Thrombectomy dual function catheter and thrombectomy device

Abstract

This invention provides a dual-function thrombolysis and thrombolysis device, comprising a multi-lumen tube, a thrombolysis mesh, and a movable cannula; the multi-lumen tube and the movable cannula slide relative to each other axially; the multi-lumen tube has an aspiration chamber, a control wire chamber, and a distally closed thrombolysis chamber; the thrombolysis mesh includes a membrane and a control wire; the membrane includes a tubular body, a tubular channel one, and a tubular channel two; the tubular body is fitted over the distal end of the multi-lumen tube, and its two axially open edges are respectively provided with a wire-passing channel around the tubular body, and its circumferential surface has a side hole one and a side hole two; the tubular channel one connects the side hole one and the thrombolysis chamber; the tubular channel two connects the side hole two and the aspiration chamber; the control wire passes through the wire-passing channel to form a support ring, and its first end is fixed to the movable cannula, and its second end passes through the control wire chamber; in the delivery state, the thrombolysis mesh is retracted inside the movable cannula. This invention enables simultaneous thrombolysis and thrombectomy in a single intervention, improving thrombus removal efficiency and effectiveness, and reducing damage to the patient's body.

Description

Technical Field

[0001] This invention relates to the technical field of medical devices, and in particular to a dual-function catheter and thrombolysis / removal device. Background Technology

[0002] Interventional vascular therapy is an important means of treating vascular diseases such as acute ischemic stroke. It mainly includes two surgical methods: thrombolysis and thrombectomy. Thrombolysis involves infusing thrombolytic drugs into the thrombus site through a catheter to dissolve the thrombus, while thrombectomy involves directly removing the thrombus using a thrombectomy device.

[0003] In existing technologies, after the thrombolytic catheter enters the thrombus site, a occlusion guidewire is usually inserted to assist in the perfusion of the thrombolytic agent. During the perfusion process, blood cannot flow to the affected area, which may damage the distal blood vessels or even lead to necrosis of the distal blood vessels. Therefore, the operation time needs to be shortened as much as possible, but this also increases the urgency and risk of the operation. Thrombolysis and thrombectomy are performed in stages. When the thrombolytic effect is not good, multiple operations are required for thrombolysis or thrombectomy, which increases the risk of the operation and prolongs the patient's recovery period. Summary of the Invention

[0004] The purpose of this invention is to provide a dual-function catheter and device for thrombolysis and thrombolysis to alleviate the aforementioned technical problems in the prior art.

[0005] To achieve the above objectives, the embodiments of the present invention adopt the following technical solutions: In a first aspect, embodiments of the present invention provide a dual-function thrombolysis and thrombectomy catheter, comprising a multi-lumen tube, a thrombolysis and thrombectomy network, and a movable cannula; The multi-lumen tube and the movable sleeve are coaxially arranged and can slide relative to each other along the axial direction; The multi-lumen tube includes a thrombolysis chamber, an aspiration chamber, and a control wire chamber, with the distal end of the thrombolysis chamber closed. The dissolution network includes: The membrane body, made of elastic membrane material, includes a tubular main body, a tubular channel one, and a tubular channel two; the tubular main body is sleeved on the outside of the distal portion of the multi-lumen tube, and its proximal opening edge and distal opening edge are respectively provided with a wire-passing channel around the tubular main body, and its circumferential surface is provided with a side hole one and a side hole two; the tubular channel one connects the side hole one and the thrombolysis chamber; the tubular channel two connects the side hole two and the aspiration chamber; The control wire includes a proximal metal wire and a distal metal wire. The proximal metal wire passes through the wire-passing channel at the proximal end of the tubular body to form a proximal support ring, and the distal metal wire passes through the wire-passing channel at the distal end of the tubular body to form a distal support ring. The first ends of the proximal metal wire and the distal metal wire are fixedly connected to the movable sleeve, and their second ends extend through the control wire cavity to the proximal side of the multi-lumen tube. During transport, the dissolution plug mesh is retracted inside the movable sleeve.

[0006] In an optional embodiment, the first side hole is provided on the circumferential surface of the tubular body near the proximal end of the tubular body, and the second side hole is provided on the circumferential surface of the tubular body near the distal end of the tubular body. And / or, both the tubular channel one and the tubular channel two are inserted into the inner side of the tubular body.

[0007] In an optional embodiment, the proximal opening edge and the distal opening edge of the tubular body are respectively curled to form the threading channel, and the threading channel has a threading opening on one side; And / or, the second end of the proximal metal wire and the second end of the distal metal wire merge and are fixedly connected to form a control wire, which passes through the control wire cavity.

