Sample loading device of analysis system, sample analysis system, full-laboratory automatic assembly line and control method of full-laboratory automatic assembly line

Abstract

The invention discloses an analysis system sample loading device, which is provided with a sample loading and unloading module, a sample transfer module, a first sample scheduling transmission module and a second sample scheduling transmission module. Therefore, the scheduling of the samples in the sample loading device of the analysis system and the loading and unloading operation of the samples are realized; the first sample scheduling transmission module can be connected with an analysis system transmission device, and realizes sample transmission with the analysis system transmission device, so that a sample can be conveniently transmitted into a sample analyzer for detection; and sample transmission is realized between the second sample scheduling transmission module and the main rail transmission system. The invention further discloses a sample analysis system, a TLA and a control method of the TLA. When the sample analysis system is applied to the TLA, the main track transmission system can be conveniently compatible with sample analysis systems of different specifications through the second sample scheduling transmission module, namely, the compatibility can be improved.

Description

Technical Field

[0001] This invention belongs to the field of in vitro diagnostic technology, specifically an analytical system sample loading device, a sample analysis system, a fully automated laboratory production line, and its control method. Background Technology

[0002] With the rapid development of medical technology, the demand for sample testing is increasing. To meet this demand, Total Laboratory Automation (TLA) systems have emerged to test samples. In related technologies, TLA typically includes a sample preparation system, several sample analysis systems, and a main track transport system for transferring and exchanging samples between these systems. The sample analysis system usually supports cascading several (typically 1-4) sample analyzers and their transport devices. The sample preparation system is mainly used to receive the samples to be tested and to transport them to the main track transport system. The main track transport system is directly connected to the transport devices of the sample analysis systems, used to transport the samples to be tested to the corresponding sample analyzers for testing.

[0003] In related technologies, when configuring TLA, the main rail transport system and the sample analysis system may be manufactured by the same company and have good compatibility, or they may be manufactured by different companies, resulting in poor compatibility. Of course, even if they are manufactured by the same company, sample analysis systems applied to different application areas may have different compatibility with the pipeline main rail transport system. Related technologies all use a direct connection between the main rail transport system and the analysis system transport device. This places high requirements on the consistency or compatibility between the main rail transport system and the analysis system transport device, which is not conducive to the integration of the analysis system transport device into the TLA, hindering the open use and promotion of TLA.

[0004] Furthermore, in related technologies, the TLA (Tracking and Analysis) system loads samples for testing into a pre-processing system and then transfers them to the sample analysis system via a main rail transport system. If either the pre-processing system or the main rail transport system fails, the entire TLA system will be paralyzed, resulting in poor disaster recovery capabilities and difficulty in guaranteeing sample turnaround time (TAT). A failure in either the pre-processing system or the main rail transport system means that testing can only continue after the fault is cleared, making it difficult to meet the needs of various testing application scenarios. Summary of the Invention

[0005] The main objective of this invention is to provide an analytical system sample loading device, a sample analysis system, a fully automated laboratory production line, and a control method thereof, thereby solving the problem of poor compatibility when the sample analysis system is integrated into a fully automated laboratory production line.

[0006] To achieve the above objectives, the present invention provides the following technical solution:

[0007] This invention first proposes an analytical system sample loading device, including a sample loading device body, which is provided with a sample loading and unloading module, a sample transfer module, a first sample scheduling and transmission module and a second sample scheduling and transmission module.

[0008] The sample loading / unloading module is configured to load or unload samples;

[0009] The sample transfer module is configured to at least implement sample transfer between the sample loading / unloading module and the first sample scheduling and transmission module, and between the sample loading / unloading module and the second sample scheduling and transmission module; or, the sample transfer module is configured to at least implement sample transfer between the sample loading / unloading module and the first sample scheduling and transmission module, between the sample loading / unloading module and the second sample scheduling and transmission module, and between the first sample scheduling and transmission module and the second sample scheduling and transmission module.

[0010] The first sample scheduling and transmission module is configured to interface with the analysis system transmission device to realize sample interaction between the two devices; the first sample scheduling and transmission module is provided with a first sample transfer position for the sample transfer module to transfer samples; the analysis system transmission device is part of the sample analysis system and is used at least to transmit samples to the corresponding sample analyzer in the sample analysis system.

[0011] The second sample scheduling and transmission module is configured to interface with the main rail transmission system to realize sample interaction with the main rail transmission system; the second sample scheduling and transmission module is equipped with a second sample transfer position for the sample transfer module to transfer samples; the main rail transmission system is part of the fully automated laboratory pipeline and is configured to realize sample interaction between the various systems included in the fully automated laboratory pipeline.

[0012] Optionally, the sample loading and unloading module uses a sample loading vehicle to load samples, and the first sample scheduling and transmission module and the second sample scheduling and transmission module use the first sample transmission vehicle and the second sample transmission vehicle to transmit samples, respectively; at least one of the first sample transmission vehicle and the second sample transmission vehicle is a single-tube transmission vehicle that can only store one sample tube, or a multi-tube transmission vehicle that can simultaneously accommodate at least two sample tubes.

[0013] Optionally, the sample loading device body is equipped with a centrifugation module, which includes a centrifuge and a centrifugation adapter; the sample transfer module is also configured to transfer the sample to the centrifugation adapter and transfer the centrifugation adapter from the centrifuge to the sample loading and unloading module.

[0014] Optionally, at least two of the sample loading vehicle, the first sample transport vehicle, and the second sample transport vehicle are the same physical vehicle or different physical vehicles; and / or, the first sample transport vehicle and the third sample transport vehicle used by the analysis system transport device are the same physical vehicle or different physical vehicles; and / or, the second sample transport vehicle and the fourth sample transport vehicle used by the main rail transport system are the same physical vehicle or different physical vehicles.

[0015] Optionally, at least two of the sample loading vehicle, the first sample transport vehicle, and the centrifuge adapter are the same physical vehicle or different physical vehicles; or, the first sample transport vehicle and the centrifuge adapter are the same physical vehicle, and the sample transfer module is further configured to transfer the centrifuge adapter from inside the centrifuge or from the sample loading / unloading module to the first sample scheduling and transport module.

[0016] Optionally, the first sample scheduling and transmission module is provided with a first interface and a second interface; the first interface is used to receive the first sample transmission carrier input from the analysis system transmission device; the second interface is used to output the first sample transmission carrier to the analysis system transmission device; and / or, the second sample scheduling and transmission module is provided with a third interface and a fourth interface, the third interface is used to receive the second sample transmission carrier input from the main rail transmission system, and the fourth interface is used to output the second sample transmission carrier to the main rail transmission system.

[0017] Optionally, when the first sample transmission carrier is a single-tube transmission carrier, the first interface and the second interface are independent of each other; the first sample scheduling transmission module includes a first sample scheduling track and a second sample scheduling track with opposite transmission directions; the first sample scheduling track is connected to the first interface; the second sample scheduling track is connected to the second interface; when the first sample transmission carrier is a multi-tube transmission carrier, the first interface and the second interface overlap; the first sample scheduling transmission module adopts a bidirectional transmission track with two opposite transmission directions; and / or, the second sample scheduling transmission module includes a third sample scheduling track and a fourth sample scheduling track with opposite transmission directions; the third sample scheduling track is connected to the third interface, and the fourth sample scheduling track is connected to the fourth interface.

[0018] The present invention also proposes a fully automated laboratory production line, including a pretreatment system, a main rail transport system, and at least one sample analysis system arranged along the main rail transport system, wherein at least one of the sample analysis systems is the sample analysis system described above.

[0019] The preprocessing system interfaces with the main rail transmission system to enable sample interaction;

[0020] The sample loading device of the analysis system is configured to be located between the main rail transmission system and the analysis system transmission device. The first sample scheduling transmission module is connected to the analysis system transmission device, and the second sample scheduling transmission module is connected to the main rail transmission system.

[0021] This invention also proposes a control method for the above-mentioned fully automated laboratory production line, comprising at least one of the following control steps:

[0022] The control sample transfer module transfers the sample from the sample loading and unloading module to the first sample scheduling and transmission module, and controls the first sample scheduling and transmission module to deliver the sample to the analysis system transmission device, so that the analysis system transmission device can transmit the sample to the corresponding sample analyzer.

[0023] The control sample transfer module transfers samples from the sample loading and unloading module to the second sample scheduling and transmission module, so that the second sample scheduling and transmission module can deliver the samples to the main rail transmission system, and control the main rail transmission system to transmit the samples to at least one of the pre-processing system, the recovery position, and other sample analysis systems;

[0024] The control and analysis system transmission device delivers the sample to the first sample scheduling and transmission module, and controls the sample transfer module to transfer the sample from the first sample scheduling and transmission module to the sample loading and unloading module, and then from the sample loading and unloading module to the second sample scheduling and transmission module, so that the second sample scheduling and transmission module can deliver the sample to the main rail transmission system; or controls the sample transfer module to directly transfer the sample from the first sample scheduling and transmission module to the second sample scheduling and transmission module, so that the second sample scheduling and transmission module can deliver the sample to the main rail transmission system.

[0025] The control main rail transmission system delivers samples to the second sample scheduling and transmission module, and controls the sample transfer module to transfer samples from the second sample scheduling and transmission module to the sample loading and unloading module, and then from the sample loading and unloading module to the first sample scheduling and transmission module, so that the first sample scheduling and transmission module can deliver the samples to the analysis system transmission device. Alternatively, the control sample transfer module can directly transfer samples from the second sample scheduling and transmission module to the first sample scheduling and transmission module, so that the first sample scheduling and transmission module can deliver the samples to the analysis system transmission device.

[0026] The beneficial effects of this invention are as follows:

[0027] The sample loading device for the analytical system provided by this invention includes a sample loading / unloading module, a sample transfer module, a first sample scheduling and transmission module, and a second sample scheduling and transmission module. The sample transfer module enables sample transfer between the first sample scheduling and transmission module and the sample loading / unloading module, as well as between the second sample scheduling and transmission module and the sample loading / unloading module, thereby achieving sample scheduling and loading / unloading operations within the analytical system loading device. The first sample scheduling and transmission module can interface with the analytical system transmission device of the sample analysis system, enabling sample interaction to transfer samples to the sample analyzer for testing. The second sample scheduling and transmission module interfaces with the TLA main rail transmission system to achieve sample interaction; that is, the sample analysis system can act as a transfer... The first and second sample scheduling and transmission modules of the adapter interface with the TLA main rail transmission system, which can improve the compatibility between the sample analysis system and TLA. Moreover, the first and second sample scheduling and transmission modules are decoupled, and the sample interaction between the two is realized through the sample transfer module. This makes it easy to adapt the first sample scheduling and transmission module to the analysis system transmission device of the sample analysis system, and to adapt the second sample scheduling and transmission module to the TLA main rail transmission system. There is no need to worry about the compatibility between the first and second sample scheduling and transmission modules during the adaptation process. Furthermore, the first and second sample scheduling and transmission modules do not have strong connection requirements, which can further improve the flexibility and compatibility of the sample analysis system interface with TLA.

