comprises: A piston disc is provided with a horizontal section on the first channel, the piston disc slides along the horizontal section, one side of the piston disc close to the liquid inlet of the first channel is provided with a one-way valve allowing liquid to flow to one side of the piston disc only, a liquid passage is formed on the piston disc, and a one-way valve allowing liquid to flow to one side of the piston disc close to the liquid outlet of the first channel only is installed on the liquid passage. A piston rod is connected to the piston disc, and the piston rod is slidingly connected to the liquid preparation tank along the direction of the horizontal section.

[0010] Further, the metering assembly further comprises: A driving disc is coaxially sleeved on the first rotating shaft and is coaxially and rotationally connected to the liquid preparation tank; the periphery of the driving disc is wavy, a first guide groove is formed on the peripheral wall of the driving disc along the peripheral direction, and the horizontal section is arranged along the meridian direction of the first rotating shaft; one end of the piston rod is fixed to the piston disc, and the other end is located in the first guide groove and reciprocates along the axial direction of the first rotating shaft with the rotation of the driving disc.

[0011] Further, the metering assembly further comprises: A mounting disc is coaxially sleeved on the first rotating shaft and is located above the collecting tank; A first driving member is fixed to the liquid preparation tank and is used for moving the mounting disc along the axial direction of the first rotating shaft; A fixing ring is coaxially and rotationally connected to the mounting disc, and the fixing ring is synchronously rotated with the first rotating shaft through a fixing member; A fixing rod is fixed to the fixing ring at one end and extends along the meridian direction of the fixing ring at the other end, an elastic slidingly connected movable rod is arranged on the fixing rod along the meridian direction of the fixing ring, and a contact switch is arranged on the fixing rod; A spiral guide rail is coaxially arranged on the side of the mounting disc facing the collecting tank and is located above the movable rod; one end of the spiral guide rail is connected with a guide rail; A guide strip is arranged on the driving disc along the meridian direction of the fixing ring, a second guide groove is formed in the top wall of the guide strip along the arrangement direction of the guide strip, and a limiting strip is arranged on each of the vertical two side walls of the second guide groove along the arrangement direction of the second guide groove. A limiting rod is elastically connected to the movable rod in the vertical direction away from the fixed ring; a limiting ring with the same diameter as the distance between the two vertical walls of the second guide groove is coaxially fixed on the limiting rod; the projection of the movable rod on the mounting disc is located in the internal blank of the vortex guide rail, and the movable rod abuts against the contact switch in the normal state; the top end of the limiting rod is located below the vortex guide rail in the normal state; A first and a second avoiding groove are formed on the limiting strip for the limiting ring to pass through the limiting strip; the second avoiding groove is located between the first rotating shaft and the first avoiding groove, and the second avoiding groove is located directly below the limiting rod when the movable rod is in the normal state; A wedge-shaped block is installed below the second avoiding groove to push the limiting ring moving from the first avoiding groove to the second avoiding groove above the guide strip; a third avoiding groove is formed on the side of the second avoiding groove close to the first avoiding groove to avoid the movement of the limiting ring; Two flip plates are rotationally connected to the end of the guide strip at the third avoiding groove, and a limiting block is arranged below the flip plate; a chamfer is arranged on the side of the bottom wall of the limiting ring; when the limiting ring moves above the limiting strip through the wedge-shaped block, the flip plate is flipped upwards; when the limiting ring moves from the second avoiding groove to the first avoiding groove, the chamfer of the limiting ring abuts against the top wall of the flip plate, and the limiting block limits the flip plate from flipping downwards.

[0012] Further, the fixing member comprises; An electromagnet is arranged in the installation groove in the inner wall of the fixed ring; A magnetic column is elastically and slidably connected in the two installation grooves in the first rotating shaft, and the magnetic column is located in the installation groove on the first rotating shaft in the normal state.

[0013] Further, the mixing assembly comprises: A mixing tank is coaxially arranged in the tank body and located below the liquid preparation tank; the collection tank and the mixing tank are connected through a connecting pipe, and an electromagnetic valve is arranged on the connecting pipe; A second rotating shaft is coaxially rotationally connected to the mixing tank through the top wall of the mixing tank; the second rotating shaft is provided with stirring blades on the section in the mixing tank.

[0014] Further, the precipitation assembly comprises: A precipitation tank is installed in the tank body and located below the mixing tank; the precipitation tank is in communication with the mixing tank through a connecting pipe, and an electromagnetic valve is arranged on the connecting pipe; a temperature control layer is arranged on the peripheral wall of the precipitation tank. A condensing pipe is provided outside the tank body, and a cooling box and a recovery box are provided outside the condensing pipe, one end of the condensing pipe is communicated with the top of the precipitation tank, and the other end penetrates through the cooling box and is communicated with the recovery box; A vacuum pump is installed on the condensing pipe to extract the gas in the precipitation tank.

