Sample processing system

Abstract

The invention discloses a sample processing system, which is characterized in that a control device responds to an acquired redissolution instruction, and controls a pipetting needle to execute a first puncture action and a redissolution solution separate injection action on one of at least two standard sample containers loaded with a freeze-dried standard sample or a freeze-dried reagent; the pipetting needle is controlled to be separated from the standard sample container completing the reconstitution fluid separate injection action, and the cleaning device is controlled to execute a cleaning action on the pipetting needle completing the reconstitution fluid separate injection action; the pipetting needle can execute a first puncture action and a reconstitution fluid separate injection action on the other standard sample container in the at least two standard sample containers loaded with the freeze-drying standard sample or the freeze-drying reagent, so that the volume of the reconstitution fluid injected into the standard sample container by the pipetting needle is accurately controlled, and the pipetting needle can be repeatedly used; frequent replacement is not needed, and the measurement cost of the liquid standard sample of the sample treatment system is reduced.

Description

Technical Field

[0001] This application relates to the field of in vitro diagnostic equipment technology, and more particularly to a sample processing system. Background Technology

[0002] In related technologies, to achieve a longer shelf life, standard samples such as quality control products and calibrators are generally produced in lyophilized form (e.g., lyophilized powder) and stored in standard sample containers. Before instrumental analysis, the lyophilized quality control products, lyophilized reagents, or lyophilized calibrators are manually reconstituted: specifically, a certain volume of reconstitution solution is injected into the container using a syringe to reconstitute the lyophilized quality control products, lyophilized reagents, or lyophilized calibrators into a liquid state. Although automated reconstitution devices exist, they suffer from high cost and complex structure. Summary of the Invention

[0003] This application provides a sample processing system designed to address the problems of high cost and complex structure of automatic reconstitution devices in related technologies.

[0004] This application provides a sample processing system, including:

[0005] A reconstitution device includes a pipette with a puncture function. The pipette is at least used to perform a first puncture action on a standard sample container containing a lyophilized standard sample or a lyophilized reagent to make the standard sample container connected to the external environment. The pipette is also used to perform a reconstitution solution dispensing action on the standard sample container after the first puncture action is completed, so as to reconstitute the lyophilized standard sample into a liquid standard sample or the lyophilized reagent into a liquid reagent through the reconstitution solution.

[0006] A cleaning device is used to perform a cleaning action on the pipette after the reconstitution solution dispensing action has been completed;

[0007] A control device configured to respond to a received reconstitution command, the reconstitution command including reconstitution of the lyophilized standard sample or lyophilized reagent loaded in at least two standard sample containers;

[0008] The pipetting is controlled to perform the first puncture action on one of the at least two standard sample containers containing lyophilized standard samples or lyophilized reagents;

[0009] The pipetting is controlled to perform the reconstitution dispensing action on the standard sample container after the first puncture action is completed;

[0010] Control the pipette to leave the standard sample container after completing the reconstitution dispensing action;

[0011] The cleaning device is controlled to perform a cleaning action on the pipette after the reconstitution solution dispensing action is completed;

[0012] The pipetting operation, which controls the completion of the cleaning action, is performed on another of the at least two standard sample containers containing lyophilized standard samples or lyophilized reagents to perform the first puncture action.

[0013] The pipetting is controlled to perform a reconstitution dispensing action on another of the standard sample containers after the first puncture is completed.

[0014] In some embodiments, the reconstitution apparatus further includes a tubing assembly in communication with the pipette, the tubing assembly being loaded with at least a portion of the system liquid, and the tubing assembly being used at least to perform an air aspiration action on the pipette to form an isolation air column between the system liquid and the tip of the pipette;

[0015] Before the control device performs the first puncture action on one of the at least two standard sample containers containing lyophilized standard samples or lyophilized reagents, the control device is configured to:

[0016] The control tubing assembly performs an air aspiration action on the pipette.

[0017] In some embodiments, the piping assembly includes a first liquid passage, a first power unit, and a first control valve. The two ends of the first liquid passage are respectively connected to the first power unit and the pipette needle. The first control valve is disposed in the first liquid passage and is at least used to perform a closing action on the first liquid passage so that the first liquid passage is in an open state. The first power unit is at least used to perform a pulling action on at least a portion of the first liquid passage connected thereto so that the at least a portion of the first liquid passage is in a negative pressure state.

[0018] Before the control device performs the first puncture action on one of the at least two standard sample containers containing lyophilized standard samples or lyophilized reagents, the control device is configured to:

[0019] Control the first control valve to close the first liquid circuit;

[0020] The first power unit is controlled to perform a pulling action on a portion of the first fluid passage between the first power unit and the first control valve.

[0021] In some embodiments, the first control valve is at least used to perform an opening action on the first liquid passage so that the first liquid passage is in a connected state;

[0022] After the control device performs the first puncture action on one of the at least two standard sample containers containing lyophilized standard samples or lyophilized reagents, the control device is configured to:

[0023] The first control valve is controlled to open the first liquid circuit.

[0024] In some embodiments, the piping assembly further includes a system fluid container for loading system fluid, a second fluid passage, and a second control valve. One end of the second fluid passage is connected to the system fluid container, and the other end of the second fluid passage is connected to the first power component and the first fluid passage, respectively. The second control valve is disposed in the second fluid passage and is used at least to perform a closing action on the second fluid passage so that the second fluid passage is in an open state.

[0025] Before the control device performs a pulling action on a portion of the first fluid path between the first power unit and the first control valve, the control device is configured to:

[0026] The second control valve is controlled to close the second liquid circuit.

[0027] In some embodiments, the cleaning device includes a first cleaning component, the first cleaning component including a cleaning fluid container filled with cleaning fluid, a third fluid passage and a cleaning swab, one end of the third fluid passage communicating with the cleaning fluid container, the other end of the third fluid passage communicating with the cleaning swab, the third fluid passage being filled with at least a portion of the cleaning fluid, the cleaning swab having a receiving space for the pipette to enter and exit, such that the outer wall of the pipette contacts the cleaning swab, and the first power component being at least used to perform a pushing action on the third fluid passage, so that the cleaning fluid filled in the third fluid passage flows to the cleaning swab;

[0028] The control of the cleaning device to perform a cleaning action on the pipette after the completion of the reconstitution dispensing action includes:

[0029] After the reconstitution solution dispensing operation is completed, the pipette enters the receiving space;

[0030] Control the first power unit to perform a pushing action on the third hydraulic circuit;

[0031] After the reconstitution solution dispensing action is completed, the pipette leaves the receiving space;

[0032] The cleaning fluid container and the system fluid container are the same container, or the cleaning fluid container and the system fluid container are two independent containers.