[0008] In an optional embodiment, the inner surface of the suction cavity is provided with a smooth polymer material layer; And / or, the distal end of the multi-lumen tube is provided with a tapered guide head, the tapered guide head having an internal cavity that communicates with the suction cavity and axially extends through the tapered guide head, and in the released state, the tapered guide head is located on the distal side of the tubular body.

[0009] In an optional embodiment, the thrombolysis and thrombectomy dual-function catheter further includes an outer tube sleeved outside the multi-lumen tube; The outer tube is fixed relative to the multi-cavity tube. There is a wiring gap and an annular accommodating cavity with a radial cross-section between the outer circumferential surface of the multi-cavity tube and the inner circumferential surface of the outer tube. The wiring gap is located on the proximal side of the accommodating cavity. The movable sleeve is slidably disposed in the accommodating cavity, and a push-pull metal wire is fixedly connected to the proximal end of the movable sleeve, the push-pull metal wire passing through the wiring gap; The second end of the proximal metal wire and the second end of the distal metal wire pass through the movable sleeve and the control wire cavity and extend to the proximal side of the outer tube.

[0010] In an optional embodiment, the outer surface of the multi-cavity tube is provided with a braided layer made of metal wires, the outer tube is fixed to the outer surface of the braided layer, and the wiring gap is located between the braided layer and the outer surface of the multi-cavity tube.

[0011] In an optional embodiment, the proximal portion of the multi-lumen tube and the outer tube are integrally formed, and the accommodating cavity is formed between the outer peripheral surface of the distal portion of the multi-lumen tube and the inner peripheral surface of the outer tube.

[0012] In an optional embodiment, the push-pull metal wire comprises two wires, which are symmetrically fixed to both sides of the movable sleeve along the radial direction of the movable sleeve.

[0013] In an optional embodiment, a developing ring is fixedly connected to the proximal end of the movable sleeve, and the first ends of the proximal and distal metal wires are both fixedly connected to the developing ring.

[0014] Secondly, embodiments of the present invention also provide a thrombolysis device, including an operating handle and a dual-function thrombolysis catheter as described in any optional embodiment of the first aspect, which includes an outer tube. The proximal end of the outer tube is connected to the operating handle. The operating handle is provided with a thrombolysis channel communicating with the thrombolysis chamber, an aspiration channel communicating with the aspiration chamber, a control wire channel communicating with the control wire chamber, and a push-pull wire channel through which the push-pull metal wire passes.

[0015] The dual-function catheter and thrombolysis / thrombolysis / thrombolysis device provided in this invention can simultaneously dissolve and remove thrombi in a single intervention, improving thrombus removal efficiency and effectiveness while reducing damage to the patient's body. For more specific details on its structure, usage, and functional effects, please refer to the detailed description in the specific embodiments section of this application.

[0016] In particular, in the embodiments of the present invention, "and / or" means that the first feature before "and / or" and the second feature after "and / or" include the following specific settings: (1) only the first feature is set, and the second feature is not set; (2) only the second feature is set, and the first feature is not set; (3) the first feature and the second feature are set at the same time. Attached Figure Description

[0017] To more clearly illustrate the specific embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the specific embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are some embodiments of the present invention. For those skilled in the art, other drawings can be obtained from these drawings without creative effort.

