Biological protein purification equipment based on AI intelligence
By introducing an AI intelligent control system into the biological protein purification equipment, the problem of the equipment's inability to be remotely and automatically controlled has been solved, achieving a highly efficient protein purification process.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- SUZHOU JIUTONG HENGTAI MEDICAL TECHNOLOGY CO LTD
- Filing Date
- 2023-11-30
- Publication Date
- 2026-04-17
AI Technical Summary
Existing biological protein purification equipment lacks intelligent control mechanisms, making remote automatic control impossible and affecting its effectiveness.
The system employs an AI-powered intelligent control system, including a controller, memory, communication module, temperature sensor, and heating plate, to achieve remote monitoring and automatic control. Combined with motor-driven centrifugation and stirring functions, it improves purification efficiency.
It enables remote automatic control and efficient purification of biological protein purification equipment, thereby improving the equipment's performance.
Smart Images

Figure CN121868968A_ABST
Abstract
Description
Technical Field
[0001] This invention relates to the field of protein purification equipment technology, and in particular to an AI-based intelligent biological protein purification device. Background Technology
[0002] Artificial intelligence (AI) is an interdisciplinary and emerging field based on computer science, integrating computer science, psychology, philosophy, and other disciplines. It studies and develops theories, methods, technologies, and application systems to simulate, extend, and expand human intelligence. It attempts to understand the essence of intelligence and produce a new kind of intelligent machine that can react in a way similar to human intelligence. Research in this field includes robotics, speech recognition, image recognition, natural language processing, and expert systems.
[0003] Protein isolation and purification is a core technology in the modern biotechnology industry. This technology is both challenging and costly; 75% of the cost of a biopharmaceutical is spent on downstream protein isolation and purification, making it crucial to improve protein purification efficiency. However, current protein isolation and purification methods generally include cell disruption, crude protein analysis, and isolation and purification; each step involves multiple methods, among which cell disruption is the most basic and convenient step for large-scale protein preparation.
[0004] Mechanical disruption, dialysis disruption, and repeated freeze-thaw cycles all require significant time during cell disruption. Ultrasonic methods and differential centrifugation greatly improve cell disruption efficiency and time, with differential centrifugation being particularly simple and efficient. Providing ultra-high-speed centrifugation can further accelerate the disruption process.
[0005] However, the existing biological protein purification equipment has a relatively simple structure and lacks a certain intelligent control mechanism, making it impossible to remotely and automatically control the equipment, thus affecting its effectiveness. Summary of the Invention
[0006] 1. Technical problems to be solved
[0007] The purpose of this invention is to solve the problem that existing purification equipment lacks a certain intelligent control mechanism and cannot be remotely and automatically controlled, and to propose an AI-based intelligent biological protein purification device.
[0008] 2. Technical Solution
[0009] To achieve the above objectives, the present invention adopts the following technical solution:
[0010] A bioprotein purification device based on AI includes a base, a control box, and a main body. The control box is fixedly connected to the top of the base. A touch screen is fixedly connected to the outer wall of the control box. The control box contains a controller, a memory, a communication module, and a power supply. A first motor is fixedly connected to the top of the base. The output end of the first motor is fixedly connected to the bottom of the main body. A support mechanism is fixedly connected to the bottom of the main body.
[0011] The top of the main housing is provided with a feed inlet, and a cover plate is slidably inserted into the feed inlet. One end of the cover plate passes through the inner wall of the feed inlet and extends outward. The outer wall of the main housing is provided with a locking mechanism corresponding to the cover plate. A discharge pipe is fixedly inserted into the bottom of the inner wall of one side of the main housing, and a discharge valve is threaded onto the discharge pipe. Multiple temperature sensors and heating plates are fixedly connected to the inner wall of the main housing.
[0012] A filter frame is slidably inserted into the main box. Multiple positioning blocks are fixedly connected to the bottom of the main box. The bottom of the filter frame is provided with a positioning groove corresponding to the positioning block. A clamping mechanism is fixedly connected to the top of the filter frame. A slot corresponding to the clamping mechanism is provided on the inner wall of the main box. A support rod is fixedly connected to the top of the filter frame. A second motor is fixedly connected to the support rod. A rotating rod is fixedly connected to the output end of the second motor. A spiral stirring belt is wrapped around the rotating rod.
[0013] The output terminals of the temperature sensor and the power supply are both connected to the input terminal of the controller. The output terminal of the controller is connected to the input terminals of the memory, the first motor, the second motor, and the heating plate, respectively. The output terminals of the communication module and the touch screen are both connected to the input terminal of the controller.
