Large volume wearable drug delivery device

Abstract

Provided herein is a wearable drug delivery device comprising: a housing having a perimeter and defining an interior, the housing having a first port and a second port disposed on an outer surface thereof; a needle movable between a first position in which the needle is fully received within the interior of the housing and a second position in which at least a portion of the needle extends through the first port; a button disposed on an outer surface of the housing, the button configured to move the needle from the first position to the second position; a cannula disposed around an exterior of the needle; a pump received within the interior of the housing, the pump being in fluid communication with the sleeve; and a reservoir disposed outside the interior of the housing and offset from the perimeter of the housing, the reservoir in fluid communication with the second port and the pump.

Description

Cross-references to related applications

[0001] This application claims priority to U.S. Provisional Application No. 63 / 535,096, entitled “Large-Volume Wearable Drug Delivery Device,” filed August 29, 2023, the disclosure of which is incorporated herein by reference in its entirety. Background of the Invention Field of the Invention This disclosure generally relates to wearable drug delivery devices, and more particularly to wearable drug delivery devices having a large-capacity reservoir and features that improve patient comfort and safety when worn.

[0002] Description of related technologies Various types of automated infusion devices or drug delivery systems have been developed to allow medication solutions and other liquid therapeutic preparations to be administered by healthcare professionals or self-injected. Typically, these devices include a reservoir pre-filled with the liquid therapeutic preparation and some type of automated needle injection mechanism that can be triggered by the user. When the volume of the fluid or drug to be administered is typically less than a certain volume (e.g., 1 mL), an autoinjector is usually used, with an injection time typically around 10 to 15 seconds. When the volume of the fluid or drug to be administered exceeds 1 mL and / or the liquid is sufficiently viscous, the injection time typically becomes longer, making it difficult for the patient to maintain compliance and contact between the device and the target area of ​​the patient's skin. Furthermore, as the volume of the drug to be administered becomes larger, a longer injection time is desired. The traditional method for slowly injecting medication into a patient is to initiate an IV and slowly inject the medication into the patient. This procedure is typically performed in a hospital or outpatient setting.

[0003] Conventional autoinjectors are limited in the amount of drug composition that can be delivered to a patient due to the size limitations of the syringe itself. Typically, it is desirable for autoinjectors to be worn discretely, thus providing only limited space for storing the drug composition. Furthermore, autoinjectors are usually attached to the patient's skin via adhesive pads, which limits the weight of the drug composition that can be safely carried without the risk of separation. Therefore, there is a need in the art for wearable devices that have a larger reservoir and features that increase patient compliance and allow for more secure adhesion to the patient. Summary of the Invention

[0004] This document provides a wearable drug delivery device comprising: a housing having a periphery and defining an interior, the housing having a first port and a second port disposed on its outer surface; an adhesive pad disposed on the outer surface of the housing, the adhesive pad being configured to removably secure the housing to a patient's skin; a needle movable between a first position and a second position, in which the needle is fully received within the interior of the housing, and in the second position, at least a portion of the needle extending through the first port; a button disposed on the outer surface of the housing, the button being configured to move the needle from the first position to the second position; a cannula disposed around the outside of the needle; a pump received within the interior of the housing, the pump being in fluid communication with the cannula; and a reservoir disposed outside the interior of the housing and offset from the periphery of the housing, the reservoir being in fluid communication with the second port and the pump. Attached Figure Description

[0005] Figure 1 This is a perspective view of a drug delivery device according to a non-limiting embodiment described herein; Figure 2 This is a rear perspective view of a drug delivery device according to a non-limiting embodiment described herein; Figure 3 This is a perspective view of a drug delivery device according to a non-limiting embodiment described herein; Figure 4 This is a schematic diagram of a drug delivery device according to a non-limiting embodiment described herein; Figure 5 This is a schematic diagram of a drug delivery device according to a non-limiting embodiment described herein; Figure 6 This is a top view of a drug delivery device according to a non-limiting embodiment described herein; Figure 7 This is a partial exploded perspective view of a drug delivery device according to a non-limiting embodiment described herein; Figure 8 This is a perspective view of a drug delivery device according to a non-limiting embodiment described herein; Figure 9 This is a top view of a drug delivery device according to a non-limiting embodiment described herein; Figure 10 This is a top view of a drug delivery device according to a non-limiting embodiment described herein; Figure 11 This is a top view of a drug delivery device according to a non-limiting embodiment described herein; Figure 12 This is a top view of a drug delivery device according to a non-limiting embodiment described herein; Figure 13 This is a top view of a drug delivery device according to a non-limiting embodiment described herein; Figure 14A and Figure 14B This is a top view of a drug delivery device according to a non-limiting embodiment described herein; Figure 15 A front view of an adhesive pad according to a non-limiting embodiment described herein; Figure 16 A front view of an adhesive pad according to a non-limiting embodiment described herein; Figure 17 A front view of an adhesive pad according to a non-limiting embodiment described herein; Figure 18 A front view of an adhesive pad according to a non-limiting embodiment described herein; Figure 19 A front view of an adhesive pad according to a non-limiting embodiment described herein; Figure 20 A schematic diagram of a drug delivery device according to a non-limiting embodiment described herein; and Figure 21 These are illustrations of non-limiting embodiments or aspects of the various components of the drug delivery device described herein. Detailed Implementation