[0018] Figure 1An isometric view of the overall structure of the thrombolysis and thrombectomy dual-function catheter provided in the embodiment of the present invention in the released state (when the thrombolysis and thrombectomy network is released); Figure 2 This is a cross-sectional view of the overall structure of the dual-function thrombectomy catheter provided in an embodiment of the present invention in the released state (when the thrombectomy network is released); Figure 3 for Figure 2 A partial structural diagram of region A in the middle; Figure 4 In the dual-function catheter for thrombolysis and thrombectomy provided in this embodiment of the invention, the isometric view of the proximal portion of the multi-lumen tube and the outer tube assembly structure... Figure 1 ; Figure 5 In the dual-function catheter for thrombolysis and thrombectomy provided in this embodiment of the invention, the isometric view of the proximal portion of the multi-lumen tube and the outer tube assembly structure... Figure 2 ; Figure 6 This is a proximal end face view of the assembly structure of the proximal portion of the multi-lumen tube and the outer tube in the dual-function catheter for thrombolysis and thrombectomy provided in an embodiment of the present invention. Figure 7 This is a distal end view of the assembly structure of the proximal portion of the multi-lumen tube and the outer tube in the dual-function catheter for thrombolysis and thrombectomy provided in an embodiment of the present invention. Figure 8 for Figure 7 FF section view; Figure 9 for Figure 8 A schematic diagram of the partial structure of region B in the middle; Figure 10 This is an isometric structural diagram of the movable cannula in the dual-function catheter for thrombolysis and thrombectomy provided in an embodiment of the present invention. Figure 11 for Figure 10 A schematic diagram of the partial structure of region C in the middle; Figure 12 A cross-sectional view of the movable cannula in the thrombolysis and thrombectomy dual-function catheter provided in an embodiment of the present invention; Figure 13 for Figure 12 A schematic diagram of the local structure of region D in the middle; Figure 14 In the dual-function catheter for thrombolysis and thrombectomy provided in this embodiment of the invention, the isometric view of the assembly structure of the distal portion of the multi-lumen tube and the thrombolysis and thrombectomy mesh is shown. Figure 1 ; Figure 15 In the dual-function catheter for thrombolysis and thrombectomy provided in this embodiment of the invention, the isometric view of the assembly structure of the distal portion of the multi-lumen tube and the thrombolysis and thrombectomy mesh is shown. Figure 2 ; Figure 16 In the dual-function catheter for thrombolysis and thrombectomy provided in this embodiment of the invention, the isometric view of the assembly structure of the distal portion of the multi-lumen tube and the thrombolysis and thrombectomy mesh is shown. Figure 3 .

[0019] Reference numerals: 1-Multi-lumen tube; 101-Conical guide head; 11-Thrombolysis chamber; 12-Aspiration chamber; 13-Control wire chamber; 2-Dissolving the plug mesh; 21-Tubular body; 210-Threading channel; 211-Side hole one; 212-Side hole two; 22-Tubular channel one; 23-Tubular channel two; 3-Moving sleeve; 301-Developing ring; 31-Push-pull wire; 4-Outer tube; 501 - Trace clearance; 502 - Receptacle; 5-Woven layer. Detailed Implementation

[0020] To make the objectives, technical solutions, and advantages of the embodiments of the present invention clearer, the technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. The components of the embodiments of the present invention described and shown in the accompanying drawings can generally be arranged and designed in various different configurations.

[0021] Therefore, the following detailed description of the embodiments of the invention provided in the accompanying drawings is not intended to limit the scope of the claimed invention, but merely to illustrate selected embodiments of the invention. All other embodiments obtained by those skilled in the art based on the embodiments of the invention without inventive effort are within the scope of protection of the invention.

[0022] It should be noted that similar labels and letters in the accompanying drawings indicate similar items. Therefore, once an item is defined in one accompanying drawing, it does not need to be further defined and explained in subsequent accompanying drawings.

[0023] In the description of this invention, it should be noted that: Unless otherwise explicitly specified and limited, the terms "set," "install," and "connect" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this invention based on the specific circumstances.

[0024] The terms “proximal end,” “distal end,” “front end,” “rear end,” “axial,” “radial,” “inner,” and “outer,” etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings, or the orientation or positional relationship in which the product of the invention is usually placed during use. They are used only for the convenience of describing the invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limiting the invention.

[0025] The terms “first”, “second”, etc. are used only for distinguishing descriptions and do not indicate totality or relative position in time and / or space, nor should they be construed as indicating or implying relative importance.

[0026] Below, the end of the medical device closest to the surgeon during surgery is defined as the proximal end of the medical device, and the end of the medical device that enters the patient's blood vessel is defined as the distal end of the medical device (the front end of the medical device is the distal end, and the rear end of the medical device is the proximal end); some embodiments of the present invention will be described in detail with reference to the accompanying drawings.

[0027] First aspect This embodiment provides a dual-function catheter for thrombolysis and thrombectomy.

[0028] Reference Figure 1 and Figure 2 The dual-function thrombectomy catheter includes a multi-lumen tube 1, a thrombectomy net 2, and a movable cannula 3.

[0029] Specifically: the multi-lumen tube 1 and the movable sleeve 3 are coaxially arranged and can slide relative to each other along the axial direction.

[0030] Reference Figures 3 to 7 The lumen of the multi-lumen tube 1 includes a thrombolysis chamber 11, an aspiration chamber 12, and a control wire chamber 13, with the distal end of the thrombolysis chamber 11 closed.

[0031] Reference Figure 1 , Figure 2 as well as Figures 14-16 The dissolution plug network 2 includes a membrane and control wires.

