Temperature-sensitive enhanced composite hydrogel as well as preparation method and application thereof
By combining triblock copolymers with hydroxybutyl chitosan, a stable three-dimensional network structure is formed, which solves the performance deficiencies of existing thermosensitive materials and realizes a thermosensitive enhanced composite hydrogel with high mechanical strength, temperature responsiveness and biocompatibility, which is suitable for drug controlled release and tissue engineering.
CN121930636APending Publication Date: 2026-04-28SUZHOU BOCHUANG TONGKANG PHARM TECH CO LTD
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Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- SUZHOU BOCHUANG TONGKANG PHARM TECH CO LTD
- Filing Date
- 2026-01-27
- Publication Date
- 2026-04-28
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Figure CN121930636A_ABST
Abstract
The invention provides temperature-sensitive enhanced composite hydrogel as well as a preparation method and application thereof. The temperature-sensitive enhanced composite hydrogel is prepared from the following raw materials: a triblock copolymer, hydroxybutyl chitosan and an aqueous medium. According to the invention, the synthetic polymer material and the natural biopolymer derivative are compounded, so that the defects of a single-component material are overcome, the mechanical strength and stability of the hydrogel are remarkably improved, and the prepared hydrogel has good biocompatibility and degradability.
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