Multifunctional pipetting platform

Abstract

The invention discloses a multifunctional pipetting platform, and relates to the technical field of chemical equipment. Comprising a bottom plate, a longitudinal linear guide rail sliding table is arranged on the top of the bottom plate in parallel through a square column, a transverse linear guide rail sliding table is movably arranged on the longitudinal linear guide rail sliding table, a transverse sliding block is arranged on the transverse linear guide rail sliding table, and a pipetting table is arranged on the transverse sliding block; a liquid collecting pool is arranged on the top surface of the bottom plate and located on the inner side of the square column, a clamping mechanism is arranged on the surface of the bottom plate, a bottle rack is arranged on the surface of the bottom plate, and reagent bottles are arranged on the bottle rack. Through an orthogonal driving structure of the longitudinal linear guide rail sliding table and the transverse linear guide rail sliding table and in cooperation with transmission of the servo motor and the ball screw, multi-dimensional precise displacement of the pipetting table and the pipetting gun is achieved, the repeated positioning precision and the pipetting precision are high, and personal errors are reduced.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of chemical equipment, in particular to a multifunctional pipetting platform. BACKGROUND

[0002] In the daily operation of biological, chemical and other laboratories, pipetting is one of the core basic operations, which needs to be accurately completed for reagent suction, transfer and release. The existing pipetting equipment has the problems of single function and poor adaptability: the traditional manual pipetting gun relies on manual operation, the precision is easily affected by human factors, and batch processing cannot be realized; ordinary electric pipetting platforms can only realize single-dimensional pipetting action, lack flexible clamping fixing mechanism, and are difficult to adapt to different specifications of reagent bottles, test tubes and other containers; at the same time, in the special experimental environment of corrosion, high and low temperature, the material and structure of conventional equipment are easily damaged, which leads to short service life and cannot guarantee the safety of experiment and the purity of sample. In addition, the operation process of the existing equipment lacks coherence, and the functions of pipetting, stirring and batch processing cannot be realized simultaneously, which is low in efficiency. SUMMARY

[0003] In order to achieve the above purpose, the present application provides the following technical scheme: a multifunctional pipetting platform, comprising a bottom plate, a longitudinal linear guide rail sliding table is arranged in parallel on the top of the bottom plate through a square column, a transverse linear guide rail sliding table is movably arranged on the longitudinal linear guide rail sliding table, a transverse sliding block is arranged on the transverse linear guide rail sliding table, a pipetting table is arranged on the transverse sliding block, a liquid collecting pool is arranged on the top surface of the bottom plate and inside the square column, a clamping mechanism is arranged on the surface of the bottom plate, a bottle rack is arranged on the surface of the bottom plate, and a reagent bottle is arranged on the bottle rack, wherein the pipetting table is located above the liquid collecting pool, the bottle rack and the reagent bottle, a control console is arranged on the surface of the bottom plate and close to the side edge, and the control console is electrically connected with the longitudinal linear guide rail sliding table, the transverse linear guide rail sliding table and the pipetting table.

[0004] As a preferred technical scheme of the present application, an electromagnetic stirring table is arranged on the top of the bottom plate, the electromagnetic stirring table is connected with a power supply, the reagent bottle and the beaker can be placed on the electromagnetic stirring table, and stirring is realized by putting magnetic stirring particles into the reagent bottle and the beaker.

[0005] As a preferred technical scheme of the present application, the clamping mechanism is arranged on the surface of the bottom plate, wherein an active hole is arranged on the top surface of the clamping mechanism, a motor is arranged in the clamping mechanism, a driving double-toothed screw rod is arranged at the output end of the motor, two groups of transverse sliding blocks are sleeved on the driving double-toothed screw rod, a clamping rod is arranged on one group of transverse sliding blocks, a test tube clamp is arranged on the other group of transverse sliding blocks, and the test tube clamp and the clamping rod are arranged through the active hole.

[0006] As a preferred technical scheme of the present application, one side of the clamping rod is provided with an arc-shaped groove, and the placing part of the test tube clamp is arranged in the shape of "[", wherein the top of the "[ " is provided with a circular hole.

[0007] As a preferred technical scheme of the present application, the transverse slider sleeved outside the driving double-toothed screw rod is connected with the clamping rod and the test tube clamp through bolts, wherein the screw threads in the middle of the transverse slider are opposite in direction.