[0032] The membrane is made of elastic membrane material, and its overall structure includes a tubular main body 21, a tubular channel one 22, and a tubular channel two 23. The tubular main body 21 is fitted over the distal portion of the multi-lumen tube 1, and its proximal and distal opening edges are respectively provided with thread-passing channels 210 surrounding the tubular main body 21. Its circumferential surface is provided with side holes one 211 and two side holes two 212. Figures 3 to 7 The tubular channel 22 connects the side hole 211 and the thrombolysis chamber 11 of the multi-lumen tube 1; the tubular channel 23 connects the side hole 212 and the suction chamber 12 of the multi-lumen tube 1.

[0033] The control wire (not shown in the figure) includes a proximal metal wire and a distal metal wire. The proximal metal wire passes through the wire-passing channel 210 at the proximal end of the tubular body 21 to form a proximal support ring. The distal metal wire passes through the wire-passing channel 210 at the distal end of the tubular body 21 to form a distal support ring. The first ends of the proximal and distal metal wires are fixedly connected to the movable sleeve 3. The second ends of the proximal and distal metal wires pass through the control wire cavity 13 of the multi-lumen tube 1 and extend to the proximal side of the multi-lumen tube 1.

[0034] In use, the sleeve 3 and / or the multi-lumen tube 1 are axially slidably moved so that the moving sleeve 3 is fitted outside the dissolution plug 2, and the dissolution plug 2 is retracted inside the moving sleeve 3.

[0035] Insert the guidewire along the established vascular access, and push the distal end of the thrombolytic dual-function catheter along the guidewire to the patient's location, positioning the thrombolytic mesh 2 at the thrombus site. Then withdraw the guidewire. Note: During delivery, keep the thrombolytic mesh 2 retracted within the movable cannula 3 throughout the entire procedure. Then, the cannula 3 is moved axially backward relative to the multi-lumen tube 1, releasing the entire thrombectomy net 2 into the blood vessel. In the structure of the thrombectomy net 2: the proximal and distal metal wires freely spring apart to form a proximal support ring and a distal support ring, respectively, pressing the proximal and distal ends of the tubular body 21 against the inner wall of the blood vessel to form support (the proximal ends of the proximal and distal metal wires are free ends, and the portion located inside the wire-passing channel 210 is pre-formed into a ring, always having a tendency to automatically spring back into a support ring after release). At this time, the membrane of the tubular body 21 adheres to the surface of the thrombus attached to the blood vessel wall. Because the surface of the tubular body 21 is a membrane, and the thrombectomy lumen 11 of the multi-lumen tube 1 is distal... The tubular channel 22 of the thrombolytic network 2 is closed at the end and connects the side hole 211 on the surface of the tubular body 21 to the thrombolytic chamber 11 of the multi-lumen tube 1. Thus, a thrombolytic fluid channel connecting to the thrombus is formed inside the tubular channel 22 and the thrombolytic chamber 11 of the multi-lumen tube 1. At this time, the thrombolytic agent can be introduced into the thrombolytic chamber 11 of the multi-lumen tube 1 through the proximal end of the multi-lumen tube 1, so that the thrombolytic agent can be directly introduced into the thrombus location for efficient thrombolysis. At the same time, since the tubular channel 23 connects the side hole 212 to the aspiration chamber 12 of the multi-lumen tube 1, the thrombus can be aspirated by connecting an aspiration device at the entrance of the aspiration chamber 12 at the proximal end of the multi-lumen tube 1, so that thrombolysis and thrombectomy can be performed simultaneously. After the thrombolysis and thrombectomy are completed, the control wires (proximal and distal metal wires) are withdrawn to close the openings at both ends of the tubular body 21 axially. Then, the cannula 3 and / or the multi-lumen tube 1 are axially slidably moved so that the moving cannula 3 is re-sleeved outside the thrombolysis and thrombectomy net 2, and the thrombolysis and thrombectomy net 2 is contracted inside the moving cannula 3. Finally, the dual-function thrombolysis and thrombectomy catheter is withdrawn.