[0006] The following description is provided to enable those skilled in the art to make and use the described embodiments intended for carrying out the invention. However, various modifications, equivalents, variations, and substitutions will be apparent to those skilled in the art. Any and all of these modifications, variations, equivalents, and substitutions are intended to fall within the spirit and scope of the invention.

[0007] In the following text, for descriptive purposes, the terms “upper,” “lower,” “right,” “left,” “vertical,” “horizontal,” “top,” “bottom,” “lateral,” “longitudinal,” and their derivatives shall be used in connection with the present invention as oriented as shown in the accompanying drawings. However, it should be understood that the invention may employ various alternative variations unless explicitly stated otherwise. It should also be understood that the specific devices shown in the accompanying drawings and described in the following specification are merely exemplary embodiments of the invention. Therefore, specific dimensions and other physical features associated with the embodiments disclosed herein should not be considered limiting.

[0008] It should be understood that any range of values ​​listed in this article is intended to include all values ​​and subranges contained therein. For example, the range “1 to 10” is intended to include all subranges (inclusive) between the stated minimum value of 1 and the stated maximum value of 10, that is, a minimum value equal to or greater than 1 and a maximum value equal to or less than 10.

[0009] This document provides a wearable drug delivery device having a large reservoir to allow delivery of a wider variety of therapeutic compositions and including features that increase patient compliance and the device's adhesion to the patient, thereby ensuring complete delivery of the therapeutic composition. Various components that can be used in the drug delivery device described herein, and the functions of these components, are described in U.S. Patent Application Publications Nos. 2022 / 0211952, 2022 / 0211935, 2022 / 0211939, 2022 / 0211936, and 2022 / 0211940, the contents of which are incorporated herein by reference in their entirety.

[0010] Go to Figure 1 and Figure 2 This illustration shows a non-limiting embodiment of a wearable drug delivery device 100. The drug delivery device 100 includes a housing 110 defining a periphery. The housing 110 may have a top surface, a bottom surface, a front surface, a rear surface, and side surfaces. The housing 110 may be formed of any suitable material, and as will be discussed below, the housing may include multiple segments, which in a non-limiting embodiment may be separable from each other. The drug delivery device 100 also includes a container 120 connectable to the housing 110, but the container extends outside the periphery of the housing 110. The container 120 may extend from any surface of the housing 110. Figure 1 As shown, container 120 extends from one side of housing 110. Similarly... Figure 1 As shown, the drug delivery device 100 may include an adhesive pad 130, which can be configured to secure the drug delivery device 100 to a patient. Suitable adhesives, including those with antimicrobial and / or biocompatibility characteristics, are known to those skilled in the art and can be used with the drug delivery device 100. In a non-limiting embodiment (discussed below), the adhesive pad 130 may include an adhesive layer and a backing layer. Figure 1 As shown, the drug delivery device 100 may also include a button 150, which may be a mechanical or electronic button, configured to cause a needle (not shown) to puncture the patient's skin to allow a cannula (not shown) to be placed through the patient's skin, for example, subcutaneously, for delivery of the therapeutic composition. Button 150 and insertion mechanism 246 (e.g., in...) Figure 4 (As shown herein) can be mechanically and / or electrically connected, such that the injection mechanism can be a mechanical / manual injection mechanism responsive to pressing button 150, and / or can be an electrical / automatic injection mechanism, for example, based on instructions received from a processor in response to pressing button 150. In a non-limiting embodiment, the drug delivery device 100 can be remotely activated by one or more computer components described herein. Figure 1 As shown, the drug delivery device 100 may also include a display 140. The display 140 may be configured to display any useful information. In a non-limiting embodiment, the display 140 is configured to display the delivery status of the therapeutic composition.