[0033] In some embodiments, the first cleaning component further includes a third control valve, which is disposed in the third liquid passage and is at least used to perform a closing action on the third liquid passage so that the third liquid passage is in a connected state;

[0034] Before the first power unit performs a pushing action on the third liquid path, the control device is configured to:

[0035] The third control valve is controlled to close the third liquid circuit.

[0036] In some embodiments, the cleaning device includes a second cleaning component, the second cleaning component including a cleaning tank filled with cleaning fluid, and the first power component is at least used to perform a cleaning fluid aspiration action on the pipette inserted into the cleaning tank, so that the cleaning fluid enters the inner cavity of the pipette; the first power component is also at least used to perform a cleaning fluid dispensing action on the pipette inserted into the cleaning tank, so that the cleaning fluid flows out from the inner cavity of the pipette.

[0037] The control of the cleaning device to perform a cleaning action on the pipette after the completion of the reconstitution dispensing action includes:

[0038] After the reconstitution solution dispensing operation is completed, the pipette is inserted into the cleaning tank;

[0039] The first power unit is controlled to perform a cleaning fluid aspiration action on the pipette inserted into the cleaning tank;

[0040] The first power unit is controlled to perform a dispensing action of cleaning fluid to the pipette inserted into the cleaning tank.

[0041] In some embodiments, the cleaning apparatus further includes a waste liquid treatment component, which includes a waste liquid tank for loading contaminated cleaning liquid, a second power component, a fourth liquid path, a fifth liquid path, a sixth liquid path, and a fourth control valve. One end of the fourth liquid path is connected to the waste liquid tank, and the other end of the fourth liquid path is connected to the fourth control valve. One end of the fifth liquid path is connected to the cleaning tank, and the other end of the fifth liquid path is connected to the fourth control valve. One end of the sixth liquid path is connected to the cleaning swab, and the other end of the sixth liquid path is connected to the fourth control valve. The second power component is disposed in the fourth liquid path. The fourth control valve has a first state in which the fourth liquid path is connected to the fifth liquid path and a second state in which the fourth liquid path is connected to the sixth liquid path. The second power component is at least used to provide power to recover the contaminated cleaning liquid in the cleaning tank in the first state, and the second power component is also used to provide power to recover the contaminated cleaning liquid in the cleaning swab in the second state. Preferably, the sixth liquid path is provided with a filter for filtering the contaminated cleaning liquid.

[0042] In some embodiments, the reconstitution device further includes a reconstitution container containing the reconstitution solution, and the pipette is at least further used to perform a second puncture on the standard sample container after the first puncture action is completed, so as to at least partially penetrate the standard sample container;

[0043] After the control device performs a first puncture operation on one of the at least two standard sample containers containing lyophilized standard samples or lyophilized reagents, and before the control device performs the reconstitution dispensing operation on the standard sample container after the first puncture operation, the control device is configured as follows:

[0044] Control the pipette to leave the standard sample container after the first puncture action has been completed;

[0045] Control the pipette to draw at least a portion of the reconstituted solution from the reconstituted solution container;

[0046] The pipetting is controlled to perform a second puncture on the standard sample container after the first puncture action has been completed.

[0047] In some embodiments, after the control of the pipette leaving the standard sample container where the first puncture action was completed and before the control of the pipette drawing at least a portion of the reconstitution solution from the reconstitution container, the control device is configured to:

[0048] The cleaning device is controlled to perform a cleaning action on the pipette after the first puncture is completed.

[0049] In some embodiments, the outer wall of the pipette is provided with a groove extending along the length of the pipette. The standard sample container includes a bottle body and a cap. The bottle body forms an inner cavity, which is used to contain lyophilized standard samples and liquid standard samples reconstituted from the lyophilized standard samples, or the inner cavity is used to contain lyophilized reagents and liquid reagents reconstituted from the lyophilized reagents. The cap seals the inner cavity. When the pipette completes the first puncture action, a venting channel is formed between the groove and the cap, and the inner cavity is connected to the external environment through the venting channel to achieve pressure relief of the inner cavity. When the pipette completes the second puncture action, the venting channel is formed between the groove and the cap to allow the reconstituted solution to be injected into the inner cavity.

[0050] In some embodiments, the lyophilized standard sample is a lyophilized quality control sample, or the lyophilized standard sample is a lyophilized calibrator.

[0051] The sample processing system provided in this application embodiment responds to a reconstitution command via a control device. After the control device performs a first puncture and reconstitution dispensing action on one of at least two standard sample containers containing lyophilized standard samples or lyophilized reagents, it controls the pipette to separate from the standard sample container after the reconstitution dispensing action. A cleaning device then cleans the pipette after the reconstitution dispensing action, enabling the pipette to perform the first puncture and reconstitution dispensing action on the other of the at least two standard sample containers containing lyophilized standard samples or lyophilized reagents. This allows the pipette to puncture a sealed sample container and simultaneously inject the reconstitution solution into the standard sample container. Furthermore, the pipette is reusable, eliminating the need for frequent replacements and reducing the structural complexity of the sample processing system. Attached Figure Description

[0052] The technical solution and other beneficial effects of this application will become apparent from the following detailed description of specific embodiments in conjunction with the accompanying drawings.

[0053] Figure 1 A schematic diagram of the structure of one embodiment of the sample processing system provided in this application;

[0054] Figure 2 for Figure 1 Enlarged view of point A in the middle;

[0055] Figure 3 A schematic diagram of one embodiment of the sample processing system provided in this application;

[0056] Figure 4 This is a schematic diagram showing the state of the pipette performing the first puncture action according to an embodiment of this application;

[0057] Figure 5 This is a schematic diagram of the structure of the pipette provided in this application embodiment after the first puncture action is performed, showing the system fluid moving a certain distance toward the nozzle of the pipette;

[0058] Figure 6 A schematic diagram of the structure provided in this application embodiment, showing the pipette and the system liquid and reconstitution solution in the first liquid path separated by air;

[0059] Figure 7 This is a schematic diagram of the structure of the pipette after performing the rehydration solution dispensing action according to an embodiment of this application;

[0060] Figure 8 This is a schematic diagram of one embodiment of the pipette provided in this application.