[0036] The dual-function thrombolysis and thrombectomy catheter provided in this embodiment can simultaneously remove thrombi in a single intervention. After the thrombolysis mesh 2 is released, the membrane of the tubular body 21 adheres to the thrombus surface. When the thrombolytic agent introduced along the thrombolysis chamber 11 of the multi-lumen tube 1 reaches the thrombus surface, the membrane has a certain flow-blocking effect. Although the injected thrombolytic agent will eventually flow away from the gap between the thrombus and the membrane, it can significantly prolong the contact time between the agent and the thrombus, thus improving the thrombolysis effect. Furthermore, during the thrombolysis process, the two ends of the tubular body 21 in the axial direction are opened by the proximal and distal metal wires, establishing a blood passage between the inner side of the tubular body 21 and the outer peripheral surface of the multi-lumen tube 1, preventing ischemia. This design avoids the problem of distal vessel necrosis during the administration of thrombolytic agents. Simultaneously, the dissolved thrombus is promptly aspirated from the patient's body, eliminating the need for an additional basket structure to prevent thrombus escape. This simplifies surgical instruments and prevents secondary embolism caused by thrombus flow. Furthermore, under suction, even softened thrombi that are not completely dissolved can be removed, allowing the thrombolytic agent to target deeper thrombi, further accelerating dissolution and removal. Additionally, thrombolytic drugs can be pre-coated onto the membrane surface of the tubular body 21 to enhance the thrombolytic effect and improve thrombus removal efficiency and effectiveness.

[0037] It should be noted that, in this embodiment, for the multi-lumen tube 1, the following options are available, but not limited to: Figures 14-16 As shown, the multi-lumen tube 1 has a distal portion fitted by a tubular body 21 and a proximal portion fixedly or integrally connected to the proximal side of the distal portion. The distal portion includes at least an aspiration chamber 12, and the proximal portion includes at least three lumens: a thrombolysis chamber 11, an aspiration chamber 12, and a control wire chamber 13. A lateral incision is provided between the distal and proximal portions. The aspiration chamber 12 in the proximal portion communicates with the aspiration chamber 12 in the distal portion. The thrombolysis chamber 11 in the proximal portion has a connection port on the inner surface of the incision. This connection port communicates with a side hole 211 on the surface of the tubular body 21 through a tubular channel 22. The control wire cavity 13 has a connecting port 2 on the inner surface of the incision or on the side of the multi-lumen tube 1. The second end of the proximal metal wire passes through the movable sleeve 3 and then through the control wire cavity 13 of the multi-lumen tube 1 through the connecting port 2. The second end of the distal metal wire first passes through the channel between the inner surface of the tubular body 21 and the distal part of the multi-lumen tube 1, then passes through the movable sleeve 3, and then through the control wire cavity 13 of the multi-lumen tube 1 through the connecting port 2. The second ends of the proximal and distal metal wires can also merge into a single control wire on the proximal side of the tubular body 21 and pass through the control wire cavity 13 of the multi-lumen tube 1 through the connecting port 2. Preferably, the second ends of the proximal and distal metal wires are merged and fixedly connected to form a single control wire that passes through the control wire cavity 13, which facilitates the synchronous opening and closing of both ends of the tubular body 21 and simplifies the surgical procedure.

[0038] For the thrombus detachment network 2, its membrane body can be made of, but is not limited to, PDMS elastomer membrane (Polydimethylsiloxane, a silicone-based polymer with high elasticity, low modulus, high elongation at break, easy assembly and expansion, etc.) or other elastic membrane materials; its tubular body 21 can also have a woven metal mesh pre-set on its inner surface to improve its adhesion to the wall after release. The tubular body 21 can be pre-set to be spindle-shaped in the release state so that it can better adhere to the thrombus surface attached to the blood vessel wall after release.

[0039] Continue to refer to Figures 14 to 16 Furthermore: In an optional embodiment of this example, for the thrombus removal mesh 2, the first side hole 211 is located on the circumferential surface of the tubular body 21 near the proximal end of the tubular body 21, and the second side hole 212 is located on the circumferential surface of the tubular body 21 near the distal end of the tubular body 21. During release, the first side hole 211 can be located upstream of the thrombus in the direction of blood flow, and the second side hole 212 can be located downstream of the thrombus in the direction of blood flow. This allows the thrombolytic agent to flow from one end of the thrombus band to the other end of the thrombus band with the direction of blood flow, and to be aspirated downstream, thereby further improving the thrombus removal effect and surgical efficiency, while further preventing thrombus fragments from flowing with the blood to other areas and causing secondary embolism.

[0040] In an optional embodiment of this invention, both tubular channel one 22 and tubular channel two 23 are designed to be inserted inside the tubular body 21. This structure can simplify the structural complexity of the surgical instruments. At the same time, it can prevent the channels for thrombolysis and thrombus aspiration from being squeezed by the blood vessel wall and the attached thrombus, thus avoiding narrowing or blockage of the channels and improving surgical efficiency (if the channel is narrowed, it may be impossible to aspirate larger thrombi, and if it is blocked, the surgery cannot be performed normally, and the instruments need to be rotated and readjusted, which will increase the complexity of the surgical operation).