[0028] The sample loading / unloading module and sample transfer module of the analytical system sample loading device provided by this invention enable the analytical system sample loading device to have independent sample loading and scheduling functions; after the sample analysis system including the analytical system sample loading device is connected to TLA through the analytical system sample loading device, it can realize, but is not limited to, the following functions:

[0029] The samples loaded onto the sample analysis system have at least one of the following transport pathways:

[0030] The data is transmitted through its analysis system transmission device to its corresponding sample analyzer for analysis and processing.

[0031] The samples are transmitted to other TLA sample analysis systems via the main rail transmission system.

[0032] Transmitted to the TLA's pre-processing and / or post-processing systems via the main rail transmission system;

[0033] The second sample scheduling and transmission module of the sample loading device of the sample analysis system can also receive samples from the main rail transmission system. The samples received may have at least one of the following processing methods, but are not limited to:

[0034] The received samples are carried in its sample loading and unloading module;

[0035] The samples are transmitted to their corresponding sample analyzers via the first sample scheduling and transmission module and the analysis system transmission device for analysis and processing.

[0036] The samples are transmitted to other TLA sample analysis systems via the second sample scheduling and transmission module and the main rail transmission system; or via the first sample scheduling and transmission module, the analysis system transmission device, the second sample scheduling and transmission module, and the main rail transmission system.

[0037] The samples are transmitted to the TLA preprocessing system and / or postprocessing system via the second sample scheduling and transmission module and the main rail transmission system; or, the samples are transmitted to the TLA preprocessing system and / or postprocessing system via the first sample scheduling and transmission module, the analysis system transmission device, the second sample scheduling and transmission module, and the main rail transmission system.

[0038] It is evident that the TLA provided by this invention has higher fault tolerance and better reliability, including but not limited to:

[0039] Under the condition of TLA's preprocessing system failure, the sample loading device of the sample analysis system can realize the loading and scheduling of samples, that is, the sample loading device of the analysis system can replace the preprocessing system.

[0040] Even under the condition of a failure in the analysis system's own transmission device, its sample loading device can still perform sample loading and scheduling normally, serving as the sample input and output module of TLA.

[0041] Under the condition of a failure in the main rail transmission system, the sample loading device of the sample analysis system can, on the one hand, operate offline (i.e. disconnected from the main rail transmission system) to normally load and schedule samples within the sample analysis system; on the other hand, it can also be combined with the part of the main rail transmission system that is not faulty and is connected to the sample loading device of the sample analysis system to transfer samples through the faulty part of the main rail system to at least one of other sample analysis systems, preprocessing systems, and postprocessing systems.

[0042] Therefore, when the TLA provided by this invention experiences the above-mentioned failures, it has better disaster prevention capabilities and can better meet the needs of TAT and some urgent test samples.

[0043] In addition, in some application scenarios of the present invention, the sample loading device of the sample analysis system can also work in parallel with the TLA preprocessing system to achieve parallel sample loading, thereby improving the sample processing throughput of TLA. Attached Figure Description

[0044] To make the objectives, technical solutions, and beneficial effects of this invention clearer, the following figures are provided for illustration:

[0045] Figure 1 This is a schematic diagram of the TLA structure provided in an embodiment of the present invention;

[0046] Figure 2-1 This is a schematic diagram of the sample analysis system provided in an embodiment of the present invention;

[0047] Figure 2-2 This is a schematic diagram of the first sample transfer bit setting provided in an embodiment of the present invention. Figure 1 ;

[0048] Figure 2-3 This is a schematic diagram of the first sample transfer bit setting provided in an embodiment of the present invention;

[0049] Figure 2-4 This is a schematic diagram of the first sample transfer bit setting provided in an embodiment of the present invention. Figure 3 ;

[0050] Figure 3 This is a schematic diagram of the structure of the first sample scheduling and transmission module and the analysis system transmission device provided in the embodiments of the present invention when they are configured as a bidirectional transmission track;

[0051] Figure 4 A schematic diagram of the structure of the analysis system transmission device provided in this embodiment of the invention when transferring a sample to the gripper position inside the sample analyzer;

[0052] Figure 5 This is a schematic diagram of the structure of the analysis system transmission device provided in the embodiment of the present invention when transferring a sample to the sampling position inside the sample analyzer;

[0053] Figure 6 A schematic diagram showing the structure of the first sample scheduling and transmission module provided in the embodiments of the present invention, which is divided into a first sample scheduling submodule and a second scheduling submodule, and the second sample scheduling and transmission module is divided into a third sample scheduling submodule and a fourth scheduling submodule;

[0054] Figure 7 This is a schematic diagram of the structure of the sample loading device of the analysis system provided in the embodiment of the present invention when it is equipped with two first sample scheduling and transmission modules;

[0055] Figure 8 This is a schematic diagram of the structure of the sample loading device of the analysis system provided in the embodiment of the present invention when it is equipped with three first sample scheduling and transmission modules;

[0056] Figure 9 This is a schematic diagram of the structure of the analysis system transmission device as several independently operating analysis system transmission modules, provided for an embodiment of the present invention.

[0057] Figure 10 This is a schematic diagram of the structure of the main track transmission system when it is set as several independently operating main track transmission units, as provided in an embodiment of the present invention. Detailed Implementation

[0058] The present invention will be further described below with reference to the accompanying drawings and specific embodiments, so that those skilled in the art can better understand and implement the present invention. However, the embodiments described are not intended to limit the present invention.

[0059] like Figure 1 As shown, the TLA of this embodiment includes a pretreatment system 100, a main rail transport system 200, and at least one sample analysis system 300 arranged along the main rail transport system 200. Of all the sample analysis systems 300, at least one includes an analysis system sample loading device 310 and a system analysis device, the system analysis device including a sample analyzer 330 and an analysis system transport device 320 adapted to the sample analyzer 330. Specifically, the pretreatment system 100 interfaces with the main rail transport system 200 to enable sample interaction. The analysis system sample loading device 310 is configured to be located between the main rail transport system 200 and the analysis system transport device 320. The analysis system transport device 320 is part of the sample analysis system 300 and is used at least to transport samples to the corresponding sample analyzer 330 within the sample analysis system 300.

[0060] like Figures 1-3 As shown, in this embodiment, the sample loading device 310 of the analysis system includes a sample loading device body, on which a sample loading / unloading module 311, a sample transfer module (not shown in the figure), a first sample scheduling and transmission module 400, and a second sample scheduling and transmission module 500 are provided. The sample loading / unloading module 311 is used to load or unload samples. The sample transfer module is used at least to realize sample transfer between the sample loading / unloading module 311 and the first sample scheduling and transmission module 400, and between the sample loading / unloading module 311 and the second sample scheduling and transmission module 500. In some examples, the sample transfer module can also be used to realize direct transfer of samples between the first sample scheduling and transmission module 400 and the second sample scheduling and transmission module 500.

[0061] The first sample scheduling and transmission module 400 interfaces with the analysis system transmission device 320 to enable sample interaction between them. To cooperate with the sample transfer module, the first sample scheduling and transmission module 400 is provided with a first sample transfer position for the sample transfer module to transfer samples. For example, there can be one first sample transfer position, which the sample transfer module can use to grab or place samples on the first sample scheduling and transmission module 400. Alternatively, in some examples, there can be two first sample transfer positions, one for grabbing samples and the other for placing samples.

[0062] For ease of understanding, the following example uses the region where the first sample transfer bit is set in the first sample scheduling and transmission module 400 as the transmission track. See example [link to example]. Figure 2-2 As shown, the first sample transfer bit Z can be set on the main transmission channel of this track segment. For example, when this track segment includes a first sub-track and a second sub-track, it can be set on the main channel of either the first or second sub-track, or the first sample transfer bit Z can be set on the main channels of both the first and second sub-tracks respectively. In this example, the first and second sub-tracks of this track segment do not need to have branch channels. See another example. Figure 2-3 As shown, the first sample transfer position Z can also be set on a branch road of this track segment. For example, when this track segment includes a first sub-track and a second sub-track, either the first sub-track or the second sub-track can have a branch road that connects to the main road (such as...). Figure 2-3 The arc-shaped branch channel (the specific shape of the branch channel is not limited here) can be used to set the first sample transfer position Z. Samples to be transferred can enter the branch channel through the main channel and complete the sample transfer on the branch channel; see also, for example, […]. Figure 2-4 As shown, branch roads can also be set on the main roads of the first and second sub-tracks respectively (e.g. Figure 2-4 The two arc-shaped branch channels are used, and a first sample transfer position Z is set on each of these two branch channels. In this embodiment, the second sample transfer position can also be, but is not limited to, the following. Figures 2-2 to 2-4 The settings shown will not be described in detail again.

[0063] The analysis system transmission device 320 is configured to transmit samples from the first sample scheduling transmission module 400 to the sample analyzer 330, which is then configured to analyze and process the samples. Thus, samples transmitted from the first sample scheduling transmission module 400 are transferred to the sample analyzer 330 via the analysis system transmission device 320 for analysis and processing. In some application examples, the samples processed by the sample analyzer 330 can be returned to the first sample scheduling transmission module 400 via the analysis system transmission device 320, and then transferred and scheduled using a sample transfer module. For example, the sample transfer module can transfer the sample to the sample loading / unloading module 311 for retrieval, and / or transfer it to the sample loading / unloading module 311 and then to the second sample scheduling transmission module 500, or directly to the second sample scheduling transmission module 500, and then to the main rail transmission system 200, from which it is transmitted to at least one of the pre-processing system 100, the post-processing system, or other sample analysis systems. In this example, the sample analyzer 330 performs sample analysis and processing, including sample detection and / or various pre-detection treatments such as slide preparation and staining.

[0064] The second sample scheduling and transmission module 500 interfaces with the main rail transmission system 200 to enable sample interaction between them. The second sample scheduling and transmission module 500 has a second sample transfer position for the sample transfer module to transfer samples. In some examples, there can be one second sample transfer position, where the sample transfer module performs both sample grabbing and sample placement on the second sample scheduling and transmission module 500. In other examples, there can be two second sample transfer positions, one for the sample transfer module to grab samples and the other for the sample transfer module to place samples on the second sample scheduling and transmission module 500. Thus, on the one hand, samples from the TLA preprocessing system 100, postprocessing system, or other sample analysis system 300 can enter the second sample scheduling and transmission module 500 through the main rail transmission system 200, and then be transferred to the sample loading and unloading module 311 or directly to the first sample scheduling and transmission module 400 using the sample transfer module, thereby realizing the transfer, scheduling, and analysis of samples entering the main rail transmission system 200; similarly, samples that have been analyzed and processed and returned to the first sample scheduling and transmission module 400, as well as samples located in the sample loading and unloading module 311, can also be transferred to the second sample scheduling and transmission module 500 through the sample transfer module, and then enter the main rail transmission system 200 through the second sample scheduling and transmission module 500, and be transported to the preprocessing system 100 or other sample analysis system 300. On the other hand, the samples loaded by the sample loading device 310 of the analysis system can be transferred to the main rail transmission system 200 through the sample transfer module and the second sample scheduling transmission module 500, or they can be transferred to the analysis system transmission device 320 through the first sample scheduling transmission module 400.