[0015] Therefore, the application has at least one of the following beneficial technical effects: 1. The mixing and stirring device for producing bismuth potassium citrate bulk drug is designed, the liquid mixture with solid particles is blocked in the evaporation zone through the cooperation of the evaporation cone and the plurality of blocking rings, the surface of the evaporation cone is heated through the heating layer, and the solid particles in the evaporation zone are stirred through the stirring rod with the rotation of the evaporation cone; 2. The mixing and stirring device for producing bismuth potassium citrate bulk drug is designed, and the raw materials in the two liquid preparation tanks are accurately controlled to be added into the mixing tank through the metering assembly; 3. The mixing and stirring device for producing bismuth potassium citrate bulk drug is designed, and the precipitation assembly is used to accelerate the crystallization process. BRIEF DESCRIPTION OF DRAWINGS

[0016] Figure 1 It is a whole structure schematic diagram of the mixing and stirring device for producing bismuth potassium citrate bulk drug according to the embodiment of the application; Figure 2 It is a whole structure schematic diagram of the mixing and stirring device for producing bismuth potassium citrate bulk drug according to the embodiment of the application; Figure 3 It is a partial structure schematic diagram of the mixing and stirring device for producing bismuth potassium citrate bulk drug according to the embodiment of the application, which aims to show the liquid preparation assembly; Figure 4 It is a partial structure schematic diagram of the mixing and stirring device for producing bismuth potassium citrate bulk drug according to the embodiment of the application, which aims to show the metering assembly; Figure 5 It is a partial structure schematic diagram of the mixing and stirring device for producing bismuth potassium citrate bulk drug according to the embodiment of the application, which aims to show the metering assembly; Figure 6 It is Figure 5 A enlarged schematic diagram of A part of the mixing and stirring device for producing bismuth potassium citrate bulk drug according to the embodiment of the application; Figure 7 It is a partial structure schematic diagram of the mixing and stirring device for producing bismuth potassium citrate bulk drug according to the embodiment of the application, which aims to show the guide bar structure; Figure 8 It is a partial structure schematic diagram of the mixing and stirring device for producing bismuth potassium citrate bulk drug according to the embodiment of the application, which aims to show the mixing assembly; Figure 9is a partial structural schematic diagram of a mixing and stirring device for producing potassium bismuth citrate bulk drug, aiming to show the precipitation assembly; Figure 10 is a partial structural schematic diagram of a mixing and stirring device for producing potassium bismuth citrate bulk drug, aiming to show the drying assembly.

[0017] Fig. 1 is a tank body; Fig. 2 is a liquid preparation assembly; Fig. 21 is a liquid preparation tank; Fig. 211 is a first channel; Fig. 22 is a collection tank; Fig. 23 is a first rotating shaft; Fig. 24 is a PH monitoring meter; Fig. 25 is a filter cage; Fig. 3 is a mixing assembly; Fig. 31 is a mixing tank; Fig. 32 is a second rotating shaft; Fig. 4 is a precipitation assembly; Fig. 41 is a precipitation tank; Fig. 42 is a condenser tube; Fig. 43 is a vacuum pump; Fig. 44 is a temperature control layer; Fig. 45 is a cooling box; Fig. 46 is a recovery box; Fig. 5 is a drying assembly; Fig. 51 is a drying tank; Fig. 52 is an evaporation cone; Fig. 53 is a blocking ring; Fig. 531 is an evaporation zone; Fig. 54 is a stirring rod; Fig. 55 is a grinding cone; Fig. 56 is a grinding ring disc; Fig. 57 is a liquid separation ring; Fig. 58 is a collection groove; Fig. 6 is a metering assembly; Fig. 61 is a piston disc; Fig. 611 is a piston rod; Fig. 612 is a one-way valve; Fig. 62 is a driving disc; Fig. 621 is a first guide groove; Fig. 63 is a mounting disc; Fig. 631 is a first driving member; Fig. 632 is a fixing ring; Fig. 633 is a fixing member; Fig. 6331 is an electromagnet; Fig. 6332 is a magnetic column; Fig. 64 is a fixing rod; Fig. 641 is a movable rod; Fig. 642 is a contact switch; Fig. 65 is a vortex guide rail; Fig. 651 is a guide rail; Fig. 66 is a guide strip; Fig. 661 is a wedge-shaped block; Fig. 662 is a turnover plate; Fig. 663 is a second guide groove; Fig. 664 is a limiting strip; Fig. 665 is a first avoiding groove; Fig. 666 is a second avoiding groove; Fig. 667 is a third avoiding groove; Fig. 668 is a limiting block; Fig. 67 is a limiting rod; Fig. 671 is a limiting ring. DETAILED DESCRIPTION

[0018] The following will be described in detail below with reference to the accompanying drawings Figures 1-10 The application will be further described in detail.

[0019] The application discloses a mixing and stirring device for producing potassium bismuth citrate bulk drug.