[0041] In an optional embodiment of this example, the proximal and distal opening edges of the tubular body 21 are respectively curled to form a threading channel 210, and a threading opening is provided on one side of the threading channel 210. In this optional embodiment, the threading channel 210 serves as an internal guide path, and together with the threading opening provided on one side, it provides a clear and smooth guide channel for threading the control wires (proximal and distal metal wires). The curled threading channel 210 has a certain degree of elasticity and coverage, which can limit and fix the control wires during the threading process, prevent them from coming off or shifting during use, and improve the stability and reliability of the control wires (proximal and distal metal wires) in controlling the opening and closing of the opening edges at both ends of the tubular body 21.

[0042] In an optional embodiment of this invention, the inner surface of the aspiration chamber 12 is provided with a smooth polymer material layer. This polymer material layer can be, but is not limited to, a PTFE (polytetrafluoroethylene) layer. This design makes the surface of the aspiration chamber 12 smooth and less prone to adhesion of substances, so as to effectively prevent thrombi from adhering to the inner wall of the aspiration chamber 12 during the aspiration process, keep the aspiration channel clean, reduce the risk of blockage, and improve aspiration efficiency and smoothness.

[0043] In an optional embodiment of this invention, a tapered guide head 101 is provided at the distal end of the multi-lumen tube 1. The tapered guide head 101 has an internal cavity that communicates with and axially extends through the aspiration chamber 12. In the released state, the tapered guide head 101 is located at the distal end of the tubular body 21. The tapered guide head 101 refers to a tapered structure with a distal diameter smaller than the proximal diameter. This structure allows the distal tip of the thrombolysis / removal dual-function catheter to insert into or pass through a portion of the thrombus when the thrombus blockage at the target location is severe. This allows the tubular body 21 to act on a larger area of ​​the thrombus, improving the accuracy of the surgical location and enhancing the surgical outcome and efficiency.

[0044] In this embodiment, there are several possible structural options for the specific structure in which the multi-lumen tube 1 and the movable sheath 3 are coaxially arranged and can slide relative to each other along the axial direction to contract or release the thrombus retrieval network 2. For example, but not limited to, the movable sheath 3 can be a tube sleeved outside the multi-lumen tube 1 (similar to the push tube of the covered stent implantation device in the prior art). The contraction or release function is achieved by sliding the two tubes relative to each other along the axial direction. However, in this structure, an outer sheath tube needs to be designed in addition to the push tube, which will increase the outer diameter of the overall structure and is not conducive to pushing in narrow blood vessels.

[0045] In this regard, refer to Figures 1 to 13 In an optional embodiment of this example, the dual-function thrombectomy catheter further includes an outer tube 4. The outer tube 4 is sleeved outside the multi-lumen tube 1 and fixed relative to the multi-lumen tube 1. A wiring gap 501 and a receiving cavity 502 with an annular radial cross-section are provided between the outer circumferential surface of the multi-lumen tube 1 and the inner circumferential surface of the outer tube 4. The wiring gap 501 is located on the proximal side of the receiving cavity 502. The movable sleeve 3 is slidably disposed in the receiving cavity 502, and a push-pull metal wire 31 is fixedly connected to the proximal end of the movable sleeve 3. The push-pull metal wire 31 passes through the aforementioned wiring gap 501. The multi-lumen tube 1 has a distal portion sleeved by a tubular body 21 and a proximal portion fixed or integrally connected to the proximal side of the distal portion. The second end of the proximal metal wire and the second end of the distal metal wire pass through the control wire cavity 13 of the movable sleeve 3 and the proximal portion of the multi-lumen tube 1 and extend to the proximal side of the outer tube 4.

[0046] In use, the axial sliding of the movable cannula 3 relative to the multi-lumen tube 1 is controlled by pushing or pulling the metal wire 31 forward or backward along the cable gap 501, allowing the movable cannula 3 to be pulled into or out of the receiving cavity 502. When the movable cannula 3 is pulled into the receiving cavity 502, it no longer radially binds the thrombectomy net 2. When the movable cannula 3 is pushed out of the receiving cavity 502, it is re-wrapped around the thrombectomy net 2 to shrink it (the axial length of the movable cannula 3 must be greater than or equal to the axial length of the thrombectomy net 2 when it is shrunk). In this optional embodiment, the movable cannula 3 does not occupy additional radial dimensions, which can reduce the overall size of the catheter, facilitate passage through narrowed blood vessels, and reduce damage to patient tissues.