[0008] As a preferred technical scheme of the present application, the pipetting platform is movable on the transverse linear guide rail sliding table through the transverse slider, a back plate is arranged on the transverse slider, the pipetting platform is fixedly connected with the back plate, two groups of servo motors are arranged on the top of the back plate, long lead screws and lifting lead screws are arranged at the output ends of the two groups of servo motors.

[0009] As a preferred technical scheme of the present application, a lifting slider is movably arranged on the lifting lead screw, and a servo rotary electric claw is arranged on the outer side of the lifting slider.

[0010] As a preferred technical scheme of the present application, a vertical slider is sleeved outside the long lead screw, a pipetting gun is arranged on the outer side of the vertical slider, and a gun head is arranged at the output end of the pipetting gun.

[0011] As a preferred technical scheme of the present application, two groups of tank chains are arranged on the outer side of the back plate, and the tank chains are fixedly connected with the lifting slider and the vertical slider respectively.

[0012] As a preferred technical scheme of the present application, the placing part of the test tube clamp is arranged in the shape of "[", and the reagent test tube is inserted into the test tube clamp through the circular hole arranged on the top.

[0013] Advantages

[0014] Compared with the prior art, the present application provides a multifunctional pipetting platform, which has the following advantages: 1. The multifunctional pipetting platform realizes multi-dimensional accurate displacement of the pipetting platform and the pipetting gun through the orthogonal driving structure of the longitudinal and transverse linear guide rail sliding tables, the cooperation of the servo motors and the ball screw transmission, high repeat positioning accuracy and pipetting accuracy, and reduction of human error.

[0015] 2. The multifunctional pipetting platform adopts an adjustable and replaceable design for the clamping mechanism, which is suitable for containers of different specifications and shapes, and the pipetting gun supports capacity adjustment and multi-head design to meet the needs of routine and batch processing, integrates pipetting, clamping and stirring functions, the servo rotary electric claw can assist in completing container fixing and angle adjustment, the control console supports program presetting and automatic operation, and the operation continuity and efficiency are improved. BRIEF DESCRIPTION OF DRAWINGS

[0016] Figure 1 A schematic diagram of a multifunctional pipetting platform of the present application Figure 2 A schematic diagram of part of the structure in the present application Figure One ; Figure 3 A schematic diagram of part of the structure in the present application Figure Two ; Figure 4 A schematic diagram of part of the structure in the present application Figure Three ; Figure 5 A schematic diagram of part of the structure in the present application Figure Four ; Figure 6 A schematic diagram of part of the structure in the present application Figure Five .

[0017] In the figure: 1, base plate; 2, longitudinal linear guide rail sliding table; 3, transverse linear guide rail sliding table; 4, control console; 5, liquid collection tank; 6, bottle rack; 7, reagent bottle; 8, clamping mechanism; 9, electromagnetic stirring table; 10, pipetting table; 11, clamping rod; 12, test tube clamping rack; 13, liquid preparation test tube; 14, motor; 15, driving double-toothed screw; 16, transverse sliding block; 17, back plate; 18, servo motor; 19, servo rotary electric claw; 20, pipetting gun; 21, long screw; 22, vertical sliding block; 23, gun head; 24, tank chain; 25, lifting screw; 26, lifting sliding block. DETAILED DESCRIPTION

[0018] The technical solutions in the embodiments of the present application will be described clearly and completely below with reference to the accompanying drawings in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, rather than all the embodiments. Based on the embodiments in the present application, all other embodiments obtained by those of ordinary skill in the art without creative work fall within the protection scope of the present application.

[0019] Embodiment one: Please refer to Figures 1-6The application discloses a multifunctional pipetting platform, which comprises a bottom plate 1, a longitudinal linear guide rail sliding table 2 is arranged on the top of the bottom plate 1 in parallel through a square column, a transverse linear guide rail sliding table 3 is movably arranged on the longitudinal linear guide rail sliding table 2, a transverse sliding block is arranged on the transverse linear guide rail sliding table 3, a pipetting table 10 is arranged on the transverse sliding block, a liquid collecting pool 5 is arranged on the top surface of the bottom plate 1 and located on the inner side of the square column, a clamping mechanism 8 is arranged on the surface of the bottom plate 1, a bottle rack 6 is arranged on the surface of the bottom plate 1, a reagent bottle 7 is arranged on the bottle rack 6, wherein the pipetting table 10 is located above the liquid collecting pool 5, the bottle rack 6 and the reagent bottle 7, a control console 4 is arranged on the surface of the bottom plate 1 and close to the side edge, and the control console 4 is electrically connected with the longitudinal linear guide rail sliding table 2, the transverse linear guide rail sliding table 3 and the pipetting table 10.