[0011] Go to Figure 2 The image shows a rear view of a non-limiting embodiment of a drug delivery device 100. The drug delivery device 100 may include one or more ports 160 to allow drug delivery and / or filling of the container 120. Ports through which needles and cannulas pass may connect with openings in the adhesive pad 130 (e.g., Figure 2 The port 160 shown is aligned or can pass through the adhesive pad 130. A non-limiting embodiment is shown that includes a port 160 for filling the container 120, for example, by using a syringe (e.g., a pre-filled syringe).

[0012] Go to Figures 3 to 5 A non-limiting embodiment of a drug delivery device 100 is shown, wherein the housing 110 is divided into a plurality of discrete segments, and these segments may optionally be separated from each other. Although in Figure 4 Not shown, but those skilled in the art will understand that the various components within the housing 112 can be interconnected electrically, mechanically, and / or fluidly (as will be referenced later, for example). Figure 20 (As shown). For example, the drug delivery device 100 may be divided into a power pack module 210 and a fluid module 220, the fluid module 220 including a container portion 230 and an injection portion 240. The power pack module 210 may include electronic components, such as a power supply 212, a motor 214, and one or more computer components 180 (e.g., a processor and / or storage device). In a non-limiting embodiment, the power pack module 210 includes a pump 242 and / or a motor 214. In a non-limiting embodiment, the fluid module 220 includes a pump 242. As used herein, the term "computer component" includes... Figure 21 The figure shows one or more components, as well as those described herein with reference to the figure. In a non-limiting embodiment, the power unit module 210 may be reusable (e.g., the power unit module 210 may be separate from the container portion 230 and the injection portion 240). In a non-limiting embodiment, the flow control module 220 is disposable. In a non-limiting embodiment, the power source 212 is a rechargeable power source or may be replaced.

[0013] In a non-limiting embodiment, the power unit module 210 and / or the flow control module 220 may include one or more sensors for detecting one or more parameters of the drug delivery device 100 and / or the environment. Exemplary sensors may include those for detecting the container 120, the flexible reservoir 232, or one or more fluid conduits included in the drug delivery device 100 (e.g., Figure 20 Sensors for volume, flow rate, pressure, and / or occlusion within the fluid conduit (as illustrated in the example) and / or sleeve 107. These sensors can communicate with and provide data to the processor, which can then use this data to control the motor 214 and / or pump 242. Figure 5 An embodiment is shown in which the sensor 133 is located at a certain position inside the housing 112, but those skilled in the art will understand that different types of sensors will have to be arranged at certain positions inside the housing 112.

[0014] Continue to refer to Figures 3 to 5 The flow control module 220 may include a container portion 230, which may include a container 120 and, optionally, a flexible reservoir 232 received within the container 120. In non-limiting embodiments, the container 120 and / or the flexible reservoir 232 may be formed of a substantially or completely transparent material to facilitate visualization of any therapeutic composition contained therein or added thereto. Those skilled in the art will understand that any therapeutic composition can be delivered using the device described herein; however, those therapeutic compositions delivered over a time delay and / or over a longer time span may be particularly suitable for use with the drug delivery device described herein.

[0015] The flow control module 220 may further include an injection portion 240, which may include a pump 242, a filling port 244, and an insertion mechanism 246. In a non-limiting embodiment, such as when there is only one port 160 in the housing 110, the filling port 244 and the insertion mechanism 246 may have the same structure. The pump 242 may be electrically and / or mechanically connected to the motor 214 and fluidly connected to the container 120 and the insertion mechanism 246. The filling port 244 may be associated with one or more ports 160 disposed on the surface of the housing 110 and may be in fluid communication with the container 120. The insertion mechanism 246 may be in fluid communication with the pump 242 and referenced to... Figure 5 It may include a needle 157 for piercing the user's skin and a cannula 107 for delivering a therapeutic composition from a container 120 to the patient. The needles and cannulas used in wearable drug delivery devices are known to those skilled in the art and can be formed from any suitable material.