[0061] Sample processing system 10; reconstitution device 11; pipette 111; groove 1111; tubing assembly 112; first liquid passage 1121; first power unit 1122; first control valve 1123; system liquid container 1124; second liquid passage 1125; second control valve 1126; isolation gas column 1127; cleaning device 12; first cleaning component 121; cleaning liquid container 122; third liquid passage 123; cleaning swab 124; accommodating space 1241; third control valve 125; second cleaning component 126; cleaning tank 1261; waste liquid treatment component 13; waste liquid tank 131; second power unit 132; fourth liquid passage 133; fifth liquid passage 134; sixth liquid passage 135; fourth control valve 136; filter 137; standard sample container 14; bottle body 141; inner cavity 1411; cap 142; system liquid 20; reconstitution solution 30. Detailed Implementation

[0062] The technical solutions of the embodiments of this application will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only a part of the embodiments of this application, and not all of them. All other embodiments obtained by those skilled in the art based on the embodiments of this application without creative effort are within the scope of protection of this application.

[0063] In the description of this application, it should be understood that the terms "center," "longitudinal," "lateral," "length," "width," "thickness," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," "clockwise," and "counterclockwise," etc., indicating orientation or positional relationships based on the orientation or positional relationships shown in the accompanying drawings, are only for the convenience of describing this application and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this application. Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of indicated technical features. Thus, features defined with "first" and "second" may explicitly or implicitly include one or more of the stated features. In the description of this application, "a plurality of" means two or more, unless otherwise explicitly specified.

[0064] In the description of this application, it should be noted that, unless otherwise expressly specified and limited, the terms "installation," "connection," and "linking" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection, an electrical connection, or a connection that allows communication between them; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication between two components or the interaction between two components. Those skilled in the art can understand the specific meaning of the above terms in this application according to the specific circumstances.

[0065] In this application, unless otherwise expressly specified and limited, "above" or "below" the second feature can include direct contact between the first and second features, or contact between the first and second features through another feature between them. Furthermore, "above," "over," and "on top" of the second feature includes the first feature being directly above or diagonally above the second feature, or simply indicates that the first feature is at a higher horizontal level than the second feature. "Below," "below," and "under" the second feature includes the first feature being directly below or diagonally below the second feature, or simply indicates that the first feature is at a lower horizontal level than the second feature.

[0066] The following disclosure provides many different embodiments or examples for implementing different structures of this application. To simplify the disclosure, specific examples of components and arrangements are described below. Of course, these are merely examples and are not intended to limit the scope of this application. Furthermore, reference numerals and / or letters may be repeated in different examples; such repetition is for simplification and clarity and does not in itself indicate a relationship between the various embodiments and / or arrangements discussed. In addition, examples of various specific processes and materials are provided in this application, but those skilled in the art will recognize the application of other processes and / or the use of other materials.

[0067] This application provides a sample processing system. The following provides a detailed description of each system.

[0068] Figure 1 This is a schematic diagram of one embodiment of the sample processing system provided in this application. Figure 2 for Figure 1 Enlarged view of point A in the middle. Figure 3 This is a schematic diagram of one embodiment of the sample processing system provided in this application. Figures 1 to 3 As shown, the sample processing system 10 includes a reconstitution device 11, which includes a pipette 111 with a puncture function. The pipette 111 is used to puncture a standard sample container 14 containing lyophilized standard samples and inject a reconstitution solution 30 into the standard sample container 14 to reconstitute the lyophilized standard samples in the standard sample container 14 into a liquid standard sample. The lyophilized standard sample or lyophilized reagent can be a lyophilized quality control sample. Alternatively, the lyophilized standard sample can be a lyophilized calibrator.

[0069] Since the lyophilized standard samples are prepared under lyophilization conditions of low temperature and low pressure, the pressure in the standard sample container 14 is consistent with the operating pressure during lyophilization, close to the absolute pressure of 0 kPa, while the pressure in the reconstitution device 11 is close to atmospheric pressure. If the pipette 111 is directly used to puncture the standard sample container 14 containing the lyophilized standard sample and the reconstitution solution 30 is injected into the standard sample container 14, the large pressure difference between the standard sample container 14 and the reconstitution device 11 will cause the reconstitution solution 30 in the reconstitution device 11 to flow into the standard sample container 14 prematurely. This results in an uncontrollable and inaccurate volume of the reconstitution solution 30 injected into the standard sample container 14, which in turn affects the consistency of the liquid standard sample formed by the reconstitution of the lyophilized standard sample.

[0070] In some embodiments, the pipette 111 of the reconstitution device 11 may be used at least to perform a first puncture action on the standard sample container 14 containing the lyophilized standard sample to connect the standard sample container 14 with the external environment, allowing air from the external environment to enter the standard sample container 14 to balance the pressure inside the standard sample container 14, so that the pressure inside the standard sample container 14 is basically consistent with the pressure of the external environment where the reconstitution device 11 is located. This avoids the problem that a large pressure difference between the standard sample container 14 and the reconstitution device 11 leads to an uncontrollable and inaccurate volume of the reconstitution solution 30 injected into the standard sample container 14 by the reconstitution device 11.

[0071] like Figure 4 and Figure 8 As shown, the standard sample container 14 includes a bottle body 141 and a cap 142. The bottle body 141 forms an inner cavity 1411, which is used to contain lyophilized standard samples and liquid standard samples formed by reconstitution of lyophilized standard samples. The cap 142 seals the inner cavity 1411. A pipette 111 is used to puncture the cap 142 of the standard sample container 14 containing lyophilized standard samples to complete the first puncture action.

[0072] The pipette 111 may have a groove 1111 on its outer wall. The groove 1111 extends along the length of the pipette 111. When the pipette 111 completes the first puncture, a venting channel is formed between the groove 1111 of the pipette 111 and the cap 142. The inner cavity 1411 is connected to the external environment through the venting channel, so that air from the external environment can enter the standard sample container 14 to balance the pressure inside the standard sample container 14 and realize the depressurization of the inner cavity 1411.

[0073] In other embodiments, the pipette 111 may be removed from the cap 142 after performing the first puncture, allowing the standard sample container 14 to communicate with the external environment through the through-hole formed by the puncture in the cap 142. Alternatively, after the pipette 111 performs the first puncture, the standard sample container 14 may be directly connected to the external environment through the pipette 111.