[0020] Reference will be made to Figure 1 and Figure 2 The mixing and stirring device for producing potassium bismuth citrate bulk drug comprises a tank body 1 and a liquid preparation assembly 2, a mixing assembly 3, a precipitation assembly 4 and a drying assembly 5 installed on the tank body 1, wherein the liquid preparation assembly 2 is provided with two embedded tanks on the top of the tank body 1, the precipitation assembly 4 is provided with a plurality of circumferentially distributed tanks along the tank body 1; In this way, personnel first add bismuth nitrate and dilute nitric acid in a liquid preparation assembly 2 to obtain a bismuth nitrate solution, and then prepare a potassium citrate solution in another liquid preparation assembly 2. After the two solutions are prepared, the two solutions are added to a mixing assembly 3 in a proportion for reaction. After the reaction is completed, the solution in the mixing assembly 3 is added to a precipitation assembly 4 for concentration. After the concentration is completed, anhydrous ethanol is added for crystallization. The solid crystals are added to a drying assembly 5 for drying and grinding, and then a bismuth potassium citrate solid powder is obtained.

[0021] With reference to Figure 2 and Figure 3 , the mixing and stirring device further comprises a metering assembly 6. The liquid preparation assembly 2 comprises a liquid preparation tank 21 and a collection tank 22. The liquid preparation tank 21 is embedded at the top of the tank body 1 and is provided with a feeding opening. The collection tank 22 is coaxially connected to the liquid preparation tank 21 and is open at the top. The collection tank 22 is coaxially fixed with a first rotating shaft 23 which extends upwardly out of the liquid preparation tank 21. In the present application, the first rotating shaft 23 is driven to rotate by a motor. A spiral blade is coaxially arranged outside the collection tank 22 and has a spacing from the side wall of the liquid preparation tank 21. A first channel 211 is formed in the inner wall of the liquid preparation tank 21 and is in communication with the bottom of the liquid preparation tank 21 at one end and extends above the collection tank 22 at the other end. An electromagnetic valve and a PH monitor 24 are arranged at the position where the first channel 211 is in communication with the bottom of the liquid preparation tank 21. A filter cage 25 is detachably arranged in the first channel 211. In the present application, the first channel 211 is provided with a vertical section which is in communication with the outside and is provided with a sealing plug at the communication position. The filter cage 25 is arranged in the vertical section and is clamped. The metering assembly 6 is arranged on the liquid preparation tank 21 and is used to quantitatively suck the liquid in the first channel 211 into the collection tank 22. In this way, the personnel add the solution composition to be prepared into the collection tank 22. Then the motor drives the collection tank 22 to rotate, and the spiral blade on the outer wall of the collection tank 22 drives the materials in the liquid preparation tank 21 to mix. After the PH value measured by the PH monitor 24 remains stable and meets the required value, the electromagnetic valve at the position where the first channel 211 is in communication with the liquid preparation tank 21 is opened. At this time, the metering assembly 6 starts to work and quantitatively sucks the liquid in the first channel 211 into the collection tank 22 after the liquid is filtered by the filter cage 25 for collection. The filter cage 25 is regularly replaced in a detachable manner, and the liquid preparation tank 21 is cleaned.

[0022] With reference to Figure 3 and Figure 4The metering assembly 6 comprises a piston disc 61 and a piston rod 611. The first channel 211 is provided with a horizontal section. The piston disc 61 slides along the horizontal section. The piston disc 61 is provided with a one-way valve 612 on the side close to the liquid inlet of the first channel 211. The piston disc 61 is provided with a liquid passage. The liquid passage is provided with a one-way valve 612 on the side close to the liquid outlet of the first channel 211. The piston rod 611 is connected to the piston disc 61 and slides along the horizontal section and is connected to the liquid preparation tank 21. In this way, the piston rod 611 is controlled to slide and drive the piston disc 61 to move. The liquid in the liquid preparation tank 21 is drawn into the collecting tank 22 through the one-way valve 612. The reciprocating stroke and reciprocating times of the piston rod 611 are controlled to control the amount of liquid drawn into the collecting tank 22.

[0023] Referring to Figure 3 and Figure 4 , in order to increase the speed of extraction, the first channel 211 is provided with four channels, which are evenly distributed along the circumference of the liquid preparation tank 21. Each channel is provided with a piston disc 61 and a piston rod 611.

[0024] Referring to Figure 3 and Figure 4 , in order to simultaneously drive the four piston discs 61 to move simultaneously, the metering assembly 6 further comprises a driving disc 62. The driving disc 62 is coaxially sleeved on the first rotating shaft 23 and is coaxially and rotatably connected to the liquid preparation tank 21. The periphery of the driving disc 62 is wavy, like a flower. The driving disc 62 is provided with a first guide groove 621 along the circumferential direction of the driving disc 62. The horizontal section is arranged along the meridian direction of the first rotating shaft 23. One end of the piston rod 611 is fixed to the piston disc 61, and the other end is located in the second guide groove 663 and rotates with the driving disc 62. The piston disc 61 reciprocates towards the axis of the first rotating shaft 23. In this way, the first guide groove 621 pulls the plurality of piston rods 611 to reciprocate along the meridian direction of the first rotating shaft 23 by rotating the driving disc 62.