[0047] In an optional embodiment of this invention, the outer surface of the multi-lumen tube 1 is provided with a braided layer 5 made of metal wire, and the outer tube 4 is fixed to the outer surface of the braided layer 5. The wiring gap 501 is located between the braided layer 5 and the outer surface of the multi-lumen tube 1. This optional embodiment can increase the compressive strength, flexural strength, and kink resistance of the multi-lumen tube 1 by using the braided layer 5, preventing the multi-lumen tube 1 from deforming or breaking when squeezed. At the same time, it enhances the overall pushing ability of the thrombolysis and thrombectomy dual-function catheter, making it more stable during pushing and reducing bending and deviation caused by softness, allowing doctors to more accurately control the position and direction of the catheter during operation.

[0048] In an optional embodiment of this example, the proximal portion of the multi-lumen tube 1 and the outer tube 4 are integrally formed. A receiving cavity 502 is formed between the outer peripheral surface of the distal portion of the multi-lumen tube 1 and the inner peripheral surface of the outer tube 4. The specific process can be a rheological process, in which the outer tube 4 and the multi-lumen tube 1 are extruded separately, and the separately extruded outer tube 4 and the multi-lumen tube 1 (or a multi-lumen tube with a braided layer 5) are rheologically integrated. During the rheological process, a section at the distal end does not undergo rheological transformation, forming the receiving cavity 502. In this embodiment, the outer tube 4 and the multi-lumen tube 1 are integrated, which simplifies the number of catheter components and the assembly difficulty, reduces the complexity of surgical operations, and helps to further improve surgical efficiency.

[0049] In an optional embodiment of this example, the push-pull metal wire 31 includes two wires. These two push-pull metal wires 31 are symmetrically fixed on both sides of the movable sleeve 3 along the radial direction of the movable sleeve 3. This helps to improve the stability and reliability of the push-pull metal wire 31 when pushing and pulling the movable sleeve 3, avoids the problem of jamming caused by the movable sleeve 3 deflecting to one side during the push-pull process, and improves the smoothness of the push-pull.

[0050] In an optional embodiment of this invention, a contrast ring 301 is fixedly connected to the proximal end of the movable cannula 3. The first ends of the proximal and distal metal wires are both fixedly connected to the contrast ring 301. The design of the contrast ring 301 makes it easier for the surgeon to grasp the current position of the movable cannula 3 with the help of contrast instruments, and to operate more accurately, thereby further improving the success rate of the surgery. The contrast ring 301 can be, but is not limited to, a metal ring welded to the proximal end of the movable cannula 3, or it can be other contrast materials fused together or fixed to the proximal end of the movable cannula 3 in other ways.

[0051] Second aspect This embodiment provides a thrombolysis device, including an operating handle and a dual-function thrombolysis catheter provided by any optional embodiment of the aforementioned first aspect, which includes an outer tube 4. The proximal end of the outer tube 4 in the dual-function thrombolysis catheter is connected to the operating handle. The operating handle is provided with a thrombolysis channel communicating with a thrombolysis chamber 11, an aspiration channel communicating with an aspiration chamber 12, a control wire channel communicating with a control wire chamber 13, and a push-pull wire channel through which a push-pull metal wire 31 passes.

[0052] The specific structure and achievable effects of the thrombolytic dual-function catheter portion of the thrombolytic device provided in this embodiment can be obtained by referring to the optional or preferred embodiments of the first aspect.

[0053] Finally, it should be noted that: In this specification, "and / or" means that the feature before "and / or" and the feature after "and / or" are designed simultaneously or selectively; In this specification, the term "metal" can refer to either pure metal or alloy. The embodiments and optional implementations described above in this specification are only used to illustrate the technical solutions of the present invention, and are not intended to limit them. Although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that modifications can still be made to the technical solutions described in the foregoing optional implementations, or equivalent substitutions can be made to some or all of the technical features therein. These modifications or substitutions do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of the present invention. Furthermore, it is emphasized again that, in the absence of conflict, the features of the embodiments and optional implementations in the embodiments in this specification can be combined with each other.