[0065] As can be seen from the above examples, the sample analysis system 300 in this embodiment can be connected to the TLA main rail transmission system 200 through the first sample scheduling and transmission module 400 and the second sample scheduling and transmission module 500, which serve as intermediate adapters, thereby improving the compatibility between the sample analysis system 300 and the TLA. Furthermore, the first sample scheduling and transmission module 400 and the second sample scheduling and transmission module 500 are decoupled, and sample interaction between them is achieved through the sample transfer module. The first sample scheduling and transmission module 400 is more easily adapted to the analysis system transmission device 320 of the sample analysis system 300, and the second sample scheduling and transmission module 500 is also more easily adapted to the TLA main rail transmission system 200. During the adaptation process, there is no need to worry about the adaptation problem between the first sample scheduling and transmission module 400 and the second sample scheduling and transmission module 500, and there is no strong connection requirement between the first sample scheduling and transmission module 400 and the second sample scheduling and transmission module 500. Therefore, the flexibility and compatibility of the sample analysis system 300 and the TLA can be further improved.

[0066] Furthermore, due to the inclusion of the sample loading / unloading module 311 and the sample transfer module, the sample loading device 310 of the analysis system possesses independent sample loading and scheduling functions. After the sample analysis system 300 is connected to the TLA through the sample loading device 310, it can achieve, but is not limited to, the following functions:

[0067] The sample loaded through the sample loading device 310 of the sample analysis system 300 has at least one of the following transport paths:

[0068] The samples are transmitted to their corresponding sample analyzers via the first sample scheduling and transmission module 400 and the analysis system transmission device 320 for analysis and processing by the sample analyzers.

[0069] The samples are transmitted to other sample analysis systems of TLA via the second sample scheduling and transmission module 500 and the main rail transmission system 200.

[0070] The samples are transmitted to the TLA preprocessing system 100 and / or postprocessing system via the second sample scheduling and transmission module 500 and the main rail transmission system 200.

[0071] The second sample scheduling and transmission module 500 of the sample loading device 310 of the sample analysis system 300 can also receive samples from the main rail transmission system 200, and the received samples may have at least one of the following processing methods, but not limited to:

[0072] The received sample is carried in its sample loading and unloading module 311;

[0073] The samples are transmitted to their corresponding sample analyzers via the first sample scheduling and transmission module 400 and the analysis system transmission device 320 for analysis and processing by the sample analyzers.

[0074] The samples are transmitted to other sample analysis systems of TLA via the second sample scheduling and transmission module 500 and the main rail transmission system 200; or via the first sample scheduling and transmission module 400, the analysis system transmission device 320, the second sample scheduling and transmission module 500, and the main rail transmission system 200.

[0075] The samples are transmitted to the TLA preprocessing system 100 and / or postprocessing system via the second sample scheduling transmission module 500 and the main rail transmission system 200; or, they are transmitted to the TLA preprocessing system 100 and / or postprocessing system via the first sample scheduling transmission module 400, the analysis system transmission device 320, the second sample scheduling transmission module 500, and the main rail transmission system 200.

[0076] As can be seen, the TLA provided in this embodiment has higher fault tolerance and better reliability, including but not limited to:

[0077] Under the condition of failure of the TLA preprocessing system 100, the sample loading and scheduling can be realized by the sample loading device 310 of the sample analysis system 300, that is, the sample loading device 310 of the analysis system can replace the preprocessing system 100.

[0078] Even if the analysis system transmission device 320 of the sample analysis system 300 fails, its analysis system loading device 310 can still load and schedule samples normally, serving as the sample input and output module of TLA.

[0079] Under the condition of a failure in the main rail transmission system 200, the sample loading device 310 of the sample analysis system 300 can, on the one hand, operate offline (i.e. disconnected from the main rail transmission system) to normally load and schedule samples within the sample analysis system; on the other hand, it can also be combined with the part of the main rail transmission system 200 that is not malfunctioning and is connected to the sample loading device of the sample analysis system 300 to transfer samples through the malfunctioning part of the main rail system to at least one of other sample analysis systems, preprocessing systems, and postprocessing systems.

[0080] It is evident that the TLA provided in this embodiment exhibits better disaster prevention capabilities when the above-described failures occur, and can better meet the needs of TAT and some urgent sample testing requirements. Furthermore, in some application scenarios of this embodiment, the sample loading device of the sample analysis system can also work in parallel with the TLA's preprocessing system to achieve parallel sample loading, thereby improving the sample processing throughput of the TLA.

[0081] In some embodiments, the sample loading and unloading module 311 includes a sample loading carrier for loading samples, and the first sample scheduling and transmission module 400 and the second sample scheduling and transmission module 500 respectively use the first sample transmission carrier 1 and the second sample transmission carrier 2 for sample transmission. At least one of the first sample transmission carrier 1 and the second sample transmission carrier 2 is a single-tube transmission carrier capable of holding only one sample tube. Alternatively, at least one of the first sample transmission carrier 1 and the second sample transmission carrier 2 can also be a multi-tube transmission carrier capable of simultaneously accommodating at least two sample tubes.

[0082] In some application examples, at least two of the sample loading vehicle, the first sample transmission vehicle 1, and the second sample transmission vehicle 2 are the same physical vehicle or different physical vehicles. For example, when the sample loading vehicle and the first sample transmission vehicle 1 are different physical vehicles, when transferring samples from the sample loading / unloading module 311 to the first sample scheduling and transmission module 400, the first sample transmission vehicle 1 with an empty sample tube position can be pre-configured in the first sample transfer position of the first sample scheduling and transmission module 400, and the sample transfer module will then transfer the sample tubes placed in the sample loading vehicle to the empty sample tube position of the first sample transmission vehicle 1; similarly, when transferring samples from the first sample scheduling and transmission module 400 to the sample loading / unloading module 311, a sample loading vehicle with an empty sample tube position can be configured in the sample loading / unloading module 311, and the sample transfer module will then transfer the sample tubes located in the corresponding first sample transmission vehicle 1 to the empty sample tube position of the sample loading vehicle. When the sample loading carrier and the first sample transmission carrier 1 are the same physical carrier, the sample tubes and the carrier loading the sample tubes can be transferred together between the sample loading / unloading module 311 and the first sample scheduling and transmission module 400 using the sample transfer module. This eliminates the need for a separate sample loading carrier or the first sample transmission carrier 1 with available sample tube positions, making sample scheduling control more convenient. Therefore, in the preferred embodiment of this example, the sample loading carrier and the first sample transmission carrier 1 can use the same physical carrier.

[0083] Similarly, in some application examples, when the second sample transport vehicle 2 and the sample loading vehicle are different physical vehicles, when transferring samples from the sample loading / unloading module 311 to the second sample scheduling and transport module 500, the second sample transport vehicle 2 with an empty sample tube position can be pre-configured in the second sample transfer position of the second sample scheduling and transport module 500, and the sample transfer module will transfer the sample tubes placed in the sample loading vehicle to the empty sample tube position of the second sample transport vehicle 2; when transferring samples from the second sample scheduling and transport module 500 to the sample loading / unloading module 311, a sample loading vehicle with an empty sample tube position can be configured in the sample loading / unloading module 311, and the sample transfer module will transfer the sample tubes located in the corresponding second sample transport vehicle 2 to the empty sample tube position of the sample loading vehicle. When the sample loading carrier and the second sample transmission carrier 2 are the same physical carrier, the sample transfer module can be used to transfer the sample tube and the carrier loading the sample tube together between the sample loading / unloading module 311 and the second sample scheduling and transmission module 500, without the need to separately configure a sample loading carrier or the second sample transmission carrier 2 with empty sample tube positions, making sample scheduling control more convenient. Therefore, in the preferred embodiment of this example, the sample loading carrier and the second sample transmission carrier 2 use the same physical carrier. Similarly, in a further preferred embodiment of this example, both the first sample transmission carrier 1 and the second sample transmission carrier 2 use the same physical carrier. Thus, when it is necessary to directly schedule samples between the first sample scheduling and transmission module 400 and the second sample scheduling and transmission module 500, the sample transfer module can be used to transfer the sample tube and the carrier loading the sample tube together between the first sample scheduling and transmission module 400 and the second sample scheduling and transmission module 500, without the need to separately configure a first sample transmission carrier 1 or a second sample transmission carrier 2 with empty sample tube positions, making sample scheduling control more convenient. In a more preferred embodiment of this example, the sample loading vehicle, the first sample transmission vehicle 1, and the second sample transmission vehicle 2 are all the same physical vehicle.

[0084] In some embodiments, the first sample transport carrier 1 and the third sample transport carrier used by the analysis system transport device 320 are different physical carriers. Optionally, a first transfer module is provided between the first sample scheduling and transport module 400 and the analysis system transport device 320. The first transfer module is used to transfer sample tubes between the first sample transport carrier 1 and the third sample transport carrier. The side of the first sample scheduling and transport module 400 that receives sample tubes needs to be configured with either the first sample transport carrier 1 or the third sample transport carrier with available sample positions. In this example, the first transfer module can reuse the sample transfer module, or it can use other modules that implement sample transfer that are independent of the sample transfer module.

[0085] In some embodiments, the first sample transfer carrier 1 and the third sample transfer carrier are the same physical carrier. Between the first sample scheduling and transfer module 400 and the analysis system transfer device 320, the sample tube and the carrier holding the sample tube can flow directly without requiring a separate first transfer module. This makes sample transfer and scheduling more convenient and faster. Therefore, in the preferred embodiment of this example, the first sample transfer carrier 1 and the third sample transfer carrier are the same physical carrier. The first sample transfer carrier 1 can be a single-tube transfer carrier that can only hold one sample tube, such as... Figure 2-1 As shown. Of course, the first sample transport carrier 1 can also be a multi-tube transport carrier capable of accommodating at least two sample tubes simultaneously, such as... Figure 3 As shown.

[0086] In some implementations, the second sample transport vehicle 2 and the fourth sample transport vehicle used in the main rail transport system 200 are the same physical vehicle. Optionally, a second transfer module can be set between the second sample scheduling and transport module 500 and the main rail transport system 200. The second transfer module is used to transfer sample tubes between the second sample transport vehicle 2 and the fourth sample transport vehicle. The side of the second sample scheduling and transport module 500 that receives sample tubes needs to be configured with either the second sample transport vehicle 2 or the fourth sample transport vehicle with available sample positions. In this example, the second transfer module can reuse the sample transfer module, or it can use other modules that implement sample transfer that are independent of the sample transfer module.

[0087] In other embodiments, the second sample transport vehicle 2 and the fourth sample transport vehicle are the same physical vehicle. In this case, the sample tube and the vehicle carrying the sample tube can flow directly between the second sample scheduling and transport module 500 and the main rail transport system 200 without the need for a separate second transfer module. This makes sample transfer and scheduling more convenient and faster. Therefore, in the preferred embodiment of this example, the second sample transport vehicle 2 and the fourth sample transport vehicle are the same physical vehicle.