[0025] Referring to Figure 4 , Figure 5 , Figure 6 and Figure 7, in order to control the rotation of the driving disc 62 and the reciprocating times of the piston rod 611 after the liquid in the liquid preparation tank 21 meets the standard, the metering assembly 6 further comprises a mounting disc 63, a first driving member 631, a fixed ring 632, a fixed rod 64, a movable rod 641, a spiral guide rail 65, a guide strip 66, a limiting rod 67, a wedge block 661 and a turnover plate 662. The mounting disc 63 is coaxially sleeved on the first rotating shaft 23 and located above the collecting tank 22. The first driving member 631 is fixed on the liquid preparation tank 21 and used to drive the mounting disc 63 to move along the axial direction of the first rotating shaft 23. In the application, the first driving member 631 is a pneumatic cylinder. The fixed ring 632 is coaxially and rotatably connected to the mounting disc 63, and the fixed ring 632 is synchronously rotated with the first rotating shaft 23 through a fixing member 633. One end of the fixed rod 64 is fixed to the fixed ring 632, and the other end extends along the meridian direction of the fixed ring 632. The movable rod 641 is elastically and slidably connected to the fixed rod 64 along the meridian direction of the fixed ring 632. The fixed rod 64 is provided with a contact switch 642. The spiral guide rail 65 is coaxially arranged on one side of the mounting disc 63 facing the collecting tank 22 and located above the movable rod 641. One end of the spiral guide rail 65 is connected with a guide rail 651. The guide strip 66 is arranged on the driving disc 62 along the meridian direction of the fixed ring 632. A second guide groove 663 is formed through the top wall of the guide strip 66 along the arrangement direction thereof. Two limiting strips 664 are arranged on the vertical two side walls of the second guide groove 663 along the arrangement direction thereof. The limiting rod 67 is elastically and slidably connected to the end of the movable rod 641 away from the fixed ring 632 along the vertical direction. The limiting ring 671 with a diameter equal to the distance between the vertical two side walls of the second guide groove 663 is coaxially fixed on the limiting rod 67. In the normal state, the projection of the movable rod 641 on the mounting disc 63 is located in the blank space inside the spiral guide rail 65, and the movable rod 641 abuts against the contact switch 642. In the normal state, the top end of the limiting rod 67 is located below the spiral guide rail 65. The limiting strips 664 are provided with a first avoiding groove 665 and a second avoiding groove 666 for the limiting ring 671 to pass through the limiting strips 664. The second avoiding groove 666 is located between the first avoiding groove 665 and the first rotating shaft 23, and the second avoiding groove 666 is located directly below the limiting rod 67 when the movable rod 641 is in the normal state. The wedge block 661 is installed below the second avoiding groove 666 and used to push the limiting ring 671 moving from the first avoiding groove 665 to the second avoiding groove 666 to above the guide strip 66. The third avoiding groove 667 is formed on one side of the second avoiding groove 666 close to the first avoiding groove 665 for avoiding the movement of the limiting ring 671. The turnover plate 662 is rotationally connected to the end of the guide strip 66 at the third avoiding slot 667, and a limiting block 668 is arranged below the turnover plate 662; the bottom wall side of the limiting ring 671 is provided with a chamfer; when the limiting ring 671 moves to above the limiting strip 664 through the wedge-shaped block 661, the turnover plate 662 is turned upward; when the limiting ring 671 moves from the second avoiding slot 666 to the first avoiding slot 665, the chamfer of the limiting ring 671 abuts against the top wall of the turnover plate 662, and the limiting block 668 limits the turnover plate 662 from turning downward; Firstly, after the liquid in the liquid preparation tank 21 meets the standard monitored by the PH monitor 24, the data is fed back to the processor, the processor controls the first driving member 631 to drive the installation disc 63 to move downward through the controller, the installation disc drives the fixed ring 632 to move downward, the bottom end of the limiting rod 67 penetrates through the second avoiding slot 666 and abuts against the top end of the wedge-shaped block 661, at this time, the bottom wall of the limiting ring 671 is flush with the top wall of the limiting strip 664, and the side wall of the limiting ring 671 abuts against the vertical two side walls of the second guide slot 663, and the top end of the limiting rod 67 is located between the bottom wall of the vortex guide rail 65 and the installation disc at this time; Subsequently, the fixed ring 632 moves synchronously with the first rotating shaft 23 through the fixing member 633, and drives the fixed rod 64 to start rotating, at this time, the limiting rod 67 slides into the vortex guide rail 65 due to the abutment between the guide rail 651 and the limiting rod 67, and at the same time, the limiting rod 67 starts to move away from the first rotating shaft 23, and at the same time, the limiting ring 671 drives the guide strip 66 to rotate, the guide strip 66 drives the driving disc 62 to rotate, and due to the abutment between the chamfer of the bottom wall of the limiting ring 671 and the turnover plate 662, the turnover plate 662 cannot rotate due to the limitation of the limiting block 668, thereby the limiting ring 671 is always located above the limiting strip 664 in the process of moving away from the first rotating shaft 23, and the top end of the limiting rod 67 is always in abutment with the vortex guide rail 65; Subsequently, when the fixed ring 632 drives the driving disc 62 to rotate for a certain number of turns, the limiting ring 671 moves below the limiting strip 664 due to the elasticity of the limiting rod 67, and the top end of the limiting rod 67 moves below the vortex guide rail 65, and then under the elasticity of the movable rod 641, the limiting rod 67 starts to move toward the first rotating shaft 23, when it moves to the wedge-shaped block 661, the limiting ring 671 moves upward and pushes the turnover plate 662 to rotate, until the limiting rod 67 moves to the top end of the wedge-shaped block 661, and the turnover plate 662 naturally falls to the initial state, the movable rod 641 is in a normal state and is in abutment with the contact switch 642; At this time, if the extracted dose is sufficient, the contact switch 642 controls the fixing member 633 to make the fixed ring 632 disengage from the first rotating shaft 23, the installation disc moves upward driven by the first driving member 631, and the driving disc 62 stops rotating; if it is needed to continue to extract, the contact switch 642 is set to start the fixing member 633 and the first driving member 631 according to the contact number.