[0016] Go to Figure 6 and Figure 7A non-limiting embodiment of a drug delivery device 100 is shown, highlighting a removable pivot connection between the container 120 and the housing 110. Not wishing to be bound by theory, it is believed that the pivot connection between the housing 110 and the container 120 allows the drug delivery device 100 to conform to the patient's waist / stomach, as wearable drug delivery devices are typically placed at the patient's waist / stomach. As mentioned above, the container 120 may be removable from the housing 110 to allow for the reuse of one or more components, such as the container 120, the power unit module 210, and / or the injection portion 240. Although Figure 6 as well as Figures 9 to 11 The diagram shows the container 120 pivoting over a 40-degree span, but those skilled in the art will understand that any amount of pivoting is possible over any angular variation to allow the drug delivery device 100 to adhere securely to the patient.

[0017] Go to Figure 8 The image shows a non-limiting embodiment of a drug delivery device 100, wherein a container 120 extends from the bottom surface of a housing 110. Figure 8 The drug delivery device 100 in the illustrated embodiment may include any of the features described herein, including different, separable modules / parts, button 150, port 160, display 140 and / or adhesive pad 130.

[0018] Go to Figures 9 to 14B This illustration shows non-limiting embodiments of various arrangements of the housing 110, container 120, and adhesive 130 of a drug delivery device 100. As briefly described above, the adhesive pad 130 may include an adhesive layer 132 and a backing layer 134, the backing layer 134 covering the adhesive layer 132 prior to application to a patient's body. The adhesive layer 132 may be formed of any suitable material and may include any suitable one or more adhesives, optionally including adhesives having biocompatibility, skin breathability, and / or antimicrobial properties or additives (e.g., chlorhexidine gluconate (CHG)). In various non-limiting embodiments, the adhesive layer 132 may be a continuous layer extending substantially along the entire length of the housing 110 and container 120, and in non-limiting embodiments, extending beyond the periphery of the housing 110 and / or container 120. In non-limiting embodiments, for example, as... Figure 10 and Figure 11As shown, adhesive layer 132 may be discontinuous; for example, adhesive layer 132 may be provided only on the rear surface (132a) of housing 110 and / or the rear surface (132b) of container 120, and, for example, not adjacent to the pivot point between housing 110 and container 120. In any embodiment, backing layer 134 may be discontinuous (having portions 134a and 134b that substantially correspond to adhesive layers 132a and 132b) (e.g. Figure 10 As shown), or continuous (as shown). Figure 11 (As shown).

[0019] Go to Figure 13 In a non-limiting embodiment, the housing 110 of the injection portion 240 of the power unit module 210 and the flow control module 220, as discussed above, can be configured to be approximately as follows: Figure 1 As shown. The container portion 230 of the flow control module 220, which may include a flexible reservoir 232, may have a curved rear surface, for example, to conform to the patient's waist or stomach, thereby allowing for a more robust attachment of the adhesive layer 132. Also as described above, a pivot point 170 may be included between the housing 110 (including the power assembly module 210 and the injection portion 240) and the container module 230.

[0020] about Figures 14A to 14B A non-limiting arrangement of the drug delivery device 100 is shown. Figure 14A The housing 110 of the injection portion 240 of the flow control module 220, which may include the power unit module as discussed above, can be configured to approximately as follows: Figure 1 As shown. The container portion 230 of the flow control module 220, which may include a flexible reservoir 232, may have a curved rear surface, for example, to conform to the patient's waist or stomach, thereby allowing for a more robust attachment of the adhesive layer 132. Figure 14A In this design, container module 230 is divided into multiple segments, each with a pivot point 170 between them. Container module 230 may or may not independently include the flexible reservoir 232, may have a curved rear surface, and may be in fluid communication with a port on housing 110 and a pump received within injection portion 240. The container module can be fluidly connected via piping. Figure 14BIn this embodiment, the injection portion 240 of the power unit module 210 and the flow control module 220 are separated by a pivot point 170, and the container portion 230 of the injection portion 240 and the flow control module 220, which may include a flexible reservoir 232, may have a curved rear surface, for example, to conform to the patient's waist or stomach, thereby allowing for a more robust attachment of the adhesive layer 132. In various embodiments, the mechanical connection between the power unit module 210 and the injection portion 240 of the flow control module 220 can be achieved via a universal joint or friction coupling, the electrical connection can be achieved via a ribbon cable, and the fluid connection can be achieved via conduits between the internal components of the modules.