[0088] In some embodiments of this example, the sample loading device body is provided with a centrifugation module, which includes a centrifuge (e.g., Figure 5(As indicated by label A in the diagram) and a centrifuge adapter, the centrifuge is used to centrifuge samples, and the centrifuge adapter serves as a carrier for the sample tubes to be centrifuged, placed inside the centrifuge for the centrifugation operation. In this example, the sample transfer module is also configured to transfer the sample to the centrifuge adapter, transfer the centrifuge adapter to the centrifuge, and transfer the centrifuge adapter from the centrifuge to the sample loading / unloading module 311. Of course, it should be understood that in other examples, an adapter transfer module independent of the sample transfer module can be additionally provided to realize the above transfer path of the adapter. In some application examples of this embodiment, at least two of the sample loading carrier, the first sample transmission carrier 1, and the centrifuge adapter are the same physical carrier or different physical carriers. The relevant implementations where the sample loading carrier and the first sample transmission carrier 1 are the same physical carrier or different physical carriers are as described above and will not be repeated. In some application scenarios, the sample loading carrier and the centrifuge adapter are set as different physical carriers. When transferring samples from the centrifuge module to the sample loading / unloading module 311, a sample loading carrier with empty sample positions is configured within the sample loading / unloading module 311. Then, the sample transfer module is used to transfer the sample tubes located in the centrifuge adapter to the corresponding empty sample positions of the sample loading carrier. When transferring samples from the sample loading / unloading module 311 to the centrifuge module, an empty centrifuge adapter needs to be configured within the centrifuge module (the centrifuge adapter can be transferred and configured using the sample transfer module). Then, the sample transfer module is used to transfer the corresponding sample tubes placed in the sample loading carrier to the centrifuge adapter. In other application scenarios, the loading carrier and the centrifuge adapter are set as the same physical carrier. In this case, the sample transfer module can be used to transfer the sample tubes and the carrier holding the sample tubes together between the sample loading / unloading module 311 and the centrifuge module, eliminating the need to separately configure a sample loading carrier with empty sample positions and a centrifuge adapter. This makes sample transfer and scheduling more convenient and faster. Therefore, in the preferred embodiment of this example, the sample loading carrier and the centrifuge adapter are the same physical carrier.

[0089] In some application examples, the first sample transport carrier 1 and the centrifuge adapter are set as different physical carriers. When transferring samples from the centrifuge module to the first sample scheduling and transport module 400, the first sample transport carrier 1 with an empty sample position is configured within the first sample scheduling and transport module 400. Then, the sample transfer module is used to transfer the sample tube located in the centrifuge adapter to the corresponding empty sample position of the first sample transport carrier 1. When transferring samples from the first sample scheduling and transport module 400 to the centrifuge module, an empty centrifuge adapter needs to be configured within the centrifuge module (the centrifuge adapter can be transferred and configured using the sample transfer module). Then, the sample transfer module is used to transfer the corresponding sample tube placed in the corresponding first sample transport carrier 1 to the centrifuge adapter. In other application examples, the first sample transport carrier 1 and the centrifuge adapter are set as the same physical carrier. In this case, the sample transfer module can be used to transfer the sample tube and the carrier containing the sample tube together between the first sample scheduling and transport module 400 and the centrifuge module, without the need to separately configure the first sample transport carrier 1 with an empty sample position and the centrifuge adapter, making sample transfer and scheduling more convenient and faster. Therefore, in the preferred embodiment of this example, the first sample transfer carrier 1 and the centrifuge adapter are the same physical carrier. At this time, the sample transfer module is also configured to transfer the centrifuge adapter from the centrifuge or from the sample loading and unloading module 311 to the first sample scheduling and transfer module 400.

[0090] In some other embodiments, although the first sample transport carrier 1 and the centrifuge adapter are different physical carriers, the first sample scheduling and transport module 400 and the analysis system transport device 320 can be configured to transport the centrifuge adapter. In this case, the sample transfer module is used to transfer the sample tube into the centrifuge adapter for centrifugation, and the centrifuged sample tube and the centrifuge adapter are then transferred together to the first sample scheduling and transport module 400. Similarly, in some other embodiments, although the second sample transport carrier 2 and the centrifuge adapter are different physical carriers, the second sample scheduling and transport module 500 and the main rail transport system 200 can be configured to transport the centrifuge adapter. In this case, the sample transfer module is used to transfer the sample tube into the centrifuge adapter for centrifugation, and the centrifuged sample tube and the centrifuge adapter are then transferred together to the second sample scheduling and transport module 500.

[0091] In some other embodiments, the sample loading / unloading module 311 is used to load or unload samples. In this embodiment, the sample loading / unloading module 311 is provided with a sample loading carrier. The sample loading carrier can be a movable carrier or a fixed carrier that is not movable. When the sample loading carrier is a movable carrier, the sample loading carrier carrying the sample tube to be loaded is loaded into the sample loading / unloading module, or the sample loading carrier carrying the sample tube to be unloaded is unloaded from the sample loading / unloading module; when the sample loading carrier is a fixed carrier fixed in the sample loading / unloading module, the sample tube to be loaded is loaded into the sample loading carrier, or the sample tube to be unloaded is unloaded from the sample loading carrier.

[0092] In this embodiment, the sample transfer module is used at least to realize sample transfer between the sample loading / unloading module 311 and the first sample scheduling and transmission module 400, and between the sample loading / unloading module 311 and the second sample scheduling and transmission module 500. For example, the sample transfer module can complete the grabbing and transfer of single tube samples or sample carriers, including but not limited to transfers between different positions of the loading / unloading carriers of the sample loading / unloading module 311, and / or between the sample loading / unloading module 311 and the first sample scheduling and transmission module 400, and / or between the sample loading / unloading module 311 and the second sample scheduling and transmission module 500, and / or between the first sample transmission carrier 1 and the second sample transmission carrier 2, and / or between different first sample transmission carriers 1 within the first sample scheduling and transmission module 400 and between different positions of the same first sample transmission carrier 1 (when the first sample transmission carrier 1 is a multi-tube transmission carrier), and / or between different second sample transmission carriers 2 within the second sample scheduling and transmission module 500, and between different positions of the same second sample transmission carrier 2 (when the second sample transmission carrier 2 is a multi-tube transmission carrier). The sample transfer module can be implemented in various existing ways. In this embodiment, the sample transfer module is a three-dimensional moving manipulator set on the sample device body, and can be set as an extended manipulator as needed. The sample transfer of multiple sample positions can be realized by a single manipulator. It has a simple structure and control, low cost, and high integration.

[0093] In some embodiments of this example, the sample loading device 310 of the analysis system further includes a sample storage module (not shown in the figure). The sample storage module is provided with a sample storage carrier for storing sample tubes. The sample storage module is used to buffer samples, and the area where the sample storage module is located is inaccessible to operators. For example, the sample storage module can be an independent area within the sample loading and unloading module 311, or it can be an area within the sample loading and unloading module 310 of the analysis system that is independent of the sample loading and unloading module 311 and used to buffer samples.

[0094] In some embodiments of this example, the first sample scheduling and transmission module 400 is provided with a first interface 401 and a second interface 402. The first interface 401 and the second interface 402 are located at one end of the first sample scheduling and transmission module 400 near the analysis system transmission device 320. The first interface 401 is used to receive the first sample transmission carrier 1 input from the analysis system transmission device 320; the second interface 402 is used to output the first sample transmission carrier 1 to the analysis system transmission device 320. For example, as... Figure 2-1 As shown, when the first sample transmission carrier 1 uses a single-tube transmission carrier, considering the high scheduling frequency of the single-tube transmission carrier, it is advisable to set the first interface 401 and the second interface 402 to be independent of each other. In this case, the first sample scheduling transmission module 400 includes a first sample scheduling track 410 and a second sample scheduling track 420 with opposite transmission directions. The analysis system transmission device 320 includes a first analysis system transmission track 321 and a second analysis system transmission track 322 with opposite transmission directions. The first sample scheduling track 410 and the first analysis system transmission track 321 have the same transmission direction and are both connected to the first interface 401. The second sample scheduling track 420 and the second analysis system transmission track 322 have the same transmission direction and are both connected to the second interface 402. Thus, the sample transfer module can directly transfer the first sample transport carrier 1, which contains the sample tube to be tested, from the sample loading and unloading module 311 to the second sample scheduling track 420. The first sample transport carrier 1 is transferred to the second analysis system transport track 322 via the second interface 402 and enters the corresponding sample analyzer 330 for testing. Then, after transferring the first sample transport carrier 1 to the first analysis system transport track 321, it is transferred to the second sample scheduling track 420 via the first interface 401, and then transferred to the sample loading and unloading module 311 via the sample transfer module. Figure 3 As shown, when the first sample transmission carrier 1 uses a multi-tube transmission carrier, considering the large loading capacity and low scheduling frequency of the first sample transmission carrier 1, it is preferable to set the first interface 401 and the second interface 402 to overlap. That is, at this time, there is only one interface between the first sample scheduling transmission module 400 and the analysis system transmission device 320, which makes the structure more compact and simpler, and is more conducive to improving the system throughput. In this example, both the first sample scheduling transmission module 400 and the analysis system transmission device 320 use bidirectional transmission tracks with opposite transmission directions.

[0095] In some embodiments, after the first sample transport carrier 1 is dispatched to the analysis system transport device 320, the analysis system transport device 320 transfers the first sample transport carrier 1 to a position that can be grasped by the gripper inside the sample analyzer 330, and then the gripper of the sample analyzer 330 transfers it to the sampling position of the sample analyzer 330, instead of the analysis system transport device 320 transferring the first sample transport carrier 1 and the sample to the sampling position of the sample analyzer 330. Figure 4 As shown. In other embodiments, the analysis system transmission device 320 can also directly transfer the first sample transmission carrier 1 and the sample to the sampling position of the sample analyzer 330 for sampling, such as... Figure 5 As shown.

[0096] It should be noted that in related technologies, a single-tube transfer interface module is additionally set between the main rail transfer system 200 and the analysis system transfer device 320. The pretreatment system 100 transfers samples through the sample transfer carrier and the main rail transfer system 200 to the additional single-tube transfer interface module. Then, the single-tube sample is transferred from the sample transfer carrier of the main rail transfer system 200 to the sample transfer carrier of the sample analysis system via the single-tube transfer interface module for subsequent processing. In this related technology, the samples to be tested are all loaded through the pretreatment system 100 and transferred to the sample analysis system via the main rail transfer system 200. If either the pretreatment system 100 or the main rail transfer system 200 fails, the entire TLA will be paralyzed, which also presents the technical problem to be solved in the background of this invention. Furthermore, the additional single-tube transfer interface module in this related technology increases the footprint and cost of the TLA. The additional sample tube transfer module in the single-tube transfer interface module also increases the risk of TLA failure.