Claims

1. A dual-function catheter for thrombolysis and thrombectomy, characterized in that, Including multi-lumen tubes, dissolution plugs, and movable cannulas; The multi-lumen tube and the movable sleeve are coaxially arranged and can slide relative to each other along the axial direction; The multi-lumen tube includes a thrombolysis chamber, an aspiration chamber, and a control wire chamber, with the distal end of the thrombolysis chamber closed. The dissolution network includes: The membrane body, made of elastic membrane material, includes a tubular main body, a tubular channel one, and a tubular channel two; the tubular main body is sleeved on the outside of the distal portion of the multi-lumen tube, and its proximal opening edge and distal opening edge are respectively provided with a wire-passing channel around the tubular main body, and its circumferential surface is provided with a side hole one and a side hole two; the tubular channel one connects the side hole one and the thrombolysis chamber; the tubular channel two connects the side hole two and the aspiration chamber; The control wire includes a proximal metal wire and a distal metal wire. The proximal metal wire passes through the wire-passing channel at the proximal end of the tubular body to form a proximal support ring, and the distal metal wire passes through the wire-passing channel at the distal end of the tubular body to form a distal support ring. The first ends of the proximal metal wire and the distal metal wire are fixedly connected to the movable sleeve, and their second ends extend through the control wire cavity to the proximal side of the multi-lumen tube. During transport, the dissolution plug mesh is retracted inside the movable sleeve.

2. The dual-function catheter for thrombolysis and thrombectomy according to claim 1, characterized in that, The first side hole is located on the circumferential surface of the tubular body near the proximal end of the tubular body, and the second side hole is located on the circumferential surface of the tubular body near the distal end of the tubular body. And / or, both the tubular channel one and the tubular channel two are inserted into the inner side of the tubular body.

3. The dual-function catheter for thrombolysis and thrombectomy according to claim 1, characterized in that, The proximal and distal opening edges of the tubular body are respectively curled to form the threading channel, and the threading channel has a threading opening on one side; And / or, the second end of the proximal metal wire and the second end of the distal metal wire merge and are fixedly connected to form a control wire, which passes through the control wire cavity.

4. The dual-function catheter for thrombolysis and thrombectomy according to claim 1, characterized in that, The inner surface of the suction chamber is provided with a smooth polymer material layer; And / or, the distal end of the multi-lumen tube is provided with a tapered guide head, the tapered guide head having an internal cavity that communicates with the suction cavity and axially extends through the tapered guide head, and in the released state, the tapered guide head is located on the distal side of the tubular body.

5. The dual-function thrombolysis and thrombectomy catheter according to any one of claims 1-4, characterized in that, The thrombolytic dual-function catheter also includes an outer tube sleeved outside the multi-lumen tube; The outer tube is fixed relative to the multi-cavity tube. There is a wiring gap and an annular accommodating cavity with a radial cross-section between the outer circumferential surface of the multi-cavity tube and the inner circumferential surface of the outer tube. The wiring gap is located on the proximal side of the accommodating cavity. The movable sleeve is slidably disposed in the accommodating cavity, and a push-pull metal wire is fixedly connected to the proximal end of the movable sleeve, the push-pull metal wire passing through the wiring gap; The second end of the proximal metal wire and the second end of the distal metal wire pass through the movable sleeve and the control wire cavity and extend to the proximal side of the outer tube.

6. The dual-function catheter for thrombolysis and thrombectomy according to claim 5, characterized in that, The outer surface of the multi-cavity tube is provided with a braided layer made of metal wires, the outer tube is fixed to the outer surface of the braided layer, and the wiring gap is located between the braided layer and the outer surface of the multi-cavity tube.

7. The dual-function catheter for thrombolysis and thrombectomy according to claim 5, characterized in that, The proximal portion of the multi-lumen tube and the outer tube are integrally formed, and the accommodating cavity is formed between the outer peripheral surface of the distal portion of the multi-lumen tube and the inner peripheral surface of the outer tube.

8. The dual-function catheter for thrombolysis and thrombectomy according to claim 5, characterized in that, The push-pull metal wires include two wires, which are symmetrically fixed on both sides of the movable sleeve along the radial direction of the movable sleeve.

9. The dual-function catheter for thrombolysis and thrombectomy according to claim 5, characterized in that, The proximal end of the movable sleeve is fixedly connected to a developing ring, and the first end of both the proximal and distal metal wires are fixedly connected to the developing ring.

10. A device for dissolving and removing thrombi, characterized in that, The device includes an operating handle and a dual-function thrombolysis and thrombectomy catheter as described in any one of claims 5-9. The proximal end of the outer tube is connected to the operating handle. The operating handle is provided with a thrombolysis channel communicating with the thrombolysis chamber, an aspiration channel communicating with the aspiration chamber, a control wire channel communicating with the control wire chamber, and a push-pull wire channel for the push-pull metal wire to pass through.

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