[0026] When it is needed to change the reciprocating times of the piston rod 611 in a single stroke of the active rod 641, a plurality of guide bars 66 can be made, the position of the first avoiding groove 665 is changed, and then the reciprocating times of the piston rod 611 in a single stroke are controlled.

[0027] Referring to Figure 5 In the present application, in order to better control the synchronous rotation or disengagement of the fixed ring 632 and the first rotating shaft 23, the fixing member 633 includes an electromagnet 6331 and a magnetic column 6332, and the inner wall of the fixed ring 632 is provided with a mounting groove, and the electromagnet 6331 is located in the mounting groove; the first rotating shaft 23 is provided with a mounting groove, and the magnetic column 6332 is elastically and slidingly connected in the two mounting grooves, and the magnetic column 6332 is located in the mounting groove on the first rotating shaft 23 in a normal state, and in order to facilitate the insertion of the magnetic column 6332 into the mounting groove on the fixed ring 632, the end of the magnetic column 6332 close to the electromagnet 6331 is provided with a chamfer.

[0028] Referring to Figure 2 and Figure 8 The mixing assembly 3 includes a mixing tank 31 and a second rotating shaft 32, the mixing tank 31 is coaxially arranged in the tank body 1 and located below the liquid preparation tank 21, the collecting tank 22 and the mixing tank 31 are connected through a connecting pipe, and the connecting pipe is provided with a solenoid valve; the second rotating shaft 32 is coaxially and rotationally connected to the mixing tank 31 through the top wall of the mixing tank 31, and the section of the second rotating shaft 32 located in the mixing tank 31 is provided with stirring blades, and in the present application, the second rotating shaft 32 is driven to rotate by a motor; After the liquid in the two collecting tanks 22 is collected enough, the solenoid valve is opened, the liquid in the collecting tank 22 flows into the mixing tank 31, and the motor drives the second rotating shaft 32 to rotate, and the two mixtures are mixed by the stirring blades.

[0029] Referring to Figure 1 , Figure 2 and Figure 9 The precipitation assembly 4 includes a precipitation tank 41, a condenser pipe 42 and a vacuum pump 43, the precipitation tank 41 is installed in the tank body 1 and located below the mixing tank 31, the precipitation tank 41 is communicated with the mixing tank 31 through a connecting pipe, and the connecting pipe is provided with a solenoid valve; the precipitation tank 41 is provided with a temperature control layer 44 on the peripheral wall; the precipitation tank 41 is provided with a feeding port; The tank body 1 is provided with a cooling box 45 and a recovery box 46 on the outside, one end of the condenser pipe 42 is communicated with the top of the precipitation tank 41, and the other end passes through the cooling box 45 and is communicated with the recovery box 46; The vacuum pump 43 is installed on the condenser pipe 42 and used for extracting the gas in the precipitation tank 41; In order to facilitate the subsequent collection of the precipitated crystals, the bottom of the precipitation tank 41 is conical; In this way, an electromagnetic valve is opened, the liquid in the mixing tank 31 flows into a sedimentation tank 41 through a connecting pipe, then the electromagnetic valve is closed, the vacuum pump 43 is started, the air pressure in the sedimentation tank 41 is lower than the standard atmospheric pressure, the boiling point temperature of the mixed liquid is reduced, the degradation of bismuth potassium citrate is prevented, the temperature control layer 44 controls the temperature in the sedimentation tank 41 to be between 40-55℃, the concentration is carried out, the gas in the condenser pipe 42 is condensed in the cooling box 45 and flows into the recovery box 46 for recovery; after the concentration is completed, the temperature is lowered, and the concentrated liquid is induced to crystallize by adding anhydrous ethanol, and is precipitated in the conical area.