[0097] In a preferred embodiment of this example, the second sample scheduling and transmission module 500 uses the same second sample transmission carrier 2 as the main rail transmission system 200 for sample transmission. This eliminates the need for a single-tube transfer interface module between the main rail transmission system 200 and the sample analysis system 300. For example, the second sample transmission carrier 2 can be a single-tube transmission carrier capable of holding only one sample tube; alternatively, it can be a multi-tube transmission carrier capable of holding at least two sample tubes simultaneously. In this embodiment, the second sample transmission carrier 2 uses a single-tube transmission carrier capable of holding only one sample tube, such as... Figures 2-1 to 3As shown. The second sample scheduling and transmission module 500 is provided with a third interface 501 and a fourth interface 502, which are located at one end of the second sample scheduling and transmission module 500 near the main rail transmission system 200. The third interface 501 is used to receive the second sample transmission carrier 2 input from the main rail transmission system 200, and the fourth interface 502 is used to output the second sample transmission carrier 2 back to the main rail transmission system 200. Considering the high scheduling frequency of the single-tube transmission carrier, in this embodiment, the third interface 501 and the fourth interface 502 are set to be independent of each other. Correspondingly, the second sample scheduling and transmission module 500 includes a third sample scheduling track 510 and a fourth sample scheduling track 520 with opposite transmission directions. The third sample scheduling track 510 is connected to the third interface 503, and the fourth sample scheduling track 520 is connected to the fourth interface 502. Thus, the second sample transport carrier 2, loaded with the sample tube to be tested, is transferred from the main rail transport system 200 to the third sample scheduling track 510 via the third interface 501. The second sample transport carrier 2 is then transferred to the sample loading / unloading module 311 via the sample transfer module. The sample transfer module, the first sample scheduling and transport module 400, and the analysis system transport device 320 are then used to achieve scheduling and testing within the corresponding sample analysis system 300. When the sample loading / unloading module 311 or the sample storage module contains samples that need to be tested in other sample analysis systems 300 or need to be transferred to the pre-processing system 100, the sample transfer module can be used to transfer the sample tube to the empty second sample transport carrier 2 located in the second sample scheduling and transport module 500, or the sample transfer module can be used to transfer the sample tube and the second sample transport carrier 2 containing the sample tube together to the second sample scheduling and transport module 500, and then transported to the main rail transport system 200 via the fourth interface 502.

[0098] As shown in the examples above, the first sample transport vehicle 1 and the second sample transport vehicle 2 can be the same sample transport vehicle, or they can be physically incompatible different sample transport vehicles. Figure 2-1 As shown, the first sample transmission carrier 1 and the second sample transmission carrier 2 are the same sample transmission carriers, and both are single-tube transmission carriers. Figure 3 As shown, the first sample transmission carrier 1 and the second sample transmission carrier 2 are physically incompatible and different sample transmission carriers. Specifically, the first sample transmission carrier 1 is a single-tube transmission carrier, and the second sample transmission carrier 2 is a multi-tube transmission carrier.

[0099] In some embodiments of this example, the system sample loading device 310 includes a housing, and the first sample scheduling and transmission module 400 can be configured in various ways, for example:

[0100] In one example of the setting, a first accommodation area for accommodating the first sample scheduling and transfer module 400 is provided on the main body of the sample loading device. One end of the first sample scheduling and transfer module 400 is fixed to the analysis system transfer device 320 or the sample analyzer 330 corresponding to the analysis system transfer device 320, and the other end extends into the first accommodation area. In this embodiment, the first sample scheduling and transfer module 400 can be regarded as a part of the analysis system transfer device 320. The positioning mechanism and the like in the first sample scheduling and transfer module 400 that are matched with the sample transfer module can be uniformly provided, uniformly controlled, and uniformly powered by the analysis system transfer device 320. Of course, the first sample scheduling and transfer module 400 can also not be regarded as a part of the analysis system transfer device 320. Specifically, in this embodiment, the first sample scheduling and transfer module 400 and the analysis system transfer device 320 can be integrally provided or non-integrally provided. When the first sample scheduling and transfer module 400 and the analysis system transfer device 320 are non-integrally provided, the first sample scheduling and transfer module 400 is detachably connected to the analysis system transfer device 320 and the sample analyzer 330.

[0101] In another configuration example, the first sample scheduling and transmission module 400 is fixed within the sample loading device body. One end of the first sample scheduling and transmission module 400 is exposed through a corresponding opening in the housing to interface with the analysis system transmission device 320. That is, in this case, the first sample scheduling and transmission module 400 is structurally and controllably part of the system sample loading device 310. In a preferred embodiment of this example, when the first sample scheduling and transmission module 400 is fixed within the housing, the system sample loading device 310 further includes a first height adjustment module configured to adjust the height of the first sample scheduling and transmission module 400. Specifically, the height of the first sample scheduling and transmission module 400 refers to the distance of the first sample scheduling and transmission module 400 relative to the mounting surface (e.g., the ground). The first height adjustment module can be implemented in various ways. For example, a stepped platform can be set at the location where the first sample scheduling and transmission module 400 is installed in the system sample loading device 310, and the height can be adjusted by installing the first sample scheduling and transmission module 400 on different steps. Alternatively, the height of the first sample scheduling and transmission module 400 can be adjusted by adding or removing shims. Of course, a height adjustment mechanism (such as a threaded screw mechanism) can also be set inside the system sample loading device 310 to adjust the height of the first sample scheduling and transmission module 400; these will not be elaborated further. Specifically, the first sample scheduling and transmission module 400 is preferably fixed inside the system sample loading device 310, and preferably it is detachably installed inside the housing of the system sample loading device 310, which facilitates flexible selection of whether to add the system sample loading device 310 according to user needs. Of course, the first sample scheduling and transmission module 400 can be installed in the housing of the system sample loading device 310 in a non-detachable manner. Specifically, the system sample loading device 310 may be fixed to the main body (e.g., frame) of the system sample loading device 310.

[0102] In yet another setup example, such as Figure 6As shown, the first sample scheduling and transmission module 400 can also be configured as a separate unit comprising a first sample scheduling submodule 430 and a second sample scheduling submodule 440, with the sample loading device body having a second receiving area for accommodating the second sample scheduling submodule 440. The first sample scheduling submodule 430 is fixedly disposed within the sample loading device body, and one end of the second sample scheduling submodule 440 is fixed to the analysis system transmission device 320 or the sample analyzer 330 corresponding to the analysis system transmission device 320, while the other end extends into the second receiving area and docks with the first sample scheduling submodule 430. In this embodiment, one end of the first sample scheduling submodule 430 docks with the second sample scheduling submodule 440 through the second receiving area. That is, at this time, the first sample scheduling submodule 430 is part of the system sample loading device 310 both structurally and in terms of control. In a preferred embodiment of this invention, when the first sample scheduling submodule 430 is fixed within the housing, the system sample loading device 310 further includes a second height adjustment module configured to adjust the height of the first sample scheduling submodule 430. Specifically, the height of the first sample scheduling submodule 430 refers to the distance of the first sample scheduling submodule 430 relative to the mounting surface (e.g., the ground). The second height adjustment module can be implemented in various existing ways. For example, a step can be set at the location where the first sample scheduling submodule 430 is installed in the system sample loading device 310, and the height can be adjusted by installing the first sample scheduling submodule 430 on different steps; another way is to adjust the height of the first sample scheduling submodule 430 by adding or removing shims; of course, a height adjustment mechanism (such as a threaded screw mechanism) can also be set in the system sample loading device 310 to adjust the height of the first sample scheduling submodule 430; these will not be elaborated further. Specifically, the first sample scheduling submodule 430 is preferably fixed within the system sample loading device 310, or preferably detachably installed within the housing of the system sample loading device 310, allowing for flexible selection of whether to add the system sample loading device 310 to the instrument according to user needs. Alternatively, the first sample scheduling submodule 430 can be non-detachably installed within the housing of the system sample loading device 310. Specifically, the system sample loading device 310 can be fixed to the main body (e.g., frame) of the system sample loading device 310. Furthermore, in this embodiment, the second sample scheduling submodule 440 can be incorporated as part of the analysis system transmission device 320. Specifically, the positioning mechanism and other components within the second sample scheduling submodule 440 that are compatible with the sample transfer module can be uniformly provided, controlled, and powered by the analysis system transmission device 320.Specifically, in this embodiment, the second sample scheduling submodule 440 and the analysis system transmission device 320 can be integrated or not integrated. When the second sample scheduling submodule 440 and the analysis system transmission device 320 are not integrated, the second sample scheduling submodule 440, the analysis system transmission device 320 and the corresponding sample analyzer 330 can be detachably connected.

[0103] In one configuration example, the system sample loading device 310 includes a housing, and the second sample scheduling and transmission module 500 can be configured in various ways, for example:

[0104] In one configuration example, the sample loading device body has a third accommodating area for accommodating the second sample scheduling and transmission module 500. One end of the second sample scheduling and transmission module 500 is fixed to the main rail transmission system 200, and the other end extends into the third accommodating area. In this embodiment, the second sample scheduling and transmission module 500 can be considered as part of the main rail transmission system 200. Positioning mechanisms and other components within the second sample scheduling and transmission module 500 that are compatible with the sample transfer module can be uniformly provided, controlled, and powered by the main rail transmission system 200. Alternatively, the second sample scheduling and transmission module 500 can be considered not as part of the main rail transmission system 200. Specifically, in this embodiment, the second sample scheduling and transmission module 500 and the main rail transmission system 200 can be integrally configured or non-integrated. When the second sample scheduling and transmission module 500 and the main rail transmission system 200 are not integrally configured, they are detachably connected.

[0105] In another configuration example, the second sample scheduling and transmission module 500 is fixedly mounted within the sample loading device body. One end of the second sample scheduling and transmission module 500 is exposed through a corresponding opening in the housing to interface with the main rail transmission system 200. That is, in this case, the second sample scheduling and transmission module 500 is structurally and controllably part of the system sample loading device 310. In a preferred embodiment of this example, when the second sample scheduling and transmission module 500 is fixed within the housing, the system sample loading device 310 further includes a third height adjustment module configured to adjust the height of the second sample scheduling and transmission module 500. Specifically, the height of the second sample scheduling and transmission module 500 refers to the distance of the second sample scheduling and transmission module 500 relative to the mounting surface (e.g., the ground). The third height adjustment module can be implemented in various ways. For example, a step can be set at the location where the second sample scheduling and transmission module 500 is installed in the system sample loading device 310, and the height can be adjusted by installing the second sample scheduling and transmission module 500 on different steps. Alternatively, the height of the second sample scheduling and transmission module 500 can be adjusted by adding or removing shims. Of course, a height adjustment mechanism (such as a threaded screw mechanism) can also be set inside the system sample loading device 310 to adjust the height of the second sample scheduling and transmission module 500; these will not be elaborated further. Specifically, the second sample scheduling and transmission module 500 is preferably fixed inside the system sample loading device 310, and preferably it is detachably installed inside the housing of the system sample loading device 310, which facilitates flexible selection of whether to add the system sample loading device 310 according to user needs. Of course, the second sample scheduling and transmission module 500 can be installed in the housing of the system sample loading device 310 in a non-detachable manner. Specifically, the system sample loading device 310 may be fixed to the main body (e.g., frame) of the system sample loading device 310.