[0074] In some embodiments, the pipette 111 of the reconstitution device 11 is also used to perform a reconstitution solution dispensing action on the standard sample container 14 after the first puncture action, so as to reconstitute the lyophilized standard sample into a liquid standard sample using the reconstitution solution 30. Since the operation of the pipette 111 injecting the reconstitution solution 30 into the standard sample container 14 occurs after the pipette 111 performs the first puncture action, the pressure inside the standard sample container 14 is basically the same as the pressure of the reconstitution device 11, and the volume of the reconstitution solution 30 injected into the standard sample container 14 by the pipette 111 can be precisely controlled, which is beneficial to improving the consistency of the lyophilized standard sample or lyophilized reagent reconstituted into a liquid standard sample in the standard sample container 14.

[0075] Those skilled in the art will understand that the solution of this embodiment can also be applied to the reconstitution operation of lyophilized reagents. It is understood that the sample container, as a carrier, can also contain lyophilized reagents, in which case the reconstitution solution will reconstitute the lyophilized reagents to form a liquid reagent. Since the production conditions of lyophilized reagents are also lyophilization-based, involving low temperature and low pressure, similar technical problems exist.

[0076] In some embodiments, the sample processing system 10 may further include a cleaning device 12 for cleaning the pipette 111 after the reconstitution dispensing operation, so that the pipette 111 can perform a first puncture and reconstitution dispensing operation on another standard sample container 14, thereby enabling the pipette 111 to be reused.

[0077] The sample processing system 10 may include a control device configured to respond to a reconstitution command, which includes the reconstitution of lyophilized standard samples or lyophilized reagents loaded in at least two standard sample containers 14. The reconstitution command may be a command manually input by an operator to the control device, or it may be a command automatically transmitted by the sample processing system 10 to the control device at regular intervals or when preset conditions are met.

[0078] The control device is further configured to control the pipette 111 to perform a first puncture action on one of the at least two standard sample containers 14 containing lyophilized standard samples or lyophilized reagents. Specifically, the control device can control the movement of the pipette 111 to puncture one of the at least two standard sample containers 14 containing lyophilized standard samples or lyophilized reagents, thereby completing the first puncture action. Alternatively, the control device can also control a moving mechanism to drive one of the at least two standard sample containers 14 to move relative to the pipette 111, causing the pipette 111 to puncture one of the at least two standard sample containers 14 containing lyophilized standard samples or lyophilized reagents, thereby completing the first puncture action.

[0079] The control device is also configured to control the pipette 111 to perform a reconstitution dispensing action on the standard sample container 14 after the first puncture action is completed. After the pipette 111 of the reconstitution device 11 completes the first puncture action, the control device can control the reconstitution device 11 to provide reconstitution solution 30 to the pipette 111, so that the pipette 111 injects the reconstitution solution 30 into the standard sample container 14, so as to reconstitute the lyophilized standard sample into a liquid standard sample through the reconstitution solution 30.

[0080] The control device is also configured to: control the pipette 111 to leave the standard sample container 14 after the reconstitution dispensing operation, and then control the cleaning device 12 to perform a cleaning operation on the pipette 111 after the reconstitution dispensing operation. Specifically, the control device can control the cleaning device 12 to provide cleaning fluid to the inner and outer walls of the pipette 111 after the reconstitution dispensing operation, thereby cleaning the inner and outer walls of the pipette 111 and enabling the pipette 111 to perform a first puncture and reconstitution dispensing operation on another of at least two standard sample containers 14.

[0081] The control device is also configured to: control the pipette 111, after completing the cleaning action, to perform a first puncture action on another standard sample container 14 among at least two standard sample containers 14 containing lyophilized standard samples or lyophilized reagents; and then control the pipette 111 to perform a reconstitution dispensing action on the other standard sample container 14 after the first puncture action.

[0082] The method by which the control device controls the pipette 111 to perform the first puncture action and the reconstitution dispensing action on another of the at least two standard sample containers 14 containing lyophilized standard samples or lyophilized reagents can be referred to the method described above for the control device to control the pipette 111 to perform the first puncture action and the reconstitution dispensing action on one of the standard sample containers 14 containing lyophilized standard samples or lyophilized reagents, and will not be repeated here.

[0083] The sample processing system 10 provided in this application embodiment responds to the acquired reconstitution command through a control device. After the control device performs a first puncture and reconstitution dispensing action on one of the at least two standard sample containers 14 containing lyophilized standard samples or lyophilized reagents, the control device separates the control device 111 from the standard sample container 14 that has completed the reconstitution dispensing action. The control device 12 then performs a cleaning action on the control device 111 after the reconstitution dispensing action. This allows the control device 111 to perform the first puncture and reconstitution dispensing action on the other of the at least two standard sample containers 14 containing lyophilized standard samples or lyophilized reagents. This achieves precise control of the volume of reconstitution solution 30 injected into the standard sample container 14 by the control device 111, while also enabling the control device 111 to be reused without frequent replacement, thus reducing the structural complexity of the sample processing system 10.

[0084] In some embodiments, such as Figure 3 and Figure 4As shown, the reconstitution device 11 may further include a tubing assembly 112, which is connected to a pipette 111. The tubing assembly 112 is loaded with at least a portion of the system liquid 20. The tubing assembly 112 is used at least to perform an air aspiration action on the pipette 111 so that an isolation air column 1127 is formed between the system liquid 20 and the tip of the pipette 111.

[0085] It is understandable that, due to the large pressure difference between the standard sample container 14 and the reconstitution device 11, when the pipette 111 performs the first puncture action, some of the system liquid 20 in the tubing assembly 112 may flow into the standard sample container 14 under the influence of the pressure difference, affecting the accuracy of the liquid standard sample determination.

[0086] In this embodiment, the tubing assembly 112 performs an air aspiration action on the pipette 111, forming an isolation air column 1127 between the system liquid 20 and the tip of the pipette 111. When the pipette 111 performs the first puncture action, the isolation air column 1127 isolates the system liquid 20 from the standard sample container 14. Figure 5 As shown, even if the system liquid 20 moves a certain distance toward the tip of the pipette 111, it will not enter the standard sample container 14, which helps to improve the accuracy of the determination of liquid standard samples.

[0087] Before the control device controls the pipette 111 to perform the first puncture action on one of the standard sample containers 14 containing at least two standard sample containers 14 of lyophilized standard samples or lyophilized reagents, the control device may also be configured to control the tubing assembly 112 to perform an air aspiration action on the pipette 111 to form an isolation air column 1127 between the system liquid 20 and the needle orifice of the pipette 111.