[0020] The longitudinal linear guide rail sliding table 2 and the transverse linear guide rail sliding table 3 are arranged, so that pipetting and liquid taking can be realized at multiple positions, wherein the longitudinal linear guide rail sliding table 2 and the transverse linear guide rail sliding table 3 both adopt a ball screw transmission structure and are matched with high-precision grating ruler positioning, the repeated positioning accuracy reaches ±0.01 mm, the pipetting table 10 can cover target positions of the liquid collecting pool 5, the bottle rack 6 and the clamping mechanism 8 in the whole horizontal direction, and the accurate pipetting requirement of experiments is met. The control console 4 is internally provided with a PLC control system, supports two modes of manual key operation and preset program operation, and operation personnel can directly input and operate pipetting positions, pipetting volumes and other parameters through an external control panel of the control console 4, so that the operation is convenient.

[0021] Specifically, an electromagnetic stirring table 9 is arranged on the top of the bottom plate 1, the electromagnetic stirring table 9 is externally connected with a power supply, the reagent bottle 7 and a beaker can be placed on the electromagnetic stirring table 9, and stirring can be realized by throwing magnetic stirring particles into the reagent bottle 7 and the beaker.

[0022] In the embodiment, the reagent bottle 7 or the beaker is placed on the electromagnetic stirring table 9, and stirring of liquid is realized by throwing magnetic stirring particles into the reagent bottle 7 and the beaker, so that subsequent pipetting operation is facilitated, and it should be noted that the reagent bottle 7 or the beaker placed on the electromagnetic stirring table 9 can be operated by an external mechanical hand or manually.

[0023] Specifically, the clamping mechanism 8 is arranged on the surface of the bottom plate 1, wherein a movable hole is arranged on the top surface of the clamping mechanism 8, a motor 14 is arranged in the clamping mechanism 8, a driving double-threaded screw rod 15 is arranged at the output end of the motor 14, two groups of transverse sliding blocks 16 are sleeved on the driving double-threaded screw rod 15, a clamping rod 11 is arranged on one group of the transverse sliding blocks 16, and a test tube clamping frame 12 is arranged on the other group of the transverse sliding blocks 16, wherein the test tube clamping frame 12 and the clamping rod 11 pass through the movable hole and are arranged, the transverse sliding blocks 16 sleeved on the outer side of the driving double-threaded screw rod 15 are connected with the clamping rod 11 and the test tube clamping frame 12 through bolts, and the thread directions of the middle portions of the transverse sliding blocks 16 are opposite. The placement part of the test tube holder 12 is arranged in a "[", and the liquid preparation test tube 13 is inserted into the test tube holder 12 through the circular hole provided at the top.

[0024] An arc-shaped groove is provided on one side of the clamping rod 11, and the placement part of the test tube holder 12 is arranged in a "[", wherein a circular hole is provided at the top of the "[", and the clamping rod 11 is used in cooperation with the test tube holder 12 of the "[".

[0025] In this embodiment, the motor 14 of the clamping mechanism 8 is a stepper motor, which has stable torque output. The motor 14 can be driven by the control console 4 to adjust and clamp the test tube. The connecting bolts of the horizontal sliding block 16, the clamping rod 11 and the test tube holder 12 are hexagonal head bolts, which are stable in connection and convenient to disassemble. Only a special wrench is needed to quickly replace the clamping parts, which are suitable for special-shaped containers. The driving double-threaded rod 15 ensures that the horizontal sliding block 16 moves at a uniform speed, and the clamping action is stable and has no impact, thereby realizing the stable clamping of the test tube holder 12 and the clamping rod 11 on the reagent bottle 7 and the small test tube. A wear-resistant nylon bushing is arranged on the inner wall of the movable hole to reduce the friction loss when the clamping rod 11 and the test tube holder 12 move, thereby prolonging the service life of the device. A non-slip rubber pad is pasted on the inner wall of the arc-shaped groove of the clamping rod 11, and a non-slip pattern is provided on the surface to increase the friction force with the outer wall of the container, thereby avoiding clamping slip. The inside of the "["] shaped placement part of the test tube holder 12 is provided with a flexible buffer layer, and the top circular hole can adapt to three standard sizes of 12mm, 15mm and 18mm, which are compatible with commonly used test tube models in laboratories, without the need for additional replacement of the holder. The liquid preparation test tube 13 and the test tube holder 12 are designed by interference fit, which not only ensures stable placement, but also facilitates quick taking and placing.