[0106] In yet another setup example, such as Figure 6As shown, the second sample scheduling and transmission module 500 can also be configured as a separate unit comprising a third sample scheduling submodule 530 and a fourth sample scheduling submodule 540, which are independent of each other. The sample loading device body is provided with a fourth receiving area to accommodate the fourth sample scheduling submodule 540. The third sample scheduling submodule 530 is fixedly disposed within the sample loading device body, and one end of the fourth sample scheduling submodule 540 is fixed to the main rail transmission system 200, while the other end extends into the fourth receiving area and docks with the third sample scheduling submodule 530. In this embodiment, one end of the third sample scheduling submodule 530 docks with the fourth sample scheduling submodule 540 through the fourth receiving area. That is, at this time, the third sample scheduling submodule 530 is part of the system sample loading device 310, both structurally and in terms of control. In a preferred embodiment of this example, when the third sample scheduling submodule 530 is fixed within the housing, the system sample loading device 310 further includes a fourth height adjustment module configured to adjust the height of the third sample scheduling submodule 530. Specifically, the height of the third sample scheduling submodule 530 refers to the distance of the third sample scheduling submodule 530 relative to the mounting surface (e.g., the ground). The fourth height adjustment module can be implemented in various existing ways. For example, steps can be set at the location where the third sample scheduling submodule 530 is installed in the system sample loading device 310, and the height can be adjusted by installing the third sample scheduling submodule 530 on different steps. Alternatively, the height of the third sample scheduling submodule 530 can be adjusted by adding or removing shims. Of course, a height adjustment mechanism (such as a threaded screw mechanism) can also be set within the system sample loading device 310 to adjust the height of the third sample scheduling submodule 530; these details will not be elaborated further. Specifically, the third sample scheduling submodule 530 is preferably fixed within the system sample loading device 310, or preferably detachably installed within the housing of the system sample loading device 310, allowing for flexible selection of whether to add the system sample loading device 310 to the instrument according to user needs. Alternatively, the third sample scheduling submodule 530 can be non-detachably installed within the housing of the system sample loading device 310. Specifically, the system sample loading device 310 can be fixed to the main body (e.g., frame) of the system sample loading device 310. Furthermore, in this embodiment, the fourth sample scheduling submodule 540 can be considered part of the main rail transmission system 200. Specifically, the positioning mechanism and other components within the fourth sample scheduling submodule 540 that are compatible with the sample transfer module can be uniformly provided, controlled, and powered by the main rail transmission system 200. Alternatively, the fourth sample scheduling submodule 540 can be considered not part of the main rail transmission system 200.Specifically, in this embodiment, the fourth sample scheduling submodule 540 can be integrated with the main rail transmission system 200, or they can be separate. When the fourth sample scheduling submodule 540 is not integrated with the main rail transmission system 200, the fourth sample scheduling submodule 540 can be detachably connected to the main rail transmission system 200 and the corresponding sample analyzer 330.

[0107] like Figures 2-1 to 5 As shown, in some examples of this embodiment, the first sample scheduling and transmission module 400 and the second sample scheduling and transmission module 500 are disposed on different sides of the sample loading device body. Specifically, one first sample scheduling and transmission module 400 and one second sample scheduling and transmission module 500 are each disposed on opposite sides of the sample loading device body. In other embodiments, the analytical system sample loading device 310 may also include one second sample scheduling and transmission module 500 and at least two first sample scheduling and transmission modules 400, with different first sample scheduling and transmission modules 400 docked with a different analytical system transmission device 320. That is, in this embodiment, the same analytical system sample loading device 310 can connect to at least two system analytical devices, and the analytical system sample loading device 310 can serve as a sample transfer and scheduling center for at least two system analytical devices. In an optional embodiment, such as Figure 7 As shown, the sample analysis system includes two system analysis devices. Correspondingly, the sample loading device 310 of the analysis system includes one second sample scheduling and transmission module 500 and two first sample scheduling and transmission modules 400. The two first sample scheduling and transmission modules 400 are respectively connected to the analysis system transmission devices 320 of the two system analysis devices. To avoid positional interference between the two first sample scheduling and transmission modules 400 and between the two system analysis devices, preferably, the two first sample scheduling and transmission modules are arranged on opposite sides of the sample loading device body. In another embodiment, as... Figure 8 As shown, the sample loading device 310 of the analysis system includes a second sample scheduling and transmission module 500 and three first sample scheduling and transmission modules 400. The three first sample scheduling and transmission modules 400 are respectively connected to the analysis system transmission devices 320 of the three system analysis devices. In order to avoid positional interference between the second sample scheduling and transmission module 500 and the three first sample scheduling and transmission modules 400, preferably, the second sample scheduling and transmission module 500 and the three first sample scheduling and transmission modules 400 are respectively arranged on the four sides of the sample loading device body.

[0108] Optionally, in the sample analysis system, when the system analysis device includes at least two sample analyzers 330 arranged sequentially, the analysis system transmission device 320 includes analysis system transmission modules 323 that correspond one-to-one with each sample analyzer 330 and support bidirectional transmission. The analysis system transmission modules 323 are sequentially connected and operate independently. Except for the last analysis system transmission module 323, each of the other analysis system transmission modules 323 is equipped with a first reversing element for changing the sample transmission direction. The first reversing element is used to switch the sample between the two transmission directions of the analysis system transmission module 323. Thus, in one application scenario: such as... Figure 9 As shown, among adjacent sample analyzers A and B, sample analyzer A, which is closer to the sample loading device 310 of the analysis system, and its corresponding analysis system transmission module a are operating normally. Sample analyzer B, which is farther from the sample loading device 310, has a faulty corresponding analysis system transmission module b. Therefore, the analysis system transmission module a of sample analyzer A, which is closer to the sample loading device 310, can also form a sample transfer loop with the first sample scheduling transmission module 400, and can receive and process samples loaded from the sample loading device 310 of the analysis system. In another application scenario: such as... Figure 5 As shown, among two adjacent sample analyzers A and B, assuming that sample analyzer A is faulty, but its corresponding analysis system transmission module a is normal, and sample analyzer B and its corresponding sub-analysis system transmission module b are normal, then at least analysis system transmission module b can form a sample flow loop with the first sample scheduling transmission module 400 through analysis system transmission module a, so that sample analyzer B and the subsequent sample analyzers 330 can still receive and process samples loaded from the analysis system loading device 310.

[0109] like Figure 10 As shown, in some embodiments of this example, the main rail transport system 200 includes multiple main rail units 210 with first and second main rails. Each main rail unit 210 also includes a second reversing component that moves samples between the first and second main rails. Each main rail unit 210 operates independently, and the sample analysis system 300 is connected to one of the main rail units 210. Thus, when a section of the main rail unit 210 fails, the unaffected preprocessing system 100, the main rail unit 210, and the corresponding sample analysis system 300 located upstream of the failed main rail unit 210 (the side where the preprocessing system 100 is located is upstream) can still form a sample flow loop and operate normally; similarly, the unaffected main rail unit 210 located downstream of the failed main rail unit 210 and the corresponding sample analysis system 300 can still form a sample flow loop and operate normally.

[0110] In this embodiment, the sample holder 310 on the system also includes a drawer module. The sample loading and unloading module 311 is composed of at least one drawer module, wherein the drawer can be a manually pulled drawer or an electrically controlled drawer. In a preferred embodiment, the pulling direction of the drawer module is perpendicular to the transmission direction of the analysis system transmission device 320. The drawer module is located on two opposite or adjacent sides of the sample holder 310 on the side where the extraction port is located and the side where the analysis system transmission device 320 is located, to avoid interference. Specifically, the sample loading and unloading module 311 includes at least one of a sample buffer area, an emergency sample carrying area, a retest sample carrying area, and an abnormal sample carrying area. Multiple drawers can also be provided, and different drawers can load and unload different samples; that is, drawers can be used to load ordinary samples, emergency samples, retest samples, or abnormal samples. Specifically, abnormal samples include samples with incorrect sample type, no barcode, no barcode information, no test information, etc.

[0111] In a preferred embodiment of this invention, each sample analysis system 300 is arranged on the same side of the main rail transmission system 200, which reduces space occupation and facilitates operation. Of course, it should be understood that each sample analysis system 300 can also be arranged on both sides of the main rail transmission system 200. The resulting overall layout can be linear, L-shaped, square-shaped, herringbone-shaped, etc., and can be flexibly configured according to requirements.

[0112] In a preferred embodiment of this example, the main rail transport system 200 is also connected to a refrigeration device to control the temperature of the samples transported within the main rail transport system 200.

[0113] In a preferred embodiment of this example, the system sample loading device 310 further includes a barcode reading module. The barcode reading module is disposed on the sample transfer module and moves with the sample transfer module. The barcode reading module is used to read at least one of the barcode information and sample feature information of the sample when the sample transfer module transfers the sample. The sample feature information includes at least one of the sample quantity, sample tube shape, sample tube cap color, sample tube cap shape, sample tube size, and sample color.

[0114] In a preferred embodiment of this example, the system sample loading device 310 further includes a panoramic vision module. The panoramic vision module is configured to acquire a panoramic image of the sample loading and unloading module 311, which facilitates sample analysis based on the panoramic image (e.g., which locations contain samples, whether sample placement is abnormal, etc.), thereby improving the control effect during the sample loading stage.

[0115] In a preferred embodiment of this example, the system sample loading device 310 further includes a light source module, which is configured to illuminate the shooting area of ​​at least one of the code reading module and the panoramic vision module to improve the recognition and / or shooting effect.

[0116] In a preferred embodiment of this example, the system sample loading device 310 further includes a first cap-opening module, configured to open the caps of the sample tubes. In a preferred embodiment of this example, the pretreatment system 100 includes a second cap-opening module, configured to open the caps of the sample tubes. Specifically, when the system sample loading device 310 is not equipped with the first cap-opening module or the first cap-opening module malfunctions, the sample scheduling and transmission module 400 is configured to transmit the sample through the main rail transmission system 200 to the second cap-opening module for cap-opening processing.

[0117] In a preferred embodiment of this example, the pretreatment system 100 includes a centrifugation module. When the sample loading device 310 is not equipped with a centrifugation module or the configured centrifugation module malfunctions, the sample scheduling and transmission module 400 is configured to transfer the sample to the centrifugation module of the pretreatment system via the main rail transmission system 200 for centrifugation. Of course, the sample loading device 310 can also perform centrifugation in parallel with the pretreatment system 100, thereby improving centrifugation efficiency.

[0118] Specifically, in this embodiment, the docking method is either connectivity or alignment. Specifically, connectivity means that there is a channel between the two for sample transmission; alignment means that the two are positioned relative to each other, allowing samples to be transferred from one to the other. In this case, various transfer modules (e.g., grippers) can be used to transfer samples between the two aligned devices.

[0119] In this embodiment, the sample analysis system 300 can be set up independently of the preprocessing system 100 and the main rail transmission system 200. That is, the sample analysis system 300 can be an independent product. Its specific implementation method is the same as the specific implementation method of the sample analysis system 300 described above in this embodiment, and will not be repeated here.

[0120] In this embodiment, the system sample loading device 310 can be a standalone product, which can be flexibly configured as needed. The specific implementation of the system sample loading device 310 is the same as the specific implementation of the system sample loading device 310 described above in this embodiment, and will not be repeated here.

[0121] This embodiment also proposes a control method for the TLA as described above, including at least one of the following control steps.