[0088] In some embodiments, such as Figure 3 As shown, the piping assembly 112 may include a first liquid passage 1121, a first power unit 1122, and a first control valve 1123. The two ends of the first liquid passage 1121 are respectively connected to the first power unit 1122 and the pipette needle 111. The first control valve 1123 is disposed in the first liquid passage 1121 and is used at least to perform a closing action on the first liquid passage 1121, so that the first liquid passage 1121 is in an open state. The first power unit 1122 is used at least to perform a pulling action on the first liquid passage 1121, so that at least a portion of the first liquid passage 1121 is in a negative pressure state. The first power unit 1122 may be a syringe, a water pump, or other component capable of placing at least a portion of the first liquid passage 1121 in a negative pressure state. The first control valve 1123 may be a solenoid valve or other control valve capable of performing a closing action on the first liquid passage 1121.

[0089] Specifically, before the control pipette 111 performs the first puncture action on one of the two standard sample containers 14 containing at least two lyophilized standard samples or lyophilized reagents, the control device is configured to: control the first control valve 1123 to perform a closing action on the first liquid passage 1121; and control the first power unit 1122 to perform a pulling action on a portion of the first liquid passage 1121 between the first power unit 1122 and the first control valve 1123, so that at least a portion of the first liquid passage 1121 is in a negative pressure state.

[0090] By placing at least a portion of the first liquid path 1121 under negative pressure before performing the first puncture on one of the two standard sample containers 14 containing lyophilized standard samples or lyophilized reagents using the pipette 111, the pressure difference between the first liquid path 1121 and the standard sample container 14 can be further reduced when the pipette 111 performs the first puncture. This helps to reduce the impact of the negative pressure in the standard sample container 14 on the system liquid 20 in the first liquid path 1121.

[0091] The first control valve 1123 is also used to open the first liquid passage 1121, so that the first liquid passage 1121 is in a connected state. After the control device controls the pipette 111 to perform a first puncture action on one of the two standard sample containers 14 containing lyophilized standard samples or lyophilized reagents, the control device can also be configured to: control the first control valve 1123 to open the first liquid passage 1121, so that the first liquid passage 1121 is connected to the standard sample container 14 through the pipette 111.

[0092] Therefore, when the pipette 111 performs the first puncture action, it can more quickly balance the pressure in the first liquid path 1121 and the standard sample container 14, reducing the risk that the negative pressure in the standard sample container 14 will cause the first liquid path 1121 to contract and deform when the pipette 111 performs the first puncture action, which may lead to the system liquid 20 in the first liquid path 1121 precipitating into the standard sample container 14.

[0093] Continue to refer to Figure 3 The piping assembly 112 may further include a system fluid container 1124 for containing system fluid 20, a second fluid passage 1125, and a second control valve 1126. One end of the second fluid passage 1125 is connected to the system fluid container 1124, and the other end of the second fluid passage 1125 is connected to the first power component 1122 and the first fluid passage 1121, respectively. The second control valve 1126 is disposed in the second fluid passage 1125 and is used at least to perform a closing action on the second fluid passage 1125, so that the second fluid passage 1125 is in an open state. The first control valve 1123 may be a solenoid valve or other control valve capable of performing a closing action on the second fluid passage 1125.

[0094] Before the control device controls the first power unit 1122 to perform a pulling action on a portion of the first liquid passage 1121 between the first power unit 1122 and the first control valve 1123, the control device can also be configured to control the second control valve 1126 to perform a closing action on the second liquid passage 1125. This avoids the problem that when the first power unit 1122 performs a pulling action on a portion of the first liquid passage 1121 between the first power unit 1122 and the first control valve 1123, the system liquid 20 in the system liquid container 1124 is not drawn into the first power unit 1122, thus preventing the formation of negative pressure in at least a portion of the first liquid passage 1121.

[0095] In some embodiments, the tubing of the first liquid path 1121 and the second liquid path 1125 can be made of rigid tubing, so that the deformation coefficient of the first liquid path 1121 and the second liquid path 1125 is smaller, thereby reducing the deformation of the first liquid path 1121 and the second liquid path 1125 when the pipette 111 performs the first puncture action, thereby reducing the distance that the system liquid 20 in the first liquid path 1121 moves toward the needle orifice of the pipette 111, and thus reducing the possibility of the system liquid flowing into the standard sample container 14.

[0096] In some embodiments, such as Figure 3 As shown, the cleaning device 12 may include a first cleaning component 121, which includes a cleaning fluid container 122 containing cleaning fluid, a third fluid passage 123, and a cleaning swab 124. One end of the third fluid passage 123 is connected to the cleaning fluid container 122, and the other end of the third fluid passage 123 is connected to the cleaning swab 124, thereby enabling the cleaning fluid container 122 to supply cleaning fluid to the cleaning swab 124 through the third fluid passage 123. The cleaning fluid container 122 and the system fluid container 1224 may be the same container, or they may be two independent containers.

[0097] The third fluid path 123 is filled with at least a portion of the cleaning fluid, and the cleaning swab 124 has a receiving space 1241 for the pipette 111 to enter and exit, so that the outer wall of the pipette 111 contacts the cleaning swab 124, so that the cleaning swab 124 can clean the outer wall of the pipette 111.

[0098] In some embodiments, the control device controlling the cleaning device 12 to perform a cleaning action on the pipette 111 after the reconstitution solution dispensing action may include: controlling the pipette 111 after the reconstitution solution dispensing action to enter the receiving space 1241 of the cleaning swab 124; controlling the first power unit 1122 to perform a pushing action on the third liquid path 123 so that the cleaning fluid loaded in the third liquid path 123 flows to the cleaning swab 124, thereby cleaning the outer wall of the pipette 111 through the cleaning swab 124.

[0099] The control device can control the movement of the pipette 111 relative to the cleaning swab 124 so that the pipette 111 enters the receiving space 1241 of the cleaning swab 124. Alternatively, the control device can also control the moving mechanism to drive the cleaning swab 124 to move relative to the pipette 111 so that the pipette 111 enters the receiving space 1241 of the cleaning swab 124.