[0026] Specifically, the pipetting table 10 is movable on the horizontal linear guide rail sliding table 3 through the horizontal sliding block, and the horizontal sliding block is provided with a back plate 17. The pipetting table 10 is fixedly connected with the back plate 17. Two groups of servo motors 18 are installed on the top of the frame of the back plate 17. Long lead screws 21 and lifting lead screws 25 are respectively arranged at the output ends of the two groups of servo motors 18. The lifting sliding block 26 is movably arranged on the lifting lead screw 25, and the outer side of the lifting sliding block 26 is provided with a servo rotary electric claw 19.

[0027] In this embodiment, the back plate 17 of the pipetting table 10 is made of aluminum alloy, which is light in weight and corrosion-resistant. The two groups of servo motors 18 accurately control the rotation angles of the long lead screw 21 and the lifting lead screw 25 through pulse signals, realize the accurate displacement of the pipetting gun 20 and the servo rotary electric claw 19, and ensure the coherence of the pipetting process. The clamping stroke of the servo rotary electric claw 19 is 0-20mm, and the rotation angle range is 0-360°. The servo rotary electric claw 19 can rotate and clamp 360° without dead angle, can fix the reagent bottle 7 before pipetting, and can adjust the angle of the liquid preparation test tube 13 after pipetting. The claw fingers of the servo rotary electric claw 19 are provided with anti-skid teeth, and the reagent bottle 7 can also be rotated and opened and closed. The claw fingers are made of stainless steel and are passivated on the surface, which is corrosion-resistant and not easy to contaminate the reagent.

[0028] Specifically, the long lead screw 21 is sleeved with a vertical sliding block 22, and the outer side of the vertical sliding block 22 is provided with a pipette 20. The output end of the pipette 20 is provided with a gun head 23.

[0029] In the embodiment, the pipette 20 is selected to be adjustable in volume, and the volume adjustment range is 10-1000μL. The gun head 23 is a disposable sterile gun head, which is buckled and connected for easy replacement to avoid cross contamination. The gap between the vertical sliding block 22 and the long lead screw 21 is less than 0.02mm, which ensures that the vertical lifting of the pipette 20 does not shake, and the gun head 23 accurately extends into the specified depth of the container.

[0030] Specifically, the outer side of the frame installed on the back plate 17 is provided with two groups of tank chains 24, which are respectively fixedly connected with the lifting sliding block 26 and the vertical sliding block 22.

[0031] In the embodiment, the tank chain 24 is made of bridge-enhanced nylon material, which internally stores power lines and signal lines, and is arranged in order to avoid entanglement. The bending radius is 50mm, which is suitable for the maximum moving stroke of the sliding block to ensure that the wire harness is not pulled or worn to ensure stable electrical connection.

[0032] Example two: The difference between the embodiment and the above embodiment is that: in the embodiment, the arc-shaped groove of the clamping rod 11 adopts a replaceable structure, which is fixed on the clamping rod body by bolts, and can replace the arc-shaped, V-shaped, and planar clamping surfaces to adapt to square and special-shaped containers. The top circular hole of the test tube clamp 12 adopts a hole diameter adjustable design. By rotating the side knob, the hole diameter is continuously adjustable within a range, and a variety of specifications of liquid preparation test tubes 13 can be adapted without replacing the clamp.

[0033] The servo rotary electric claw 19 is equipped with a torque sensor, which transmits data to the control console 4, and the clamping force is fed back in real time through the external control panel. The clamping force is detected in real time, and the clamping is automatically stopped when the preset threshold is reached to avoid damaging the container or squeezing the reagent. The electric claw head supports quick replacement of two-claw and three-claw heads. The two-claw head is suitable for regular circular containers, and the three-claw head is suitable for irregularly shaped containers, which increases the adaptability of the servo rotary electric claw 19.

[0034] The pipette 20 adopts a multi-head design, a single set of pipette integrates three independent heads 23, can simultaneously pipette three target containers, batch processing efficiency is improved, the pipette is built-in high-precision pressure sensor, real-time monitoring of liquid suction and liquid pressure, when the liquid suction is insufficient, the liquid residue and other abnormalities, through the control console 4 sound and light alarm, timely remind the operator. The rest of the structure is the same as example one.

[0035] It should be noted that in this text, such as the term "includes", "contains" or any other variant is intended to cover non-exclusive inclusion, so that the process, method, article or equipment including a series of elements not only includes those elements, but also includes other elements not explicitly listed, or also includes the elements inherent in such process, method, article or equipment. Without more limitations, the element defined by the statement "includes a" does not exclude the presence of other identical elements in the process, method, article or equipment including the element.