[0122] The control sample transfer module transfers samples from the sample loading / unloading module 311 to the first sample scheduling and transmission module 400, and controls the first sample scheduling and transmission module 400 to deliver the samples to the analysis system transmission device 320, so that the analysis system transmission device 320 can transmit the samples to the corresponding sample analyzer 330, thereby achieving the technical objective of transferring samples from the system sample loading device 310 to the sample analyzer 330 for analysis and processing. Optionally, in some examples, after the sample analysis and processing is completed, the control module can also transfer the samples from the analysis system transmission device 320 to the first sample scheduling and transmission module 400, and control the sample transfer module to transfer the samples from the first sample scheduling and transmission module 400 to the sample loading / unloading module 311. Alternatively, the control module can transfer the samples from the first sample scheduling and transmission module 400 to the sample loading / unloading module 311 and then to the second sample scheduling and transmission module 500, through which they are transferred to the main rail transmission system 200, and then transmitted through the main rail transmission system 200 to at least one of the preprocessing system 100, other sample analysis systems, and postprocessing systems.

[0123] The control sample transfer module transfers samples from the sample loading / unloading module 311 to the second sample scheduling and transmission module 500, so that the second sample scheduling and transmission module 500 can deliver the samples to the main rail transmission system 200, and control the main rail transmission system 200 to transfer the samples to at least one of the pre-processing system 100, the recovery position (e.g., the post-processing system), and other sample analysis systems 300. If the centrifugation module is not installed in the system sample loading device 310 or the centrifugation module is malfunctioning, and the samples need to be centrifuged, the control sample transfer is required to be transferred from the sample loading / unloading module 311 to the pre-processing system 100 through the second sample scheduling and transmission module 500 and the main rail transmission system 200. After the samples are centrifuged using the centrifugation module installed in the pre-processing system 100, the samples are then transferred from the pre-processing system 100 to the main rail transmission system 200. If the first cap-opening module is not configured in the sample loading device 310 or the first cap-opening module malfunctions, it is necessary to control the sample to be transferred from the sample loading and unloading module 311 to the pre-processing system 100 through the second sample scheduling and transmission module 500 and the main rail transmission system 200. After the sample is opened using the second cap-opening module in the pre-processing system 100, the sample is then transferred from the pre-processing system 100 to the main rail transmission system 200. In addition, to facilitate centralized sample retrieval, it is preferable to concentrate the samples for retrieval at the retrieval station. In this case, for the samples that need to be retrieved from the sample loading and unloading module 311, it is necessary to control the samples to be transferred from the sample loading and unloading module 311 to the retrieval station through the second sample scheduling and transmission module 500 and the main rail transmission system 200. Of course, when multiple sample analysis systems 300 are connected to the main rail transmission system 200, each sample analysis system 300 has different sample analysis and processing capabilities, or when a failure occurs in the corresponding sample analysis system 300, it is necessary to transfer the sample from the sample loading and unloading module 311 to other sample analysis systems 300 for analysis and processing. In this case, it is necessary to control the sample to be transferred from the sample loading and unloading module 311 to other sample analysis systems 300 through the second sample scheduling and transmission module 500 and the main rail transmission system 200.

[0124] The control analysis system transmission device 320 delivers samples to the first sample scheduling and transmission module 400, and controls the sample transfer module to transfer samples from the first sample scheduling and transmission module 400 to the sample loading and unloading module 311, and then from the sample loading and unloading module 311 to the second sample scheduling and transmission module 500, so that the second sample scheduling and transmission module 500 can deliver the samples to the main rail transmission system 200. Alternatively, the sample transfer module can be controlled to directly transfer samples from the first sample scheduling and transmission module 400 to the second sample scheduling and transmission module 500, so that the second sample scheduling and transmission module 500 can deliver the samples to the main rail transmission system 500. In this control method, samples can be transferred from the first sample scheduling and transmission module 400 to the main rail transmission system 200, and samples can be transferred through the main rail transmission system 200 to at least one of the pre-processing system 100, the retrieval station, and other sample analysis systems 300, which will not be elaborated further.

[0125] The main rail transmission system 200 delivers samples to the second sample scheduling transmission module 500, and the sample transfer module transfers samples from the second sample scheduling transmission module 500 to the sample loading / unloading module 311, and then from the sample loading / unloading module 311 to the first sample scheduling transmission module 400, so that the first sample scheduling transmission module 400 can deliver the samples to the analysis system transmission device 320. Alternatively, the sample transfer module can directly transfer samples from the second sample scheduling transmission module 500 to the first sample scheduling transmission module 400, so that the first sample scheduling transmission module 400 can deliver the samples to the analysis system transmission device 320. In this control method, samples in the main rail transmission system 200 can be transferred to the analysis system transmission device 320, thereby allowing the analysis system transmission device 320 to further transfer the samples to the corresponding sample analyzer 330 for analysis and processing.

[0126] Furthermore, as can be seen from the above examples, the TLA of this embodiment can perform at least one of the following steps to achieve the purpose of disaster recovery or disaster prevention:

[0127] The control sample transfer module transfers samples from the sample loading / unloading module 311 to the second sample scheduling and transmission module 500, and controls the second sample scheduling and transmission module 500 to deliver the samples to the main rail transmission system 200, and controls the main rail transmission system 200 to transmit the samples to the preprocessing system 100 or other sample analysis system 300 or sample recovery system. This control step can be used in at least one of the following scenarios:

[0128] If the pretreatment system 100 malfunctions, the sample analysis system 300 will replace the pretreatment system for sample loading and will transfer the sample to other sample analysis systems 300 or sample recovery systems via the main rail transfer system 200.

[0129] The preprocessing system 100 is working normally. The sample analysis system 300 loads the sample and transfers the sample that needs to be preprocessed by the preprocessing system 100 to the preprocessing system 100.

[0130] The pretreatment system 100 is working normally, the sample analysis system 300 loads the samples, and transfers samples that do not require pretreatment by the pretreatment system 100 to other sample analysis systems 300 or sample recovery systems.

[0131] When the analytical system transmission device 320 and / or the sample analyzer 330 malfunction, the analytical system sample loading device 310 is still connected to the main rail transmission system 200 and continues to work normally.

[0132] When a partial failure does not affect the transmission path consisting of the main rail transmission system 200 and the second sample scheduling transmission module 500, the system sample loading device 310 can still be connected to the main rail transmission system 200 and continue to work.

[0133] The control sample transfer module transfers samples from the sample loading / unloading module 311 to the first sample scheduling and transmission module 400, and controls the first sample scheduling and transmission module 400 to deliver the samples to the analysis system transmission device 320, and controls the analysis system transmission device 320 to transmit the samples to the corresponding sample analyzer 330. This control step can be used in at least one of the following scenarios:

[0134] All other parts of the TLA are normal. Currently, the sample analysis system 300 is being used alone for sample loading, sample scheduling, transmission, and analysis.

[0135] At least some of the other parts of the TLA fail (e.g., the pretreatment system 100 fails and / or the main rail transport system 200 fails), and the sample analysis system 300 is currently used alone for sample loading, sample scheduling, transport and analysis.

[0136] When a part of the sample transmission path not involving the first sample scheduling and transmission module 400 fails, the sample analysis system 300 is activated to perform sample loading, sample scheduling, transmission, and analysis; at this time, if other parts of the TLA are working normally, they may work normally or not.

[0137] The main track transmission system 200 delivers samples from the preprocessing system 100 or other sample analysis system 300 to the first sample scheduling and transmission module 400, controls the first sample scheduling and transmission module 400 to deliver the samples to the analysis system transmission device 320, and controls the analysis system transmission device 320 to transmit the samples to the corresponding sample analyzer 330. This control step can be used in at least one of the following scenarios:

[0138] Even if the sample loading / unloading module 311 and / or sample transfer module of the system sample loading device 310 malfunctions, the sample analysis capability of the sample analysis system 300 can still be maintained.

[0139] Even if the sample loading and unloading module 311 and / or sample transfer module of the system sample loading device 310 are normal but not activated, the sample analysis capability of the sample analysis system 300 can still be maintained.

[0140] The sample loading and unloading module 311 and / or sample transfer module of the system sample loading device 310 are normal and the sample loading and sample scheduling and transmission are normal. However, the samples scheduled for transmission are first transferred to the main rail transmission system, so the sample analysis capability of the sample analysis system 300 can still be maintained.

[0141] In one embodiment of this example, the TLA control method further includes at least one of the following control methods:

[0142] The main rail transport system 200 delivers samples from the pre-processing system 100 or other sample analysis systems 300 to the second sample scheduling and transport module 500, and controls the sample transfer module to transfer the sample from the second sample scheduling and transport module 500 to the sample loading and unloading module 311. The system sample loading device 310 can receive samples from the pre-processing system 100 or other sample analysis systems 300 for processing; for example, performing pre-processing, opening caps, or buffering, which can increase the sample throughput within the TLA.

[0143] The control and analysis system transmission device 320 delivers the sample processed by the sample analyzer 330 to the main rail transmission system 200 through the second sample scheduling transmission module 500 and the first sample scheduling transmission module 400. The main rail transmission system 200 then transmits the sample to the sample recovery position. In other words, the preferred control method is to recover all samples through the main rail transmission system 200, which facilitates centralized and scientific recovery management.

[0144] The control and analysis system transmission device 320 delivers the sample processed by the sample analyzer 330 to the first sample scheduling and transmission module 400, and controls the sample transfer module to transfer the sample from the first sample scheduling and transmission module 400 to the sample loading and unloading module 311. In this way, the tested sample can be recovered through the system sample loading device 310, thus realizing multi-point recovery.

[0145] It should be understood that at least one step of the control method described above in this embodiment can be controlled manually or by setting detection conditions for automatic control. These detection conditions can be set with reference to, but are not limited to, the application scenarios in the above examples, and will not be elaborated on here.

[0146] This embodiment also provides a computer program that can be executed by a processor or controller to implement the TLA control method shown above.

[0147] This embodiment also provides a computer storage medium that stores the computer program as described above, and the computer program can be invoked and executed by a processor or controller.

[0148] The above-described embodiments are merely preferred embodiments provided to fully illustrate the present invention, and the scope of protection of the present invention is not limited thereto. Equivalent substitutions or modifications made by those skilled in the art based on the present invention are all within the scope of protection of the present invention. The scope of protection of the present invention is defined by the claims.

Claims

1. An analytical system sample application device, characterized by: The sample loading device comprises a sample loading device body, a sample loading and unloading module, a sample transfer module, a first sample scheduling transmission module and a second sample scheduling transmission module are arranged on the sample loading device body; The sample loading and unloading module is configured to load or unload samples; The sample transfer module is configured to at least realize sample transfer between the sample loading and unloading module and the first sample scheduling transmission module, and between the sample loading and unloading module and the second sample scheduling transmission module; or, the sample transfer module is configured to at least realize sample transfer between the sample loading and unloading module and the first sample scheduling transmission module, between the sample loading and unloading module and the second sample scheduling transmission module, and between the first sample scheduling transmission module and the second sample scheduling transmission module; The first sample scheduling transmission module is configured to be connected with an analysis system transmission device to realize sample interaction between the first sample scheduling transmission module and the analysis system transmission device; the first sample scheduling transmission module is provided with a first sample transfer position for the sample transfer module to transfer samples; the analysis system transmission device is part of a sample analysis system and is configured to transmit samples to a corresponding sample analyzer in the sample analysis system; The second sample scheduling transmission module is configured to be connected with a main track transmission system to realize sample interaction between the second sample scheduling transmission module and the main track transmission system; the second sample scheduling transmission module is provided with a second sample transfer position for the sample transfer module to transfer samples; the main track transmission system is part of a full-laboratory automation pipeline and is configured to realize sample interaction between systems included in the full-laboratory automation pipeline.