[0100] In addition, the control device controlling the cleaning device 12 to perform a cleaning action on the pipette 111 after the completion of the reconstitution dispensing action may also include: controlling the pipette 111 after the completion of the reconstitution dispensing action to leave the accommodating space 1241 to complete the cleaning action of the pipette 111, so as to facilitate the pipette 111 to perform a first puncture action and a reconstitution dispensing action on another standard sample container 14 among at least two standard sample containers 14 containing lyophilized standard samples or lyophilized reagents.

[0101] In some embodiments, the first cleaning component 121 may further include a third control valve 125, which is disposed on the third liquid passage 123. The third control valve 125 is at least used to perform a closing action on the third liquid passage 123, so that the third liquid passage 123 is in a connected state. The third control valve 125 may be a solenoid valve or other control valve capable of performing a closing action on the third liquid passage 123.

[0102] Before the control device controls the first power unit 1122 to perform a pushing action on the third liquid passage 123, the control device can also be configured to control the third control valve 125 to close the third liquid passage 123, so that the first power unit 1122 can more effectively draw cleaning fluid from the cleaning fluid container 122. This also prevents the first power unit 1122 from being affected by the third liquid passage 123 when performing other actions. Finally, it also prevents the cleaning fluid in the cleaning fluid container 122 from flowing into the cleaning swab 124 through the third liquid passage 123 when the pipette 111 has not entered the receiving space 1241 of the cleaning swab 124, thus avoiding waste of cleaning fluid.

[0103] In some embodiments, such as Figure 3 As shown, the cleaning device 12 may further include a second cleaning component 126, which includes a cleaning tank 1261 containing cleaning fluid. The first power component 1122 is at least used to perform a cleaning fluid aspiration action on the pipette 111 inserted into the cleaning tank 1261, so that the cleaning fluid enters the inner cavity 1411 of the pipette 111. The first power component 1122 is also at least used to perform a cleaning fluid dispensing action on the pipette 111 inserted into the cleaning tank 1261, so that the cleaning fluid flows out from the inner cavity 1411 of the pipette 111, thereby cleaning the inner wall of the pipette 111.

[0104] The control device controlling the cleaning device 12 to perform a cleaning action on the pipette 111 after the reconstitution solution dispensing operation may include: controlling the pipette 111 after the reconstitution solution dispensing operation to be inserted into the cleaning tank 1261; controlling the first power unit 1122 to perform a cleaning solution aspiration action on the pipette 111 inserted into the cleaning tank 1261, so as to draw the cleaning solution into the pipette 111 and the first liquid passage 1121. During the process of drawing in the cleaning solution, the cleaning solution will flow through the inner cavity 1411 of the pipette 111, which can complete one cleaning of the inner wall of the pipette 111.

[0105] The control device controls the cleaning device 12 to perform a cleaning action on the pipette 111 after the reconstitution solution dispensing action is completed. This also includes controlling the first power unit 1122 to perform a cleaning fluid dispensing action on the pipette 111 inserted into the cleaning tank 1261. During this process, the cleaning fluid will flow through the inner cavity 1411 of the pipette 111 again, thereby completing a second cleaning of the inner wall of the pipette 111.

[0106] In some embodiments, such as Figure 3 As shown, the cleaning device 12 may further include a waste liquid treatment component 13, which is used to treat the cleaning liquid after cleaning the pipette 111. The waste liquid treatment component 13 also includes a waste liquid tank 131 for holding the contaminated cleaning liquid, a fourth liquid passage 133, a fifth liquid passage 134, and a fourth control valve 136. One end of the fourth liquid passage 133 is connected to the waste liquid tank 131, and the other end is connected to the fourth control valve 136. One end of the fifth liquid passage 134 is connected to the cleaning tank 1261, and the other end is connected to the fourth control valve 136. Therefore, when the fourth control valve 136 connects the fourth liquid passage 133 and the fifth liquid passage 134, the cleaning tank 1261 is connected to the waste liquid tank 131 sequentially through the fifth liquid passage 134, the fourth control valve 136, and the fourth liquid passage 133, allowing the waste liquid in the cleaning tank 1261 to be discharged into the waste liquid tank 131.

[0107] Continue to refer to Figure 3 The waste liquid treatment component 13 may further include a sixth liquid passage 135, one end of which is connected to the cleaning swab 124, and the other end of which is connected to the fourth control valve 136. When the fourth control valve 136 connects the sixth liquid passage 135 and the fourth liquid passage 133, the cleaning swab 124 is connected to the waste liquid tank 131 in sequence through the sixth liquid passage 135, the fourth control valve 136, and the fourth liquid passage 133, thereby allowing the waste liquid in the cleaning swab 124 to be discharged into the waste liquid tank 131.

[0108] Specifically, the fourth control valve 136 can be configured to have a first state in which the fourth liquid passage 133 is connected to the fifth liquid passage 134 and a second state in which the fourth liquid passage 133 is connected to the sixth liquid passage 135. When the fourth control valve 136 is in the first state, the fourth liquid passage 133 is connected to the fifth liquid passage 134. When the fourth control valve 136 is in the second state, the fourth liquid passage 133 is connected to the sixth liquid passage 135.

[0109] Continue to refer to Figure 3 The waste liquid treatment component 13 may further include a second power component 132, which is disposed in the fourth liquid passage 133. The second power component 132 is used to provide power when the fourth control valve 136 is in the first state to recover the contaminated cleaning fluid in the cleaning tank 1261, so that the contaminated cleaning fluid in the cleaning tank 1261 is discharged to the waste liquid tank 131 more quickly. In addition, the second power component 132 is also used to provide power when the fourth control valve 136 is in the second state to recover the contaminated cleaning fluid in the cleaning swab 124, so that the contaminated cleaning fluid in the cleaning swab 124 is discharged to the waste liquid tank 131 more quickly.

[0110] The second power unit 132 can be a water pump or other component capable of drawing out contaminated cleaning fluid from the cleaning swab 124 or the cleaning pool 1261; there are no restrictions on this.

[0111] In some embodiments, a filter 137 for filtering contaminated cleaning fluid may be provided in the sixth liquid path 135, thereby preventing impurities in the contaminated cleaning fluid from entering the second power component 132 and causing damage to the second power component 132.

[0112] In some embodiments, the reconstitution device 11 may further include a reconstitution container containing reconstitution solution 30, and the pipette 111 is at least used to perform a second puncture on the standard sample container 14 after the first puncture action is completed, so as to at least partially penetrate the standard sample container 14, thereby injecting the reconstitution solution 30 into the standard sample container 14 after the gas pressure is balanced.