[0030] With reference to Figure 2 and Figure 10 , the drying assembly 5 includes a drying tank 51, an evaporation cone 52, a blocking ring 53, a stirring rod 54, and a grinding cone 55, the drying tank 51 is installed in the tank body 1 and located below the sedimentation assembly 4, a plurality of conical bottoms of the sedimentation tanks 41 are communicated with the drying tank 51 through connecting pipes, and electromagnetic valves are arranged on the connecting pipes; The evaporation cone 52 is coaxially arranged in the drying tank 51 with the cone head upward and is coaxially connected with the drying tank 51, and in the present application, the evaporation cone 52 is driven to rotate by a motor; there is a gap between the evaporation cone 52 and the side wall of the drying tank 51, and a heating layer is arranged below the evaporation surface of the evaporation cone 52; a plurality of blocking rings 53 are arranged, the blocking rings 53 are coaxially arranged on the surface of the evaporation cone 52 and are arranged upwardly and obliquely away from the axis of the evaporation cone 52, and the blocking rings 53 are filter screens; the blocking rings 53 and the surface of the evaporation cone 52 form evaporation areas 531 for fixing the precipitates; a plurality of blocking rings 53 are arranged along the generatrix direction of the surface of the evaporation cone 52; The stirring rod 54 is fixed at one end with the drying tank 51 and extends to the evaporation area 531 at the other end; each evaporation area 531 is provided with one stirring rod 54; in the present application, the stirring rod 54 is provided with a plurality of branches at the end located in the evaporation area 531, so as to better stir the substances in the evaporation area 531; The evaporation cone 52 is provided with a grinding cone 55 below with the cone head downward, and the drying tank 51 is provided with a grinding ring disc 56 for grinding the fixed particles after drying in cooperation with the grinding cone 55; In this way, after the crystal precipitates in one sedimentation tank 41 for a sufficient time, the electromagnetic valve is opened, the crystal and the liquid mixture in the sedimentation tank 41 fall into the evaporation cone 52 through the connecting pipe, are intercepted and filtered by the plurality of blocking rings 53, the solid particles are retained in the evaporation area 531, and the liquid flows into the gap between the grinding cone 55 and the grinding ring disc 56 from the gap between the evaporation cone 52 and the drying tank 51, and then flows out from the bottom of the drying tank 51; The heating layer starts to heat the surface of the evaporation cone 52, at the same time, the evaporation cone 52 starts to rotate, and the setting of the stirring rod 54 not only turns the solid particles to accelerate the drying, but also avoids the solid particles from being combined into large blocks; When the drying is finished, the evaporation cone 52 is accelerated to rotate at a high speed, and the solid particles are thrown out from the evaporation area 531 by centrifugal force, and then enter the gap between the grinding cone 55 and the grinding ring disc 56 for grinding, and the ground powder falls from the middle area of the grinding ring disc 56; In order to better increase the drying efficiency, the volume of the mixture of the solid particles and the liquid in the precipitation tank 41 and the volume of the supernatant are obtained through multiple experiments, and then the electromagnetic valve opening time is controlled to evaporate only the liquid mixture with solid particles, and the rest of the supernatant can be directly discharged.

[0031] With reference to Figure 10 In order to better intercept the solid particles by the blocking ring 53, the precipitation assembly 4 further comprises a liquid distribution ring 57, which is fixed to the inner top wall of the drying tank 51 and coaxial with the evaporation cone 52; the liquid distribution ring 57 is internally provided with a cavity, and a plurality of liquid distribution holes are formed in the bottom wall of the cavity along the axis of the evaporation cone 52; the precipitation assembly 4 is communicated with the inner cavity of the liquid distribution ring 57 through a connecting pipe; In this way, the liquid mixture with solid particles first enters the liquid distribution ring 57, and then uniformly flows to the surface of the evaporation cone 52 through the plurality of liquid distribution holes, so that the solid particles in the evaporation area 531 are uniformly distributed.

[0032] With reference to Figure 10 In order to avoid interference caused by the liquid flowing through the grinding cone 55 and the grinding ring disc 56, a collection groove 58 is formed on the surface of the evaporation cone 52 at the bottom of the evaporation area 531, and a filter screen is arranged on the surface of the collection groove 58; a connecting pipe is arranged on the bottom of the collection groove 58 and penetrates through the bottom of the grinding cone 55; In this way, the liquid on the surface of the evaporation cone 52 flows into the collection groove 58 and flows out from the connecting pipe at the bottom of the collection groove 58.

[0033] The above are preferred embodiments of the present application, and do not limit the protection scope of the present application, therefore: any equivalent changes made on the structure, shape, principle of the present application should be covered within the protection scope of the present application.