[0014] Preferably, the bottom of the base is rotatably connected to multiple universal self-locking wheels.
[0015] Preferably, a power connector is fixedly embedded on the outer wall of the control box, and the output end of the power connector is connected to the input end of the power supply.
[0016] Preferably, the support mechanism includes a plurality of symmetrically arranged slide rods, the bottom of which is fixedly connected to a slider, and the top of the base is provided with an annular slide rail corresponding to the slider.
[0017] Preferably, a plurality of steel balls are slidably connected inside the annular slide rail, and the edges of the steel balls are in contact with the slider.
[0018] Preferably, the cover plate is provided with an observation port, and a transparent glass plate is fixedly inserted into the observation port.
[0019] Preferably, the locking mechanism includes a fixed rod, an L-shaped locking rod slidably sleeved on the fixed rod, and a first spring sleeved on the fixed rod, with the two ends of the first spring fixedly connected to the L-shaped locking rod and the inner wall of the locking groove, respectively.
[0020] Preferably, the clamping mechanism includes a clamping block, on which a clamping rod is slidably inserted. A clamping sleeve is fixedly sleeved at one end of the clamping rod near the main housing, and a pull rod is fixedly connected at the other end of the clamping rod away from the clamping sleeve.
[0021] Preferably, a second spring is sleeved on the lever, and the two ends of the second spring are fixedly connected to the sleeve and the block, respectively.
[0022] 3. Beneficial effects
[0023] Compared with the prior art, the advantages of this invention are:
[0024] (1) In this invention, by setting up a monitoring and control mechanism, the purification equipment can be remotely and automatically controlled, thereby effectively improving the performance of the biological protein purification equipment.
[0025] (2) In this invention, the temperature inside the main chamber can be monitored by setting a temperature sensor, and then the monitoring signal is sent to the controller. The controller controls the electric heating plate to start according to the preset threshold to heat the material inside the main chamber. The communication module can receive or send remote control commands, and the touch screen can display data and input control commands.
[0026] (3) In this invention, the material can be introduced into the filter frame through the feed port, and then the first motor is started to drive the main box to rotate, and the biological protein is centrifuged and purified. At the same time, the second motor is started to drive the rotating rod to rotate, thereby driving the spiral stirring belt to stir the material and improve the purification efficiency. Meanwhile, the setting of the clamping mechanism can facilitate the fixing and disassembly of the filter frame, and the locking mechanism can facilitate the fixing of the cover plate. Attached Figure Description
[0027] Figure 1 This is a schematic diagram of the structure of an AI-based intelligent biological protein purification device proposed in this invention;
[0028] Figure 2 This is a top view of the filter frame of an AI-based bioprotein purification device proposed in this invention.
[0029] Figure 3 for Figure 1 A schematic diagram of the structure at point A;
[0030] Figure 4 This is a schematic diagram of the control system for an AI-based intelligent biological protein purification device proposed in this invention.
[0031] In the diagram: 1. Base, 2. Control box, 3. Main body, 4. Touch screen, 5. Controller, 6. Memory, 7. Communication module, 8. Power supply, 9. First motor, 10. Cover plate, 11. Discharge pipe, 12. Discharge valve, 13. Temperature sensor, 14. Heating plate, 15. Filter frame, 16. Positioning block, 17. Support rod, 18. Second motor, 19. Rotating rod, 20. Spiral stirring belt, 21. Universal self-locking wheel, 22. Power connector, 23. Slide rod, 24. Slider, 25. Steel ball, 26. Transparent glass plate, 27. Fixing rod, 28. L-shaped locking rod, 29. First spring, 30. Locking block, 31. Locking rod, 32. Locking sleeve, 33. Pull rod, 34. Second spring. Detailed Implementation
[0032] The technical solutions of the present invention will be clearly and completely described below with reference to the accompanying drawings of the embodiments of the present invention. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments.
[0033] Example 1:
[0034] Reference Figure 1-4 A bioprotein purification device based on AI intelligence includes a base 1, a control box 2, and a main body 3. The bottom of the base 1 is rotatably connected with multiple universal self-locking wheels 21 for easy movement of the base 1. The control box 2 is fixedly connected to the top of the base 1. A touch screen 4 is fixedly connected to the outer wall of the control box 2 for easy input of commands and display of monitoring data. The control box 2 is equipped with a controller 5, a memory 6, a communication module 7, and a power supply 8. A first motor 9 is fixedly connected to the top of the base 1 for driving the main body 3 to rotate. The output end of the first motor 9 is fixedly connected to the bottom of the main body 3.