[0036] Although embodiments of the present application have been shown and described, it will be understood by those having ordinary skill in the art that various changes, modifications, alternatives and variations can be made thereto without departing from the principles and spirit of the application, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A multifunctional pipetting platform comprising a base plate (1), characterized in that, The top of the bottom plate (1) is provided with a longitudinal linear guide rail sliding table (2) through a square column, the longitudinal linear guide rail sliding table (2) is movably provided with a transverse linear guide rail sliding table (3), the transverse linear guide rail sliding table (3) is provided with a transverse sliding block, the transverse sliding block is provided with a pipetting table (10), the top surface of the bottom plate (1) and located inside the square column is provided with a liquid collecting pool (5), the surface of the bottom plate (1) is provided with a clamping mechanism (8), the surface of the bottom plate (1) is provided with a bottle rack (6), the bottle rack (6) is provided with a reagent bottle (7), wherein the pipetting table (10) is located above the liquid collecting pool (5), the bottle rack (6) and the reagent bottle (7), the surface of the bottom plate (1) and close to the side edge is provided with a control console (4), the control console (4) is electrically connected with the longitudinal linear guide rail sliding table (2), the transverse linear guide rail sliding table (3) and the pipetting table (10).

2. The multi-functional pipetting platform of claim 1, wherein: The top of the bottom plate (1) is provided with an electromagnetic stirring table (9), the electromagnetic stirring table (9) is connected with a power supply, the reagent bottle and the beaker can be placed on the electromagnetic stirring table (9), and stirring is realized by putting magnetic stirring particles into the reagent bottle and the beaker.

3. The multi-functional pipetting platform of claim 1, wherein: The clamping mechanism (8) is arranged on the surface of the bottom plate (1), wherein the top surface of the clamping mechanism (8) is provided with a movable hole, the inside of the clamping mechanism (8) is provided with a motor (14), the output end of the motor (14) is provided with a driving double-toothed screw rod (15), two groups of transverse sliding blocks (16) are sleeved on the driving double-toothed screw rod (15), a group of transverse sliding blocks (16) are provided with a clamping rod (11), and the other group of transverse sliding blocks (16) are provided with a test tube clamping frame (12), wherein the test tube clamping frame (12) and the clamping rod (11) are arranged through the movable hole.

4. The multi-functional pipetting platform of claim 3, wherein: An arc-shaped groove is formed in one side of the clamping rod (11), and the placing part of the test tube clamping frame (12) is arranged in the shape of "[", wherein a circular hole is formed through the top of the "[", and the clamping rod (11) is used in cooperation with the test tube clamping frame (12) of the "[".

5. The multi-functional pipetting platform of claim 3, wherein: The transverse sliding blocks (16) sleeved on the outside of the driving double-toothed screw rod (15) are connected with the clamping rod (11) and the test tube clamping frame (12) through bolts, wherein the thread directions of the middle parts of the transverse sliding blocks (16) are opposite.

6. The multi-functional pipetting platform of claim 1, wherein: The pipetting table (10) is movably arranged on the transverse linear guide rail sliding table (3) through the transverse sliding block to realize multi-position pipetting, a back plate (17) is arranged on the transverse sliding block, the pipetting table (10) is fixedly connected with the back plate (17), two groups of servo motors (18) are arranged on the top of the mounting frame of the back plate (17), and long lead screws (21) and lifting lead screws (25) are respectively arranged at the output ends of the two groups of servo motors (18).

7. The multi-functional pipetting platform of claim 6, wherein: A lifting sliding block (26) is movably arranged on the lifting lead screw (25), and a servo rotary electric claw (19) is arranged on the outside of the lifting sliding block (26).

8. The multi-functional pipetting platform of claim 6, wherein: A vertical sliding block (22) is sleeved on the outside of the long lead screw (21), a pipetting gun (20) is arranged on the outside of the vertical sliding block (22), and a gun head (23) is arranged at the output end of the pipetting gun (20).

9. The multi-functional pipetting platform of claim 1, wherein: The outer side of the frame installed on the back plate (17) is provided with two groups of tank chains (24), and the tank chains (24) are fixedly connected with lifting sliders (26) and vertical sliders (22) respectively.

10. The multi-functional pipetting platform of claim 4, wherein: The placing part of the test tube holder (12) is provided with a "[", and the liquid preparation test tube (13) is inserted with the test tube holder (12) through the circular hole opened on the top.

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