[0021] Go to Figures 15 to 19 The illustration shows a non-limiting embodiment of adhesive layer 132, which can be used in any embodiment of the drug delivery device 100 described herein to make the adhesive flexible and provide comfort when wearing the device. Figures 15 to 19 Non-limiting embodiments may include, for example Figures 9 to 14B In the arrangement of the shown housing 110 and container 120, the adhesive layer 132 may include a transition portion 136, which may be arranged, for example, to contact the patient's skin near a pivot point between the housing 110 and container 120, between the power assembly module 210 and injection portion 240, between the injection portion 240 and container module 230, and / or between the respective container modules 230. The transition portion 136 may include a narrowing, and the narrowing may include one or more openings passing through it, which can be used to increase the flexibility of the transition portion 136. The opening may be circular (e.g., ...). Figure 15 and Figure 16 (as shown), and / or can be elongated (such as...) Figure 17 and Figure 18 (As shown). In a non-limiting embodiment, the transition portion 136 may include multiple corrugated portions, such as... Figure 19 As shown in the non-limiting embodiments.

[0022] Go to Figure 20 The diagram shows a non-limiting embodiment of the drug delivery device 100. Figure 20 The connections between various modules and components of the drug delivery device 100 are shown. Although in Figure 20The illustrations depict fluid connections, but those skilled in the art will understand that any one or more components can be mechanically and / or electrically connected, and that the connection can be a physical and / or wireless connection for data transmission between the components. As described above, the drug delivery device 100 can be divided into a power unit module 210, which includes a power source 212 (e.g., one or more batteries (rechargeable or other batteries)), a motor 214, and one or more computer components 180 (e.g., a processor and / or storage device). Figure 21 Further description is provided of one or more computer components that may be included in a non-limiting embodiment of the drug delivery device 100. The drug delivery device 100 may include a flow control module 220, which may include an injection portion 240 including an insertion mechanism 246 comprising a needle and / or cannula (not shown). The flow control module 220 may also include a container module comprising a container 120. As described, the container 120 may be in fluid communication with a port 160 in the housing 110, for example, via fluid conduits 122, 129. The container 120 and / or flexible reservoir 232 may also be in fluid communication with a pump 242, optionally via fluid conduits 122, 129, and 124. The pump 242 may be in fluid communication with the insertion mechanism 246, for example, via fluid conduit 126. Optionally, the fluid conduit 126 may include a reservoir adjacent to the insertion mechanism 246.

[0023] Now for reference Figure 21 The illustration shows an example component of an exemplary computing device 900 that can be used in the drug delivery device 100 described herein. This computing device 900 may correspond to a connection module of a drug delivery device as described herein, a user device as described herein, and / or a component within a healthcare system as described herein. Figure 21 As shown, the computing device 900 may include a bus 902, a processor 904, a memory 906, a storage unit 908, an input unit 910, an output unit 912 and / or a communication interface 914.

[0024] Bus 902 may include components that allow communication between the various components of computing device 900. In some non-limiting embodiments, processor 904 may be implemented in hardware, software, or a combination of hardware and software. For example, processor 904 may include processors (e.g., central processing unit (CPU), graphics processing unit (GPU), and / or accelerated processing unit (APU), etc.), microprocessors, digital signal processors (DSPs), and / or any processing component that can be programmed to perform functions (e.g., field-programmable gate array (FPGA) and / or application-specific integrated circuit (ASIC), etc.). Memory 906 may include random access memory (RAM), read-only memory (ROM), and / or another type of dynamic or static memory (e.g., flash memory, magnetic memory, and / or optical memory, etc.) that stores information and / or instructions for use by processor 904.

[0025] Storage component 908 may store information and / or software related to the operation and use of computing device 900. For example, storage component 908 may include hard disk (e.g., magnetic disk, optical disk, magneto-optical disk, and / or solid-state drive, etc.), compact disc (CD), digital versatile disc (DVD), floppy disk, cassette tape, magnetic tape, and / or another type of computer-readable medium with a corresponding drive.

[0026] Input component 910 may include components that allow computing device 900 to receive information, for example, via user input (e.g., a touchscreen display, keyboard, keypad, mouse, buttons, switches, and / or microphones, etc.). Additionally or alternatively, input component 910 may include sensors for sensing information (e.g., a global positioning system (GPS) component, accelerometer, gyroscope, actuator, microphone, environmental sensors (e.g., temperature sensor, humidity sensor, etc.)). Output component 912 may include components that provide output information from computing device (e.g., a display, speaker, one or more light-emitting diodes (LEDs), haptic indicators, etc.).