[0113] When the pipette 111 completes the second puncture, a venting channel is formed between the groove 1111 and the cap 142. Therefore, during the process of injecting the reconstitution solution 30 into the standard sample container 14, the gas inside the standard sample container 14 can be expelled through the venting channel, thus preventing excessive gas pressure inside the standard sample container 14 from affecting the speed at which the pipette 111 injects the reconstitution solution 30 into the standard sample container 14.

[0114] In some embodiments, the depth to which the pipette 111 is inserted into the cap 142 can satisfy the following: the height of the pipette 111 tip is higher than the liquid level of the liquid standard sample in the standard sample container 14, while the groove 1111 of the pipette 111 remains in communication with the inside of the standard sample container 14, so that the pipette 111 can quickly inject the reconstitution solution 30 into the standard sample container 14, while the pipette 111 will not come into contact with the liquid standard sample, so as to ensure the consistency of the liquid standard sample.

[0115] In some implementations, after the control device controls the pipette 111 to perform a first puncture on one of at least two standard sample containers 14 containing lyophilized standard samples or lyophilized reagents, and before controlling the pipette 111 to perform a reconstitution dispensing action on the standard sample container 14 after the first puncture, the control device may also be configured to: control the pipette 111 to leave the standard sample container 14 after the first puncture; control the pipette 111 to aspirate at least a portion of the reconstitution solution 30 from the reconstitution container; and control the pipette 111 to perform a second puncture on the standard sample container 14 after the first puncture.

[0116] Among them, such as Figure 6 As shown, the control device can control the first power unit 1122 to perform a pulling action on the first liquid path 1121, so that the cleaning liquid or system liquid 20 in the first liquid path 1121 moves a certain distance away from the needle opening of the pipette 111, and then controls the pipette 111 to be inserted into the reconstitution container and draw at least a portion of the reconstitution solution 30 from the reconstitution container, so that the cleaning liquid or system liquid 20 in the first liquid path 1121 and the reconstitution solution 30 are isolated by air, which helps to improve the accuracy of the reconstitution device 11 in controlling the volume of reconstitution solution 30 drawn and discharged.

[0117] During the dispensing of the reconstituted solution, the first power unit 1122 can be controlled to perform a pushing action on the first liquid passage 1121, thereby pushing the pipette needle 111 and the reconstituted solution 30 within the first liquid passage 1121 toward the needle orifice and dispensing it into the standard sample container 14. After dispensing is completed, as follows: Figure 7 As shown, the cleaning solution or system liquid 20 in the pipette 111 and the first liquid path 1121 is kept at a certain distance from the nozzle of the pipette 111 to prevent the cleaning solution or system liquid 20 from entering the standard sample container 14.

[0118] In some embodiments, after the control device controls the pipette 111 to leave the standard sample container 14 after the first puncture action is completed, and before the control device controls the pipette 111 to draw at least a portion of the reconstituted solution 30 from the reconstituted solution container, the control device may also be configured to control the cleaning device 12 to perform a cleaning action on the pipette 111 after the first puncture action is completed.

[0119] In this embodiment of the application, the control device may be a controller or other device capable of controlling the above-mentioned components to perform corresponding actions, and there is no limitation here.

[0120] In the above embodiments, the descriptions of each embodiment have different focuses. For parts not described in detail in a certain embodiment, please refer to the relevant descriptions in other embodiments.

[0121] The above provides a detailed description of a sample processing system provided in the embodiments of this application. Specific examples have been used to illustrate the principles and implementation methods of this application. The description of the above embodiments is only for the purpose of helping to understand the technical solutions and core ideas of this application. Those skilled in the art should understand that modifications can still be made to the technical solutions described in the foregoing embodiments, or equivalent substitutions can be made to some of the technical features. These modifications or substitutions do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of this application.

Claims

1. A sample processing system, characterized in that, include: A reconstitution device includes a pipette with a puncture function. The pipette is at least used to perform a first puncture action on a standard sample container containing a lyophilized standard sample or a lyophilized reagent to make the standard sample container connected to the external environment. The pipette is also used to perform a reconstitution solution dispensing action on the standard sample container after the first puncture action is completed, so as to reconstitute the lyophilized standard sample into a liquid standard sample or reconstitute the lyophilized reagent into a liquid reagent. A cleaning device, wherein the cleaning device is used to perform a cleaning action on the pipette after the reconstitution solution dispensing action is completed; A control device configured to respond to a received reconstitution command, the reconstitution command including reconstitution of the lyophilized standard sample or lyophilized reagent loaded in at least two standard sample containers; The pipetting is controlled to perform the first puncture action on one of the at least two standard sample containers containing lyophilized standard samples or lyophilized reagents; The pipetting is controlled to perform the reconstitution dispensing action on the standard sample container after the first puncture action is completed; Control the pipette to leave the standard sample container after completing the reconstitution dispensing action; The cleaning device is controlled to perform a cleaning action on the pipette after the reconstitution solution dispensing action is completed; The pipetting operation, which controls the completion of the cleaning action, is performed on another of the at least two standard sample containers containing lyophilized standard samples or lyophilized reagents to perform the first puncture action. The pipetting is controlled to perform a reconstitution dispensing action on another of the standard sample containers after the first puncture is completed.

2. The sample processing system as described in claim 1, characterized in that, The reconstitution device further includes a tubing assembly connected to the pipette, the tubing assembly being loaded with at least a portion of the system liquid, and the tubing assembly being used at least to perform an air aspiration action on the pipette to form an isolation air column between the system liquid and the tip of the pipette. Before the control device performs the first puncture action on one of the at least two standard sample containers containing lyophilized standard samples or lyophilized reagents, the control device is configured to: The control tubing assembly performs an air aspiration action on the pipette.

3. The sample processing system as described in claim 2, characterized in that, The piping assembly includes a first liquid passage, a first power unit, and a first control valve. The two ends of the first liquid passage are respectively connected to the first power unit and the pipette needle. The first control valve is disposed in the first liquid passage. The first control valve is at least used to perform a closing action on the first liquid passage so that the first liquid passage is in an open state. The first power unit is at least used to perform a pulling action on at least a portion of the first liquid passage connected to it so that the at least a portion of the first liquid passage is in a negative pressure state. Before the control device performs the first puncture action on one of the at least two standard sample containers containing lyophilized standard samples or lyophilized reagents, the control device is configured to: Control the first control valve to close the first liquid circuit; The first power unit is controlled to perform a pulling action on a portion of the first fluid passage between the first power unit and the first control valve.