2. The analytical system sample application apparatus of claim 1, wherein: The sample loading and unloading module comprises a sample loading carrier loaded with samples, the first sample scheduling transmission module and the second sample scheduling transmission module respectively adopt a first sample transmission carrier and a second sample transmission carrier to transmit samples; at least one of the first sample transmission carrier and the second sample transmission carrier is a single-tube transmission carrier capable of storing only one sample tube, or a multi-tube transmission carrier capable of simultaneously accommodating at least two sample tubes.

3. The analytical system sample application device of claim 2, wherein, The sample loading device body is provided with a centrifugation module, and the centrifugation module comprises a centrifuge and a centrifugation adapter; The sample transfer module is further configured to transfer the sample to the centrifugation adapter and transfer the centrifugation adapter from the centrifuge to the sample loading and unloading module.

4. The analytical system sample application apparatus of claim 2, wherein, At least two of the sample loading carrier, the first sample transmission carrier and the second sample transmission carrier are the same physical carrier or different physical carriers; And / or, the first sample transmission carrier and a third sample transmission carrier adopted by the analysis system transmission device are the same physical carrier or different physical carriers; And / or, the second sample transmission carrier and a fourth sample transmission carrier adopted by the main track transmission system are the same physical carrier or different physical carriers.

5. The analytical system sample application apparatus of claim 3, wherein, At least two of the sample loading carrier, the first sample transmission carrier and the centrifugation adapter are the same physical carrier or different physical carriers; Or, the first sample transport carrier and the centrifugal adapter are the same physical carrier, and the sample transfer module is further configured to transfer the centrifugal adapter from the centrifuge or from the sample loading and unloading module to the first sample scheduling and transport module.

6. An analytical system sample application device according to any one of claims 2 to 5, wherein: The first sample scheduling and transport module is provided with a first interface and a second interface; the first interface is used to receive the first sample transport carrier input from the analysis system transmission device; and the second interface is used to output the first sample transport carrier to the analysis system transmission device. And / or, The second sample scheduling and transport module is provided with a third interface and a fourth interface; the third interface is used to receive the second sample transport carrier input from the main track transport system; and the fourth interface is used to output the second sample transport carrier to the main track transport system.

7. The analytical system sample application apparatus of claim 6, wherein: When the first sample transport carrier is a single-tube transport carrier, the first interface and the second interface are independent of each other; the first sample scheduling and transport module includes a first sample scheduling track and a second sample scheduling track with opposite transmission directions; The first sample scheduling track is connected to the first interface; and the second sample scheduling track is connected to the second interface. When the first sample transport carrier is a multi-tube transport carrier, the first interface and the second interface overlap; and the first sample scheduling and transport module adopts a bidirectional transmission track with two opposite transmission directions. And / or, The second sample scheduling and transport module includes a third sample scheduling track and a fourth sample scheduling track with opposite transmission directions; the third sample scheduling track is connected to the third interface; and the fourth sample scheduling track is connected to the fourth interface.

8. The analytical system sample application device of any of claims 1-5 or 7, wherein: The sample loading device body is provided with a first accommodation area accommodating the first sample scheduling and transport module; one end of the first sample scheduling and transport module is fixed on the analysis system transmission device or the corresponding sample analyzer of the analysis system transmission device, and the other end extends into the first accommodation area; Or, the first sample scheduling and transport module is fixed on the sample loading device body; Or, the first sample scheduling and transport module includes a first sample scheduling sub-module and a second sample scheduling sub-module independent of each other; the sample loading device body is provided with a second accommodation area accommodating the second sample scheduling sub-module; the first sample scheduling sub-module is fixed on the sample loading device body; one end of the second sample scheduling sub-module is fixed on the analysis system transmission device or the corresponding sample analyzer of the analysis system transmission device, and the other end extends into the second accommodation area and is connected to the first sample scheduling sub-module; Or, the first sample scheduling and transport module is fixed on the sample loading device body, and the sample loading device body is further provided with a first height adjustment module adjusting the height of the first sample scheduling and transport module. Or, the first sample scheduling transmission module includes a first sample scheduling submodule and a second sample scheduling submodule, the upper sample device body is provided with a second accommodating area for accommodating the second sample scheduling submodule; the first sample scheduling submodule is fixedly arranged on the upper sample device body, and the upper sample device body is further provided with a second height adjusting module for adjusting the height of the first sample scheduling submodule; one end of the second sample scheduling submodule is fixed on the analysis system transmission device or a sample analyzer corresponding to the analysis system transmission device, and the other end of the second sample scheduling submodule extends into the second accommodating area and is connected with the first sample scheduling submodule.

9. The analytical system sample application device of any of claims 1-5 or 7, wherein: The upper sample device body is provided with a third accommodating area for accommodating the second sample scheduling transmission module, one end of the second sample scheduling transmission module is fixed on the main rail transmission system, and the other end of the second sample scheduling transmission module extends into the third accommodating area; Or, the second sample scheduling transmission module is fixedly arranged on the upper sample device body; Or, the second sample scheduling transmission module includes a third sample scheduling submodule and a fourth sample scheduling submodule, the upper sample device body is provided with a fourth accommodating area for accommodating the fourth sample scheduling transmission module, the third sample scheduling submodule is fixedly arranged on the upper sample device body, and one end of the fourth sample scheduling submodule is fixed on the main rail transmission system, and the other end of the fourth sample scheduling submodule extends into the fourth accommodating area and is connected with the third sample scheduling submodule; Or, the second sample scheduling transmission module is fixedly arranged on the upper sample device body, and the upper sample device body is further provided with a third height adjusting module for adjusting the height of the second sample scheduling transmission module; Or, the second sample scheduling transmission module includes a third sample scheduling submodule and a fourth sample scheduling submodule, the upper sample device body is provided with a fourth accommodating area for accommodating the fourth sample scheduling transmission module, the third sample scheduling submodule is fixedly arranged on the upper sample device body, and the upper sample device body is further provided with a fourth height adjusting module for adjusting the height of the third sample scheduling submodule; one end of the fourth sample scheduling submodule is fixed on the main rail transmission system, and the other end of the fourth sample scheduling submodule extends into the fourth accommodating area and is connected with the third sample scheduling submodule.

10. The analytical system sample application device of any of claims 1-5 or 7, wherein: The first sample scheduling transmission module and the second sample scheduling transmission module are arranged on different sides of the upper sample device body; And / or, The analysis system sample loading device includes one first sample scheduling transmission module and one second sample scheduling transmission module, or the analysis system sample loading device includes one second sample scheduling transmission module and at least two first sample scheduling transmission modules, and different first sample scheduling transmission modules are connected with different analysis system transmission devices.

11. The analytical system sample application device of any of claims 1-5 or 7, wherein: The sample transfer module is a three-dimensional mechanical hand arranged on the sample device body, and / or the analysis system sample loading device further includes at least one of a code reading module, a panoramic vision module, a light source module, a first cover opening module and a drawer module; The code reading module is arranged on the sample transfer module and moves with the sample transfer module, and the code reading module is configured to read at least one of the barcode information and the sample characteristic information of the sample when the sample transfer module transfers the sample, and the sample characteristic information includes at least one of the sample amount, the sample tube shape, the sample tube cap color, the sample tube cap shape, the sample tube size, and the sample color. The panoramic vision module is configured to obtain a panoramic image of the sample loading and unloading module. The light source module is configured to irradiate a shooting area of at least one of the code reading module and the panoramic vision module. The first cap opening module is configured to perform a cap opening action on the cap of the sample. The sample loading and unloading module is composed of at least one drawer module, wherein the drawer module includes at least one of a manual drawer and an electric drawer, and / or the drawer module is perpendicular to the transmission direction of the analysis system transmission device, and / or the sample loading and unloading module includes at least one of a sample buffer area, an emergency sample loading and unloading module, a recheck sample loading and unloading module, and an abnormal sample loading and unloading module.

12. A sample analysis system, characterized by, The system analysis device and the sample loading and unloading device of any one of claims 1-11 are included. The system analysis device includes a sample analyzer and an analysis system transmission device adapted to the sample analyzer. The first sample scheduling transmission module is configured to interface with the analysis system transmission device to realize sample interaction between the first sample scheduling transmission module and the analysis system transmission device. The analysis system transmission device is configured to transmit the sample from the first sample scheduling transmission module to the sample analyzer. The sample analyzer is configured to analyze and process the sample.

13. The sample analysis system of claim 12, wherein, The sample analysis system includes two system analysis devices. The sample loading and unloading device includes one second sample scheduling transmission module and two first sample scheduling transmission modules, and the two first sample scheduling transmission modules interface with the analysis system transmission devices of the two system analysis devices, respectively. And / or, the two first sample scheduling transmission modules are arranged on opposite sides of the sample loading and unloading device body.

14. A full-lab automation pipeline, characterized in that, The pre-processing system, the main rail transmission system, and at least one sample analysis system arranged along the main rail transmission system are included, and at least one of the sample analysis systems is the sample analysis system of claim 12 or 13. The pre-processing system interfaces with the main rail transmission system to enable sample interaction. The sample loading and unloading device is arranged between the main rail transmission system and the analysis system transmission device, the first sample scheduling transmission module interfaces with the analysis system transmission device, and the second sample scheduling transmission module interfaces with the main rail transmission system.

15. A method of controlling a total laboratory automation line as claimed in claim 14, characterized in that, At least one of the following control steps is included: The sample transfer module is controlled to transfer the sample from the sample loading and unloading module to the first sample scheduling transmission module, and the first sample scheduling transmission module is controlled to deliver the sample to the analysis system transmission device, so that the analysis system transmission device transmits the sample to the corresponding sample analyzer. controlling the sample transfer module to transfer the sample from the sample loading and unloading module to the second sample dispatching and transport module for the second sample dispatching and transport module to deliver the sample to the main track transport system, and controlling the main track transport system to transport the sample to at least one of the pre-processing system, a recycling location, and other sample analysis systems; controlling the sample transfer module to transfer the sample from the sample loading and unloading module to the second sample dispatching and transport module for the second sample dispatching and transport module to deliver the sample to the main track transport system, and controlling the main track transport system to transport the sample to at least one of the pre-processing system, a recycling location, and other sample analysis systems; controlling the sample transfer module to transfer the sample from the sample loading and unloading module to the second sample dispatching and transport module for the second sample dispatching and transport module to deliver the sample to the main track transport system, and controlling the main track transport system to transport the sample to at least one of the pre-processing system, a recycling location, and other sample analysis systems;

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