Claims

1. A mixing and stirring device for producing bismuth potassium citrate raw material, characterized in that, include: Tank body (1); A liquid preparation assembly (2) for preparing raw materials into a liquid, wherein the liquid preparation assembly (2) has two components installed on the top of the tank body (1); The liquids in the two liquid preparation components (2) are mixed by a mixing component (3), which is installed on the tank (1), located below the two liquid preparation components (2), and connected to the liquid preparation components (2) through a connecting pipe; A precipitation assembly (4) for concentrating and crystallizing the liquid in the mixing assembly (3), wherein there are multiple precipitation assemblies (4), each of which is connected to the liquid dispensing assembly (2) through a connecting pipe, and the multiple precipitation assemblies (4) are distributed in the tank (1) circumferentially; A drying assembly (5) for drying and grinding the solid particles precipitated in the precipitation assembly (4), the drying assembly (5) comprising: A drying tank (51) is installed inside the tank body (1) and located below the sedimentation components (4). Multiple sedimentation components (4) are connected to the drying tank (51) through connecting pipes. An evaporating cone (52) is coaxially disposed inside the drying tank (51) with its cone head facing upwards, and is coaxially rotatably connected to the drying tank (51). A heating layer is provided below the cone surface of the evaporating cone (52). Multiple barrier rings (53) are coaxially disposed on the surface of the evaporation cone (52) and inclined upward along a direction away from the axis of the evaporation cone (52). The barrier rings (53) are filter screens. The barrier rings (53) and the surface of the evaporation cone (52) form an evaporation zone (531) for accommodating fixed precipitates. The multiple barrier rings (53) are disposed along the generatrix direction of the surface of the evaporation cone (52). A stirring rod (54) is provided, with one end fixed to the drying tank (51) and the other end extending into the evaporation zone (531); each evaporation zone (531) is provided with a stirring rod (54). A grinding cone (55) is provided below the evaporation cone (52), with the cone head facing downwards. A grinding ring disc (56) is provided inside the drying tank (51) to grind the fixed particles after drying in conjunction with the grinding cone (55).

2. The mixing and stirring equipment for producing bismuth potassium citrate raw material according to claim 1, characterized in that, The precipitation component (4) also includes: The liquid separating ring (57) is fixed to the inner top wall of the drying tank (51) and is coaxial with the evaporation cone (52); the liquid separating ring (57) has a cavity inside, and the bottom wall of the cavity has multiple liquid separating holes along the axis of the evaporation cone (52); the precipitation component (4) is connected to the inner cavity of the liquid separating ring (57) through a connecting pipe.

3. The mixing and stirring equipment for producing bismuth potassium citrate raw material according to claim 1, characterized in that, The surface of the evaporation cone (52) has a collection tank (58) in the bottom evaporation zone (531), and the surface of the collection tank (58) is provided with a filter screen.

4. A mixing and stirring apparatus for producing bismuth potassium citrate raw material according to any one of claims 1-3, characterized in that, It also includes a metering component (6); The solution preparation assembly (2) includes: A liquid preparation tank (21) is embedded in the top of the tank body (1); A collection tank (22) is coaxially rotatably connected inside the liquid preparation tank (21) and has an open top. A first rotating shaft (23) is coaxially fixed to the collection tank (22) and extends upward to the outside of the liquid preparation tank (21). Spiral blades are coaxially provided on the outside of the collection tank (22). A first channel (211) is provided on the inner wall of the liquid preparation tank (21), one end of which is connected to the bottom of the liquid preparation tank (21) and the other end extends to the top of the collection tank (22). A solenoid valve and a pH meter (24) are provided at the connection between the first channel (211) and the bottom of the liquid preparation tank (21); A filter cage (25) is detachably installed in the first channel (211); The metering component (6) is installed on the liquid mixing tank (21) and is used to quantitatively draw the liquid in the first channel (211) into the collection tank (22).

5. A mixing and stirring device for producing bismuth potassium citrate raw material according to claim 4, characterized in that, The metering component (6) includes: A piston disc (61) is provided with a horizontal section on the first channel (211). The piston disc (61) slides along the horizontal section. A one-way valve (612) is provided on the side of the piston disc (61) near the liquid inlet of the first channel (211) to allow liquid to flow to the side of the piston disc (61) only. A liquid passage hole is provided on the piston disc (61). A one-way valve (612) is installed on the liquid passage hole to allow liquid to flow to the side of the piston disc (61) near the liquid outlet of the first channel (211) only. A piston rod (611) is connected to the piston disc (61), and the piston rod (611) is slidably connected to the liquid preparation tank (21) along the direction of the horizontal section.

6. The mixing and stirring equipment for producing bismuth potassium citrate raw material according to claim 5, characterized in that, The metering component (6) also includes: A drive disk (62) is coaxially mounted on the first rotating shaft (23) and coaxially rotatably connected to the liquid preparation tank (21). The drive disk (62) has a wavy periphery, and a first guide groove (621) is provided on the peripheral wall of the drive disk (62) along its circumferential direction. The horizontal section is arranged along the meridian direction of the first rotating shaft (23). One end of the piston rod (611) is fixed to the piston disk (61), and the other end is located in the first guide groove (621). As the drive disk (62) rotates, the piston disk (61) reciprocates toward the axis of the first rotating shaft (23).