[0027] Communication interface 914 may include transceiver-like components (e.g., transceiver, separate receiver and transmitter, etc.) that enable the device (e.g., via a wired connection, a wireless connection, or a combination of wired and wireless connections) to communicate with other devices. Communication interface 914 may allow computing device 900 to send information to and / or receive information from another device. For example, communication interface 914 may include an Ethernet interface, an optical interface, a coaxial interface, an infrared interface, a radio frequency (RF) interface, a universal serial bus (USB) interface, a Wi-Fi® interface, a cellular network interface, a Bluetooth interface, a near-field communication (NFC) interface, etc. Appropriate communication protocols and methods for implementing communication between communication interface 914 and the communication interface of another device (e.g., a computing device (e.g., a desktop computer, a laptop computer, a smartphone, a smartwatch, a PDA, a tablet computer, etc.)) may include, for example, encryption using a secure socket layer (SSL) (e.g., using a public / private key pair known in the art). Additional security protocols are disclosed, for example, in U.S. Patent Nos. 9,445,264 and 9,463,325, the contents of which are incorporated herein by reference in their entirety. In the non-limiting embodiments described herein, the communication interface 914 is disposed on the plunger rod. In the non-limiting embodiments, the communication interface 914 is configured to transmit data, but not to receive data transmitted by a computing device (e.g., a user's smartphone).

[0028] A computing device can perform one or more of the processes described herein. The computing device can execute these processes based on software instructions stored in a computer-readable medium (e.g., memory 906 and / or storage unit 908) executed by processor 904 and / or instructed by a separate computing device. A computer-readable medium (e.g., a non-transitory computer-readable medium) is defined herein as a non-transitory memory device. A non-transitory memory device includes memory space located within a single physical memory device or memory space distributed across multiple physical memory devices.

[0029] Software instructions may be read into memory 906 and / or storage unit 908 via communication interface 914 from another computer-readable medium or from another device. When executed, the software instructions stored in memory 906 and / or storage unit 908 may cause processor 904 to perform one or more processes described herein. Additionally or alternatively, hardwired circuitry may be used in place of or in combination with software instructions to perform one or more processes described herein. Therefore, the embodiments described herein are not limited to any particular combination of hardware circuitry and software.

[0030] Referring to the accompanying drawings, the drug delivery device 100 can be operated as follows: A doctor or patient can fill the container 120 and / or the flexible reservoir 232, for example, with a syringe. The drug delivery device 100 can then be applied to the patient, for example, using an adhesive pad 130. The doctor or patient can then press the button 150 to initiate the drug delivery process. In a non-limiting embodiment, the drug delivery process can be initiated by piercing the patient's skin with the needle 157. By piercing the patient's skin, a cannula 107, around which the needle 157 is received, can be similarly passed through the patient's skin and positioned, for example, at a location where the therapeutic composition can be delivered subcutaneously. The button 150 can be mechanically connected to the insertion mechanism 246 such that pressing the button 150 causes a corresponding translation of the insertion mechanism 246 and the needle 157. In one embodiment, button 150 communicates with computer component 180 (e.g., a processor), and action on button 150 causes the processor to instruct insertion mechanism 246 (e.g., based on programming instructions stored in memory 906 included in computer component 180) to move needle 157 to puncture the patient's skin and place cannula 107. In a non-limiting embodiment, drug delivery can be initiated by actuation of button 150 or another button included on housing 110 (or via a wireless interface, e.g., via a mobile application). In a non-limiting embodiment, drug delivery can be delayed based on mechanical and / or electromechanical delay components, and / or based on programming instructions executed by the processor. After this delay (which can be predetermined based on the treatment composition to be delivered), motor 214 (optionally under the control of the processor) can cause pump 242 to begin drawing treatment composition from container 120 and / or flexible reservoir 232 and dispensing treatment composition through cannula 107. In one embodiment, the processor can cause display 140 to provide indication of the drug delivery status. In an embodiment, the processor may control one or more indicators to provide visual, auditory, and / or tactile indications of the completion of the drug delivery process. After drug delivery has been completed, the insertion mechanism 246 (optionally under the control of the processor), the retracted cannula 107, and the drug delivery device 100 may be disposed of, or in an embodiment, one or more modules and / or portions of the drug delivery device 100 may be disposed of or reused.