[0035] In this invention, a support mechanism is fixedly connected to the bottom of the main box 3 to support the main box 3. The support mechanism includes a plurality of symmetrically arranged sliding rods 23. A slider 24 is fixedly connected to the bottom of the sliding rod 23. An annular slide rail corresponding to the slider 24 is provided on the top of the base 1. A plurality of steel balls 25 are slidably connected inside the annular slide rail. The edges of the steel balls 25 are in contact with the slider 24 to reduce the friction between the slider 24 and the inner wall of the annular slide rail.
[0036] In this invention, the top of the main box 3 is provided with a feed inlet for easy material introduction. A cover plate 10 is slidably inserted into the feed inlet to prevent material leakage. One end of the cover plate 10 penetrates the inner wall of the feed inlet and extends outward. The outer wall of the main box 3 is provided with a locking mechanism corresponding to the cover plate 10 for easy fixing of the cover plate 10. The locking mechanism includes a fixing rod 27, an L-shaped locking rod 28 is slidably sleeved on the fixing rod 27, and a first spring 29 is sleeved on the fixing rod 27. The two ends of the first spring 29 are fixedly connected to the L-shaped locking rod 28 and the inner wall of the locking groove, respectively, providing a certain elastic support for the L-shaped locking rod 28.
[0037] In this invention, the cover plate 10 is provided with an observation port, and a transparent glass plate 26 is fixedly inserted into the observation port to facilitate viewing the internal condition of the main box 3. A discharge pipe 11 is fixedly inserted into the bottom of the inner wall of one side of the main box 3, and a discharge valve 12 is threadedly connected to the discharge pipe 11 to facilitate the discharge of materials. Multiple temperature sensors 13 and electric heating plates 14 are fixedly connected to the inner wall of the main box 3 for monitoring the temperature inside the main box 3 and for heating.
[0038] In this invention, a filter frame 15 is slidably inserted into the main housing 3 for purifying biological proteins. Multiple positioning blocks 16 are fixedly connected to the bottom of the main housing 3. The bottom of the filter frame 15 is provided with positioning grooves corresponding to the positioning blocks 16 to facilitate fixing the filter frame 15. A clamping mechanism is fixedly connected to the top of the filter frame 15. The inner wall of the main housing 3 is provided with slots corresponding to the clamping mechanism to fix the filter frame 15.
[0039] In this invention, the clamping mechanism includes a clamping block 30, a clamping rod 31 is slidably inserted on the clamping block 30, a clamping sleeve 32 is fixedly sleeved on one end of the clamping rod 31 near the main housing 3, and a pull rod 33 is fixedly connected to the other end of the clamping rod 31 away from the clamping sleeve 32 for easy pulling of the clamping rod 31. A second spring 34 is sleeved on the clamping rod 31, and the two ends of the second spring 34 are fixedly connected to the clamping sleeve 32 and the clamping block 30 respectively, providing a certain elastic support for the clamping rod 31. A support rod 17 is fixedly connected to the inner top of the filter frame 15, and a second motor 18 is fixedly connected to the support rod 17. A rotating rod 19 is fixedly connected to the output end of the second motor 18 for driving the spiral stirring belt 20 to rotate. The spiral stirring belt 20 is wrapped around the rotating rod 19.
[0040] In this invention, the output terminals of temperature sensor 13 and power supply 8 are both connected to the input terminal of controller 5. The output terminal of controller 5 is connected to the input terminals of memory 6, first motor 9, second motor 18 and heating plate 14 respectively, for controlling the first motor 9, second motor 18 and heating plate 14. The output terminals of communication module 7 and touch screen 4 are both connected to the input terminal of controller 5. A power connector 22 is fixedly embedded on the outer wall of control box 2. The output terminal of power connector 22 is connected to the input terminal of power supply 8 for convenient charging of power supply 8.
[0041] In this invention, the temperature sensor 13 can monitor the temperature inside the main chamber 3 and then send the monitoring signal to the controller 5. The controller 5 controls the heating plate 14 to start according to a preset threshold to heat the material inside the main chamber 3. The communication module 7 can receive or send remote control commands, and the touch screen 4 can display data and input control commands. The material can be introduced into the filter frame 15 through the feed port. Then, the first motor 9 is started to drive the main chamber 3 to rotate and centrifuge and purify the biological protein. At the same time, the second motor 18 is started to drive the rotating rod 19 to rotate, thereby driving the spiral stirring belt 20 to stir the material and improve the purification efficiency. Meanwhile, the clamping mechanism can be set to facilitate the fixing and disassembly of the filter frame 15, and the locking mechanism can facilitate the fixing of the cover plate 10.