7. A mixing and stirring device for producing bismuth potassium citrate raw material according to claim 6, characterized in that, The metering component (6) also includes: The mounting disc (63) is coaxially sleeved on the first rotating shaft (23) and located above the collection tank (22); The first driving component (631) is fixed on the liquid mixing tank (21) and is used to drive the mounting disc (63) to move along the axis of the first rotating shaft (23); A fixing ring (632) is coaxially rotatably connected to the mounting disc (63), and the fixing ring (632) rotates synchronously with the first rotating shaft (23) through a fixing member (633); A fixed rod (64) is provided, one end of which is fixed to the fixed ring (632), and the other end extends along the meridian direction of the fixed ring (632). A movable rod (641) is elastically slidably connected to the fixed rod (64) along the meridian direction of the fixed ring (632). A contact switch (642) is provided on the fixed rod (64). A vortex guide rail (65) is coaxially disposed on the side of the mounting disc (63) facing the collection tank (22) and located above the movable rod (641); a guide rail (651) is connected to one end of the vortex guide rail (65); A guide bar (66) is disposed on the drive disc (62) along the meridian direction of the fixed ring (632). A second guide groove (663) is provided through the top wall of the guide bar (66) along its setting direction. A limiting bar (664) is provided on each of the two vertical side walls of the second guide groove (663) along its opening direction. A limiting rod (67) is elastically slidably connected to the end of the movable rod (641) away from the fixed ring (632) in the vertical direction; a limiting ring (671) with a diameter equal to the distance between the two vertical side walls of the second guide groove (663) is coaxially fixed on the limiting rod (67); when the movable rod (641) is in its normal state, the projection of the movable rod (641) on the mounting disk (63) is located in the blank space inside the vortex guide rail (65), and the movable rod (641) abuts against the contact switch (642); when the limiting rod (67) is in its normal state, the top end of the limiting rod (67) is located below the vortex guide rail (65); The limiting strip (664) has a first clearance groove (665) and a second clearance groove (666) for the limiting ring (671) to pass through the limiting strip (664); the second clearance groove (666) is located between the first rotating shaft (23) and the first clearance groove (665), and the second clearance groove (666) is located directly below the limiting rod (67) when the movable rod (641) is in its normal state; A wedge block (661) is installed below the second clearance groove (666) to push the limiting ring (671) that moves from the first clearance groove (665) to the second clearance groove (666) above the guide bar (66); a third clearance groove (667) is provided on the side of the second clearance groove (666) near the first clearance groove (665) to allow the limiting ring (671) to move. Two flip plates (662) are rotatably connected to the end of the guide strip (66) at the third clearance groove (667). A limit block (668) is provided below the flip plate (662). The bottom wall side of the limit ring (671) is chamfered. When the limit ring (671) moves above the limit strip (664) via the wedge block (661), the flip plate (662) flips upward. When the limit ring (671) moves from the second clearance groove (666) to the first clearance groove (665), the chamfer of the limit ring (671) abuts against the top wall of the flip plate (662), and the limit block (668) restricts the flip plate (662) from flipping downward.

8. A mixing and stirring device for producing bismuth potassium citrate raw material according to claim 7, characterized in that, The fastener (633) includes; An electromagnet (6331) is provided with an installation groove on the inner wall of the fixing ring (632), and the electromagnet (6331) is located in the installation groove; The magnetic column (6332) has an installation groove in the first rotating shaft (23). The magnetic column (6332) is elastically slidably connected to the two installation grooves. When the magnetic column (6332) is in normal state, it is located in the installation groove on the first rotating shaft (23).

9. A mixing and stirring device for producing bismuth potassium citrate raw material according to claim 8, characterized in that, The hybrid component (3) includes: A mixing tank (31) is coaxially disposed inside the tank body (1) and located below the liquid preparation tank (21). The collection tank (22) is connected to the mixing tank (31) via a connecting pipe, and a solenoid valve is provided on the connecting pipe. The second rotating shaft (32) passes through the top wall of the mixing tank (31) and is coaxially rotatably connected to the mixing tank (31). The section of the second rotating shaft (32) located inside the mixing tank (31) is provided with stirring blades.

10. A mixing and stirring device for producing bismuth potassium citrate raw material according to claim 9, characterized in that, The precipitation component (4) includes: A sedimentation tank (41) is installed inside the tank body (1) and located below the mixing tank (31). The sedimentation tank (41) is connected to the mixing tank (31) through a connecting pipe, and a solenoid valve is provided on the connecting pipe. A temperature control layer (44) is provided on the periphery of the sedimentation tank (41). A condenser (42) is provided on the outside of the tank body (1), a cooling box (45) and a recovery box (46) are provided. One end of the condenser (42) is connected to the top of the sedimentation tank (41), and the other end passes through the cooling box (45) and is connected to the recovery box (46). A vacuum pump (43) is installed on the condenser tube (42) and is used to extract gas from the sedimentation tank (41).

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