[0031] Although this disclosure has been described in detail based on embodiments currently considered to be the most practical and preferred for illustrative purposes, it should be understood that such detail is for that purpose only, and that this disclosure is not limited to the disclosed embodiments. Rather, this disclosure is intended to cover modifications and equivalent arrangements falling within the spirit and scope of the appended claims. For example, it should be understood that this disclosure contemplates that, to the extent possible, one or more features of any embodiment may be combined with one or more features of any other embodiment.

Claims

1. A wearable drug delivery device, the wearable drug delivery device comprising: A housing having a periphery and defining an interior, the housing having a first port and a second port disposed on its outer surface; An adhesive pad is disposed on the outer surface of the housing and is configured to removably attach the housing to the patient's skin; A needle that is movable between a first position and a second position, wherein in the first position the needle is fully received inside the housing, and in the second position at least a portion of the needle extends through the first port; A button is disposed on the outer surface of the housing and is configured to move the needle from the first position to the second position. A cannula, the cannula being arranged around the outside of the needle; A pump, which is housed within the housing and is in fluid communication with the casing; as well as A reservoir is disposed outside the interior of the housing and offset from the periphery of the housing, and the reservoir is in fluid communication with the second port and the pump.

2. The wearable drug delivery device according to claim 1, wherein, The housing includes a top surface, a bottom surface, a front surface, a rear surface, and two side surfaces, wherein the adhesive pad is disposed on the rear surface of the housing.

3. The wearable drug delivery device according to claim 2, wherein, The reservoir extends from the bottom surface of the housing, and optionally at a pivot point.

4. The wearable drug delivery device according to claim 2, wherein, The reservoir extends from the side surface of the housing, and optionally at a pivot point.

5. The wearable drug delivery device according to claim 4, wherein, The reservoir includes a front surface and a rear surface, wherein the rear surface is curved.

6. The wearable drug delivery device according to claim 4 or 5, wherein, The reservoir comprises multiple sections, with pivots between adjacent sections.

7. The wearable drug delivery device according to claim 5 or 6, wherein, The adhesive pad is disposed on the rear surface of the reservoir.

8. The wearable drug delivery device according to claim 2, wherein, The second port is located on the front surface of the housing.

9. The wearable drug delivery device according to claim 2, wherein, The second port is disposed on the rear surface of the housing.

10. The wearable drug delivery device according to claim 2, wherein, The button is located on the front surface of the housing.

11. The wearable drug delivery device according to claim 2, wherein, The housing comprises multiple segments that are separable from each other.

12. The wearable drug delivery device according to claim 11, wherein, The first section of the housing includes a power source and a motor configured to actuate the pump.

13. The wearable drug delivery device according to claim 12, wherein, The first segment also includes a processor.

14. The wearable drug delivery device according to claim 12 or 13, wherein, The second section of the housing includes the pump, the needle, the first port, and the second port.

15. The wearable drug delivery device according to any one of claims 12 to 14, wherein, The rear surface of at least one of the plurality of housing segments is curved.

16. The wearable drug delivery device according to any one of claims 2 to 15, wherein the wearable drug delivery device further comprises a display located on the outer surface of the housing.

17. The wearable drug delivery device according to claim 16, wherein, The display is arranged on the front and / or top surface of the housing.

18. The wearable drug delivery device according to claim 17, wherein, The display is configured to provide a visual indication of the progress of drug delivery.

19. The wearable drug delivery device according to any one of claims 1 to 15, wherein, The storage device includes a flexible container housed within a rigid container.

20. The wearable drug delivery device according to claim 19, wherein, The flexible container is in fluid communication with the pump and the second port.

21. The wearable drug delivery device according to claim 19 or 20, wherein, Both the rigid container and the flexible container are substantially transparent.

22. The wearable drug delivery device according to any one of claims 1 to 21, wherein, The adhesive pad is disposed on the housing and the reservoir.

23. The wearable drug delivery device according to claim 22, wherein, The adhesive pad includes a first segment and a second segment connected by a transition segment.

24. The wearable drug delivery device according to claim 23, wherein, The transition section includes multiple openings in the pad.

25. The wearable drug delivery device according to claim 24, wherein, The plurality of openings are circular or elongated.

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