[0042] In this invention, by setting up a monitoring and control mechanism, the purification equipment can be remotely and automatically controlled, thereby effectively improving the performance of the biological protein purification equipment.
[0043] The above description is only a preferred embodiment of the present invention, but the scope of protection of the present invention is not limited thereto. Any equivalent substitutions or modifications made by those skilled in the art within the scope of the technology disclosed in the present invention, based on the technical solution and inventive concept of the present invention, should be covered within the scope of protection of the present invention.
Claims
1. An AI-based intelligent biological protein purification device, comprising a base (1), a control box (2), and a main body (3), characterized in that, The control box (2) is fixedly connected to the top of the base (1). A touch screen (4) is fixedly connected to the outer wall of the control box (2). The control box (2) contains a controller (5), a memory (6), a communication module (7), and a power supply (8). A first motor (9) is fixedly connected to the top of the base (1). The output end of the first motor (9) is fixedly connected to the bottom of the main body (3). A support mechanism is fixedly connected to the bottom of the main body (3). The main housing (3) has a feed inlet at the top, and a cover plate (10) is slidably inserted into the feed inlet. One end of the cover plate (10) passes through the inner wall of the feed inlet and extends outward. The outer wall of the main housing (3) is provided with a locking mechanism corresponding to the cover plate (10). A discharge pipe (11) is fixedly inserted into the bottom of the inner wall of one side of the main housing (3). A discharge valve (12) is threaded onto the discharge pipe (11). Multiple temperature sensors (13) and electric heating plates (14) are fixedly connected to the inner wall of the main housing (3). A filter frame (15) is slidably inserted inside the main box (3). Multiple positioning blocks (16) are fixedly connected to the bottom of the main box (3). The bottom of the filter frame (15) is provided with a positioning groove corresponding to the positioning block (16). A clamping mechanism is fixedly connected to the top of the filter frame (15). A slot corresponding to the clamping mechanism is provided on the inner wall of the main box (3). A support rod (17) is fixedly connected to the top of the filter frame (15). A second motor (18) is fixedly connected to the support rod (17). A rotating rod (19) is fixedly connected to the output end of the second motor (18). A spiral stirring belt (20) is arranged around the rotating rod (19). The output terminals of the temperature sensor (13) and the power supply (8) are both connected to the input terminal of the controller (5). The output terminal of the controller (5) is connected to the input terminals of the memory (6), the first motor (9), the second motor (18) and the heating plate (14), respectively. The output terminals of the communication module (7) and the touch screen (4) are both connected to the input terminal of the controller (5).
2. The AI-based intelligent biological protein purification device according to claim 1, characterized in that, The bottom of the base (1) is rotatably connected to multiple universal self-locking wheels (21).
3. The AI-based intelligent biological protein purification device according to claim 1, characterized in that, A power connector (22) is fixedly embedded on the outer wall of the control box (2), and the output end of the power connector (22) is connected to the input end of the power supply (8).
4. The AI-based intelligent biological protein purification device according to claim 1, characterized in that, The support mechanism includes a plurality of symmetrically arranged slide rods (23), the bottom of which is fixedly connected to a slider (24), and the top of the base (1) is provided with an annular slide rail corresponding to the slider (24).
5. The AI-based intelligent biological protein purification device according to claim 4, characterized in that, Multiple steel balls (25) are slidably connected inside the annular slide rail, and the edges of the steel balls (25) are in contact with the slider (24).
6. The AI-based intelligent biological protein purification device according to claim 1, characterized in that, The cover plate (10) is provided with an observation port, and a transparent glass plate (26) is fixedly inserted into the observation port.
7. The AI-based intelligent biological protein purification device according to claim 1, characterized in that, The locking mechanism includes a fixed rod (27), an L-shaped locking rod (28) is slidably sleeved on the fixed rod (27), and a first spring (29) is sleeved on the fixed rod (27). The two ends of the first spring (29) are fixedly connected to the L-shaped locking rod (28) and the inner wall of the locking groove, respectively.
8. The AI-based intelligent biological protein purification device according to claim 1, characterized in that, The clamping mechanism includes a clamping block (30), on which a clamping rod (31) is slidably inserted. A sleeve (32) is fixedly sleeved at one end of the clamping rod (31) near the main housing (3), and a pull rod (33) is fixedly connected at the other end of the clamping rod (31) away from the sleeve (32).
9. The AI-based intelligent biological protein purification device according to claim 8, characterized in that, A second spring (34) is sleeved on the lever (31), and the two ends of the second spring (34) are fixedly connected to the sleeve (32) and the block (30) respectively.