4. The sample processing system as described in claim 3, characterized in that, The first control valve is also used to open the first liquid passage so that the first liquid passage is in a connected state; After the control device performs the first puncture action on one of the at least two standard sample containers containing lyophilized standard samples or lyophilized reagents, the control device is configured to: The first control valve is controlled to open the first liquid circuit.

5. The sample processing system as described in claim 3, characterized in that, The piping assembly further includes a system liquid container for loading system liquid, a second liquid passage, and a second control valve. One end of the second liquid passage is connected to the system liquid container, and the other end of the second liquid passage is connected to the first power component and the first liquid passage, respectively. The second control valve is located in the second liquid passage and is used at least to perform a closing action on the second liquid passage so that the second liquid passage is in an open state. Before the control device performs a pulling action on a portion of the first fluid path between the first power unit and the first control valve, the control device is configured to: The second control valve is controlled to close the second liquid circuit.

6. The sample processing system as described in claim 5, characterized in that, The cleaning device includes a first cleaning component, which includes a cleaning fluid container, a third fluid passage, and a cleaning swab. One end of the third fluid passage is connected to the cleaning fluid container, and the other end of the third fluid passage is connected to the cleaning swab. The third fluid passage contains at least a portion of the cleaning fluid. The cleaning swab has a receiving space for the pipette to enter and exit, such that the outer wall of the pipette contacts the cleaning swab. The first power component is at least used to perform a pushing action on the third fluid passage, so that the cleaning fluid contained in the third fluid passage flows to the cleaning swab. The control of the cleaning device to perform a cleaning action on the pipette after the completion of the reconstitution dispensing action includes: After the reconstitution solution dispensing operation is completed, the pipette enters the receiving space; Control the first power unit to perform a pushing action on the third hydraulic circuit; After the reconstitution solution dispensing action is completed, the pipette leaves the receiving space; The cleaning fluid container and the system fluid container are the same container, or the cleaning fluid container and the system fluid container are two independent containers.

7. The sample processing system as described in claim 6, characterized in that, The first cleaning component further includes a third control valve, which is disposed in the third liquid passage. The third control valve is used at least to perform a closing action on the third liquid passage so that the third liquid passage is in a connected state. Before the first power unit performs a pushing action on the third liquid path, the control device is configured to: The third control valve is controlled to close the third liquid circuit.

8. The sample processing system as described in claim 5 or 6, characterized in that, The cleaning device includes a second cleaning component, the second cleaning component includes a cleaning tank filled with cleaning fluid, and the first power component is at least used to perform a cleaning fluid aspiration action on the pipette inserted into the cleaning tank, so that the cleaning fluid enters the inner cavity of the pipette, and the first power component is at least also used to perform a cleaning fluid dispensing action on the pipette inserted into the cleaning tank, so that the cleaning fluid flows out from the inner cavity of the pipette. The control of the cleaning device to perform a cleaning action on the pipette after the completion of the reconstitution dispensing action includes: After the reconstitution solution dispensing operation is completed, the pipette is inserted into the cleaning tank; The first power unit is controlled to perform a cleaning fluid aspiration action on the pipette inserted into the cleaning tank; The first power unit is controlled to perform a dispensing action of cleaning fluid to the pipette inserted into the cleaning tank.

9. The sample processing system as described in claim 8, characterized in that, The cleaning device further includes a waste liquid treatment component, which includes a waste liquid tank for loading contaminated cleaning liquid, a second power unit, a fourth liquid path, a fifth liquid path, a sixth liquid path, and a fourth control valve. One end of the fourth liquid path is connected to the waste liquid tank, and the other end of the fourth liquid path is connected to the fourth control valve. One end of the fifth liquid path is connected to the cleaning tank, and the other end of the fifth liquid path is connected to the fourth control valve. One end of the sixth liquid path is connected to the cleaning swab, and the other end of the sixth liquid path is connected to the fourth control valve. The second power unit is located in the fourth liquid path. The fourth control valve has a first state in which the fourth liquid path is connected to the fifth liquid path and a second state in which the fourth liquid path is connected to the sixth liquid path. The second power unit is at least used to provide power to recover the contaminated cleaning liquid in the cleaning tank in the first state, and the second power unit is also used to provide power to recover the contaminated cleaning liquid in the cleaning swab in the second state. Preferably, the sixth liquid path is provided with a filter for filtering the contaminated cleaning liquid.

10. The sample processing system as described in claim 1, characterized in that, The reconstitution device further includes a reconstitution container containing the reconstitution solution, and the pipette is at least used to perform a second puncture on the standard sample container after the first puncture action is completed, so as to at least partially penetrate into the standard sample container; After the control device performs a first puncture operation on one of the at least two standard sample containers containing lyophilized standard samples or lyophilized reagents, and before the control device performs the reconstitution dispensing operation on the standard sample container after the first puncture operation, the control device is configured as follows: Control the pipette to leave the standard sample container after the first puncture action has been completed; Control the pipette to draw at least a portion of the reconstituted solution from the reconstituted solution container; The pipetting is controlled to perform a second puncture on the standard sample container after the first puncture action has been completed.

11. The sample processing system as described in claim 10, characterized in that, After the pipette is removed from the standard sample container where the first puncture action has been completed, and before the pipette is aspirated from the reconstituted solution container, the control device is configured to: The cleaning device is controlled to perform a cleaning action on the pipette after the first puncture is completed.

12. The sample processing system as described in claim 10, characterized in that, The pipette has a groove on its outer wall, which extends along the length of the pipette. The standard sample container includes a bottle body and a cap. The bottle body forms an inner cavity, which is used to hold a lyophilized standard sample and a liquid standard sample reconstituted from the lyophilized standard sample, or to hold a lyophilized reagent and a liquid reagent reconstituted from the lyophilized reagent. The cap seals the inner cavity. When the pipette completes the first puncture, a venting channel is formed between the groove and the cap, and the inner cavity is connected to the external environment through the venting channel to achieve pressure relief. When the pipette completes the second puncture, the venting channel is formed between the groove and the cap, and the venting channel is connected to the external environment to allow the reconstituted solution to be injected into the inner cavity.

13. The sample processing system according to any one of claims 1 to 7 or 10 to 12, characterized in that, The lyophilized standard sample is a lyophilized quality control sample, or the lyophilized standard sample is a lyophilized calibrator.

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